locus-tag	class	description
A7U52_RS00085	COG0551	DNA topoisomerase type I activity
A7U52_RS00085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A7U52_RS00100	COG0551	DNA topoisomerase type I activity
A7U52_RS00155	COG1131	(ABC) transporter
A7U52_RS00165	COG3173	Aminoglycoside phosphotransferase
A7U52_RS00240	COG0604	alcohol dehydrogenase
A7U52_RS00265	COG3682	Transcriptional regulator
A7U52_RS00335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7U52_RS00355	COG4846	Membrane protein involved in cytochrome C biogenesis
A7U52_RS00390	COG2340	Cysteine-rich secretory protein family
A7U52_RS00420	COG0833	amino acid
A7U52_RS00445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A7U52_RS00450	COG0460	homoserine dehydrogenase
A7U52_RS00455	COG0527	aspartate kinase activity
A7U52_RS00470	COG1525	nuclease
A7U52_RS00480	COG2197	response regulator
A7U52_RS00495	COG1131	(ABC) transporter
A7U52_RS00615	COG0789	Transcriptional regulator
A7U52_RS00620	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A7U52_RS00625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A7U52_RS00635	COG1923	regulation of RNA biosynthetic process
A7U52_RS00660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A7U52_RS00665	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A7U52_RS00700	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7U52_RS00705	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7U52_RS00705	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A7U52_RS00710	COG1692	metallophosphoesterase
A7U52_RS00730	COG1546	Belongs to the CinA family
A7U52_RS00730	COG1058	Belongs to the CinA family
A7U52_RS00750	COG0300	oxidoreductase activity
A7U52_RS00755	COG0612	Peptidase, M16
A7U52_RS00760	COG0612	Peptidase, M16
A7U52_RS00765	COG2188	Transcriptional regulator
A7U52_RS00795	COG0196	riboflavin kinase activity
A7U52_RS00820	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A7U52_RS00825	COG0195	Participates in both transcription termination and antitermination
A7U52_RS00925	COG0758	DNA mediated transformation
A7U52_RS00985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A7U52_RS00995	COG0552	protein localization to endoplasmic reticulum
A7U52_RS01000	COG1196	nuclear chromosome segregation
A7U52_RS01040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A7U52_RS01050	COG1302	Protein conserved in bacteria
A7U52_RS01065	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A7U52_RS01080	COG0631	protein serine/threonine phosphatase activity
A7U52_RS01090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7U52_RS01090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7U52_RS01105	COG2314	TM2 domain
A7U52_RS01115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A7U52_RS01120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A7U52_RS01135	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A7U52_RS01180	COG2233	PERMEase
A7U52_RS01190	COG0564	pseudouridine synthase activity
A7U52_RS01210	COG2514	catechol 2,3-dioxygenase activity
A7U52_RS01220	COG3599	regulation of cell shape
A7U52_RS01225	COG2302	S4 RNA-binding domain
A7U52_RS01230	COG0762	integral membrane protein
A7U52_RS01240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A7U52_RS01255	COG0849	cell division
A7U52_RS01260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A7U52_RS01275	COG0768	penicillin binding
A7U52_RS01280	COG4839	cell division protein FtsL
A7U52_RS01305	COG1011	Hydrolase
A7U52_RS01340	COG1288	antiporter activity
A7U52_RS01455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A7U52_RS01460	COG1053	succinate dehydrogenase
A7U52_RS01465	COG2009	succinate dehydrogenase
A7U52_RS01490	COG1796	DNA polymerase
A7U52_RS01490	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7U52_RS01525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A7U52_RS01540	COG4509	Sortase family
A7U52_RS01600	COG0742	ribosomal rna small subunit methyltransferase
A7U52_RS01620	COG3679	Belongs to the UPF0342 family
A7U52_RS01655	COG0772	Belongs to the SEDS family
A7U52_RS01665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A7U52_RS01675	COG1217	gtp-binding protein TYPA
A7U52_RS01685	COG0483	inositol monophosphate 1-phosphatase activity
A7U52_RS01710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A7U52_RS01715	COG1177	transmembrane transport
A7U52_RS01720	COG1176	ABC-type spermidine putrescine transport system, permease component I
A7U52_RS01785	COG0569	domain protein
A7U52_RS01790	COG1294	oxidase, subunit
A7U52_RS01795	COG1271	oxidase subunit
A7U52_RS01820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A7U52_RS01845	COG4721	ABC-type cobalt transport system, permease component
A7U52_RS01850	COG4172	Belongs to the ABC transporter superfamily
A7U52_RS01855	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A7U52_RS01895	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7U52_RS01910	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A7U52_RS01955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7U52_RS01960	COG1316	TRANSCRIPTIONal
A7U52_RS01990	COG3594	Acyltransferase
A7U52_RS01995	COG0436	Aminotransferase
A7U52_RS02020	COG2267	carboxylic ester hydrolase activity
A7U52_RS02030	COG1169	isochorismate synthase
A7U52_RS02040	COG1575	Belongs to the MenA family. Type 1 subfamily
A7U52_RS02045	COG0456	acetyltransferase
A7U52_RS02050	COG2314	TM2 domain
A7U52_RS02060	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A7U52_RS02120	COG4873	Protein conserved in bacteria
A7U52_RS02135	COG4903	ComK protein
A7U52_RS02150	COG0737	Belongs to the 5'-nucleotidase family
A7U52_RS02155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7U52_RS02165	COG0861	Integral membrane protein TerC family
A7U52_RS02205	COG1115	amino acid carrier protein
A7U52_RS02210	COG0628	permease
