locus-tag	class	description
JF380_RS00015	COG2501	S4 domain
JF380_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JF380_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JF380_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JF380_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JF380_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
JF380_RS00110	COG4863	YycH protein
JF380_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JF380_RS00125	COG0737	Belongs to the 5'-nucleotidase family
JF380_RS00140	COG1401	restriction endodeoxyribonuclease activity
JF380_RS00150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JF380_RS00150	COG1199	ATP-dependent helicase activity
JF380_RS00155	COG0456	acetyltransferase
JF380_RS00170	COG0730	response to heat
JF380_RS00175	COG1937	Protein conserved in bacteria
JF380_RS00180	COG2210	Belongs to the sulfur carrier protein TusA family
JF380_RS00185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JF380_RS00215	COG1073	alpha beta
JF380_RS00225	COG2226	methyltransferase
JF380_RS00235	COG0823	Involved in the tonB-independent uptake of proteins
JF380_RS00290	COG1473	amidohydrolase
JF380_RS00305	COG1283	sodium-dependent phosphate transmembrane transporter activity
JF380_RS00310	COG4716	Myosin-crossreactive antigen
JF380_RS00315	COG0697	spore germination
JF380_RS00330	COG1620	l-lactate permease
JF380_RS00345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF380_RS00350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF380_RS00355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JF380_RS00365	COG2423	ornithine cyclodeaminase activity
JF380_RS00370	COG4264	IucA IucC family
JF380_RS00375	COG2814	Major facilitator Superfamily
JF380_RS00380	COG4264	IucA IucC family
JF380_RS00385	COG4264	IucA IucC family
JF380_RS00395	COG0019	diaminopimelate decarboxylase activity
JF380_RS00400	COG1475	DNA binding
JF380_RS00425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JF380_RS00430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JF380_RS00435	COG0438	transferase activity, transferring glycosyl groups
JF380_RS00465	COG0813	purine-nucleoside phosphorylase activity
JF380_RS00470	COG2814	Major facilitator Superfamily
JF380_RS00490	COG3639	organic phosphonate transmembrane transporter activity
JF380_RS00510	COG0737	Belongs to the 5'-nucleotidase family
JF380_RS00525	COG1012	belongs to the aldehyde dehydrogenase family
JF380_RS00525	COG1454	alcohol dehydrogenase
JF380_RS00550	COG1086	Polysaccharide biosynthesis protein
JF380_RS00560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JF380_RS00590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JF380_RS00600	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JF380_RS00605	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JF380_RS00615	COG2832	Protein of unknown function (DUF454)
JF380_RS00650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JF380_RS00655	COG1960	acyl-CoA dehydrogenase activity
JF380_RS00660	COG5609	conserved protein (DUF2294)
JF380_RS00710	COG1114	Component of the transport system for branched-chain amino acids
JF380_RS00715	COG1335	isochorismatase
JF380_RS00720	COG3961	Belongs to the TPP enzyme family
JF380_RS00750	COG1737	Transcriptional regulator
JF380_RS00790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JF380_RS00800	COG0405	Gamma-glutamyltransferase
JF380_RS00820	COG3842	ATPase activity
JF380_RS00830	COG1175	transmembrane transport
JF380_RS00835	COG3833	ABC-type maltose transport systems, permease component
JF380_RS00840	COG0673	inositol 2-dehydrogenase activity
JF380_RS00845	COG0673	inositol 2-dehydrogenase activity
JF380_RS00855	COG1755	Isoprenylcysteine carboxyl methyltransferase
JF380_RS00910	COG0183	Belongs to the thiolase family
JF380_RS00920	COG1960	acyl-CoA dehydrogenase activity
JF380_RS00925	COG0318	PFAM AMP-dependent synthetase and ligase
JF380_RS00940	COG0747	negative chemotaxis
JF380_RS00945	COG3189	MarR family transcriptional regulator
JF380_RS00970	COG2190	(PTS) system
JF380_RS00970	COG1263	PTS System
JF380_RS00970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JF380_RS00975	COG1957	nucleoside hydrolase
JF380_RS00995	COG3414	Phosphotransferase system galactitol-specific IIB component
JF380_RS01000	COG3775	system Galactitol-specific IIC component
JF380_RS01005	COG1063	alcohol dehydrogenase
JF380_RS01015	COG1063	alcohol dehydrogenase
JF380_RS01025	COG1063	alcohol dehydrogenase
JF380_RS01030	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JF380_RS01035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JF380_RS01045	COG1063	alcohol dehydrogenase
JF380_RS01050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JF380_RS01085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JF380_RS01095	COG2723	6-phospho-beta-galactosidase activity
JF380_RS01100	COG2226	methyltransferase
JF380_RS01160	COG1131	(ABC) transporter
JF380_RS01180	COG3942	CHAP domain
JF380_RS01180	COG1388	LysM domain
JF380_RS01305	COG1114	Component of the transport system for branched-chain amino acids
JF380_RS01310	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JF380_RS01315	COG0577	efflux transmembrane transporter activity
JF380_RS01340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JF380_RS01345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JF380_RS01370	COG3314	Sporulation integral membrane protein YlbJ
JF380_RS01395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JF380_RS01425	COG3037	sugar-specific permease SgaT UlaA
