locus-tag	class	description
MS7_RS00105	COG0305	Participates in initiation and elongation during chromosome replication
MS7_RS00125	COG2501	S4 domain
MS7_RS00140	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MS7_RS00145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MS7_RS00170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MS7_RS00180	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MS7_RS00190	COG0305	Participates in initiation and elongation during chromosome replication
MS7_RS00220	COG4863	YycH protein
MS7_RS00230	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MS7_RS00235	COG0737	Belongs to the 5'-nucleotidase family
MS7_RS00270	COG0584	glycerophosphoryl diester phosphodiesterase
MS7_RS00275	COG2030	dehydratase
MS7_RS00330	COG3682	Transcriptional regulator
MS7_RS00345	COG3173	Aminoglycoside phosphotransferase
MS7_RS00360	COG1279	arginine transmembrane transporter activity
MS7_RS00370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS7_RS00390	COG2205	protein histidine kinase activity
MS7_RS00405	COG1968	undecaprenyl-diphosphatase activity
MS7_RS00420	COG0456	acetyltransferase
MS7_RS00430	COG2378	regulation of single-species biofilm formation
MS7_RS00550	COG0823	Involved in the tonB-independent uptake of proteins
MS7_RS00590	COG1473	amidohydrolase
MS7_RS00600	COG1283	sodium-dependent phosphate transmembrane transporter activity
MS7_RS00605	COG4716	Myosin-crossreactive antigen
MS7_RS00615	COG1620	l-lactate permease
MS7_RS00630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7_RS00635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7_RS00640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MS7_RS00650	COG2423	ornithine cyclodeaminase activity
MS7_RS00655	COG4264	IucA IucC family
MS7_RS00660	COG2814	Major facilitator Superfamily
MS7_RS00665	COG4264	IucA IucC family
MS7_RS00670	COG4264	IucA IucC family
MS7_RS00680	COG0019	diaminopimelate decarboxylase activity
MS7_RS00685	COG1475	DNA binding
MS7_RS00710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MS7_RS00715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MS7_RS00720	COG0438	transferase activity, transferring glycosyl groups
MS7_RS00755	COG0813	purine-nucleoside phosphorylase activity
MS7_RS00760	COG2814	Major facilitator Superfamily
MS7_RS00780	COG3639	organic phosphonate transmembrane transporter activity
MS7_RS00800	COG0737	Belongs to the 5'-nucleotidase family
MS7_RS00830	COG1012	belongs to the aldehyde dehydrogenase family
MS7_RS00830	COG1454	alcohol dehydrogenase
MS7_RS00855	COG1086	Polysaccharide biosynthesis protein
MS7_RS00865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MS7_RS00895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MS7_RS00905	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MS7_RS00910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MS7_RS00920	COG2832	Protein of unknown function (DUF454)
MS7_RS00960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MS7_RS00965	COG1960	acyl-CoA dehydrogenase activity
MS7_RS00970	COG5609	conserved protein (DUF2294)
MS7_RS01020	COG1114	Component of the transport system for branched-chain amino acids
MS7_RS01025	COG1335	isochorismatase
MS7_RS01030	COG3961	Belongs to the TPP enzyme family
MS7_RS01060	COG1737	Transcriptional regulator
MS7_RS01095	COG0601	transmembrane transport
MS7_RS01100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS7_RS01110	COG0405	Gamma-glutamyltransferase
MS7_RS01130	COG3842	ATPase activity
MS7_RS01140	COG1175	transmembrane transport
MS7_RS01145	COG3833	ABC-type maltose transport systems, permease component
MS7_RS01150	COG0673	inositol 2-dehydrogenase activity
MS7_RS01155	COG0673	inositol 2-dehydrogenase activity
MS7_RS01165	COG1755	Isoprenylcysteine carboxyl methyltransferase
MS7_RS01230	COG0183	Belongs to the thiolase family
MS7_RS01240	COG1960	acyl-CoA dehydrogenase activity
MS7_RS01245	COG0318	PFAM AMP-dependent synthetase and ligase
MS7_RS01260	COG0747	negative chemotaxis
MS7_RS01265	COG3189	MarR family transcriptional regulator
MS7_RS01295	COG1263	PTS System
MS7_RS01295	COG2190	(PTS) system
MS7_RS01295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7_RS01300	COG1957	nucleoside hydrolase
MS7_RS01325	COG3414	Phosphotransferase system galactitol-specific IIB component
MS7_RS01330	COG3775	system Galactitol-specific IIC component
MS7_RS01335	COG1063	alcohol dehydrogenase
MS7_RS01345	COG1063	alcohol dehydrogenase
MS7_RS01355	COG1063	alcohol dehydrogenase
MS7_RS01360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MS7_RS01365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MS7_RS01375	COG1063	alcohol dehydrogenase
MS7_RS01380	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MS7_RS01415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS7_RS01420	COG1263	PTS System
MS7_RS01420	COG2190	(PTS) system
MS7_RS01420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7_RS01425	COG2723	6-phospho-beta-galactosidase activity
MS7_RS01430	COG2226	methyltransferase
MS7_RS01490	COG1131	(ABC) transporter
MS7_RS01510	COG3942	CHAP domain
MS7_RS01510	COG1388	LysM domain
MS7_RS01630	COG1114	Component of the transport system for branched-chain amino acids
MS7_RS01640	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MS7_RS01650	COG0577	efflux transmembrane transporter activity
MS7_RS01675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MS7_RS01680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MS7_RS01705	COG3314	Sporulation integral membrane protein YlbJ