A7U52_RS02220	COG0569	domain protein
A7U52_RS02220	COG0475	glutathione-regulated potassium exporter activity
A7U52_RS02225	COG2239	Acts as a magnesium transporter
A7U52_RS02230	COG0564	pseudouridine synthase activity
A7U52_RS02240	COG2357	RelA SpoT domain protein
A7U52_RS02255	COG2346	COG2346, Truncated hemoglobins
A7U52_RS02265	COG1164	Oligoendopeptidase f
A7U52_RS02295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U52_RS02300	COG0601	transmembrane transport
A7U52_RS02305	COG4608	Belongs to the ABC transporter superfamily
A7U52_RS02310	COG0444	Belongs to the ABC transporter superfamily
A7U52_RS02315	COG0747	negative chemotaxis
A7U52_RS02320	COG4166	transmembrane transport
A7U52_RS02325	COG4608	Belongs to the ABC transporter superfamily
A7U52_RS02330	COG0444	Belongs to the ABC transporter superfamily
A7U52_RS02335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U52_RS02340	COG0601	transmembrane transport
A7U52_RS02370	COG1881	PFAM PEBP family protein
A7U52_RS02385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7U52_RS02410	COG0561	phosphatase activity
A7U52_RS02450	COG0398	Pfam SNARE associated Golgi protein
A7U52_RS02470	COG0584	glycerophosphoryl diester phosphodiesterase
A7U52_RS02490	COG1902	pentaerythritol trinitrate reductase activity
A7U52_RS02495	COG1098	S1 RNA binding domain
A7U52_RS02550	COG2050	protein possibly involved in aromatic compounds catabolism
A7U52_RS02555	COG2056	Na+-H+ antiporter family
A7U52_RS02560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A7U52_RS02570	COG0316	Belongs to the HesB IscA family
A7U52_RS02580	COG1252	NADH dehydrogenase
A7U52_RS02585	COG4837	Protein of unknown function (DUF1462)
A7U52_RS02590	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A7U52_RS02595	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A7U52_RS02605	COG1696	Membrane protein involved in D-alanine export
A7U52_RS02635	COG2445	Protein of unknown function DUF86
A7U52_RS02645	COG4470	Protein conserved in bacteria
A7U52_RS02660	COG0730	response to heat
A7U52_RS02665	COG1801	Protein of unknown function DUF72
A7U52_RS02680	COG1253	flavin adenine dinucleotide binding
A7U52_RS02705	COG0822	iron-sulfur transferase activity
A7U52_RS02715	COG0719	Fe-S assembly protein
A7U52_RS02720	COG0396	ATPase activity
A7U52_RS02735	COG1464	Belongs to the NlpA lipoprotein family
A7U52_RS02740	COG2011	ABC-type metal ion transport system permease component
A7U52_RS02755	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A7U52_RS02765	COG3878	Protein conserved in bacteria
A7U52_RS02780	COG1393	Belongs to the ArsC family
A7U52_RS02785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7U52_RS02810	COG1279	arginine transmembrane transporter activity
A7U52_RS02815	COG0406	alpha-ribazole phosphatase activity
A7U52_RS02855	COG1278	Cold shock
A7U52_RS02930	COG0557	exoribonuclease II activity
A7U52_RS02935	COG1647	Serine aminopeptidase, S33
A7U52_RS02940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A7U52_RS03005	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A7U52_RS03065	COG3942	CHAP domain
A7U52_RS03065	COG1388	LysM domain
A7U52_RS03095	COG1040	competence protein
A7U52_RS03100	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A7U52_RS03110	COG1739	Uncharacterized protein family UPF0029
A7U52_RS03115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7U52_RS03170	COG4607	ABC-type enterochelin transport system periplasmic component
A7U52_RS03175	COG4604	ABC transporter, ATP-binding protein
A7U52_RS03180	COG4605	iron ion homeostasis
A7U52_RS03185	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U52_RS03205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7U52_RS03210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7U52_RS03240	COG3104	oligopeptide transport
A7U52_RS03270	COG1174	glycine betaine transport
A7U52_RS03275	COG1125	glycine betaine transport
A7U52_RS03275	COG0517	IMP dehydrogenase activity
A7U52_RS03280	COG0514	ATP-dependent DNA helicase (RecQ)
A7U52_RS03285	COG0488	(ABC) transporter
A7U52_RS03315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7U52_RS03320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A7U52_RS03320	COG0512	Glutamine amidotransferase of anthranilate synthase
A7U52_RS03330	COG0720	synthase
A7U52_RS03365	COG0463	Glycosyl transferase, family 2
A7U52_RS03370	COG0656	L-ascorbic acid biosynthetic process
A7U52_RS03375	COG1253	flavin adenine dinucleotide binding
A7U52_RS03380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A7U52_RS03385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U52_RS03385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U52_RS03385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U52_RS03390	COG1105	Belongs to the carbohydrate kinase PfkB family
A7U52_RS03395	COG1349	DNA-binding transcription factor activity
A7U52_RS03400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A7U52_RS03430	COG0415	Belongs to the DNA photolyase family
A7U52_RS03435	COG0471	metal ion transport
A7U52_RS03445	COG4989	oxidoreductase activity
A7U52_RS03450	COG0523	cobalamin synthesis protein
A7U52_RS03460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A7U52_RS03465	COG4988	ABC transporter
A7U52_RS03485	COG1611	Belongs to the LOG family
A7U52_RS03515	COG2839	Protein conserved in bacteria
A7U52_RS03520	COG2814	Major facilitator Superfamily
A7U52_RS03530	COG0583	DNA-binding transcription factor activity
A7U52_RS03560	COG4977	sequence-specific DNA binding
A7U52_RS03560	COG1917	Cupin 2, conserved barrel domain protein
A7U52_RS03570	COG3942	CHAP domain
A7U52_RS03570	COG1388	LysM domain
A7U52_RS03575	COG0306	phosphate transporter
A7U52_RS03580	COG1392	Phosphate transport regulator
A7U52_RS03585	COG0577	efflux transmembrane transporter activity
