locus-tag	class	description
HTZ91_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HTZ91_RS00015	ENOG410848D	S4 domain protein YaaA
HTZ91_RS00035	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HTZ91_RS00060	ENOG4105DWV	Homoserine O-trans-acetylase
HTZ91_RS00070	ENOG4105BZR	domain protein
HTZ91_RS00080	ENOG4105CDU	Replicative dna helicase
HTZ91_RS00085	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HTZ91_RS00120	ENOG4105Q2H	domain protein
HTZ91_RS00125	ENOG4105CGH	5'-nucleotidase
HTZ91_RS00145	ENOG4108BUD	transposase
HTZ91_RS00155	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HTZ91_RS00160	ENOG4108ZMQ	domain protein
HTZ91_RS00165	ENOG4107RVG	penicillin-binding protein
HTZ91_RS00170	ENOG4105CCN	Peptidase M56
HTZ91_RS00225	ENOG4105CB5	ATP-dependent DNA helicase recG
HTZ91_RS00265	ENOG4105F9F	transposase
HTZ91_RS00275	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HTZ91_RS00280	ENOG4107SQC	5-methylcytosine-specific restriction enzyme subunit McrC
HTZ91_RS00325	ENOG4108YM7	Gcn5-related n-acetyltransferase
HTZ91_RS00360	ENOG4108NQ3	Phosphatidylinositol-specific phospholipase C
HTZ91_RS00380	ENOG4105C57	major facilitator superfamily
HTZ91_RS00390	ENOG4105CCI	Myosin-Cross-Reactive Antigen
HTZ91_RS00405	ENOG4106I9N	Immunoglobulin G binding protein A
HTZ91_RS00415	ENOG4108IHU	transport system permease protein
HTZ91_RS00420	ENOG4105DQ5	transport system permease protein
HTZ91_RS00425	ENOG4108MES	Periplasmic binding protein
HTZ91_RS00435	ENOG4105CIF	Ornithine Cyclodeaminase
HTZ91_RS00440	ENOG4105DJU	Siderophore biosynthesis protein
HTZ91_RS00445	ENOG4105C6X	Major Facilitator
HTZ91_RS00450	ENOG4105DBM	Siderophore biosynthesis protein
HTZ91_RS00455	ENOG4105DUU	IucA IucC family protein
HTZ91_RS00465	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HTZ91_RS00470	ENOG41067FT	ParB-like nuclease domain
HTZ91_RS00480	ENOG4105CHR	reductase
HTZ91_RS00490	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HTZ91_RS00500	ENOG4105CPK	Glycosyl transferase (Group 1
HTZ91_RS00515	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HTZ91_RS00530	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HTZ91_RS00535	ENOG4108J8C	transporter major facilitator family protein
HTZ91_RS00575	ENOG4105CGH	5'-nucleotidase
HTZ91_RS00590	ENOG4105C0A	alcohol dehydrogenase
HTZ91_RS00615	ENOG4105C5E	polysaccharide biosynthesis protein
HTZ91_RS00625	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HTZ91_RS00655	ENOG4105D3Q	Sugar transferase
HTZ91_RS00670	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HTZ91_RS00680	ENOG4105WD1	Membrane
HTZ91_RS00690	ENOG4105PGM	cation diffusion facilitator family transporter
HTZ91_RS00720	ENOG4105C1G	acyl-Coa dehydrogenase
HTZ91_RS00725	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
HTZ91_RS00775	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HTZ91_RS00780	ENOG4105D3W	isochorismatase
HTZ91_RS00785	ENOG4107RA9	decarboxylase
HTZ91_RS00815	ENOG4105QEK	Transcriptional regulator
HTZ91_RS00840	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HTZ91_RS00845	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HTZ91_RS00855	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HTZ91_RS00885	ENOG4105EG2	ABC transporter, permease
HTZ91_RS00895	ENOG4105CK5	oxidoreductase
HTZ91_RS00905	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
HTZ91_RS00910	ENOG4105CXY	transporter
HTZ91_RS00965	ENOG4105CHU	acetyl-coa acetyltransferase
HTZ91_RS00970	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HTZ91_RS00975	ENOG4105C1G	acyl-Coa dehydrogenase
HTZ91_RS00980	ENOG4105CEY	Amp-dependent synthetase and ligase
HTZ91_RS00985	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
HTZ91_RS01000	ENOG4107RRN	ABC transporter substrate-binding protein
HTZ91_RS01005	ENOG4105K78	MarR family Transcriptional regulator
HTZ91_RS01030	ENOG4105CI1	PTS System
HTZ91_RS01035	ENOG4105DU0	nucleoside hydrolase
HTZ91_RS01055	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
HTZ91_RS01060	ENOG4105DT3	PTS system, galactitol-specific IIc component
HTZ91_RS01065	ENOG4105CPQ	Dehydrogenase
HTZ91_RS01075	ENOG4105CPQ	Dehydrogenase
HTZ91_RS01085	ENOG4105EJJ	Dehydrogenase
HTZ91_RS01090	ENOG4107RZX	Teichoic acid biosynthesis protein
HTZ91_RS01095	ENOG4107SJB	teichoic acid biosynthesis
HTZ91_RS01105	ENOG4105EJJ	Dehydrogenase
HTZ91_RS01110	ENOG4107RZX	Teichoic acid biosynthesis protein
HTZ91_RS01145	ENOG4105DSQ	Nitric oxide reductase
HTZ91_RS01155	ENOG4105CI1	PTS System
HTZ91_RS01160	ENOG4105CS2	ec 3.2.1.21
HTZ91_RS01165	ENOG4105DVA	methyltransferase
HTZ91_RS01185	ENOG4105EV1	Ribose uptake protein RbsU
HTZ91_RS01220	ENOG4105DA5	(ABC) transporter
HTZ91_RS01240	ENOG4105VRS	hydrolase family 18
HTZ91_RS01355	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
HTZ91_RS01360	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
HTZ91_RS01385	ENOG4105D9N	nucleoside
HTZ91_RS01390	ENOG4107RJ1	sodium solute