JF380_RS01435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JF380_RS01440	COG3711	transcriptional antiterminator
JF380_RS01460	COG2271	Major facilitator Superfamily
JF380_RS01465	COG0346	lactoylglutathione lyase activity
JF380_RS01470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JF380_RS01475	COG0431	NADPH-dependent FMN reductase
JF380_RS01485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JF380_RS01500	COG0672	)-iron permease
JF380_RS01505	COG0805	protein transport
JF380_RS01510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JF380_RS01520	COG1476	TRANSCRIPTIONal
JF380_RS01530	COG1131	(ABC) transporter
JF380_RS01560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JF380_RS01560	COG0646	methionine synthase
JF380_RS01565	COG0626	cystathionine gamma-synthase activity
JF380_RS01570	COG0626	cystathionine gamma-synthase activity
JF380_RS01575	COG1475	DNA binding
JF380_RS01580	COG0668	transmembrane transport
JF380_RS01585	COG4481	Protein conserved in bacteria
JF380_RS01590	COG0012	GTP binding
JF380_RS01710	COG3728	DNA packaging
JF380_RS01710	COG5484	DNA packaging
JF380_RS01805	COG1823	symporter activity
JF380_RS01835	COG2233	PERMEase
JF380_RS01900	COG1683	Conserved Protein
JF380_RS01910	COG3759	membrane
JF380_RS02045	COG0523	cobalamin synthesis protein
JF380_RS02070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JF380_RS02080	COG5609	conserved protein (DUF2294)
JF380_RS02095	COG1647	Serine aminopeptidase, S33
JF380_RS02105	COG0733	neurotransmitter:sodium symporter activity
JF380_RS02110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JF380_RS02115	COG0626	cystathionine gamma-synthase activity
JF380_RS02125	COG2011	ABC-type metal ion transport system permease component
JF380_RS02130	COG1464	Belongs to the NlpA lipoprotein family
JF380_RS02165	COG0583	DNA-binding transcription factor activity
JF380_RS02170	COG0070	glutamate synthase
JF380_RS02170	COG0069	glutamate synthase activity
JF380_RS02170	COG0067	glutamate synthase
JF380_RS02175	COG0493	'glutamate synthase
JF380_RS02190	COG0366	Alpha amylase catalytic
JF380_RS02195	COG2188	Transcriptional regulator
JF380_RS02215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JF380_RS02250	COG1982	Orn Lys Arg decarboxylase major
JF380_RS02260	COG3870	Protein conserved in bacteria
JF380_RS02265	COG0470	DNA polymerase III
JF380_RS02270	COG1774	PSP1 C-terminal conserved region
JF380_RS02280	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JF380_RS02290	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JF380_RS02300	COG0084	hydrolase, TatD family'
JF380_RS02305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JF380_RS02315	COG4466	Protein conserved in bacteria
JF380_RS02325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JF380_RS02330	COG0251	oxidation-reduction process
JF380_RS02370	COG2244	polysaccharide biosynthetic process
JF380_RS02375	COG3956	TIGRFAM MazG family protein
JF380_RS02380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JF380_RS02390	COG1098	S1 RNA binding domain
JF380_RS02405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JF380_RS02430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JF380_RS02520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JF380_RS02535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JF380_RS02545	COG3880	PFAM UvrB UvrC protein
JF380_RS02560	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JF380_RS02565	COG4956	integral membrane protein (PIN domain superfamily)
JF380_RS02585	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JF380_RS02640	COG2813	Specifically methylates the guanine in position
JF380_RS02680	COG1473	amidohydrolase
JF380_RS02710	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JF380_RS02715	COG1428	Deoxynucleoside kinase
JF380_RS02720	COG1428	Deoxynucleoside kinase
JF380_RS02730	COG0561	phosphatase activity
JF380_RS02765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JF380_RS02870	COG0095	Lipoate-protein ligase
JF380_RS02875	COG0083	homoserine kinase activity
JF380_RS02895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JF380_RS02985	COG0667	Aldo Keto reductase
JF380_RS02990	COG0655	NAD(P)H dehydrogenase (quinone) activity
JF380_RS03000	COG1078	dGTPase activity
JF380_RS03035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JF380_RS03040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF380_RS03090	COG4974	Belongs to the 'phage' integrase family
JF380_RS03135	COG0803	Belongs to the bacterial solute-binding protein 9 family
JF380_RS03140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JF380_RS03145	COG1121	(ABC) transporter
JF380_RS03150	COG1321	iron dependent repressor
JF380_RS03160	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JF380_RS03170	COG1682	transport, permease protein
JF380_RS03175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JF380_RS03185	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JF380_RS03190	COG1686	Belongs to the peptidase S11 family
JF380_RS03195	COG1132	(ABC) transporter
JF380_RS03200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JF380_RS03210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JF380_RS03215	COG1120	ATPase activity
JF380_RS03220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF380_RS03225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF380_RS03230	COG2376	Dihydroxyacetone kinase
JF380_RS03240	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JF380_RS03250	COG3949	Membrane
JF380_RS03270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JF380_RS03285	COG1136	(ABC) transporter
JF380_RS03290	COG0577	efflux transmembrane transporter activity
