locus-tag	class	description
A7U47_RS00040	COG0604	alcohol dehydrogenase
A7U47_RS00065	COG3682	Transcriptional regulator
A7U47_RS00090	COG0456	acetyltransferase
A7U47_RS00105	COG1968	undecaprenyl-diphosphatase activity
A7U47_RS00140	COG3173	Aminoglycoside phosphotransferase
A7U47_RS00155	COG3093	addiction module antidote protein HigA
A7U47_RS00195	COG0604	alcohol dehydrogenase
A7U47_RS00220	COG3682	Transcriptional regulator
A7U47_RS00235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7U47_RS00255	COG4846	Membrane protein involved in cytochrome C biogenesis
A7U47_RS00290	COG2340	Cysteine-rich secretory protein family
A7U47_RS00320	COG0833	amino acid
A7U47_RS00345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A7U47_RS00350	COG0460	homoserine dehydrogenase
A7U47_RS00355	COG0527	aspartate kinase activity
A7U47_RS00370	COG1525	nuclease
A7U47_RS00380	COG2197	response regulator
A7U47_RS00395	COG1131	(ABC) transporter
A7U47_RS00515	COG0789	Transcriptional regulator
A7U47_RS00520	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A7U47_RS00525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A7U47_RS00535	COG1923	regulation of RNA biosynthetic process
A7U47_RS00560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A7U47_RS00565	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A7U47_RS00600	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7U47_RS00605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A7U47_RS00605	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7U47_RS00610	COG1692	metallophosphoesterase
A7U47_RS00630	COG1058	Belongs to the CinA family
A7U47_RS00630	COG1546	Belongs to the CinA family
A7U47_RS00650	COG0300	oxidoreductase activity
A7U47_RS00655	COG0612	Peptidase, M16
A7U47_RS00660	COG0612	Peptidase, M16
A7U47_RS00665	COG2188	Transcriptional regulator
A7U47_RS00695	COG0196	riboflavin kinase activity
A7U47_RS00720	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A7U47_RS00725	COG0195	Participates in both transcription termination and antitermination
A7U47_RS00825	COG0758	DNA mediated transformation
A7U47_RS00885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A7U47_RS00895	COG0552	protein localization to endoplasmic reticulum
A7U47_RS00900	COG1196	nuclear chromosome segregation
A7U47_RS00940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A7U47_RS00950	COG1302	Protein conserved in bacteria
A7U47_RS00965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A7U47_RS00980	COG0631	protein serine/threonine phosphatase activity
A7U47_RS00990	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7U47_RS00990	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7U47_RS01005	COG2314	TM2 domain
A7U47_RS01015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A7U47_RS01020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A7U47_RS01035	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A7U47_RS01080	COG2233	PERMEase
A7U47_RS01090	COG0564	pseudouridine synthase activity
A7U47_RS01110	COG2514	catechol 2,3-dioxygenase activity
A7U47_RS01120	COG3599	regulation of cell shape
A7U47_RS01125	COG2302	S4 RNA-binding domain
A7U47_RS01130	COG0762	integral membrane protein
A7U47_RS01140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A7U47_RS01155	COG0849	cell division
A7U47_RS01160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A7U47_RS01175	COG0768	penicillin binding
A7U47_RS01180	COG4839	cell division protein FtsL
A7U47_RS01205	COG1011	Hydrolase
A7U47_RS01240	COG1288	antiporter activity
A7U47_RS01355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A7U47_RS01360	COG1053	succinate dehydrogenase
A7U47_RS01365	COG2009	succinate dehydrogenase
A7U47_RS01390	COG1796	DNA polymerase
A7U47_RS01390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7U47_RS01425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A7U47_RS01440	COG4509	Sortase family
A7U47_RS01500	COG0742	ribosomal rna small subunit methyltransferase
A7U47_RS01520	COG3679	Belongs to the UPF0342 family
A7U47_RS01555	COG0772	Belongs to the SEDS family
A7U47_RS01565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A7U47_RS01575	COG1217	gtp-binding protein TYPA
A7U47_RS01585	COG0483	inositol monophosphate 1-phosphatase activity
A7U47_RS01610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A7U47_RS01615	COG1177	transmembrane transport
A7U47_RS01620	COG1176	ABC-type spermidine putrescine transport system, permease component I
A7U47_RS01685	COG0569	domain protein
A7U47_RS01690	COG1294	oxidase, subunit
A7U47_RS01695	COG1271	oxidase subunit
A7U47_RS01720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A7U47_RS01745	COG4721	ABC-type cobalt transport system, permease component
A7U47_RS01750	COG4172	Belongs to the ABC transporter superfamily
A7U47_RS01755	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A7U47_RS01795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7U47_RS01810	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A7U47_RS01855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7U47_RS01860	COG1316	TRANSCRIPTIONal
A7U47_RS01890	COG3594	Acyltransferase
A7U47_RS01895	COG0436	Aminotransferase
A7U47_RS01920	COG2267	carboxylic ester hydrolase activity
A7U47_RS01930	COG1169	isochorismate synthase
A7U47_RS01940	COG1575	Belongs to the MenA family. Type 1 subfamily
A7U47_RS01945	COG0456	acetyltransferase
A7U47_RS01950	COG2314	TM2 domain
A7U47_RS01960	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A7U47_RS02020	COG4873	Protein conserved in bacteria
A7U47_RS02035	COG4903	ComK protein
A7U47_RS02050	COG0737	Belongs to the 5'-nucleotidase family
A7U47_RS02055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7U47_RS02065	COG0861	Integral membrane protein TerC family
A7U47_RS02105	COG1115	amino acid carrier protein
A7U47_RS02110	COG0628	permease