HTZ91_RS01400	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
HTZ91_RS01405	ENOG4106KNT	transcriptional regulator
HTZ91_RS01440	ENOG4105DEN	Luciferase family
HTZ91_RS01465	ENOG4105CMR	udp-glucose 4-epimerase
HTZ91_RS01470	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HTZ91_RS01480	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
HTZ91_RS01485	ENOG4105CID	antiterminator
HTZ91_RS01505	ENOG4105CXY	transporter
HTZ91_RS01535	ENOG410650H	(LipO)protein
HTZ91_RS01545	ENOG4107SJW	iron permease, FTR1
HTZ91_RS01550	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HTZ91_RS01555	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HTZ91_RS01565	ENOG4105VZ8	Transcriptional regulator
HTZ91_RS01575	ENOG4105CJ1	ABC, transporter
HTZ91_RS01610	ENOG4105C28	cystathionine
HTZ91_RS01615	ENOG4105C28	cystathionine
HTZ91_RS01620	ENOG4105FA0	parb-like partition protein
HTZ91_RS01625	ENOG4105D8X	mechanosensitive ion channel
HTZ91_RS01630	ENOG4105VDK	protein, conserved in bacteria
HTZ91_RS01635	ENOG4105C3G	gtp-binding protein
HTZ91_RS01650	ENOG4108UUM	single-stranded DNA-binding protein
HTZ91_RS01745	ENOG4108TFU	terminase (Small subunit)
HTZ91_RS01825	ENOG4105D3R	alkyl hydroperoxide reductase
HTZ91_RS01835	ENOG4107R6U	sodium dicarboxylate symporter
HTZ91_RS01865	ENOG4105C2W	permease
HTZ91_RS01870	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HTZ91_RS01900	ENOG4105KA3	membrAne
HTZ91_RS02035	ENOG4105CKI	cobalamin synthesis protein
HTZ91_RS02060	ENOG4108TWJ	NADH dehydrogenase subunit 5
HTZ91_RS02070	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
HTZ91_RS02095	ENOG4105C8J	)-transporter
HTZ91_RS02105	ENOG4105C28	cystathionine
HTZ91_RS02115	ENOG4108UMI	ABC transporter, permease
HTZ91_RS02120	ENOG4105D01	(LipO)protein
HTZ91_RS02155	ENOG4105C5Q	Transcriptional regulator
HTZ91_RS02160	ENOG4105CBC	glutamate synthase
HTZ91_RS02165	ENOG4105BZ8	glutamate synthase
HTZ91_RS02175	ENOG4105C5Y	PTS System
HTZ91_RS02180	ENOG4105CG3	alpha amylase, catalytic region
HTZ91_RS02185	ENOG4107414	GntR family transcriptional regulator
HTZ91_RS02205	ENOG4105C6E	dna polymerase iii
HTZ91_RS02240	ENOG4105CXN	decarboxylase
HTZ91_RS02250	ENOG4105X0R	protein from nitrogen regulatory protein P-II
HTZ91_RS02255	ENOG4105FA2	dna polymerase iii
HTZ91_RS02260	ENOG4105MA4	psp1 domain protein
HTZ91_RS02270	ENOG41060K3	Methyltransferase
HTZ91_RS02280	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HTZ91_RS02290	ENOG4105F8V	Hydrolase, tatD family
HTZ91_RS02295	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
HTZ91_RS02305	ENOG4105W42	Veg protein
HTZ91_RS02315	ENOG4105DFT	pur operon repressor
HTZ91_RS02320	ENOG4105KME	endoribonuclease L-psp
HTZ91_RS02340	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HTZ91_RS02365	ENOG4108IY2	MazG family
HTZ91_RS02370	ENOG41082I2	s4 domain protein
HTZ91_RS02380	ENOG41060GV	RNA binding s1 domain protein
HTZ91_RS02390	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HTZ91_RS02395	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HTZ91_RS02405	ENOG4105C6T	cysteine synthase
HTZ91_RS02410	ENOG4105EEI	dihydropteroate synthase
HTZ91_RS02415	ENOG4105KRF	dihydroneopterin aldolase
HTZ91_RS02420	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HTZ91_RS02500	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HTZ91_RS02515	ENOG4105D9N	nucleoside
HTZ91_RS02525	ENOG4108Z0C	Uvrb UvrC protein
HTZ91_RS02540	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HTZ91_RS02545	ENOG4105CTP	PilT protein domain protein
HTZ91_RS02565	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HTZ91_RS02595	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HTZ91_RS02620	ENOG4107Y49	methyltransferase
HTZ91_RS02690	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HTZ91_RS02695	ENOG4105ZMH	deoxynucleoside kinase
HTZ91_RS02705	ENOG4108Z6B	deaminase
HTZ91_RS02710	ENOG410667J	hydrolase
HTZ91_RS02750	ENOG4107YEI	lmbE family
HTZ91_RS02810	ENOG4105DWF	phosphomethylpyrimidine kinase
HTZ91_RS02855	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
HTZ91_RS02860	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HTZ91_RS02880	ENOG4107QN2	dihydrolipoyl dehydrogenase
HTZ91_RS02920	ENOG4105CPC	Aldo Keto reductase
HTZ91_RS02925	ENOG4108WS4	fmn reductase
HTZ91_RS02935	ENOG4105DCI	Phosphohydrolase
HTZ91_RS02940	ENOG4108XFG	YwhD family
HTZ91_RS02970	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HTZ91_RS02985	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HTZ91_RS03025	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HTZ91_RS03065	ENOG4105EEQ	Na H antiporter
HTZ91_RS03080	ENOG4105DSE	periplasmic solute binding protein
HTZ91_RS03085	ENOG4105CC5	ABC transporter
HTZ91_RS03090	ENOG4105DIK	(ABC) transporter
HTZ91_RS03095	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
HTZ91_RS03130	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
HTZ91_RS03140	ENOG4105BZ1	(ABC) transporter
HTZ91_RS03155	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
