locus-tag	class	description
JX573_RS00015	COG2501	S4 domain
JX573_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JX573_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JX573_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JX573_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JX573_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
JX573_RS00110	COG4863	YycH protein
JX573_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JX573_RS00125	COG0737	Belongs to the 5'-nucleotidase family
JX573_RS00150	COG0584	glycerophosphoryl diester phosphodiesterase
JX573_RS00155	COG2030	dehydratase
JX573_RS00275	COG0456	acetyltransferase
JX573_RS00300	COG1073	alpha beta
JX573_RS00310	COG2226	methyltransferase
JX573_RS00320	COG0823	Involved in the tonB-independent uptake of proteins
JX573_RS00340	COG1473	amidohydrolase
JX573_RS00355	COG1283	sodium-dependent phosphate transmembrane transporter activity
JX573_RS00360	COG4716	Myosin-crossreactive antigen
JX573_RS00370	COG1620	l-lactate permease
JX573_RS00385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX573_RS00390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX573_RS00395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JX573_RS00405	COG2423	ornithine cyclodeaminase activity
JX573_RS00410	COG4264	IucA IucC family
JX573_RS00415	COG2814	Major facilitator Superfamily
JX573_RS00420	COG4264	IucA IucC family
JX573_RS00425	COG4264	IucA IucC family
JX573_RS00435	COG0019	diaminopimelate decarboxylase activity
JX573_RS00440	COG1475	DNA binding
JX573_RS00460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JX573_RS00465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JX573_RS00470	COG0438	transferase activity, transferring glycosyl groups
JX573_RS00500	COG0813	purine-nucleoside phosphorylase activity
JX573_RS00505	COG2814	Major facilitator Superfamily
JX573_RS00525	COG3639	organic phosphonate transmembrane transporter activity
JX573_RS00545	COG0737	Belongs to the 5'-nucleotidase family
JX573_RS00560	COG1012	belongs to the aldehyde dehydrogenase family
JX573_RS00560	COG1454	alcohol dehydrogenase
JX573_RS00585	COG1086	Polysaccharide biosynthesis protein
JX573_RS00595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JX573_RS00625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JX573_RS00635	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JX573_RS00640	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JX573_RS00650	COG2832	Protein of unknown function (DUF454)
JX573_RS00685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JX573_RS00690	COG1960	acyl-CoA dehydrogenase activity
JX573_RS00695	COG5609	conserved protein (DUF2294)
JX573_RS00745	COG1114	Component of the transport system for branched-chain amino acids
JX573_RS00750	COG1335	isochorismatase
JX573_RS00755	COG3961	Belongs to the TPP enzyme family
JX573_RS00785	COG1737	Transcriptional regulator
JX573_RS00820	COG0601	transmembrane transport
JX573_RS00825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JX573_RS00835	COG0405	Gamma-glutamyltransferase
JX573_RS00855	COG3842	ATPase activity
JX573_RS00865	COG1175	transmembrane transport
JX573_RS00870	COG3833	ABC-type maltose transport systems, permease component
JX573_RS00875	COG0673	inositol 2-dehydrogenase activity
JX573_RS00880	COG0673	inositol 2-dehydrogenase activity
JX573_RS00890	COG1755	Isoprenylcysteine carboxyl methyltransferase
JX573_RS00945	COG0183	Belongs to the thiolase family
JX573_RS00955	COG1960	acyl-CoA dehydrogenase activity
JX573_RS00960	COG0318	PFAM AMP-dependent synthetase and ligase
JX573_RS00975	COG0747	negative chemotaxis
JX573_RS00980	COG3189	MarR family transcriptional regulator
JX573_RS01005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JX573_RS01005	COG2190	(PTS) system
JX573_RS01005	COG1263	PTS System
JX573_RS01010	COG1957	nucleoside hydrolase
JX573_RS01030	COG3414	Phosphotransferase system galactitol-specific IIB component
JX573_RS01035	COG3775	system Galactitol-specific IIC component
JX573_RS01040	COG1063	alcohol dehydrogenase
JX573_RS01050	COG1063	alcohol dehydrogenase
JX573_RS01060	COG1063	alcohol dehydrogenase
JX573_RS01065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JX573_RS01070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JX573_RS01080	COG1063	alcohol dehydrogenase
JX573_RS01085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JX573_RS01120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JX573_RS01125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JX573_RS01125	COG2190	(PTS) system
JX573_RS01125	COG1263	PTS System
JX573_RS01130	COG2723	6-phospho-beta-galactosidase activity
JX573_RS01135	COG2226	methyltransferase
JX573_RS01190	COG1131	(ABC) transporter
JX573_RS01225	COG1388	LysM domain
JX573_RS01225	COG3942	CHAP domain
JX573_RS01390	COG1114	Component of the transport system for branched-chain amino acids
JX573_RS01395	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JX573_RS01400	COG0577	efflux transmembrane transporter activity
JX573_RS01425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JX573_RS01430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JX573_RS01455	COG3314	Sporulation integral membrane protein YlbJ
JX573_RS01480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JX573_RS01505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JX573_RS01510	COG3037	sugar-specific permease SgaT UlaA
JX573_RS01520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JX573_RS01525	COG3711	transcriptional antiterminator
