locus-tag	class	description
JF379_RS00015	COG2501	S4 domain
JF379_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JF379_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JF379_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JF379_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JF379_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
JF379_RS00110	COG4863	YycH protein
JF379_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JF379_RS00125	COG0737	Belongs to the 5'-nucleotidase family
JF379_RS00145	COG2801	Transposase and inactivated derivatives
JF379_RS00165	COG0456	acetyltransferase
JF379_RS00180	COG0730	response to heat
JF379_RS00185	COG1937	Protein conserved in bacteria
JF379_RS00190	COG2210	Belongs to the sulfur carrier protein TusA family
JF379_RS00195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JF379_RS00230	COG0655	NAD(P)H dehydrogenase (quinone) activity
JF379_RS00265	COG0823	Involved in the tonB-independent uptake of proteins
JF379_RS00300	COG1473	amidohydrolase
JF379_RS00310	COG1283	sodium-dependent phosphate transmembrane transporter activity
JF379_RS00315	COG4716	Myosin-crossreactive antigen
JF379_RS00325	COG1620	l-lactate permease
JF379_RS00340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF379_RS00345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF379_RS00350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JF379_RS00360	COG2423	ornithine cyclodeaminase activity
JF379_RS00365	COG4264	IucA IucC family
JF379_RS00370	COG2814	Major facilitator Superfamily
JF379_RS00375	COG4264	IucA IucC family
JF379_RS00380	COG4264	IucA IucC family
JF379_RS00390	COG0019	diaminopimelate decarboxylase activity
JF379_RS00395	COG1475	DNA binding
JF379_RS00420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JF379_RS00425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JF379_RS00430	COG0438	transferase activity, transferring glycosyl groups
JF379_RS00460	COG0813	purine-nucleoside phosphorylase activity
JF379_RS00465	COG2814	Major facilitator Superfamily
JF379_RS00485	COG3639	organic phosphonate transmembrane transporter activity
JF379_RS00505	COG0737	Belongs to the 5'-nucleotidase family
JF379_RS00530	COG1454	alcohol dehydrogenase
JF379_RS00530	COG1012	belongs to the aldehyde dehydrogenase family
JF379_RS00555	COG1086	Polysaccharide biosynthesis protein
JF379_RS00565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JF379_RS00595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JF379_RS00605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JF379_RS00610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JF379_RS00620	COG2832	Protein of unknown function (DUF454)
JF379_RS00655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JF379_RS00665	COG5609	conserved protein (DUF2294)
JF379_RS00715	COG1114	Component of the transport system for branched-chain amino acids
JF379_RS00720	COG1335	isochorismatase
JF379_RS00725	COG3961	Belongs to the TPP enzyme family
JF379_RS00755	COG1737	Transcriptional regulator
JF379_RS00780	COG1136	(ABC) transporter
JF379_RS00785	COG0577	efflux transmembrane transporter activity
JF379_RS00785	COG1136	(ABC) transporter
JF379_RS00820	COG0601	transmembrane transport
JF379_RS00825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JF379_RS00835	COG0405	Gamma-glutamyltransferase
JF379_RS00855	COG3842	ATPase activity
JF379_RS00865	COG1175	transmembrane transport
JF379_RS00870	COG3833	ABC-type maltose transport systems, permease component
JF379_RS00875	COG0673	inositol 2-dehydrogenase activity
JF379_RS00880	COG0673	inositol 2-dehydrogenase activity
JF379_RS00890	COG1755	Isoprenylcysteine carboxyl methyltransferase
JF379_RS00945	COG0183	Belongs to the thiolase family
JF379_RS00955	COG1960	acyl-CoA dehydrogenase activity
JF379_RS00960	COG0318	PFAM AMP-dependent synthetase and ligase
JF379_RS00975	COG0747	negative chemotaxis
JF379_RS00980	COG3189	MarR family transcriptional regulator
JF379_RS01005	COG1263	PTS System
JF379_RS01005	COG2190	(PTS) system
JF379_RS01005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JF379_RS01010	COG1957	nucleoside hydrolase
JF379_RS01030	COG3414	Phosphotransferase system galactitol-specific IIB component
JF379_RS01035	COG3775	system Galactitol-specific IIC component
JF379_RS01040	COG1063	alcohol dehydrogenase
JF379_RS01050	COG1063	alcohol dehydrogenase
JF379_RS01060	COG1063	alcohol dehydrogenase
JF379_RS01065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JF379_RS01070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JF379_RS01080	COG1063	alcohol dehydrogenase
JF379_RS01085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JF379_RS01120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JF379_RS01125	COG1263	PTS System
JF379_RS01125	COG2190	(PTS) system
JF379_RS01125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JF379_RS01130	COG2723	6-phospho-beta-galactosidase activity
JF379_RS01135	COG2226	methyltransferase
JF379_RS01190	COG1131	(ABC) transporter
JF379_RS01210	COG3942	CHAP domain
JF379_RS01210	COG1388	LysM domain
JF379_RS01320	COG1114	Component of the transport system for branched-chain amino acids
JF379_RS01325	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JF379_RS01330	COG0577	efflux transmembrane transporter activity
JF379_RS01355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JF379_RS01360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JF379_RS01385	COG3314	Sporulation integral membrane protein YlbJ
JF379_RS01410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JF379_RS01440	COG3037	sugar-specific permease SgaT UlaA
