locus-tag	class	description
H8N04_RS00015	COG2501	S4 domain
H8N04_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H8N04_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H8N04_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H8N04_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
H8N04_RS00110	COG4863	YycH protein
H8N04_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H8N04_RS00150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H8N04_RS00150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H8N04_RS00195	COG0584	glycerophosphoryl diester phosphodiesterase
H8N04_RS00200	COG2030	dehydratase
H8N04_RS00250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H8N04_RS00290	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
H8N04_RS00295	COG1353	crispr-associated protein
H8N04_RS00300	COG1421	Csm2 Type III-A
H8N04_RS00305	COG1337	RAMP superfamily
H8N04_RS00310	COG1567	CRISPR-associated RAMP protein, Csm4 family
H8N04_RS00315	COG1332	CRISPR-associated RAMP protein, Csm5 family
H8N04_RS00340	COG1002	Type II restriction enzyme, methylase subunits
H8N04_RS00350	COG2801	Transposase and inactivated derivatives
H8N04_RS00355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H8N04_RS00365	COG0745	RESPONSE REGULATOR receiver
H8N04_RS00370	COG2205	protein histidine kinase activity
H8N04_RS00380	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H8N04_RS00385	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H8N04_RS00390	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H8N04_RS00415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H8N04_RS00445	COG0640	Transcriptional regulator
H8N04_RS00460	COG1064	alcohol dehydrogenase
H8N04_RS00520	COG0655	NAD(P)H dehydrogenase (quinone) activity
H8N04_RS00535	COG1073	alpha beta
H8N04_RS00555	COG0823	Involved in the tonB-independent uptake of proteins
H8N04_RS00580	COG1473	amidohydrolase
H8N04_RS00590	COG1283	sodium-dependent phosphate transmembrane transporter activity
H8N04_RS00595	COG4716	Myosin-crossreactive antigen
H8N04_RS00615	COG1620	l-lactate permease
H8N04_RS00630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H8N04_RS00635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H8N04_RS00640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H8N04_RS00650	COG2423	ornithine cyclodeaminase activity
H8N04_RS00655	COG4264	IucA IucC family
H8N04_RS00660	COG2814	Major facilitator Superfamily
H8N04_RS00665	COG4264	IucA IucC family
H8N04_RS00670	COG4264	IucA IucC family
H8N04_RS00680	COG0019	diaminopimelate decarboxylase activity
H8N04_RS00685	COG1475	DNA binding
H8N04_RS00705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H8N04_RS00715	COG0438	transferase activity, transferring glycosyl groups
H8N04_RS00750	COG2814	Major facilitator Superfamily
H8N04_RS00770	COG3639	organic phosphonate transmembrane transporter activity
H8N04_RS00790	COG0737	Belongs to the 5'-nucleotidase family
H8N04_RS00810	COG1454	alcohol dehydrogenase
H8N04_RS00810	COG1012	belongs to the aldehyde dehydrogenase family
H8N04_RS00835	COG1086	Polysaccharide biosynthesis protein
H8N04_RS00845	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H8N04_RS00875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H8N04_RS00885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H8N04_RS00890	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H8N04_RS00900	COG2832	Protein of unknown function (DUF454)
H8N04_RS00935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H8N04_RS00940	COG1960	acyl-CoA dehydrogenase activity
H8N04_RS00945	COG5609	conserved protein (DUF2294)
H8N04_RS00985	COG2801	Transposase and inactivated derivatives
H8N04_RS00995	COG1785	Belongs to the alkaline phosphatase family
H8N04_RS01005	COG0745	RESPONSE REGULATOR receiver
H8N04_RS01010	COG2205	protein histidine kinase activity
H8N04_RS01015	COG1136	(ABC) transporter
H8N04_RS01035	COG0386	Belongs to the glutathione peroxidase family
H8N04_RS01045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H8N04_RS01060	COG2851	Citrate transporter
H8N04_RS01085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H8N04_RS01095	COG1510	regulation of RNA biosynthetic process
H8N04_RS01105	COG1012	belongs to the aldehyde dehydrogenase family
H8N04_RS01125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H8N04_RS01155	COG0531	amino acid
H8N04_RS01165	COG3527	Alpha-acetolactate decarboxylase
H8N04_RS01170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H8N04_RS01180	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H8N04_RS01220	COG0167	dihydroorotate dehydrogenase activity
H8N04_RS01225	COG3001	Fructosamine kinase
H8N04_RS01260	COG0596	Alpha beta hydrolase
H8N04_RS01325	COG2801	Transposase and inactivated derivatives
H8N04_RS01340	COG2755	lipolytic protein G-D-S-L family
H8N04_RS01340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H8N04_RS01345	COG3942	CHAP domain
H8N04_RS01375	COG0436	Aminotransferase
H8N04_RS01440	COG0542	response to heat
H8N04_RS01445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H8N04_RS01450	COG3425	synthase
H8N04_RS01475	COG3942	CHAP domain
H8N04_RS01485	COG0583	DNA-binding transcription factor activity
H8N04_RS01500	COG0028	Belongs to the TPP enzyme family
H8N04_RS01520	COG0657	acetylesterase activity
H8N04_RS01525	COG0697	spore germination
H8N04_RS01540	COG1760	l-serine dehydratase
H8N04_RS01545	COG1760	l-serine dehydratase
H8N04_RS01565	COG3764	Sortase (surface protein transpeptidase)
H8N04_RS01575	COG1131	(ABC) transporter
H8N04_RS01580	COG0561	phosphatase activity
H8N04_RS01595	COG2514	catechol 2,3-dioxygenase activity
H8N04_RS01605	COG1846	Transcriptional regulator
H8N04_RS01610	COG0346	lactoylglutathione lyase activity
H8N04_RS01615	COG0400	carboxylic ester hydrolase activity
H8N04_RS01620	COG3949	Membrane
H8N04_RS01635	COG1131	(ABC) transporter
H8N04_RS01640	COG1846	Transcriptional regulator
H8N04_RS01645	COG2814	Major facilitator Superfamily
H8N04_RS01655	COG0586	Pfam SNARE associated Golgi protein
H8N04_RS01660	COG2271	Major facilitator Superfamily
H8N04_RS01670	COG4876	unkown
