locus-tag	class	description
HTZ91_RS00015	COG2501	S4 domain
HTZ91_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HTZ91_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HTZ91_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HTZ91_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
HTZ91_RS00110	COG4863	YycH protein
HTZ91_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HTZ91_RS00125	COG0737	Belongs to the 5'-nucleotidase family
HTZ91_RS00155	COG0584	glycerophosphoryl diester phosphodiesterase
HTZ91_RS00160	COG2030	dehydratase
HTZ91_RS00265	COG2826	transposase and inactivated derivatives, IS30 family
HTZ91_RS00275	COG1401	restriction endodeoxyribonuclease activity
HTZ91_RS00280	COG4268	DNA restriction-modification system
HTZ91_RS00305	COG2814	Major facilitator Superfamily
HTZ91_RS00325	COG0456	acetyltransferase
HTZ91_RS00360	COG0823	Involved in the tonB-independent uptake of proteins
HTZ91_RS00375	COG1473	amidohydrolase
HTZ91_RS00385	COG1283	sodium-dependent phosphate transmembrane transporter activity
HTZ91_RS00390	COG4716	Myosin-crossreactive antigen
HTZ91_RS00400	COG1620	l-lactate permease
HTZ91_RS00415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTZ91_RS00420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTZ91_RS00425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HTZ91_RS00435	COG2423	ornithine cyclodeaminase activity
HTZ91_RS00440	COG4264	IucA IucC family
HTZ91_RS00445	COG2814	Major facilitator Superfamily
HTZ91_RS00450	COG4264	IucA IucC family
HTZ91_RS00455	COG4264	IucA IucC family
HTZ91_RS00465	COG0019	diaminopimelate decarboxylase activity
HTZ91_RS00470	COG1475	DNA binding
HTZ91_RS00490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HTZ91_RS00495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HTZ91_RS00500	COG0438	transferase activity, transferring glycosyl groups
HTZ91_RS00530	COG0813	purine-nucleoside phosphorylase activity
HTZ91_RS00535	COG2814	Major facilitator Superfamily
HTZ91_RS00555	COG3639	organic phosphonate transmembrane transporter activity
HTZ91_RS00575	COG0737	Belongs to the 5'-nucleotidase family
HTZ91_RS00590	COG1012	belongs to the aldehyde dehydrogenase family
HTZ91_RS00590	COG1454	alcohol dehydrogenase
HTZ91_RS00615	COG1086	Polysaccharide biosynthesis protein
HTZ91_RS00625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HTZ91_RS00655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HTZ91_RS00665	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HTZ91_RS00670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HTZ91_RS00680	COG2832	Protein of unknown function (DUF454)
HTZ91_RS00715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HTZ91_RS00720	COG1960	acyl-CoA dehydrogenase activity
HTZ91_RS00725	COG5609	conserved protein (DUF2294)
HTZ91_RS00775	COG1114	Component of the transport system for branched-chain amino acids
HTZ91_RS00780	COG1335	isochorismatase
HTZ91_RS00785	COG3961	Belongs to the TPP enzyme family
HTZ91_RS00815	COG1737	Transcriptional regulator
HTZ91_RS00845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HTZ91_RS00855	COG0405	Gamma-glutamyltransferase
HTZ91_RS00870	COG3842	ATPase activity
HTZ91_RS00880	COG1175	transmembrane transport
HTZ91_RS00885	COG3833	ABC-type maltose transport systems, permease component
HTZ91_RS00890	COG0673	inositol 2-dehydrogenase activity
HTZ91_RS00895	COG0673	inositol 2-dehydrogenase activity
HTZ91_RS00905	COG1755	Isoprenylcysteine carboxyl methyltransferase
HTZ91_RS00965	COG0183	Belongs to the thiolase family
HTZ91_RS00975	COG1960	acyl-CoA dehydrogenase activity
HTZ91_RS00980	COG0318	PFAM AMP-dependent synthetase and ligase
HTZ91_RS01000	COG0747	negative chemotaxis
HTZ91_RS01005	COG3189	MarR family transcriptional regulator
HTZ91_RS01030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HTZ91_RS01030	COG2190	(PTS) system
HTZ91_RS01030	COG1263	PTS System
HTZ91_RS01035	COG1957	nucleoside hydrolase
HTZ91_RS01055	COG3414	Phosphotransferase system galactitol-specific IIB component
HTZ91_RS01060	COG3775	system Galactitol-specific IIC component
HTZ91_RS01065	COG1063	alcohol dehydrogenase
HTZ91_RS01075	COG1063	alcohol dehydrogenase
HTZ91_RS01085	COG1063	alcohol dehydrogenase
HTZ91_RS01090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HTZ91_RS01095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HTZ91_RS01105	COG1063	alcohol dehydrogenase
HTZ91_RS01110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HTZ91_RS01150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTZ91_RS01155	COG2190	(PTS) system
HTZ91_RS01155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HTZ91_RS01155	COG1263	PTS System
HTZ91_RS01160	COG2723	6-phospho-beta-galactosidase activity
HTZ91_RS01165	COG2226	methyltransferase
HTZ91_RS01220	COG1131	(ABC) transporter
HTZ91_RS01240	COG1388	LysM domain
HTZ91_RS01240	COG3942	CHAP domain
HTZ91_RS01350	COG1114	Component of the transport system for branched-chain amino acids
HTZ91_RS01355	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HTZ91_RS01360	COG0577	efflux transmembrane transporter activity
HTZ91_RS01385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HTZ91_RS01390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HTZ91_RS01440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HTZ91_RS01470	COG3037	sugar-specific permease SgaT UlaA
HTZ91_RS01480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HTZ91_RS01485	COG3711	transcriptional antiterminator