JX573_RS01545	COG2271	Major facilitator Superfamily
JX573_RS01550	COG0346	lactoylglutathione lyase activity
JX573_RS01555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JX573_RS01560	COG0431	NADPH-dependent FMN reductase
JX573_RS01575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JX573_RS01580	COG2822	iron ion transport
JX573_RS01590	COG0672	)-iron permease
JX573_RS01595	COG0805	protein transport
JX573_RS01600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JX573_RS01610	COG1476	TRANSCRIPTIONal
JX573_RS01620	COG1131	(ABC) transporter
JX573_RS01650	COG0646	methionine synthase
JX573_RS01650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JX573_RS01655	COG0626	cystathionine gamma-synthase activity
JX573_RS01660	COG0626	cystathionine gamma-synthase activity
JX573_RS01665	COG1475	DNA binding
JX573_RS01670	COG0668	transmembrane transport
JX573_RS01675	COG4481	Protein conserved in bacteria
JX573_RS01680	COG0012	GTP binding
JX573_RS01810	COG2233	PERMEase
JX573_RS01850	COG3759	membrane
JX573_RS01980	COG0523	cobalamin synthesis protein
JX573_RS02005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JX573_RS02015	COG5609	conserved protein (DUF2294)
JX573_RS02030	COG1647	Serine aminopeptidase, S33
JX573_RS02040	COG0733	neurotransmitter:sodium symporter activity
JX573_RS02045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JX573_RS02050	COG0626	cystathionine gamma-synthase activity
JX573_RS02060	COG2011	ABC-type metal ion transport system permease component
JX573_RS02065	COG1464	Belongs to the NlpA lipoprotein family
JX573_RS02100	COG0583	DNA-binding transcription factor activity
JX573_RS02105	COG0070	glutamate synthase
JX573_RS02105	COG0069	glutamate synthase activity
JX573_RS02105	COG0067	glutamate synthase
JX573_RS02110	COG0493	'glutamate synthase
JX573_RS02120	COG1263	PTS System
JX573_RS02120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JX573_RS02125	COG0366	Alpha amylase catalytic
JX573_RS02130	COG2188	Transcriptional regulator
JX573_RS02150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JX573_RS02185	COG1982	Orn Lys Arg decarboxylase major
JX573_RS02195	COG3870	Protein conserved in bacteria
JX573_RS02200	COG0470	DNA polymerase III
JX573_RS02205	COG1774	PSP1 C-terminal conserved region
JX573_RS02215	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JX573_RS02225	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JX573_RS02235	COG0084	hydrolase, TatD family'
JX573_RS02240	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JX573_RS02250	COG4466	Protein conserved in bacteria
JX573_RS02260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JX573_RS02265	COG0251	oxidation-reduction process
JX573_RS02305	COG2244	polysaccharide biosynthetic process
JX573_RS02315	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JX573_RS02325	COG1098	S1 RNA binding domain
JX573_RS02340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JX573_RS02365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JX573_RS02460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JX573_RS02475	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JX573_RS02485	COG3880	PFAM UvrB UvrC protein
JX573_RS02500	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JX573_RS02505	COG4956	integral membrane protein (PIN domain superfamily)
JX573_RS02525	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JX573_RS02580	COG2813	Specifically methylates the guanine in position
JX573_RS02620	COG1473	amidohydrolase
JX573_RS02650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JX573_RS02655	COG1428	Deoxynucleoside kinase
JX573_RS02660	COG1428	Deoxynucleoside kinase
JX573_RS02670	COG0561	phosphatase activity
JX573_RS02710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JX573_RS02725	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JX573_RS02815	COG0095	Lipoate-protein ligase
JX573_RS02820	COG0083	homoserine kinase activity
JX573_RS02840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JX573_RS02925	COG0667	Aldo Keto reductase
JX573_RS02930	COG0655	NAD(P)H dehydrogenase (quinone) activity
JX573_RS02940	COG1078	dGTPase activity
JX573_RS02975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JX573_RS02980	COG4139	cobalamin transport
JX573_RS03030	COG4974	Belongs to the 'phage' integrase family
JX573_RS03075	COG0803	Belongs to the bacterial solute-binding protein 9 family
JX573_RS03080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JX573_RS03085	COG1121	(ABC) transporter
JX573_RS03090	COG1321	iron dependent repressor
JX573_RS03100	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JX573_RS03110	COG1682	transport, permease protein
JX573_RS03115	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JX573_RS03125	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JX573_RS03130	COG1686	Belongs to the peptidase S11 family
JX573_RS03135	COG1132	(ABC) transporter
JX573_RS03140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JX573_RS03150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JX573_RS03155	COG1120	ATPase activity
JX573_RS03160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX573_RS03165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX573_RS03170	COG2376	Dihydroxyacetone kinase
JX573_RS03180	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JX573_RS03190	COG3949	Membrane
JX573_RS03210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JX573_RS03225	COG1136	(ABC) transporter
JX573_RS03230	COG0577	efflux transmembrane transporter activity
JX573_RS03235	COG1392	Phosphate transport regulator