A7U52_RS03590	COG1136	(ABC) transporter
A7U52_RS03605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7U52_RS03630	COG3949	Membrane
A7U52_RS03640	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
A7U52_RS03650	COG2376	Dihydroxyacetone kinase
A7U52_RS03655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U52_RS03660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U52_RS03665	COG1120	ATPase activity
A7U52_RS03670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7U52_RS03680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7U52_RS03685	COG1132	(ABC) transporter
A7U52_RS03690	COG1686	Belongs to the peptidase S11 family
A7U52_RS03695	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A7U52_RS03700	COG1216	Glycosyl transferase, family 2
A7U52_RS03705	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U52_RS03710	COG1682	transport, permease protein
A7U52_RS03720	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
A7U52_RS03730	COG1321	iron dependent repressor
A7U52_RS03735	COG1121	(ABC) transporter
A7U52_RS03740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7U52_RS03790	COG4974	Belongs to the 'phage' integrase family
A7U52_RS03825	COG2946	Replication initiation factor
A7U52_RS03845	COG0433	COG0433 Predicted ATPase
A7U52_RS03850	COG1674	ftsk spoiiie
A7U52_RS03880	COG2826	transposase and inactivated derivatives, IS30 family
A7U52_RS03920	COG4139	cobalamin transport
A7U52_RS03925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7U52_RS03965	COG1078	dGTPase activity
A7U52_RS03975	COG0655	NAD(P)H dehydrogenase (quinone) activity
A7U52_RS03980	COG0667	Aldo Keto reductase
A7U52_RS04090	COG0083	homoserine kinase activity
A7U52_RS04095	COG0095	Lipoate-protein ligase
A7U52_RS04210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7U52_RS04255	COG0561	phosphatase activity
A7U52_RS04265	COG1428	Deoxynucleoside kinase
A7U52_RS04270	COG1428	Deoxynucleoside kinase
A7U52_RS04275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A7U52_RS04310	COG1473	amidohydrolase
A7U52_RS04350	COG2813	Specifically methylates the guanine in position
A7U52_RS04410	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A7U52_RS04435	COG4956	integral membrane protein (PIN domain superfamily)
A7U52_RS04440	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A7U52_RS04455	COG3880	PFAM UvrB UvrC protein
A7U52_RS04465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7U52_RS04480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7U52_RS04575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A7U52_RS04600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7U52_RS04615	COG1098	S1 RNA binding domain
A7U52_RS04625	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A7U52_RS04630	COG3956	TIGRFAM MazG family protein
A7U52_RS04635	COG2244	polysaccharide biosynthetic process
A7U52_RS04680	COG0251	oxidation-reduction process
A7U52_RS04685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7U52_RS04695	COG4466	Protein conserved in bacteria
A7U52_RS04705	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A7U52_RS04710	COG0084	hydrolase, TatD family'
A7U52_RS04720	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A7U52_RS04730	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A7U52_RS04740	COG1774	PSP1 C-terminal conserved region
A7U52_RS04745	COG0470	DNA polymerase III
A7U52_RS04750	COG3870	Protein conserved in bacteria
A7U52_RS04760	COG1982	Orn Lys Arg decarboxylase major
A7U52_RS04800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A7U52_RS04820	COG2188	Transcriptional regulator
A7U52_RS04825	COG0366	Alpha amylase catalytic
A7U52_RS04830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U52_RS04830	COG1263	PTS System
A7U52_RS04840	COG0493	'glutamate synthase
A7U52_RS04845	COG0067	glutamate synthase
A7U52_RS04845	COG0069	glutamate synthase activity
A7U52_RS04845	COG0070	glutamate synthase
A7U52_RS04850	COG0583	DNA-binding transcription factor activity
A7U52_RS04885	COG1464	Belongs to the NlpA lipoprotein family
A7U52_RS04890	COG2011	ABC-type metal ion transport system permease component
A7U52_RS04900	COG0626	cystathionine gamma-synthase activity
A7U52_RS04905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7U52_RS04910	COG0733	neurotransmitter:sodium symporter activity
A7U52_RS04920	COG1647	Serine aminopeptidase, S33
A7U52_RS04935	COG5609	conserved protein (DUF2294)
A7U52_RS04945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7U52_RS04970	COG0523	cobalamin synthesis protein
A7U52_RS05135	COG3759	membrane
A7U52_RS05175	COG2233	PERMEase
A7U52_RS05210	COG1823	symporter activity
A7U52_RS05225	COG3634	alkyl hydroperoxide reductase activity
A7U52_RS05285	COG4974	Belongs to the 'phage' integrase family
A7U52_RS05320	COG0012	GTP binding
A7U52_RS05325	COG4481	Protein conserved in bacteria
A7U52_RS05330	COG0668	transmembrane transport
A7U52_RS05335	COG1475	DNA binding
A7U52_RS05345	COG0626	cystathionine gamma-synthase activity
A7U52_RS05350	COG0626	cystathionine gamma-synthase activity
A7U52_RS05355	COG0646	methionine synthase
A7U52_RS05355	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A7U52_RS05385	COG1131	(ABC) transporter
A7U52_RS05395	COG1476	TRANSCRIPTIONal
A7U52_RS05405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7U52_RS05410	COG0805	protein transport
A7U52_RS05415	COG0672	)-iron permease
A7U52_RS05430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7U52_RS05445	COG0431	NADPH-dependent FMN reductase
A7U52_RS05450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7U52_RS05455	COG0346	lactoylglutathione lyase activity
A7U52_RS05460	COG2271	Major facilitator Superfamily
A7U52_RS05485	COG3711	transcriptional antiterminator
A7U52_RS05490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U52_RS05500	COG3037	sugar-specific permease SgaT UlaA