A7U47_RS02120	COG0475	glutathione-regulated potassium exporter activity
A7U47_RS02120	COG0569	domain protein
A7U47_RS02125	COG2239	Acts as a magnesium transporter
A7U47_RS02130	COG0564	pseudouridine synthase activity
A7U47_RS02140	COG2357	RelA SpoT domain protein
A7U47_RS02155	COG2346	COG2346, Truncated hemoglobins
A7U47_RS02165	COG1164	Oligoendopeptidase f
A7U47_RS02195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U47_RS02200	COG0601	transmembrane transport
A7U47_RS02205	COG4608	Belongs to the ABC transporter superfamily
A7U47_RS02210	COG0444	Belongs to the ABC transporter superfamily
A7U47_RS02215	COG0747	negative chemotaxis
A7U47_RS02220	COG4166	transmembrane transport
A7U47_RS02225	COG4608	Belongs to the ABC transporter superfamily
A7U47_RS02230	COG0444	Belongs to the ABC transporter superfamily
A7U47_RS02235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U47_RS02240	COG0601	transmembrane transport
A7U47_RS02270	COG1881	PFAM PEBP family protein
A7U47_RS02285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7U47_RS02310	COG0561	phosphatase activity
A7U47_RS02350	COG0398	Pfam SNARE associated Golgi protein
A7U47_RS02370	COG0584	glycerophosphoryl diester phosphodiesterase
A7U47_RS02390	COG1902	pentaerythritol trinitrate reductase activity
A7U47_RS02395	COG1098	S1 RNA binding domain
A7U47_RS02450	COG2050	protein possibly involved in aromatic compounds catabolism
A7U47_RS02455	COG2056	Na+-H+ antiporter family
A7U47_RS02460	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A7U47_RS02470	COG0316	Belongs to the HesB IscA family
A7U47_RS02480	COG1252	NADH dehydrogenase
A7U47_RS02485	COG4837	Protein of unknown function (DUF1462)
A7U47_RS02490	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A7U47_RS02495	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A7U47_RS02505	COG1696	Membrane protein involved in D-alanine export
A7U47_RS02535	COG2445	Protein of unknown function DUF86
A7U47_RS02545	COG4470	Protein conserved in bacteria
A7U47_RS02560	COG0730	response to heat
A7U47_RS02565	COG1801	Protein of unknown function DUF72
A7U47_RS02580	COG1253	flavin adenine dinucleotide binding
A7U47_RS02605	COG0822	iron-sulfur transferase activity
A7U47_RS02615	COG0719	Fe-S assembly protein
A7U47_RS02620	COG0396	ATPase activity
A7U47_RS02735	COG0582	viral genome integration into host DNA
A7U47_RS02740	COG1464	Belongs to the NlpA lipoprotein family
A7U47_RS02745	COG2011	ABC-type metal ion transport system permease component
A7U47_RS02760	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A7U47_RS02770	COG3878	Protein conserved in bacteria
A7U47_RS02785	COG1393	Belongs to the ArsC family
A7U47_RS02790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7U47_RS02815	COG1279	arginine transmembrane transporter activity
A7U47_RS02820	COG0406	alpha-ribazole phosphatase activity
A7U47_RS02860	COG1278	Cold shock
A7U47_RS02935	COG0557	exoribonuclease II activity
A7U47_RS02940	COG1647	Serine aminopeptidase, S33
A7U47_RS02945	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A7U47_RS03010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A7U47_RS03070	COG1388	LysM domain
A7U47_RS03070	COG3942	CHAP domain
A7U47_RS03100	COG1040	competence protein
A7U47_RS03105	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A7U47_RS03115	COG1739	Uncharacterized protein family UPF0029
A7U47_RS03120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7U47_RS03175	COG4607	ABC-type enterochelin transport system periplasmic component
A7U47_RS03180	COG4604	ABC transporter, ATP-binding protein
A7U47_RS03185	COG4605	iron ion homeostasis
A7U47_RS03190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U47_RS03205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7U47_RS03210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7U47_RS03240	COG3104	oligopeptide transport
A7U47_RS03270	COG1174	glycine betaine transport
A7U47_RS03275	COG0517	IMP dehydrogenase activity
A7U47_RS03275	COG1125	glycine betaine transport
A7U47_RS03280	COG0514	ATP-dependent DNA helicase (RecQ)
A7U47_RS03285	COG0488	(ABC) transporter
A7U47_RS03315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7U47_RS03320	COG0512	Glutamine amidotransferase of anthranilate synthase
A7U47_RS03320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A7U47_RS03330	COG0720	synthase
A7U47_RS03365	COG0463	Glycosyl transferase, family 2
A7U47_RS03370	COG0656	L-ascorbic acid biosynthetic process
A7U47_RS03375	COG1253	flavin adenine dinucleotide binding
A7U47_RS03380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A7U47_RS03385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U47_RS03385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U47_RS03385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U47_RS03390	COG1105	Belongs to the carbohydrate kinase PfkB family
A7U47_RS03395	COG1349	DNA-binding transcription factor activity
A7U47_RS03400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A7U47_RS03430	COG0415	Belongs to the DNA photolyase family
A7U47_RS03435	COG0471	metal ion transport
A7U47_RS03445	COG4989	oxidoreductase activity
A7U47_RS03450	COG0523	cobalamin synthesis protein
A7U47_RS03460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A7U47_RS03465	COG4988	ABC transporter
A7U47_RS03485	COG1611	Belongs to the LOG family
A7U47_RS03515	COG2839	Protein conserved in bacteria
A7U47_RS03520	COG2814	Major facilitator Superfamily
A7U47_RS03530	COG0583	DNA-binding transcription factor activity
A7U47_RS03560	COG1917	Cupin 2, conserved barrel domain protein
A7U47_RS03560	COG4977	sequence-specific DNA binding
A7U47_RS03570	COG1388	LysM domain
A7U47_RS03570	COG3942	CHAP domain
A7U47_RS03575	COG0306	phosphate transporter
A7U47_RS03580	COG1392	Phosphate transport regulator
A7U47_RS03585	COG0577	efflux transmembrane transporter activity