H8N04_RS01675	COG2357	RelA SpoT domain protein
H8N04_RS01680	COG0789	Transcriptional regulator
H8N04_RS01685	COG1802	Transcriptional regulator
H8N04_RS01690	COG1070	Carbohydrate kinase
H8N04_RS01705	COG4932	domain protein
H8N04_RS01715	COG2801	Transposase and inactivated derivatives
H8N04_RS01730	COG1846	Transcriptional regulator
H8N04_RS01735	COG1846	Transcriptional regulator
H8N04_RS01770	COG0494	nUDIX hydrolase
H8N04_RS01855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H8N04_RS01860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H8N04_RS01890	COG0747	negative chemotaxis
H8N04_RS01895	COG0601	transmembrane transport
H8N04_RS01900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H8N04_RS01905	COG0444	Belongs to the ABC transporter superfamily
H8N04_RS01910	COG1124	(ABC) transporter
H8N04_RS01925	COG0069	glutamate synthase activity
H8N04_RS01930	COG4808	Protein conserved in bacteria
H8N04_RS01945	COG1363	Peptidase, m42
H8N04_RS01950	COG4619	ABC transporter
H8N04_RS01955	COG0390	transport system, permease component
H8N04_RS01960	COG2814	Major facilitator Superfamily
H8N04_RS01965	COG2272	Belongs to the type-B carboxylesterase lipase family
H8N04_RS01970	COG0531	amino acid
H8N04_RS01975	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
H8N04_RS01995	COG1174	glycine betaine transport
H8N04_RS02005	COG1174	glycine betaine transport
H8N04_RS02015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H8N04_RS02025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H8N04_RS02030	COG0531	amino acid
H8N04_RS02040	COG1113	amino acid transport
H8N04_RS02060	COG2814	Major facilitator Superfamily
H8N04_RS02070	COG1929	Belongs to the glycerate kinase type-1 family
H8N04_RS02085	COG2375	cellular response to nickel ion
H8N04_RS02085	COG1132	(ABC) transporter
H8N04_RS02090	COG1132	(ABC) transporter
H8N04_RS02100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H8N04_RS02105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H8N04_RS02115	COG0156	8-amino-7-oxononanoate synthase activity
H8N04_RS02155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H8N04_RS02170	COG2814	Major facilitator Superfamily
H8N04_RS02175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H8N04_RS02180	COG0765	amino acid transport
H8N04_RS02185	COG1126	abc transporter atp-binding protein
H8N04_RS02245	COG0803	Belongs to the bacterial solute-binding protein 9 family
H8N04_RS02245	COG3443	Belongs to the bacterial solute-binding protein 9 family
H8N04_RS02260	COG2116	formate transmembrane transporter activity
H8N04_RS02265	COG0454	-acetyltransferase
H8N04_RS02275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H8N04_RS02280	COG2146	nitrite reductase [NAD(P)H] activity
H8N04_RS02290	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H8N04_RS02295	COG1140	nitrate reductase beta subunit
H8N04_RS02305	COG2181	nitrate reductase activity
H8N04_RS02325	COG0789	Transcriptional regulator
H8N04_RS02365	COG3871	stress protein (general stress protein 26)
H8N04_RS02380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H8N04_RS02380	COG1263	PTS System
H8N04_RS02395	COG1511	domain protein
H8N04_RS02415	COG0456	acetyltransferase
H8N04_RS02420	COG0604	alcohol dehydrogenase
H8N04_RS02440	COG1620	l-lactate permease
H8N04_RS02505	COG2814	Major facilitator Superfamily
H8N04_RS02515	COG1566	PFAM secretion protein HlyD family protein
H8N04_RS02520	COG2814	Major facilitator Superfamily
H8N04_RS02530	COG0657	acetylesterase activity
H8N04_RS02545	COG0598	Magnesium transport protein CorA
H8N04_RS02555	COG0786	glutamate:sodium symporter activity
H8N04_RS02570	COG4152	abc transporter atp-binding protein
H8N04_RS02575	COG1668	transmembrane transport
H8N04_RS02595	COG2258	MOSC domain
H8N04_RS02620	COG0583	DNA-binding transcription factor activity
H8N04_RS02635	COG1473	amidohydrolase
H8N04_RS02640	COG1028	Short-chain dehydrogenase reductase Sdr
H8N04_RS02660	COG1737	Transcriptional regulator
H8N04_RS02665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H8N04_RS02665	COG1263	PTS System
H8N04_RS02675	COG0385	Bile acid
H8N04_RS02680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H8N04_RS02700	COG1113	amino acid transport
H8N04_RS02775	COG3942	CHAP domain
H8N04_RS02790	COG1757	Na H antiporter
H8N04_RS02800	COG3942	CHAP domain
H8N04_RS02860	COG4413	Urea transporter
H8N04_RS02865	COG1960	acyl-CoA dehydrogenase activity
H8N04_RS02880	COG1268	BioY protein
H8N04_RS02895	COG0725	ABC transporter, periplasmic molybdate-binding protein
H8N04_RS02900	COG4149	molybdate abc transporter
H8N04_RS02905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H8N04_RS02910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H8N04_RS02930	COG1763	Mo-molybdopterin cofactor biosynthetic process
H8N04_RS02990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H8N04_RS03035	COG2252	PERMEase
H8N04_RS03150	COG0201	protein transport
H8N04_RS03235	COG0542	response to heat
H8N04_RS03255	COG0028	Belongs to the TPP enzyme family
H8N04_RS03260	COG3527	Alpha-acetolactate decarboxylase
H8N04_RS03280	COG5492	domain, Protein
H8N04_RS03295	COG0656	L-ascorbic acid biosynthetic process
H8N04_RS03315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H8N04_RS03365	COG2130	NADP-dependent
H8N04_RS03375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H8N04_RS03405	COG2814	Major facilitator Superfamily
H8N04_RS03410	COG4264	IucA IucC family
H8N04_RS03415	COG3457	Alanine racemase
H8N04_RS03425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H8N04_RS03430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H8N04_RS03435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H8N04_RS03440	COG3314	Sporulation integral membrane protein YlbJ
H8N04_RS03450	COG1988	membrane-bound metal-dependent
H8N04_RS03460	COG1272	protein, Hemolysin III
H8N04_RS03475	COG2814	Major facilitator Superfamily
H8N04_RS03480	COG0489	protein tyrosine kinase activity
H8N04_RS03550	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H8N04_RS03570	COG0246	Mannitol dehydrogenase
H8N04_RS03580	COG3711	transcriptional antiterminator
