locus-tag	class	description
GAY69_RS00020	COG0740	serine-type endopeptidase activity
GAY69_RS00105	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAY69_RS00105	COG1388	LysM domain
GAY69_RS00140	COG1141	Ferredoxin
GAY69_RS00150	COG0514	ATP-dependent DNA helicase (RecQ)
GAY69_RS00165	COG0492	ferredoxin-NADP+ reductase activity
GAY69_RS00220	COG0142	geranyltranstransferase activity
GAY69_RS00260	COG4347	Protein of unknown function (DUF1405)
GAY69_RS00265	COG2738	Putative neutral zinc metallopeptidase
GAY69_RS00270	COG1694	Mazg nucleotide pyrophosphohydrolase
GAY69_RS00275	COG0438	transferase activity, transferring glycosyl groups
GAY69_RS00300	COG3935	DnaD domain protein
GAY69_RS00305	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GAY69_RS00315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GAY69_RS00315	COG4499	WXG100 protein secretion system (Wss), protein YukC
GAY69_RS00350	COG0116	Belongs to the methyltransferase superfamily
GAY69_RS00365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GAY69_RS00370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAY69_RS00385	COG0531	amino acid
GAY69_RS00405	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GAY69_RS00480	COG0671	phosphoesterase, PA-phosphatase related
GAY69_RS00520	COG0714	Associated with various cellular activities
GAY69_RS00525	COG4548	von Willebrand factor, type A
GAY69_RS00565	COG2808	Putative FMN-binding domain
GAY69_RS00600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GAY69_RS00605	COG0527	aspartate kinase activity
GAY69_RS00610	COG0488	(ABC) transporter
GAY69_RS00625	COG0573	inorganic phosphate transmembrane transporter activity
GAY69_RS00630	COG0581	inorganic phosphate transmembrane transporter activity
GAY69_RS00640	COG0704	Plays a role in the regulation of phosphate uptake
GAY69_RS00685	COG0561	phosphatase activity
GAY69_RS00725	COG0512	Glutamine amidotransferase of anthranilate synthase
GAY69_RS00730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GAY69_RS00735	COG1363	Peptidase, m42
GAY69_RS00745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GAY69_RS00770	COG0628	permease
GAY69_RS00785	COG1115	amino acid carrier protein
GAY69_RS00790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GAY69_RS00810	COG0824	Thioesterase
GAY69_RS00820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAY69_RS00840	COG4846	Membrane protein involved in cytochrome C biogenesis
GAY69_RS00875	COG2340	Cysteine-rich secretory protein family
GAY69_RS00905	COG0833	amino acid
GAY69_RS00930	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GAY69_RS00935	COG0460	homoserine dehydrogenase
GAY69_RS00940	COG0527	aspartate kinase activity
GAY69_RS00955	COG1525	nuclease
GAY69_RS01080	COG0789	Transcriptional regulator
GAY69_RS01085	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GAY69_RS01090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GAY69_RS01100	COG1923	regulation of RNA biosynthetic process
GAY69_RS01125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GAY69_RS01130	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GAY69_RS01165	COG1013	pyruvate-flavodoxin oxidoreductase activity
GAY69_RS01170	COG0674	pyruvate-flavodoxin oxidoreductase activity
GAY69_RS01170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GAY69_RS01175	COG1692	metallophosphoesterase
GAY69_RS01195	COG1546	Belongs to the CinA family
GAY69_RS01195	COG1058	Belongs to the CinA family
GAY69_RS01215	COG0300	oxidoreductase activity
GAY69_RS01220	COG0612	Peptidase, M16
GAY69_RS01225	COG0612	Peptidase, M16
GAY69_RS01230	COG2188	Transcriptional regulator
GAY69_RS01255	COG0196	riboflavin kinase activity
GAY69_RS01280	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GAY69_RS01285	COG0195	Participates in both transcription termination and antitermination
GAY69_RS01380	COG0758	DNA mediated transformation
GAY69_RS01385	COG2348	transferase activity, transferring amino-acyl groups
GAY69_RS01440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GAY69_RS01450	COG0552	protein localization to endoplasmic reticulum
GAY69_RS01455	COG1196	nuclear chromosome segregation
GAY69_RS01500	COG1302	Protein conserved in bacteria
GAY69_RS01515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GAY69_RS01530	COG0631	protein serine/threonine phosphatase activity
GAY69_RS01540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GAY69_RS01540	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GAY69_RS01555	COG2314	TM2 domain
GAY69_RS01565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GAY69_RS01570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GAY69_RS01585	COG1293	RNA-binding protein homologous to eukaryotic snRNP
GAY69_RS01630	COG2233	PERMEase
GAY69_RS01640	COG0564	pseudouridine synthase activity
GAY69_RS01655	COG2514	catechol 2,3-dioxygenase activity
GAY69_RS01665	COG3599	regulation of cell shape
GAY69_RS01670	COG2302	S4 RNA-binding domain
GAY69_RS01675	COG0762	integral membrane protein
GAY69_RS01685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GAY69_RS01700	COG0849	cell division
GAY69_RS01705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GAY69_RS01720	COG0768	penicillin binding
GAY69_RS01725	COG4839	cell division protein FtsL
GAY69_RS01750	COG1011	Hydrolase
GAY69_RS01785	COG1288	antiporter activity
GAY69_RS01890	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GAY69_RS01895	COG1053	succinate dehydrogenase
GAY69_RS01900	COG2009	succinate dehydrogenase
GAY69_RS01925	COG1796	DNA polymerase
GAY69_RS01925	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GAY69_RS01955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GAY69_RS01970	COG4509	Sortase family
