locus-tag	class	description
SAAV_RS00025	COG2501	S4 domain
SAAV_RS00045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SAAV_RS00070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SAAV_RS00080	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SAAV_RS00090	COG0305	Participates in initiation and elongation during chromosome replication
SAAV_RS00120	COG4863	YycH protein
SAAV_RS00130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SAAV_RS00135	COG0737	Belongs to the 5'-nucleotidase family
SAAV_RS00170	COG0730	response to heat
SAAV_RS00175	COG1937	Protein conserved in bacteria
SAAV_RS00180	COG2210	Belongs to the sulfur carrier protein TusA family
SAAV_RS00185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAAV_RS00230	COG0823	Involved in the tonB-independent uptake of proteins
SAAV_RS00250	COG2826	transposase and inactivated derivatives, IS30 family
SAAV_RS00275	COG5644	endopeptidase inhibitor activity
SAAV_RS00280	COG1674	ftsk spoiiie
SAAV_RS00290	COG0433	COG0433 Predicted ATPase
SAAV_RS00310	COG2946	Replication initiation factor
SAAV_RS00355	COG1473	amidohydrolase
SAAV_RS00365	COG1283	sodium-dependent phosphate transmembrane transporter activity
SAAV_RS00370	COG4716	Myosin-crossreactive antigen
SAAV_RS00375	COG0697	spore germination
SAAV_RS00390	COG1620	l-lactate permease
SAAV_RS00410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAAV_RS00415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAAV_RS00420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAAV_RS00430	COG2423	ornithine cyclodeaminase activity
SAAV_RS00435	COG4264	IucA IucC family
SAAV_RS00440	COG2814	Major facilitator Superfamily
SAAV_RS00445	COG4264	IucA IucC family
SAAV_RS00450	COG4264	IucA IucC family
SAAV_RS00460	COG0019	diaminopimelate decarboxylase activity
SAAV_RS00465	COG1475	DNA binding
SAAV_RS00490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAAV_RS00495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAAV_RS00500	COG0438	transferase activity, transferring glycosyl groups
SAAV_RS00535	COG0813	purine-nucleoside phosphorylase activity
SAAV_RS00540	COG2814	Major facilitator Superfamily
SAAV_RS00560	COG3639	organic phosphonate transmembrane transporter activity
SAAV_RS00580	COG0737	Belongs to the 5'-nucleotidase family
SAAV_RS00595	COG1012	belongs to the aldehyde dehydrogenase family
SAAV_RS00595	COG1454	alcohol dehydrogenase
SAAV_RS00620	COG1086	Polysaccharide biosynthesis protein
SAAV_RS00630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAAV_RS00660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAAV_RS00670	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SAAV_RS00675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAAV_RS00685	COG2832	Protein of unknown function (DUF454)
SAAV_RS00725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SAAV_RS00730	COG1960	acyl-CoA dehydrogenase activity
SAAV_RS00735	COG5609	conserved protein (DUF2294)
SAAV_RS00785	COG1114	Component of the transport system for branched-chain amino acids
SAAV_RS00790	COG1335	isochorismatase
SAAV_RS00795	COG3961	Belongs to the TPP enzyme family
SAAV_RS00825	COG1737	Transcriptional regulator
SAAV_RS00850	COG1136	(ABC) transporter
SAAV_RS00855	COG0577	efflux transmembrane transporter activity
SAAV_RS00855	COG1136	(ABC) transporter
SAAV_RS00875	COG1131	(ABC) transporter
SAAV_RS00890	COG0601	transmembrane transport
SAAV_RS00895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAAV_RS00905	COG0405	Gamma-glutamyltransferase
SAAV_RS00925	COG3842	ATPase activity
SAAV_RS00935	COG1175	transmembrane transport
SAAV_RS00940	COG3833	ABC-type maltose transport systems, permease component
SAAV_RS00945	COG0673	inositol 2-dehydrogenase activity
SAAV_RS00950	COG0673	inositol 2-dehydrogenase activity
SAAV_RS00960	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAAV_RS01020	COG0183	Belongs to the thiolase family