H8N04_RS03595	COG1119	ATPase activity
H8N04_RS03600	COG0561	phosphatase activity
H8N04_RS03635	COG0640	Transcriptional regulator
H8N04_RS03640	COG0702	epimerase
H8N04_RS03645	COG1482	cell wall glycoprotein biosynthetic process
H8N04_RS03665	COG0783	Belongs to the Dps family
H8N04_RS03670	COG0813	purine-nucleoside phosphorylase activity
H8N04_RS03715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H8N04_RS03725	COG0504	CTP synthase activity
H8N04_RS03755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H8N04_RS03775	COG2890	protein-(glutamine-N5) methyltransferase activity
H8N04_RS03780	COG0009	L-threonylcarbamoyladenylate synthase
H8N04_RS03805	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H8N04_RS03880	COG0629	single-stranded DNA binding
H8N04_RS03915	COG1418	mRNA catabolic process
H8N04_RS03925	COG1937	Protein conserved in bacteria
H8N04_RS03940	COG0772	Belongs to the SEDS family
H8N04_RS03950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H8N04_RS03960	COG2801	Transposase and inactivated derivatives
H8N04_RS03970	COG0745	RESPONSE REGULATOR receiver
H8N04_RS03975	COG2205	protein histidine kinase activity
H8N04_RS04005	COG3428	Bacterial PH domain
H8N04_RS04035	COG2208	phosphoserine phosphatase activity
H8N04_RS04040	COG1366	Belongs to the anti-sigma-factor antagonist family
H8N04_RS04050	COG1191	sigma factor activity
H8N04_RS04055	COG2183	response to ionizing radiation
H8N04_RS04105	COG0473	3-isopropylmalate dehydrogenase activity
H8N04_RS04125	COG0028	Belongs to the TPP enzyme family
H8N04_RS04140	COG0802	atpase or kinase
H8N04_RS04145	COG1214	PFAM Peptidase M22, glycoprotease
H8N04_RS04150	COG0456	acetyltransferase
H8N04_RS04160	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H8N04_RS04170	COG0488	(ABC) transporter
H8N04_RS04180	COG2391	methyltransferase activity
H8N04_RS04185	COG0425	Belongs to the sulfur carrier protein TusA family
H8N04_RS04190	COG0004	ammonium transporteR
H8N04_RS04195	COG1609	Transcriptional regulator
H8N04_RS04200	COG1621	beta-fructofuranosidase activity
H8N04_RS04205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H8N04_RS04240	COG2801	Transposase and inactivated derivatives
H8N04_RS04280	COG0582	viral genome integration into host DNA
H8N04_RS04285	COG1396	sequence-specific DNA binding
H8N04_RS04360	COG5484	DNA packaging
H8N04_RS04360	COG3728	DNA packaging
H8N04_RS04380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H8N04_RS04385	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H8N04_RS04390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H8N04_RS04395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H8N04_RS04405	COG2801	Transposase and inactivated derivatives
H8N04_RS04460	COG1725	Transcriptional regulator
H8N04_RS04475	COG1131	(ABC) transporter
H8N04_RS04530	COG1012	belongs to the aldehyde dehydrogenase family
H8N04_RS04545	COG1335	isochorismatase
H8N04_RS04555	COG0471	metal ion transport
H8N04_RS04565	COG0077	Prephenate dehydratase
H8N04_RS04575	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H8N04_RS04610	COG4496	protein, YerC YecD
H8N04_RS04620	COG0210	DNA helicase
H8N04_RS04630	COG4851	CamS sex pheromone cAM373 precursor
H8N04_RS04740	COG2197	response regulator
H8N04_RS04745	COG1295	ribonuclease BN
H8N04_RS04765	COG2309	aminopeptidase activity
H8N04_RS04770	COG1607	acyl-coa hydrolase
H8N04_RS04775	COG0535	radical SAM domain protein
H8N04_RS04805	COG1134	teichoic acid transport
H8N04_RS04805	COG1388	LysM domain
H8N04_RS04815	COG1988	membrane-bound metal-dependent
H8N04_RS04840	COG4129	membrane
H8N04_RS04850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H8N04_RS04855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H8N04_RS05030	COG0765	amino acid transport
H8N04_RS05035	COG1126	abc transporter atp-binding protein
H8N04_RS05040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H8N04_RS05070	COG0564	pseudouridine synthase activity
H8N04_RS05075	COG2203	Gaf domain
H8N04_RS05075	COG4585	Histidine kinase
H8N04_RS05080	COG2197	response regulator
H8N04_RS05105	COG0420	3'-5' exonuclease activity
H8N04_RS05135	COG0537	adenosine 5'-monophosphoramidase activity
H8N04_RS05140	COG1131	(ABC) transporter
H8N04_RS05170	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H8N04_RS05240	COG2801	Transposase and inactivated derivatives
H8N04_RS05320	COG2801	Transposase and inactivated derivatives
H8N04_RS05340	COG3682	Transcriptional regulator
H8N04_RS05380	COG2855	membrane
H8N04_RS05385	COG0583	DNA-binding transcription factor activity
H8N04_RS05395	COG2801	Transposase and inactivated derivatives
H8N04_RS05520	COG0656	L-ascorbic acid biosynthetic process
H8N04_RS05545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H8N04_RS05565	COG1595	DNA-templated transcription, initiation
H8N04_RS05575	COG4193	domain, Protein
H8N04_RS05575	COG5632	N-Acetylmuramoyl-L-alanine amidase
H8N04_RS05575	COG3266	domain, Protein
H8N04_RS05600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H8N04_RS05600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H8N04_RS05630	COG2267	carboxylic ester hydrolase activity
H8N04_RS05645	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H8N04_RS05650	COG1242	4 iron, 4 sulfur cluster binding
H8N04_RS05655	COG2814	Major facilitator Superfamily
H8N04_RS05675	COG2081	HI0933 family
H8N04_RS05680	COG2244	polysaccharide biosynthetic process
H8N04_RS05685	COG1187	pseudouridine synthase activity
H8N04_RS05705	COG0510	thiamine kinase activity
H8N04_RS05715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H8N04_RS05725	COG1363	Peptidase, m42
H8N04_RS05730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H8N04_RS05740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H8N04_RS05745	COG1674	ftsk spoiiie
H8N04_RS05770	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H8N04_RS05770	COG1605	Chorismate mutase
H8N04_RS05790	COG0454	-acetyltransferase
H8N04_RS05795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H8N04_RS05800	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H8N04_RS05810	COG5386	Cell surface protein