JF379_RS01450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JF379_RS01455	COG3711	transcriptional antiterminator
JF379_RS01475	COG2271	Major facilitator Superfamily
JF379_RS01480	COG0346	lactoylglutathione lyase activity
JF379_RS01485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JF379_RS01490	COG0431	NADPH-dependent FMN reductase
JF379_RS01500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JF379_RS01515	COG0672	)-iron permease
JF379_RS01520	COG0805	protein transport
JF379_RS01525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JF379_RS01535	COG1476	TRANSCRIPTIONal
JF379_RS01545	COG1131	(ABC) transporter
JF379_RS01575	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JF379_RS01575	COG0646	methionine synthase
JF379_RS01580	COG0626	cystathionine gamma-synthase activity
JF379_RS01585	COG0626	cystathionine gamma-synthase activity
JF379_RS01590	COG1475	DNA binding
JF379_RS01595	COG0668	transmembrane transport
JF379_RS01600	COG4481	Protein conserved in bacteria
JF379_RS01605	COG0012	GTP binding
JF379_RS01725	COG5484	DNA packaging
JF379_RS01725	COG3728	DNA packaging
JF379_RS01820	COG1823	symporter activity
JF379_RS01850	COG2233	PERMEase
JF379_RS01865	COG0582	viral genome integration into host DNA
JF379_RS01990	COG1683	Conserved Protein
JF379_RS02000	COG3759	membrane
JF379_RS02135	COG0523	cobalamin synthesis protein
JF379_RS02160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JF379_RS02170	COG5609	conserved protein (DUF2294)
JF379_RS02185	COG1647	Serine aminopeptidase, S33
JF379_RS02195	COG0733	neurotransmitter:sodium symporter activity
JF379_RS02200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JF379_RS02205	COG0626	cystathionine gamma-synthase activity
JF379_RS02215	COG2011	ABC-type metal ion transport system permease component
JF379_RS02220	COG1464	Belongs to the NlpA lipoprotein family
JF379_RS02255	COG0583	DNA-binding transcription factor activity
JF379_RS02260	COG0069	glutamate synthase activity
JF379_RS02260	COG0070	glutamate synthase
JF379_RS02260	COG0067	glutamate synthase
JF379_RS02265	COG0493	'glutamate synthase
JF379_RS02275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JF379_RS02275	COG1263	PTS System
JF379_RS02280	COG0366	Alpha amylase catalytic
JF379_RS02285	COG2188	Transcriptional regulator
JF379_RS02305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JF379_RS02340	COG1982	Orn Lys Arg decarboxylase major
JF379_RS02350	COG3870	Protein conserved in bacteria
JF379_RS02355	COG0470	DNA polymerase III
JF379_RS02360	COG1774	PSP1 C-terminal conserved region
JF379_RS02370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JF379_RS02380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JF379_RS02390	COG0084	hydrolase, TatD family'
JF379_RS02395	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JF379_RS02405	COG4466	Protein conserved in bacteria
JF379_RS02415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JF379_RS02420	COG0251	oxidation-reduction process
JF379_RS02460	COG2244	polysaccharide biosynthetic process
JF379_RS02465	COG3956	TIGRFAM MazG family protein
JF379_RS02470	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JF379_RS02480	COG1098	S1 RNA binding domain
JF379_RS02495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JF379_RS02520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JF379_RS02615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JF379_RS02630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JF379_RS02640	COG3880	PFAM UvrB UvrC protein
JF379_RS02655	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JF379_RS02660	COG4956	integral membrane protein (PIN domain superfamily)
JF379_RS02680	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JF379_RS02735	COG2813	Specifically methylates the guanine in position
JF379_RS02775	COG1473	amidohydrolase
JF379_RS02805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JF379_RS02810	COG1428	Deoxynucleoside kinase
JF379_RS02815	COG1428	Deoxynucleoside kinase
JF379_RS02825	COG0561	phosphatase activity
JF379_RS02860	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JF379_RS02965	COG0095	Lipoate-protein ligase
JF379_RS02970	COG0083	homoserine kinase activity
JF379_RS02990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JF379_RS03075	COG0667	Aldo Keto reductase
JF379_RS03080	COG0655	NAD(P)H dehydrogenase (quinone) activity
JF379_RS03090	COG1078	dGTPase activity
JF379_RS03125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JF379_RS03130	COG4139	cobalamin transport
JF379_RS03180	COG4974	Belongs to the 'phage' integrase family
JF379_RS03230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JF379_RS03235	COG1121	(ABC) transporter
JF379_RS03240	COG1321	iron dependent repressor
JF379_RS03250	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JF379_RS03260	COG1682	transport, permease protein
JF379_RS03265	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JF379_RS03275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JF379_RS03280	COG1686	Belongs to the peptidase S11 family
JF379_RS03285	COG1132	(ABC) transporter
JF379_RS03290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JF379_RS03300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JF379_RS03305	COG1120	ATPase activity
JF379_RS03310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF379_RS03315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF379_RS03320	COG2376	Dihydroxyacetone kinase
JF379_RS03330	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JF379_RS03340	COG3949	Membrane
JF379_RS03360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JF379_RS03375	COG1136	(ABC) transporter