A7U52_RS05530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7U52_RS05555	COG3314	Sporulation integral membrane protein YlbJ
A7U52_RS05580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7U52_RS05585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7U52_RS05615	COG0577	efflux transmembrane transporter activity
A7U52_RS05625	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A7U52_RS05635	COG1114	Component of the transport system for branched-chain amino acids
A7U52_RS05785	COG1388	LysM domain
A7U52_RS05785	COG3942	CHAP domain
A7U52_RS05815	COG1131	(ABC) transporter
A7U52_RS05875	COG2226	methyltransferase
A7U52_RS05885	COG2723	6-phospho-beta-galactosidase activity
A7U52_RS05890	COG2190	(PTS) system
A7U52_RS05890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U52_RS05890	COG1263	PTS System
A7U52_RS05900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7U52_RS05935	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U52_RS05940	COG1063	alcohol dehydrogenase
A7U52_RS05950	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U52_RS05955	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U52_RS05960	COG1063	alcohol dehydrogenase
A7U52_RS05970	COG1063	alcohol dehydrogenase
A7U52_RS05980	COG1063	alcohol dehydrogenase
A7U52_RS05985	COG3775	system Galactitol-specific IIC component
A7U52_RS05990	COG3414	Phosphotransferase system galactitol-specific IIB component
A7U52_RS06010	COG1957	nucleoside hydrolase
A7U52_RS06015	COG1263	PTS System
A7U52_RS06015	COG2190	(PTS) system
A7U52_RS06015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U52_RS06050	COG3189	MarR family transcriptional regulator
A7U52_RS06055	COG0747	negative chemotaxis
A7U52_RS06070	COG0318	PFAM AMP-dependent synthetase and ligase
A7U52_RS06075	COG1960	acyl-CoA dehydrogenase activity
A7U52_RS06085	COG0183	Belongs to the thiolase family
A7U52_RS06145	COG1755	Isoprenylcysteine carboxyl methyltransferase
A7U52_RS06155	COG0673	inositol 2-dehydrogenase activity
A7U52_RS06160	COG0673	inositol 2-dehydrogenase activity
A7U52_RS06165	COG3833	ABC-type maltose transport systems, permease component
A7U52_RS06170	COG1175	transmembrane transport
A7U52_RS06180	COG3842	ATPase activity
A7U52_RS06200	COG0405	Gamma-glutamyltransferase
A7U52_RS06210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U52_RS06215	COG0601	transmembrane transport
A7U52_RS06250	COG1737	Transcriptional regulator
A7U52_RS06280	COG3961	Belongs to the TPP enzyme family
A7U52_RS06285	COG1335	isochorismatase
A7U52_RS06290	COG1114	Component of the transport system for branched-chain amino acids
A7U52_RS06340	COG5609	conserved protein (DUF2294)
A7U52_RS06345	COG1960	acyl-CoA dehydrogenase activity
A7U52_RS06350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7U52_RS06385	COG2832	Protein of unknown function (DUF454)
A7U52_RS06395	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7U52_RS06400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A7U52_RS06410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7U52_RS06440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7U52_RS06450	COG1086	Polysaccharide biosynthesis protein
A7U52_RS06475	COG1454	alcohol dehydrogenase
A7U52_RS06475	COG1012	belongs to the aldehyde dehydrogenase family
A7U52_RS06505	COG0737	Belongs to the 5'-nucleotidase family
A7U52_RS06525	COG3639	organic phosphonate transmembrane transporter activity
A7U52_RS06545	COG2814	Major facilitator Superfamily
A7U52_RS06550	COG0813	purine-nucleoside phosphorylase activity
A7U52_RS06585	COG0438	transferase activity, transferring glycosyl groups
A7U52_RS06590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7U52_RS06595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7U52_RS06625	COG1475	DNA binding
A7U52_RS06630	COG0019	diaminopimelate decarboxylase activity
A7U52_RS06640	COG4264	IucA IucC family
A7U52_RS06645	COG4264	IucA IucC family
A7U52_RS06650	COG2814	Major facilitator Superfamily
A7U52_RS06655	COG4264	IucA IucC family
A7U52_RS06660	COG2423	ornithine cyclodeaminase activity
A7U52_RS06670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7U52_RS06675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U52_RS06680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U52_RS06700	COG1620	l-lactate permease
A7U52_RS06715	COG0697	spore germination
A7U52_RS06720	COG4716	Myosin-crossreactive antigen
A7U52_RS06725	COG1283	sodium-dependent phosphate transmembrane transporter activity
A7U52_RS06735	COG1473	amidohydrolase
A7U52_RS06765	COG0823	Involved in the tonB-independent uptake of proteins
A7U52_RS06785	COG0583	DNA-binding transcription factor activity
A7U52_RS06800	COG0655	NAD(P)H dehydrogenase (quinone) activity
A7U52_RS06845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7U52_RS06850	COG2210	Belongs to the sulfur carrier protein TusA family
A7U52_RS06855	COG1937	Protein conserved in bacteria
A7U52_RS06860	COG0730	response to heat
A7U52_RS06890	COG1388	LysM domain
A7U52_RS06900	COG1124	(ABC) transporter
A7U52_RS06905	COG4172	Belongs to the ABC transporter superfamily
A7U52_RS06910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U52_RS06960	COG2235	arginine
A7U52_RS06970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7U52_RS06975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A7U52_RS07025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7U52_RS07030	COG2801	Transposase and inactivated derivatives
A7U52_RS07150	COG2030	dehydratase
A7U52_RS07155	COG0584	glycerophosphoryl diester phosphodiesterase
A7U52_RS07165	COG3425	synthase
A7U52_RS07185	COG0737	Belongs to the 5'-nucleotidase family
A7U52_RS07190	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A7U52_RS07200	COG4863	YycH protein