H8N04_RS05830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H8N04_RS05835	COG0204	Acyl-transferase
H8N04_RS05840	COG1263	PTS System
H8N04_RS05840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H8N04_RS05855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H8N04_RS05860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H8N04_RS05865	COG1764	response to oxidative stress
H8N04_RS05870	COG0584	glycerophosphoryl diester phosphodiesterase
H8N04_RS05885	COG1956	GAF domain-containing protein
H8N04_RS05900	COG1104	cysteine desulfurase activity
H8N04_RS05920	COG0827	DNA restriction-modification system
H8N04_RS05960	COG4109	DRTGG domain
H8N04_RS05965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H8N04_RS05970	COG0587	DNA-directed DNA polymerase activity
H8N04_RS05975	COG0281	malic enzyme
H8N04_RS06005	COG1113	amino acid transport
H8N04_RS06010	COG0372	Belongs to the citrate synthase family
H8N04_RS06020	COG0745	RESPONSE REGULATOR receiver
H8N04_RS06025	COG5002	protein histidine kinase activity
H8N04_RS06035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H8N04_RS06035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H8N04_RS06065	COG1484	DNA-dependent DNA replication
H8N04_RS06075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H8N04_RS06080	COG0833	amino acid
H8N04_RS06100	COG4112	unkown
H8N04_RS06130	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H8N04_RS06135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H8N04_RS06170	COG2818	Glycosylase
H8N04_RS06180	COG0285	dihydrofolate synthase activity
H8N04_RS06185	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H8N04_RS06230	COG2868	ribosomal protein
H8N04_RS06270	COG1862	Preprotein translocase
H8N04_RS06275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H8N04_RS06275	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H8N04_RS06280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H8N04_RS06280	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H8N04_RS06310	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H8N04_RS06325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H8N04_RS06330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H8N04_RS06335	COG1959	2 iron, 2 sulfur cluster binding
H8N04_RS06340	COG3237	CsbD-like
H8N04_RS06350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H8N04_RS06355	COG1104	cysteine desulfurase activity
H8N04_RS06370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H8N04_RS06400	COG0826	peptidase U32
H8N04_RS06405	COG0826	peptidase U32
H8N04_RS06420	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H8N04_RS06425	COG1984	allophanate hydrolase subunit 2
H8N04_RS06430	COG0511	ligase activity, forming carbon-carbon bonds
H8N04_RS06435	COG0439	Biotin carboxylase
H8N04_RS06445	COG1914	H( )-stimulated, divalent metal cation uptake system
H8N04_RS06450	COG3177	Filamentation induced by cAMP protein fic
H8N04_RS06470	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H8N04_RS06475	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H8N04_RS06485	COG1534	Rna-binding protein
H8N04_RS06495	COG1713	HD superfamily hydrolase involved in NAD metabolism
H8N04_RS06500	COG0799	negative regulation of ribosome biogenesis
H8N04_RS06505	COG2226	methyltransferase
H8N04_RS06515	COG2131	deaminase
H8N04_RS06520	COG0658	competence protein
H8N04_RS06520	COG2333	competence protein COMEC
H8N04_RS06525	COG1466	dna polymerase III delta subunit
H8N04_RS06540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H8N04_RS06570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H8N04_RS06575	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H8N04_RS06585	COG1030	water channel activity
H8N04_RS06600	COG1702	phosphate starvation-inducible protein PhoH
H8N04_RS06615	COG0295	cytidine deaminase activity
H8N04_RS06620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H8N04_RS06635	COG0517	IMP dehydrogenase activity
H8N04_RS06655	COG2384	SAM-dependent methyltransferase
H8N04_RS06665	COG0513	Belongs to the DEAD box helicase family
H8N04_RS06675	COG1121	(ABC) transporter
H8N04_RS06680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H8N04_RS06695	COG0768	penicillin binding
H8N04_RS06705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H8N04_RS06715	COG4483	Protein conserved in bacteria
H8N04_RS06720	COG1940	carbohydrate kinase activity
H8N04_RS06725	COG0011	TIGRFAM Protein of
H8N04_RS06730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H8N04_RS06735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H8N04_RS06745	COG4537	Required for transformation and DNA binding
H8N04_RS06790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H8N04_RS06795	COG0095	Lipoate-protein ligase
H8N04_RS06810	COG0006	proline dipeptidase activity
H8N04_RS06820	COG0511	ligase activity, forming carbon-carbon bonds
H8N04_RS06825	COG0439	Biotin carboxylase
H8N04_RS06830	COG1302	Protein conserved in bacteria
H8N04_RS06860	COG0497	DNA recombination
H8N04_RS06865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H8N04_RS06870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H8N04_RS06875	COG0022	dehydrogenase e1 component
H8N04_RS06880	COG0508	dehydrogenase complex catalyzes the overall conversion of
H8N04_RS06890	COG4129	membrane
H8N04_RS06900	COG2195	Cleaves the N-terminal amino acid of tripeptides
H8N04_RS06920	COG1609	Transcriptional regulator
H8N04_RS06925	COG0366	Alpha amylase catalytic
H8N04_RS06935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H8N04_RS06950	COG4221	oxidoreductase activity
H8N04_RS06960	COG0667	Aldo Keto reductase
H8N04_RS06965	COG0494	nUDIX hydrolase
H8N04_RS06970	COG0735	belongs to the Fur family
H8N04_RS06995	COG1187	pseudouridine synthase activity
H8N04_RS07000	COG0745	RESPONSE REGULATOR receiver
H8N04_RS07005	COG5002	protein histidine kinase activity
H8N04_RS07050	COG1141	Ferredoxin
H8N04_RS07060	COG0514	ATP-dependent DNA helicase (RecQ)
H8N04_RS07075	COG0492	ferredoxin-NADP+ reductase activity
H8N04_RS07130	COG0142	geranyltranstransferase activity