GAY69_RS02025	COG0742	ribosomal rna small subunit methyltransferase
GAY69_RS02045	COG3679	Belongs to the UPF0342 family
GAY69_RS02075	COG0772	Belongs to the SEDS family
GAY69_RS02085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GAY69_RS02095	COG1217	gtp-binding protein TYPA
GAY69_RS02105	COG0483	inositol monophosphate 1-phosphatase activity
GAY69_RS02130	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GAY69_RS02135	COG1177	transmembrane transport
GAY69_RS02140	COG1176	ABC-type spermidine putrescine transport system, permease component I
GAY69_RS02205	COG0569	domain protein
GAY69_RS02210	COG1294	oxidase, subunit
GAY69_RS02215	COG1271	oxidase subunit
GAY69_RS02220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GAY69_RS02240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GAY69_RS02255	COG4721	ABC-type cobalt transport system, permease component
GAY69_RS02260	COG4172	Belongs to the ABC transporter superfamily
GAY69_RS02265	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GAY69_RS02305	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GAY69_RS02320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GAY69_RS02365	COG1316	TRANSCRIPTIONal
GAY69_RS02405	COG3594	Acyltransferase
GAY69_RS02410	COG0436	Aminotransferase
GAY69_RS02435	COG2267	carboxylic ester hydrolase activity
GAY69_RS02445	COG1169	isochorismate synthase
GAY69_RS02455	COG1575	Belongs to the MenA family. Type 1 subfamily
GAY69_RS02460	COG0456	acetyltransferase
GAY69_RS02465	COG2314	TM2 domain
GAY69_RS02475	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GAY69_RS02535	COG4873	Protein conserved in bacteria
GAY69_RS02550	COG4903	ComK protein
GAY69_RS02565	COG0737	Belongs to the 5'-nucleotidase family
GAY69_RS02570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GAY69_RS02580	COG0861	Integral membrane protein TerC family
GAY69_RS02630	COG1115	amino acid carrier protein
GAY69_RS02635	COG0628	permease
GAY69_RS02645	COG0475	glutathione-regulated potassium exporter activity
GAY69_RS02645	COG0569	domain protein
GAY69_RS02650	COG2239	Acts as a magnesium transporter
GAY69_RS02655	COG0564	pseudouridine synthase activity
GAY69_RS02665	COG2357	RelA SpoT domain protein
GAY69_RS02680	COG2346	COG2346, Truncated hemoglobins
GAY69_RS02690	COG1164	Oligoendopeptidase f
GAY69_RS02720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAY69_RS02725	COG0601	transmembrane transport
GAY69_RS02730	COG4608	Belongs to the ABC transporter superfamily
GAY69_RS02735	COG0444	Belongs to the ABC transporter superfamily
GAY69_RS02740	COG0747	negative chemotaxis
GAY69_RS02745	COG4166	transmembrane transport
GAY69_RS02750	COG4608	Belongs to the ABC transporter superfamily
GAY69_RS02755	COG0444	Belongs to the ABC transporter superfamily
GAY69_RS02760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAY69_RS02765	COG0601	transmembrane transport
GAY69_RS02795	COG1881	PFAM PEBP family protein
GAY69_RS02810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GAY69_RS02835	COG0561	phosphatase activity
GAY69_RS02875	COG0398	Pfam SNARE associated Golgi protein
GAY69_RS02895	COG0584	glycerophosphoryl diester phosphodiesterase
GAY69_RS02910	COG1902	pentaerythritol trinitrate reductase activity
GAY69_RS02915	COG1098	S1 RNA binding domain
GAY69_RS02970	COG2050	protein possibly involved in aromatic compounds catabolism
GAY69_RS02975	COG2056	Na+-H+ antiporter family
GAY69_RS02980	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GAY69_RS02990	COG0316	Belongs to the HesB IscA family
GAY69_RS03000	COG1252	NADH dehydrogenase
GAY69_RS03005	COG4837	Protein of unknown function (DUF1462)
GAY69_RS03010	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GAY69_RS03015	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GAY69_RS03025	COG1696	Membrane protein involved in D-alanine export
GAY69_RS03055	COG2445	Protein of unknown function DUF86
GAY69_RS03065	COG4470	Protein conserved in bacteria
GAY69_RS03080	COG0730	response to heat
GAY69_RS03085	COG1801	Protein of unknown function DUF72
GAY69_RS03100	COG1253	flavin adenine dinucleotide binding
GAY69_RS03120	COG0822	iron-sulfur transferase activity
GAY69_RS03130	COG0719	Fe-S assembly protein
GAY69_RS03135	COG0396	ATPase activity
GAY69_RS03175	COG5484	DNA packaging
GAY69_RS03175	COG3728	DNA packaging
GAY69_RS03280	COG0582	viral genome integration into host DNA
GAY69_RS03285	COG1464	Belongs to the NlpA lipoprotein family
GAY69_RS03290	COG2011	ABC-type metal ion transport system permease component
GAY69_RS03305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GAY69_RS03310	COG3878	Protein conserved in bacteria
GAY69_RS03325	COG1393	Belongs to the ArsC family
GAY69_RS03330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY69_RS03355	COG1279	arginine transmembrane transporter activity
GAY69_RS03360	COG0406	alpha-ribazole phosphatase activity
GAY69_RS03400	COG1278	Cold shock
GAY69_RS03465	COG0557	exoribonuclease II activity
GAY69_RS03470	COG1647	Serine aminopeptidase, S33
GAY69_RS03475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GAY69_RS03525	COG0281	malic enzyme
GAY69_RS03540	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GAY69_RS03595	COG1388	LysM domain
GAY69_RS03595	COG3942	CHAP domain
GAY69_RS03625	COG1040	competence protein
GAY69_RS03630	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GAY69_RS03640	COG1739	Uncharacterized protein family UPF0029
GAY69_RS03645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GAY69_RS03700	COG4607	ABC-type enterochelin transport system periplasmic component
GAY69_RS03705	COG4604	ABC transporter, ATP-binding protein
GAY69_RS03710	COG4605	iron ion homeostasis