JX573_RS03240	COG0306	phosphate transporter
JX573_RS03245	COG1388	LysM domain
JX573_RS03245	COG3942	CHAP domain
JX573_RS03255	COG1917	Cupin 2, conserved barrel domain protein
JX573_RS03255	COG4977	sequence-specific DNA binding
JX573_RS03285	COG0583	DNA-binding transcription factor activity
JX573_RS03290	COG2814	Major facilitator Superfamily
JX573_RS03295	COG2839	Protein conserved in bacteria
JX573_RS03325	COG1611	Belongs to the LOG family
JX573_RS03345	COG4988	ABC transporter
JX573_RS03350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JX573_RS03360	COG0523	cobalamin synthesis protein
JX573_RS03365	COG4989	oxidoreductase activity
JX573_RS03375	COG0471	metal ion transport
JX573_RS03380	COG0415	Belongs to the DNA photolyase family
JX573_RS03410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JX573_RS03415	COG1349	DNA-binding transcription factor activity
JX573_RS03420	COG1105	Belongs to the carbohydrate kinase PfkB family
JX573_RS03425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JX573_RS03425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JX573_RS03425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JX573_RS03430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JX573_RS03435	COG1253	flavin adenine dinucleotide binding
JX573_RS03440	COG0656	L-ascorbic acid biosynthetic process
JX573_RS03445	COG0463	Glycosyl transferase, family 2
JX573_RS03480	COG0720	synthase
JX573_RS03490	COG0512	Glutamine amidotransferase of anthranilate synthase
JX573_RS03490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JX573_RS03495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JX573_RS03525	COG0488	(ABC) transporter
JX573_RS03530	COG0514	ATP-dependent DNA helicase (RecQ)
JX573_RS03535	COG0517	IMP dehydrogenase activity
JX573_RS03535	COG1125	glycine betaine transport
JX573_RS03540	COG1174	glycine betaine transport
JX573_RS03565	COG3104	oligopeptide transport
JX573_RS03585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JX573_RS03590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JX573_RS03600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX573_RS03605	COG4605	iron ion homeostasis
JX573_RS03610	COG4604	ABC transporter, ATP-binding protein
JX573_RS03615	COG4607	ABC-type enterochelin transport system periplasmic component
JX573_RS03670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JX573_RS03675	COG1739	Uncharacterized protein family UPF0029
JX573_RS03685	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JX573_RS03690	COG1040	competence protein
JX573_RS03720	COG1388	LysM domain
JX573_RS03720	COG3942	CHAP domain
JX573_RS03780	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JX573_RS03840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JX573_RS03845	COG1647	Serine aminopeptidase, S33
JX573_RS03850	COG0557	exoribonuclease II activity
JX573_RS04120	COG1278	Cold shock
JX573_RS04160	COG0406	alpha-ribazole phosphatase activity
JX573_RS04165	COG1279	arginine transmembrane transporter activity
JX573_RS04190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JX573_RS04195	COG1393	Belongs to the ArsC family
JX573_RS04205	COG3878	Protein conserved in bacteria
JX573_RS04210	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JX573_RS04225	COG2011	ABC-type metal ion transport system permease component
JX573_RS04230	COG1464	Belongs to the NlpA lipoprotein family
JX573_RS04245	COG0396	ATPase activity
JX573_RS04250	COG0719	Fe-S assembly protein
JX573_RS04260	COG0822	iron-sulfur transferase activity
JX573_RS04280	COG1253	flavin adenine dinucleotide binding
JX573_RS04295	COG1801	Protein of unknown function DUF72
JX573_RS04300	COG0730	response to heat
JX573_RS04315	COG4470	Protein conserved in bacteria
JX573_RS04325	COG2445	Protein of unknown function DUF86
JX573_RS04355	COG1696	Membrane protein involved in D-alanine export
JX573_RS04365	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JX573_RS04370	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JX573_RS04375	COG4837	Protein of unknown function (DUF1462)
JX573_RS04380	COG1252	NADH dehydrogenase
JX573_RS04390	COG0316	Belongs to the HesB IscA family
JX573_RS04400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JX573_RS04405	COG2056	Na+-H+ antiporter family
JX573_RS04410	COG2050	protein possibly involved in aromatic compounds catabolism
JX573_RS04465	COG1098	S1 RNA binding domain
JX573_RS04470	COG1902	pentaerythritol trinitrate reductase activity
JX573_RS04485	COG0584	glycerophosphoryl diester phosphodiesterase
JX573_RS04505	COG0398	Pfam SNARE associated Golgi protein
JX573_RS04550	COG0561	phosphatase activity
JX573_RS04575	COG1881	PFAM PEBP family protein
JX573_RS04605	COG0601	transmembrane transport
JX573_RS04610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JX573_RS04615	COG0444	Belongs to the ABC transporter superfamily
JX573_RS04620	COG4608	Belongs to the ABC transporter superfamily
JX573_RS04625	COG4166	transmembrane transport
JX573_RS04630	COG0747	negative chemotaxis
JX573_RS04635	COG0444	Belongs to the ABC transporter superfamily
JX573_RS04640	COG4608	Belongs to the ABC transporter superfamily
JX573_RS04645	COG0601	transmembrane transport
JX573_RS04650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JX573_RS04675	COG1164	Oligoendopeptidase f
JX573_RS04685	COG2346	COG2346, Truncated hemoglobins
JX573_RS04700	COG2357	RelA SpoT domain protein
JX573_RS04710	COG0564	pseudouridine synthase activity
JX573_RS04715	COG2239	Acts as a magnesium transporter