HTZ91_RS01505	COG2271	Major facilitator Superfamily
HTZ91_RS01510	COG0346	lactoylglutathione lyase activity
HTZ91_RS01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HTZ91_RS01530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HTZ91_RS01535	COG2822	iron ion transport
HTZ91_RS01545	COG0672	)-iron permease
HTZ91_RS01550	COG0805	protein transport
HTZ91_RS01555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HTZ91_RS01565	COG1476	TRANSCRIPTIONal
HTZ91_RS01575	COG1131	(ABC) transporter
HTZ91_RS01605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HTZ91_RS01605	COG0646	methionine synthase
HTZ91_RS01610	COG0626	cystathionine gamma-synthase activity
HTZ91_RS01615	COG0626	cystathionine gamma-synthase activity
HTZ91_RS01620	COG1475	DNA binding
HTZ91_RS01625	COG0668	transmembrane transport
HTZ91_RS01630	COG4481	Protein conserved in bacteria
HTZ91_RS01635	COG0012	GTP binding
HTZ91_RS01745	COG5484	DNA packaging
HTZ91_RS01745	COG3728	DNA packaging
HTZ91_RS01835	COG1823	symporter activity
HTZ91_RS01865	COG2233	PERMEase
HTZ91_RS01900	COG3759	membrane
HTZ91_RS02035	COG0523	cobalamin synthesis protein
HTZ91_RS02060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HTZ91_RS02070	COG5609	conserved protein (DUF2294)
HTZ91_RS02085	COG1647	Serine aminopeptidase, S33
HTZ91_RS02095	COG0733	neurotransmitter:sodium symporter activity
HTZ91_RS02100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HTZ91_RS02105	COG0626	cystathionine gamma-synthase activity
HTZ91_RS02115	COG2011	ABC-type metal ion transport system permease component
HTZ91_RS02120	COG1464	Belongs to the NlpA lipoprotein family
HTZ91_RS02155	COG0583	DNA-binding transcription factor activity
HTZ91_RS02160	COG0070	glutamate synthase
HTZ91_RS02160	COG0067	glutamate synthase
HTZ91_RS02160	COG0069	glutamate synthase activity
HTZ91_RS02165	COG0493	'glutamate synthase
HTZ91_RS02175	COG1263	PTS System
HTZ91_RS02175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HTZ91_RS02180	COG0366	Alpha amylase catalytic
HTZ91_RS02185	COG2188	Transcriptional regulator
HTZ91_RS02205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HTZ91_RS02240	COG1982	Orn Lys Arg decarboxylase major
HTZ91_RS02250	COG3870	Protein conserved in bacteria
HTZ91_RS02255	COG0470	DNA polymerase III
HTZ91_RS02260	COG1774	PSP1 C-terminal conserved region
HTZ91_RS02270	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HTZ91_RS02280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HTZ91_RS02290	COG0084	hydrolase, TatD family'
HTZ91_RS02295	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HTZ91_RS02305	COG4466	Protein conserved in bacteria
HTZ91_RS02315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HTZ91_RS02320	COG0251	oxidation-reduction process
HTZ91_RS02360	COG2244	polysaccharide biosynthetic process
HTZ91_RS02365	COG3956	TIGRFAM MazG family protein
HTZ91_RS02370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HTZ91_RS02380	COG1098	S1 RNA binding domain
HTZ91_RS02395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HTZ91_RS02420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HTZ91_RS02500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTZ91_RS02515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HTZ91_RS02525	COG3880	PFAM UvrB UvrC protein
HTZ91_RS02540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HTZ91_RS02545	COG4956	integral membrane protein (PIN domain superfamily)
HTZ91_RS02565	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HTZ91_RS02620	COG2813	Specifically methylates the guanine in position
HTZ91_RS02660	COG1473	amidohydrolase
HTZ91_RS02690	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HTZ91_RS02695	COG1428	Deoxynucleoside kinase
HTZ91_RS02700	COG1428	Deoxynucleoside kinase
HTZ91_RS02710	COG0561	phosphatase activity
HTZ91_RS02750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HTZ91_RS02855	COG0095	Lipoate-protein ligase
HTZ91_RS02860	COG0083	homoserine kinase activity
HTZ91_RS02880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HTZ91_RS02920	COG0667	Aldo Keto reductase
HTZ91_RS02925	COG0655	NAD(P)H dehydrogenase (quinone) activity
HTZ91_RS02935	COG1078	dGTPase activity
HTZ91_RS02970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HTZ91_RS02975	COG4139	cobalamin transport
HTZ91_RS03080	COG0803	Belongs to the bacterial solute-binding protein 9 family
HTZ91_RS03085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HTZ91_RS03090	COG1121	(ABC) transporter
HTZ91_RS03095	COG1321	iron dependent repressor
HTZ91_RS03115	COG1682	transport, permease protein
HTZ91_RS03120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HTZ91_RS03130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HTZ91_RS03135	COG1686	Belongs to the peptidase S11 family
HTZ91_RS03140	COG1132	(ABC) transporter
HTZ91_RS03145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HTZ91_RS03155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HTZ91_RS03160	COG1120	ATPase activity
HTZ91_RS03165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTZ91_RS03170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTZ91_RS03175	COG2376	Dihydroxyacetone kinase
HTZ91_RS03195	COG3949	Membrane
HTZ91_RS03215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HTZ91_RS03230	COG1136	(ABC) transporter
HTZ91_RS03235	COG0577	efflux transmembrane transporter activity
HTZ91_RS03240	COG1392	Phosphate transport regulator
HTZ91_RS03245	COG0306	phosphate transporter