SAAV_RS01030	COG1960	acyl-CoA dehydrogenase activity
SAAV_RS01035	COG0318	PFAM AMP-dependent synthetase and ligase
SAAV_RS01050	COG0747	negative chemotaxis
SAAV_RS01055	COG3189	MarR family transcriptional regulator
SAAV_RS01085	COG2190	(PTS) system
SAAV_RS01085	COG1263	PTS System
SAAV_RS01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAAV_RS01090	COG1957	nucleoside hydrolase
SAAV_RS01110	COG3414	Phosphotransferase system galactitol-specific IIB component
SAAV_RS01115	COG3775	system Galactitol-specific IIC component
SAAV_RS01120	COG1063	alcohol dehydrogenase
SAAV_RS01140	COG1063	alcohol dehydrogenase
SAAV_RS01145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAAV_RS01150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAAV_RS01160	COG1063	alcohol dehydrogenase
SAAV_RS01165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAAV_RS01200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAAV_RS01205	COG2190	(PTS) system
SAAV_RS01205	COG1263	PTS System
SAAV_RS01205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAAV_RS01210	COG2723	6-phospho-beta-galactosidase activity
SAAV_RS01220	COG2226	methyltransferase
SAAV_RS01275	COG1131	(ABC) transporter
SAAV_RS01295	COG3942	CHAP domain
SAAV_RS01295	COG1388	LysM domain
SAAV_RS01415	COG1114	Component of the transport system for branched-chain amino acids
SAAV_RS01420	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SAAV_RS01430	COG0577	efflux transmembrane transporter activity
SAAV_RS01455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAAV_RS01460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SAAV_RS01485	COG3314	Sporulation integral membrane protein YlbJ
SAAV_RS01510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAAV_RS01540	COG3037	sugar-specific permease SgaT UlaA
SAAV_RS01550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAAV_RS01555	COG3711	transcriptional antiterminator
SAAV_RS01575	COG2271	Major facilitator Superfamily
SAAV_RS01580	COG0346	lactoylglutathione lyase activity
SAAV_RS01585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAAV_RS01590	COG0431	NADPH-dependent FMN reductase
SAAV_RS01605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAAV_RS01610	COG2822	iron ion transport
SAAV_RS01620	COG0672	)-iron permease
SAAV_RS01625	COG0805	protein transport
SAAV_RS01630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SAAV_RS01640	COG1476	TRANSCRIPTIONal
SAAV_RS01650	COG1131	(ABC) transporter
SAAV_RS01685	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SAAV_RS01685	COG0646	methionine synthase
SAAV_RS01690	COG0626	cystathionine gamma-synthase activity
SAAV_RS01695	COG0626	cystathionine gamma-synthase activity
SAAV_RS01700	COG1475	DNA binding
SAAV_RS01705	COG0668	transmembrane transport
SAAV_RS01710	COG4481	Protein conserved in bacteria
SAAV_RS01715	COG0012	GTP binding
SAAV_RS01815	COG1823	symporter activity
SAAV_RS01845	COG2233	PERMEase
SAAV_RS01880	COG3759	membrane
SAAV_RS02050	COG0523	cobalamin synthesis protein
SAAV_RS02060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SAAV_RS02070	COG5609	conserved protein (DUF2294)
SAAV_RS02085	COG1647	Serine aminopeptidase, S33
SAAV_RS02090	COG0733	neurotransmitter:sodium symporter activity
SAAV_RS02095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAAV_RS02100	COG0626	cystathionine gamma-synthase activity
SAAV_RS02110	COG2011	ABC-type metal ion transport system permease component
SAAV_RS02115	COG1464	Belongs to the NlpA lipoprotein family
SAAV_RS02150	COG0583	DNA-binding transcription factor activity
SAAV_RS02155	COG0069	glutamate synthase activity
SAAV_RS02155	COG0067	glutamate synthase
SAAV_RS02155	COG0070	glutamate synthase
SAAV_RS02160	COG0493	'glutamate synthase
SAAV_RS02170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAAV_RS02170	COG1263	PTS System
SAAV_RS02175	COG0366	Alpha amylase catalytic
SAAV_RS02180	COG2188	Transcriptional regulator