A7U47_RS03590	COG1136	(ABC) transporter
A7U47_RS03605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7U47_RS03630	COG3949	Membrane
A7U47_RS03640	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
A7U47_RS03650	COG2376	Dihydroxyacetone kinase
A7U47_RS03655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U47_RS03660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U47_RS03665	COG1120	ATPase activity
A7U47_RS03670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7U47_RS03680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7U47_RS03685	COG1132	(ABC) transporter
A7U47_RS03690	COG1686	Belongs to the peptidase S11 family
A7U47_RS03695	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A7U47_RS03700	COG1216	Glycosyl transferase, family 2
A7U47_RS03705	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U47_RS03710	COG1682	transport, permease protein
A7U47_RS03720	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
A7U47_RS03730	COG1321	iron dependent repressor
A7U47_RS03735	COG1121	(ABC) transporter
A7U47_RS03740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7U47_RS03745	COG0803	Belongs to the bacterial solute-binding protein 9 family
A7U47_RS03790	COG4974	Belongs to the 'phage' integrase family
A7U47_RS03825	COG2946	Replication initiation factor
A7U47_RS03845	COG0433	COG0433 Predicted ATPase
A7U47_RS03850	COG1674	ftsk spoiiie
A7U47_RS03880	COG2826	transposase and inactivated derivatives, IS30 family
A7U47_RS03920	COG4139	cobalamin transport
A7U47_RS03925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7U47_RS03965	COG1078	dGTPase activity
A7U47_RS03975	COG0655	NAD(P)H dehydrogenase (quinone) activity
A7U47_RS03980	COG0667	Aldo Keto reductase
A7U47_RS04070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7U47_RS04090	COG0083	homoserine kinase activity
A7U47_RS04095	COG0095	Lipoate-protein ligase
A7U47_RS04210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7U47_RS04255	COG0561	phosphatase activity
A7U47_RS04265	COG1428	Deoxynucleoside kinase
A7U47_RS04270	COG1428	Deoxynucleoside kinase
A7U47_RS04275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A7U47_RS04310	COG1473	amidohydrolase
A7U47_RS04350	COG2813	Specifically methylates the guanine in position
A7U47_RS04410	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A7U47_RS04435	COG4956	integral membrane protein (PIN domain superfamily)
A7U47_RS04440	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A7U47_RS04455	COG3880	PFAM UvrB UvrC protein
A7U47_RS04465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7U47_RS04480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7U47_RS04560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A7U47_RS04585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7U47_RS04600	COG1098	S1 RNA binding domain
A7U47_RS04610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A7U47_RS04615	COG3956	TIGRFAM MazG family protein
A7U47_RS04620	COG2244	polysaccharide biosynthetic process
A7U47_RS04665	COG0251	oxidation-reduction process
A7U47_RS04670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7U47_RS04680	COG4466	Protein conserved in bacteria
A7U47_RS04690	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A7U47_RS04695	COG0084	hydrolase, TatD family'
A7U47_RS04705	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A7U47_RS04715	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A7U47_RS04725	COG1774	PSP1 C-terminal conserved region
A7U47_RS04730	COG0470	DNA polymerase III
A7U47_RS04735	COG3870	Protein conserved in bacteria
A7U47_RS04745	COG1982	Orn Lys Arg decarboxylase major
A7U47_RS04785	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A7U47_RS04805	COG2188	Transcriptional regulator
A7U47_RS04810	COG0366	Alpha amylase catalytic
A7U47_RS04815	COG1263	PTS System
A7U47_RS04815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U47_RS04825	COG0493	'glutamate synthase
A7U47_RS04830	COG0067	glutamate synthase
A7U47_RS04830	COG0069	glutamate synthase activity
A7U47_RS04830	COG0070	glutamate synthase
A7U47_RS04835	COG0583	DNA-binding transcription factor activity
A7U47_RS04870	COG1464	Belongs to the NlpA lipoprotein family
A7U47_RS04875	COG2011	ABC-type metal ion transport system permease component
A7U47_RS04885	COG0626	cystathionine gamma-synthase activity
A7U47_RS04890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7U47_RS04895	COG0733	neurotransmitter:sodium symporter activity
A7U47_RS04905	COG1647	Serine aminopeptidase, S33
A7U47_RS04920	COG5609	conserved protein (DUF2294)
A7U47_RS04930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7U47_RS04955	COG0523	cobalamin synthesis protein
A7U47_RS05120	COG3759	membrane
A7U47_RS05160	COG2233	PERMEase
A7U47_RS05195	COG1823	symporter activity
A7U47_RS05210	COG3634	alkyl hydroperoxide reductase activity
A7U47_RS05270	COG4974	Belongs to the 'phage' integrase family
A7U47_RS05305	COG0012	GTP binding
A7U47_RS05310	COG4481	Protein conserved in bacteria
A7U47_RS05315	COG0668	transmembrane transport
A7U47_RS05320	COG1475	DNA binding
A7U47_RS05330	COG0626	cystathionine gamma-synthase activity
A7U47_RS05335	COG0626	cystathionine gamma-synthase activity
A7U47_RS05340	COG0646	methionine synthase
A7U47_RS05340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A7U47_RS05370	COG1131	(ABC) transporter
A7U47_RS05380	COG1476	TRANSCRIPTIONal
A7U47_RS05390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A7U47_RS05395	COG0805	protein transport
A7U47_RS05400	COG0672	)-iron permease
A7U47_RS05415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7U47_RS05430	COG0431	NADPH-dependent FMN reductase
A7U47_RS05435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7U47_RS05440	COG0346	lactoylglutathione lyase activity
A7U47_RS05445	COG2271	Major facilitator Superfamily