MS7_RS01730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS7_RS01760	COG3037	sugar-specific permease SgaT UlaA
MS7_RS01770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7_RS01775	COG3711	transcriptional antiterminator
MS7_RS01795	COG2271	Major facilitator Superfamily
MS7_RS01800	COG0346	lactoylglutathione lyase activity
MS7_RS01805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS7_RS01810	COG0431	NADPH-dependent FMN reductase
MS7_RS01825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS7_RS01830	COG2822	iron ion transport
MS7_RS01840	COG0672	)-iron permease
MS7_RS01845	COG0805	protein transport
MS7_RS01850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MS7_RS01860	COG1476	TRANSCRIPTIONal
MS7_RS01870	COG1131	(ABC) transporter
MS7_RS01905	COG0646	methionine synthase
MS7_RS01905	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MS7_RS01910	COG0626	cystathionine gamma-synthase activity
MS7_RS01915	COG0626	cystathionine gamma-synthase activity
MS7_RS01920	COG1475	DNA binding
MS7_RS01925	COG0668	transmembrane transport
MS7_RS01930	COG4481	Protein conserved in bacteria
MS7_RS01935	COG0012	GTP binding
MS7_RS02020	COG3634	alkyl hydroperoxide reductase activity
MS7_RS02035	COG1823	symporter activity
MS7_RS02065	COG2233	PERMEase
MS7_RS02140	COG1683	Conserved Protein
MS7_RS02150	COG3759	membrane
MS7_RS02310	COG0523	cobalamin synthesis protein
MS7_RS02320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MS7_RS02330	COG5609	conserved protein (DUF2294)
MS7_RS02345	COG1647	Serine aminopeptidase, S33
MS7_RS02355	COG0733	neurotransmitter:sodium symporter activity
MS7_RS02360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MS7_RS02365	COG0626	cystathionine gamma-synthase activity
MS7_RS02375	COG2011	ABC-type metal ion transport system permease component
MS7_RS02380	COG1464	Belongs to the NlpA lipoprotein family
MS7_RS02415	COG0583	DNA-binding transcription factor activity
MS7_RS02420	COG0070	glutamate synthase
MS7_RS02420	COG0069	glutamate synthase activity
MS7_RS02420	COG0067	glutamate synthase
MS7_RS02425	COG0493	'glutamate synthase
MS7_RS02435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7_RS02435	COG1263	PTS System
MS7_RS02440	COG0366	Alpha amylase catalytic
MS7_RS02445	COG2188	Transcriptional regulator
MS7_RS02460	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MS7_RS02495	COG1982	Orn Lys Arg decarboxylase major
MS7_RS02505	COG3870	Protein conserved in bacteria
MS7_RS02515	COG0470	DNA polymerase III
MS7_RS02520	COG1774	PSP1 C-terminal conserved region
MS7_RS02530	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MS7_RS02540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MS7_RS02555	COG0084	hydrolase, TatD family'
MS7_RS02560	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MS7_RS02570	COG4466	Protein conserved in bacteria
MS7_RS02580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MS7_RS02585	COG0251	oxidation-reduction process
MS7_RS02630	COG2244	polysaccharide biosynthetic process
MS7_RS02635	COG3956	TIGRFAM MazG family protein
MS7_RS02640	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MS7_RS02650	COG1098	S1 RNA binding domain
MS7_RS02665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MS7_RS02690	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MS7_RS02765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS7_RS02780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MS7_RS02790	COG3880	PFAM UvrB UvrC protein
MS7_RS02810	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MS7_RS02815	COG4956	integral membrane protein (PIN domain superfamily)
MS7_RS02835	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MS7_RS02885	COG2813	Specifically methylates the guanine in position
MS7_RS02925	COG1473	amidohydrolase
MS7_RS02955	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MS7_RS02960	COG1428	Deoxynucleoside kinase
MS7_RS02965	COG1428	Deoxynucleoside kinase
MS7_RS02975	COG0561	phosphatase activity
MS7_RS03015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MS7_RS03120	COG0095	Lipoate-protein ligase
MS7_RS03125	COG0083	homoserine kinase activity
MS7_RS03145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS7_RS03325	COG1783	phage Terminase large subunit
MS7_RS03455	COG5632	N-Acetylmuramoyl-L-alanine amidase
MS7_RS03455	COG1388	LysM domain
MS7_RS03470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS7_RS03515	COG0667	Aldo Keto reductase
MS7_RS03520	COG0655	NAD(P)H dehydrogenase (quinone) activity
MS7_RS03530	COG1078	dGTPase activity
MS7_RS03565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MS7_RS03570	COG4139	cobalamin transport
MS7_RS03620	COG4974	Belongs to the 'phage' integrase family
MS7_RS03665	COG0803	Belongs to the bacterial solute-binding protein 9 family
MS7_RS03670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MS7_RS03675	COG1121	(ABC) transporter
MS7_RS03680	COG1321	iron dependent repressor
MS7_RS03690	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MS7_RS03700	COG1682	transport, permease protein
MS7_RS03705	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MS7_RS03710	COG1216	Glycosyl transferase, family 2
MS7_RS03715	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MS7_RS03720	COG1686	Belongs to the peptidase S11 family
MS7_RS03725	COG1132	(ABC) transporter