H8N04_RS07150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H8N04_RS07165	COG5582	Belongs to the UPF0302 family
H8N04_RS07170	COG4347	Protein of unknown function (DUF1405)
H8N04_RS07175	COG2738	Putative neutral zinc metallopeptidase
H8N04_RS07180	COG1694	Mazg nucleotide pyrophosphohydrolase
H8N04_RS07185	COG0438	transferase activity, transferring glycosyl groups
H8N04_RS07210	COG3935	DnaD domain protein
H8N04_RS07215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H8N04_RS07225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H8N04_RS07225	COG4499	WXG100 protein secretion system (Wss), protein YukC
H8N04_RS07260	COG0116	Belongs to the methyltransferase superfamily
H8N04_RS07275	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H8N04_RS07280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H8N04_RS07285	COG0686	Belongs to the AlaDH PNT family
H8N04_RS07295	COG0531	amino acid
H8N04_RS07315	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H8N04_RS07330	COG1413	lyase activity
H8N04_RS07385	COG2801	Transposase and inactivated derivatives
H8N04_RS07400	COG0671	phosphoesterase, PA-phosphatase related
H8N04_RS07445	COG0714	Associated with various cellular activities
H8N04_RS07450	COG4548	von Willebrand factor, type A
H8N04_RS07525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H8N04_RS07530	COG0527	aspartate kinase activity
H8N04_RS07535	COG0488	(ABC) transporter
H8N04_RS07555	COG0573	inorganic phosphate transmembrane transporter activity
H8N04_RS07560	COG0581	inorganic phosphate transmembrane transporter activity
H8N04_RS07570	COG0704	Plays a role in the regulation of phosphate uptake
H8N04_RS07615	COG0561	phosphatase activity
H8N04_RS07655	COG0512	Glutamine amidotransferase of anthranilate synthase
H8N04_RS07660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H8N04_RS07665	COG1363	Peptidase, m42
H8N04_RS07675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H8N04_RS07695	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H8N04_RS07695	COG0392	lysyltransferase activity
H8N04_RS07700	COG0628	permease
H8N04_RS07715	COG1115	amino acid carrier protein
H8N04_RS07720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H8N04_RS07740	COG0824	Thioesterase
H8N04_RS07750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H8N04_RS07770	COG4846	Membrane protein involved in cytochrome C biogenesis
H8N04_RS07805	COG2340	Cysteine-rich secretory protein family
H8N04_RS07830	COG0833	amino acid
H8N04_RS07855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H8N04_RS07860	COG0460	homoserine dehydrogenase
H8N04_RS07865	COG0527	aspartate kinase activity
H8N04_RS07880	COG1525	nuclease
H8N04_RS07890	COG2197	response regulator
H8N04_RS07905	COG1131	(ABC) transporter
H8N04_RS07995	COG2801	Transposase and inactivated derivatives
H8N04_RS08020	COG0789	Transcriptional regulator
H8N04_RS08025	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H8N04_RS08030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H8N04_RS08040	COG1923	regulation of RNA biosynthetic process
H8N04_RS08065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H8N04_RS08070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H8N04_RS08105	COG1013	pyruvate-flavodoxin oxidoreductase activity
H8N04_RS08110	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H8N04_RS08110	COG0674	pyruvate-flavodoxin oxidoreductase activity
H8N04_RS08115	COG1692	metallophosphoesterase
H8N04_RS08135	COG1058	Belongs to the CinA family
H8N04_RS08135	COG1546	Belongs to the CinA family
H8N04_RS08155	COG0300	oxidoreductase activity
H8N04_RS08160	COG0612	Peptidase, M16
H8N04_RS08165	COG0612	Peptidase, M16
H8N04_RS08170	COG2188	Transcriptional regulator
H8N04_RS08195	COG0196	riboflavin kinase activity
H8N04_RS08215	COG1358	cellular component organization or biogenesis
H8N04_RS08220	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H8N04_RS08225	COG0195	Participates in both transcription termination and antitermination
H8N04_RS08320	COG0758	DNA mediated transformation
H8N04_RS08380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H8N04_RS08390	COG0552	protein localization to endoplasmic reticulum
H8N04_RS08395	COG1196	nuclear chromosome segregation
H8N04_RS08430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H8N04_RS08440	COG2801	Transposase and inactivated derivatives
H8N04_RS08450	COG1302	Protein conserved in bacteria
H8N04_RS08465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H8N04_RS08480	COG0631	protein serine/threonine phosphatase activity
H8N04_RS08490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H8N04_RS08490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H8N04_RS08505	COG2314	TM2 domain
H8N04_RS08515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H8N04_RS08520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H8N04_RS08535	COG1293	RNA-binding protein homologous to eukaryotic snRNP
H8N04_RS08580	COG2233	PERMEase
H8N04_RS08590	COG0564	pseudouridine synthase activity
H8N04_RS08605	COG2514	catechol 2,3-dioxygenase activity
H8N04_RS08615	COG3599	regulation of cell shape
H8N04_RS08620	COG2302	S4 RNA-binding domain
H8N04_RS08625	COG0762	integral membrane protein
H8N04_RS08635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H8N04_RS08650	COG0849	cell division
H8N04_RS08655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H8N04_RS08670	COG0768	penicillin binding
H8N04_RS08675	COG4839	cell division protein FtsL
H8N04_RS08700	COG1011	Hydrolase
H8N04_RS08735	COG1288	antiporter activity
H8N04_RS08840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H8N04_RS08845	COG1053	succinate dehydrogenase
H8N04_RS08850	COG2009	succinate dehydrogenase
H8N04_RS08875	COG1796	DNA polymerase
H8N04_RS08875	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H8N04_RS08905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H8N04_RS08920	COG4509	Sortase family
H8N04_RS08975	COG0742	ribosomal rna small subunit methyltransferase
H8N04_RS08995	COG3679	Belongs to the UPF0342 family
H8N04_RS09025	COG0772	Belongs to the SEDS family
H8N04_RS09035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H8N04_RS09045	COG1217	gtp-binding protein TYPA