A7U47_RS05470	COG3711	transcriptional antiterminator
A7U47_RS05475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U47_RS05485	COG3037	sugar-specific permease SgaT UlaA
A7U47_RS05515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7U47_RS05540	COG3314	Sporulation integral membrane protein YlbJ
A7U47_RS05565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7U47_RS05570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7U47_RS05600	COG0577	efflux transmembrane transporter activity
A7U47_RS05610	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A7U47_RS05620	COG1114	Component of the transport system for branched-chain amino acids
A7U47_RS05770	COG1388	LysM domain
A7U47_RS05770	COG3942	CHAP domain
A7U47_RS05800	COG1131	(ABC) transporter
A7U47_RS05860	COG2226	methyltransferase
A7U47_RS05870	COG2723	6-phospho-beta-galactosidase activity
A7U47_RS05875	COG2190	(PTS) system
A7U47_RS05875	COG1263	PTS System
A7U47_RS05875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U47_RS05885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7U47_RS05920	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U47_RS05925	COG1063	alcohol dehydrogenase
A7U47_RS05935	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U47_RS05940	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7U47_RS05945	COG1063	alcohol dehydrogenase
A7U47_RS05955	COG1063	alcohol dehydrogenase
A7U47_RS05965	COG1063	alcohol dehydrogenase
A7U47_RS05970	COG3775	system Galactitol-specific IIC component
A7U47_RS05975	COG3414	Phosphotransferase system galactitol-specific IIB component
A7U47_RS05995	COG1957	nucleoside hydrolase
A7U47_RS06000	COG2190	(PTS) system
A7U47_RS06000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U47_RS06000	COG1263	PTS System
A7U47_RS06035	COG3189	MarR family transcriptional regulator
A7U47_RS06040	COG0747	negative chemotaxis
A7U47_RS06055	COG0318	PFAM AMP-dependent synthetase and ligase
A7U47_RS06060	COG1960	acyl-CoA dehydrogenase activity
A7U47_RS06070	COG0183	Belongs to the thiolase family
A7U47_RS06130	COG1755	Isoprenylcysteine carboxyl methyltransferase
A7U47_RS06140	COG0673	inositol 2-dehydrogenase activity
A7U47_RS06145	COG0673	inositol 2-dehydrogenase activity
A7U47_RS06150	COG3833	ABC-type maltose transport systems, permease component
A7U47_RS06155	COG1175	transmembrane transport
A7U47_RS06165	COG3842	ATPase activity
A7U47_RS06185	COG0405	Gamma-glutamyltransferase
A7U47_RS06195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U47_RS06200	COG0601	transmembrane transport
A7U47_RS06235	COG1737	Transcriptional regulator
A7U47_RS06265	COG3961	Belongs to the TPP enzyme family
A7U47_RS06270	COG1335	isochorismatase
A7U47_RS06275	COG1114	Component of the transport system for branched-chain amino acids
A7U47_RS06325	COG5609	conserved protein (DUF2294)
A7U47_RS06330	COG1960	acyl-CoA dehydrogenase activity
A7U47_RS06335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7U47_RS06370	COG2832	Protein of unknown function (DUF454)
A7U47_RS06380	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7U47_RS06385	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A7U47_RS06395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7U47_RS06425	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7U47_RS06435	COG1086	Polysaccharide biosynthesis protein
A7U47_RS06460	COG1454	alcohol dehydrogenase
A7U47_RS06460	COG1012	belongs to the aldehyde dehydrogenase family
A7U47_RS06490	COG0737	Belongs to the 5'-nucleotidase family
A7U47_RS06510	COG3639	organic phosphonate transmembrane transporter activity
A7U47_RS06530	COG2814	Major facilitator Superfamily
A7U47_RS06535	COG0813	purine-nucleoside phosphorylase activity
A7U47_RS06570	COG0438	transferase activity, transferring glycosyl groups
A7U47_RS06575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7U47_RS06580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7U47_RS06610	COG1475	DNA binding
A7U47_RS06615	COG0019	diaminopimelate decarboxylase activity
A7U47_RS06625	COG4264	IucA IucC family
A7U47_RS06630	COG4264	IucA IucC family
A7U47_RS06635	COG2814	Major facilitator Superfamily
A7U47_RS06640	COG4264	IucA IucC family
A7U47_RS06645	COG2423	ornithine cyclodeaminase activity
A7U47_RS06655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7U47_RS06660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U47_RS06665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U47_RS06685	COG1620	l-lactate permease
A7U47_RS06700	COG0697	spore germination
A7U47_RS06705	COG4716	Myosin-crossreactive antigen
A7U47_RS06710	COG1283	sodium-dependent phosphate transmembrane transporter activity
A7U47_RS06720	COG1473	amidohydrolase
A7U47_RS06750	COG0823	Involved in the tonB-independent uptake of proteins
A7U47_RS06770	COG0583	DNA-binding transcription factor activity
A7U47_RS06785	COG0655	NAD(P)H dehydrogenase (quinone) activity
A7U47_RS06830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7U47_RS06835	COG2210	Belongs to the sulfur carrier protein TusA family
A7U47_RS06840	COG1937	Protein conserved in bacteria
A7U47_RS06845	COG0730	response to heat
A7U47_RS06875	COG1388	LysM domain
A7U47_RS06885	COG1124	(ABC) transporter
A7U47_RS06890	COG4172	Belongs to the ABC transporter superfamily
A7U47_RS06895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U47_RS06945	COG2235	arginine
A7U47_RS06955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7U47_RS06960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A7U47_RS07010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7U47_RS07020	COG2801	Transposase and inactivated derivatives
A7U47_RS07140	COG2030	dehydratase
A7U47_RS07145	COG0584	glycerophosphoryl diester phosphodiesterase
A7U47_RS07155	COG3425	synthase
A7U47_RS07175	COG0737	Belongs to the 5'-nucleotidase family