MS7_RS03730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MS7_RS03740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MS7_RS03745	COG1120	ATPase activity
MS7_RS03750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7_RS03755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7_RS03760	COG2376	Dihydroxyacetone kinase
MS7_RS03770	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
MS7_RS03780	COG3949	Membrane
MS7_RS03805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MS7_RS03820	COG1136	(ABC) transporter
MS7_RS03825	COG0577	efflux transmembrane transporter activity
MS7_RS03830	COG1392	Phosphate transport regulator
MS7_RS03835	COG0306	phosphate transporter
MS7_RS03840	COG3942	CHAP domain
MS7_RS03840	COG1388	LysM domain
MS7_RS03850	COG4977	sequence-specific DNA binding
MS7_RS03850	COG1917	Cupin 2, conserved barrel domain protein
MS7_RS03880	COG0583	DNA-binding transcription factor activity
MS7_RS03890	COG2814	Major facilitator Superfamily
MS7_RS03895	COG2839	Protein conserved in bacteria
MS7_RS03925	COG1611	Belongs to the LOG family
MS7_RS03945	COG4988	ABC transporter
MS7_RS03950	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MS7_RS03960	COG0523	cobalamin synthesis protein
MS7_RS03965	COG4989	oxidoreductase activity
MS7_RS03975	COG0471	metal ion transport
MS7_RS03980	COG0415	Belongs to the DNA photolyase family
MS7_RS04010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MS7_RS04015	COG1349	DNA-binding transcription factor activity
MS7_RS04020	COG1105	Belongs to the carbohydrate kinase PfkB family
MS7_RS04025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7_RS04025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7_RS04025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7_RS04035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MS7_RS04040	COG1253	flavin adenine dinucleotide binding
MS7_RS04045	COG0656	L-ascorbic acid biosynthetic process
MS7_RS04050	COG0463	Glycosyl transferase, family 2
MS7_RS04085	COG0720	synthase
MS7_RS04095	COG0512	Glutamine amidotransferase of anthranilate synthase
MS7_RS04095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MS7_RS04100	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MS7_RS04135	COG0488	(ABC) transporter
MS7_RS04140	COG0514	ATP-dependent DNA helicase (RecQ)
MS7_RS04145	COG0517	IMP dehydrogenase activity
MS7_RS04145	COG1125	glycine betaine transport
MS7_RS04150	COG1174	glycine betaine transport
MS7_RS04175	COG3104	oligopeptide transport
MS7_RS04195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MS7_RS04200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MS7_RS04210	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7_RS04215	COG4605	iron ion homeostasis
MS7_RS04220	COG4604	ABC transporter, ATP-binding protein
MS7_RS04225	COG4607	ABC-type enterochelin transport system periplasmic component
MS7_RS04280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MS7_RS04285	COG1739	Uncharacterized protein family UPF0029
MS7_RS04295	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MS7_RS04300	COG1040	competence protein
MS7_RS04330	COG1388	LysM domain
MS7_RS04330	COG3942	CHAP domain
MS7_RS04390	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MS7_RS04455	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MS7_RS04460	COG1647	Serine aminopeptidase, S33
MS7_RS04465	COG0557	exoribonuclease II activity
MS7_RS04535	COG1278	Cold shock
MS7_RS04575	COG0406	alpha-ribazole phosphatase activity
MS7_RS04580	COG1279	arginine transmembrane transporter activity
MS7_RS04605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MS7_RS04610	COG1393	Belongs to the ArsC family
MS7_RS04625	COG3878	Protein conserved in bacteria
MS7_RS04630	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MS7_RS04645	COG2011	ABC-type metal ion transport system permease component
MS7_RS04650	COG1464	Belongs to the NlpA lipoprotein family
MS7_RS04665	COG0396	ATPase activity
MS7_RS04670	COG0719	Fe-S assembly protein
MS7_RS04680	COG0822	iron-sulfur transferase activity
MS7_RS04700	COG1253	flavin adenine dinucleotide binding
MS7_RS04715	COG1801	Protein of unknown function DUF72
MS7_RS04720	COG0730	response to heat
MS7_RS04735	COG4470	Protein conserved in bacteria
MS7_RS04745	COG2445	Protein of unknown function DUF86
MS7_RS04775	COG1696	Membrane protein involved in D-alanine export
MS7_RS04785	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MS7_RS04790	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MS7_RS04795	COG4837	Protein of unknown function (DUF1462)
MS7_RS04800	COG1252	NADH dehydrogenase
MS7_RS04810	COG0316	Belongs to the HesB IscA family
MS7_RS04820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MS7_RS04825	COG2056	Na+-H+ antiporter family
MS7_RS04830	COG2050	protein possibly involved in aromatic compounds catabolism
MS7_RS04885	COG1098	S1 RNA binding domain
MS7_RS04890	COG1902	pentaerythritol trinitrate reductase activity
MS7_RS04910	COG0584	glycerophosphoryl diester phosphodiesterase
MS7_RS04930	COG0398	Pfam SNARE associated Golgi protein
MS7_RS04975	COG0561	phosphatase activity
MS7_RS05000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MS7_RS05015	COG1881	PFAM PEBP family protein
MS7_RS05045	COG0601	transmembrane transport
MS7_RS05050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS7_RS05055	COG0444	Belongs to the ABC transporter superfamily
MS7_RS05060	COG4608	Belongs to the ABC transporter superfamily
MS7_RS05070	COG0747	negative chemotaxis