JF380_RS03295	COG1392	Phosphate transport regulator
JF380_RS03300	COG0306	phosphate transporter
JF380_RS03305	COG3942	CHAP domain
JF380_RS03305	COG1388	LysM domain
JF380_RS03345	COG0583	DNA-binding transcription factor activity
JF380_RS03350	COG2814	Major facilitator Superfamily
JF380_RS03355	COG2839	Protein conserved in bacteria
JF380_RS03385	COG1611	Belongs to the LOG family
JF380_RS03405	COG4988	ABC transporter
JF380_RS03410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JF380_RS03420	COG0523	cobalamin synthesis protein
JF380_RS03425	COG4989	oxidoreductase activity
JF380_RS03435	COG0471	metal ion transport
JF380_RS03440	COG0415	Belongs to the DNA photolyase family
JF380_RS03470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JF380_RS03475	COG1349	DNA-binding transcription factor activity
JF380_RS03480	COG1105	Belongs to the carbohydrate kinase PfkB family
JF380_RS03485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JF380_RS03485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JF380_RS03485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JF380_RS03490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JF380_RS03495	COG1253	flavin adenine dinucleotide binding
JF380_RS03500	COG0656	L-ascorbic acid biosynthetic process
JF380_RS03505	COG0463	Glycosyl transferase, family 2
JF380_RS03540	COG0720	synthase
JF380_RS03550	COG0512	Glutamine amidotransferase of anthranilate synthase
JF380_RS03550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JF380_RS03555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JF380_RS03585	COG0488	(ABC) transporter
JF380_RS03590	COG0514	ATP-dependent DNA helicase (RecQ)
JF380_RS03595	COG1125	glycine betaine transport
JF380_RS03595	COG0517	IMP dehydrogenase activity
JF380_RS03600	COG1174	glycine betaine transport
JF380_RS03625	COG3104	oligopeptide transport
JF380_RS03645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JF380_RS03650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JF380_RS03660	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF380_RS03665	COG4605	iron ion homeostasis
JF380_RS03670	COG4604	ABC transporter, ATP-binding protein
JF380_RS03675	COG4607	ABC-type enterochelin transport system periplasmic component
JF380_RS03730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JF380_RS03735	COG1739	Uncharacterized protein family UPF0029
JF380_RS03745	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JF380_RS03750	COG1040	competence protein
JF380_RS03780	COG1388	LysM domain
JF380_RS03780	COG3942	CHAP domain
JF380_RS03835	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JF380_RS03895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JF380_RS03900	COG1647	Serine aminopeptidase, S33
JF380_RS03905	COG0557	exoribonuclease II activity
JF380_RS04000	COG5484	DNA packaging
JF380_RS04000	COG3728	DNA packaging
JF380_RS04100	COG1278	Cold shock
JF380_RS04140	COG0406	alpha-ribazole phosphatase activity
JF380_RS04145	COG1279	arginine transmembrane transporter activity
JF380_RS04170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JF380_RS04175	COG1393	Belongs to the ArsC family
JF380_RS04185	COG3878	Protein conserved in bacteria
JF380_RS04190	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JF380_RS04205	COG2011	ABC-type metal ion transport system permease component
JF380_RS04210	COG1464	Belongs to the NlpA lipoprotein family
JF380_RS04225	COG0396	ATPase activity
JF380_RS04230	COG0719	Fe-S assembly protein
JF380_RS04240	COG0822	iron-sulfur transferase activity
JF380_RS04280	COG3646	Phage regulatory protein
JF380_RS04280	COG3645	SOS response
JF380_RS04355	COG1484	DNA-dependent DNA replication
JF380_RS04395	COG0756	dUTP diphosphatase activity
JF380_RS04555	COG1388	LysM domain
JF380_RS04555	COG0860	N-Acetylmuramoyl-L-alanine amidase
JF380_RS04595	COG1253	flavin adenine dinucleotide binding
JF380_RS04605	COG1801	Protein of unknown function DUF72
JF380_RS04610	COG0730	response to heat
JF380_RS04625	COG4470	Protein conserved in bacteria
JF380_RS04635	COG2445	Protein of unknown function DUF86
JF380_RS04665	COG1696	Membrane protein involved in D-alanine export
JF380_RS04675	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JF380_RS04680	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JF380_RS04685	COG4837	Protein of unknown function (DUF1462)
JF380_RS04690	COG1252	NADH dehydrogenase
JF380_RS04700	COG0316	Belongs to the HesB IscA family
JF380_RS04710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JF380_RS04715	COG2056	Na+-H+ antiporter family
JF380_RS04720	COG2050	protein possibly involved in aromatic compounds catabolism
JF380_RS04775	COG1098	S1 RNA binding domain
JF380_RS04780	COG1902	pentaerythritol trinitrate reductase activity
JF380_RS04795	COG0584	glycerophosphoryl diester phosphodiesterase
JF380_RS04815	COG0398	Pfam SNARE associated Golgi protein
JF380_RS04860	COG0561	phosphatase activity
JF380_RS04900	COG1881	PFAM PEBP family protein
JF380_RS04930	COG0601	transmembrane transport
JF380_RS04935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JF380_RS04940	COG0444	Belongs to the ABC transporter superfamily
JF380_RS04945	COG4608	Belongs to the ABC transporter superfamily
JF380_RS04950	COG4166	transmembrane transport
JF380_RS04955	COG0747	negative chemotaxis
JF380_RS04960	COG0444	Belongs to the ABC transporter superfamily
JF380_RS04965	COG4608	Belongs to the ABC transporter superfamily
JF380_RS04970	COG0601	transmembrane transport
JF380_RS04975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JF380_RS05000	COG1164	Oligoendopeptidase f