HTZ91_RS03160	ENOG4105E0A	ABC, transporter
HTZ91_RS03165	ENOG4105DQ5	transport system permease protein
HTZ91_RS03170	ENOG4105EHG	Permease protein
HTZ91_RS03175	ENOG4105CMT	Dihydroxyacetone kinase
HTZ91_RS03195	ENOG4108K88	Membrane
HTZ91_RS03230	ENOG4105C19	ABC transporter
HTZ91_RS03240	ENOG4107GRR	phosphate transport regulator
HTZ91_RS03245	ENOG4105CJ3	phosphate transporter
HTZ91_RS03250	ENOG4105VRS	hydrolase family 18
HTZ91_RS03295	ENOG4105S8Q	sugar efflux transporter
HTZ91_RS03300	ENOG4105SXS	Protein of unknown function (DUF456)
HTZ91_RS03310	ENOG4108BUD	transposase
HTZ91_RS03355	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HTZ91_RS03365	ENOG4106PHI	plasmid recombination enzyme
HTZ91_RS03470	ENOG4105ZX1	Transposase C
HTZ91_RS03475	ENOG4108BUD	transposase
HTZ91_RS03505	ENOG4108YYQ	gCN5-related N-acetyltransferase
HTZ91_RS03510	ENOG4108URH	decarboxylase
HTZ91_RS03530	ENOG4108JJ9	ABC, transporter
HTZ91_RS03535	ENOG4108JJ8	(ABC) transporter
HTZ91_RS03540	ENOG4105K56	Transcriptional regulator
HTZ91_RS03545	ENOG4105CKI	cobalamin synthesis protein
HTZ91_RS03550	ENOG4107QM2	Aldo Keto reductase
HTZ91_RS03560	ENOG4105F9F	transposase
HTZ91_RS03565	ENOG4107QPK	)-transporter
HTZ91_RS03570	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HTZ91_RS03600	ENOG4108Z66	YbaK ebsC protein
HTZ91_RS03605	ENOG4105E98	transcriptional regulator DeoR family
HTZ91_RS03610	ENOG4105DE4	1-phosphofructokinase
HTZ91_RS03615	ENOG4105DM4	PTS System
HTZ91_RS03620	ENOG4105CE4	GlcNAc 6-P deacetylase
HTZ91_RS03625	ENOG4105C37	(CBS) domain
HTZ91_RS03635	ENOG4105CKK	Glycosyl transferase, family 2
HTZ91_RS03665	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HTZ91_RS03670	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
HTZ91_RS03680	ENOG4105DDQ	anthranilate synthase
HTZ91_RS03685	ENOG4105CRQ	synthase (Component I)
HTZ91_RS03715	ENOG4105C5H	ABC transporter
HTZ91_RS03720	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HTZ91_RS03725	ENOG4108IJ8	ABC transporter
HTZ91_RS03730	ENOG4105E90	ABC transporter
HTZ91_RS03740	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
HTZ91_RS03755	ENOG4105DUX	Transporter
HTZ91_RS03775	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HTZ91_RS03780	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HTZ91_RS03785	ENOG4105DHS	permease protein
HTZ91_RS03790	ENOG4105CM4	permease protein
HTZ91_RS03795	ENOG4108IPW	abc transporter atp-binding protein
HTZ91_RS03855	ENOG4105ESV	Glycosyl transferase, family 4
HTZ91_RS03860	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HTZ91_RS03865	ENOG4105EPR	degv family
HTZ91_RS03875	ENOG41081UC	Inherit from COG: Competence protein
HTZ91_RS03900	ENOG41068JE	domain protein
HTZ91_RS03915	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HTZ91_RS03955	ENOG4105CHW	UPF0052 protein
HTZ91_RS03970	ENOG4105C6K	Malic enzyme
HTZ91_RS03990	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HTZ91_RS04020	ENOG4105XZU	Preprotein translocase, subunit SecG
HTZ91_RS04030	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HTZ91_RS04095	ENOG4105VEQ	Cold shock protein
HTZ91_RS04135	ENOG4105CVJ	phosphoglycerate mutase
HTZ91_RS04140	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HTZ91_RS04165	ENOG4105SZ6	Thioredoxin
HTZ91_RS04170	ENOG41080E8	Transcriptional regulator, Spx MgsR family
HTZ91_RS04180	ENOG4108XI2	Domain of unknown function (DUF1963)
HTZ91_RS04200	ENOG4108UMI	ABC transporter, permease
HTZ91_RS04205	ENOG4105D01	(LipO)protein
HTZ91_RS04220	ENOG4105C3K	feS assembly ATPase SufC
HTZ91_RS04225	ENOG4105JRK	feS assembly protein SufD
HTZ91_RS04230	ENOG4105C9B	Cysteine desulfurase
HTZ91_RS04235	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HTZ91_RS04265	ENOG4105I3N	Conserved Protein
HTZ91_RS04285	ENOG4105MMD	transcriptional regulator
HTZ91_RS04325	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HTZ91_RS04335	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
HTZ91_RS04340	ENOG41083MR	nifu domain-containing protein
HTZ91_RS04360	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HTZ91_RS04370	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HTZ91_RS04380	ENOG4105KA0	thioesterase Superfamily protein
HTZ91_RS04435	ENOG41060GV	RNA binding s1 domain protein
HTZ91_RS04440	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HTZ91_RS04450	ENOG4105D82	Glutamate dehydrogenase
HTZ91_RS04455	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HTZ91_RS04520	ENOG4108KP7	hydrolase
HTZ91_RS04560	ENOG4105KIS	phospholipid-binding protein
HTZ91_RS04590	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HTZ91_RS04595	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HTZ91_RS04605	ENOG4108JQ7	(ABC) transporter
HTZ91_RS04620	ENOG4105F9F	transposase
HTZ91_RS04635	ENOG4108JQ7	(ABC) transporter
HTZ91_RS04640	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HTZ91_RS04645	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HTZ91_RS04665	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HTZ91_RS04680	ENOG4105DPN	Oligoendopeptidase f