H8N04_RS09055	COG0483	inositol monophosphate 1-phosphatase activity
H8N04_RS09080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H8N04_RS09085	COG1177	transmembrane transport
H8N04_RS09090	COG1176	ABC-type spermidine putrescine transport system, permease component I
H8N04_RS09155	COG0569	domain protein
H8N04_RS09160	COG1294	oxidase, subunit
H8N04_RS09165	COG1271	oxidase subunit
H8N04_RS09190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H8N04_RS09205	COG4721	ABC-type cobalt transport system, permease component
H8N04_RS09210	COG4172	Belongs to the ABC transporter superfamily
H8N04_RS09215	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H8N04_RS09225	COG0138	bifunctional purine biosynthesis protein purh
H8N04_RS09255	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H8N04_RS09270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H8N04_RS09310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H8N04_RS09315	COG1316	TRANSCRIPTIONal
H8N04_RS09345	COG3594	Acyltransferase
H8N04_RS09350	COG0436	Aminotransferase
H8N04_RS09375	COG2267	carboxylic ester hydrolase activity
H8N04_RS09385	COG1169	isochorismate synthase
H8N04_RS09390	COG1575	Belongs to the MenA family. Type 1 subfamily
H8N04_RS09395	COG0456	acetyltransferase
H8N04_RS09400	COG2314	TM2 domain
H8N04_RS09410	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H8N04_RS09470	COG4873	Protein conserved in bacteria
H8N04_RS09485	COG4903	ComK protein
H8N04_RS09500	COG0737	Belongs to the 5'-nucleotidase family
H8N04_RS09505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H8N04_RS09515	COG0861	Integral membrane protein TerC family
H8N04_RS09555	COG1115	amino acid carrier protein
H8N04_RS09560	COG0628	permease
H8N04_RS09570	COG0569	domain protein
H8N04_RS09570	COG0475	glutathione-regulated potassium exporter activity
H8N04_RS09575	COG2239	Acts as a magnesium transporter
H8N04_RS09580	COG0564	pseudouridine synthase activity
H8N04_RS09590	COG2357	RelA SpoT domain protein
H8N04_RS09605	COG2346	COG2346, Truncated hemoglobins
H8N04_RS09615	COG1164	Oligoendopeptidase f
H8N04_RS09640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H8N04_RS09645	COG0601	transmembrane transport
H8N04_RS09650	COG4608	Belongs to the ABC transporter superfamily
H8N04_RS09655	COG0444	Belongs to the ABC transporter superfamily
H8N04_RS09660	COG0747	negative chemotaxis
H8N04_RS09665	COG4166	transmembrane transport
H8N04_RS09670	COG4608	Belongs to the ABC transporter superfamily
H8N04_RS09675	COG0444	Belongs to the ABC transporter superfamily
H8N04_RS09680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H8N04_RS09685	COG0601	transmembrane transport
H8N04_RS09715	COG1881	PFAM PEBP family protein
H8N04_RS09730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H8N04_RS09755	COG0561	phosphatase activity
H8N04_RS09795	COG0398	Pfam SNARE associated Golgi protein
H8N04_RS09815	COG0584	glycerophosphoryl diester phosphodiesterase
H8N04_RS09830	COG1902	pentaerythritol trinitrate reductase activity
H8N04_RS09835	COG1098	S1 RNA binding domain
H8N04_RS09855	COG2946	Replication initiation factor
H8N04_RS09875	COG0433	COG0433 Predicted ATPase
H8N04_RS09890	COG1388	LysM domain
H8N04_RS09890	COG3942	CHAP domain
H8N04_RS09910	COG2826	transposase and inactivated derivatives, IS30 family
H8N04_RS09965	COG2050	protein possibly involved in aromatic compounds catabolism
H8N04_RS09970	COG2056	Na+-H+ antiporter family
H8N04_RS09975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H8N04_RS09985	COG0316	Belongs to the HesB IscA family
H8N04_RS09995	COG1252	NADH dehydrogenase
H8N04_RS10000	COG4837	Protein of unknown function (DUF1462)
H8N04_RS10005	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H8N04_RS10010	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H8N04_RS10020	COG1696	Membrane protein involved in D-alanine export
H8N04_RS10050	COG2445	Protein of unknown function DUF86
H8N04_RS10060	COG4470	Protein conserved in bacteria
H8N04_RS10075	COG0730	response to heat
H8N04_RS10080	COG1801	Protein of unknown function DUF72
H8N04_RS10095	COG1253	flavin adenine dinucleotide binding
H8N04_RS10115	COG0822	iron-sulfur transferase activity
H8N04_RS10125	COG0719	Fe-S assembly protein
H8N04_RS10130	COG0396	ATPase activity
H8N04_RS10145	COG1464	Belongs to the NlpA lipoprotein family
H8N04_RS10150	COG2011	ABC-type metal ion transport system permease component
H8N04_RS10165	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H8N04_RS10170	COG3878	Protein conserved in bacteria
H8N04_RS10180	COG1393	Belongs to the ArsC family
H8N04_RS10185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H8N04_RS10210	COG1279	arginine transmembrane transporter activity
H8N04_RS10215	COG0406	alpha-ribazole phosphatase activity
H8N04_RS10255	COG1278	Cold shock
H8N04_RS10325	COG0557	exoribonuclease II activity
H8N04_RS10330	COG1647	Serine aminopeptidase, S33
H8N04_RS10335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H8N04_RS10395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H8N04_RS10450	COG3942	CHAP domain
H8N04_RS10450	COG1388	LysM domain
H8N04_RS10480	COG1040	competence protein
H8N04_RS10485	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H8N04_RS10495	COG1739	Uncharacterized protein family UPF0029
H8N04_RS10500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H8N04_RS10555	COG4607	ABC-type enterochelin transport system periplasmic component
H8N04_RS10560	COG4604	ABC transporter, ATP-binding protein
H8N04_RS10565	COG4605	iron ion homeostasis
H8N04_RS10570	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H8N04_RS10580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H8N04_RS10585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H8N04_RS10605	COG3104	oligopeptide transport
H8N04_RS10630	COG1174	glycine betaine transport
H8N04_RS10635	COG0517	IMP dehydrogenase activity
H8N04_RS10635	COG1125	glycine betaine transport
H8N04_RS10640	COG0514	ATP-dependent DNA helicase (RecQ)
H8N04_RS10645	COG0488	(ABC) transporter