HTZ91_RS03250	COG3942	CHAP domain
HTZ91_RS03250	COG1388	LysM domain
HTZ91_RS03290	COG0583	DNA-binding transcription factor activity
HTZ91_RS03295	COG2814	Major facilitator Superfamily
HTZ91_RS03300	COG2839	Protein conserved in bacteria
HTZ91_RS03355	COG1136	(ABC) transporter
HTZ91_RS03355	COG0577	efflux transmembrane transporter activity
HTZ91_RS03430	COG0583	DNA-binding transcription factor activity
HTZ91_RS03510	COG1611	Belongs to the LOG family
HTZ91_RS03530	COG4988	ABC transporter
HTZ91_RS03535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HTZ91_RS03545	COG0523	cobalamin synthesis protein
HTZ91_RS03550	COG4989	oxidoreductase activity
HTZ91_RS03560	COG2826	transposase and inactivated derivatives, IS30 family
HTZ91_RS03565	COG0471	metal ion transport
HTZ91_RS03600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HTZ91_RS03605	COG1349	DNA-binding transcription factor activity
HTZ91_RS03610	COG1105	Belongs to the carbohydrate kinase PfkB family
HTZ91_RS03615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HTZ91_RS03615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HTZ91_RS03615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HTZ91_RS03620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HTZ91_RS03625	COG1253	flavin adenine dinucleotide binding
HTZ91_RS03630	COG0656	L-ascorbic acid biosynthetic process
HTZ91_RS03635	COG0463	Glycosyl transferase, family 2
HTZ91_RS03670	COG0720	synthase
HTZ91_RS03680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HTZ91_RS03680	COG0512	Glutamine amidotransferase of anthranilate synthase
HTZ91_RS03685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HTZ91_RS03715	COG0488	(ABC) transporter
HTZ91_RS03720	COG0514	ATP-dependent DNA helicase (RecQ)
HTZ91_RS03725	COG1125	glycine betaine transport
HTZ91_RS03725	COG0517	IMP dehydrogenase activity
HTZ91_RS03730	COG1174	glycine betaine transport
HTZ91_RS03755	COG3104	oligopeptide transport
HTZ91_RS03775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HTZ91_RS03780	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HTZ91_RS03785	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTZ91_RS03790	COG4605	iron ion homeostasis
HTZ91_RS03795	COG4604	ABC transporter, ATP-binding protein
HTZ91_RS03800	COG4607	ABC-type enterochelin transport system periplasmic component
HTZ91_RS03855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HTZ91_RS03860	COG1739	Uncharacterized protein family UPF0029
HTZ91_RS03870	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HTZ91_RS03875	COG1040	competence protein
HTZ91_RS03900	COG3942	CHAP domain
HTZ91_RS03900	COG1388	LysM domain
HTZ91_RS03955	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HTZ91_RS03970	COG0281	malic enzyme
HTZ91_RS04020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HTZ91_RS04025	COG1647	Serine aminopeptidase, S33
HTZ91_RS04030	COG0557	exoribonuclease II activity
HTZ91_RS04095	COG1278	Cold shock
HTZ91_RS04135	COG0406	alpha-ribazole phosphatase activity
HTZ91_RS04140	COG1279	arginine transmembrane transporter activity
HTZ91_RS04165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HTZ91_RS04170	COG1393	Belongs to the ArsC family
HTZ91_RS04180	COG3878	Protein conserved in bacteria
HTZ91_RS04200	COG2011	ABC-type metal ion transport system permease component
HTZ91_RS04205	COG1464	Belongs to the NlpA lipoprotein family
HTZ91_RS04220	COG0396	ATPase activity
HTZ91_RS04225	COG0719	Fe-S assembly protein
HTZ91_RS04235	COG0822	iron-sulfur transferase activity
HTZ91_RS04255	COG1253	flavin adenine dinucleotide binding
HTZ91_RS04265	COG1801	Protein of unknown function DUF72
HTZ91_RS04270	COG0730	response to heat
HTZ91_RS04285	COG4470	Protein conserved in bacteria
HTZ91_RS04295	COG2445	Protein of unknown function DUF86
HTZ91_RS04325	COG1696	Membrane protein involved in D-alanine export
HTZ91_RS04335	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HTZ91_RS04340	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HTZ91_RS04345	COG4837	Protein of unknown function (DUF1462)
HTZ91_RS04350	COG1252	NADH dehydrogenase
HTZ91_RS04360	COG0316	Belongs to the HesB IscA family
HTZ91_RS04370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HTZ91_RS04375	COG2056	Na+-H+ antiporter family
HTZ91_RS04380	COG2050	protein possibly involved in aromatic compounds catabolism
HTZ91_RS04435	COG1098	S1 RNA binding domain
HTZ91_RS04440	COG1902	pentaerythritol trinitrate reductase activity
HTZ91_RS04455	COG0584	glycerophosphoryl diester phosphodiesterase
HTZ91_RS04475	COG0398	Pfam SNARE associated Golgi protein
HTZ91_RS04520	COG0561	phosphatase activity
HTZ91_RS04545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HTZ91_RS04560	COG1881	PFAM PEBP family protein
HTZ91_RS04590	COG0601	transmembrane transport
HTZ91_RS04595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HTZ91_RS04600	COG0444	Belongs to the ABC transporter superfamily
HTZ91_RS04605	COG4608	Belongs to the ABC transporter superfamily
HTZ91_RS04610	COG4166	transmembrane transport
HTZ91_RS04620	COG2826	transposase and inactivated derivatives, IS30 family
HTZ91_RS04630	COG0444	Belongs to the ABC transporter superfamily
HTZ91_RS04635	COG4608	Belongs to the ABC transporter superfamily
HTZ91_RS04645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HTZ91_RS04680	COG1164	Oligoendopeptidase f
HTZ91_RS04690	COG2346	COG2346, Truncated hemoglobins
HTZ91_RS04705	COG2357	RelA SpoT domain protein