JX573_RS04720	COG0475	glutathione-regulated potassium exporter activity
JX573_RS04720	COG0569	domain protein
JX573_RS04730	COG0628	permease
JX573_RS04735	COG1115	amino acid carrier protein
JX573_RS04775	COG0861	Integral membrane protein TerC family
JX573_RS04785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JX573_RS04790	COG0737	Belongs to the 5'-nucleotidase family
JX573_RS04805	COG4903	ComK protein
JX573_RS04820	COG4873	Protein conserved in bacteria
JX573_RS04875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JX573_RS04885	COG2314	TM2 domain
JX573_RS04890	COG0456	acetyltransferase
JX573_RS04895	COG1575	Belongs to the MenA family. Type 1 subfamily
JX573_RS04900	COG1169	isochorismate synthase
JX573_RS04910	COG2267	carboxylic ester hydrolase activity
JX573_RS04935	COG0436	Aminotransferase
JX573_RS04940	COG3594	Acyltransferase
JX573_RS04970	COG1316	TRANSCRIPTIONal
JX573_RS04975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JX573_RS05015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JX573_RS05030	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JX573_RS05070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JX573_RS05075	COG4172	Belongs to the ABC transporter superfamily
JX573_RS05080	COG4721	ABC-type cobalt transport system, permease component
JX573_RS05095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JX573_RS05115	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JX573_RS05120	COG1271	oxidase subunit
JX573_RS05125	COG1294	oxidase, subunit
JX573_RS05130	COG0569	domain protein
JX573_RS05195	COG1176	ABC-type spermidine putrescine transport system, permease component I
JX573_RS05200	COG1177	transmembrane transport
JX573_RS05205	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JX573_RS05230	COG0483	inositol monophosphate 1-phosphatase activity
JX573_RS05240	COG1217	gtp-binding protein TYPA
JX573_RS05250	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JX573_RS05260	COG0772	Belongs to the SEDS family
JX573_RS05290	COG3679	Belongs to the UPF0342 family
JX573_RS05310	COG0742	ribosomal rna small subunit methyltransferase
JX573_RS05365	COG4509	Sortase family
JX573_RS05380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JX573_RS05410	COG1796	DNA polymerase
JX573_RS05410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JX573_RS05435	COG2009	succinate dehydrogenase
JX573_RS05440	COG1053	succinate dehydrogenase
JX573_RS05445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JX573_RS05550	COG1288	antiporter activity
JX573_RS05585	COG1011	Hydrolase
JX573_RS05610	COG4839	cell division protein FtsL
JX573_RS05615	COG0768	penicillin binding
JX573_RS05630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JX573_RS05635	COG0849	cell division
JX573_RS05650	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JX573_RS05660	COG0762	integral membrane protein
JX573_RS05665	COG2302	S4 RNA-binding domain
JX573_RS05670	COG3599	regulation of cell shape
JX573_RS05680	COG2514	catechol 2,3-dioxygenase activity
JX573_RS05695	COG0564	pseudouridine synthase activity
JX573_RS05705	COG2233	PERMEase
JX573_RS05750	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JX573_RS05765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JX573_RS05770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JX573_RS05780	COG2314	TM2 domain
JX573_RS05795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JX573_RS05795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JX573_RS05805	COG0631	protein serine/threonine phosphatase activity
JX573_RS05820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JX573_RS05835	COG1302	Protein conserved in bacteria
JX573_RS05880	COG1196	nuclear chromosome segregation
JX573_RS05885	COG0552	protein localization to endoplasmic reticulum
JX573_RS05895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JX573_RS05950	COG2348	transferase activity, transferring amino-acyl groups
JX573_RS05955	COG0758	DNA mediated transformation
JX573_RS06050	COG0195	Participates in both transcription termination and antitermination
JX573_RS06055	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JX573_RS06080	COG0196	riboflavin kinase activity
JX573_RS06105	COG2188	Transcriptional regulator
JX573_RS06110	COG0612	Peptidase, M16
JX573_RS06115	COG0612	Peptidase, M16
JX573_RS06120	COG0300	oxidoreductase activity
JX573_RS06140	COG1058	Belongs to the CinA family
JX573_RS06140	COG1546	Belongs to the CinA family
JX573_RS06160	COG1692	metallophosphoesterase
JX573_RS06165	COG0674	pyruvate-flavodoxin oxidoreductase activity
JX573_RS06165	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JX573_RS06170	COG1013	pyruvate-flavodoxin oxidoreductase activity
JX573_RS06205	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JX573_RS06210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JX573_RS06235	COG1923	regulation of RNA biosynthetic process
JX573_RS06245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JX573_RS06250	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JX573_RS06255	COG0789	Transcriptional regulator
JX573_RS06360	COG1131	(ABC) transporter
JX573_RS06375	COG2197	response regulator
JX573_RS06385	COG1525	nuclease
JX573_RS06400	COG0527	aspartate kinase activity
JX573_RS06405	COG0460	homoserine dehydrogenase
JX573_RS06410	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JX573_RS06435	COG0833	amino acid
JX573_RS06460	COG2340	Cysteine-rich secretory protein family
JX573_RS06495	COG4846	Membrane protein involved in cytochrome C biogenesis