JF380_RS05010	COG2346	COG2346, Truncated hemoglobins
JF380_RS05025	COG2357	RelA SpoT domain protein
JF380_RS05035	COG0564	pseudouridine synthase activity
JF380_RS05040	COG2239	Acts as a magnesium transporter
JF380_RS05045	COG0569	domain protein
JF380_RS05045	COG0475	glutathione-regulated potassium exporter activity
JF380_RS05055	COG0628	permease
JF380_RS05060	COG1115	amino acid carrier protein
JF380_RS05100	COG0861	Integral membrane protein TerC family
JF380_RS05110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JF380_RS05115	COG0737	Belongs to the 5'-nucleotidase family
JF380_RS05130	COG4903	ComK protein
JF380_RS05145	COG4873	Protein conserved in bacteria
JF380_RS05200	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JF380_RS05210	COG2314	TM2 domain
JF380_RS05215	COG0456	acetyltransferase
JF380_RS05220	COG1575	Belongs to the MenA family. Type 1 subfamily
JF380_RS05225	COG1169	isochorismate synthase
JF380_RS05235	COG2267	carboxylic ester hydrolase activity
JF380_RS05260	COG0436	Aminotransferase
JF380_RS05265	COG3594	Acyltransferase
JF380_RS05295	COG1316	TRANSCRIPTIONal
JF380_RS05340	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JF380_RS05355	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JF380_RS05395	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JF380_RS05400	COG4172	Belongs to the ABC transporter superfamily
JF380_RS05405	COG4721	ABC-type cobalt transport system, permease component
JF380_RS05415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JF380_RS05440	COG1271	oxidase subunit
JF380_RS05445	COG1294	oxidase, subunit
JF380_RS05450	COG0569	domain protein
JF380_RS05515	COG1176	ABC-type spermidine putrescine transport system, permease component I
JF380_RS05520	COG1177	transmembrane transport
JF380_RS05525	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JF380_RS05550	COG0483	inositol monophosphate 1-phosphatase activity
JF380_RS05560	COG1217	gtp-binding protein TYPA
JF380_RS05570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JF380_RS05580	COG0772	Belongs to the SEDS family
JF380_RS05610	COG3679	Belongs to the UPF0342 family
JF380_RS05630	COG0742	ribosomal rna small subunit methyltransferase
JF380_RS05685	COG4509	Sortase family
JF380_RS05700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JF380_RS05730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JF380_RS05730	COG1796	DNA polymerase
JF380_RS05755	COG2009	succinate dehydrogenase
JF380_RS05760	COG1053	succinate dehydrogenase
JF380_RS05765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JF380_RS05870	COG1288	antiporter activity
JF380_RS05910	COG1011	Hydrolase
JF380_RS05935	COG4839	cell division protein FtsL
JF380_RS05940	COG0768	penicillin binding
JF380_RS05955	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JF380_RS05960	COG0849	cell division
JF380_RS05975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JF380_RS05985	COG0762	integral membrane protein
JF380_RS05990	COG2302	S4 RNA-binding domain
JF380_RS05995	COG3599	regulation of cell shape
JF380_RS06005	COG2514	catechol 2,3-dioxygenase activity
JF380_RS06020	COG0564	pseudouridine synthase activity
JF380_RS06030	COG2233	PERMEase
JF380_RS06075	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JF380_RS06090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JF380_RS06095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JF380_RS06105	COG2314	TM2 domain
JF380_RS06120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JF380_RS06120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JF380_RS06130	COG0631	protein serine/threonine phosphatase activity
JF380_RS06145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JF380_RS06160	COG1302	Protein conserved in bacteria
JF380_RS06205	COG1196	nuclear chromosome segregation
JF380_RS06210	COG0552	protein localization to endoplasmic reticulum
JF380_RS06220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JF380_RS06280	COG0758	DNA mediated transformation
JF380_RS06375	COG0195	Participates in both transcription termination and antitermination
JF380_RS06380	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JF380_RS06405	COG0196	riboflavin kinase activity
JF380_RS06430	COG2188	Transcriptional regulator
JF380_RS06435	COG0612	Peptidase, M16
JF380_RS06440	COG0612	Peptidase, M16
JF380_RS06445	COG0300	oxidoreductase activity
JF380_RS06465	COG1546	Belongs to the CinA family
JF380_RS06465	COG1058	Belongs to the CinA family
JF380_RS06485	COG1692	metallophosphoesterase
JF380_RS06490	COG0674	pyruvate-flavodoxin oxidoreductase activity
JF380_RS06490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JF380_RS06495	COG1013	pyruvate-flavodoxin oxidoreductase activity
JF380_RS06530	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JF380_RS06535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JF380_RS06560	COG1923	regulation of RNA biosynthetic process
JF380_RS06570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JF380_RS06575	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JF380_RS06580	COG0789	Transcriptional regulator
JF380_RS06685	COG1131	(ABC) transporter
JF380_RS06700	COG2197	response regulator
JF380_RS06710	COG1525	nuclease
JF380_RS06725	COG0527	aspartate kinase activity
JF380_RS06730	COG0460	homoserine dehydrogenase
JF380_RS06735	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JF380_RS06760	COG0833	amino acid
JF380_RS06785	COG2340	Cysteine-rich secretory protein family
JF380_RS06820	COG4846	Membrane protein involved in cytochrome C biogenesis