HTZ91_RS04715	COG0564	pseudouridine synthase activity
HTZ91_RS04720	COG2239	Acts as a magnesium transporter
HTZ91_RS04725	COG0475	glutathione-regulated potassium exporter activity
HTZ91_RS04725	COG0569	domain protein
HTZ91_RS04735	COG0628	permease
HTZ91_RS04740	COG1115	amino acid carrier protein
HTZ91_RS04790	COG0861	Integral membrane protein TerC family
HTZ91_RS04800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HTZ91_RS04805	COG0737	Belongs to the 5'-nucleotidase family
HTZ91_RS04820	COG4903	ComK protein
HTZ91_RS04835	COG4873	Protein conserved in bacteria
HTZ91_RS04895	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HTZ91_RS04905	COG2314	TM2 domain
HTZ91_RS04910	COG0456	acetyltransferase
HTZ91_RS04915	COG1575	Belongs to the MenA family. Type 1 subfamily
HTZ91_RS04920	COG1169	isochorismate synthase
HTZ91_RS04930	COG2267	carboxylic ester hydrolase activity
HTZ91_RS04955	COG0436	Aminotransferase
HTZ91_RS04960	COG3594	Acyltransferase
HTZ91_RS04990	COG1316	TRANSCRIPTIONal
HTZ91_RS05035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HTZ91_RS05050	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HTZ91_RS05090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HTZ91_RS05095	COG4172	Belongs to the ABC transporter superfamily
HTZ91_RS05100	COG4721	ABC-type cobalt transport system, permease component
HTZ91_RS05115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HTZ91_RS05140	COG1271	oxidase subunit
HTZ91_RS05145	COG1294	oxidase, subunit
HTZ91_RS05150	COG0569	domain protein
HTZ91_RS05215	COG1176	ABC-type spermidine putrescine transport system, permease component I
HTZ91_RS05220	COG1177	transmembrane transport
HTZ91_RS05225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HTZ91_RS05250	COG0483	inositol monophosphate 1-phosphatase activity
HTZ91_RS05270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HTZ91_RS05280	COG0772	Belongs to the SEDS family
HTZ91_RS05305	COG2340	Cysteine-rich secretory protein family
HTZ91_RS05310	COG3679	Belongs to the UPF0342 family
HTZ91_RS05315	COG0584	glycerophosphoryl diester phosphodiesterase
HTZ91_RS05330	COG0742	ribosomal rna small subunit methyltransferase
HTZ91_RS05385	COG4509	Sortase family
HTZ91_RS05400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HTZ91_RS05430	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HTZ91_RS05430	COG1796	DNA polymerase
HTZ91_RS05455	COG2009	succinate dehydrogenase
HTZ91_RS05460	COG1053	succinate dehydrogenase
HTZ91_RS05465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HTZ91_RS05575	COG1288	antiporter activity
HTZ91_RS05605	COG1011	Hydrolase
HTZ91_RS05630	COG4839	cell division protein FtsL
HTZ91_RS05670	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HTZ91_RS05680	COG0762	integral membrane protein
HTZ91_RS05685	COG2302	S4 RNA-binding domain
HTZ91_RS05690	COG3599	regulation of cell shape
HTZ91_RS05705	COG2514	catechol 2,3-dioxygenase activity
HTZ91_RS05715	COG0564	pseudouridine synthase activity
HTZ91_RS05725	COG2233	PERMEase
HTZ91_RS05770	COG1293	RNA-binding protein homologous to eukaryotic snRNP
HTZ91_RS05785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HTZ91_RS05790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HTZ91_RS05800	COG2314	TM2 domain
HTZ91_RS05815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HTZ91_RS05815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HTZ91_RS05825	COG0631	protein serine/threonine phosphatase activity
HTZ91_RS05840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HTZ91_RS05855	COG1302	Protein conserved in bacteria
HTZ91_RS05900	COG1196	nuclear chromosome segregation
HTZ91_RS05905	COG0552	protein localization to endoplasmic reticulum
HTZ91_RS05915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HTZ91_RS05970	COG2348	transferase activity, transferring amino-acyl groups
HTZ91_RS05975	COG0758	DNA mediated transformation
HTZ91_RS06070	COG0195	Participates in both transcription termination and antitermination
HTZ91_RS06075	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HTZ91_RS06100	COG0196	riboflavin kinase activity
HTZ91_RS06125	COG2188	Transcriptional regulator
HTZ91_RS06130	COG0612	Peptidase, M16
HTZ91_RS06135	COG0612	Peptidase, M16
HTZ91_RS06140	COG0300	oxidoreductase activity
HTZ91_RS06160	COG1058	Belongs to the CinA family
HTZ91_RS06160	COG1546	Belongs to the CinA family
HTZ91_RS06180	COG1692	metallophosphoesterase
HTZ91_RS06185	COG0674	pyruvate-flavodoxin oxidoreductase activity
HTZ91_RS06185	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HTZ91_RS06190	COG1013	pyruvate-flavodoxin oxidoreductase activity
HTZ91_RS06225	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HTZ91_RS06230	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HTZ91_RS06255	COG1923	regulation of RNA biosynthetic process
HTZ91_RS06270	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HTZ91_RS06275	COG0789	Transcriptional regulator
HTZ91_RS06290	COG2826	transposase and inactivated derivatives, IS30 family
HTZ91_RS06320	COG1674	ftsk spoiiie
HTZ91_RS06325	COG0433	COG0433 Predicted ATPase
HTZ91_RS06345	COG2946	Replication initiation factor
HTZ91_RS06490	COG1131	(ABC) transporter
HTZ91_RS06505	COG2197	response regulator
HTZ91_RS06515	COG1525	nuclease
HTZ91_RS06530	COG0527	aspartate kinase activity
HTZ91_RS06535	COG0460	homoserine dehydrogenase
HTZ91_RS06540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HTZ91_RS06565	COG0833	amino acid