A7U52_RS07235	COG0305	Participates in initiation and elongation during chromosome replication
A7U52_RS07245	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A7U52_RS07255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A7U52_RS07285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A7U52_RS07305	COG2501	S4 domain
A7U52_RS07345	COG1475	DNA binding
A7U52_RS07370	COG1278	Cold shock
A7U52_RS07400	COG0577	efflux transmembrane transporter activity
A7U52_RS07405	COG1136	(ABC) transporter
A7U52_RS07420	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A7U52_RS07430	COG2962	Rard protein
A7U52_RS07435	COG0471	metal ion transport
A7U52_RS07520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7U52_RS07555	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A7U52_RS07610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7U52_RS07630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7U52_RS07650	COG1073	alpha beta
A7U52_RS07665	COG0438	transferase activity, transferring glycosyl groups
A7U52_RS07680	COG3433	isochorismatase activity
A7U52_RS07680	COG1535	isochorismatase
A7U52_RS07685	COG3942	CHAP domain
A7U52_RS07685	COG1705	Flagellar rod assembly protein muramidase FlgJ
A7U52_RS07695	COG1482	cell wall glycoprotein biosynthetic process
A7U52_RS07700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U52_RS07700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U52_RS07700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U52_RS07705	COG3711	transcriptional antiterminator
A7U52_RS07705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U52_RS07725	COG1438	arginine binding
A7U52_RS07770	COG1846	Transcriptional regulator
A7U52_RS07780	COG1785	Belongs to the alkaline phosphatase family
A7U52_RS07790	COG0745	RESPONSE REGULATOR receiver
A7U52_RS07795	COG2205	protein histidine kinase activity
A7U52_RS07800	COG1136	(ABC) transporter
A7U52_RS07825	COG0386	Belongs to the glutathione peroxidase family
A7U52_RS07835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A7U52_RS07850	COG2851	Citrate transporter
A7U52_RS07875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7U52_RS07885	COG1510	regulation of RNA biosynthetic process
A7U52_RS07895	COG1012	belongs to the aldehyde dehydrogenase family
A7U52_RS07915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7U52_RS07945	COG0531	amino acid
A7U52_RS07960	COG3527	Alpha-acetolactate decarboxylase
A7U52_RS07965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7U52_RS08015	COG0167	dihydroorotate dehydrogenase activity
A7U52_RS08020	COG3001	Fructosamine kinase
A7U52_RS08130	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A7U52_RS08130	COG2755	lipolytic protein G-D-S-L family
A7U52_RS08135	COG3942	CHAP domain
A7U52_RS08165	COG0436	Aminotransferase
A7U52_RS08210	COG2409	Drug exporters of the RND superfamily
A7U52_RS08230	COG0542	response to heat
A7U52_RS08235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7U52_RS08240	COG3425	synthase
A7U52_RS08265	COG3942	CHAP domain
A7U52_RS08275	COG0583	DNA-binding transcription factor activity
A7U52_RS08290	COG0028	Belongs to the TPP enzyme family
A7U52_RS08310	COG0657	acetylesterase activity
A7U52_RS08315	COG0697	spore germination
A7U52_RS08330	COG1760	l-serine dehydratase
A7U52_RS08335	COG1760	l-serine dehydratase
A7U52_RS08355	COG3764	Sortase (surface protein transpeptidase)
A7U52_RS08365	COG1131	(ABC) transporter
A7U52_RS08370	COG0561	phosphatase activity
A7U52_RS08385	COG2514	catechol 2,3-dioxygenase activity
A7U52_RS08395	COG1846	Transcriptional regulator
A7U52_RS08400	COG0346	lactoylglutathione lyase activity
A7U52_RS08405	COG0400	carboxylic ester hydrolase activity
A7U52_RS08425	COG1131	(ABC) transporter
A7U52_RS08440	COG1846	Transcriptional regulator
A7U52_RS08445	COG2814	Major facilitator Superfamily
A7U52_RS08455	COG0586	Pfam SNARE associated Golgi protein
A7U52_RS08460	COG2271	Major facilitator Superfamily
A7U52_RS08470	COG4876	unkown
A7U52_RS08475	COG2357	RelA SpoT domain protein
A7U52_RS08480	COG0789	Transcriptional regulator
A7U52_RS08485	COG1802	Transcriptional regulator
A7U52_RS08490	COG1070	Carbohydrate kinase
A7U52_RS08525	COG1846	Transcriptional regulator
A7U52_RS08530	COG1846	Transcriptional regulator
A7U52_RS08570	COG0494	nUDIX hydrolase
A7U52_RS08660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7U52_RS08665	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A7U52_RS08695	COG0747	negative chemotaxis
A7U52_RS08700	COG0601	transmembrane transport
A7U52_RS08705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U52_RS08710	COG0444	Belongs to the ABC transporter superfamily
A7U52_RS08715	COG1124	(ABC) transporter
A7U52_RS08730	COG0069	glutamate synthase activity
A7U52_RS08735	COG4808	Protein conserved in bacteria
A7U52_RS08755	COG1363	Peptidase, m42
A7U52_RS08760	COG4619	ABC transporter
A7U52_RS08765	COG0390	transport system, permease component
A7U52_RS08770	COG2814	Major facilitator Superfamily
A7U52_RS08775	COG2272	Belongs to the type-B carboxylesterase lipase family
A7U52_RS08780	COG0531	amino acid
A7U52_RS08790	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
A7U52_RS08810	COG1174	glycine betaine transport
A7U52_RS08820	COG1174	glycine betaine transport
A7U52_RS08830	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7U52_RS08855	COG0531	amino acid
A7U52_RS08870	COG1113	amino acid transport
A7U52_RS08890	COG2814	Major facilitator Superfamily
A7U52_RS08900	COG1929	Belongs to the glycerate kinase type-1 family
A7U52_RS08920	COG1132	(ABC) transporter
A7U52_RS08920	COG2375	cellular response to nickel ion
A7U52_RS08925	COG1132	(ABC) transporter
A7U52_RS08940	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A7U52_RS08945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7U52_RS08955	COG0156	8-amino-7-oxononanoate synthase activity