HTZ91_RS04690	ENOG4108Z18	K06886 hemoglobin
HTZ91_RS04715	ENOG4105EMS	pseudouridine synthase
HTZ91_RS04720	ENOG4105CJW	magnesium transporter
HTZ91_RS04735	ENOG4105C02	permease
HTZ91_RS04740	ENOG4105BZG	amino acid carrier protein
HTZ91_RS04790	ENOG4107TS3	membrane protein, TerC
HTZ91_RS04805	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HTZ91_RS04820	ENOG4105XVF	Competence transcription factor
HTZ91_RS04870	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HTZ91_RS04895	ENOG4108HUF	Transporter
HTZ91_RS04905	ENOG4105YB8	TM2 domain containing protein
HTZ91_RS04910	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
HTZ91_RS04915	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HTZ91_RS04920	ENOG4105E4F	Isochorismate synthase
HTZ91_RS04930	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HTZ91_RS04935	ENOG4108IPT	Naphthoate synthase
HTZ91_RS04955	ENOG4105CHM	Aminotransferase
HTZ91_RS04960	ENOG4108TGC	Acyltransferase
HTZ91_RS04990	ENOG4108KGH	TRANSCRIPTIONal
HTZ91_RS05035	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HTZ91_RS05050	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
HTZ91_RS05090	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HTZ91_RS05095	ENOG4108JJB	ABC transporter
HTZ91_RS05100	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
HTZ91_RS05115	ENOG4105DR4	Methyltransferase
HTZ91_RS05125	ENOG4105KRI	phosphocarrier protein (HPr
HTZ91_RS05150	ENOG4107ZYR	domain protein
HTZ91_RS05170	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HTZ91_RS05185	ENOG4105CPP	Dehydrogenase, E1 component
HTZ91_RS05195	ENOG4107QN2	dihydrolipoyl dehydrogenase
HTZ91_RS05215	ENOG4105F38	ABC transporter, permease
HTZ91_RS05220	ENOG4105D38	putrescine abc transporter
HTZ91_RS05225	ENOG4107RUE	extracellular solute-binding protein family 1
HTZ91_RS05250	ENOG4105ECY	inositol monophosphatase
HTZ91_RS05260	ENOG4105CI3	gtp-binding protein typa
HTZ91_RS05280	ENOG4105CNI	cell division protein FtsW
HTZ91_RS05305	ENOG4106UY4	Inherit from COG: Scp-like extracellular
HTZ91_RS05315	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HTZ91_RS05330	ENOG4106H78	methyltransferase
HTZ91_RS05385	ENOG4105KFN	sortase, SrtB family
HTZ91_RS05400	ENOG4108RWN	rrna methyltransferase
HTZ91_RS05430	ENOG4105DCG	PHP domain protein
HTZ91_RS05440	ENOG4105K63	Thioredoxin
HTZ91_RS05455	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
HTZ91_RS05465	ENOG4105E33	succinate dehydrogenase
HTZ91_RS05565	ENOG4105DBV	ornithine carbamoyltransferase
HTZ91_RS05575	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HTZ91_RS05630	ENOG41068DC	Essential cell division protein (By similarity)
HTZ91_RS05635	ENOG4105CJN	penicillin-binding protein
HTZ91_RS05660	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HTZ91_RS05670	ENOG4105DFA	alanine racemase domain protein
HTZ91_RS05680	ENOG41067XK	integral membrane protein
HTZ91_RS05685	ENOG4105DBK	s4 domain protein
HTZ91_RS05695	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HTZ91_RS05705	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HTZ91_RS05715	ENOG4105C34	Pseudouridine synthase
HTZ91_RS05755	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HTZ91_RS05785	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HTZ91_RS05790	ENOG4105C25	Primosomal protein n'
HTZ91_RS05800	ENOG4105YB8	TM2 domain containing protein
HTZ91_RS05815	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HTZ91_RS05825	ENOG4108ZF3	Phosphatase
HTZ91_RS05840	ENOG4105DJV	ribulose-phosphate 3-epimerase
HTZ91_RS05855	ENOG4108ZAA	Alkaline-shock protein
HTZ91_RS05885	ENOG4105CHR	reductase
HTZ91_RS05900	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HTZ91_RS05905	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HTZ91_RS05945	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HTZ91_RS05970	ENOG4108RMH	femAB family
HTZ91_RS05975	ENOG4105C79	DNA protecting protein DprA
HTZ91_RS06040	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HTZ91_RS06045	ENOG4105KNE	Phosphatidate cytidylyltransferase
HTZ91_RS06070	ENOG4105CHV	Transcription elongation factor NusA
HTZ91_RS06075	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
HTZ91_RS06100	ENOG4105DTN	riboflavin biosynthesis protein ribF
HTZ91_RS06125	ENOG4105FDP	GntR family transcriptional regulator
HTZ91_RS06140	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
HTZ91_RS06155	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HTZ91_RS06160	ENOG4105CEV	competence damage-inducible protein
HTZ91_RS06180	ENOG4105D48	metallophosphoesterase
HTZ91_RS06185	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
HTZ91_RS06190	ENOG4105DQU	oxidoreductase, subunit beta
HTZ91_RS06225	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
HTZ91_RS06230	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HTZ91_RS06255	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HTZ91_RS06260	ENOG4108V06	Glutathione peroxidase