HTZ91_RS06625	COG4846	Membrane protein involved in cytochrome C biogenesis
HTZ91_RS06645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTZ91_RS06655	COG0824	Thioesterase
HTZ91_RS06680	COG1115	amino acid carrier protein
HTZ91_RS06695	COG0628	permease
HTZ91_RS06725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HTZ91_RS06735	COG1363	Peptidase, m42
HTZ91_RS06740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HTZ91_RS06745	COG0512	Glutamine amidotransferase of anthranilate synthase
HTZ91_RS06830	COG0704	Plays a role in the regulation of phosphate uptake
HTZ91_RS06840	COG0581	inorganic phosphate transmembrane transporter activity
HTZ91_RS06845	COG0573	inorganic phosphate transmembrane transporter activity
HTZ91_RS06860	COG0488	(ABC) transporter
HTZ91_RS06865	COG0527	aspartate kinase activity
HTZ91_RS06870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HTZ91_RS06940	COG4548	von Willebrand factor, type A
HTZ91_RS06945	COG0714	Associated with various cellular activities
HTZ91_RS06990	COG0671	phosphoesterase, PA-phosphatase related
HTZ91_RS07010	COG2826	transposase and inactivated derivatives, IS30 family
HTZ91_RS07070	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HTZ91_RS07090	COG0531	amino acid
HTZ91_RS07105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HTZ91_RS07110	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HTZ91_RS07125	COG0116	Belongs to the methyltransferase superfamily
HTZ91_RS07155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HTZ91_RS07155	COG4499	WXG100 protein secretion system (Wss), protein YukC
HTZ91_RS07165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HTZ91_RS07170	COG3935	DnaD domain protein
HTZ91_RS07195	COG0438	transferase activity, transferring glycosyl groups
HTZ91_RS07200	COG1694	Mazg nucleotide pyrophosphohydrolase
HTZ91_RS07205	COG2738	Putative neutral zinc metallopeptidase
HTZ91_RS07210	COG4347	Protein of unknown function (DUF1405)
HTZ91_RS07245	COG0142	geranyltranstransferase activity
HTZ91_RS07300	COG0492	ferredoxin-NADP+ reductase activity
HTZ91_RS07315	COG0514	ATP-dependent DNA helicase (RecQ)
HTZ91_RS07325	COG1141	Ferredoxin
HTZ91_RS07355	COG1388	LysM domain
HTZ91_RS07355	COG0860	N-Acetylmuramoyl-L-alanine amidase
HTZ91_RS07405	COG3953	SLT domain
HTZ91_RS07405	COG5280	Phage tail tape measure protein TP901
HTZ91_RS07635	COG2176	DNA-directed DNA polymerase activity
HTZ91_RS07655	COG0582	viral genome integration into host DNA
HTZ91_RS07675	COG0745	RESPONSE REGULATOR receiver
HTZ91_RS07680	COG1187	pseudouridine synthase activity
HTZ91_RS07705	COG0735	belongs to the Fur family
HTZ91_RS07710	COG0494	nUDIX hydrolase
HTZ91_RS07715	COG0667	Aldo Keto reductase
HTZ91_RS07725	COG4221	oxidoreductase activity
HTZ91_RS07740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HTZ91_RS07750	COG0366	Alpha amylase catalytic
HTZ91_RS07755	COG1609	Transcriptional regulator
HTZ91_RS07790	COG2195	Cleaves the N-terminal amino acid of tripeptides
HTZ91_RS07800	COG4129	membrane
HTZ91_RS07810	COG0508	dehydrogenase complex catalyzes the overall conversion of
HTZ91_RS07815	COG0022	dehydrogenase e1 component
HTZ91_RS07820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HTZ91_RS07825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HTZ91_RS07830	COG0497	DNA recombination
HTZ91_RS07860	COG1302	Protein conserved in bacteria
HTZ91_RS07865	COG0439	Biotin carboxylase
HTZ91_RS07870	COG0511	ligase activity, forming carbon-carbon bonds
HTZ91_RS07880	COG0006	proline dipeptidase activity
HTZ91_RS07895	COG0095	Lipoate-protein ligase
HTZ91_RS07900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HTZ91_RS07945	COG4537	Required for transformation and DNA binding
HTZ91_RS07950	COG1459	type II secretion system
HTZ91_RS07955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HTZ91_RS07960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HTZ91_RS07965	COG0011	TIGRFAM Protein of
HTZ91_RS07970	COG1940	carbohydrate kinase activity
HTZ91_RS07975	COG4483	Protein conserved in bacteria
HTZ91_RS07985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HTZ91_RS08010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HTZ91_RS08015	COG1121	(ABC) transporter
HTZ91_RS08025	COG0513	Belongs to the DEAD box helicase family
HTZ91_RS08035	COG2384	SAM-dependent methyltransferase
HTZ91_RS08055	COG0517	IMP dehydrogenase activity
HTZ91_RS08075	COG0295	cytidine deaminase activity
HTZ91_RS08090	COG1702	phosphate starvation-inducible protein PhoH
HTZ91_RS08105	COG1030	water channel activity
HTZ91_RS08115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HTZ91_RS08120	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HTZ91_RS08150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HTZ91_RS08165	COG1466	dna polymerase III delta subunit
HTZ91_RS08170	COG2333	competence protein COMEC
HTZ91_RS08170	COG0658	competence protein
HTZ91_RS08175	COG2131	deaminase
HTZ91_RS08185	COG2226	methyltransferase
HTZ91_RS08190	COG0799	negative regulation of ribosome biogenesis
HTZ91_RS08195	COG1713	HD superfamily hydrolase involved in NAD metabolism
HTZ91_RS08205	COG1534	Rna-binding protein
HTZ91_RS08215	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HTZ91_RS08220	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HTZ91_RS08245	COG1914	H( )-stimulated, divalent metal cation uptake system
HTZ91_RS08260	COG0511	ligase activity, forming carbon-carbon bonds
HTZ91_RS08265	COG1984	allophanate hydrolase subunit 2