JF379_RS03380	COG0577	efflux transmembrane transporter activity
JF379_RS03385	COG1392	Phosphate transport regulator
JF379_RS03390	COG0306	phosphate transporter
JF379_RS03395	COG1388	LysM domain
JF379_RS03395	COG3942	CHAP domain
JF379_RS03435	COG0583	DNA-binding transcription factor activity
JF379_RS03440	COG2814	Major facilitator Superfamily
JF379_RS03445	COG2839	Protein conserved in bacteria
JF379_RS03475	COG1611	Belongs to the LOG family
JF379_RS03495	COG4988	ABC transporter
JF379_RS03500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JF379_RS03515	COG4989	oxidoreductase activity
JF379_RS03525	COG0471	metal ion transport
JF379_RS03530	COG0415	Belongs to the DNA photolyase family
JF379_RS03560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JF379_RS03565	COG1349	DNA-binding transcription factor activity
JF379_RS03570	COG1105	Belongs to the carbohydrate kinase PfkB family
JF379_RS03575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JF379_RS03575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JF379_RS03575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JF379_RS03580	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JF379_RS03585	COG1253	flavin adenine dinucleotide binding
JF379_RS03590	COG0656	L-ascorbic acid biosynthetic process
JF379_RS03595	COG0463	Glycosyl transferase, family 2
JF379_RS03630	COG0720	synthase
JF379_RS03640	COG0512	Glutamine amidotransferase of anthranilate synthase
JF379_RS03640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JF379_RS03645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JF379_RS03675	COG0488	(ABC) transporter
JF379_RS03680	COG0514	ATP-dependent DNA helicase (RecQ)
JF379_RS03685	COG0517	IMP dehydrogenase activity
JF379_RS03685	COG1125	glycine betaine transport
JF379_RS03690	COG1174	glycine betaine transport
JF379_RS03715	COG3104	oligopeptide transport
JF379_RS03735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JF379_RS03740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JF379_RS03750	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF379_RS03755	COG4605	iron ion homeostasis
JF379_RS03760	COG4604	ABC transporter, ATP-binding protein
JF379_RS03765	COG4607	ABC-type enterochelin transport system periplasmic component
JF379_RS03820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JF379_RS03825	COG1739	Uncharacterized protein family UPF0029
JF379_RS03835	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JF379_RS03840	COG1040	competence protein
JF379_RS03870	COG3942	CHAP domain
JF379_RS03870	COG1388	LysM domain
JF379_RS03925	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JF379_RS03985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JF379_RS03990	COG1647	Serine aminopeptidase, S33
JF379_RS03995	COG0557	exoribonuclease II activity
JF379_RS04090	COG5484	DNA packaging
JF379_RS04090	COG3728	DNA packaging
JF379_RS04180	COG1278	Cold shock
JF379_RS04220	COG0406	alpha-ribazole phosphatase activity
JF379_RS04225	COG1279	arginine transmembrane transporter activity
JF379_RS04250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JF379_RS04255	COG1393	Belongs to the ArsC family
JF379_RS04265	COG3878	Protein conserved in bacteria
JF379_RS04270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JF379_RS04285	COG2011	ABC-type metal ion transport system permease component
JF379_RS04290	COG1464	Belongs to the NlpA lipoprotein family
JF379_RS04305	COG0396	ATPase activity
JF379_RS04310	COG0719	Fe-S assembly protein
JF379_RS04320	COG0822	iron-sulfur transferase activity
JF379_RS04465	COG0756	dUTP diphosphatase activity
JF379_RS04620	COG1388	LysM domain
JF379_RS04620	COG5632	N-Acetylmuramoyl-L-alanine amidase
JF379_RS04635	COG1253	flavin adenine dinucleotide binding
JF379_RS04645	COG1801	Protein of unknown function DUF72
JF379_RS04650	COG0730	response to heat
JF379_RS04665	COG4470	Protein conserved in bacteria
JF379_RS04675	COG2445	Protein of unknown function DUF86
JF379_RS04705	COG1696	Membrane protein involved in D-alanine export
JF379_RS04715	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JF379_RS04720	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JF379_RS04725	COG4837	Protein of unknown function (DUF1462)
JF379_RS04730	COG1252	NADH dehydrogenase
JF379_RS04740	COG0316	Belongs to the HesB IscA family
JF379_RS04750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JF379_RS04755	COG2056	Na+-H+ antiporter family
JF379_RS04760	COG2050	protein possibly involved in aromatic compounds catabolism
JF379_RS04815	COG1098	S1 RNA binding domain
JF379_RS04820	COG1902	pentaerythritol trinitrate reductase activity
JF379_RS04835	COG0584	glycerophosphoryl diester phosphodiesterase
JF379_RS04855	COG0398	Pfam SNARE associated Golgi protein
JF379_RS04895	COG0561	phosphatase activity
JF379_RS04920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JF379_RS04935	COG1881	PFAM PEBP family protein
JF379_RS04965	COG0601	transmembrane transport
JF379_RS04970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JF379_RS04975	COG0444	Belongs to the ABC transporter superfamily
JF379_RS04980	COG4608	Belongs to the ABC transporter superfamily
JF379_RS04985	COG4166	transmembrane transport
JF379_RS04990	COG0747	negative chemotaxis
JF379_RS04995	COG0444	Belongs to the ABC transporter superfamily
JF379_RS05000	COG4608	Belongs to the ABC transporter superfamily
JF379_RS05005	COG0601	transmembrane transport
JF379_RS05010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JF379_RS05035	COG1164	Oligoendopeptidase f
JF379_RS05045	COG2346	COG2346, Truncated hemoglobins