JF380_RS06840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JF380_RS06850	COG0824	Thioesterase
JF380_RS06870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JF380_RS06875	COG1115	amino acid carrier protein
JF380_RS06890	COG0628	permease
JF380_RS06915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JF380_RS06925	COG1363	Peptidase, m42
JF380_RS06930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JF380_RS06935	COG0512	Glutamine amidotransferase of anthranilate synthase
JF380_RS06975	COG0561	phosphatase activity
JF380_RS07020	COG0704	Plays a role in the regulation of phosphate uptake
JF380_RS07030	COG0581	inorganic phosphate transmembrane transporter activity
JF380_RS07035	COG0573	inorganic phosphate transmembrane transporter activity
JF380_RS07055	COG0488	(ABC) transporter
JF380_RS07060	COG0527	aspartate kinase activity
JF380_RS07065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JF380_RS07135	COG4548	von Willebrand factor, type A
JF380_RS07140	COG0714	Associated with various cellular activities
JF380_RS07185	COG0671	phosphoesterase, PA-phosphatase related
JF380_RS07265	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JF380_RS07290	COG0531	amino acid
JF380_RS07305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JF380_RS07310	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JF380_RS07325	COG0116	Belongs to the methyltransferase superfamily
JF380_RS07360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JF380_RS07360	COG4499	WXG100 protein secretion system (Wss), protein YukC
JF380_RS07370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JF380_RS07375	COG3935	DnaD domain protein
JF380_RS07400	COG0438	transferase activity, transferring glycosyl groups
JF380_RS07405	COG1694	Mazg nucleotide pyrophosphohydrolase
JF380_RS07410	COG2738	Putative neutral zinc metallopeptidase
JF380_RS07415	COG4347	Protein of unknown function (DUF1405)
JF380_RS07455	COG0142	geranyltranstransferase activity
JF380_RS07510	COG0492	ferredoxin-NADP+ reductase activity
JF380_RS07525	COG0514	ATP-dependent DNA helicase (RecQ)
JF380_RS07535	COG1141	Ferredoxin
JF380_RS07575	COG5002	protein histidine kinase activity
JF380_RS07580	COG0745	RESPONSE REGULATOR receiver
JF380_RS07585	COG1187	pseudouridine synthase activity
JF380_RS07610	COG0735	belongs to the Fur family
JF380_RS07615	COG0494	nUDIX hydrolase
JF380_RS07620	COG0667	Aldo Keto reductase
JF380_RS07630	COG4221	oxidoreductase activity
JF380_RS07645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JF380_RS07655	COG0366	Alpha amylase catalytic
JF380_RS07660	COG1609	Transcriptional regulator
JF380_RS07685	COG2195	Cleaves the N-terminal amino acid of tripeptides
JF380_RS07695	COG4129	membrane
JF380_RS07705	COG0508	dehydrogenase complex catalyzes the overall conversion of
JF380_RS07710	COG0022	dehydrogenase e1 component
JF380_RS07715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JF380_RS07720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JF380_RS07725	COG0497	DNA recombination
JF380_RS07755	COG1302	Protein conserved in bacteria
JF380_RS07760	COG0439	Biotin carboxylase
JF380_RS07765	COG0511	ligase activity, forming carbon-carbon bonds
JF380_RS07775	COG0006	proline dipeptidase activity
JF380_RS07790	COG0095	Lipoate-protein ligase
JF380_RS07795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JF380_RS07840	COG4537	Required for transformation and DNA binding
JF380_RS07845	COG1459	type II secretion system
JF380_RS07850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JF380_RS07855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JF380_RS07860	COG0011	TIGRFAM Protein of
JF380_RS07865	COG1940	carbohydrate kinase activity
JF380_RS07870	COG4483	Protein conserved in bacteria
JF380_RS07880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JF380_RS07890	COG0768	penicillin binding
JF380_RS07905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JF380_RS07910	COG1121	(ABC) transporter
JF380_RS07920	COG0513	Belongs to the DEAD box helicase family
JF380_RS07930	COG2384	SAM-dependent methyltransferase
JF380_RS07950	COG0517	IMP dehydrogenase activity
JF380_RS07970	COG0295	cytidine deaminase activity
JF380_RS07985	COG1702	phosphate starvation-inducible protein PhoH
JF380_RS08000	COG1030	water channel activity
JF380_RS08010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JF380_RS08015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JF380_RS08045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JF380_RS08060	COG1466	dna polymerase III delta subunit
JF380_RS08065	COG0658	competence protein
JF380_RS08065	COG2333	competence protein COMEC
JF380_RS08070	COG2131	deaminase
JF380_RS08075	COG2183	response to ionizing radiation
JF380_RS08080	COG2226	methyltransferase
JF380_RS08085	COG0799	negative regulation of ribosome biogenesis
JF380_RS08090	COG1713	HD superfamily hydrolase involved in NAD metabolism
JF380_RS08100	COG1534	Rna-binding protein
JF380_RS08110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JF380_RS08115	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JF380_RS08140	COG1914	H( )-stimulated, divalent metal cation uptake system
JF380_RS08150	COG0439	Biotin carboxylase
JF380_RS08155	COG0511	ligase activity, forming carbon-carbon bonds
JF380_RS08160	COG1984	allophanate hydrolase subunit 2
JF380_RS08165	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JF380_RS08180	COG0826	peptidase U32
JF380_RS08185	COG0826	peptidase U32
JF380_RS08215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JF380_RS08230	COG1104	cysteine desulfurase activity