HTZ91_RS06265	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HTZ91_RS06270	ENOG4105CXI	aluminum resistance protein
HTZ91_RS06275	ENOG4105KV4	Transcriptional regulator
HTZ91_RS06290	ENOG4105F9F	transposase
HTZ91_RS06320	ENOG4106BHR	ftsk SpoIIIE family protein
HTZ91_RS06345	ENOG4106128	DNA-binding helix-turn-helix protein
HTZ91_RS06490	ENOG4108M15	ABC transporter
HTZ91_RS06505	ENOG4108S01	response regulator
HTZ91_RS06530	ENOG4105CFH	Aspartokinase
HTZ91_RS06535	ENOG4105D6E	homoserine dehydrogenase
HTZ91_RS06540	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
HTZ91_RS06565	ENOG4108IQI	permease
HTZ91_RS06605	ENOG4105VPS	UPF0291 protein
HTZ91_RS06645	ENOG4105C94	Transporter
HTZ91_RS06705	ENOG4108FKN	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HTZ91_RS06710	ENOG4108RCF	TRANSCRIPTIONal
HTZ91_RS06725	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HTZ91_RS06735	ENOG4105DER	m42 family
HTZ91_RS06740	ENOG4105CRQ	synthase (Component I)
HTZ91_RS06745	ENOG4105DDQ	anthranilate synthase
HTZ91_RS06780	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
HTZ91_RS06825	ENOG4105DPN	Oligoendopeptidase f
HTZ91_RS06830	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HTZ91_RS06840	ENOG4105E2Z	phosphate ABC transporter (Permease
HTZ91_RS06845	ENOG4105C8U	phosphate abc transporter
HTZ91_RS06860	ENOG4105C5H	ABC transporter
HTZ91_RS06865	ENOG4105CFH	Aspartokinase
HTZ91_RS06870	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HTZ91_RS06895	ENOG4108XFP	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HTZ91_RS06900	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HTZ91_RS06940	ENOG4107T89	von Willebrand factor, type A
HTZ91_RS06945	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
HTZ91_RS06975	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HTZ91_RS06990	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HTZ91_RS07010	ENOG4105F9F	transposase
HTZ91_RS07040	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HTZ91_RS07090	ENOG4107R7I	amino acid
HTZ91_RS07110	ENOG410890F	Dynamin family
HTZ91_RS07125	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HTZ91_RS07155	ENOG4105BZ4	penicillin-binding protein
HTZ91_RS07165	ENOG4105CSM	endonuclease III
HTZ91_RS07195	ENOG4105CPK	Glycosyl transferase (Group 1
HTZ91_RS07200	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
HTZ91_RS07245	ENOG4105EAH	synthase
HTZ91_RS07260	ENOG4105K70	DNA-binding protein
HTZ91_RS07295	ENOG4105HDK	L-asparaginase
HTZ91_RS07300	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
HTZ91_RS07310	ENOG4106BU8	elastin-binding protein ebpS
HTZ91_RS07315	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HTZ91_RS07355	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
HTZ91_RS07405	ENOG4108FKH	Transglycosylase SLT domain
HTZ91_RS07630	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HTZ91_RS07635	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HTZ91_RS07675	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HTZ91_RS07680	ENOG4105FE9	pseudouridine synthase
HTZ91_RS07700	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HTZ91_RS07705	ENOG4105I3K	Ferric uptake regulator, Fur family
HTZ91_RS07710	ENOG4108YZ4	nudix hydrolase
HTZ91_RS07715	ENOG4105CPC	Aldo Keto reductase
HTZ91_RS07725	ENOG4105PDP	Short chain dehydrogenase
HTZ91_RS07730	ENOG4105II7	pyrroline-5-carboxylate reductase
HTZ91_RS07740	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HTZ91_RS07790	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HTZ91_RS07800	ENOG4108QEG	Membrane
HTZ91_RS07810	ENOG4105C7S	Dehydrogenase
HTZ91_RS07815	ENOG4105CPP	Dehydrogenase, E1 component
HTZ91_RS07830	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HTZ91_RS07860	ENOG4108ZSR	alkaline shock protein
HTZ91_RS07865	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HTZ91_RS07880	ENOG4105DC7	peptidase M24
HTZ91_RS07895	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
HTZ91_RS07900	ENOG4105WZW	rhodanese family
HTZ91_RS07945	ENOG4106855	Competence protein
HTZ91_RS07950	ENOG4105D7Q	type ii secretion system
HTZ91_RS07960	ENOG4105C5X	domain protein
HTZ91_RS07985	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HTZ91_RS07995	ENOG4107RF6	penicillin-binding protein
HTZ91_RS08000	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HTZ91_RS08005	ENOG4105N80	Ferric uptake regulator, Fur family
HTZ91_RS08010	ENOG4105FAV	ABC, transporter
HTZ91_RS08015	ENOG4105FDK	ABC transporter
HTZ91_RS08025	ENOG4105C1J	atp-dependent rna helicase
HTZ91_RS08040	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HTZ91_RS08075	ENOG4105KG3	cytidine deaminase
HTZ91_RS08090	ENOG4105C9A	Phoh family
HTZ91_RS08105	ENOG4105F7J	membrane-bound serine protease
HTZ91_RS08115	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HTZ91_RS08120	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HTZ91_RS08150	ENOG4105CSA	Coproporphyrinogen iii oxidase