JX573_RS06515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JX573_RS06525	COG0824	Thioesterase
JX573_RS06545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JX573_RS06550	COG1115	amino acid carrier protein
JX573_RS06565	COG0628	permease
JX573_RS06590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JX573_RS06600	COG1363	Peptidase, m42
JX573_RS06605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JX573_RS06610	COG0512	Glutamine amidotransferase of anthranilate synthase
JX573_RS06650	COG0561	phosphatase activity
JX573_RS06695	COG0704	Plays a role in the regulation of phosphate uptake
JX573_RS06705	COG0581	inorganic phosphate transmembrane transporter activity
JX573_RS06710	COG0573	inorganic phosphate transmembrane transporter activity
JX573_RS06730	COG0488	(ABC) transporter
JX573_RS06735	COG0527	aspartate kinase activity
JX573_RS06740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JX573_RS06810	COG4548	von Willebrand factor, type A
JX573_RS06815	COG0714	Associated with various cellular activities
JX573_RS06860	COG0671	phosphoesterase, PA-phosphatase related
JX573_RS06935	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JX573_RS06955	COG0531	amino acid
JX573_RS06970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JX573_RS06975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JX573_RS06990	COG0116	Belongs to the methyltransferase superfamily
JX573_RS07025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JX573_RS07025	COG4499	WXG100 protein secretion system (Wss), protein YukC
JX573_RS07035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JX573_RS07040	COG3935	DnaD domain protein
JX573_RS07065	COG0438	transferase activity, transferring glycosyl groups
JX573_RS07070	COG1694	Mazg nucleotide pyrophosphohydrolase
JX573_RS07075	COG2738	Putative neutral zinc metallopeptidase
JX573_RS07080	COG4347	Protein of unknown function (DUF1405)
JX573_RS07120	COG0142	geranyltranstransferase activity
JX573_RS07175	COG0492	ferredoxin-NADP+ reductase activity
JX573_RS07190	COG0514	ATP-dependent DNA helicase (RecQ)
JX573_RS07200	COG1141	Ferredoxin
JX573_RS07245	COG5002	protein histidine kinase activity
JX573_RS07250	COG0745	RESPONSE REGULATOR receiver
JX573_RS07255	COG1187	pseudouridine synthase activity
JX573_RS07280	COG0735	belongs to the Fur family
JX573_RS07285	COG0494	nUDIX hydrolase
JX573_RS07290	COG0667	Aldo Keto reductase
JX573_RS07300	COG4221	oxidoreductase activity
JX573_RS07315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JX573_RS07325	COG0366	Alpha amylase catalytic
JX573_RS07330	COG1609	Transcriptional regulator
JX573_RS07360	COG2195	Cleaves the N-terminal amino acid of tripeptides
JX573_RS07370	COG4129	membrane
JX573_RS07380	COG0508	dehydrogenase complex catalyzes the overall conversion of
JX573_RS07385	COG0022	dehydrogenase e1 component
JX573_RS07390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JX573_RS07395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JX573_RS07400	COG0497	DNA recombination
JX573_RS07430	COG1302	Protein conserved in bacteria
JX573_RS07435	COG0439	Biotin carboxylase
JX573_RS07440	COG0511	ligase activity, forming carbon-carbon bonds
JX573_RS07450	COG0006	proline dipeptidase activity
JX573_RS07465	COG0095	Lipoate-protein ligase
JX573_RS07470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JX573_RS07515	COG4537	Required for transformation and DNA binding
JX573_RS07520	COG1459	type II secretion system
JX573_RS07525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JX573_RS07530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JX573_RS07535	COG0011	TIGRFAM Protein of
JX573_RS07540	COG1940	carbohydrate kinase activity
JX573_RS07545	COG4483	Protein conserved in bacteria
JX573_RS07555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JX573_RS07565	COG0768	penicillin binding
JX573_RS07580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JX573_RS07585	COG1121	(ABC) transporter
JX573_RS07595	COG0513	Belongs to the DEAD box helicase family
JX573_RS07605	COG2384	SAM-dependent methyltransferase
JX573_RS07625	COG0517	IMP dehydrogenase activity
JX573_RS07645	COG0295	cytidine deaminase activity
JX573_RS07660	COG1702	phosphate starvation-inducible protein PhoH
JX573_RS07675	COG1030	water channel activity
JX573_RS07685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JX573_RS07690	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JX573_RS07720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JX573_RS07735	COG1466	dna polymerase III delta subunit
JX573_RS07740	COG2333	competence protein COMEC
JX573_RS07740	COG0658	competence protein
JX573_RS07745	COG2131	deaminase
JX573_RS07750	COG2183	response to ionizing radiation
JX573_RS07755	COG2226	methyltransferase
JX573_RS07760	COG0799	negative regulation of ribosome biogenesis
JX573_RS07765	COG1713	HD superfamily hydrolase involved in NAD metabolism
JX573_RS07775	COG1534	Rna-binding protein
JX573_RS07785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JX573_RS07790	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JX573_RS07810	COG3177	Filamentation induced by cAMP protein fic
JX573_RS07815	COG1914	H( )-stimulated, divalent metal cation uptake system
JX573_RS07825	COG0439	Biotin carboxylase
JX573_RS07830	COG0511	ligase activity, forming carbon-carbon bonds
JX573_RS07835	COG1984	allophanate hydrolase subunit 2
JX573_RS07840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JX573_RS07855	COG0826	peptidase U32
JX573_RS07860	COG0826	peptidase U32
JX573_RS07890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JX573_RS07905	COG1104	cysteine desulfurase activity