H8N04_RS10675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H8N04_RS10680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H8N04_RS10680	COG0512	Glutamine amidotransferase of anthranilate synthase
H8N04_RS10690	COG0720	synthase
H8N04_RS10730	COG2801	Transposase and inactivated derivatives
H8N04_RS10735	COG0463	Glycosyl transferase, family 2
H8N04_RS10740	COG0656	L-ascorbic acid biosynthetic process
H8N04_RS10745	COG1253	flavin adenine dinucleotide binding
H8N04_RS10750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H8N04_RS10755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H8N04_RS10755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H8N04_RS10755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H8N04_RS10760	COG1105	Belongs to the carbohydrate kinase PfkB family
H8N04_RS10765	COG1349	DNA-binding transcription factor activity
H8N04_RS10770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H8N04_RS10800	COG0415	Belongs to the DNA photolyase family
H8N04_RS10805	COG0471	metal ion transport
H8N04_RS10815	COG4989	oxidoreductase activity
H8N04_RS10820	COG0523	cobalamin synthesis protein
H8N04_RS10830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H8N04_RS10835	COG4988	ABC transporter
H8N04_RS10855	COG1611	Belongs to the LOG family
H8N04_RS10885	COG2839	Protein conserved in bacteria
H8N04_RS10890	COG2814	Major facilitator Superfamily
H8N04_RS10895	COG0583	DNA-binding transcription factor activity
H8N04_RS10925	COG4977	sequence-specific DNA binding
H8N04_RS10925	COG1917	Cupin 2, conserved barrel domain protein
H8N04_RS10935	COG1388	LysM domain
H8N04_RS10935	COG3942	CHAP domain
H8N04_RS10940	COG0306	phosphate transporter
H8N04_RS10945	COG1392	Phosphate transport regulator
H8N04_RS10950	COG0577	efflux transmembrane transporter activity
H8N04_RS10955	COG1136	(ABC) transporter
H8N04_RS10970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H8N04_RS10990	COG3949	Membrane
H8N04_RS11000	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
H8N04_RS11010	COG2376	Dihydroxyacetone kinase
H8N04_RS11015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H8N04_RS11020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H8N04_RS11025	COG1120	ATPase activity
H8N04_RS11030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H8N04_RS11040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H8N04_RS11045	COG1132	(ABC) transporter
H8N04_RS11050	COG1686	Belongs to the peptidase S11 family
H8N04_RS11055	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H8N04_RS11060	COG1216	Glycosyl transferase, family 2
H8N04_RS11065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H8N04_RS11070	COG1682	transport, permease protein
H8N04_RS11080	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H8N04_RS11090	COG1321	iron dependent repressor
H8N04_RS11095	COG1121	(ABC) transporter
H8N04_RS11100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H8N04_RS11105	COG0803	Belongs to the bacterial solute-binding protein 9 family
H8N04_RS11150	COG4974	Belongs to the 'phage' integrase family
H8N04_RS11200	COG4139	cobalamin transport
H8N04_RS11205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H8N04_RS11240	COG1078	dGTPase activity
H8N04_RS11250	COG0655	NAD(P)H dehydrogenase (quinone) activity
H8N04_RS11255	COG0667	Aldo Keto reductase
H8N04_RS11355	COG0860	N-Acetylmuramoyl-L-alanine amidase
H8N04_RS11355	COG1388	LysM domain
H8N04_RS11465	COG1783	phage Terminase large subunit
H8N04_RS11500	COG0756	dUTP diphosphatase activity
H8N04_RS11570	COG1484	DNA-dependent DNA replication
H8N04_RS11635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H8N04_RS11680	COG0083	homoserine kinase activity
H8N04_RS11685	COG0095	Lipoate-protein ligase
H8N04_RS11775	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H8N04_RS11790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H8N04_RS11820	COG0561	phosphatase activity
H8N04_RS11830	COG1428	Deoxynucleoside kinase
H8N04_RS11835	COG1428	Deoxynucleoside kinase
H8N04_RS11840	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H8N04_RS11870	COG1473	amidohydrolase
H8N04_RS11910	COG2813	Specifically methylates the guanine in position
H8N04_RS11965	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H8N04_RS11985	COG4956	integral membrane protein (PIN domain superfamily)
H8N04_RS11990	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H8N04_RS12005	COG3880	PFAM UvrB UvrC protein
H8N04_RS12015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H8N04_RS12030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H8N04_RS12110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H8N04_RS12135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H8N04_RS12150	COG1098	S1 RNA binding domain
H8N04_RS12160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H8N04_RS12165	COG3956	TIGRFAM MazG family protein
H8N04_RS12170	COG2244	polysaccharide biosynthetic process
H8N04_RS12210	COG0251	oxidation-reduction process
H8N04_RS12215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H8N04_RS12225	COG4466	Protein conserved in bacteria
H8N04_RS12235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H8N04_RS12240	COG0084	hydrolase, TatD family'
H8N04_RS12250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H8N04_RS12260	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H8N04_RS12270	COG1774	PSP1 C-terminal conserved region
H8N04_RS12275	COG0470	DNA polymerase III
H8N04_RS12280	COG3870	Protein conserved in bacteria
H8N04_RS12290	COG1982	Orn Lys Arg decarboxylase major
H8N04_RS12330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H8N04_RS12350	COG2188	Transcriptional regulator
H8N04_RS12355	COG0366	Alpha amylase catalytic
H8N04_RS12360	COG1263	PTS System
H8N04_RS12360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H8N04_RS12370	COG0493	'glutamate synthase
H8N04_RS12375	COG0069	glutamate synthase activity
H8N04_RS12375	COG0070	glutamate synthase
H8N04_RS12375	COG0067	glutamate synthase
H8N04_RS12380	COG0583	DNA-binding transcription factor activity
H8N04_RS12415	COG1464	Belongs to the NlpA lipoprotein family