A7U52_RS09005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7U52_RS09025	COG2814	Major facilitator Superfamily
A7U52_RS09030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7U52_RS09035	COG0765	amino acid transport
A7U52_RS09040	COG1126	abc transporter atp-binding protein
A7U52_RS09080	COG3443	Belongs to the bacterial solute-binding protein 9 family
A7U52_RS09080	COG0803	Belongs to the bacterial solute-binding protein 9 family
A7U52_RS09095	COG2116	formate transmembrane transporter activity
A7U52_RS09100	COG0454	-acetyltransferase
A7U52_RS09110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7U52_RS09115	COG2146	nitrite reductase [NAD(P)H] activity
A7U52_RS09125	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A7U52_RS09130	COG1140	nitrate reductase beta subunit
A7U52_RS09140	COG2181	nitrate reductase activity
A7U52_RS09160	COG0789	Transcriptional regulator
A7U52_RS09200	COG3871	stress protein (general stress protein 26)
A7U52_RS09215	COG1263	PTS System
A7U52_RS09215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U52_RS09230	COG1511	domain protein
A7U52_RS09255	COG0456	acetyltransferase
A7U52_RS09260	COG0604	alcohol dehydrogenase
A7U52_RS09280	COG1620	l-lactate permease
A7U52_RS09350	COG2814	Major facilitator Superfamily
A7U52_RS09360	COG1566	PFAM secretion protein HlyD family protein
A7U52_RS09365	COG2814	Major facilitator Superfamily
A7U52_RS09375	COG0657	acetylesterase activity
A7U52_RS09390	COG0598	Magnesium transport protein CorA
A7U52_RS09400	COG0786	glutamate:sodium symporter activity
A7U52_RS09415	COG3152	Membrane
A7U52_RS09420	COG4152	abc transporter atp-binding protein
A7U52_RS09425	COG1668	transmembrane transport
A7U52_RS09445	COG2258	MOSC domain
A7U52_RS09470	COG0583	DNA-binding transcription factor activity
A7U52_RS09485	COG1473	amidohydrolase
A7U52_RS09490	COG1028	Short-chain dehydrogenase reductase Sdr
A7U52_RS09510	COG1737	Transcriptional regulator
A7U52_RS09515	COG1263	PTS System
A7U52_RS09515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U52_RS09525	COG0385	Bile acid
A7U52_RS09530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7U52_RS09550	COG1113	amino acid transport
A7U52_RS09625	COG3942	CHAP domain
A7U52_RS09640	COG1757	Na H antiporter
A7U52_RS09650	COG3942	CHAP domain
A7U52_RS09715	COG4413	Urea transporter
A7U52_RS09720	COG1960	acyl-CoA dehydrogenase activity
A7U52_RS09735	COG1268	BioY protein
A7U52_RS09750	COG0725	ABC transporter, periplasmic molybdate-binding protein
A7U52_RS09755	COG4149	molybdate abc transporter
A7U52_RS09760	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A7U52_RS09765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7U52_RS09785	COG1763	Mo-molybdopterin cofactor biosynthetic process
A7U52_RS09860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A7U52_RS09905	COG2252	PERMEase
A7U52_RS10020	COG0201	protein transport
A7U52_RS10105	COG0542	response to heat
A7U52_RS10125	COG0028	Belongs to the TPP enzyme family
A7U52_RS10130	COG3527	Alpha-acetolactate decarboxylase
A7U52_RS10150	COG5492	domain, Protein
A7U52_RS10160	COG0789	Transcriptional regulator
A7U52_RS10165	COG0656	L-ascorbic acid biosynthetic process
A7U52_RS10185	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A7U52_RS10235	COG2130	NADP-dependent
A7U52_RS10245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7U52_RS10275	COG2814	Major facilitator Superfamily
A7U52_RS10280	COG4264	IucA IucC family
A7U52_RS10285	COG3457	Alanine racemase
A7U52_RS10295	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A7U52_RS10300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U52_RS10305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U52_RS10310	COG3314	Sporulation integral membrane protein YlbJ
A7U52_RS10320	COG1988	membrane-bound metal-dependent
A7U52_RS10330	COG1272	protein, Hemolysin III
A7U52_RS10345	COG2814	Major facilitator Superfamily
A7U52_RS10350	COG0489	protein tyrosine kinase activity
A7U52_RS10425	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A7U52_RS10455	COG3711	transcriptional antiterminator
A7U52_RS10470	COG1119	ATPase activity
A7U52_RS10475	COG0561	phosphatase activity
A7U52_RS10510	COG0640	Transcriptional regulator
A7U52_RS10515	COG0702	epimerase
A7U52_RS10520	COG1482	cell wall glycoprotein biosynthetic process
A7U52_RS10540	COG0783	Belongs to the Dps family
A7U52_RS10545	COG0813	purine-nucleoside phosphorylase activity
A7U52_RS10595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7U52_RS10635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A7U52_RS10660	COG2890	protein-(glutamine-N5) methyltransferase activity
A7U52_RS10665	COG0009	L-threonylcarbamoyladenylate synthase
A7U52_RS10690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7U52_RS10765	COG0629	single-stranded DNA binding
A7U52_RS10815	COG1418	mRNA catabolic process
A7U52_RS10825	COG1937	Protein conserved in bacteria
A7U52_RS10840	COG0772	Belongs to the SEDS family
A7U52_RS10850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A7U52_RS10860	COG0745	RESPONSE REGULATOR receiver
A7U52_RS10865	COG2205	protein histidine kinase activity
A7U52_RS10895	COG3428	Bacterial PH domain
A7U52_RS10930	COG2208	phosphoserine phosphatase activity
A7U52_RS10935	COG1366	Belongs to the anti-sigma-factor antagonist family
A7U52_RS10945	COG1191	sigma factor activity
A7U52_RS10950	COG2183	response to ionizing radiation
A7U52_RS11025	COG0028	Belongs to the TPP enzyme family
A7U52_RS11040	COG0802	atpase or kinase
A7U52_RS11045	COG1214	PFAM Peptidase M22, glycoprotease
A7U52_RS11050	COG0456	acetyltransferase
A7U52_RS11060	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A7U52_RS11070	COG0488	(ABC) transporter
A7U52_RS11080	COG2391	methyltransferase activity