HTZ91_RS08270	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HTZ91_RS08320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HTZ91_RS08335	COG1104	cysteine desulfurase activity
HTZ91_RS08340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HTZ91_RS08350	COG3237	CsbD-like
HTZ91_RS08355	COG1959	2 iron, 2 sulfur cluster binding
HTZ91_RS08360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HTZ91_RS08365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HTZ91_RS08410	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HTZ91_RS08410	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HTZ91_RS08415	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HTZ91_RS08415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HTZ91_RS08420	COG1862	Preprotein translocase
HTZ91_RS08460	COG2868	ribosomal protein
HTZ91_RS08505	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HTZ91_RS08510	COG0285	dihydrofolate synthase activity
HTZ91_RS08520	COG2818	Glycosylase
HTZ91_RS08555	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HTZ91_RS08590	COG4112	unkown
HTZ91_RS08610	COG0833	amino acid
HTZ91_RS08625	COG1484	DNA-dependent DNA replication
HTZ91_RS08655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HTZ91_RS08655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HTZ91_RS08665	COG5002	protein histidine kinase activity
HTZ91_RS08670	COG0745	RESPONSE REGULATOR receiver
HTZ91_RS08680	COG0372	Belongs to the citrate synthase family
HTZ91_RS08685	COG1113	amino acid transport
HTZ91_RS08710	COG0281	malic enzyme
HTZ91_RS08720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HTZ91_RS08725	COG4109	DRTGG domain
HTZ91_RS08765	COG0827	DNA restriction-modification system
HTZ91_RS08775	COG0730	response to heat
HTZ91_RS08785	COG1104	cysteine desulfurase activity
HTZ91_RS08800	COG1956	GAF domain-containing protein
HTZ91_RS08810	COG0584	glycerophosphoryl diester phosphodiesterase
HTZ91_RS08815	COG1764	response to oxidative stress
HTZ91_RS08820	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HTZ91_RS08825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HTZ91_RS08840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HTZ91_RS08840	COG1263	PTS System
HTZ91_RS08845	COG0204	Acyl-transferase
HTZ91_RS08850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HTZ91_RS08880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HTZ91_RS08885	COG0454	-acetyltransferase
HTZ91_RS08905	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HTZ91_RS08905	COG1605	Chorismate mutase
HTZ91_RS08930	COG1674	ftsk spoiiie
HTZ91_RS08935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HTZ91_RS08945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HTZ91_RS08950	COG1363	Peptidase, m42
HTZ91_RS08960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HTZ91_RS08980	COG3682	Transcriptional regulator
HTZ91_RS09000	COG0510	thiamine kinase activity
HTZ91_RS09020	COG1187	pseudouridine synthase activity
HTZ91_RS09025	COG2244	polysaccharide biosynthetic process
HTZ91_RS09030	COG2081	HI0933 family
HTZ91_RS09050	COG2814	Major facilitator Superfamily
HTZ91_RS09055	COG1242	4 iron, 4 sulfur cluster binding
HTZ91_RS09060	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HTZ91_RS09070	COG2267	carboxylic ester hydrolase activity
HTZ91_RS09100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HTZ91_RS09100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HTZ91_RS09120	COG4193	domain, Protein
HTZ91_RS09120	COG3266	domain, Protein
HTZ91_RS09120	COG5632	N-Acetylmuramoyl-L-alanine amidase
HTZ91_RS09155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HTZ91_RS09175	COG0656	L-ascorbic acid biosynthetic process
HTZ91_RS09195	COG1506	peptidase
HTZ91_RS09200	COG2816	NAD+ diphosphatase activity
HTZ91_RS09290	COG5492	domain, Protein
HTZ91_RS09500	COG1131	(ABC) transporter
HTZ91_RS09505	COG0537	adenosine 5'-monophosphoramidase activity
HTZ91_RS09535	COG0420	3'-5' exonuclease activity
HTZ91_RS09555	COG2197	response regulator
HTZ91_RS09560	COG2203	Gaf domain
HTZ91_RS09560	COG4585	Histidine kinase
HTZ91_RS09565	COG0564	pseudouridine synthase activity
HTZ91_RS09595	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HTZ91_RS09600	COG1126	abc transporter atp-binding protein
HTZ91_RS09605	COG0765	amino acid transport
HTZ91_RS09775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTZ91_RS09785	COG4129	membrane
HTZ91_RS09800	COG1194	a g-specific adenine glycosylase
HTZ91_RS09805	COG1988	membrane-bound metal-dependent
HTZ91_RS09815	COG1134	teichoic acid transport
HTZ91_RS09815	COG1388	LysM domain
HTZ91_RS09845	COG0535	radical SAM domain protein
HTZ91_RS09850	COG1607	acyl-coa hydrolase
HTZ91_RS09855	COG2309	aminopeptidase activity
HTZ91_RS09875	COG1295	ribonuclease BN
HTZ91_RS09995	COG4851	CamS sex pheromone cAM373 precursor
HTZ91_RS10015	COG4496	protein, YerC YecD
HTZ91_RS10050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HTZ91_RS10060	COG0077	Prephenate dehydratase
HTZ91_RS10080	COG1335	isochorismatase
HTZ91_RS10095	COG1012	belongs to the aldehyde dehydrogenase family
HTZ91_RS10145	COG1131	(ABC) transporter
HTZ91_RS10160	COG1725	Transcriptional regulator
HTZ91_RS10225	COG1388	LysM domain
HTZ91_RS10225	COG5632	N-Acetylmuramoyl-L-alanine amidase
HTZ91_RS10275	COG0739	heme binding
HTZ91_RS10330	COG0740	serine-type endopeptidase activity
HTZ91_RS10510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HTZ91_RS10560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HTZ91_RS10595	COG3728	DNA packaging