JF380_RS08235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JF380_RS08245	COG3237	CsbD-like
JF380_RS08250	COG1959	2 iron, 2 sulfur cluster binding
JF380_RS08255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JF380_RS08260	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JF380_RS08305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JF380_RS08305	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JF380_RS08310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JF380_RS08310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JF380_RS08315	COG1862	Preprotein translocase
JF380_RS08355	COG2868	ribosomal protein
JF380_RS08400	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JF380_RS08405	COG0285	dihydrofolate synthase activity
JF380_RS08415	COG2818	Glycosylase
JF380_RS08450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JF380_RS08485	COG4112	unkown
JF380_RS08505	COG0833	amino acid
JF380_RS08520	COG1484	DNA-dependent DNA replication
JF380_RS08555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JF380_RS08555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JF380_RS08565	COG5002	protein histidine kinase activity
JF380_RS08570	COG0745	RESPONSE REGULATOR receiver
JF380_RS08580	COG0372	Belongs to the citrate synthase family
JF380_RS08585	COG1113	amino acid transport
JF380_RS08610	COG0281	malic enzyme
JF380_RS08620	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JF380_RS08625	COG4109	DRTGG domain
JF380_RS08665	COG0827	DNA restriction-modification system
JF380_RS08685	COG1104	cysteine desulfurase activity
JF380_RS08700	COG1956	GAF domain-containing protein
JF380_RS08710	COG0584	glycerophosphoryl diester phosphodiesterase
JF380_RS08715	COG1764	response to oxidative stress
JF380_RS08720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JF380_RS08725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JF380_RS08740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JF380_RS08740	COG1263	PTS System
JF380_RS08745	COG0204	Acyl-transferase
JF380_RS08750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JF380_RS08780	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JF380_RS08785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JF380_RS08790	COG0454	-acetyltransferase
JF380_RS08810	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JF380_RS08810	COG1605	Chorismate mutase
JF380_RS08835	COG1674	ftsk spoiiie
JF380_RS08840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JF380_RS08850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JF380_RS08855	COG1363	Peptidase, m42
JF380_RS08865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JF380_RS08875	COG0510	thiamine kinase activity
JF380_RS08895	COG1187	pseudouridine synthase activity
JF380_RS08900	COG2244	polysaccharide biosynthetic process
JF380_RS08905	COG2081	HI0933 family
JF380_RS08925	COG2814	Major facilitator Superfamily
JF380_RS08930	COG1242	4 iron, 4 sulfur cluster binding
JF380_RS08935	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JF380_RS08945	COG2267	carboxylic ester hydrolase activity
JF380_RS08975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JF380_RS08975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JF380_RS08995	COG5632	N-Acetylmuramoyl-L-alanine amidase
JF380_RS08995	COG3266	domain, Protein
JF380_RS08995	COG4193	domain, Protein
JF380_RS09025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JF380_RS09050	COG0656	L-ascorbic acid biosynthetic process
JF380_RS09070	COG1506	peptidase
JF380_RS09280	COG0860	N-Acetylmuramoyl-L-alanine amidase
JF380_RS09280	COG1388	LysM domain
JF380_RS09330	COG5412	phage tail tape measure protein
JF380_RS09330	COG3953	SLT domain
JF380_RS09440	COG0756	dUTP diphosphatase activity
JF380_RS09510	COG0305	Participates in initiation and elongation during chromosome replication
JF380_RS09605	COG0582	viral genome integration into host DNA
JF380_RS09655	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JF380_RS09685	COG1131	(ABC) transporter
JF380_RS09690	COG0537	adenosine 5'-monophosphoramidase activity
JF380_RS09720	COG0420	3'-5' exonuclease activity
JF380_RS09745	COG2197	response regulator
JF380_RS09750	COG4585	Histidine kinase
JF380_RS09750	COG2203	Gaf domain
JF380_RS09755	COG0564	pseudouridine synthase activity
JF380_RS09785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JF380_RS09790	COG1126	abc transporter atp-binding protein
JF380_RS09795	COG0765	amino acid transport
JF380_RS09965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JF380_RS09970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JF380_RS09980	COG4129	membrane
JF380_RS10005	COG1988	membrane-bound metal-dependent
JF380_RS10015	COG1134	teichoic acid transport
JF380_RS10015	COG1388	LysM domain
JF380_RS10045	COG0535	radical SAM domain protein
JF380_RS10050	COG1607	acyl-coa hydrolase
JF380_RS10055	COG2309	aminopeptidase activity
JF380_RS10075	COG1295	ribonuclease BN
JF380_RS10190	COG4851	CamS sex pheromone cAM373 precursor
JF380_RS10210	COG4496	protein, YerC YecD
JF380_RS10245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JF380_RS10255	COG0077	Prephenate dehydratase
JF380_RS10265	COG0471	metal ion transport
JF380_RS10275	COG1335	isochorismatase
JF380_RS10290	COG1012	belongs to the aldehyde dehydrogenase family
JF380_RS10345	COG1131	(ABC) transporter
JF380_RS10360	COG1725	Transcriptional regulator
JF380_RS10410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JF380_RS10475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JF380_RS10480	COG1621	beta-fructofuranosidase activity
JF380_RS10485	COG1609	Transcriptional regulator
