locus-tag	class	description
OS075_RS00025	COG3173	Aminoglycoside phosphotransferase
OS075_RS00040	COG3093	addiction module antidote protein HigA
OS075_RS00090	COG0604	alcohol dehydrogenase
OS075_RS00110	COG3682	Transcriptional regulator
OS075_RS00140	COG0456	acetyltransferase
OS075_RS00200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OS075_RS00220	COG2188	Transcriptional regulator
OS075_RS00225	COG0366	Alpha amylase catalytic
OS075_RS00230	COG1263	PTS System
OS075_RS00230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OS075_RS00240	COG0493	'glutamate synthase
OS075_RS00245	COG0067	glutamate synthase
OS075_RS00245	COG0069	glutamate synthase activity
OS075_RS00245	COG0070	glutamate synthase
OS075_RS00250	COG0583	DNA-binding transcription factor activity
OS075_RS00285	COG1464	Belongs to the NlpA lipoprotein family
OS075_RS00290	COG2011	ABC-type metal ion transport system permease component
OS075_RS00300	COG0626	cystathionine gamma-synthase activity
OS075_RS00305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OS075_RS00310	COG0733	neurotransmitter:sodium symporter activity
OS075_RS00320	COG1647	Serine aminopeptidase, S33
OS075_RS00335	COG5609	conserved protein (DUF2294)
OS075_RS00345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OS075_RS00370	COG0523	cobalamin synthesis protein
OS075_RS00535	COG3759	membrane
OS075_RS00570	COG2233	PERMEase
OS075_RS00600	COG1823	symporter activity
OS075_RS00615	COG3634	alkyl hydroperoxide reductase activity
OS075_RS00700	COG0012	GTP binding
OS075_RS00705	COG4481	Protein conserved in bacteria
OS075_RS00710	COG0668	transmembrane transport
OS075_RS00715	COG1475	DNA binding
OS075_RS00720	COG0626	cystathionine gamma-synthase activity
OS075_RS00725	COG0626	cystathionine gamma-synthase activity
OS075_RS00730	COG0646	methionine synthase
OS075_RS00730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OS075_RS00760	COG1131	(ABC) transporter
OS075_RS00770	COG1476	TRANSCRIPTIONal
OS075_RS00780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OS075_RS00785	COG0805	protein transport
OS075_RS00790	COG0672	)-iron permease
OS075_RS00805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OS075_RS00820	COG0431	NADPH-dependent FMN reductase
OS075_RS00825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OS075_RS00830	COG0346	lactoylglutathione lyase activity
OS075_RS00835	COG2271	Major facilitator Superfamily
OS075_RS00855	COG3711	transcriptional antiterminator
OS075_RS00860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OS075_RS00870	COG3037	sugar-specific permease SgaT UlaA
OS075_RS00900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OS075_RS00925	COG3314	Sporulation integral membrane protein YlbJ
OS075_RS00950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OS075_RS00955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OS075_RS00985	COG0577	efflux transmembrane transporter activity
OS075_RS00990	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
OS075_RS00995	COG1114	Component of the transport system for branched-chain amino acids
OS075_RS01145	COG3942	CHAP domain
OS075_RS01145	COG1388	LysM domain
OS075_RS01175	COG1131	(ABC) transporter
OS075_RS01235	COG2226	methyltransferase
OS075_RS01240	COG2723	6-phospho-beta-galactosidase activity
OS075_RS01245	COG1263	PTS System
OS075_RS01245	COG2190	(PTS) system
OS075_RS01245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OS075_RS01250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OS075_RS01285	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OS075_RS01290	COG1063	alcohol dehydrogenase
OS075_RS01300	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OS075_RS01305	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OS075_RS01310	COG1063	alcohol dehydrogenase
OS075_RS01320	COG1063	alcohol dehydrogenase
OS075_RS01330	COG1063	alcohol dehydrogenase
OS075_RS01335	COG3775	system Galactitol-specific IIC component
OS075_RS01340	COG3414	Phosphotransferase system galactitol-specific IIB component
OS075_RS01360	COG1957	nucleoside hydrolase
OS075_RS01365	COG1263	PTS System
OS075_RS01365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OS075_RS01365	COG2190	(PTS) system
OS075_RS01395	COG3189	MarR family transcriptional regulator
OS075_RS01400	COG0747	negative chemotaxis
OS075_RS01415	COG0318	PFAM AMP-dependent synthetase and ligase
OS075_RS01420	COG1960	acyl-CoA dehydrogenase activity
OS075_RS01430	COG0183	Belongs to the thiolase family
OS075_RS01490	COG1755	Isoprenylcysteine carboxyl methyltransferase
OS075_RS01500	COG0673	inositol 2-dehydrogenase activity
OS075_RS01505	COG0673	inositol 2-dehydrogenase activity
OS075_RS01510	COG3833	ABC-type maltose transport systems, permease component
OS075_RS01515	COG1175	transmembrane transport
OS075_RS01525	COG3842	ATPase activity
OS075_RS01545	COG0405	Gamma-glutamyltransferase
OS075_RS01555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OS075_RS01560	COG0601	transmembrane transport
OS075_RS01595	COG1737	Transcriptional regulator
OS075_RS01625	COG3961	Belongs to the TPP enzyme family
OS075_RS01630	COG1335	isochorismatase
OS075_RS01635	COG1114	Component of the transport system for branched-chain amino acids
OS075_RS01685	COG5609	conserved protein (DUF2294)
OS075_RS01690	COG1960	acyl-CoA dehydrogenase activity
OS075_RS01695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OS075_RS01730	COG2832	Protein of unknown function (DUF454)
OS075_RS01740	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OS075_RS01745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OS075_RS01755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OS075_RS01785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OS075_RS01795	COG1086	Polysaccharide biosynthesis protein