JX573_RS07910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JX573_RS07920	COG3237	CsbD-like
JX573_RS07925	COG1959	2 iron, 2 sulfur cluster binding
JX573_RS07930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JX573_RS07935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JX573_RS07980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JX573_RS07980	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JX573_RS07985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JX573_RS07985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JX573_RS07990	COG1862	Preprotein translocase
JX573_RS08030	COG2868	ribosomal protein
JX573_RS08105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JX573_RS08115	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JX573_RS08120	COG0285	dihydrofolate synthase activity
JX573_RS08130	COG2818	Glycosylase
JX573_RS08165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JX573_RS08200	COG4112	unkown
JX573_RS08220	COG0833	amino acid
JX573_RS08235	COG1484	DNA-dependent DNA replication
JX573_RS08265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JX573_RS08265	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JX573_RS08275	COG5002	protein histidine kinase activity
JX573_RS08280	COG0745	RESPONSE REGULATOR receiver
JX573_RS08290	COG0372	Belongs to the citrate synthase family
JX573_RS08295	COG1113	amino acid transport
JX573_RS08320	COG0281	malic enzyme
JX573_RS08330	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JX573_RS08335	COG4109	DRTGG domain
JX573_RS08375	COG0827	DNA restriction-modification system
JX573_RS08395	COG1104	cysteine desulfurase activity
JX573_RS08410	COG1956	GAF domain-containing protein
JX573_RS08420	COG0584	glycerophosphoryl diester phosphodiesterase
JX573_RS08425	COG1764	response to oxidative stress
JX573_RS08430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JX573_RS08435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JX573_RS08450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JX573_RS08450	COG1263	PTS System
JX573_RS08455	COG0204	Acyl-transferase
JX573_RS08460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JX573_RS08490	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JX573_RS08495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JX573_RS08500	COG0454	-acetyltransferase
JX573_RS08520	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JX573_RS08520	COG1605	Chorismate mutase
JX573_RS08545	COG1674	ftsk spoiiie
JX573_RS08550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JX573_RS08560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JX573_RS08565	COG1363	Peptidase, m42
JX573_RS08575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JX573_RS08585	COG0510	thiamine kinase activity
JX573_RS08605	COG1187	pseudouridine synthase activity
JX573_RS08610	COG2244	polysaccharide biosynthetic process
JX573_RS08615	COG2081	HI0933 family
JX573_RS08635	COG2814	Major facilitator Superfamily
JX573_RS08640	COG1242	4 iron, 4 sulfur cluster binding
JX573_RS08645	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JX573_RS08660	COG2267	carboxylic ester hydrolase activity
JX573_RS08690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JX573_RS08690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JX573_RS08710	COG4193	domain, Protein
JX573_RS08710	COG3266	domain, Protein
JX573_RS08710	COG5632	N-Acetylmuramoyl-L-alanine amidase
JX573_RS08740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JX573_RS08765	COG0656	L-ascorbic acid biosynthetic process
JX573_RS08785	COG1506	peptidase
JX573_RS09015	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JX573_RS09045	COG1131	(ABC) transporter
JX573_RS09050	COG0537	adenosine 5'-monophosphoramidase activity
JX573_RS09080	COG0420	3'-5' exonuclease activity
JX573_RS09105	COG2197	response regulator
JX573_RS09110	COG4585	Histidine kinase
JX573_RS09110	COG2203	Gaf domain
JX573_RS09115	COG0564	pseudouridine synthase activity
JX573_RS09145	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JX573_RS09150	COG1126	abc transporter atp-binding protein
JX573_RS09155	COG0765	amino acid transport
JX573_RS09325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JX573_RS09330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JX573_RS09340	COG4129	membrane
JX573_RS09365	COG1988	membrane-bound metal-dependent
JX573_RS09375	COG1388	LysM domain
JX573_RS09375	COG1134	teichoic acid transport
JX573_RS09405	COG0535	radical SAM domain protein
JX573_RS09410	COG1607	acyl-coa hydrolase
JX573_RS09415	COG2309	aminopeptidase activity
JX573_RS09435	COG1295	ribonuclease BN
JX573_RS09550	COG4851	CamS sex pheromone cAM373 precursor
JX573_RS09560	COG0210	DNA helicase
JX573_RS09570	COG4496	protein, YerC YecD
JX573_RS09605	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JX573_RS09615	COG0077	Prephenate dehydratase
JX573_RS09625	COG0471	metal ion transport
JX573_RS09635	COG1335	isochorismatase
JX573_RS09650	COG1012	belongs to the aldehyde dehydrogenase family
JX573_RS09705	COG1131	(ABC) transporter
JX573_RS09720	COG1725	Transcriptional regulator
JX573_RS09780	COG1388	LysM domain
JX573_RS09780	COG5632	N-Acetylmuramoyl-L-alanine amidase
JX573_RS09825	COG0739	heme binding
JX573_RS09880	COG4695	Portal protein
JX573_RS10120	COG0156	8-amino-7-oxononanoate synthase activity
JX573_RS10125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JX573_RS10190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JX573_RS10195	COG1621	beta-fructofuranosidase activity