A7U47_RS07180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A7U47_RS07190	COG4863	YycH protein
A7U47_RS07225	COG0305	Participates in initiation and elongation during chromosome replication
A7U47_RS07235	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A7U47_RS07245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A7U47_RS07275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A7U47_RS07295	COG2501	S4 domain
A7U47_RS07335	COG1475	DNA binding
A7U47_RS07360	COG1278	Cold shock
A7U47_RS07390	COG0577	efflux transmembrane transporter activity
A7U47_RS07395	COG1136	(ABC) transporter
A7U47_RS07410	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
A7U47_RS07420	COG2962	Rard protein
A7U47_RS07425	COG0471	metal ion transport
A7U47_RS07510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7U47_RS07545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
A7U47_RS07600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7U47_RS07620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7U47_RS07640	COG1073	alpha beta
A7U47_RS07655	COG0438	transferase activity, transferring glycosyl groups
A7U47_RS07670	COG3433	isochorismatase activity
A7U47_RS07670	COG1535	isochorismatase
A7U47_RS07675	COG3942	CHAP domain
A7U47_RS07675	COG1705	Flagellar rod assembly protein muramidase FlgJ
A7U47_RS07685	COG1482	cell wall glycoprotein biosynthetic process
A7U47_RS07690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U47_RS07690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7U47_RS07690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U47_RS07695	COG3711	transcriptional antiterminator
A7U47_RS07695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7U47_RS07715	COG1438	arginine binding
A7U47_RS07760	COG1846	Transcriptional regulator
A7U47_RS07770	COG1785	Belongs to the alkaline phosphatase family
A7U47_RS07780	COG0745	RESPONSE REGULATOR receiver
A7U47_RS07785	COG2205	protein histidine kinase activity
A7U47_RS07790	COG1136	(ABC) transporter
A7U47_RS07815	COG0386	Belongs to the glutathione peroxidase family
A7U47_RS07825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A7U47_RS07840	COG2851	Citrate transporter
A7U47_RS07865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7U47_RS07875	COG1510	regulation of RNA biosynthetic process
A7U47_RS07885	COG1012	belongs to the aldehyde dehydrogenase family
A7U47_RS07905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7U47_RS07935	COG0531	amino acid
A7U47_RS07950	COG3527	Alpha-acetolactate decarboxylase
A7U47_RS07955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7U47_RS08005	COG0167	dihydroorotate dehydrogenase activity
A7U47_RS08010	COG3001	Fructosamine kinase
A7U47_RS08120	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A7U47_RS08120	COG2755	lipolytic protein G-D-S-L family
A7U47_RS08125	COG3942	CHAP domain
A7U47_RS08155	COG0436	Aminotransferase
A7U47_RS08200	COG2409	Drug exporters of the RND superfamily
A7U47_RS08220	COG0542	response to heat
A7U47_RS08225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7U47_RS08230	COG3425	synthase
A7U47_RS08255	COG3942	CHAP domain
A7U47_RS08265	COG0583	DNA-binding transcription factor activity
A7U47_RS08280	COG0028	Belongs to the TPP enzyme family
A7U47_RS08300	COG0657	acetylesterase activity
A7U47_RS08305	COG0697	spore germination
A7U47_RS08320	COG1760	l-serine dehydratase
A7U47_RS08325	COG1760	l-serine dehydratase
A7U47_RS08345	COG3764	Sortase (surface protein transpeptidase)
A7U47_RS08355	COG1131	(ABC) transporter
A7U47_RS08360	COG0561	phosphatase activity
A7U47_RS08375	COG2514	catechol 2,3-dioxygenase activity
A7U47_RS08385	COG1846	Transcriptional regulator
A7U47_RS08390	COG0346	lactoylglutathione lyase activity
A7U47_RS08395	COG0400	carboxylic ester hydrolase activity
A7U47_RS08415	COG1131	(ABC) transporter
A7U47_RS08430	COG1846	Transcriptional regulator
A7U47_RS08435	COG2814	Major facilitator Superfamily
A7U47_RS08445	COG0586	Pfam SNARE associated Golgi protein
A7U47_RS08450	COG2271	Major facilitator Superfamily
A7U47_RS08460	COG4876	unkown
A7U47_RS08465	COG2357	RelA SpoT domain protein
A7U47_RS08470	COG0789	Transcriptional regulator
A7U47_RS08475	COG1802	Transcriptional regulator
A7U47_RS08480	COG1070	Carbohydrate kinase
A7U47_RS08515	COG1846	Transcriptional regulator
A7U47_RS08520	COG1846	Transcriptional regulator
A7U47_RS08560	COG0494	nUDIX hydrolase
A7U47_RS08650	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7U47_RS08655	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
A7U47_RS08685	COG0747	negative chemotaxis
A7U47_RS08690	COG0601	transmembrane transport
A7U47_RS08695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7U47_RS08700	COG0444	Belongs to the ABC transporter superfamily
A7U47_RS08705	COG1124	(ABC) transporter
A7U47_RS08720	COG0069	glutamate synthase activity
A7U47_RS08725	COG4808	Protein conserved in bacteria
A7U47_RS08745	COG1363	Peptidase, m42
A7U47_RS08750	COG4619	ABC transporter
A7U47_RS08755	COG0390	transport system, permease component
A7U47_RS08760	COG2814	Major facilitator Superfamily
A7U47_RS08765	COG2272	Belongs to the type-B carboxylesterase lipase family
A7U47_RS08770	COG0531	amino acid
A7U47_RS08780	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
A7U47_RS08800	COG1174	glycine betaine transport
A7U47_RS08810	COG1174	glycine betaine transport
A7U47_RS08820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7U47_RS08845	COG0531	amino acid
A7U47_RS08860	COG1113	amino acid transport
A7U47_RS08880	COG2814	Major facilitator Superfamily
A7U47_RS08890	COG1929	Belongs to the glycerate kinase type-1 family
A7U47_RS08910	COG1132	(ABC) transporter
A7U47_RS08910	COG2375	cellular response to nickel ion
A7U47_RS08915	COG1132	(ABC) transporter
A7U47_RS08930	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A7U47_RS08935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7U47_RS08945	COG0156	8-amino-7-oxononanoate synthase activity