JF380_RS10490	COG0004	ammonium transporteR
JF380_RS10495	COG0425	Belongs to the sulfur carrier protein TusA family
JF380_RS10500	COG2391	methyltransferase activity
JF380_RS10510	COG0488	(ABC) transporter
JF380_RS10525	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JF380_RS10535	COG0456	acetyltransferase
JF380_RS10540	COG1214	PFAM Peptidase M22, glycoprotease
JF380_RS10545	COG0802	atpase or kinase
JF380_RS10560	COG0028	Belongs to the TPP enzyme family
JF380_RS10630	COG2183	response to ionizing radiation
JF380_RS10635	COG1191	sigma factor activity
JF380_RS10645	COG1366	Belongs to the anti-sigma-factor antagonist family
JF380_RS10650	COG2208	phosphoserine phosphatase activity
JF380_RS10680	COG3428	Bacterial PH domain
JF380_RS10710	COG2205	protein histidine kinase activity
JF380_RS10715	COG0745	RESPONSE REGULATOR receiver
JF380_RS10725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JF380_RS10735	COG0772	Belongs to the SEDS family
JF380_RS10750	COG1937	Protein conserved in bacteria
JF380_RS10760	COG1418	mRNA catabolic process
JF380_RS10795	COG0629	single-stranded DNA binding
JF380_RS10870	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JF380_RS10895	COG0009	L-threonylcarbamoyladenylate synthase
JF380_RS10900	COG2890	protein-(glutamine-N5) methyltransferase activity
JF380_RS10920	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JF380_RS10960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JF380_RS11005	COG0813	purine-nucleoside phosphorylase activity
JF380_RS11010	COG0783	Belongs to the Dps family
JF380_RS11030	COG1482	cell wall glycoprotein biosynthetic process
JF380_RS11035	COG0702	epimerase
JF380_RS11040	COG0640	Transcriptional regulator
JF380_RS11065	COG0561	phosphatase activity
JF380_RS11070	COG1119	ATPase activity
JF380_RS11085	COG3711	transcriptional antiterminator
JF380_RS11115	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JF380_RS11175	COG0489	protein tyrosine kinase activity
JF380_RS11195	COG1272	protein, Hemolysin III
JF380_RS11205	COG1988	membrane-bound metal-dependent
JF380_RS11215	COG3314	Sporulation integral membrane protein YlbJ
JF380_RS11220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF380_RS11225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF380_RS11230	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JF380_RS11240	COG3457	Alanine racemase
JF380_RS11245	COG4264	IucA IucC family
JF380_RS11250	COG2814	Major facilitator Superfamily
JF380_RS11275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JF380_RS11285	COG2130	NADP-dependent
JF380_RS11335	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JF380_RS11355	COG0656	L-ascorbic acid biosynthetic process
JF380_RS11360	COG0789	Transcriptional regulator
JF380_RS11370	COG5492	domain, Protein
JF380_RS11380	COG3527	Alpha-acetolactate decarboxylase
JF380_RS11385	COG0028	Belongs to the TPP enzyme family
JF380_RS11465	COG0201	protein transport
JF380_RS11580	COG2252	PERMEase
JF380_RS11630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JF380_RS11690	COG1763	Mo-molybdopterin cofactor biosynthetic process
JF380_RS11710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JF380_RS11715	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JF380_RS11720	COG4149	molybdate abc transporter
JF380_RS11725	COG0725	ABC transporter, periplasmic molybdate-binding protein
JF380_RS11740	COG1268	BioY protein
JF380_RS11755	COG1960	acyl-CoA dehydrogenase activity
JF380_RS11760	COG4413	Urea transporter
JF380_RS11820	COG3942	CHAP domain
JF380_RS11830	COG1757	Na H antiporter
JF380_RS11845	COG3942	CHAP domain
JF380_RS11915	COG1113	amino acid transport
JF380_RS11935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JF380_RS11940	COG0385	Bile acid
JF380_RS11950	COG1263	PTS System
JF380_RS11950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JF380_RS11955	COG1737	Transcriptional regulator
JF380_RS11975	COG1028	Short-chain dehydrogenase reductase Sdr
JF380_RS11980	COG1473	amidohydrolase
JF380_RS11995	COG0583	DNA-binding transcription factor activity
JF380_RS12015	COG2258	MOSC domain
JF380_RS12035	COG1668	transmembrane transport
JF380_RS12040	COG4152	abc transporter atp-binding protein
JF380_RS12045	COG3152	Membrane
JF380_RS12055	COG0786	glutamate:sodium symporter activity
JF380_RS12065	COG0598	Magnesium transport protein CorA
JF380_RS12080	COG0657	acetylesterase activity
JF380_RS12090	COG2814	Major facilitator Superfamily
JF380_RS12095	COG1566	PFAM secretion protein HlyD family protein
JF380_RS12105	COG2814	Major facilitator Superfamily
JF380_RS12165	COG1620	l-lactate permease
JF380_RS12185	COG0604	alcohol dehydrogenase
JF380_RS12210	COG1511	domain protein
JF380_RS12225	COG1263	PTS System
JF380_RS12225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JF380_RS12240	COG3871	stress protein (general stress protein 26)
JF380_RS12280	COG0789	Transcriptional regulator
JF380_RS12300	COG2181	nitrate reductase activity
JF380_RS12310	COG1140	nitrate reductase beta subunit
JF380_RS12315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JF380_RS12325	COG2146	nitrite reductase [NAD(P)H] activity
JF380_RS12330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JF380_RS12340	COG0454	-acetyltransferase
JF380_RS12345	COG2116	formate transmembrane transporter activity
JF380_RS12360	COG0803	Belongs to the bacterial solute-binding protein 9 family
JF380_RS12360	COG3443	Belongs to the bacterial solute-binding protein 9 family
JF380_RS12400	COG1126	abc transporter atp-binding protein
JF380_RS12405	COG0765	amino acid transport