GAY69_RS03715	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY69_RS03725	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAY69_RS03730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GAY69_RS03750	COG3104	oligopeptide transport
GAY69_RS03775	COG1174	glycine betaine transport
GAY69_RS03780	COG1125	glycine betaine transport
GAY69_RS03780	COG0517	IMP dehydrogenase activity
GAY69_RS03785	COG0514	ATP-dependent DNA helicase (RecQ)
GAY69_RS03790	COG0488	(ABC) transporter
GAY69_RS03820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GAY69_RS03825	COG0512	Glutamine amidotransferase of anthranilate synthase
GAY69_RS03825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GAY69_RS03835	COG0720	synthase
GAY69_RS03870	COG0463	Glycosyl transferase, family 2
GAY69_RS03875	COG0656	L-ascorbic acid biosynthetic process
GAY69_RS03880	COG1253	flavin adenine dinucleotide binding
GAY69_RS03885	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GAY69_RS03890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAY69_RS03890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY69_RS03890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAY69_RS03895	COG1105	Belongs to the carbohydrate kinase PfkB family
GAY69_RS03900	COG1349	DNA-binding transcription factor activity
GAY69_RS03905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GAY69_RS03930	COG0415	Belongs to the DNA photolyase family
GAY69_RS03935	COG0471	metal ion transport
GAY69_RS03945	COG4989	oxidoreductase activity
GAY69_RS03950	COG0523	cobalamin synthesis protein
GAY69_RS03960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GAY69_RS03965	COG4988	ABC transporter
GAY69_RS03985	COG1611	Belongs to the LOG family
GAY69_RS04015	COG2839	Protein conserved in bacteria
GAY69_RS04025	COG0583	DNA-binding transcription factor activity
GAY69_RS04055	COG4977	sequence-specific DNA binding
GAY69_RS04055	COG1917	Cupin 2, conserved barrel domain protein
GAY69_RS04065	COG1388	LysM domain
GAY69_RS04065	COG3942	CHAP domain
GAY69_RS04070	COG0306	phosphate transporter
GAY69_RS04075	COG1392	Phosphate transport regulator
GAY69_RS04080	COG0577	efflux transmembrane transporter activity
GAY69_RS04085	COG1136	(ABC) transporter
GAY69_RS04100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAY69_RS04120	COG3949	Membrane
GAY69_RS04130	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
GAY69_RS04140	COG2376	Dihydroxyacetone kinase
GAY69_RS04145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY69_RS04150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY69_RS04155	COG1120	ATPase activity
GAY69_RS04160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GAY69_RS04170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAY69_RS04175	COG1132	(ABC) transporter
GAY69_RS04180	COG1686	Belongs to the peptidase S11 family
GAY69_RS04185	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GAY69_RS04195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAY69_RS04200	COG1682	transport, permease protein
GAY69_RS04210	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GAY69_RS04220	COG1321	iron dependent repressor
GAY69_RS04225	COG1121	(ABC) transporter
GAY69_RS04230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAY69_RS04235	COG0803	Belongs to the bacterial solute-binding protein 9 family
GAY69_RS04280	COG4974	Belongs to the 'phage' integrase family
GAY69_RS04345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAY69_RS04375	COG1078	dGTPase activity
GAY69_RS04385	COG0655	NAD(P)H dehydrogenase (quinone) activity
GAY69_RS04390	COG0667	Aldo Keto reductase
GAY69_RS04440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAY69_RS04460	COG0083	homoserine kinase activity
GAY69_RS04465	COG0095	Lipoate-protein ligase
GAY69_RS04575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GAY69_RS04620	COG0561	phosphatase activity
GAY69_RS04630	COG1428	Deoxynucleoside kinase
GAY69_RS04635	COG1428	Deoxynucleoside kinase
GAY69_RS04640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GAY69_RS04670	COG1473	amidohydrolase
GAY69_RS04710	COG2813	Specifically methylates the guanine in position
GAY69_RS04770	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GAY69_RS04790	COG4956	integral membrane protein (PIN domain superfamily)
GAY69_RS04795	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GAY69_RS04810	COG3880	PFAM UvrB UvrC protein
GAY69_RS04820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAY69_RS04835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAY69_RS04930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GAY69_RS04955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GAY69_RS04970	COG1098	S1 RNA binding domain
GAY69_RS04980	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GAY69_RS04985	COG3956	TIGRFAM MazG family protein
GAY69_RS04990	COG2244	polysaccharide biosynthetic process
GAY69_RS05035	COG0251	oxidation-reduction process
GAY69_RS05040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GAY69_RS05050	COG4466	Protein conserved in bacteria
GAY69_RS05060	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GAY69_RS05065	COG0084	hydrolase, TatD family'
GAY69_RS05075	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GAY69_RS05085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GAY69_RS05095	COG1774	PSP1 C-terminal conserved region
GAY69_RS05100	COG0470	DNA polymerase III
GAY69_RS05105	COG3870	Protein conserved in bacteria
GAY69_RS05115	COG1982	Orn Lys Arg decarboxylase major
GAY69_RS05150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GAY69_RS05170	COG2188	Transcriptional regulator
GAY69_RS05175	COG0366	Alpha amylase catalytic
GAY69_RS05180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY69_RS05180	COG1263	PTS System