A7U52_RS11085	COG0425	Belongs to the sulfur carrier protein TusA family
A7U52_RS11090	COG0004	ammonium transporteR
A7U52_RS11095	COG1609	Transcriptional regulator
A7U52_RS11100	COG1621	beta-fructofuranosidase activity
A7U52_RS11105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7U52_RS11180	COG5484	DNA packaging
A7U52_RS11180	COG3728	DNA packaging
A7U52_RS11200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7U52_RS11205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7U52_RS11210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7U52_RS11260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A7U52_RS11435	COG0740	serine-type endopeptidase activity
A7U52_RS11485	COG0739	heme binding
A7U52_RS11530	COG1388	LysM domain
A7U52_RS11530	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7U52_RS11545	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7U52_RS11545	COG1388	LysM domain
A7U52_RS11605	COG1725	Transcriptional regulator
A7U52_RS11620	COG1131	(ABC) transporter
A7U52_RS11675	COG1012	belongs to the aldehyde dehydrogenase family
A7U52_RS11690	COG1335	isochorismatase
A7U52_RS11710	COG0077	Prephenate dehydratase
A7U52_RS11720	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A7U52_RS11760	COG4496	protein, YerC YecD
A7U52_RS11770	COG0210	DNA helicase
A7U52_RS11780	COG4851	CamS sex pheromone cAM373 precursor
A7U52_RS11910	COG2197	response regulator
A7U52_RS11915	COG1295	ribonuclease BN
A7U52_RS11935	COG2309	aminopeptidase activity
A7U52_RS11940	COG1607	acyl-coa hydrolase
A7U52_RS11945	COG0535	radical SAM domain protein
A7U52_RS11975	COG1134	teichoic acid transport
A7U52_RS11975	COG1388	LysM domain
A7U52_RS11990	COG1988	membrane-bound metal-dependent
A7U52_RS12015	COG4129	membrane
A7U52_RS12025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A7U52_RS12030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7U52_RS12210	COG0765	amino acid transport
A7U52_RS12215	COG1126	abc transporter atp-binding protein
A7U52_RS12220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A7U52_RS12260	COG0564	pseudouridine synthase activity
A7U52_RS12265	COG2203	Gaf domain
A7U52_RS12265	COG4585	Histidine kinase
A7U52_RS12270	COG2197	response regulator
A7U52_RS12300	COG0420	3'-5' exonuclease activity
A7U52_RS12335	COG0537	adenosine 5'-monophosphoramidase activity
A7U52_RS12340	COG1131	(ABC) transporter
A7U52_RS12370	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A7U52_RS12490	COG1131	(ABC) transporter
A7U52_RS12670	COG1506	peptidase
A7U52_RS12695	COG0656	L-ascorbic acid biosynthetic process
A7U52_RS12720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A7U52_RS12750	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7U52_RS12750	COG3266	domain, Protein
A7U52_RS12750	COG4193	domain, Protein
A7U52_RS12775	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7U52_RS12775	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7U52_RS12810	COG2267	carboxylic ester hydrolase activity
A7U52_RS12825	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A7U52_RS12830	COG1242	4 iron, 4 sulfur cluster binding
A7U52_RS12835	COG2814	Major facilitator Superfamily
A7U52_RS12855	COG2081	HI0933 family
A7U52_RS12860	COG2244	polysaccharide biosynthetic process
A7U52_RS12865	COG1187	pseudouridine synthase activity
A7U52_RS12890	COG0510	thiamine kinase activity
A7U52_RS12900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7U52_RS12910	COG1363	Peptidase, m42
A7U52_RS12915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7U52_RS12925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7U52_RS12930	COG1674	ftsk spoiiie
A7U52_RS12955	COG1605	Chorismate mutase
A7U52_RS12955	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A7U52_RS12975	COG0454	-acetyltransferase
A7U52_RS12980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7U52_RS13010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7U52_RS13015	COG0204	Acyl-transferase
A7U52_RS13020	COG1263	PTS System
A7U52_RS13020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U52_RS13035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7U52_RS13040	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A7U52_RS13045	COG1764	response to oxidative stress
A7U52_RS13050	COG0584	glycerophosphoryl diester phosphodiesterase
A7U52_RS13070	COG1956	GAF domain-containing protein
A7U52_RS13085	COG1104	cysteine desulfurase activity
A7U52_RS13105	COG0827	DNA restriction-modification system
A7U52_RS13145	COG4109	DRTGG domain
A7U52_RS13155	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A7U52_RS13165	COG0281	malic enzyme
A7U52_RS13195	COG1113	amino acid transport
A7U52_RS13200	COG0372	Belongs to the citrate synthase family
A7U52_RS13215	COG0745	RESPONSE REGULATOR receiver
A7U52_RS13220	COG5002	protein histidine kinase activity
A7U52_RS13230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7U52_RS13230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7U52_RS13260	COG1484	DNA-dependent DNA replication
A7U52_RS13275	COG0833	amino acid
A7U52_RS13300	COG4112	unkown
A7U52_RS13335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A7U52_RS13370	COG2818	Glycosylase
A7U52_RS13380	COG0285	dihydrofolate synthase activity
A7U52_RS13390	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A7U52_RS13435	COG2868	ribosomal protein
A7U52_RS13475	COG1862	Preprotein translocase
A7U52_RS13480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7U52_RS13480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7U52_RS13485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A7U52_RS13485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A7U52_RS13530	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A7U52_RS13535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A7U52_RS13540	COG1959	2 iron, 2 sulfur cluster binding