HTZ91_RS08165	ENOG4105TQK	DNA polymerase iii, delta' subunit
HTZ91_RS08170	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HTZ91_RS08175	ENOG4108UK2	deaminase
HTZ91_RS08185	ENOG4105DXX	methyltransferase
HTZ91_RS08190	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HTZ91_RS08195	ENOG4108WF2	Metal Dependent Phosphohydrolase
HTZ91_RS08205	ENOG410812S	Rna-binding protein
HTZ91_RS08215	ENOG4105CQW	ribosome biogenesis GTPase YqeH
HTZ91_RS08220	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HTZ91_RS08245	ENOG4105C5A	transporter
HTZ91_RS08260	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HTZ91_RS08270	ENOG4105P4J	Allophanate hydrolase, subunit 1
HTZ91_RS08285	ENOG4105CFP	Peptidase U32
HTZ91_RS08290	ENOG4105XYU	peptidase (U32 family)
HTZ91_RS08320	ENOG4105C7H	Helicase, RecD TraA family
HTZ91_RS08335	ENOG4105C3J	Cysteine desulfurase
HTZ91_RS08340	ENOG4105DEN	Luciferase family
HTZ91_RS08350	ENOG41061M1	UPF0337 protein
HTZ91_RS08360	ENOG4105D1H	recombination factor protein RarA
HTZ91_RS08365	ENOG4105CUZ	uba thif-type nad fad binding protein
HTZ91_RS08390	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HTZ91_RS08410	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HTZ91_RS08415	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HTZ91_RS08420	ENOG4105VIE	preprotein translocase, subunit YajC
HTZ91_RS08460	ENOG4105X36	(ribosomal) protein
HTZ91_RS08505	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
HTZ91_RS08510	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HTZ91_RS08520	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HTZ91_RS08540	ENOG4105D52	delta-aminolevulinic acid dehydratase
HTZ91_RS08590	ENOG4105U6W	MutT NUDIX family protein
HTZ91_RS08610	ENOG4108IQI	permease
HTZ91_RS08655	ENOG4105C2M	dna polymerase I
HTZ91_RS08665	ENOG4105BZU	Histidine kinase
HTZ91_RS08670	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HTZ91_RS08680	ENOG4105BZN	citrate synthase
HTZ91_RS08685	ENOG4105C85	amino acid
HTZ91_RS08710	ENOG4105C6K	Malic enzyme
HTZ91_RS08720	ENOG4105SFS	phosphoesterase RecJ domain protein
HTZ91_RS08775	ENOG4105EJ9	Membrane
HTZ91_RS08810	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HTZ91_RS08815	ENOG4108X3M	OsmC Ohr family protein
HTZ91_RS08820	ENOG4105C5R	Aminotransferase
HTZ91_RS08825	ENOG4108JQ1	Dehydrogenase
HTZ91_RS08845	ENOG4105F6E	Acyl-transferase
HTZ91_RS08850	ENOG4105C0H	protease
HTZ91_RS08885	ENOG4105F1V	Acetoin utilization protein
HTZ91_RS08905	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HTZ91_RS08935	ENOG4108VDD	TRNA binding domain protein
HTZ91_RS08960	ENOG4105C8F	Beta-lactamase domain protein
HTZ91_RS09000	ENOG4108V15	phosphotransferase enzyme family
HTZ91_RS09030	ENOG4105CBX	hi0933 family
HTZ91_RS09050	ENOG410605W	Major Facilitator
HTZ91_RS09055	ENOG4105N5T	Radical SAM Protein
HTZ91_RS09070	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
HTZ91_RS09095	ENOG4108R6K	riboflavin synthase, subunit alpha
HTZ91_RS09100	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HTZ91_RS09120	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
HTZ91_RS09155	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HTZ91_RS09165	ENOG4105WMR	Protein CrcB homolog
HTZ91_RS09175	ENOG4105CV8	reductase
HTZ91_RS09200	ENOG4105E09	nadh pyrophosphatase
HTZ91_RS09290	ENOG4106AM8	polysaccharide lyase family 8
HTZ91_RS09470	ENOG4105C1Q	protoporphyrinogen oxidase
HTZ91_RS09505	ENOG4105K59	histidine triad (HIT) protein
HTZ91_RS09535	ENOG4107VRP	DNA repair exonuclease
HTZ91_RS09555	ENOG4105WH1	Two component transcriptional regulator luxr family
HTZ91_RS09560	ENOG4105BZU	Histidine kinase
HTZ91_RS09565	ENOG4108YBP	pseudouridine synthase
HTZ91_RS09595	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HTZ91_RS09600	ENOG4105CDA	abc transporter atp-binding protein
HTZ91_RS09605	ENOG4105E5Q	amino acid AbC transporter
HTZ91_RS09775	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTZ91_RS09785	ENOG4107NBY	Membrane
HTZ91_RS09800	ENOG4105CEN	a g-specific adenine glycosylase
HTZ91_RS09805	ENOG41067AE	Membrane-bound metal-dependent hydrolase
HTZ91_RS09815	ENOG4105EY8	ABC transporter
HTZ91_RS09850	ENOG4108S4H	thioesterase Superfamily protein
HTZ91_RS09875	ENOG4107U9T	Pfam:Ribonuclease_BN
HTZ91_RS09885	ENOG4105ENE	Histidine kinase
HTZ91_RS09900	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HTZ91_RS10005	ENOG4105C4R	Atp-dependent dna helicase
HTZ91_RS10015	ENOG4105KGF	protein, YerC YecD
HTZ91_RS10050	ENOG4105DAP	Nicotinate phosphoribosyltransferase
HTZ91_RS10060	ENOG4105CQC	Prephenate dehydratase
HTZ91_RS10095	ENOG4105C26	Dehydrogenase
HTZ91_RS10145	ENOG4105CJ1	ABC, transporter
HTZ91_RS10160	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HTZ91_RS10225	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
HTZ91_RS10275	ENOG4105DR5	peptidase