OS075_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
OS075_RS01820	COG1454	alcohol dehydrogenase
OS075_RS01845	COG0737	Belongs to the 5'-nucleotidase family
OS075_RS01865	COG3639	organic phosphonate transmembrane transporter activity
OS075_RS01885	COG2814	Major facilitator Superfamily
OS075_RS01890	COG0813	purine-nucleoside phosphorylase activity
OS075_RS01925	COG0438	transferase activity, transferring glycosyl groups
OS075_RS01930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OS075_RS01935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OS075_RS01960	COG1475	DNA binding
OS075_RS01965	COG0019	diaminopimelate decarboxylase activity
OS075_RS01975	COG4264	IucA IucC family
OS075_RS01980	COG4264	IucA IucC family
OS075_RS01985	COG2814	Major facilitator Superfamily
OS075_RS01990	COG4264	IucA IucC family
OS075_RS01995	COG2423	ornithine cyclodeaminase activity
OS075_RS02005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OS075_RS02010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OS075_RS02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OS075_RS02030	COG1620	l-lactate permease
OS075_RS02045	COG0697	spore germination
OS075_RS02050	COG4716	Myosin-crossreactive antigen
OS075_RS02055	COG1283	sodium-dependent phosphate transmembrane transporter activity
OS075_RS02065	COG1473	amidohydrolase
OS075_RS02095	COG0823	Involved in the tonB-independent uptake of proteins
OS075_RS02115	COG0583	DNA-binding transcription factor activity
OS075_RS02165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OS075_RS02170	COG2210	Belongs to the sulfur carrier protein TusA family
OS075_RS02175	COG1937	Protein conserved in bacteria
OS075_RS02180	COG0730	response to heat
OS075_RS02210	COG1388	LysM domain
OS075_RS02225	COG1124	(ABC) transporter
OS075_RS02230	COG4172	Belongs to the ABC transporter superfamily
OS075_RS02235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OS075_RS02280	COG2235	arginine
OS075_RS02290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OS075_RS02295	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OS075_RS02340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OS075_RS02465	COG2030	dehydratase
OS075_RS02470	COG0584	glycerophosphoryl diester phosphodiesterase
OS075_RS02475	COG3425	synthase
OS075_RS02495	COG0737	Belongs to the 5'-nucleotidase family
OS075_RS02500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OS075_RS02510	COG4863	YycH protein
OS075_RS02540	COG0305	Participates in initiation and elongation during chromosome replication
OS075_RS02550	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OS075_RS02560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OS075_RS02585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OS075_RS02605	COG2501	S4 domain
OS075_RS02645	COG1475	DNA binding
OS075_RS02665	COG1278	Cold shock
OS075_RS02700	COG0577	efflux transmembrane transporter activity
OS075_RS02705	COG1136	(ABC) transporter
OS075_RS02720	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
OS075_RS02730	COG2962	Rard protein
OS075_RS02735	COG0471	metal ion transport
OS075_RS02820	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OS075_RS02850	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OS075_RS02905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OS075_RS02925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OS075_RS02945	COG1073	alpha beta
OS075_RS02960	COG0438	transferase activity, transferring glycosyl groups
OS075_RS02975	COG1535	isochorismatase
OS075_RS02975	COG3433	isochorismatase activity
OS075_RS02980	COG3942	CHAP domain
OS075_RS02980	COG1705	Flagellar rod assembly protein muramidase FlgJ
OS075_RS02990	COG1482	cell wall glycoprotein biosynthetic process
OS075_RS02995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OS075_RS02995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OS075_RS02995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OS075_RS03000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OS075_RS03000	COG3711	transcriptional antiterminator
OS075_RS03020	COG1438	arginine binding
OS075_RS03065	COG1846	Transcriptional regulator
OS075_RS03075	COG1785	Belongs to the alkaline phosphatase family
OS075_RS03085	COG0745	RESPONSE REGULATOR receiver
OS075_RS03090	COG2205	protein histidine kinase activity
OS075_RS03095	COG1136	(ABC) transporter
OS075_RS03115	COG0386	Belongs to the glutathione peroxidase family
OS075_RS03125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OS075_RS03140	COG2851	Citrate transporter
OS075_RS03165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OS075_RS03175	COG1510	regulation of RNA biosynthetic process
OS075_RS03185	COG1012	belongs to the aldehyde dehydrogenase family
OS075_RS03205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OS075_RS03235	COG0531	amino acid
OS075_RS03245	COG3527	Alpha-acetolactate decarboxylase
OS075_RS03250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OS075_RS03300	COG0167	dihydroorotate dehydrogenase activity
OS075_RS03305	COG3001	Fructosamine kinase
OS075_RS03410	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OS075_RS03410	COG2755	lipolytic protein G-D-S-L family
OS075_RS03415	COG3942	CHAP domain
OS075_RS03445	COG0436	Aminotransferase
OS075_RS03490	COG2409	Drug exporters of the RND superfamily
OS075_RS03510	COG0542	response to heat
OS075_RS03515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OS075_RS03520	COG3425	synthase
OS075_RS03545	COG3942	CHAP domain
OS075_RS03555	COG0583	DNA-binding transcription factor activity
OS075_RS03570	COG0028	Belongs to the TPP enzyme family
OS075_RS03590	COG0657	acetylesterase activity
OS075_RS03595	COG0697	spore germination
OS075_RS03610	COG1760	l-serine dehydratase
OS075_RS03615	COG1760	l-serine dehydratase