H8N04_RS12420	COG2011	ABC-type metal ion transport system permease component
H8N04_RS12430	COG0626	cystathionine gamma-synthase activity
H8N04_RS12435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H8N04_RS12440	COG0733	neurotransmitter:sodium symporter activity
H8N04_RS12450	COG1647	Serine aminopeptidase, S33
H8N04_RS12465	COG5609	conserved protein (DUF2294)
H8N04_RS12475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H8N04_RS12500	COG0523	cobalamin synthesis protein
H8N04_RS12655	COG3759	membrane
H8N04_RS12690	COG2233	PERMEase
H8N04_RS12720	COG1823	symporter activity
H8N04_RS12735	COG3634	alkyl hydroperoxide reductase activity
H8N04_RS12825	COG3728	DNA packaging
H8N04_RS12825	COG5484	DNA packaging
H8N04_RS12940	COG0012	GTP binding
H8N04_RS12945	COG4481	Protein conserved in bacteria
H8N04_RS12950	COG0668	transmembrane transport
H8N04_RS12955	COG1475	DNA binding
H8N04_RS12960	COG0626	cystathionine gamma-synthase activity
H8N04_RS12965	COG0626	cystathionine gamma-synthase activity
H8N04_RS12970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H8N04_RS12970	COG0646	methionine synthase
H8N04_RS13000	COG1131	(ABC) transporter
H8N04_RS13010	COG1476	TRANSCRIPTIONal
H8N04_RS13020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H8N04_RS13025	COG0805	protein transport
H8N04_RS13030	COG0672	)-iron permease
H8N04_RS13040	COG2822	iron ion transport
H8N04_RS13045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H8N04_RS13060	COG0431	NADPH-dependent FMN reductase
H8N04_RS13065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H8N04_RS13070	COG0346	lactoylglutathione lyase activity
H8N04_RS13075	COG2271	Major facilitator Superfamily
H8N04_RS13095	COG3711	transcriptional antiterminator
H8N04_RS13100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H8N04_RS13110	COG3037	sugar-specific permease SgaT UlaA
H8N04_RS13140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H8N04_RS13165	COG3314	Sporulation integral membrane protein YlbJ
H8N04_RS13190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H8N04_RS13195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H8N04_RS13220	COG0577	efflux transmembrane transporter activity
H8N04_RS13225	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
H8N04_RS13230	COG1114	Component of the transport system for branched-chain amino acids
H8N04_RS13310	COG2801	Transposase and inactivated derivatives
H8N04_RS13385	COG1388	LysM domain
H8N04_RS13385	COG3942	CHAP domain
H8N04_RS13415	COG1131	(ABC) transporter
H8N04_RS13465	COG2226	methyltransferase
H8N04_RS13470	COG2723	6-phospho-beta-galactosidase activity
H8N04_RS13475	COG1263	PTS System
H8N04_RS13475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H8N04_RS13475	COG2190	(PTS) system
H8N04_RS13480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H8N04_RS13510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H8N04_RS13535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H8N04_RS13550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H8N04_RS13555	COG1957	nucleoside hydrolase
H8N04_RS13560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H8N04_RS13560	COG1263	PTS System
H8N04_RS13560	COG2190	(PTS) system
H8N04_RS13585	COG3189	MarR family transcriptional regulator
H8N04_RS13590	COG0747	negative chemotaxis
H8N04_RS13595	COG1073	alpha beta
H8N04_RS13625	COG0318	PFAM AMP-dependent synthetase and ligase
H8N04_RS13630	COG1960	acyl-CoA dehydrogenase activity
H8N04_RS13640	COG0183	Belongs to the thiolase family
H8N04_RS13695	COG1755	Isoprenylcysteine carboxyl methyltransferase
H8N04_RS13705	COG0673	inositol 2-dehydrogenase activity
H8N04_RS13710	COG0673	inositol 2-dehydrogenase activity
H8N04_RS13715	COG3833	ABC-type maltose transport systems, permease component
H8N04_RS13720	COG1175	transmembrane transport
H8N04_RS13730	COG3842	ATPase activity
H8N04_RS13750	COG0405	Gamma-glutamyltransferase
H8N04_RS13760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H8N04_RS13790	COG1737	Transcriptional regulator
H8N04_RS13820	COG3961	Belongs to the TPP enzyme family
H8N04_RS13825	COG1335	isochorismatase
H8N04_RS13830	COG1114	Component of the transport system for branched-chain amino acids
H8N04_RS13860	COG2801	Transposase and inactivated derivatives
H8N04_RS13870	COG0583	DNA-binding transcription factor activity
H8N04_RS13875	COG2855	membrane
H8N04_RS13895	COG3682	Transcriptional regulator
H8N04_RS13930	COG1132	(ABC) transporter
H8N04_RS13935	COG1132	(ABC) transporter
H8N04_RS13935	COG2375	cellular response to nickel ion
H8N04_RS13955	COG3620	sequence-specific DNA binding
H8N04_RS13980	COG1131	(ABC) transporter
H8N04_RS14055	COG2801	Transposase and inactivated derivatives
H8N04_RS14065	COG1846	Transcriptional regulator
H8N04_RS14110	COG1438	arginine binding
H8N04_RS14130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H8N04_RS14130	COG3711	transcriptional antiterminator
H8N04_RS14135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H8N04_RS14135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H8N04_RS14135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H8N04_RS14140	COG1482	cell wall glycoprotein biosynthetic process
H8N04_RS14150	COG3942	CHAP domain
H8N04_RS14150	COG1705	Flagellar rod assembly protein muramidase FlgJ
H8N04_RS14155	COG1535	isochorismatase
H8N04_RS14155	COG3433	isochorismatase activity
H8N04_RS14170	COG0438	transferase activity, transferring glycosyl groups
H8N04_RS14185	COG1073	alpha beta
H8N04_RS14205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H8N04_RS14225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H8N04_RS14315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H8N04_RS14390	COG0471	metal ion transport
H8N04_RS14395	COG2962	Rard protein
H8N04_RS14405	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
H8N04_RS14420	COG1136	(ABC) transporter
H8N04_RS14425	COG0577	efflux transmembrane transporter activity
H8N04_RS14435	COG1278	Cold shock
H8N04_RS14455	COG1475	DNA binding
H8N04_RS14505	COG0577	efflux transmembrane transporter activity
H8N04_RS14510	COG1136	(ABC) transporter
H8N04_RS14525	COG1131	(ABC) transporter