JF380_RS12410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JF380_RS12415	COG2814	Major facilitator Superfamily
JF380_RS12430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JF380_RS12470	COG0156	8-amino-7-oxononanoate synthase activity
JF380_RS12480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JF380_RS12485	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JF380_RS12495	COG1132	(ABC) transporter
JF380_RS12500	COG2375	cellular response to nickel ion
JF380_RS12500	COG1132	(ABC) transporter
JF380_RS12515	COG1929	Belongs to the glycerate kinase type-1 family
JF380_RS12525	COG2814	Major facilitator Superfamily
JF380_RS12545	COG1113	amino acid transport
JF380_RS12555	COG0531	amino acid
JF380_RS12560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JF380_RS12570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JF380_RS12580	COG1174	glycine betaine transport
JF380_RS12590	COG1174	glycine betaine transport
JF380_RS12600	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JF380_RS12605	COG0531	amino acid
JF380_RS12610	COG2272	Belongs to the type-B carboxylesterase lipase family
JF380_RS12615	COG2814	Major facilitator Superfamily
JF380_RS12620	COG0390	transport system, permease component
JF380_RS12625	COG4619	ABC transporter
JF380_RS12630	COG1363	Peptidase, m42
JF380_RS12645	COG4808	Protein conserved in bacteria
JF380_RS12650	COG0069	glutamate synthase activity
JF380_RS12670	COG0444	Belongs to the ABC transporter superfamily
JF380_RS12675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JF380_RS12710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JF380_RS12715	COG1028	Short-chain dehydrogenase reductase Sdr
JF380_RS12725	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JF380_RS12855	COG1802	Transcriptional regulator
JF380_RS12860	COG0789	Transcriptional regulator
JF380_RS12865	COG2357	RelA SpoT domain protein
JF380_RS12870	COG4876	unkown
JF380_RS12880	COG2271	Major facilitator Superfamily
JF380_RS12885	COG0586	Pfam SNARE associated Golgi protein
JF380_RS12890	COG1131	(ABC) transporter
JF380_RS12905	COG3949	Membrane
JF380_RS12910	COG0400	carboxylic ester hydrolase activity
JF380_RS12915	COG0346	lactoylglutathione lyase activity
JF380_RS12920	COG1846	Transcriptional regulator
JF380_RS12945	COG0561	phosphatase activity
JF380_RS12960	COG3764	Sortase (surface protein transpeptidase)
JF380_RS12980	COG1760	l-serine dehydratase
JF380_RS12985	COG1760	l-serine dehydratase
JF380_RS13000	COG0697	spore germination
JF380_RS13005	COG0657	acetylesterase activity
JF380_RS13025	COG0028	Belongs to the TPP enzyme family
JF380_RS13040	COG0583	DNA-binding transcription factor activity
JF380_RS13050	COG3942	CHAP domain
JF380_RS13060	COG3425	synthase
JF380_RS13065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JF380_RS13135	COG0436	Aminotransferase
JF380_RS13165	COG3942	CHAP domain
JF380_RS13170	COG2755	lipolytic protein G-D-S-L family
JF380_RS13170	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JF380_RS13240	COG0596	Alpha beta hydrolase
JF380_RS13275	COG3001	Fructosamine kinase
JF380_RS13280	COG0167	dihydroorotate dehydrogenase activity
JF380_RS13330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JF380_RS13335	COG3527	Alpha-acetolactate decarboxylase
JF380_RS13345	COG0531	amino acid
JF380_RS13375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JF380_RS13395	COG1012	belongs to the aldehyde dehydrogenase family
JF380_RS13405	COG1510	regulation of RNA biosynthetic process
JF380_RS13410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JF380_RS13435	COG2851	Citrate transporter
JF380_RS13445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JF380_RS13455	COG0386	Belongs to the glutathione peroxidase family
JF380_RS13475	COG1136	(ABC) transporter
JF380_RS13480	COG2205	protein histidine kinase activity
JF380_RS13485	COG0745	RESPONSE REGULATOR receiver
JF380_RS13495	COG1785	Belongs to the alkaline phosphatase family
JF380_RS13505	COG1846	Transcriptional regulator
JF380_RS13550	COG1438	arginine binding
JF380_RS13570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JF380_RS13570	COG3711	transcriptional antiterminator
JF380_RS13575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JF380_RS13575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JF380_RS13575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JF380_RS13580	COG1482	cell wall glycoprotein biosynthetic process
JF380_RS13590	COG1705	Flagellar rod assembly protein muramidase FlgJ
JF380_RS13590	COG3942	CHAP domain
JF380_RS13595	COG3433	isochorismatase activity
JF380_RS13595	COG1535	isochorismatase
JF380_RS13610	COG0438	transferase activity, transferring glycosyl groups
JF380_RS13625	COG1073	alpha beta
JF380_RS13645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JF380_RS13665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JF380_RS13725	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JF380_RS13755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JF380_RS13835	COG0471	metal ion transport
JF380_RS13840	COG2962	Rard protein
JF380_RS13850	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JF380_RS13865	COG1136	(ABC) transporter
JF380_RS13870	COG0577	efflux transmembrane transporter activity
JF380_RS13895	COG1404	Belongs to the peptidase S8 family
JF380_RS13910	COG1278	Cold shock
JF380_RS13930	COG1475	DNA binding
JF380_RS13965	COG1192	Involved in chromosome partitioning
JF380_RS14035	COG1266	CAAX protease self-immunity
JF380_RS14135	COG1705	Flagellar rod assembly protein muramidase FlgJ
JF380_RS14135	COG3942	CHAP domain