JF379_RS05060	COG2357	RelA SpoT domain protein
JF379_RS05070	COG0564	pseudouridine synthase activity
JF379_RS05075	COG2239	Acts as a magnesium transporter
JF379_RS05080	COG0569	domain protein
JF379_RS05080	COG0475	glutathione-regulated potassium exporter activity
JF379_RS05090	COG0628	permease
JF379_RS05095	COG1115	amino acid carrier protein
JF379_RS05135	COG0861	Integral membrane protein TerC family
JF379_RS05145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JF379_RS05150	COG0737	Belongs to the 5'-nucleotidase family
JF379_RS05165	COG4903	ComK protein
JF379_RS05180	COG4873	Protein conserved in bacteria
JF379_RS05235	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JF379_RS05245	COG2314	TM2 domain
JF379_RS05250	COG0456	acetyltransferase
JF379_RS05255	COG1575	Belongs to the MenA family. Type 1 subfamily
JF379_RS05260	COG1169	isochorismate synthase
JF379_RS05270	COG2267	carboxylic ester hydrolase activity
JF379_RS05295	COG0436	Aminotransferase
JF379_RS05300	COG3594	Acyltransferase
JF379_RS05330	COG1316	TRANSCRIPTIONal
JF379_RS05375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JF379_RS05390	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JF379_RS05420	COG0138	bifunctional purine biosynthesis protein purh
JF379_RS05430	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JF379_RS05435	COG4172	Belongs to the ABC transporter superfamily
JF379_RS05440	COG4721	ABC-type cobalt transport system, permease component
JF379_RS05455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JF379_RS05475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JF379_RS05480	COG1271	oxidase subunit
JF379_RS05485	COG1294	oxidase, subunit
JF379_RS05490	COG0569	domain protein
JF379_RS05555	COG1176	ABC-type spermidine putrescine transport system, permease component I
JF379_RS05560	COG1177	transmembrane transport
JF379_RS05565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JF379_RS05590	COG0483	inositol monophosphate 1-phosphatase activity
JF379_RS05600	COG1217	gtp-binding protein TYPA
JF379_RS05610	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JF379_RS05620	COG0772	Belongs to the SEDS family
JF379_RS05650	COG3679	Belongs to the UPF0342 family
JF379_RS05670	COG0742	ribosomal rna small subunit methyltransferase
JF379_RS05725	COG4509	Sortase family
JF379_RS05740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JF379_RS05770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JF379_RS05770	COG1796	DNA polymerase
JF379_RS05795	COG2009	succinate dehydrogenase
JF379_RS05800	COG1053	succinate dehydrogenase
JF379_RS05805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JF379_RS05910	COG1288	antiporter activity
JF379_RS05945	COG1011	Hydrolase
JF379_RS05970	COG4839	cell division protein FtsL
JF379_RS05975	COG0768	penicillin binding
JF379_RS05990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JF379_RS06010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JF379_RS06020	COG0762	integral membrane protein
JF379_RS06025	COG2302	S4 RNA-binding domain
JF379_RS06030	COG3599	regulation of cell shape
JF379_RS06040	COG2514	catechol 2,3-dioxygenase activity
JF379_RS06055	COG0564	pseudouridine synthase activity
JF379_RS06065	COG2233	PERMEase
JF379_RS06110	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JF379_RS06125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JF379_RS06130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JF379_RS06140	COG2314	TM2 domain
JF379_RS06155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JF379_RS06155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JF379_RS06165	COG0631	protein serine/threonine phosphatase activity
JF379_RS06180	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JF379_RS06195	COG1302	Protein conserved in bacteria
JF379_RS06240	COG1196	nuclear chromosome segregation
JF379_RS06245	COG0552	protein localization to endoplasmic reticulum
JF379_RS06255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JF379_RS06315	COG0758	DNA mediated transformation
JF379_RS06410	COG0195	Participates in both transcription termination and antitermination
JF379_RS06415	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JF379_RS06440	COG0196	riboflavin kinase activity
JF379_RS06465	COG2188	Transcriptional regulator
JF379_RS06475	COG0612	Peptidase, M16
JF379_RS06480	COG0300	oxidoreductase activity
JF379_RS06500	COG1058	Belongs to the CinA family
JF379_RS06500	COG1546	Belongs to the CinA family
JF379_RS06520	COG1692	metallophosphoesterase
JF379_RS06525	COG0674	pyruvate-flavodoxin oxidoreductase activity
JF379_RS06525	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JF379_RS06530	COG1013	pyruvate-flavodoxin oxidoreductase activity
JF379_RS06565	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JF379_RS06570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JF379_RS06595	COG1923	regulation of RNA biosynthetic process
JF379_RS06605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JF379_RS06610	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JF379_RS06615	COG0789	Transcriptional regulator
JF379_RS06705	COG1131	(ABC) transporter
JF379_RS06720	COG2197	response regulator
JF379_RS06730	COG1525	nuclease
JF379_RS06745	COG0527	aspartate kinase activity
JF379_RS06750	COG0460	homoserine dehydrogenase
JF379_RS06755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JF379_RS06780	COG0833	amino acid
JF379_RS06805	COG2340	Cysteine-rich secretory protein family
JF379_RS06840	COG4846	Membrane protein involved in cytochrome C biogenesis
JF379_RS06860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JF379_RS06870	COG0824	Thioesterase