A7U47_RS08995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7U47_RS09015	COG2814	Major facilitator Superfamily
A7U47_RS09020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7U47_RS09025	COG0765	amino acid transport
A7U47_RS09030	COG1126	abc transporter atp-binding protein
A7U47_RS09070	COG0803	Belongs to the bacterial solute-binding protein 9 family
A7U47_RS09070	COG3443	Belongs to the bacterial solute-binding protein 9 family
A7U47_RS09085	COG2116	formate transmembrane transporter activity
A7U47_RS09090	COG0454	-acetyltransferase
A7U47_RS09100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7U47_RS09105	COG2146	nitrite reductase [NAD(P)H] activity
A7U47_RS09115	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A7U47_RS09120	COG1140	nitrate reductase beta subunit
A7U47_RS09130	COG2181	nitrate reductase activity
A7U47_RS09150	COG0789	Transcriptional regulator
A7U47_RS09190	COG3871	stress protein (general stress protein 26)
A7U47_RS09205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U47_RS09205	COG1263	PTS System
A7U47_RS09220	COG1511	domain protein
A7U47_RS09245	COG0456	acetyltransferase
A7U47_RS09250	COG0604	alcohol dehydrogenase
A7U47_RS09270	COG1620	l-lactate permease
A7U47_RS09340	COG2814	Major facilitator Superfamily
A7U47_RS09350	COG1566	PFAM secretion protein HlyD family protein
A7U47_RS09355	COG2814	Major facilitator Superfamily
A7U47_RS09365	COG0657	acetylesterase activity
A7U47_RS09380	COG0598	Magnesium transport protein CorA
A7U47_RS09390	COG0786	glutamate:sodium symporter activity
A7U47_RS09405	COG3152	Membrane
A7U47_RS09410	COG4152	abc transporter atp-binding protein
A7U47_RS09415	COG1668	transmembrane transport
A7U47_RS09435	COG2258	MOSC domain
A7U47_RS09460	COG0583	DNA-binding transcription factor activity
A7U47_RS09475	COG1473	amidohydrolase
A7U47_RS09480	COG1028	Short-chain dehydrogenase reductase Sdr
A7U47_RS09500	COG1737	Transcriptional regulator
A7U47_RS09505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U47_RS09505	COG1263	PTS System
A7U47_RS09515	COG0385	Bile acid
A7U47_RS09520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7U47_RS09540	COG1113	amino acid transport
A7U47_RS09615	COG3942	CHAP domain
A7U47_RS09630	COG1757	Na H antiporter
A7U47_RS09640	COG3942	CHAP domain
A7U47_RS09705	COG4413	Urea transporter
A7U47_RS09710	COG1960	acyl-CoA dehydrogenase activity
A7U47_RS09725	COG1268	BioY protein
A7U47_RS09740	COG0725	ABC transporter, periplasmic molybdate-binding protein
A7U47_RS09745	COG4149	molybdate abc transporter
A7U47_RS09750	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A7U47_RS09755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7U47_RS09775	COG1763	Mo-molybdopterin cofactor biosynthetic process
A7U47_RS09850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A7U47_RS09895	COG2252	PERMEase
A7U47_RS10010	COG0201	protein transport
A7U47_RS10095	COG0542	response to heat
A7U47_RS10115	COG0028	Belongs to the TPP enzyme family
A7U47_RS10120	COG3527	Alpha-acetolactate decarboxylase
A7U47_RS10140	COG5492	domain, Protein
A7U47_RS10150	COG0789	Transcriptional regulator
A7U47_RS10155	COG0656	L-ascorbic acid biosynthetic process
A7U47_RS10175	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A7U47_RS10225	COG2130	NADP-dependent
A7U47_RS10235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7U47_RS10265	COG2814	Major facilitator Superfamily
A7U47_RS10270	COG4264	IucA IucC family
A7U47_RS10275	COG3457	Alanine racemase
A7U47_RS10285	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A7U47_RS10290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U47_RS10295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7U47_RS10300	COG3314	Sporulation integral membrane protein YlbJ
A7U47_RS10310	COG1988	membrane-bound metal-dependent
A7U47_RS10320	COG1272	protein, Hemolysin III
A7U47_RS10335	COG2814	Major facilitator Superfamily
A7U47_RS10340	COG0489	protein tyrosine kinase activity
A7U47_RS10415	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A7U47_RS10445	COG3711	transcriptional antiterminator
A7U47_RS10460	COG1119	ATPase activity
A7U47_RS10465	COG0561	phosphatase activity
A7U47_RS10500	COG0640	Transcriptional regulator
A7U47_RS10505	COG0702	epimerase
A7U47_RS10510	COG1482	cell wall glycoprotein biosynthetic process
A7U47_RS10530	COG0783	Belongs to the Dps family
A7U47_RS10535	COG0813	purine-nucleoside phosphorylase activity
A7U47_RS10585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7U47_RS10625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A7U47_RS10650	COG2890	protein-(glutamine-N5) methyltransferase activity
A7U47_RS10655	COG0009	L-threonylcarbamoyladenylate synthase
A7U47_RS10680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7U47_RS10755	COG0629	single-stranded DNA binding
A7U47_RS10805	COG1418	mRNA catabolic process
A7U47_RS10815	COG1937	Protein conserved in bacteria
A7U47_RS10830	COG0772	Belongs to the SEDS family
A7U47_RS10840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A7U47_RS10850	COG0745	RESPONSE REGULATOR receiver
A7U47_RS10855	COG2205	protein histidine kinase activity
A7U47_RS10885	COG3428	Bacterial PH domain
A7U47_RS10920	COG2208	phosphoserine phosphatase activity
A7U47_RS10925	COG1366	Belongs to the anti-sigma-factor antagonist family
A7U47_RS10935	COG1191	sigma factor activity
A7U47_RS10940	COG2183	response to ionizing radiation
A7U47_RS11015	COG0028	Belongs to the TPP enzyme family
A7U47_RS11030	COG0802	atpase or kinase
A7U47_RS11035	COG1214	PFAM Peptidase M22, glycoprotease
A7U47_RS11040	COG0456	acetyltransferase
A7U47_RS11050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A7U47_RS11060	COG0488	(ABC) transporter
A7U47_RS11070	COG2391	methyltransferase activity