MS7_RS05075	COG0444	Belongs to the ABC transporter superfamily
MS7_RS05080	COG4608	Belongs to the ABC transporter superfamily
MS7_RS05085	COG0601	transmembrane transport
MS7_RS05090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS7_RS05115	COG1164	Oligoendopeptidase f
MS7_RS05125	COG2346	COG2346, Truncated hemoglobins
MS7_RS05140	COG2357	RelA SpoT domain protein
MS7_RS05150	COG0564	pseudouridine synthase activity
MS7_RS05155	COG2239	Acts as a magnesium transporter
MS7_RS05160	COG0475	glutathione-regulated potassium exporter activity
MS7_RS05160	COG0569	domain protein
MS7_RS05170	COG0628	permease
MS7_RS05175	COG1115	amino acid carrier protein
MS7_RS05215	COG0861	Integral membrane protein TerC family
MS7_RS05225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MS7_RS05230	COG0737	Belongs to the 5'-nucleotidase family
MS7_RS05245	COG4903	ComK protein
MS7_RS05260	COG4873	Protein conserved in bacteria
MS7_RS05315	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MS7_RS05325	COG2314	TM2 domain
MS7_RS05330	COG0456	acetyltransferase
MS7_RS05335	COG1575	Belongs to the MenA family. Type 1 subfamily
MS7_RS05340	COG1169	isochorismate synthase
MS7_RS05350	COG2267	carboxylic ester hydrolase activity
MS7_RS05375	COG0436	Aminotransferase
MS7_RS05380	COG3594	Acyltransferase
MS7_RS05410	COG1316	TRANSCRIPTIONal
MS7_RS05415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MS7_RS05455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MS7_RS05470	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MS7_RS05510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MS7_RS05515	COG4172	Belongs to the ABC transporter superfamily
MS7_RS05520	COG4721	ABC-type cobalt transport system, permease component
MS7_RS05540	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MS7_RS05565	COG1271	oxidase subunit
MS7_RS05570	COG1294	oxidase, subunit
MS7_RS05575	COG0569	domain protein
MS7_RS05640	COG1176	ABC-type spermidine putrescine transport system, permease component I
MS7_RS05645	COG1177	transmembrane transport
MS7_RS05650	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MS7_RS05675	COG0483	inositol monophosphate 1-phosphatase activity
MS7_RS05685	COG1217	gtp-binding protein TYPA
MS7_RS05695	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MS7_RS05705	COG0772	Belongs to the SEDS family
MS7_RS05740	COG3679	Belongs to the UPF0342 family
MS7_RS05760	COG0742	ribosomal rna small subunit methyltransferase
MS7_RS05820	COG4509	Sortase family
MS7_RS05835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MS7_RS05865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MS7_RS05865	COG1796	DNA polymerase
MS7_RS05890	COG2009	succinate dehydrogenase
MS7_RS05895	COG1053	succinate dehydrogenase
MS7_RS05900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MS7_RS06025	COG1288	antiporter activity
MS7_RS06060	COG1011	Hydrolase
MS7_RS06085	COG4839	cell division protein FtsL
MS7_RS06090	COG0768	penicillin binding
MS7_RS06105	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MS7_RS06110	COG0849	cell division
MS7_RS06125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MS7_RS06135	COG0762	integral membrane protein
MS7_RS06140	COG2302	S4 RNA-binding domain
MS7_RS06145	COG3599	regulation of cell shape
MS7_RS06155	COG2514	catechol 2,3-dioxygenase activity
MS7_RS06170	COG0564	pseudouridine synthase activity
MS7_RS06180	COG2233	PERMEase
MS7_RS06225	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MS7_RS06240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MS7_RS06245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MS7_RS06255	COG2314	TM2 domain
MS7_RS06270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MS7_RS06270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MS7_RS06280	COG0631	protein serine/threonine phosphatase activity
MS7_RS06295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MS7_RS06310	COG1302	Protein conserved in bacteria
MS7_RS06360	COG1196	nuclear chromosome segregation
MS7_RS06365	COG0552	protein localization to endoplasmic reticulum
MS7_RS06375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MS7_RS06440	COG0758	DNA mediated transformation
MS7_RS06535	COG0195	Participates in both transcription termination and antitermination
MS7_RS06540	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MS7_RS06565	COG0196	riboflavin kinase activity
MS7_RS06590	COG2188	Transcriptional regulator
MS7_RS06595	COG0612	Peptidase, M16
MS7_RS06600	COG0612	Peptidase, M16
MS7_RS06605	COG0300	oxidoreductase activity
MS7_RS06625	COG1058	Belongs to the CinA family
MS7_RS06625	COG1546	Belongs to the CinA family
MS7_RS06645	COG1692	metallophosphoesterase
MS7_RS06650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MS7_RS06650	COG0674	pyruvate-flavodoxin oxidoreductase activity
MS7_RS06655	COG1013	pyruvate-flavodoxin oxidoreductase activity
MS7_RS06690	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MS7_RS06695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MS7_RS06720	COG1923	regulation of RNA biosynthetic process
MS7_RS06730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MS7_RS06735	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MS7_RS06740	COG0789	Transcriptional regulator
MS7_RS06840	COG1525	nuclease
MS7_RS06855	COG0527	aspartate kinase activity
MS7_RS06860	COG0460	homoserine dehydrogenase
MS7_RS06865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MS7_RS06890	COG0833	amino acid