JF379_RS06890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JF379_RS06895	COG1115	amino acid carrier protein
JF379_RS06910	COG0628	permease
JF379_RS06935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JF379_RS06945	COG1363	Peptidase, m42
JF379_RS06950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JF379_RS06955	COG0512	Glutamine amidotransferase of anthranilate synthase
JF379_RS07045	COG0704	Plays a role in the regulation of phosphate uptake
JF379_RS07055	COG0581	inorganic phosphate transmembrane transporter activity
JF379_RS07060	COG0573	inorganic phosphate transmembrane transporter activity
JF379_RS07080	COG0488	(ABC) transporter
JF379_RS07085	COG0527	aspartate kinase activity
JF379_RS07090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JF379_RS07165	COG4548	von Willebrand factor, type A
JF379_RS07170	COG0714	Associated with various cellular activities
JF379_RS07215	COG0671	phosphoesterase, PA-phosphatase related
JF379_RS07295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JF379_RS07315	COG0531	amino acid
JF379_RS07330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JF379_RS07335	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JF379_RS07350	COG0116	Belongs to the methyltransferase superfamily
JF379_RS07385	COG4499	WXG100 protein secretion system (Wss), protein YukC
JF379_RS07385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JF379_RS07395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JF379_RS07400	COG3935	DnaD domain protein
JF379_RS07425	COG0438	transferase activity, transferring glycosyl groups
JF379_RS07430	COG1694	Mazg nucleotide pyrophosphohydrolase
JF379_RS07435	COG2738	Putative neutral zinc metallopeptidase
JF379_RS07440	COG4347	Protein of unknown function (DUF1405)
JF379_RS07480	COG0142	geranyltranstransferase activity
JF379_RS07525	COG0492	ferredoxin-NADP+ reductase activity
JF379_RS07540	COG0514	ATP-dependent DNA helicase (RecQ)
JF379_RS07550	COG1141	Ferredoxin
JF379_RS07585	COG5002	protein histidine kinase activity
JF379_RS07590	COG0745	RESPONSE REGULATOR receiver
JF379_RS07595	COG1187	pseudouridine synthase activity
JF379_RS07620	COG0735	belongs to the Fur family
JF379_RS07625	COG0494	nUDIX hydrolase
JF379_RS07630	COG0667	Aldo Keto reductase
JF379_RS07640	COG4221	oxidoreductase activity
JF379_RS07655	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JF379_RS07665	COG0366	Alpha amylase catalytic
JF379_RS07670	COG1609	Transcriptional regulator
JF379_RS07690	COG2195	Cleaves the N-terminal amino acid of tripeptides
JF379_RS07700	COG4129	membrane
JF379_RS07710	COG0508	dehydrogenase complex catalyzes the overall conversion of
JF379_RS07715	COG0022	dehydrogenase e1 component
JF379_RS07720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JF379_RS07725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JF379_RS07730	COG0497	DNA recombination
JF379_RS07760	COG1302	Protein conserved in bacteria
JF379_RS07765	COG0439	Biotin carboxylase
JF379_RS07770	COG0511	ligase activity, forming carbon-carbon bonds
JF379_RS07780	COG0006	proline dipeptidase activity
JF379_RS07795	COG0095	Lipoate-protein ligase
JF379_RS07800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JF379_RS07840	COG4537	Required for transformation and DNA binding
JF379_RS07845	COG1459	type II secretion system
JF379_RS07850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JF379_RS07855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JF379_RS07860	COG0011	TIGRFAM Protein of
JF379_RS07865	COG1940	carbohydrate kinase activity
JF379_RS07870	COG4483	Protein conserved in bacteria
JF379_RS07880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JF379_RS07890	COG0768	penicillin binding
JF379_RS07905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JF379_RS07910	COG1121	(ABC) transporter
JF379_RS07920	COG0513	Belongs to the DEAD box helicase family
JF379_RS07930	COG2384	SAM-dependent methyltransferase
JF379_RS07950	COG0517	IMP dehydrogenase activity
JF379_RS07970	COG0295	cytidine deaminase activity
JF379_RS07985	COG1702	phosphate starvation-inducible protein PhoH
JF379_RS08000	COG1030	water channel activity
JF379_RS08010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JF379_RS08015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JF379_RS08045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JF379_RS08060	COG1466	dna polymerase III delta subunit
JF379_RS08065	COG0658	competence protein
JF379_RS08065	COG2333	competence protein COMEC
JF379_RS08070	COG2131	deaminase
JF379_RS08075	COG2183	response to ionizing radiation
JF379_RS08080	COG2226	methyltransferase
JF379_RS08085	COG0799	negative regulation of ribosome biogenesis
JF379_RS08090	COG1713	HD superfamily hydrolase involved in NAD metabolism
JF379_RS08100	COG1534	Rna-binding protein
JF379_RS08110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JF379_RS08115	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JF379_RS08135	COG3177	Filamentation induced by cAMP protein fic
JF379_RS08140	COG1914	H( )-stimulated, divalent metal cation uptake system
JF379_RS08150	COG0439	Biotin carboxylase
JF379_RS08155	COG0511	ligase activity, forming carbon-carbon bonds
JF379_RS08160	COG1984	allophanate hydrolase subunit 2
JF379_RS08165	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JF379_RS08180	COG0826	peptidase U32
JF379_RS08185	COG0826	peptidase U32
JF379_RS08215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JF379_RS08230	COG1104	cysteine desulfurase activity
JF379_RS08235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JF379_RS08245	COG3237	CsbD-like