HTZ91_RS10595	COG5484	DNA packaging
HTZ91_RS10680	COG0582	viral genome integration into host DNA
HTZ91_RS10740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HTZ91_RS10745	COG1621	beta-fructofuranosidase activity
HTZ91_RS10750	COG1609	Transcriptional regulator
HTZ91_RS10755	COG0004	ammonium transporteR
HTZ91_RS10760	COG0425	Belongs to the sulfur carrier protein TusA family
HTZ91_RS10765	COG2391	methyltransferase activity
HTZ91_RS10775	COG0488	(ABC) transporter
HTZ91_RS10785	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HTZ91_RS10795	COG0456	acetyltransferase
HTZ91_RS10800	COG1214	PFAM Peptidase M22, glycoprotease
HTZ91_RS10805	COG0802	atpase or kinase
HTZ91_RS10820	COG0028	Belongs to the TPP enzyme family
HTZ91_RS10895	COG2183	response to ionizing radiation
HTZ91_RS10900	COG1191	sigma factor activity
HTZ91_RS10910	COG1366	Belongs to the anti-sigma-factor antagonist family
HTZ91_RS10915	COG2208	phosphoserine phosphatase activity
HTZ91_RS10945	COG3428	Bacterial PH domain
HTZ91_RS10975	COG2205	protein histidine kinase activity
HTZ91_RS10980	COG0745	RESPONSE REGULATOR receiver
HTZ91_RS10990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HTZ91_RS11000	COG0772	Belongs to the SEDS family
HTZ91_RS11020	COG1937	Protein conserved in bacteria
HTZ91_RS11030	COG1418	mRNA catabolic process
HTZ91_RS11070	COG0629	single-stranded DNA binding
HTZ91_RS11145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HTZ91_RS11170	COG0009	L-threonylcarbamoyladenylate synthase
HTZ91_RS11175	COG2890	protein-(glutamine-N5) methyltransferase activity
HTZ91_RS11195	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HTZ91_RS11235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HTZ91_RS11280	COG0813	purine-nucleoside phosphorylase activity
HTZ91_RS11285	COG0783	Belongs to the Dps family
HTZ91_RS11305	COG1482	cell wall glycoprotein biosynthetic process
HTZ91_RS11310	COG0702	epimerase
HTZ91_RS11315	COG0640	Transcriptional regulator
HTZ91_RS11345	COG0561	phosphatase activity
HTZ91_RS11350	COG1119	ATPase activity
HTZ91_RS11365	COG3711	transcriptional antiterminator
HTZ91_RS11395	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HTZ91_RS11455	COG0489	protein tyrosine kinase activity
HTZ91_RS11475	COG1272	protein, Hemolysin III
HTZ91_RS11485	COG1988	membrane-bound metal-dependent
HTZ91_RS11500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTZ91_RS11505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTZ91_RS11510	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HTZ91_RS11520	COG3457	Alanine racemase
HTZ91_RS11525	COG4264	IucA IucC family
HTZ91_RS11530	COG2814	Major facilitator Superfamily
HTZ91_RS11555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTZ91_RS11565	COG2130	NADP-dependent
HTZ91_RS11640	COG0656	L-ascorbic acid biosynthetic process
HTZ91_RS11645	COG0789	Transcriptional regulator
HTZ91_RS11655	COG5492	domain, Protein
HTZ91_RS11675	COG3527	Alpha-acetolactate decarboxylase
HTZ91_RS11680	COG0028	Belongs to the TPP enzyme family
HTZ91_RS11775	COG0201	protein transport
HTZ91_RS11890	COG2252	PERMEase
HTZ91_RS11935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HTZ91_RS11995	COG1763	Mo-molybdopterin cofactor biosynthetic process
HTZ91_RS12015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HTZ91_RS12020	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HTZ91_RS12025	COG4149	molybdate abc transporter
HTZ91_RS12030	COG0725	ABC transporter, periplasmic molybdate-binding protein
HTZ91_RS12045	COG1268	BioY protein
HTZ91_RS12060	COG1960	acyl-CoA dehydrogenase activity
HTZ91_RS12065	COG4413	Urea transporter
HTZ91_RS12135	COG1757	Na H antiporter
HTZ91_RS12150	COG3942	CHAP domain
HTZ91_RS12215	COG1113	amino acid transport
HTZ91_RS12235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HTZ91_RS12250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HTZ91_RS12250	COG1263	PTS System
HTZ91_RS12255	COG1737	Transcriptional regulator
HTZ91_RS12275	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ91_RS12295	COG0583	DNA-binding transcription factor activity
HTZ91_RS12320	COG2258	MOSC domain
HTZ91_RS12340	COG1668	transmembrane transport
HTZ91_RS12345	COG4152	abc transporter atp-binding protein
HTZ91_RS12360	COG0786	glutamate:sodium symporter activity
HTZ91_RS12370	COG0598	Magnesium transport protein CorA
HTZ91_RS12385	COG0657	acetylesterase activity
HTZ91_RS12395	COG2814	Major facilitator Superfamily
HTZ91_RS12400	COG1566	PFAM secretion protein HlyD family protein
HTZ91_RS12415	COG2814	Major facilitator Superfamily
HTZ91_RS12475	COG1131	(ABC) transporter
HTZ91_RS12490	COG1620	l-lactate permease
HTZ91_RS12510	COG0604	alcohol dehydrogenase
HTZ91_RS12540	COG1511	domain protein
HTZ91_RS12555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HTZ91_RS12555	COG1263	PTS System
HTZ91_RS12570	COG3871	stress protein (general stress protein 26)
HTZ91_RS12635	COG2181	nitrate reductase activity
HTZ91_RS12645	COG1140	nitrate reductase beta subunit
HTZ91_RS12650	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HTZ91_RS12660	COG2146	nitrite reductase [NAD(P)H] activity
HTZ91_RS12665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HTZ91_RS12675	COG0454	-acetyltransferase
HTZ91_RS12680	COG2116	formate transmembrane transporter activity
HTZ91_RS12695	COG3443	Belongs to the bacterial solute-binding protein 9 family
HTZ91_RS12695	COG0803	Belongs to the bacterial solute-binding protein 9 family