MS7_RS06920	COG2340	Cysteine-rich secretory protein family
MS7_RS06955	COG4846	Membrane protein involved in cytochrome C biogenesis
MS7_RS06975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS7_RS06985	COG0824	Thioesterase
MS7_RS07005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MS7_RS07015	COG1115	amino acid carrier protein
MS7_RS07030	COG0628	permease
MS7_RS07055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MS7_RS07065	COG1363	Peptidase, m42
MS7_RS07070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MS7_RS07075	COG0512	Glutamine amidotransferase of anthranilate synthase
MS7_RS07120	COG0561	phosphatase activity
MS7_RS07165	COG0704	Plays a role in the regulation of phosphate uptake
MS7_RS07175	COG0581	inorganic phosphate transmembrane transporter activity
MS7_RS07180	COG0573	inorganic phosphate transmembrane transporter activity
MS7_RS07205	COG0488	(ABC) transporter
MS7_RS07210	COG0527	aspartate kinase activity
MS7_RS07215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MS7_RS07290	COG4548	von Willebrand factor, type A
MS7_RS07295	COG0714	Associated with various cellular activities
MS7_RS07340	COG0671	phosphoesterase, PA-phosphatase related
MS7_RS07420	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MS7_RS07455	COG0531	amino acid
MS7_RS07470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MS7_RS07475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MS7_RS07495	COG0116	Belongs to the methyltransferase superfamily
MS7_RS07525	COG4499	WXG100 protein secretion system (Wss), protein YukC
MS7_RS07525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MS7_RS07535	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MS7_RS07540	COG3935	DnaD domain protein
MS7_RS07565	COG0438	transferase activity, transferring glycosyl groups
MS7_RS07570	COG1694	Mazg nucleotide pyrophosphohydrolase
MS7_RS07575	COG2738	Putative neutral zinc metallopeptidase
MS7_RS07580	COG4347	Protein of unknown function (DUF1405)
MS7_RS07620	COG0142	geranyltranstransferase activity
MS7_RS07675	COG0492	ferredoxin-NADP+ reductase activity
MS7_RS07690	COG0514	ATP-dependent DNA helicase (RecQ)
MS7_RS07700	COG1141	Ferredoxin
MS7_RS07750	COG1388	LysM domain
MS7_RS07750	COG0860	N-Acetylmuramoyl-L-alanine amidase
MS7_RS07800	COG5412	phage tail tape measure protein
MS7_RS07800	COG3953	SLT domain
MS7_RS08050	COG0582	viral genome integration into host DNA
MS7_RS08070	COG5002	protein histidine kinase activity
MS7_RS08075	COG0745	RESPONSE REGULATOR receiver
MS7_RS08080	COG1187	pseudouridine synthase activity
MS7_RS08105	COG0735	belongs to the Fur family
MS7_RS08110	COG0494	nUDIX hydrolase
MS7_RS08115	COG0667	Aldo Keto reductase
MS7_RS08125	COG4221	oxidoreductase activity
MS7_RS08140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MS7_RS08150	COG0366	Alpha amylase catalytic
MS7_RS08155	COG1609	Transcriptional regulator
MS7_RS08175	COG2195	Cleaves the N-terminal amino acid of tripeptides
MS7_RS08185	COG4129	membrane
MS7_RS08195	COG0508	dehydrogenase complex catalyzes the overall conversion of
MS7_RS08200	COG0022	dehydrogenase e1 component
MS7_RS08205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MS7_RS08210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS7_RS08215	COG0497	DNA recombination
MS7_RS08245	COG1302	Protein conserved in bacteria
MS7_RS08250	COG0439	Biotin carboxylase
MS7_RS08255	COG0511	ligase activity, forming carbon-carbon bonds
MS7_RS08265	COG0006	proline dipeptidase activity
MS7_RS08280	COG0095	Lipoate-protein ligase
MS7_RS08285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MS7_RS08330	COG4537	Required for transformation and DNA binding
MS7_RS08335	COG1459	type II secretion system
MS7_RS08340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MS7_RS08345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MS7_RS08350	COG0011	TIGRFAM Protein of
MS7_RS08355	COG1940	carbohydrate kinase activity
MS7_RS08360	COG4483	Protein conserved in bacteria
MS7_RS08370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MS7_RS08380	COG0768	penicillin binding
MS7_RS08395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MS7_RS08400	COG1121	(ABC) transporter
MS7_RS08410	COG0513	Belongs to the DEAD box helicase family
MS7_RS08420	COG2384	SAM-dependent methyltransferase
MS7_RS08440	COG0517	IMP dehydrogenase activity
MS7_RS08460	COG0295	cytidine deaminase activity
MS7_RS08475	COG1702	phosphate starvation-inducible protein PhoH
MS7_RS08490	COG1030	water channel activity
MS7_RS08500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MS7_RS08505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MS7_RS08535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MS7_RS08555	COG1466	dna polymerase III delta subunit
MS7_RS08560	COG2333	competence protein COMEC
MS7_RS08560	COG0658	competence protein
MS7_RS08565	COG2131	deaminase
MS7_RS08575	COG2226	methyltransferase
MS7_RS08580	COG0799	negative regulation of ribosome biogenesis
MS7_RS08585	COG1713	HD superfamily hydrolase involved in NAD metabolism
MS7_RS08595	COG1534	Rna-binding protein
MS7_RS08605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MS7_RS08610	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MS7_RS08635	COG3177	Filamentation induced by cAMP protein fic
MS7_RS08640	COG1914	H( )-stimulated, divalent metal cation uptake system
MS7_RS08650	COG0439	Biotin carboxylase
MS7_RS08655	COG0511	ligase activity, forming carbon-carbon bonds