GAY69_RS05190	COG0493	'glutamate synthase
GAY69_RS05195	COG0067	glutamate synthase
GAY69_RS05195	COG0069	glutamate synthase activity
GAY69_RS05195	COG0070	glutamate synthase
GAY69_RS05200	COG0583	DNA-binding transcription factor activity
GAY69_RS05220	COG0494	nUDIX hydrolase
GAY69_RS05235	COG1464	Belongs to the NlpA lipoprotein family
GAY69_RS05240	COG2011	ABC-type metal ion transport system permease component
GAY69_RS05250	COG0626	cystathionine gamma-synthase activity
GAY69_RS05255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GAY69_RS05260	COG0733	neurotransmitter:sodium symporter activity
GAY69_RS05265	COG1647	Serine aminopeptidase, S33
GAY69_RS05280	COG5609	conserved protein (DUF2294)
GAY69_RS05290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GAY69_RS05315	COG0523	cobalamin synthesis protein
GAY69_RS05475	COG3759	membrane
GAY69_RS05485	COG1683	Conserved Protein
GAY69_RS05535	COG2233	PERMEase
GAY69_RS05565	COG1823	symporter activity
GAY69_RS05640	COG4974	Belongs to the 'phage' integrase family
GAY69_RS05680	COG0012	GTP binding
GAY69_RS05685	COG4481	Protein conserved in bacteria
GAY69_RS05690	COG0668	transmembrane transport
GAY69_RS05695	COG1475	DNA binding
GAY69_RS05700	COG0626	cystathionine gamma-synthase activity
GAY69_RS05705	COG0626	cystathionine gamma-synthase activity
GAY69_RS05710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GAY69_RS05710	COG0646	methionine synthase
GAY69_RS05740	COG1131	(ABC) transporter
GAY69_RS05750	COG1476	TRANSCRIPTIONal
GAY69_RS05760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GAY69_RS05765	COG0805	protein transport
GAY69_RS05770	COG0672	)-iron permease
GAY69_RS05780	COG2822	iron ion transport
GAY69_RS05785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY69_RS05795	COG0431	NADPH-dependent FMN reductase
GAY69_RS05800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAY69_RS05805	COG0346	lactoylglutathione lyase activity
GAY69_RS05810	COG2271	Major facilitator Superfamily
GAY69_RS05830	COG3711	transcriptional antiterminator
GAY69_RS05835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY69_RS05845	COG3037	sugar-specific permease SgaT UlaA
GAY69_RS05870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAY69_RS05895	COG3314	Sporulation integral membrane protein YlbJ
GAY69_RS05920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GAY69_RS05925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GAY69_RS05955	COG0577	efflux transmembrane transporter activity
GAY69_RS05960	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GAY69_RS05965	COG1114	Component of the transport system for branched-chain amino acids
GAY69_RS06090	COG1388	LysM domain
GAY69_RS06090	COG3942	CHAP domain
GAY69_RS06110	COG1131	(ABC) transporter
GAY69_RS06165	COG2226	methyltransferase
GAY69_RS06170	COG2723	6-phospho-beta-galactosidase activity
GAY69_RS06175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY69_RS06175	COG1263	PTS System
GAY69_RS06175	COG2190	(PTS) system
GAY69_RS06180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GAY69_RS06215	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAY69_RS06220	COG1063	alcohol dehydrogenase
GAY69_RS06230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAY69_RS06235	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GAY69_RS06240	COG1063	alcohol dehydrogenase
GAY69_RS06250	COG1063	alcohol dehydrogenase
GAY69_RS06260	COG1063	alcohol dehydrogenase
GAY69_RS06265	COG3775	system Galactitol-specific IIC component
GAY69_RS06270	COG3414	Phosphotransferase system galactitol-specific IIB component
GAY69_RS06290	COG1957	nucleoside hydrolase
GAY69_RS06295	COG1263	PTS System
GAY69_RS06295	COG2190	(PTS) system
GAY69_RS06295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY69_RS06320	COG3189	MarR family transcriptional regulator
GAY69_RS06325	COG0747	negative chemotaxis
GAY69_RS06340	COG0318	PFAM AMP-dependent synthetase and ligase
GAY69_RS06345	COG1960	acyl-CoA dehydrogenase activity
GAY69_RS06355	COG0183	Belongs to the thiolase family
GAY69_RS06410	COG1755	Isoprenylcysteine carboxyl methyltransferase
GAY69_RS06420	COG0673	inositol 2-dehydrogenase activity
GAY69_RS06425	COG0673	inositol 2-dehydrogenase activity
GAY69_RS06430	COG3833	ABC-type maltose transport systems, permease component
GAY69_RS06435	COG1175	transmembrane transport
GAY69_RS06445	COG3842	ATPase activity
GAY69_RS06465	COG0405	Gamma-glutamyltransferase
GAY69_RS06475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAY69_RS06480	COG0601	transmembrane transport
GAY69_RS06505	COG1737	Transcriptional regulator
GAY69_RS06535	COG3961	Belongs to the TPP enzyme family
GAY69_RS06540	COG1335	isochorismatase
GAY69_RS06545	COG1114	Component of the transport system for branched-chain amino acids
GAY69_RS06570	COG3477	response to acidic pH
GAY69_RS06590	COG1960	acyl-CoA dehydrogenase activity
GAY69_RS06595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GAY69_RS06630	COG2832	Protein of unknown function (DUF454)
GAY69_RS06640	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GAY69_RS06645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GAY69_RS06655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GAY69_RS06685	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GAY69_RS06695	COG1086	Polysaccharide biosynthesis protein
GAY69_RS06720	COG1454	alcohol dehydrogenase
GAY69_RS06720	COG1012	belongs to the aldehyde dehydrogenase family
GAY69_RS06735	COG0737	Belongs to the 5'-nucleotidase family
GAY69_RS06755	COG3639	organic phosphonate transmembrane transporter activity
GAY69_RS06775	COG2814	Major facilitator Superfamily
GAY69_RS06780	COG0813	purine-nucleoside phosphorylase activity