HTZ91_RS12730	COG1126	abc transporter atp-binding protein
HTZ91_RS12735	COG0765	amino acid transport
HTZ91_RS12740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HTZ91_RS12745	COG2814	Major facilitator Superfamily
HTZ91_RS12760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HTZ91_RS12800	COG0156	8-amino-7-oxononanoate synthase activity
HTZ91_RS12810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HTZ91_RS12815	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HTZ91_RS12825	COG1132	(ABC) transporter
HTZ91_RS12845	COG1929	Belongs to the glycerate kinase type-1 family
HTZ91_RS12855	COG2814	Major facilitator Superfamily
HTZ91_RS12875	COG1113	amino acid transport
HTZ91_RS12885	COG0531	amino acid
HTZ91_RS12900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HTZ91_RS12910	COG1174	glycine betaine transport
HTZ91_RS12920	COG1174	glycine betaine transport
HTZ91_RS12940	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
HTZ91_RS12945	COG0531	amino acid
HTZ91_RS12950	COG2272	Belongs to the type-B carboxylesterase lipase family
HTZ91_RS12955	COG2814	Major facilitator Superfamily
HTZ91_RS12960	COG0390	transport system, permease component
HTZ91_RS12965	COG4619	ABC transporter
HTZ91_RS12970	COG1363	Peptidase, m42
HTZ91_RS12975	COG4808	Protein conserved in bacteria
HTZ91_RS12980	COG0069	glutamate synthase activity
HTZ91_RS12995	COG1124	(ABC) transporter
HTZ91_RS13005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HTZ91_RS13010	COG0601	transmembrane transport
HTZ91_RS13015	COG0747	negative chemotaxis
HTZ91_RS13035	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HTZ91_RS13040	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ91_RS13045	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
HTZ91_RS13050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HTZ91_RS13125	COG0494	nUDIX hydrolase
HTZ91_RS13165	COG1070	Carbohydrate kinase
HTZ91_RS13170	COG1802	Transcriptional regulator
HTZ91_RS13175	COG0789	Transcriptional regulator
HTZ91_RS13180	COG2357	RelA SpoT domain protein
HTZ91_RS13185	COG4876	unkown
HTZ91_RS13195	COG2271	Major facilitator Superfamily
HTZ91_RS13200	COG0586	Pfam SNARE associated Golgi protein
HTZ91_RS13205	COG1279	arginine transmembrane transporter activity
HTZ91_RS13215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTZ91_RS13220	COG1131	(ABC) transporter
HTZ91_RS13235	COG3949	Membrane
HTZ91_RS13240	COG0400	carboxylic ester hydrolase activity
HTZ91_RS13245	COG0346	lactoylglutathione lyase activity
HTZ91_RS13250	COG1846	Transcriptional regulator
HTZ91_RS13260	COG2514	catechol 2,3-dioxygenase activity
HTZ91_RS13280	COG0561	phosphatase activity
HTZ91_RS13285	COG3764	Sortase (surface protein transpeptidase)
HTZ91_RS13305	COG1760	l-serine dehydratase
HTZ91_RS13310	COG1760	l-serine dehydratase
HTZ91_RS13325	COG0697	spore germination
HTZ91_RS13330	COG0657	acetylesterase activity
HTZ91_RS13350	COG0028	Belongs to the TPP enzyme family
HTZ91_RS13365	COG0583	DNA-binding transcription factor activity
HTZ91_RS13375	COG3942	CHAP domain
HTZ91_RS13385	COG3425	synthase
HTZ91_RS13390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HTZ91_RS13415	COG2409	Drug exporters of the RND superfamily
HTZ91_RS13460	COG0436	Aminotransferase
HTZ91_RS13595	COG3001	Fructosamine kinase
HTZ91_RS13600	COG0167	dihydroorotate dehydrogenase activity
HTZ91_RS13650	COG3527	Alpha-acetolactate decarboxylase
HTZ91_RS13660	COG0531	amino acid
HTZ91_RS13690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HTZ91_RS13710	COG1012	belongs to the aldehyde dehydrogenase family
HTZ91_RS13720	COG1510	regulation of RNA biosynthetic process
HTZ91_RS13725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTZ91_RS13750	COG2851	Citrate transporter
HTZ91_RS13765	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HTZ91_RS13775	COG0386	Belongs to the glutathione peroxidase family
HTZ91_RS13795	COG1136	(ABC) transporter
HTZ91_RS13800	COG2205	protein histidine kinase activity
HTZ91_RS13805	COG0745	RESPONSE REGULATOR receiver
HTZ91_RS13815	COG1785	Belongs to the alkaline phosphatase family
HTZ91_RS13825	COG1846	Transcriptional regulator
HTZ91_RS13870	COG1438	arginine binding
HTZ91_RS13890	COG3711	transcriptional antiterminator
HTZ91_RS13890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HTZ91_RS13895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HTZ91_RS13895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HTZ91_RS13895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HTZ91_RS13900	COG1482	cell wall glycoprotein biosynthetic process
HTZ91_RS13910	COG3942	CHAP domain
HTZ91_RS13910	COG1705	Flagellar rod assembly protein muramidase FlgJ
HTZ91_RS13915	COG3433	isochorismatase activity
HTZ91_RS13915	COG1535	isochorismatase
HTZ91_RS13930	COG0438	transferase activity, transferring glycosyl groups
HTZ91_RS13945	COG1073	alpha beta
HTZ91_RS13965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTZ91_RS13985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTZ91_RS14070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HTZ91_RS14150	COG0471	metal ion transport
HTZ91_RS14155	COG2962	Rard protein
HTZ91_RS14165	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HTZ91_RS14180	COG1136	(ABC) transporter
HTZ91_RS14185	COG0577	efflux transmembrane transporter activity
HTZ91_RS14210	COG1404	Belongs to the peptidase S8 family
HTZ91_RS14215	COG1278	Cold shock
HTZ91_RS14235	COG1475	DNA binding