JF379_RS08250	COG1959	2 iron, 2 sulfur cluster binding
JF379_RS08255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JF379_RS08260	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JF379_RS08305	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JF379_RS08305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JF379_RS08310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JF379_RS08310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JF379_RS08315	COG1862	Preprotein translocase
JF379_RS08355	COG2868	ribosomal protein
JF379_RS08400	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JF379_RS08405	COG0285	dihydrofolate synthase activity
JF379_RS08415	COG2818	Glycosylase
JF379_RS08450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JF379_RS08485	COG4112	unkown
JF379_RS08505	COG0833	amino acid
JF379_RS08520	COG1484	DNA-dependent DNA replication
JF379_RS08550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JF379_RS08550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JF379_RS08560	COG5002	protein histidine kinase activity
JF379_RS08565	COG0745	RESPONSE REGULATOR receiver
JF379_RS08575	COG0372	Belongs to the citrate synthase family
JF379_RS08580	COG1113	amino acid transport
JF379_RS08605	COG0281	malic enzyme
JF379_RS08615	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JF379_RS08620	COG4109	DRTGG domain
JF379_RS08660	COG0827	DNA restriction-modification system
JF379_RS08670	COG0730	response to heat
JF379_RS08680	COG1104	cysteine desulfurase activity
JF379_RS08695	COG1956	GAF domain-containing protein
JF379_RS08705	COG0584	glycerophosphoryl diester phosphodiesterase
JF379_RS08710	COG1764	response to oxidative stress
JF379_RS08715	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JF379_RS08720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JF379_RS08735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JF379_RS08735	COG1263	PTS System
JF379_RS08740	COG0204	Acyl-transferase
JF379_RS08745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JF379_RS08780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JF379_RS08785	COG0454	-acetyltransferase
JF379_RS08805	COG1605	Chorismate mutase
JF379_RS08805	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JF379_RS08830	COG1674	ftsk spoiiie
JF379_RS08835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JF379_RS08845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JF379_RS08850	COG1363	Peptidase, m42
JF379_RS08860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JF379_RS08870	COG0510	thiamine kinase activity
JF379_RS08890	COG1187	pseudouridine synthase activity
JF379_RS08895	COG2244	polysaccharide biosynthetic process
JF379_RS08900	COG2081	HI0933 family
JF379_RS08920	COG2814	Major facilitator Superfamily
JF379_RS08925	COG1242	4 iron, 4 sulfur cluster binding
JF379_RS08930	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JF379_RS08940	COG2267	carboxylic ester hydrolase activity
JF379_RS08970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JF379_RS08970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JF379_RS08990	COG5632	N-Acetylmuramoyl-L-alanine amidase
JF379_RS08990	COG3266	domain, Protein
JF379_RS08990	COG4193	domain, Protein
JF379_RS09020	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JF379_RS09040	COG0656	L-ascorbic acid biosynthetic process
JF379_RS09060	COG1506	peptidase
JF379_RS09065	COG2816	NAD+ diphosphatase activity
JF379_RS09225	COG1131	(ABC) transporter
JF379_RS09310	COG1388	LysM domain
JF379_RS09310	COG0860	N-Acetylmuramoyl-L-alanine amidase
JF379_RS09360	COG5412	phage tail tape measure protein
JF379_RS09360	COG3953	SLT domain
JF379_RS09525	COG1484	DNA-dependent DNA replication
JF379_RS09545	COG0629	single-stranded DNA binding
JF379_RS09615	COG0582	viral genome integration into host DNA
JF379_RS09665	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JF379_RS09695	COG1131	(ABC) transporter
JF379_RS09700	COG0537	adenosine 5'-monophosphoramidase activity
JF379_RS09730	COG0420	3'-5' exonuclease activity
JF379_RS09755	COG2197	response regulator
JF379_RS09760	COG4585	Histidine kinase
JF379_RS09760	COG2203	Gaf domain
JF379_RS09765	COG0564	pseudouridine synthase activity
JF379_RS09795	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JF379_RS09800	COG1126	abc transporter atp-binding protein
JF379_RS09805	COG0765	amino acid transport
JF379_RS09975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JF379_RS09980	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JF379_RS09990	COG4129	membrane
JF379_RS10015	COG1988	membrane-bound metal-dependent
JF379_RS10025	COG1134	teichoic acid transport
JF379_RS10025	COG1388	LysM domain
JF379_RS10055	COG0535	radical SAM domain protein
JF379_RS10060	COG1607	acyl-coa hydrolase
JF379_RS10065	COG2309	aminopeptidase activity
JF379_RS10085	COG1295	ribonuclease BN
JF379_RS10200	COG4851	CamS sex pheromone cAM373 precursor
JF379_RS10210	COG0210	DNA helicase
JF379_RS10220	COG4496	protein, YerC YecD
JF379_RS10255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JF379_RS10265	COG0077	Prephenate dehydratase
JF379_RS10285	COG1335	isochorismatase
JF379_RS10300	COG1012	belongs to the aldehyde dehydrogenase family
JF379_RS10355	COG1131	(ABC) transporter
JF379_RS10370	COG1725	Transcriptional regulator
JF379_RS10420	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JF379_RS10425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JF379_RS10430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JF379_RS10445	COG5484	DNA packaging
JF379_RS10445	COG3728	DNA packaging
JF379_RS10520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JF379_RS10525	COG1621	beta-fructofuranosidase activity