HTZ91_RS10330	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HTZ91_RS10380	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HTZ91_RS10510	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HTZ91_RS10560	ENOG4105CZN	Potassium uptake protein
HTZ91_RS10595	ENOG4108TFU	terminase (Small subunit)
HTZ91_RS10680	ENOG4105VTR	Integrase
HTZ91_RS10755	ENOG4105BZU	Histidine kinase
HTZ91_RS10765	ENOG4105CUC	YeeE YedE family protein
HTZ91_RS10775	ENOG4105C5H	ABC transporter
HTZ91_RS10785	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HTZ91_RS10795	ENOG410801F	ribosomal-protein-alanine acetyltransferase
HTZ91_RS10800	ENOG41072GX	Peptidase M22 Glycoprotease
HTZ91_RS10805	ENOG4105K8N	protein family UPF0079, ATPase
HTZ91_RS10820	ENOG4105C7K	acetolactate synthase
HTZ91_RS10840	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HTZ91_RS10910	ENOG4105WN5	stage II sporulation protein
HTZ91_RS10915	ENOG4107SGM	protein serine threonine phosphatase
HTZ91_RS10945	ENOG4105CKV	Membrane
HTZ91_RS10990	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HTZ91_RS11020	ENOG4105VPX	protein, conserved in bacteria
HTZ91_RS11145	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HTZ91_RS11165	ENOG4107WAU	Protein tyrosine phosphatase
HTZ91_RS11170	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HTZ91_RS11175	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HTZ91_RS11195	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HTZ91_RS11215	ENOG4105D2N	Aldolase
HTZ91_RS11280	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HTZ91_RS11285	ENOG4108RMU	ferritin dps family protein
HTZ91_RS11305	ENOG4105DG6	mannose-6-phosphate isomerase
HTZ91_RS11320	ENOG4105PGM	cation diffusion facilitator family transporter
HTZ91_RS11350	ENOG4105DKW	ABC transporter
HTZ91_RS11365	ENOG4105ETD	TRANSCRIPTIONal
HTZ91_RS11395	ENOG4105C8B	TIGR00159 family
HTZ91_RS11455	ENOG4105D1F	ATP-binding protein
HTZ91_RS11475	ENOG4108UT2	hemolysin iii
HTZ91_RS11485	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
HTZ91_RS11495	ENOG4105DWD	nucleoside recognition domain protein
HTZ91_RS11500	ENOG4108U1V	ABC transporter, permease
HTZ91_RS11505	ENOG4105DQ5	transport system permease protein
HTZ91_RS11510	ENOG4108HUF	Transporter
HTZ91_RS11520	ENOG4106M28	alanine racemase domain protein
HTZ91_RS11530	ENOG4107SFI	Major Facilitator superfamily
HTZ91_RS11540	ENOG4105VBF	alkaline shock protein
HTZ91_RS11555	ENOG4105C94	Transporter
HTZ91_RS11565	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HTZ91_RS11580	ENOG4105CK1	PTS System
HTZ91_RS11585	ENOG4105VCP	PTS System
HTZ91_RS11645	ENOG4105VUF	Transcriptional regulator
HTZ91_RS11655	ENOG4106AM8	polysaccharide lyase family 8
HTZ91_RS11675	ENOG4107FQX	Alpha-acetolactate decarboxylase
HTZ91_RS11700	ENOG4105CB5	ATP-dependent DNA helicase recG
HTZ91_RS11770	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HTZ91_RS11775	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HTZ91_RS11890	ENOG4105C7N	Xanthine uracil vitamin C permease
HTZ91_RS11990	ENOG4108ZAF	Molybdopterin
HTZ91_RS11995	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
HTZ91_RS12015	ENOG4105D06	uba thif-type nad fad binding protein
HTZ91_RS12020	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HTZ91_RS12025	ENOG4105E0C	molybdate abc transporter
HTZ91_RS12030	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HTZ91_RS12045	ENOG4107ZYJ	bioY protein
HTZ91_RS12060	ENOG4105FDT	acyl-CoA dehydrogenase
HTZ91_RS12135	ENOG4105DFD	Na H antiporter
HTZ91_RS12165	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
HTZ91_RS12235	ENOG4107YBY	Hydrolase
HTZ91_RS12250	ENOG4105CI1	PTS System
HTZ91_RS12255	ENOG4108Q3X	Transcriptional regulator
HTZ91_RS12275	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HTZ91_RS12295	ENOG4105C5Q	Transcriptional regulator
HTZ91_RS12320	ENOG4108RPX	mosc domain containing protein
HTZ91_RS12325	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HTZ91_RS12340	ENOG4105RHA	ABC transporter, permease
HTZ91_RS12345	ENOG4108IUX	(ABC) transporter
HTZ91_RS12360	ENOG4105D6U	Sodium Glutamate Symporter
HTZ91_RS12370	ENOG4105D7N	magnesium and cobalt transport protein CorA
HTZ91_RS12395	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HTZ91_RS12400	ENOG4105CW7	secretion protein, HlyD family
HTZ91_RS12475	ENOG4105CJ1	ABC, transporter
HTZ91_RS12540	ENOG4105ECB	domain protein
HTZ91_RS12570	ENOG410606W	general stress protein
HTZ91_RS12645	ENOG4108IUE	nitrate reductase beta subunit
HTZ91_RS12655	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HTZ91_RS12660	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
HTZ91_RS12665	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HTZ91_RS12675	ENOG4108XSB	acetyltransferase, (GNAT) family
HTZ91_RS12680	ENOG4105TMB	Formate nitrite transporter
HTZ91_RS12695	ENOG4105DSE	periplasmic solute binding protein
HTZ91_RS12730	ENOG4105CDA	abc transporter atp-binding protein
HTZ91_RS12735	ENOG4105DRP	amino acid AbC transporter
HTZ91_RS12740	ENOG4105EAB	amino acid AbC transporter