GAY69_RS06810	COG0438	transferase activity, transferring glycosyl groups
GAY69_RS06815	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GAY69_RS06820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GAY69_RS06845	COG1475	DNA binding
GAY69_RS06850	COG0019	diaminopimelate decarboxylase activity
GAY69_RS06860	COG4264	IucA IucC family
GAY69_RS06865	COG4264	IucA IucC family
GAY69_RS06870	COG2814	Major facilitator Superfamily
GAY69_RS06875	COG4264	IucA IucC family
GAY69_RS06880	COG2423	ornithine cyclodeaminase activity
GAY69_RS06890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GAY69_RS06895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY69_RS06900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY69_RS06920	COG1620	l-lactate permease
GAY69_RS06935	COG0697	spore germination
GAY69_RS06940	COG4716	Myosin-crossreactive antigen
GAY69_RS06945	COG1283	sodium-dependent phosphate transmembrane transporter activity
GAY69_RS06955	COG1473	amidohydrolase
GAY69_RS06970	COG0823	Involved in the tonB-independent uptake of proteins
GAY69_RS07005	COG0655	NAD(P)H dehydrogenase (quinone) activity
GAY69_RS07030	COG0456	acetyltransferase
GAY69_RS07035	COG1522	sequence-specific DNA binding
GAY69_RS07075	COG0076	glutamate decarboxylase activity
GAY69_RS07085	COG0210	DNA helicase
GAY69_RS07090	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GAY69_RS07095	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GAY69_RS07105	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GAY69_RS07135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GAY69_RS07195	COG2030	dehydratase
GAY69_RS07200	COG0584	glycerophosphoryl diester phosphodiesterase
GAY69_RS07205	COG3425	synthase
GAY69_RS07245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAY69_RS07245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAY69_RS07270	COG0737	Belongs to the 5'-nucleotidase family
GAY69_RS07275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GAY69_RS07285	COG4863	YycH protein
GAY69_RS07315	COG0305	Participates in initiation and elongation during chromosome replication
GAY69_RS07325	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GAY69_RS07335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GAY69_RS07360	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GAY69_RS07380	COG2501	S4 domain
GAY69_RS07425	COG1475	DNA binding
GAY69_RS07445	COG1278	Cold shock
GAY69_RS07485	COG1136	(ABC) transporter
GAY69_RS07500	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
GAY69_RS07510	COG2962	Rard protein
GAY69_RS07515	COG0471	metal ion transport
GAY69_RS07600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GAY69_RS07690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GAY69_RS07720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GAY69_RS07740	COG1073	alpha beta
GAY69_RS07755	COG0438	transferase activity, transferring glycosyl groups
GAY69_RS07770	COG1535	isochorismatase
GAY69_RS07770	COG3433	isochorismatase activity
GAY69_RS07775	COG1705	Flagellar rod assembly protein muramidase FlgJ
GAY69_RS07775	COG3942	CHAP domain
GAY69_RS07785	COG1482	cell wall glycoprotein biosynthetic process
GAY69_RS07790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAY69_RS07790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GAY69_RS07790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY69_RS07795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GAY69_RS07795	COG3711	transcriptional antiterminator
GAY69_RS07815	COG1438	arginine binding
GAY69_RS07860	COG1846	Transcriptional regulator
GAY69_RS07870	COG1785	Belongs to the alkaline phosphatase family
GAY69_RS07880	COG0745	RESPONSE REGULATOR receiver
GAY69_RS07885	COG2205	protein histidine kinase activity
GAY69_RS07890	COG1136	(ABC) transporter
GAY69_RS07910	COG0386	Belongs to the glutathione peroxidase family
GAY69_RS07920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GAY69_RS07930	COG2851	Citrate transporter
GAY69_RS07955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAY69_RS07960	COG1510	regulation of RNA biosynthetic process
GAY69_RS07970	COG1012	belongs to the aldehyde dehydrogenase family
GAY69_RS07990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GAY69_RS08020	COG0531	amino acid
GAY69_RS08030	COG3527	Alpha-acetolactate decarboxylase
GAY69_RS08035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GAY69_RS08115	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GAY69_RS08150	COG2226	methyltransferase
GAY69_RS08250	COG0167	dihydroorotate dehydrogenase activity
GAY69_RS08255	COG3001	Fructosamine kinase
GAY69_RS08290	COG0596	Alpha beta hydrolase
GAY69_RS08355	COG0456	acetyltransferase
GAY69_RS08395	COG0436	Aminotransferase
GAY69_RS08440	COG2409	Drug exporters of the RND superfamily
GAY69_RS08465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GAY69_RS08475	COG3425	synthase
GAY69_RS08485	COG3942	CHAP domain
GAY69_RS08495	COG0583	DNA-binding transcription factor activity
GAY69_RS08510	COG0028	Belongs to the TPP enzyme family
GAY69_RS08530	COG0657	acetylesterase activity
GAY69_RS08535	COG0697	spore germination
GAY69_RS08550	COG1760	l-serine dehydratase
GAY69_RS08555	COG1760	l-serine dehydratase
GAY69_RS08575	COG3764	Sortase (surface protein transpeptidase)
GAY69_RS08585	COG1131	(ABC) transporter
GAY69_RS08590	COG0561	phosphatase activity
GAY69_RS08605	COG2514	catechol 2,3-dioxygenase activity
GAY69_RS08620	COG1846	Transcriptional regulator
GAY69_RS08625	COG0346	lactoylglutathione lyase activity
GAY69_RS08630	COG0400	carboxylic ester hydrolase activity
GAY69_RS08660	COG1073	alpha beta
GAY69_RS08670	COG1073	alpha beta
GAY69_RS08680	COG1131	(ABC) transporter
GAY69_RS08690	COG0586	Pfam SNARE associated Golgi protein