JX573_RS10200	COG1609	Transcriptional regulator
JX573_RS10205	COG0004	ammonium transporteR
JX573_RS10210	COG0425	Belongs to the sulfur carrier protein TusA family
JX573_RS10215	COG2391	methyltransferase activity
JX573_RS10225	COG0488	(ABC) transporter
JX573_RS10235	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JX573_RS10245	COG0456	acetyltransferase
JX573_RS10250	COG1214	PFAM Peptidase M22, glycoprotease
JX573_RS10255	COG0802	atpase or kinase
JX573_RS10270	COG0028	Belongs to the TPP enzyme family
JX573_RS10340	COG2183	response to ionizing radiation
JX573_RS10345	COG1191	sigma factor activity
JX573_RS10355	COG1366	Belongs to the anti-sigma-factor antagonist family
JX573_RS10360	COG2208	phosphoserine phosphatase activity
JX573_RS10390	COG3428	Bacterial PH domain
JX573_RS10420	COG2205	protein histidine kinase activity
JX573_RS10425	COG0745	RESPONSE REGULATOR receiver
JX573_RS10435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JX573_RS10445	COG0772	Belongs to the SEDS family
JX573_RS10460	COG1937	Protein conserved in bacteria
JX573_RS10470	COG1418	mRNA catabolic process
JX573_RS10505	COG0629	single-stranded DNA binding
JX573_RS10580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JX573_RS10605	COG0009	L-threonylcarbamoyladenylate synthase
JX573_RS10610	COG2890	protein-(glutamine-N5) methyltransferase activity
JX573_RS10630	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JX573_RS10670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JX573_RS10715	COG0813	purine-nucleoside phosphorylase activity
JX573_RS10720	COG0783	Belongs to the Dps family
JX573_RS10740	COG1482	cell wall glycoprotein biosynthetic process
JX573_RS10745	COG0702	epimerase
JX573_RS10750	COG0640	Transcriptional regulator
JX573_RS10775	COG0561	phosphatase activity
JX573_RS10780	COG1119	ATPase activity
JX573_RS10795	COG3711	transcriptional antiterminator
JX573_RS10825	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JX573_RS10885	COG0489	protein tyrosine kinase activity
JX573_RS10890	COG2814	Major facilitator Superfamily
JX573_RS10905	COG1272	protein, Hemolysin III
JX573_RS10915	COG1988	membrane-bound metal-dependent
JX573_RS10925	COG3314	Sporulation integral membrane protein YlbJ
JX573_RS10930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX573_RS10935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JX573_RS10940	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JX573_RS10950	COG3457	Alanine racemase
JX573_RS10955	COG4264	IucA IucC family
JX573_RS10960	COG2814	Major facilitator Superfamily
JX573_RS10985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JX573_RS10995	COG2130	NADP-dependent
JX573_RS11060	COG0656	L-ascorbic acid biosynthetic process
JX573_RS11065	COG0789	Transcriptional regulator
JX573_RS11075	COG5492	domain, Protein
JX573_RS11095	COG3527	Alpha-acetolactate decarboxylase
JX573_RS11100	COG0028	Belongs to the TPP enzyme family
JX573_RS11175	COG0201	protein transport
JX573_RS11290	COG2252	PERMEase
JX573_RS11340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JX573_RS11400	COG1763	Mo-molybdopterin cofactor biosynthetic process
JX573_RS11420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JX573_RS11425	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JX573_RS11430	COG4149	molybdate abc transporter
JX573_RS11435	COG0725	ABC transporter, periplasmic molybdate-binding protein
JX573_RS11450	COG1268	BioY protein
JX573_RS11465	COG1960	acyl-CoA dehydrogenase activity
JX573_RS11470	COG4413	Urea transporter
JX573_RS11540	COG1757	Na H antiporter
JX573_RS11555	COG3942	CHAP domain
JX573_RS11625	COG1113	amino acid transport
JX573_RS11645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JX573_RS11650	COG0385	Bile acid
JX573_RS11660	COG1263	PTS System
JX573_RS11660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JX573_RS11665	COG1737	Transcriptional regulator
JX573_RS11685	COG1028	Short-chain dehydrogenase reductase Sdr
JX573_RS11690	COG1473	amidohydrolase
JX573_RS11705	COG0583	DNA-binding transcription factor activity
JX573_RS11725	COG2258	MOSC domain
JX573_RS11745	COG1668	transmembrane transport
JX573_RS11750	COG4152	abc transporter atp-binding protein
JX573_RS11755	COG3152	Membrane
JX573_RS11765	COG0786	glutamate:sodium symporter activity
JX573_RS11775	COG0598	Magnesium transport protein CorA
JX573_RS11790	COG0657	acetylesterase activity
JX573_RS11800	COG2814	Major facilitator Superfamily
JX573_RS11805	COG1566	PFAM secretion protein HlyD family protein
JX573_RS11815	COG2814	Major facilitator Superfamily
JX573_RS11880	COG1620	l-lactate permease
JX573_RS11900	COG0604	alcohol dehydrogenase
JX573_RS11905	COG0456	acetyltransferase
JX573_RS11925	COG1511	domain protein
JX573_RS11955	COG3871	stress protein (general stress protein 26)
JX573_RS11995	COG0789	Transcriptional regulator
JX573_RS12015	COG2181	nitrate reductase activity
JX573_RS12025	COG1140	nitrate reductase beta subunit
JX573_RS12030	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JX573_RS12040	COG2146	nitrite reductase [NAD(P)H] activity
JX573_RS12045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JX573_RS12055	COG0454	-acetyltransferase
JX573_RS12065	COG2116	formate transmembrane transporter activity
JX573_RS12080	COG3443	Belongs to the bacterial solute-binding protein 9 family
JX573_RS12080	COG0803	Belongs to the bacterial solute-binding protein 9 family
JX573_RS12120	COG1126	abc transporter atp-binding protein
JX573_RS12125	COG0765	amino acid transport