OS075_RS03635	COG3764	Sortase (surface protein transpeptidase)
OS075_RS03645	COG1131	(ABC) transporter
OS075_RS03650	COG0561	phosphatase activity
OS075_RS03665	COG2514	catechol 2,3-dioxygenase activity
OS075_RS03675	COG1846	Transcriptional regulator
OS075_RS03680	COG0346	lactoylglutathione lyase activity
OS075_RS03685	COG0400	carboxylic ester hydrolase activity
OS075_RS03690	COG3949	Membrane
OS075_RS03705	COG1131	(ABC) transporter
OS075_RS03710	COG1846	Transcriptional regulator
OS075_RS03715	COG2814	Major facilitator Superfamily
OS075_RS03725	COG0586	Pfam SNARE associated Golgi protein
OS075_RS03730	COG2271	Major facilitator Superfamily
OS075_RS03740	COG4876	unkown
OS075_RS03745	COG2357	RelA SpoT domain protein
OS075_RS03750	COG0789	Transcriptional regulator
OS075_RS03755	COG1802	Transcriptional regulator
OS075_RS03760	COG1070	Carbohydrate kinase
OS075_RS03790	COG1846	Transcriptional regulator
OS075_RS03795	COG1846	Transcriptional regulator
OS075_RS03830	COG0494	nUDIX hydrolase
OS075_RS03915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OS075_RS03920	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OS075_RS03950	COG0747	negative chemotaxis
OS075_RS03955	COG0601	transmembrane transport
OS075_RS03960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OS075_RS03965	COG0444	Belongs to the ABC transporter superfamily
OS075_RS03970	COG1124	(ABC) transporter
OS075_RS03985	COG0069	glutamate synthase activity
OS075_RS03990	COG4808	Protein conserved in bacteria
OS075_RS04010	COG1363	Peptidase, m42
OS075_RS04015	COG4619	ABC transporter
OS075_RS04020	COG0390	transport system, permease component
OS075_RS04025	COG2814	Major facilitator Superfamily
OS075_RS04030	COG2272	Belongs to the type-B carboxylesterase lipase family
OS075_RS04035	COG0531	amino acid
OS075_RS04040	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
OS075_RS04060	COG1174	glycine betaine transport
OS075_RS04070	COG1174	glycine betaine transport
OS075_RS04080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OS075_RS04095	COG0531	amino acid
OS075_RS04105	COG1113	amino acid transport
OS075_RS04125	COG2814	Major facilitator Superfamily
OS075_RS04135	COG1929	Belongs to the glycerate kinase type-1 family
OS075_RS04150	COG2375	cellular response to nickel ion
OS075_RS04150	COG1132	(ABC) transporter
OS075_RS04155	COG1132	(ABC) transporter
OS075_RS04165	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OS075_RS04170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OS075_RS04180	COG0156	8-amino-7-oxononanoate synthase activity
OS075_RS04220	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OS075_RS04235	COG2814	Major facilitator Superfamily
OS075_RS04240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OS075_RS04245	COG0765	amino acid transport
OS075_RS04250	COG1126	abc transporter atp-binding protein
OS075_RS04290	COG0803	Belongs to the bacterial solute-binding protein 9 family
OS075_RS04290	COG3443	Belongs to the bacterial solute-binding protein 9 family
OS075_RS04305	COG2116	formate transmembrane transporter activity
OS075_RS04310	COG0454	-acetyltransferase
OS075_RS04320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OS075_RS04325	COG2146	nitrite reductase [NAD(P)H] activity
OS075_RS04335	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OS075_RS04340	COG1140	nitrate reductase beta subunit
OS075_RS04350	COG2181	nitrate reductase activity
OS075_RS04370	COG0789	Transcriptional regulator
OS075_RS04410	COG3871	stress protein (general stress protein 26)
OS075_RS04425	COG1263	PTS System
OS075_RS04425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OS075_RS04440	COG1511	domain protein
OS075_RS04460	COG0456	acetyltransferase
OS075_RS04465	COG0604	alcohol dehydrogenase
OS075_RS04485	COG1620	l-lactate permease
OS075_RS04550	COG2814	Major facilitator Superfamily
OS075_RS04560	COG1566	PFAM secretion protein HlyD family protein
OS075_RS04565	COG2814	Major facilitator Superfamily
OS075_RS04575	COG0657	acetylesterase activity
OS075_RS04590	COG0598	Magnesium transport protein CorA
OS075_RS04600	COG0786	glutamate:sodium symporter activity
OS075_RS04610	COG3152	Membrane
OS075_RS04615	COG4152	abc transporter atp-binding protein
OS075_RS04620	COG1668	transmembrane transport
OS075_RS04640	COG2258	MOSC domain
OS075_RS04665	COG0583	DNA-binding transcription factor activity
OS075_RS04680	COG1473	amidohydrolase
OS075_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
OS075_RS04705	COG1737	Transcriptional regulator
OS075_RS04710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OS075_RS04710	COG1263	PTS System
OS075_RS04720	COG0385	Bile acid
OS075_RS04725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OS075_RS04745	COG1113	amino acid transport
OS075_RS04815	COG3942	CHAP domain
OS075_RS04830	COG1757	Na H antiporter
OS075_RS04840	COG3942	CHAP domain
OS075_RS04900	COG4413	Urea transporter
OS075_RS04905	COG1960	acyl-CoA dehydrogenase activity
OS075_RS04920	COG1268	BioY protein
OS075_RS04935	COG0725	ABC transporter, periplasmic molybdate-binding protein
OS075_RS04940	COG4149	molybdate abc transporter
OS075_RS04945	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OS075_RS04950	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OS075_RS04970	COG1763	Mo-molybdopterin cofactor biosynthetic process
OS075_RS05030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OS075_RS05075	COG2252	PERMEase
OS075_RS05190	COG0201	protein transport
OS075_RS05275	COG0542	response to heat
OS075_RS05295	COG0028	Belongs to the TPP enzyme family
OS075_RS05300	COG3527	Alpha-acetolactate decarboxylase
OS075_RS05320	COG5492	domain, Protein
OS075_RS05330	COG0789	Transcriptional regulator
OS075_RS05335	COG0656	L-ascorbic acid biosynthetic process