GAY69_RS08695	COG2271	Major facilitator Superfamily
GAY69_RS08705	COG4876	unkown
GAY69_RS08710	COG2357	RelA SpoT domain protein
GAY69_RS08715	COG0789	Transcriptional regulator
GAY69_RS08720	COG1802	Transcriptional regulator
GAY69_RS08725	COG1070	Carbohydrate kinase
GAY69_RS08760	COG1846	Transcriptional regulator
GAY69_RS08800	COG0494	nUDIX hydrolase
GAY69_RS08910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GAY69_RS08915	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GAY69_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
GAY69_RS08945	COG0747	negative chemotaxis
GAY69_RS08950	COG0601	transmembrane transport
GAY69_RS08955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GAY69_RS08965	COG1124	(ABC) transporter
GAY69_RS08980	COG0069	glutamate synthase activity
GAY69_RS08985	COG4808	Protein conserved in bacteria
GAY69_RS08990	COG1363	Peptidase, m42
GAY69_RS08995	COG4619	ABC transporter
GAY69_RS09000	COG0390	transport system, permease component
GAY69_RS09005	COG2814	Major facilitator Superfamily
GAY69_RS09010	COG2272	Belongs to the type-B carboxylesterase lipase family
GAY69_RS09015	COG0531	amino acid
GAY69_RS09020	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GAY69_RS09040	COG1174	glycine betaine transport
GAY69_RS09050	COG1174	glycine betaine transport
GAY69_RS09060	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GAY69_RS09075	COG0531	amino acid
GAY69_RS09085	COG1113	amino acid transport
GAY69_RS09090	COG1408	metallophosphoesterase
GAY69_RS09105	COG2814	Major facilitator Superfamily
GAY69_RS09115	COG1929	Belongs to the glycerate kinase type-1 family
GAY69_RS09135	COG2375	cellular response to nickel ion
GAY69_RS09135	COG1132	(ABC) transporter
GAY69_RS09140	COG1132	(ABC) transporter
GAY69_RS09155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GAY69_RS09160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GAY69_RS09170	COG0156	8-amino-7-oxononanoate synthase activity
GAY69_RS09210	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GAY69_RS09225	COG2814	Major facilitator Superfamily
GAY69_RS09230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GAY69_RS09235	COG0765	amino acid transport
GAY69_RS09240	COG1126	abc transporter atp-binding protein
GAY69_RS09275	COG0803	Belongs to the bacterial solute-binding protein 9 family
GAY69_RS09275	COG3443	Belongs to the bacterial solute-binding protein 9 family
GAY69_RS09290	COG2116	formate transmembrane transporter activity
GAY69_RS09295	COG0454	-acetyltransferase
GAY69_RS09305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GAY69_RS09310	COG2146	nitrite reductase [NAD(P)H] activity
GAY69_RS09320	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GAY69_RS09325	COG1140	nitrate reductase beta subunit
GAY69_RS09335	COG2181	nitrate reductase activity
GAY69_RS09355	COG0789	Transcriptional regulator
GAY69_RS09395	COG3871	stress protein (general stress protein 26)
GAY69_RS09410	COG1263	PTS System
GAY69_RS09410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY69_RS09425	COG1511	domain protein
GAY69_RS09450	COG0604	alcohol dehydrogenase
GAY69_RS09470	COG1620	l-lactate permease
GAY69_RS09485	COG1131	(ABC) transporter
GAY69_RS09545	COG2814	Major facilitator Superfamily
GAY69_RS09560	COG1566	PFAM secretion protein HlyD family protein
GAY69_RS09565	COG2814	Major facilitator Superfamily
GAY69_RS09575	COG0657	acetylesterase activity
GAY69_RS09590	COG0598	Magnesium transport protein CorA
GAY69_RS09600	COG0786	glutamate:sodium symporter activity
GAY69_RS09610	COG3152	Membrane
GAY69_RS09615	COG4152	abc transporter atp-binding protein
GAY69_RS09620	COG1668	transmembrane transport
GAY69_RS09640	COG2258	MOSC domain
GAY69_RS09660	COG0583	DNA-binding transcription factor activity
GAY69_RS09675	COG1473	amidohydrolase
GAY69_RS09680	COG1028	Short-chain dehydrogenase reductase Sdr
GAY69_RS09700	COG1737	Transcriptional regulator
GAY69_RS09705	COG1263	PTS System
GAY69_RS09705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY69_RS09715	COG0385	Bile acid
GAY69_RS09720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GAY69_RS09740	COG1113	amino acid transport
GAY69_RS09770	COG1316	TRANSCRIPTIONal
GAY69_RS09805	COG3942	CHAP domain
GAY69_RS09820	COG1757	Na H antiporter
GAY69_RS09890	COG4413	Urea transporter
GAY69_RS09895	COG1960	acyl-CoA dehydrogenase activity
GAY69_RS09910	COG1268	BioY protein
GAY69_RS09925	COG0725	ABC transporter, periplasmic molybdate-binding protein
GAY69_RS09930	COG4149	molybdate abc transporter
GAY69_RS09935	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GAY69_RS09940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GAY69_RS09960	COG1763	Mo-molybdopterin cofactor biosynthetic process
GAY69_RS10020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GAY69_RS10065	COG2252	PERMEase
GAY69_RS10180	COG0201	protein transport
GAY69_RS10265	COG0028	Belongs to the TPP enzyme family
GAY69_RS10270	COG3527	Alpha-acetolactate decarboxylase
GAY69_RS10280	COG0693	protein deglycase activity
GAY69_RS10285	COG2378	regulation of single-species biofilm formation
GAY69_RS10290	COG5492	domain, Protein
GAY69_RS10300	COG0789	Transcriptional regulator
GAY69_RS10305	COG0656	L-ascorbic acid biosynthetic process
GAY69_RS10370	COG2130	NADP-dependent
GAY69_RS10380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GAY69_RS10405	COG2814	Major facilitator Superfamily
GAY69_RS10410	COG4264	IucA IucC family
GAY69_RS10415	COG3457	Alanine racemase
GAY69_RS10425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GAY69_RS10430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY69_RS10435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GAY69_RS10440	COG3314	Sporulation integral membrane protein YlbJ