A7U52_RS13555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7U52_RS13560	COG1104	cysteine desulfurase activity
A7U52_RS13575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A7U52_RS13605	COG0826	peptidase U32
A7U52_RS13610	COG0826	peptidase U32
A7U52_RS13625	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A7U52_RS13630	COG1984	allophanate hydrolase subunit 2
A7U52_RS13635	COG0511	ligase activity, forming carbon-carbon bonds
A7U52_RS13640	COG0439	Biotin carboxylase
A7U52_RS13650	COG1914	H( )-stimulated, divalent metal cation uptake system
A7U52_RS13655	COG3177	Filamentation induced by cAMP protein fic
A7U52_RS13675	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A7U52_RS13680	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A7U52_RS13690	COG1534	Rna-binding protein
A7U52_RS13700	COG1713	HD superfamily hydrolase involved in NAD metabolism
A7U52_RS13705	COG0799	negative regulation of ribosome biogenesis
A7U52_RS13710	COG2226	methyltransferase
A7U52_RS13720	COG2131	deaminase
A7U52_RS13725	COG2333	competence protein COMEC
A7U52_RS13725	COG0658	competence protein
A7U52_RS13730	COG1466	dna polymerase III delta subunit
A7U52_RS13750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7U52_RS13780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A7U52_RS13785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7U52_RS13795	COG1030	water channel activity
A7U52_RS13810	COG1702	phosphate starvation-inducible protein PhoH
A7U52_RS13825	COG0295	cytidine deaminase activity
A7U52_RS13845	COG0517	IMP dehydrogenase activity
A7U52_RS13865	COG2384	SAM-dependent methyltransferase
A7U52_RS13875	COG0513	Belongs to the DEAD box helicase family
A7U52_RS13885	COG1121	(ABC) transporter
A7U52_RS13890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7U52_RS13905	COG0768	penicillin binding
A7U52_RS13915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A7U52_RS13925	COG4483	Protein conserved in bacteria
A7U52_RS13930	COG1940	carbohydrate kinase activity
A7U52_RS13935	COG0011	TIGRFAM Protein of
A7U52_RS13940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7U52_RS13945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A7U52_RS13950	COG1459	type II secretion system
A7U52_RS13955	COG4537	Required for transformation and DNA binding
A7U52_RS14000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7U52_RS14005	COG0095	Lipoate-protein ligase
A7U52_RS14020	COG0006	proline dipeptidase activity
A7U52_RS14030	COG0511	ligase activity, forming carbon-carbon bonds
A7U52_RS14035	COG0439	Biotin carboxylase
A7U52_RS14040	COG1302	Protein conserved in bacteria
A7U52_RS14070	COG0497	DNA recombination
A7U52_RS14075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7U52_RS14080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A7U52_RS14085	COG0022	dehydrogenase e1 component
A7U52_RS14090	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7U52_RS14100	COG4129	membrane
A7U52_RS14110	COG2195	Cleaves the N-terminal amino acid of tripeptides
A7U52_RS14130	COG1609	Transcriptional regulator
A7U52_RS14135	COG0366	Alpha amylase catalytic
A7U52_RS14145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A7U52_RS14160	COG4221	oxidoreductase activity
A7U52_RS14170	COG0667	Aldo Keto reductase
A7U52_RS14175	COG0494	nUDIX hydrolase
A7U52_RS14180	COG0735	belongs to the Fur family
A7U52_RS14205	COG1187	pseudouridine synthase activity
A7U52_RS14210	COG0745	RESPONSE REGULATOR receiver
A7U52_RS14215	COG5002	protein histidine kinase activity
A7U52_RS14235	COG0582	viral genome integration into host DNA
A7U52_RS14495	COG5280	Phage tail tape measure protein TP901
A7U52_RS14495	COG3953	SLT domain
A7U52_RS14545	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7U52_RS14545	COG1388	LysM domain
A7U52_RS14595	COG1141	Ferredoxin
A7U52_RS14605	COG0514	ATP-dependent DNA helicase (RecQ)
A7U52_RS14620	COG0492	ferredoxin-NADP+ reductase activity
A7U52_RS14685	COG0142	geranyltranstransferase activity
A7U52_RS14725	COG4347	Protein of unknown function (DUF1405)
A7U52_RS14730	COG2738	Putative neutral zinc metallopeptidase
A7U52_RS14735	COG1694	Mazg nucleotide pyrophosphohydrolase
A7U52_RS14740	COG0438	transferase activity, transferring glycosyl groups
A7U52_RS14765	COG3935	DnaD domain protein
A7U52_RS14770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A7U52_RS14780	COG4499	WXG100 protein secretion system (Wss), protein YukC
A7U52_RS14780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7U52_RS14820	COG0116	Belongs to the methyltransferase superfamily
A7U52_RS14835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A7U52_RS14840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7U52_RS14855	COG0531	amino acid
A7U52_RS14880	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A7U52_RS14955	COG0671	phosphoesterase, PA-phosphatase related
A7U52_RS15010	COG4548	von Willebrand factor, type A
A7U52_RS15090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A7U52_RS15095	COG0527	aspartate kinase activity
A7U52_RS15100	COG0488	(ABC) transporter
A7U52_RS15120	COG0573	inorganic phosphate transmembrane transporter activity
A7U52_RS15125	COG0581	inorganic phosphate transmembrane transporter activity
A7U52_RS15135	COG0704	Plays a role in the regulation of phosphate uptake
A7U52_RS15180	COG0561	phosphatase activity
A7U52_RS15220	COG0512	Glutamine amidotransferase of anthranilate synthase
A7U52_RS15225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7U52_RS15230	COG1363	Peptidase, m42
A7U52_RS15240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A7U52_RS15260	COG0392	lysyltransferase activity
A7U52_RS15260	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A7U52_RS15265	COG0628	permease
A7U52_RS15280	COG1115	amino acid carrier protein
A7U52_RS15320	COG0824	Thioesterase