HTZ91_RS12800	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HTZ91_RS12810	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HTZ91_RS12815	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HTZ91_RS12825	ENOG4105BZ1	(ABC) transporter
HTZ91_RS12845	ENOG4105BZW	Glycerate kinase
HTZ91_RS12855	ENOG4105C2C	drug resistance transporter, Bcr CflA
HTZ91_RS12875	ENOG4105C85	amino acid
HTZ91_RS12880	ENOG4105EEQ	Na H antiporter
HTZ91_RS12885	ENOG4105C0X	amino acid
HTZ91_RS12900	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HTZ91_RS12905	ENOG4105C57	major facilitator superfamily
HTZ91_RS12910	ENOG4105R40	Glycine betaine carnitine choline
HTZ91_RS12920	ENOG4105E90	ABC transporter
HTZ91_RS12940	ENOG4105CZ9	Domain of unknown function (DU1801)
HTZ91_RS12945	ENOG4107QTZ	amino acid
HTZ91_RS12950	ENOG4105EBR	Carboxylesterase
HTZ91_RS12955	ENOG4105F27	Major Facilitator
HTZ91_RS12960	ENOG4105C4B	ABC transporter, permease
HTZ91_RS12965	ENOG41083J0	(ABC) transporter
HTZ91_RS12970	ENOG4105CN9	Peptidase m42 family protein
HTZ91_RS12975	ENOG4105PQ4	(LipO)protein
HTZ91_RS12980	ENOG4105CBC	glutamate synthase
HTZ91_RS12995	ENOG4108S9F	abc transporter, atp-binding protein
HTZ91_RS13005	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HTZ91_RS13010	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HTZ91_RS13015	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HTZ91_RS13035	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
HTZ91_RS13040	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HTZ91_RS13045	ENOG4105CFC	Transporter
HTZ91_RS13050	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HTZ91_RS13125	ENOG4105M6F	mutator MutT protein
HTZ91_RS13165	ENOG4105CMG	Carbohydrate kinase
HTZ91_RS13170	ENOG4105G3Z	GntR family transcriptional regulator
HTZ91_RS13185	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
HTZ91_RS13195	ENOG4105DJB	Major Facilitator Superfamily
HTZ91_RS13200	ENOG4107T5V	SNARE associated Golgi
HTZ91_RS13205	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HTZ91_RS13220	ENOG4105CJ1	ABC, transporter
HTZ91_RS13235	ENOG4108K88	Membrane
HTZ91_RS13240	ENOG4105FBA	Phospholipase Carboxylesterase
HTZ91_RS13250	ENOG41090MY	MarR family Transcriptional regulator
HTZ91_RS13260	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HTZ91_RS13280	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
HTZ91_RS13285	ENOG4108Z6X	(sortase) family
HTZ91_RS13290	ENOG4108Z7F	N-acetyltransferase
HTZ91_RS13305	ENOG4105EJQ	L-serine dehydratase
HTZ91_RS13325	ENOG4108UZ3	Transporter
HTZ91_RS13365	ENOG4105CMU	LysR family (Transcriptional regulator
HTZ91_RS13375	ENOG41068JE	domain protein
HTZ91_RS13385	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
HTZ91_RS13390	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HTZ91_RS13415	ENOG4105EYF	MMPL domain protein
HTZ91_RS13470	ENOG4105FE1	phytoene synthase
HTZ91_RS13525	ENOG4105VPS	UPF0291 protein
HTZ91_RS13550	ENOG4105CHR	reductase
HTZ91_RS13575	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
HTZ91_RS13600	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HTZ91_RS13650	ENOG4107FQX	Alpha-acetolactate decarboxylase
HTZ91_RS13660	ENOG4105CUB	amino acid
HTZ91_RS13665	ENOG4108JPW	Aminotransferase
HTZ91_RS13680	ENOG4105DWT	malate dehydrogenase (quinone)
HTZ91_RS13690	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HTZ91_RS13720	ENOG4105TRT	Transcriptional regulator
HTZ91_RS13725	ENOG4105C94	Transporter
HTZ91_RS13740	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HTZ91_RS13745	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HTZ91_RS13750	ENOG4105D4T	Citrate transporter
HTZ91_RS13760	ENOG4108Z73	Siroheme synthase
HTZ91_RS13765	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HTZ91_RS13815	ENOG4105G6Z	alkaline phosphatase
HTZ91_RS13825	ENOG4108U05	Transcriptional regulator
HTZ91_RS13895	ENOG4105DM4	PTS System
HTZ91_RS13900	ENOG4105DG6	mannose-6-phosphate isomerase
HTZ91_RS13910	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
HTZ91_RS13915	ENOG4105WQI	isochorismatase
HTZ91_RS13940	ENOG4106E62	Accessory Sec system protein Asp3
HTZ91_RS13945	ENOG41089G2	accessory Sec system protein Asp2
HTZ91_RS13965	ENOG4105EW6	flavin reductase domain protein, FMN-binding
HTZ91_RS13985	ENOG4107XC4	flavin reductase domain protein, FMN-binding
HTZ91_RS13990	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HTZ91_RS14020	ENOG4107QJZ	Glycosyl transferase, family 2
HTZ91_RS14045	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HTZ91_RS14070	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HTZ91_RS14150	ENOG4107QPK	)-transporter
HTZ91_RS14155	ENOG4105FR1	rard protein
HTZ91_RS14165	ENOG4105D9G	High-affinity
HTZ91_RS14180	ENOG4105C19	ABC transporter
HTZ91_RS14210	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HTZ91_RS14215	ENOG4105VEQ	Cold shock protein
HTZ91_RS14235	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)