GAY69_RS10450	COG1988	membrane-bound metal-dependent
GAY69_RS10460	COG1272	protein, Hemolysin III
GAY69_RS10475	COG2814	Major facilitator Superfamily
GAY69_RS10480	COG0489	protein tyrosine kinase activity
GAY69_RS10540	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GAY69_RS10570	COG3711	transcriptional antiterminator
GAY69_RS10585	COG1119	ATPase activity
GAY69_RS10590	COG0561	phosphatase activity
GAY69_RS10625	COG0640	Transcriptional regulator
GAY69_RS10630	COG0702	epimerase
GAY69_RS10635	COG1482	cell wall glycoprotein biosynthetic process
GAY69_RS10655	COG0783	Belongs to the Dps family
GAY69_RS10660	COG0813	purine-nucleoside phosphorylase activity
GAY69_RS10705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GAY69_RS10745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GAY69_RS10765	COG2890	protein-(glutamine-N5) methyltransferase activity
GAY69_RS10770	COG0009	L-threonylcarbamoyladenylate synthase
GAY69_RS10795	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GAY69_RS10880	COG0629	single-stranded DNA binding
GAY69_RS10930	COG1418	mRNA catabolic process
GAY69_RS10940	COG1937	Protein conserved in bacteria
GAY69_RS10955	COG0772	Belongs to the SEDS family
GAY69_RS10965	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GAY69_RS10975	COG0745	RESPONSE REGULATOR receiver
GAY69_RS10980	COG2205	protein histidine kinase activity
GAY69_RS11010	COG3428	Bacterial PH domain
GAY69_RS11040	COG2208	phosphoserine phosphatase activity
GAY69_RS11045	COG1366	Belongs to the anti-sigma-factor antagonist family
GAY69_RS11055	COG1191	sigma factor activity
GAY69_RS11060	COG2183	response to ionizing radiation
GAY69_RS11135	COG0028	Belongs to the TPP enzyme family
GAY69_RS11150	COG0802	atpase or kinase
GAY69_RS11155	COG1214	PFAM Peptidase M22, glycoprotease
GAY69_RS11160	COG0456	acetyltransferase
GAY69_RS11170	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GAY69_RS11185	COG0488	(ABC) transporter
GAY69_RS11195	COG2391	methyltransferase activity
GAY69_RS11200	COG0425	Belongs to the sulfur carrier protein TusA family
GAY69_RS11205	COG0004	ammonium transporteR
GAY69_RS11210	COG1609	Transcriptional regulator
GAY69_RS11215	COG1621	beta-fructofuranosidase activity
GAY69_RS11220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GAY69_RS11285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GAY69_RS11330	COG1725	Transcriptional regulator
GAY69_RS11345	COG1131	(ABC) transporter
GAY69_RS11395	COG1012	belongs to the aldehyde dehydrogenase family
GAY69_RS11410	COG1335	isochorismatase
GAY69_RS11420	COG0471	metal ion transport
GAY69_RS11430	COG0077	Prephenate dehydratase
GAY69_RS11440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GAY69_RS11475	COG4496	protein, YerC YecD
GAY69_RS11495	COG4851	CamS sex pheromone cAM373 precursor
GAY69_RS11610	COG1295	ribonuclease BN
GAY69_RS11630	COG2309	aminopeptidase activity
GAY69_RS11635	COG1607	acyl-coa hydrolase
GAY69_RS11640	COG0535	radical SAM domain protein
GAY69_RS11670	COG1134	teichoic acid transport
GAY69_RS11670	COG1388	LysM domain
GAY69_RS11680	COG1988	membrane-bound metal-dependent
GAY69_RS11685	COG1194	a g-specific adenine glycosylase
GAY69_RS11700	COG4129	membrane
GAY69_RS11710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GAY69_RS11715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GAY69_RS11890	COG1126	abc transporter atp-binding protein
GAY69_RS11895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GAY69_RS11925	COG0564	pseudouridine synthase activity
GAY69_RS11930	COG4585	Histidine kinase
GAY69_RS11930	COG2203	Gaf domain
GAY69_RS11935	COG2197	response regulator
GAY69_RS11955	COG0420	3'-5' exonuclease activity
GAY69_RS11985	COG0537	adenosine 5'-monophosphoramidase activity
GAY69_RS11990	COG1131	(ABC) transporter
GAY69_RS12020	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GAY69_RS12095	COG0860	N-Acetylmuramoyl-L-alanine amidase
GAY69_RS12095	COG1388	LysM domain
GAY69_RS12190	COG2816	NAD+ diphosphatase activity
GAY69_RS12195	COG1506	peptidase
GAY69_RS12215	COG0656	L-ascorbic acid biosynthetic process
GAY69_RS12235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GAY69_RS12270	COG5632	N-Acetylmuramoyl-L-alanine amidase
GAY69_RS12270	COG4193	domain, Protein
GAY69_RS12270	COG3266	domain, Protein
GAY69_RS12295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY69_RS12295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GAY69_RS12325	COG2267	carboxylic ester hydrolase activity
GAY69_RS12335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GAY69_RS12340	COG1242	4 iron, 4 sulfur cluster binding
GAY69_RS12345	COG2814	Major facilitator Superfamily
GAY69_RS12365	COG2081	HI0933 family
GAY69_RS12370	COG2244	polysaccharide biosynthetic process
GAY69_RS12375	COG1187	pseudouridine synthase activity
GAY69_RS12395	COG0510	thiamine kinase activity
GAY69_RS12405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY69_RS12415	COG1363	Peptidase, m42
GAY69_RS12420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GAY69_RS12430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GAY69_RS12435	COG1674	ftsk spoiiie
GAY69_RS12460	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GAY69_RS12460	COG1605	Chorismate mutase
GAY69_RS12480	COG0454	-acetyltransferase
GAY69_RS12485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GAY69_RS12520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GAY69_RS12525	COG0204	Acyl-transferase
GAY69_RS12530	COG1263	PTS System
GAY69_RS12530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GAY69_RS12550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GAY69_RS12555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GAY69_RS12560	COG1764	response to oxidative stress