A7U47_RS11075	COG0425	Belongs to the sulfur carrier protein TusA family
A7U47_RS11080	COG0004	ammonium transporteR
A7U47_RS11085	COG1609	Transcriptional regulator
A7U47_RS11090	COG1621	beta-fructofuranosidase activity
A7U47_RS11095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7U47_RS11170	COG5484	DNA packaging
A7U47_RS11170	COG3728	DNA packaging
A7U47_RS11190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7U47_RS11195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7U47_RS11200	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7U47_RS11250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A7U47_RS11425	COG0740	serine-type endopeptidase activity
A7U47_RS11475	COG0739	heme binding
A7U47_RS11520	COG1388	LysM domain
A7U47_RS11520	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7U47_RS11535	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7U47_RS11535	COG1388	LysM domain
A7U47_RS11595	COG1725	Transcriptional regulator
A7U47_RS11610	COG1131	(ABC) transporter
A7U47_RS11665	COG1012	belongs to the aldehyde dehydrogenase family
A7U47_RS11680	COG1335	isochorismatase
A7U47_RS11700	COG0077	Prephenate dehydratase
A7U47_RS11710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A7U47_RS11750	COG4496	protein, YerC YecD
A7U47_RS11760	COG0210	DNA helicase
A7U47_RS11770	COG4851	CamS sex pheromone cAM373 precursor
A7U47_RS11900	COG2197	response regulator
A7U47_RS11905	COG1295	ribonuclease BN
A7U47_RS11925	COG2309	aminopeptidase activity
A7U47_RS11930	COG1607	acyl-coa hydrolase
A7U47_RS11935	COG0535	radical SAM domain protein
A7U47_RS11965	COG1134	teichoic acid transport
A7U47_RS11965	COG1388	LysM domain
A7U47_RS11980	COG1988	membrane-bound metal-dependent
A7U47_RS12005	COG4129	membrane
A7U47_RS12015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A7U47_RS12020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7U47_RS12200	COG0765	amino acid transport
A7U47_RS12205	COG1126	abc transporter atp-binding protein
A7U47_RS12210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A7U47_RS12250	COG0564	pseudouridine synthase activity
A7U47_RS12255	COG4585	Histidine kinase
A7U47_RS12255	COG2203	Gaf domain
A7U47_RS12260	COG2197	response regulator
A7U47_RS12290	COG0420	3'-5' exonuclease activity
A7U47_RS12325	COG0537	adenosine 5'-monophosphoramidase activity
A7U47_RS12330	COG1131	(ABC) transporter
A7U47_RS12360	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A7U47_RS12480	COG1131	(ABC) transporter
A7U47_RS12660	COG1506	peptidase
A7U47_RS12685	COG0656	L-ascorbic acid biosynthetic process
A7U47_RS12710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A7U47_RS12740	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7U47_RS12740	COG4193	domain, Protein
A7U47_RS12740	COG3266	domain, Protein
A7U47_RS12765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7U47_RS12765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7U47_RS12800	COG2267	carboxylic ester hydrolase activity
A7U47_RS12815	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A7U47_RS12820	COG1242	4 iron, 4 sulfur cluster binding
A7U47_RS12825	COG2814	Major facilitator Superfamily
A7U47_RS12845	COG2081	HI0933 family
A7U47_RS12850	COG2244	polysaccharide biosynthetic process
A7U47_RS12855	COG1187	pseudouridine synthase activity
A7U47_RS12880	COG0510	thiamine kinase activity
A7U47_RS12890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7U47_RS12900	COG1363	Peptidase, m42
A7U47_RS12905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7U47_RS12915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7U47_RS12920	COG1674	ftsk spoiiie
A7U47_RS12945	COG1605	Chorismate mutase
A7U47_RS12945	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A7U47_RS12965	COG0454	-acetyltransferase
A7U47_RS12970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7U47_RS13000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7U47_RS13005	COG0204	Acyl-transferase
A7U47_RS13010	COG1263	PTS System
A7U47_RS13010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7U47_RS13025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7U47_RS13030	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A7U47_RS13035	COG1764	response to oxidative stress
A7U47_RS13040	COG0584	glycerophosphoryl diester phosphodiesterase
A7U47_RS13060	COG1956	GAF domain-containing protein
A7U47_RS13075	COG1104	cysteine desulfurase activity
A7U47_RS13095	COG0827	DNA restriction-modification system
A7U47_RS13135	COG4109	DRTGG domain
A7U47_RS13145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A7U47_RS13155	COG0281	malic enzyme
A7U47_RS13185	COG1113	amino acid transport
A7U47_RS13190	COG0372	Belongs to the citrate synthase family
A7U47_RS13205	COG0745	RESPONSE REGULATOR receiver
A7U47_RS13210	COG5002	protein histidine kinase activity
A7U47_RS13220	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7U47_RS13220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7U47_RS13250	COG1484	DNA-dependent DNA replication
A7U47_RS13265	COG0833	amino acid
A7U47_RS13290	COG4112	unkown
A7U47_RS13325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A7U47_RS13360	COG2818	Glycosylase
A7U47_RS13370	COG0285	dihydrofolate synthase activity
A7U47_RS13380	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A7U47_RS13425	COG2868	ribosomal protein
A7U47_RS13465	COG1862	Preprotein translocase
A7U47_RS13470	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7U47_RS13470	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7U47_RS13475	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A7U47_RS13475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A7U47_RS13520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A7U47_RS13525	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A7U47_RS13530	COG1959	2 iron, 2 sulfur cluster binding