JF379_RS10530	COG1609	Transcriptional regulator
JF379_RS10535	COG0004	ammonium transporteR
JF379_RS10540	COG0425	Belongs to the sulfur carrier protein TusA family
JF379_RS10545	COG2391	methyltransferase activity
JF379_RS10555	COG0488	(ABC) transporter
JF379_RS10565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JF379_RS10575	COG0456	acetyltransferase
JF379_RS10580	COG1214	PFAM Peptidase M22, glycoprotease
JF379_RS10585	COG0802	atpase or kinase
JF379_RS10600	COG0028	Belongs to the TPP enzyme family
JF379_RS10670	COG2183	response to ionizing radiation
JF379_RS10675	COG1191	sigma factor activity
JF379_RS10685	COG1366	Belongs to the anti-sigma-factor antagonist family
JF379_RS10690	COG2208	phosphoserine phosphatase activity
JF379_RS10720	COG3428	Bacterial PH domain
JF379_RS10750	COG2205	protein histidine kinase activity
JF379_RS10755	COG0745	RESPONSE REGULATOR receiver
JF379_RS10765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JF379_RS10775	COG0772	Belongs to the SEDS family
JF379_RS10790	COG1937	Protein conserved in bacteria
JF379_RS10800	COG1418	mRNA catabolic process
JF379_RS10835	COG0629	single-stranded DNA binding
JF379_RS10910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JF379_RS10935	COG0009	L-threonylcarbamoyladenylate synthase
JF379_RS10940	COG2890	protein-(glutamine-N5) methyltransferase activity
JF379_RS10960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JF379_RS11000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JF379_RS11045	COG0813	purine-nucleoside phosphorylase activity
JF379_RS11050	COG0783	Belongs to the Dps family
JF379_RS11070	COG1482	cell wall glycoprotein biosynthetic process
JF379_RS11075	COG0702	epimerase
JF379_RS11080	COG0640	Transcriptional regulator
JF379_RS11105	COG0561	phosphatase activity
JF379_RS11110	COG1119	ATPase activity
JF379_RS11125	COG3711	transcriptional antiterminator
JF379_RS11155	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JF379_RS11215	COG0489	protein tyrosine kinase activity
JF379_RS11220	COG2814	Major facilitator Superfamily
JF379_RS11235	COG1272	protein, Hemolysin III
JF379_RS11245	COG1988	membrane-bound metal-dependent
JF379_RS11255	COG3314	Sporulation integral membrane protein YlbJ
JF379_RS11260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF379_RS11265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JF379_RS11270	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JF379_RS11280	COG3457	Alanine racemase
JF379_RS11285	COG4264	IucA IucC family
JF379_RS11290	COG2814	Major facilitator Superfamily
JF379_RS11315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JF379_RS11325	COG2130	NADP-dependent
JF379_RS11395	COG0656	L-ascorbic acid biosynthetic process
JF379_RS11400	COG0789	Transcriptional regulator
JF379_RS11410	COG5492	domain, Protein
JF379_RS11420	COG3527	Alpha-acetolactate decarboxylase
JF379_RS11425	COG0028	Belongs to the TPP enzyme family
JF379_RS11500	COG0201	protein transport
JF379_RS11615	COG2252	PERMEase
JF379_RS11660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JF379_RS11720	COG1763	Mo-molybdopterin cofactor biosynthetic process
JF379_RS11740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JF379_RS11745	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JF379_RS11750	COG4149	molybdate abc transporter
JF379_RS11755	COG0725	ABC transporter, periplasmic molybdate-binding protein
JF379_RS11770	COG1268	BioY protein
JF379_RS11785	COG1960	acyl-CoA dehydrogenase activity
JF379_RS11790	COG4413	Urea transporter
JF379_RS11860	COG1757	Na H antiporter
JF379_RS11875	COG3942	CHAP domain
JF379_RS11945	COG1113	amino acid transport
JF379_RS11965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JF379_RS11970	COG0385	Bile acid
JF379_RS11980	COG1263	PTS System
JF379_RS11980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JF379_RS11985	COG1737	Transcriptional regulator
JF379_RS12005	COG1028	Short-chain dehydrogenase reductase Sdr
JF379_RS12010	COG1473	amidohydrolase
JF379_RS12025	COG0583	DNA-binding transcription factor activity
JF379_RS12045	COG2258	MOSC domain
JF379_RS12070	COG4152	abc transporter atp-binding protein
JF379_RS12075	COG3152	Membrane
JF379_RS12085	COG0786	glutamate:sodium symporter activity
JF379_RS12095	COG0598	Magnesium transport protein CorA
JF379_RS12110	COG0657	acetylesterase activity
JF379_RS12120	COG2814	Major facilitator Superfamily
JF379_RS12125	COG1566	PFAM secretion protein HlyD family protein
JF379_RS12135	COG2814	Major facilitator Superfamily
JF379_RS12195	COG1620	l-lactate permease
JF379_RS12215	COG0604	alcohol dehydrogenase
JF379_RS12245	COG1511	domain protein
JF379_RS12260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JF379_RS12260	COG1263	PTS System
JF379_RS12275	COG3871	stress protein (general stress protein 26)
JF379_RS12315	COG0789	Transcriptional regulator
JF379_RS12335	COG2181	nitrate reductase activity
JF379_RS12345	COG1140	nitrate reductase beta subunit
JF379_RS12350	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JF379_RS12360	COG2146	nitrite reductase [NAD(P)H] activity
JF379_RS12365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JF379_RS12375	COG0454	-acetyltransferase
JF379_RS12380	COG2116	formate transmembrane transporter activity
JF379_RS12395	COG3443	Belongs to the bacterial solute-binding protein 9 family
JF379_RS12395	COG0803	Belongs to the bacterial solute-binding protein 9 family
JF379_RS12430	COG1126	abc transporter atp-binding protein
JF379_RS12435	COG0765	amino acid transport
JF379_RS12440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JF379_RS12445	COG2814	Major facilitator Superfamily