OS075_RS05360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OS075_RS05410	COG2130	NADP-dependent
OS075_RS05420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OS075_RS05450	COG2814	Major facilitator Superfamily
OS075_RS05455	COG4264	IucA IucC family
OS075_RS05460	COG3457	Alanine racemase
OS075_RS05470	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OS075_RS05475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OS075_RS05480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OS075_RS05485	COG3314	Sporulation integral membrane protein YlbJ
OS075_RS05495	COG1988	membrane-bound metal-dependent
OS075_RS05505	COG1272	protein, Hemolysin III
OS075_RS05520	COG2814	Major facilitator Superfamily
OS075_RS05525	COG0489	protein tyrosine kinase activity
OS075_RS05595	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OS075_RS05625	COG3711	transcriptional antiterminator
OS075_RS05640	COG1119	ATPase activity
OS075_RS05645	COG0561	phosphatase activity
OS075_RS05690	COG0640	Transcriptional regulator
OS075_RS05695	COG0702	epimerase
OS075_RS05700	COG1482	cell wall glycoprotein biosynthetic process
OS075_RS05720	COG0783	Belongs to the Dps family
OS075_RS05725	COG0813	purine-nucleoside phosphorylase activity
OS075_RS05770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OS075_RS05810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OS075_RS05830	COG2890	protein-(glutamine-N5) methyltransferase activity
OS075_RS05835	COG0009	L-threonylcarbamoyladenylate synthase
OS075_RS05860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OS075_RS05970	COG1418	mRNA catabolic process
OS075_RS05980	COG1937	Protein conserved in bacteria
OS075_RS05995	COG0772	Belongs to the SEDS family
OS075_RS06005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OS075_RS06015	COG0745	RESPONSE REGULATOR receiver
OS075_RS06020	COG2205	protein histidine kinase activity
OS075_RS06050	COG3428	Bacterial PH domain
OS075_RS06080	COG2208	phosphoserine phosphatase activity
OS075_RS06085	COG1366	Belongs to the anti-sigma-factor antagonist family
OS075_RS06095	COG1191	sigma factor activity
OS075_RS06100	COG2183	response to ionizing radiation
OS075_RS06170	COG0028	Belongs to the TPP enzyme family
OS075_RS06185	COG0802	atpase or kinase
OS075_RS06190	COG1214	PFAM Peptidase M22, glycoprotease
OS075_RS06195	COG0456	acetyltransferase
OS075_RS06205	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OS075_RS06215	COG0488	(ABC) transporter
OS075_RS06225	COG2391	methyltransferase activity
OS075_RS06230	COG0425	Belongs to the sulfur carrier protein TusA family
OS075_RS06235	COG0004	ammonium transporteR
OS075_RS06240	COG1609	Transcriptional regulator
OS075_RS06245	COG1621	beta-fructofuranosidase activity
OS075_RS06250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OS075_RS06325	COG5484	DNA packaging
OS075_RS06325	COG3728	DNA packaging
OS075_RS06340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OS075_RS06345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OS075_RS06350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OS075_RS06400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OS075_RS06580	COG0740	serine-type endopeptidase activity
OS075_RS06635	COG0739	heme binding
OS075_RS06680	COG5632	N-Acetylmuramoyl-L-alanine amidase
OS075_RS06680	COG1388	LysM domain
OS075_RS06740	COG1725	Transcriptional regulator
OS075_RS06755	COG1131	(ABC) transporter
OS075_RS06810	COG1012	belongs to the aldehyde dehydrogenase family
OS075_RS06825	COG1335	isochorismatase
OS075_RS06845	COG0077	Prephenate dehydratase
OS075_RS06855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OS075_RS06890	COG4496	protein, YerC YecD
OS075_RS06900	COG0210	DNA helicase
OS075_RS06910	COG4851	CamS sex pheromone cAM373 precursor
OS075_RS07020	COG2197	response regulator
OS075_RS07025	COG1295	ribonuclease BN
OS075_RS07045	COG2309	aminopeptidase activity
OS075_RS07050	COG1607	acyl-coa hydrolase
OS075_RS07055	COG0535	radical SAM domain protein
OS075_RS07085	COG1134	teichoic acid transport
OS075_RS07085	COG1388	LysM domain
OS075_RS07095	COG1988	membrane-bound metal-dependent
OS075_RS07120	COG4129	membrane
OS075_RS07130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OS075_RS07135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OS075_RS07315	COG0765	amino acid transport
OS075_RS07320	COG1126	abc transporter atp-binding protein
OS075_RS07325	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OS075_RS07355	COG0564	pseudouridine synthase activity
OS075_RS07360	COG4585	Histidine kinase
OS075_RS07360	COG2203	Gaf domain
OS075_RS07365	COG2197	response regulator
OS075_RS07390	COG0420	3'-5' exonuclease activity
OS075_RS07420	COG0537	adenosine 5'-monophosphoramidase activity
OS075_RS07425	COG1131	(ABC) transporter
OS075_RS07455	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OS075_RS07560	COG1131	(ABC) transporter
OS075_RS07725	COG1506	peptidase
OS075_RS07750	COG0656	L-ascorbic acid biosynthetic process
OS075_RS07775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OS075_RS07805	COG5632	N-Acetylmuramoyl-L-alanine amidase
OS075_RS07805	COG4193	domain, Protein
OS075_RS07805	COG3266	domain, Protein
OS075_RS07830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OS075_RS07830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OS075_RS07860	COG2267	carboxylic ester hydrolase activity
OS075_RS07875	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OS075_RS07880	COG1242	4 iron, 4 sulfur cluster binding
OS075_RS07885	COG2814	Major facilitator Superfamily
OS075_RS07905	COG2081	HI0933 family
OS075_RS07910	COG2244	polysaccharide biosynthetic process
OS075_RS07915	COG1187	pseudouridine synthase activity
OS075_RS07935	COG0510	thiamine kinase activity