MS7_RS08660	COG1984	allophanate hydrolase subunit 2
MS7_RS08665	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MS7_RS08680	COG0826	peptidase U32
MS7_RS08685	COG0826	peptidase U32
MS7_RS08715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MS7_RS08735	COG1104	cysteine desulfurase activity
MS7_RS08740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS7_RS08750	COG3237	CsbD-like
MS7_RS08755	COG1959	2 iron, 2 sulfur cluster binding
MS7_RS08760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MS7_RS08765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MS7_RS08805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MS7_RS08805	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MS7_RS08810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MS7_RS08810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MS7_RS08815	COG1862	Preprotein translocase
MS7_RS08855	COG2868	ribosomal protein
MS7_RS08895	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MS7_RS08905	COG0285	dihydrofolate synthase activity
MS7_RS08915	COG2818	Glycosylase
MS7_RS08950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MS7_RS08985	COG4112	unkown
MS7_RS09010	COG0833	amino acid
MS7_RS09025	COG1484	DNA-dependent DNA replication
MS7_RS09055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MS7_RS09055	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MS7_RS09065	COG5002	protein histidine kinase activity
MS7_RS09070	COG0745	RESPONSE REGULATOR receiver
MS7_RS09085	COG0372	Belongs to the citrate synthase family
MS7_RS09090	COG1113	amino acid transport
MS7_RS09115	COG0281	malic enzyme
MS7_RS09125	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MS7_RS09130	COG4109	DRTGG domain
MS7_RS09170	COG0827	DNA restriction-modification system
MS7_RS09190	COG1104	cysteine desulfurase activity
MS7_RS09205	COG1956	GAF domain-containing protein
MS7_RS09220	COG0584	glycerophosphoryl diester phosphodiesterase
MS7_RS09225	COG1764	response to oxidative stress
MS7_RS09230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MS7_RS09235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MS7_RS09250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7_RS09250	COG1263	PTS System
MS7_RS09255	COG0204	Acyl-transferase
MS7_RS09260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MS7_RS09290	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MS7_RS09295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MS7_RS09300	COG0454	-acetyltransferase
MS7_RS09320	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MS7_RS09320	COG1605	Chorismate mutase
MS7_RS09345	COG1674	ftsk spoiiie
MS7_RS09350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MS7_RS09360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MS7_RS09365	COG1363	Peptidase, m42
MS7_RS09375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MS7_RS09385	COG0510	thiamine kinase activity
MS7_RS09405	COG1187	pseudouridine synthase activity
MS7_RS09410	COG2244	polysaccharide biosynthetic process
MS7_RS09415	COG2081	HI0933 family
MS7_RS09435	COG2814	Major facilitator Superfamily
MS7_RS09440	COG1242	4 iron, 4 sulfur cluster binding
MS7_RS09445	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MS7_RS09455	COG2267	carboxylic ester hydrolase activity
MS7_RS09485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MS7_RS09485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MS7_RS09505	COG5632	N-Acetylmuramoyl-L-alanine amidase
MS7_RS09505	COG4193	domain, Protein
MS7_RS09505	COG3266	domain, Protein
MS7_RS09535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MS7_RS09555	COG0656	L-ascorbic acid biosynthetic process
MS7_RS09575	COG1506	peptidase
MS7_RS09580	COG2816	NAD+ diphosphatase activity
MS7_RS09720	COG1131	(ABC) transporter
MS7_RS09830	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MS7_RS09860	COG1131	(ABC) transporter
MS7_RS09865	COG0537	adenosine 5'-monophosphoramidase activity
MS7_RS09895	COG0420	3'-5' exonuclease activity
MS7_RS09920	COG2197	response regulator
MS7_RS09925	COG2203	Gaf domain
MS7_RS09925	COG4585	Histidine kinase
MS7_RS09930	COG0564	pseudouridine synthase activity
MS7_RS09960	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MS7_RS09965	COG1126	abc transporter atp-binding protein
MS7_RS09970	COG0765	amino acid transport
MS7_RS10135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MS7_RS10140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MS7_RS10150	COG4129	membrane
MS7_RS10170	COG1194	a g-specific adenine glycosylase
MS7_RS10175	COG1988	membrane-bound metal-dependent
MS7_RS10190	COG1388	LysM domain
MS7_RS10190	COG1134	teichoic acid transport
MS7_RS10220	COG0535	radical SAM domain protein
MS7_RS10225	COG1607	acyl-coa hydrolase
MS7_RS10230	COG2309	aminopeptidase activity
MS7_RS10250	COG1295	ribonuclease BN
MS7_RS10385	COG4851	CamS sex pheromone cAM373 precursor
MS7_RS10405	COG4496	protein, YerC YecD
MS7_RS10440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MS7_RS10450	COG0077	Prephenate dehydratase
MS7_RS10460	COG0471	metal ion transport
MS7_RS10470	COG1335	isochorismatase
MS7_RS10485	COG1012	belongs to the aldehyde dehydrogenase family
MS7_RS10535	COG1131	(ABC) transporter
MS7_RS10550	COG1725	Transcriptional regulator
MS7_RS10605	COG0860	N-Acetylmuramoyl-L-alanine amidase
MS7_RS10605	COG1388	LysM domain
MS7_RS10620	COG1388	LysM domain
MS7_RS10620	COG5632	N-Acetylmuramoyl-L-alanine amidase
MS7_RS10720	COG4695	Portal protein