JF379_RS12460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JF379_RS12500	COG0156	8-amino-7-oxononanoate synthase activity
JF379_RS12510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JF379_RS12515	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JF379_RS12525	COG1132	(ABC) transporter
JF379_RS12530	COG1132	(ABC) transporter
JF379_RS12530	COG2375	cellular response to nickel ion
JF379_RS12545	COG1929	Belongs to the glycerate kinase type-1 family
JF379_RS12555	COG2814	Major facilitator Superfamily
JF379_RS12575	COG1113	amino acid transport
JF379_RS12585	COG0531	amino acid
JF379_RS12600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JF379_RS12610	COG1174	glycine betaine transport
JF379_RS12620	COG1174	glycine betaine transport
JF379_RS12640	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JF379_RS12645	COG0531	amino acid
JF379_RS12650	COG2272	Belongs to the type-B carboxylesterase lipase family
JF379_RS12655	COG2814	Major facilitator Superfamily
JF379_RS12660	COG0390	transport system, permease component
JF379_RS12665	COG4619	ABC transporter
JF379_RS12670	COG1363	Peptidase, m42
JF379_RS12685	COG4808	Protein conserved in bacteria
JF379_RS12690	COG0069	glutamate synthase activity
JF379_RS12705	COG1124	(ABC) transporter
JF379_RS12710	COG0444	Belongs to the ABC transporter superfamily
JF379_RS12715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JF379_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
JF379_RS12755	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JF379_RS12760	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JF379_RS12830	COG0494	nUDIX hydrolase
JF379_RS12900	COG1070	Carbohydrate kinase
JF379_RS12905	COG1802	Transcriptional regulator
JF379_RS12910	COG0789	Transcriptional regulator
JF379_RS12915	COG2357	RelA SpoT domain protein
JF379_RS12920	COG4876	unkown
JF379_RS12930	COG2271	Major facilitator Superfamily
JF379_RS12935	COG0586	Pfam SNARE associated Golgi protein
JF379_RS12940	COG1131	(ABC) transporter
JF379_RS12955	COG3949	Membrane
JF379_RS12960	COG0400	carboxylic ester hydrolase activity
JF379_RS12965	COG0346	lactoylglutathione lyase activity
JF379_RS12970	COG1846	Transcriptional regulator
JF379_RS12980	COG2514	catechol 2,3-dioxygenase activity
JF379_RS12995	COG0561	phosphatase activity
JF379_RS13000	COG1131	(ABC) transporter
JF379_RS13010	COG3764	Sortase (surface protein transpeptidase)
JF379_RS13030	COG1760	l-serine dehydratase
JF379_RS13035	COG1760	l-serine dehydratase
JF379_RS13050	COG0697	spore germination
JF379_RS13055	COG0657	acetylesterase activity
JF379_RS13075	COG0028	Belongs to the TPP enzyme family
JF379_RS13090	COG0583	DNA-binding transcription factor activity
JF379_RS13100	COG3942	CHAP domain
JF379_RS13110	COG3425	synthase
JF379_RS13115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JF379_RS13140	COG2409	Drug exporters of the RND superfamily
JF379_RS13185	COG0436	Aminotransferase
JF379_RS13215	COG3942	CHAP domain
JF379_RS13220	COG2755	lipolytic protein G-D-S-L family
JF379_RS13220	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JF379_RS13325	COG3001	Fructosamine kinase
JF379_RS13330	COG0167	dihydroorotate dehydrogenase activity
JF379_RS13380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JF379_RS13385	COG3527	Alpha-acetolactate decarboxylase
JF379_RS13395	COG0531	amino acid
JF379_RS13425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JF379_RS13445	COG1012	belongs to the aldehyde dehydrogenase family
JF379_RS13455	COG1510	regulation of RNA biosynthetic process
JF379_RS13465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JF379_RS13490	COG2851	Citrate transporter
JF379_RS13500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JF379_RS13510	COG0386	Belongs to the glutathione peroxidase family
JF379_RS13530	COG1136	(ABC) transporter
JF379_RS13535	COG2205	protein histidine kinase activity
JF379_RS13540	COG0745	RESPONSE REGULATOR receiver
JF379_RS13550	COG1785	Belongs to the alkaline phosphatase family
JF379_RS13560	COG1846	Transcriptional regulator
JF379_RS13605	COG1438	arginine binding
JF379_RS13625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JF379_RS13625	COG3711	transcriptional antiterminator
JF379_RS13630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JF379_RS13630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JF379_RS13630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JF379_RS13635	COG1482	cell wall glycoprotein biosynthetic process
JF379_RS13645	COG3942	CHAP domain
JF379_RS13645	COG1705	Flagellar rod assembly protein muramidase FlgJ
JF379_RS13650	COG1535	isochorismatase
JF379_RS13650	COG3433	isochorismatase activity
JF379_RS13665	COG0438	transferase activity, transferring glycosyl groups
JF379_RS13680	COG1073	alpha beta
JF379_RS13700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JF379_RS13720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JF379_RS13775	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JF379_RS13810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JF379_RS13890	COG0471	metal ion transport
JF379_RS13895	COG2962	Rard protein
JF379_RS13905	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JF379_RS13920	COG1136	(ABC) transporter
JF379_RS13925	COG0577	efflux transmembrane transporter activity
JF379_RS13935	COG1278	Cold shock
JF379_RS13955	COG1475	DNA binding
JF379_RS14045	COG0386	Belongs to the glutathione peroxidase family
JF379_RS14055	COG2814	Major facilitator Superfamily
JF379_RS14080	COG4607	ABC-type enterochelin transport system periplasmic component