JX573_RS12130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JX573_RS12135	COG2814	Major facilitator Superfamily
JX573_RS12150	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JX573_RS12190	COG0156	8-amino-7-oxononanoate synthase activity
JX573_RS12200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JX573_RS12205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JX573_RS12215	COG1132	(ABC) transporter
JX573_RS12220	COG2375	cellular response to nickel ion
JX573_RS12220	COG1132	(ABC) transporter
JX573_RS12235	COG1929	Belongs to the glycerate kinase type-1 family
JX573_RS12245	COG2814	Major facilitator Superfamily
JX573_RS12265	COG1113	amino acid transport
JX573_RS12275	COG0531	amino acid
JX573_RS12290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JX573_RS12300	COG1174	glycine betaine transport
JX573_RS12310	COG1174	glycine betaine transport
JX573_RS12330	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JX573_RS12335	COG0531	amino acid
JX573_RS12340	COG2272	Belongs to the type-B carboxylesterase lipase family
JX573_RS12345	COG2814	Major facilitator Superfamily
JX573_RS12350	COG0390	transport system, permease component
JX573_RS12355	COG4619	ABC transporter
JX573_RS12360	COG1363	Peptidase, m42
JX573_RS12375	COG4808	Protein conserved in bacteria
JX573_RS12380	COG0069	glutamate synthase activity
JX573_RS12395	COG1124	(ABC) transporter
JX573_RS12405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JX573_RS12445	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JX573_RS12450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JX573_RS12550	COG0494	nUDIX hydrolase
JX573_RS12590	COG1846	Transcriptional regulator
JX573_RS12620	COG1070	Carbohydrate kinase
JX573_RS12625	COG1802	Transcriptional regulator
JX573_RS12630	COG0789	Transcriptional regulator
JX573_RS12635	COG2357	RelA SpoT domain protein
JX573_RS12640	COG4876	unkown
JX573_RS12650	COG2271	Major facilitator Superfamily
JX573_RS12655	COG0586	Pfam SNARE associated Golgi protein
JX573_RS12660	COG1131	(ABC) transporter
JX573_RS12675	COG3949	Membrane
JX573_RS12680	COG0400	carboxylic ester hydrolase activity
JX573_RS12685	COG0346	lactoylglutathione lyase activity
JX573_RS12690	COG1846	Transcriptional regulator
JX573_RS12700	COG2514	catechol 2,3-dioxygenase activity
JX573_RS12715	COG0561	phosphatase activity
JX573_RS12720	COG1131	(ABC) transporter
JX573_RS12730	COG3764	Sortase (surface protein transpeptidase)
JX573_RS12750	COG1760	l-serine dehydratase
JX573_RS12755	COG1760	l-serine dehydratase
JX573_RS12770	COG0697	spore germination
JX573_RS12775	COG0657	acetylesterase activity
JX573_RS12795	COG0028	Belongs to the TPP enzyme family
JX573_RS12810	COG0583	DNA-binding transcription factor activity
JX573_RS12820	COG3942	CHAP domain
JX573_RS12830	COG3425	synthase
JX573_RS12835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JX573_RS12860	COG2409	Drug exporters of the RND superfamily
JX573_RS12905	COG0436	Aminotransferase
JX573_RS12935	COG3942	CHAP domain
JX573_RS12940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JX573_RS12940	COG2755	lipolytic protein G-D-S-L family
JX573_RS12945	COG0456	acetyltransferase
JX573_RS13010	COG0596	Alpha beta hydrolase
JX573_RS13050	COG3001	Fructosamine kinase
JX573_RS13055	COG0167	dihydroorotate dehydrogenase activity
JX573_RS13105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JX573_RS13110	COG3527	Alpha-acetolactate decarboxylase
JX573_RS13120	COG0531	amino acid
JX573_RS13150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JX573_RS13170	COG1012	belongs to the aldehyde dehydrogenase family
JX573_RS13180	COG1510	regulation of RNA biosynthetic process
JX573_RS13185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JX573_RS13210	COG2851	Citrate transporter
JX573_RS13225	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JX573_RS13235	COG0386	Belongs to the glutathione peroxidase family
JX573_RS13255	COG1136	(ABC) transporter
JX573_RS13260	COG2205	protein histidine kinase activity
JX573_RS13265	COG0745	RESPONSE REGULATOR receiver
JX573_RS13275	COG1785	Belongs to the alkaline phosphatase family
JX573_RS13285	COG1846	Transcriptional regulator
JX573_RS13330	COG1438	arginine binding
JX573_RS13350	COG3711	transcriptional antiterminator
JX573_RS13350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JX573_RS13355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JX573_RS13355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JX573_RS13355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JX573_RS13360	COG1482	cell wall glycoprotein biosynthetic process
JX573_RS13370	COG1705	Flagellar rod assembly protein muramidase FlgJ
JX573_RS13370	COG3942	CHAP domain
JX573_RS13375	COG1535	isochorismatase
JX573_RS13375	COG3433	isochorismatase activity
JX573_RS13390	COG0438	transferase activity, transferring glycosyl groups
JX573_RS13405	COG1073	alpha beta
JX573_RS13425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JX573_RS13445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JX573_RS13535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JX573_RS13620	COG0471	metal ion transport
JX573_RS13625	COG2962	Rard protein
JX573_RS13635	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JX573_RS13650	COG1136	(ABC) transporter
JX573_RS13655	COG0577	efflux transmembrane transporter activity
JX573_RS13690	COG1278	Cold shock
JX573_RS13710	COG1475	DNA binding
JX573_RS13780	COG3682	Transcriptional regulator
JX573_RS13815	COG0577	efflux transmembrane transporter activity
JX573_RS13815	COG1136	(ABC) transporter