MS7_RS10890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MS7_RS10945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MS7_RS11010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS7_RS11015	COG1621	beta-fructofuranosidase activity
MS7_RS11020	COG1609	Transcriptional regulator
MS7_RS11025	COG0004	ammonium transporteR
MS7_RS11030	COG0425	Belongs to the sulfur carrier protein TusA family
MS7_RS11035	COG2391	methyltransferase activity
MS7_RS11045	COG0488	(ABC) transporter
MS7_RS11055	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MS7_RS11065	COG0456	acetyltransferase
MS7_RS11070	COG1214	PFAM Peptidase M22, glycoprotease
MS7_RS11075	COG0802	atpase or kinase
MS7_RS11090	COG0028	Belongs to the TPP enzyme family
MS7_RS11160	COG2183	response to ionizing radiation
MS7_RS11165	COG1191	sigma factor activity
MS7_RS11175	COG1366	Belongs to the anti-sigma-factor antagonist family
MS7_RS11180	COG2208	phosphoserine phosphatase activity
MS7_RS11215	COG3428	Bacterial PH domain
MS7_RS11245	COG2205	protein histidine kinase activity
MS7_RS11250	COG0745	RESPONSE REGULATOR receiver
MS7_RS11260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MS7_RS11270	COG0772	Belongs to the SEDS family
MS7_RS11285	COG1937	Protein conserved in bacteria
MS7_RS11295	COG1418	mRNA catabolic process
MS7_RS11335	COG0629	single-stranded DNA binding
MS7_RS11410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MS7_RS11435	COG0009	L-threonylcarbamoyladenylate synthase
MS7_RS11440	COG2890	protein-(glutamine-N5) methyltransferase activity
MS7_RS11460	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MS7_RS11520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MS7_RS11570	COG0813	purine-nucleoside phosphorylase activity
MS7_RS11575	COG0783	Belongs to the Dps family
MS7_RS11595	COG1482	cell wall glycoprotein biosynthetic process
MS7_RS11600	COG0702	epimerase
MS7_RS11605	COG0640	Transcriptional regulator
MS7_RS11625	COG0561	phosphatase activity
MS7_RS11630	COG1119	ATPase activity
MS7_RS11645	COG3711	transcriptional antiterminator
MS7_RS11675	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MS7_RS11735	COG0489	protein tyrosine kinase activity
MS7_RS11740	COG2814	Major facilitator Superfamily
MS7_RS11755	COG1272	protein, Hemolysin III
MS7_RS11765	COG1988	membrane-bound metal-dependent
MS7_RS11775	COG3314	Sporulation integral membrane protein YlbJ
MS7_RS11780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7_RS11785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS7_RS11790	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MS7_RS11800	COG3457	Alanine racemase
MS7_RS11805	COG4264	IucA IucC family
MS7_RS11810	COG2814	Major facilitator Superfamily
MS7_RS11835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS7_RS11845	COG2130	NADP-dependent
MS7_RS11910	COG0656	L-ascorbic acid biosynthetic process
MS7_RS11915	COG0789	Transcriptional regulator
MS7_RS11925	COG5492	domain, Protein
MS7_RS11975	COG3527	Alpha-acetolactate decarboxylase
MS7_RS11980	COG0028	Belongs to the TPP enzyme family
MS7_RS11995	COG0384	phenazine biosynthesis protein PhzF
MS7_RS12065	COG0201	protein transport
MS7_RS12180	COG2252	PERMEase
MS7_RS12225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS7_RS12285	COG1763	Mo-molybdopterin cofactor biosynthetic process
MS7_RS12305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MS7_RS12310	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MS7_RS12315	COG4149	molybdate abc transporter
MS7_RS12320	COG0725	ABC transporter, periplasmic molybdate-binding protein
MS7_RS12335	COG1268	BioY protein
MS7_RS12350	COG1960	acyl-CoA dehydrogenase activity
MS7_RS12355	COG4413	Urea transporter
MS7_RS12430	COG1757	Na H antiporter
MS7_RS12445	COG3942	CHAP domain
MS7_RS12515	COG1113	amino acid transport
MS7_RS12535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS7_RS12540	COG0385	Bile acid
MS7_RS12550	COG1263	PTS System
MS7_RS12550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7_RS12555	COG1737	Transcriptional regulator
MS7_RS12575	COG1028	Short-chain dehydrogenase reductase Sdr
MS7_RS12580	COG1473	amidohydrolase
MS7_RS12595	COG0583	DNA-binding transcription factor activity
MS7_RS12615	COG2258	MOSC domain
MS7_RS12635	COG1668	transmembrane transport
MS7_RS12640	COG4152	abc transporter atp-binding protein
MS7_RS12645	COG3152	Membrane
MS7_RS12655	COG0786	glutamate:sodium symporter activity
MS7_RS12665	COG0598	Magnesium transport protein CorA
MS7_RS12680	COG0657	acetylesterase activity
MS7_RS12690	COG2814	Major facilitator Superfamily
MS7_RS12695	COG1566	PFAM secretion protein HlyD family protein
MS7_RS12705	COG2814	Major facilitator Superfamily
MS7_RS12770	COG1620	l-lactate permease
MS7_RS12790	COG0604	alcohol dehydrogenase
MS7_RS12820	COG1511	domain protein
MS7_RS12835	COG1263	PTS System
MS7_RS12835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MS7_RS12850	COG3871	stress protein (general stress protein 26)
MS7_RS12900	COG2181	nitrate reductase activity
MS7_RS12910	COG1140	nitrate reductase beta subunit
MS7_RS12915	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MS7_RS12925	COG2146	nitrite reductase [NAD(P)H] activity
MS7_RS12930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MS7_RS12940	COG0454	-acetyltransferase
MS7_RS12945	COG2116	formate transmembrane transporter activity
MS7_RS12960	COG3443	Belongs to the bacterial solute-binding protein 9 family