OS075_RS07945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OS075_RS07955	COG1363	Peptidase, m42
OS075_RS07960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OS075_RS07970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OS075_RS07975	COG1674	ftsk spoiiie
OS075_RS08000	COG1605	Chorismate mutase
OS075_RS08000	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OS075_RS08020	COG0454	-acetyltransferase
OS075_RS08025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OS075_RS08055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OS075_RS08060	COG0204	Acyl-transferase
OS075_RS08065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OS075_RS08065	COG1263	PTS System
OS075_RS08080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OS075_RS08085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OS075_RS08090	COG1764	response to oxidative stress
OS075_RS08095	COG0584	glycerophosphoryl diester phosphodiesterase
OS075_RS08105	COG1956	GAF domain-containing protein
OS075_RS08120	COG1104	cysteine desulfurase activity
OS075_RS08140	COG0827	DNA restriction-modification system
OS075_RS08180	COG4109	DRTGG domain
OS075_RS08185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OS075_RS08195	COG0281	malic enzyme
OS075_RS08225	COG1113	amino acid transport
OS075_RS08230	COG0372	Belongs to the citrate synthase family
OS075_RS08240	COG0745	RESPONSE REGULATOR receiver
OS075_RS08245	COG5002	protein histidine kinase activity
OS075_RS08255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OS075_RS08255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OS075_RS08285	COG1484	DNA-dependent DNA replication
OS075_RS08300	COG0833	amino acid
OS075_RS08320	COG4112	unkown
OS075_RS08355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OS075_RS08390	COG2818	Glycosylase
OS075_RS08400	COG0285	dihydrofolate synthase activity
OS075_RS08405	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OS075_RS08450	COG2868	ribosomal protein
OS075_RS08490	COG1862	Preprotein translocase
OS075_RS08495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OS075_RS08495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OS075_RS08500	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OS075_RS08500	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OS075_RS08545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OS075_RS08550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OS075_RS08555	COG1959	2 iron, 2 sulfur cluster binding
OS075_RS08570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OS075_RS08575	COG1104	cysteine desulfurase activity
OS075_RS08590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OS075_RS08620	COG0826	peptidase U32
OS075_RS08625	COG0826	peptidase U32
OS075_RS08640	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OS075_RS08645	COG1984	allophanate hydrolase subunit 2
OS075_RS08650	COG0511	ligase activity, forming carbon-carbon bonds
OS075_RS08655	COG0439	Biotin carboxylase
OS075_RS08665	COG1914	H( )-stimulated, divalent metal cation uptake system
OS075_RS08670	COG3177	Filamentation induced by cAMP protein fic
OS075_RS08690	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OS075_RS08695	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OS075_RS08705	COG1534	Rna-binding protein
OS075_RS08715	COG1713	HD superfamily hydrolase involved in NAD metabolism
OS075_RS08720	COG0799	negative regulation of ribosome biogenesis
OS075_RS08725	COG2226	methyltransferase
OS075_RS08735	COG2131	deaminase
OS075_RS08740	COG0658	competence protein
OS075_RS08740	COG2333	competence protein COMEC
OS075_RS08745	COG1466	dna polymerase III delta subunit
OS075_RS08760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OS075_RS08790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OS075_RS08795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OS075_RS08805	COG1030	water channel activity
OS075_RS08820	COG1702	phosphate starvation-inducible protein PhoH
OS075_RS08835	COG0295	cytidine deaminase activity
OS075_RS08855	COG0517	IMP dehydrogenase activity
OS075_RS08875	COG2384	SAM-dependent methyltransferase
OS075_RS08885	COG0513	Belongs to the DEAD box helicase family
OS075_RS08895	COG1121	(ABC) transporter
OS075_RS08900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OS075_RS08915	COG0768	penicillin binding
OS075_RS08925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OS075_RS08935	COG4483	Protein conserved in bacteria
OS075_RS08940	COG1940	carbohydrate kinase activity
OS075_RS08945	COG0011	TIGRFAM Protein of
OS075_RS08950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OS075_RS08955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OS075_RS08960	COG1459	type II secretion system
OS075_RS08965	COG4537	Required for transformation and DNA binding
OS075_RS09010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OS075_RS09015	COG0095	Lipoate-protein ligase
OS075_RS09030	COG0006	proline dipeptidase activity
OS075_RS09040	COG0511	ligase activity, forming carbon-carbon bonds
OS075_RS09045	COG0439	Biotin carboxylase
OS075_RS09050	COG1302	Protein conserved in bacteria
OS075_RS09080	COG0497	DNA recombination
OS075_RS09085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OS075_RS09090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OS075_RS09095	COG0022	dehydrogenase e1 component
OS075_RS09100	COG0508	dehydrogenase complex catalyzes the overall conversion of
OS075_RS09110	COG4129	membrane
OS075_RS09120	COG2195	Cleaves the N-terminal amino acid of tripeptides
OS075_RS09140	COG1609	Transcriptional regulator
OS075_RS09145	COG0366	Alpha amylase catalytic
OS075_RS09155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OS075_RS09170	COG4221	oxidoreductase activity
OS075_RS09180	COG0667	Aldo Keto reductase