A7U47_RS13545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7U47_RS13550	COG1104	cysteine desulfurase activity
A7U47_RS13565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A7U47_RS13595	COG0826	peptidase U32
A7U47_RS13600	COG0826	peptidase U32
A7U47_RS13615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A7U47_RS13620	COG1984	allophanate hydrolase subunit 2
A7U47_RS13625	COG0511	ligase activity, forming carbon-carbon bonds
A7U47_RS13630	COG0439	Biotin carboxylase
A7U47_RS13640	COG1914	H( )-stimulated, divalent metal cation uptake system
A7U47_RS13645	COG3177	Filamentation induced by cAMP protein fic
A7U47_RS13665	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A7U47_RS13670	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A7U47_RS13680	COG1534	Rna-binding protein
A7U47_RS13690	COG1713	HD superfamily hydrolase involved in NAD metabolism
A7U47_RS13695	COG0799	negative regulation of ribosome biogenesis
A7U47_RS13700	COG2226	methyltransferase
A7U47_RS13710	COG2131	deaminase
A7U47_RS13715	COG0658	competence protein
A7U47_RS13715	COG2333	competence protein COMEC
A7U47_RS13720	COG1466	dna polymerase III delta subunit
A7U47_RS13740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7U47_RS13770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A7U47_RS13775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7U47_RS13785	COG1030	water channel activity
A7U47_RS13800	COG1702	phosphate starvation-inducible protein PhoH
A7U47_RS13815	COG0295	cytidine deaminase activity
A7U47_RS13835	COG0517	IMP dehydrogenase activity
A7U47_RS13855	COG2384	SAM-dependent methyltransferase
A7U47_RS13865	COG0513	Belongs to the DEAD box helicase family
A7U47_RS13875	COG1121	(ABC) transporter
A7U47_RS13880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7U47_RS13895	COG0768	penicillin binding
A7U47_RS13905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A7U47_RS13915	COG4483	Protein conserved in bacteria
A7U47_RS13920	COG1940	carbohydrate kinase activity
A7U47_RS13925	COG0011	TIGRFAM Protein of
A7U47_RS13930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7U47_RS13935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A7U47_RS13940	COG1459	type II secretion system
A7U47_RS13945	COG4537	Required for transformation and DNA binding
A7U47_RS13990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7U47_RS13995	COG0095	Lipoate-protein ligase
A7U47_RS14010	COG0006	proline dipeptidase activity
A7U47_RS14020	COG0511	ligase activity, forming carbon-carbon bonds
A7U47_RS14025	COG0439	Biotin carboxylase
A7U47_RS14030	COG1302	Protein conserved in bacteria
A7U47_RS14060	COG0497	DNA recombination
A7U47_RS14065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7U47_RS14070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A7U47_RS14075	COG0022	dehydrogenase e1 component
A7U47_RS14080	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7U47_RS14090	COG4129	membrane
A7U47_RS14100	COG2195	Cleaves the N-terminal amino acid of tripeptides
A7U47_RS14120	COG1609	Transcriptional regulator
A7U47_RS14125	COG0366	Alpha amylase catalytic
A7U47_RS14135	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A7U47_RS14150	COG4221	oxidoreductase activity
A7U47_RS14160	COG0667	Aldo Keto reductase
A7U47_RS14165	COG0494	nUDIX hydrolase
A7U47_RS14170	COG0735	belongs to the Fur family
A7U47_RS14195	COG1187	pseudouridine synthase activity
A7U47_RS14200	COG0745	RESPONSE REGULATOR receiver
A7U47_RS14205	COG5002	protein histidine kinase activity
A7U47_RS14225	COG0582	viral genome integration into host DNA
A7U47_RS14485	COG3953	SLT domain
A7U47_RS14485	COG5280	Phage tail tape measure protein TP901
A7U47_RS14535	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7U47_RS14535	COG1388	LysM domain
A7U47_RS14585	COG1141	Ferredoxin
A7U47_RS14595	COG0514	ATP-dependent DNA helicase (RecQ)
A7U47_RS14610	COG0492	ferredoxin-NADP+ reductase activity
A7U47_RS14675	COG0142	geranyltranstransferase activity
A7U47_RS14715	COG4347	Protein of unknown function (DUF1405)
A7U47_RS14720	COG2738	Putative neutral zinc metallopeptidase
A7U47_RS14725	COG1694	Mazg nucleotide pyrophosphohydrolase
A7U47_RS14730	COG0438	transferase activity, transferring glycosyl groups
A7U47_RS14755	COG3935	DnaD domain protein
A7U47_RS14760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A7U47_RS14770	COG4499	WXG100 protein secretion system (Wss), protein YukC
A7U47_RS14770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7U47_RS14810	COG0116	Belongs to the methyltransferase superfamily
A7U47_RS14825	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A7U47_RS14830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7U47_RS14845	COG0531	amino acid
A7U47_RS14870	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A7U47_RS14945	COG0671	phosphoesterase, PA-phosphatase related
A7U47_RS15000	COG4548	von Willebrand factor, type A
A7U47_RS15080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A7U47_RS15085	COG0527	aspartate kinase activity
A7U47_RS15090	COG0488	(ABC) transporter
A7U47_RS15110	COG0573	inorganic phosphate transmembrane transporter activity
A7U47_RS15115	COG0581	inorganic phosphate transmembrane transporter activity
A7U47_RS15125	COG0704	Plays a role in the regulation of phosphate uptake
A7U47_RS15170	COG0561	phosphatase activity
A7U47_RS15210	COG0512	Glutamine amidotransferase of anthranilate synthase
A7U47_RS15215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7U47_RS15220	COG1363	Peptidase, m42
A7U47_RS15230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A7U47_RS15250	COG0392	lysyltransferase activity
A7U47_RS15250	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A7U47_RS15255	COG0628	permease
A7U47_RS15270	COG1115	amino acid carrier protein
A7U47_RS15310	COG0824	Thioesterase
A7U47_RS15350	COG2211	Major facilitator Superfamily