MS7_RS12960	COG0803	Belongs to the bacterial solute-binding protein 9 family
MS7_RS12995	COG1126	abc transporter atp-binding protein
MS7_RS13000	COG0765	amino acid transport
MS7_RS13005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS7_RS13010	COG2814	Major facilitator Superfamily
MS7_RS13025	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MS7_RS13070	COG0156	8-amino-7-oxononanoate synthase activity
MS7_RS13080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MS7_RS13085	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MS7_RS13100	COG1132	(ABC) transporter
MS7_RS13105	COG2375	cellular response to nickel ion
MS7_RS13105	COG1132	(ABC) transporter
MS7_RS13125	COG1929	Belongs to the glycerate kinase type-1 family
MS7_RS13135	COG2814	Major facilitator Superfamily
MS7_RS13155	COG1113	amino acid transport
MS7_RS13170	COG0531	amino acid
MS7_RS13195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MS7_RS13205	COG1174	glycine betaine transport
MS7_RS13215	COG1174	glycine betaine transport
MS7_RS13235	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
MS7_RS13240	COG0531	amino acid
MS7_RS13245	COG2272	Belongs to the type-B carboxylesterase lipase family
MS7_RS13250	COG2814	Major facilitator Superfamily
MS7_RS13255	COG0390	transport system, permease component
MS7_RS13260	COG4619	ABC transporter
MS7_RS13265	COG1363	Peptidase, m42
MS7_RS13285	COG4808	Protein conserved in bacteria
MS7_RS13290	COG0069	glutamate synthase activity
MS7_RS13305	COG1124	(ABC) transporter
MS7_RS13310	COG0444	Belongs to the ABC transporter superfamily
MS7_RS13315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS7_RS13345	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MS7_RS13355	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MS7_RS13360	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS7_RS13415	COG0494	nUDIX hydrolase
MS7_RS13455	COG1846	Transcriptional regulator
MS7_RS13490	COG1070	Carbohydrate kinase
MS7_RS13495	COG1802	Transcriptional regulator
MS7_RS13500	COG0789	Transcriptional regulator
MS7_RS13505	COG2357	RelA SpoT domain protein
MS7_RS13510	COG4876	unkown
MS7_RS13520	COG2271	Major facilitator Superfamily
MS7_RS13525	COG0586	Pfam SNARE associated Golgi protein
MS7_RS13535	COG2814	Major facilitator Superfamily
MS7_RS13540	COG1846	Transcriptional regulator
MS7_RS13545	COG1131	(ABC) transporter
MS7_RS13565	COG3949	Membrane
MS7_RS13570	COG0400	carboxylic ester hydrolase activity
MS7_RS13580	COG1846	Transcriptional regulator
MS7_RS13590	COG2514	catechol 2,3-dioxygenase activity
MS7_RS13605	COG0561	phosphatase activity
MS7_RS13610	COG1131	(ABC) transporter
MS7_RS13620	COG3764	Sortase (surface protein transpeptidase)
MS7_RS13640	COG1760	l-serine dehydratase
MS7_RS13645	COG1760	l-serine dehydratase
MS7_RS13660	COG0697	spore germination
MS7_RS13665	COG0657	acetylesterase activity
MS7_RS13685	COG0028	Belongs to the TPP enzyme family
MS7_RS13700	COG0583	DNA-binding transcription factor activity
MS7_RS13710	COG3942	CHAP domain
MS7_RS13720	COG3425	synthase
MS7_RS13730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MS7_RS13755	COG2409	Drug exporters of the RND superfamily
MS7_RS13800	COG0436	Aminotransferase
MS7_RS13830	COG3942	CHAP domain
MS7_RS13835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MS7_RS13835	COG2755	lipolytic protein G-D-S-L family
MS7_RS13935	COG3001	Fructosamine kinase
MS7_RS13940	COG0167	dihydroorotate dehydrogenase activity
MS7_RS13995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MS7_RS14000	COG3527	Alpha-acetolactate decarboxylase
MS7_RS14015	COG0531	amino acid
MS7_RS14045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MS7_RS14065	COG1012	belongs to the aldehyde dehydrogenase family
MS7_RS14075	COG1510	regulation of RNA biosynthetic process
MS7_RS14085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS7_RS14110	COG2851	Citrate transporter
MS7_RS14120	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MS7_RS14130	COG0386	Belongs to the glutathione peroxidase family
MS7_RS14155	COG1136	(ABC) transporter
MS7_RS14160	COG2205	protein histidine kinase activity
MS7_RS14165	COG0745	RESPONSE REGULATOR receiver
MS7_RS14180	COG1785	Belongs to the alkaline phosphatase family
MS7_RS14185	COG1846	Transcriptional regulator
MS7_RS14230	COG1438	arginine binding
MS7_RS14250	COG3711	transcriptional antiterminator
MS7_RS14250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7_RS14255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS7_RS14255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7_RS14255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS7_RS14260	COG1482	cell wall glycoprotein biosynthetic process
MS7_RS14270	COG1705	Flagellar rod assembly protein muramidase FlgJ
MS7_RS14270	COG3942	CHAP domain
MS7_RS14275	COG3433	isochorismatase activity
MS7_RS14275	COG1535	isochorismatase
MS7_RS14290	COG0438	transferase activity, transferring glycosyl groups
MS7_RS14305	COG1073	alpha beta
MS7_RS14325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS7_RS14345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS7_RS14435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MS7_RS14525	COG0471	metal ion transport
MS7_RS14530	COG2962	Rard protein
MS7_RS14540	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MS7_RS14555	COG1136	(ABC) transporter
MS7_RS14560	COG0577	efflux transmembrane transporter activity
MS7_RS14570	COG1278	Cold shock
MS7_RS14590	COG1475	DNA binding