OS075_RS09185	COG0494	nUDIX hydrolase
OS075_RS09190	COG0735	belongs to the Fur family
OS075_RS09215	COG1187	pseudouridine synthase activity
OS075_RS09220	COG0745	RESPONSE REGULATOR receiver
OS075_RS09225	COG5002	protein histidine kinase activity
OS075_RS09240	COG0582	viral genome integration into host DNA
OS075_RS09500	COG5280	Phage tail tape measure protein TP901
OS075_RS09500	COG3953	SLT domain
OS075_RS09550	COG0860	N-Acetylmuramoyl-L-alanine amidase
OS075_RS09550	COG1388	LysM domain
OS075_RS09600	COG1141	Ferredoxin
OS075_RS09610	COG0514	ATP-dependent DNA helicase (RecQ)
OS075_RS09625	COG0492	ferredoxin-NADP+ reductase activity
OS075_RS09680	COG0142	geranyltranstransferase activity
OS075_RS09720	COG4347	Protein of unknown function (DUF1405)
OS075_RS09725	COG2738	Putative neutral zinc metallopeptidase
OS075_RS09730	COG1694	Mazg nucleotide pyrophosphohydrolase
OS075_RS09735	COG0438	transferase activity, transferring glycosyl groups
OS075_RS09760	COG3935	DnaD domain protein
OS075_RS09765	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OS075_RS09775	COG4499	WXG100 protein secretion system (Wss), protein YukC
OS075_RS09775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OS075_RS09810	COG0116	Belongs to the methyltransferase superfamily
OS075_RS09825	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OS075_RS09830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OS075_RS09845	COG0531	amino acid
OS075_RS09870	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OS075_RS09945	COG0671	phosphoesterase, PA-phosphatase related
OS075_RS10000	COG4548	von Willebrand factor, type A
OS075_RS10075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OS075_RS10080	COG0527	aspartate kinase activity
OS075_RS10085	COG0488	(ABC) transporter
OS075_RS10105	COG0573	inorganic phosphate transmembrane transporter activity
OS075_RS10110	COG0581	inorganic phosphate transmembrane transporter activity
OS075_RS10120	COG0704	Plays a role in the regulation of phosphate uptake
OS075_RS10165	COG0561	phosphatase activity
OS075_RS10205	COG0512	Glutamine amidotransferase of anthranilate synthase
OS075_RS10210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OS075_RS10215	COG1363	Peptidase, m42
OS075_RS10225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OS075_RS10245	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OS075_RS10245	COG0392	lysyltransferase activity
OS075_RS10250	COG0628	permease
OS075_RS10265	COG1115	amino acid carrier protein
OS075_RS10290	COG0824	Thioesterase
OS075_RS10300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OS075_RS10320	COG4846	Membrane protein involved in cytochrome C biogenesis
OS075_RS10355	COG2340	Cysteine-rich secretory protein family
OS075_RS10385	COG0833	amino acid
OS075_RS10410	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OS075_RS10415	COG0460	homoserine dehydrogenase
OS075_RS10420	COG0527	aspartate kinase activity
OS075_RS10435	COG1525	nuclease
OS075_RS10445	COG2197	response regulator
OS075_RS10460	COG1131	(ABC) transporter
OS075_RS10560	COG0789	Transcriptional regulator
OS075_RS10565	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OS075_RS10570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OS075_RS10580	COG1923	regulation of RNA biosynthetic process
OS075_RS10605	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OS075_RS10610	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OS075_RS10645	COG1013	pyruvate-flavodoxin oxidoreductase activity
OS075_RS10650	COG0674	pyruvate-flavodoxin oxidoreductase activity
OS075_RS10650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OS075_RS10655	COG1692	metallophosphoesterase
OS075_RS10675	COG1058	Belongs to the CinA family
OS075_RS10675	COG1546	Belongs to the CinA family
OS075_RS10695	COG0300	oxidoreductase activity
OS075_RS10700	COG0612	Peptidase, M16
OS075_RS10705	COG0612	Peptidase, M16
OS075_RS10710	COG2188	Transcriptional regulator
OS075_RS10735	COG0196	riboflavin kinase activity
OS075_RS10760	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OS075_RS10765	COG0195	Participates in both transcription termination and antitermination
OS075_RS10860	COG0758	DNA mediated transformation
OS075_RS10920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OS075_RS10930	COG0552	protein localization to endoplasmic reticulum
OS075_RS10935	COG1196	nuclear chromosome segregation
OS075_RS10970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OS075_RS10980	COG1302	Protein conserved in bacteria
OS075_RS10995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OS075_RS11010	COG0631	protein serine/threonine phosphatase activity
OS075_RS11020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OS075_RS11020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OS075_RS11035	COG2314	TM2 domain
OS075_RS11045	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OS075_RS11050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OS075_RS11065	COG1293	RNA-binding protein homologous to eukaryotic snRNP
OS075_RS11110	COG2233	PERMEase
OS075_RS11120	COG0564	pseudouridine synthase activity
OS075_RS11135	COG2514	catechol 2,3-dioxygenase activity
OS075_RS11145	COG3599	regulation of cell shape
OS075_RS11150	COG2302	S4 RNA-binding domain
OS075_RS11155	COG0762	integral membrane protein
OS075_RS11165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OS075_RS11180	COG0849	cell division
OS075_RS11185	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OS075_RS11200	COG0768	penicillin binding
OS075_RS11205	COG4839	cell division protein FtsL
OS075_RS11230	COG1011	Hydrolase
OS075_RS11265	COG1288	antiporter activity
OS075_RS11370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OS075_RS11375	COG1053	succinate dehydrogenase
OS075_RS11380	COG2009	succinate dehydrogenase