GAY69_RS12565	COG0584	glycerophosphoryl diester phosphodiesterase
GAY69_RS12580	COG1956	GAF domain-containing protein
GAY69_RS12590	COG1104	cysteine desulfurase activity
GAY69_RS12600	COG0730	response to heat
GAY69_RS12610	COG0827	DNA restriction-modification system
GAY69_RS12650	COG4109	DRTGG domain
GAY69_RS12655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GAY69_RS12665	COG0281	malic enzyme
GAY69_RS12690	COG1113	amino acid transport
GAY69_RS12695	COG0372	Belongs to the citrate synthase family
GAY69_RS12705	COG0745	RESPONSE REGULATOR receiver
GAY69_RS12710	COG5002	protein histidine kinase activity
GAY69_RS12720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAY69_RS12720	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GAY69_RS12750	COG1484	DNA-dependent DNA replication
GAY69_RS12765	COG0833	amino acid
GAY69_RS12785	COG4112	unkown
GAY69_RS12820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GAY69_RS12855	COG2818	Glycosylase
GAY69_RS12865	COG0285	dihydrofolate synthase activity
GAY69_RS12870	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GAY69_RS12915	COG2868	ribosomal protein
GAY69_RS12955	COG1862	Preprotein translocase
GAY69_RS12960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GAY69_RS12960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GAY69_RS12965	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GAY69_RS12965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GAY69_RS13010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GAY69_RS13015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GAY69_RS13020	COG1959	2 iron, 2 sulfur cluster binding
GAY69_RS13025	COG3237	CsbD-like
GAY69_RS13035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GAY69_RS13040	COG1104	cysteine desulfurase activity
GAY69_RS13055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GAY69_RS13085	COG0826	peptidase U32
GAY69_RS13090	COG0826	peptidase U32
GAY69_RS13105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GAY69_RS13110	COG1984	allophanate hydrolase subunit 2
GAY69_RS13115	COG0511	ligase activity, forming carbon-carbon bonds
GAY69_RS13120	COG0439	Biotin carboxylase
GAY69_RS13130	COG1914	H( )-stimulated, divalent metal cation uptake system
GAY69_RS13135	COG3177	Filamentation induced by cAMP protein fic
GAY69_RS13160	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GAY69_RS13165	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GAY69_RS13175	COG1534	Rna-binding protein
GAY69_RS13185	COG1713	HD superfamily hydrolase involved in NAD metabolism
GAY69_RS13190	COG0799	negative regulation of ribosome biogenesis
GAY69_RS13195	COG2226	methyltransferase
GAY69_RS13205	COG2131	deaminase
GAY69_RS13210	COG0658	competence protein
GAY69_RS13210	COG2333	competence protein COMEC
GAY69_RS13215	COG1466	dna polymerase III delta subunit
GAY69_RS13230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GAY69_RS13260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GAY69_RS13265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GAY69_RS13275	COG1030	water channel activity
GAY69_RS13290	COG1702	phosphate starvation-inducible protein PhoH
GAY69_RS13300	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GAY69_RS13305	COG0295	cytidine deaminase activity
GAY69_RS13325	COG0517	IMP dehydrogenase activity
GAY69_RS13345	COG2384	SAM-dependent methyltransferase
GAY69_RS13355	COG0513	Belongs to the DEAD box helicase family
GAY69_RS13365	COG1121	(ABC) transporter
GAY69_RS13370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GAY69_RS13385	COG0768	penicillin binding
GAY69_RS13395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GAY69_RS13405	COG4483	Protein conserved in bacteria
GAY69_RS13410	COG1940	carbohydrate kinase activity
GAY69_RS13415	COG0011	TIGRFAM Protein of
GAY69_RS13420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GAY69_RS13425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GAY69_RS13430	COG1459	type II secretion system
GAY69_RS13435	COG4537	Required for transformation and DNA binding
GAY69_RS13480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GAY69_RS13485	COG0095	Lipoate-protein ligase
GAY69_RS13500	COG0006	proline dipeptidase activity
GAY69_RS13510	COG0511	ligase activity, forming carbon-carbon bonds
GAY69_RS13515	COG0439	Biotin carboxylase
GAY69_RS13520	COG1302	Protein conserved in bacteria
GAY69_RS13550	COG0497	DNA recombination
GAY69_RS13555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GAY69_RS13560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GAY69_RS13565	COG0022	dehydrogenase e1 component
GAY69_RS13570	COG0508	dehydrogenase complex catalyzes the overall conversion of
GAY69_RS13580	COG4129	membrane
GAY69_RS13590	COG2195	Cleaves the N-terminal amino acid of tripeptides
GAY69_RS13610	COG1609	Transcriptional regulator
GAY69_RS13615	COG0366	Alpha amylase catalytic
GAY69_RS13625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GAY69_RS13640	COG4221	oxidoreductase activity
GAY69_RS13650	COG0667	Aldo Keto reductase
GAY69_RS13655	COG0494	nUDIX hydrolase
GAY69_RS13660	COG0735	belongs to the Fur family
GAY69_RS13685	COG1187	pseudouridine synthase activity
GAY69_RS13690	COG0745	RESPONSE REGULATOR receiver
GAY69_RS13695	COG5002	protein histidine kinase activity
GAY69_RS13710	COG0582	viral genome integration into host DNA
GAY69_RS13825	COG0629	single-stranded DNA binding
GAY69_RS13845	COG1484	DNA-dependent DNA replication
GAY69_RS13955	COG0583	DNA-binding transcription factor activity
GAY69_RS14010	COG0589	response to stress
GAY69_RS14015	COG0659	secondary active sulfate transmembrane transporter activity
GAY69_RS14055	COG1846	Transcriptional regulator