OS075_RS11405	COG1796	DNA polymerase
OS075_RS11405	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OS075_RS11435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OS075_RS11450	COG4509	Sortase family
OS075_RS11505	COG0742	ribosomal rna small subunit methyltransferase
OS075_RS11525	COG3679	Belongs to the UPF0342 family
OS075_RS11555	COG0772	Belongs to the SEDS family
OS075_RS11565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OS075_RS11575	COG1217	gtp-binding protein TYPA
OS075_RS11585	COG0483	inositol monophosphate 1-phosphatase activity
OS075_RS11610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OS075_RS11615	COG1177	transmembrane transport
OS075_RS11620	COG1176	ABC-type spermidine putrescine transport system, permease component I
OS075_RS11685	COG0569	domain protein
OS075_RS11690	COG1294	oxidase, subunit
OS075_RS11695	COG1271	oxidase subunit
OS075_RS11720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OS075_RS11735	COG4721	ABC-type cobalt transport system, permease component
OS075_RS11740	COG4172	Belongs to the ABC transporter superfamily
OS075_RS11745	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OS075_RS11785	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OS075_RS11800	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OS075_RS11840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OS075_RS11845	COG1316	TRANSCRIPTIONal
OS075_RS11875	COG3594	Acyltransferase
OS075_RS11880	COG0436	Aminotransferase
OS075_RS11905	COG2267	carboxylic ester hydrolase activity
OS075_RS11915	COG1169	isochorismate synthase
OS075_RS11925	COG1575	Belongs to the MenA family. Type 1 subfamily
OS075_RS11930	COG0456	acetyltransferase
OS075_RS11935	COG2314	TM2 domain
OS075_RS11945	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OS075_RS12005	COG4873	Protein conserved in bacteria
OS075_RS12020	COG4903	ComK protein
OS075_RS12035	COG0737	Belongs to the 5'-nucleotidase family
OS075_RS12040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OS075_RS12050	COG0861	Integral membrane protein TerC family
OS075_RS12090	COG1115	amino acid carrier protein
OS075_RS12095	COG0628	permease
OS075_RS12105	COG0569	domain protein
OS075_RS12105	COG0475	glutathione-regulated potassium exporter activity
OS075_RS12110	COG2239	Acts as a magnesium transporter
OS075_RS12115	COG0564	pseudouridine synthase activity
OS075_RS12125	COG2357	RelA SpoT domain protein
OS075_RS12140	COG2346	COG2346, Truncated hemoglobins
OS075_RS12150	COG1164	Oligoendopeptidase f
OS075_RS12175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OS075_RS12180	COG0601	transmembrane transport
OS075_RS12185	COG4608	Belongs to the ABC transporter superfamily
OS075_RS12190	COG0444	Belongs to the ABC transporter superfamily
OS075_RS12195	COG0747	negative chemotaxis
OS075_RS12200	COG4166	transmembrane transport
OS075_RS12205	COG4608	Belongs to the ABC transporter superfamily
OS075_RS12210	COG0444	Belongs to the ABC transporter superfamily
OS075_RS12215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OS075_RS12220	COG0601	transmembrane transport
OS075_RS12250	COG1881	PFAM PEBP family protein
OS075_RS12265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OS075_RS12290	COG0561	phosphatase activity
OS075_RS12330	COG0398	Pfam SNARE associated Golgi protein
OS075_RS12350	COG0584	glycerophosphoryl diester phosphodiesterase
OS075_RS12365	COG1902	pentaerythritol trinitrate reductase activity
OS075_RS12370	COG1098	S1 RNA binding domain
OS075_RS12425	COG2050	protein possibly involved in aromatic compounds catabolism
OS075_RS12430	COG2056	Na+-H+ antiporter family
OS075_RS12435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OS075_RS12445	COG0316	Belongs to the HesB IscA family
OS075_RS12455	COG1252	NADH dehydrogenase
OS075_RS12460	COG4837	Protein of unknown function (DUF1462)
OS075_RS12465	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OS075_RS12470	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OS075_RS12480	COG1696	Membrane protein involved in D-alanine export
OS075_RS12510	COG2445	Protein of unknown function DUF86
OS075_RS12520	COG4470	Protein conserved in bacteria
OS075_RS12535	COG0730	response to heat
OS075_RS12540	COG1801	Protein of unknown function DUF72
OS075_RS12555	COG1253	flavin adenine dinucleotide binding
OS075_RS12805	COG1484	DNA-dependent DNA replication
OS075_RS12915	COG0822	iron-sulfur transferase activity
OS075_RS12925	COG0719	Fe-S assembly protein
OS075_RS12930	COG0396	ATPase activity
OS075_RS12945	COG1464	Belongs to the NlpA lipoprotein family
OS075_RS12950	COG2011	ABC-type metal ion transport system permease component
OS075_RS12965	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OS075_RS12970	COG3878	Protein conserved in bacteria
OS075_RS12980	COG1393	Belongs to the ArsC family
OS075_RS12985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OS075_RS13010	COG1279	arginine transmembrane transporter activity
OS075_RS13015	COG0406	alpha-ribazole phosphatase activity
OS075_RS13055	COG1278	Cold shock
OS075_RS13125	COG0557	exoribonuclease II activity
OS075_RS13130	COG1647	Serine aminopeptidase, S33
OS075_RS13135	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OS075_RS13195	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OS075_RS13250	COG1388	LysM domain
OS075_RS13250	COG3942	CHAP domain
OS075_RS13280	COG1040	competence protein
OS075_RS13285	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OS075_RS13295	COG1739	Uncharacterized protein family UPF0029
OS075_RS13300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OS075_RS13355	COG4607	ABC-type enterochelin transport system periplasmic component
OS075_RS13360	COG4604	ABC transporter, ATP-binding protein
OS075_RS13365	COG4605	iron ion homeostasis
OS075_RS13370	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OS075_RS13380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OS075_RS13385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OS075_RS13410	COG3104	oligopeptide transport
OS075_RS13435	COG1174	glycine betaine transport
OS075_RS13440	COG1125	glycine betaine transport
OS075_RS13440	COG0517	IMP dehydrogenase activity
OS075_RS13445	COG0514	ATP-dependent DNA helicase (RecQ)
OS075_RS13450	COG0488	(ABC) transporter
OS075_RS13480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OS075_RS13485	COG0512	Glutamine amidotransferase of anthranilate synthase
OS075_RS13485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OS075_RS13495	COG0720	synthase
OS075_RS13530	COG0463	Glycosyl transferase, family 2
OS075_RS13535	COG0656	L-ascorbic acid biosynthetic process
OS075_RS13540	COG1253	flavin adenine dinucleotide binding
OS075_RS13545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OS075_RS13550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OS075_RS13550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OS075_RS13550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OS075_RS13555	COG1105	Belongs to the carbohydrate kinase PfkB family
OS075_RS13560	COG1349	DNA-binding transcription factor activity
OS075_RS13565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OS075_RS13595	COG0415	Belongs to the DNA photolyase family
OS075_RS13600	COG0471	metal ion transport
OS075_RS13610	COG4989	oxidoreductase activity
OS075_RS13615	COG0523	cobalamin synthesis protein
OS075_RS13625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OS075_RS13630	COG4988	ABC transporter
OS075_RS13650	COG1611	Belongs to the LOG family
OS075_RS13680	COG2839	Protein conserved in bacteria
OS075_RS13685	COG2814	Major facilitator Superfamily
OS075_RS13690	COG0583	DNA-binding transcription factor activity
OS075_RS13730	COG3942	CHAP domain
OS075_RS13730	COG1388	LysM domain
OS075_RS13735	COG0306	phosphate transporter
OS075_RS13740	COG1392	Phosphate transport regulator
OS075_RS13745	COG0577	efflux transmembrane transporter activity
OS075_RS13750	COG1136	(ABC) transporter
OS075_RS13765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OS075_RS13785	COG3949	Membrane
OS075_RS13795	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
OS075_RS13805	COG2376	Dihydroxyacetone kinase
OS075_RS13810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OS075_RS13815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OS075_RS13820	COG1120	ATPase activity
OS075_RS13825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OS075_RS13835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OS075_RS13840	COG1132	(ABC) transporter
OS075_RS13845	COG1686	Belongs to the peptidase S11 family
OS075_RS13850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OS075_RS13855	COG1216	Glycosyl transferase, family 2
OS075_RS13860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OS075_RS13865	COG1682	transport, permease protein
OS075_RS13875	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
OS075_RS13885	COG1321	iron dependent repressor
OS075_RS13890	COG1121	(ABC) transporter
OS075_RS13895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OS075_RS13900	COG0803	Belongs to the bacterial solute-binding protein 9 family
OS075_RS13945	COG4974	Belongs to the 'phage' integrase family
OS075_RS13980	COG2946	Replication initiation factor
OS075_RS14000	COG0433	COG0433 Predicted ATPase
OS075_RS14005	COG1674	ftsk spoiiie
OS075_RS14035	COG2826	transposase and inactivated derivatives, IS30 family
OS075_RS14075	COG4139	cobalamin transport
OS075_RS14080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OS075_RS14115	COG1078	dGTPase activity
OS075_RS14125	COG0655	NAD(P)H dehydrogenase (quinone) activity
OS075_RS14130	COG0667	Aldo Keto reductase
OS075_RS14215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OS075_RS14235	COG0083	homoserine kinase activity
OS075_RS14240	COG0095	Lipoate-protein ligase
OS075_RS14345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OS075_RS14385	COG0561	phosphatase activity
OS075_RS14395	COG1428	Deoxynucleoside kinase
OS075_RS14400	COG1428	Deoxynucleoside kinase
OS075_RS14405	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OS075_RS14435	COG1473	amidohydrolase
OS075_RS14475	COG2813	Specifically methylates the guanine in position
OS075_RS14530	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OS075_RS14550	COG4956	integral membrane protein (PIN domain superfamily)
OS075_RS14555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OS075_RS14570	COG3880	PFAM UvrB UvrC protein
OS075_RS14580	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OS075_RS14595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OS075_RS14690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OS075_RS14715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OS075_RS14730	COG1098	S1 RNA binding domain
OS075_RS14740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OS075_RS14745	COG3956	TIGRFAM MazG family protein
OS075_RS14750	COG2244	polysaccharide biosynthetic process
OS075_RS14790	COG0251	oxidation-reduction process
OS075_RS14795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OS075_RS14805	COG4466	Protein conserved in bacteria
OS075_RS14815	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OS075_RS14820	COG0084	hydrolase, TatD family'
OS075_RS14830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OS075_RS14840	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OS075_RS14850	COG1774	PSP1 C-terminal conserved region
OS075_RS14855	COG0470	DNA polymerase III
OS075_RS14860	COG3870	Protein conserved in bacteria
OS075_RS14870	COG1982	Orn Lys Arg decarboxylase major