SAAV_RS02195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAAV_RS02230	COG1982	Orn Lys Arg decarboxylase major
SAAV_RS02240	COG3870	Protein conserved in bacteria
SAAV_RS02250	COG0470	DNA polymerase III
SAAV_RS02255	COG1774	PSP1 C-terminal conserved region
SAAV_RS02265	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SAAV_RS02275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SAAV_RS02290	COG0084	hydrolase, TatD family'
SAAV_RS02295	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAAV_RS02305	COG4466	Protein conserved in bacteria
SAAV_RS02315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAAV_RS02320	COG0251	oxidation-reduction process
SAAV_RS02365	COG2244	polysaccharide biosynthetic process
SAAV_RS02370	COG3956	TIGRFAM MazG family protein
SAAV_RS02375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SAAV_RS02385	COG1098	S1 RNA binding domain
SAAV_RS02400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAAV_RS02425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SAAV_RS02505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAAV_RS02520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAAV_RS02530	COG3880	PFAM UvrB UvrC protein
SAAV_RS02550	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SAAV_RS02555	COG4956	integral membrane protein (PIN domain superfamily)
SAAV_RS02575	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SAAV_RS02625	COG2813	Specifically methylates the guanine in position
SAAV_RS02665	COG1473	amidohydrolase
SAAV_RS02695	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SAAV_RS02700	COG1428	Deoxynucleoside kinase
SAAV_RS02705	COG1428	Deoxynucleoside kinase
SAAV_RS02715	COG0561	phosphatase activity
SAAV_RS02755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SAAV_RS02770	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SAAV_RS02860	COG0095	Lipoate-protein ligase
SAAV_RS02865	COG0083	homoserine kinase activity
SAAV_RS02920	COG0667	Aldo Keto reductase
SAAV_RS02925	COG0655	NAD(P)H dehydrogenase (quinone) activity
SAAV_RS02935	COG1078	dGTPase activity
SAAV_RS02970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAAV_RS02975	COG4139	cobalamin transport
SAAV_RS03025	COG4974	Belongs to the 'phage' integrase family
SAAV_RS03070	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAAV_RS03075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAAV_RS03080	COG1121	(ABC) transporter
SAAV_RS03085	COG1321	iron dependent repressor
SAAV_RS03095	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SAAV_RS03105	COG1682	transport, permease protein
SAAV_RS03110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAAV_RS03120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SAAV_RS03125	COG1686	Belongs to the peptidase S11 family
SAAV_RS03130	COG1132	(ABC) transporter
SAAV_RS03135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAAV_RS03145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAAV_RS03150	COG1120	ATPase activity
SAAV_RS03155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAAV_RS03160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAAV_RS03165	COG2376	Dihydroxyacetone kinase
SAAV_RS03175	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SAAV_RS03185	COG3949	Membrane
SAAV_RS03210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAAV_RS03225	COG1136	(ABC) transporter
SAAV_RS03230	COG0577	efflux transmembrane transporter activity
SAAV_RS03235	COG1392	Phosphate transport regulator
SAAV_RS03240	COG0306	phosphate transporter
SAAV_RS03245	COG3942	CHAP domain
SAAV_RS03245	COG1388	LysM domain
SAAV_RS03255	COG1917	Cupin 2, conserved barrel domain protein
SAAV_RS03255	COG4977	sequence-specific DNA binding
SAAV_RS03285	COG0583	DNA-binding transcription factor activity
SAAV_RS03290	COG2814	Major facilitator Superfamily
SAAV_RS03295	COG2839	Protein conserved in bacteria
SAAV_RS03325	COG1611	Belongs to the LOG family
SAAV_RS03345	COG4988	ABC transporter
SAAV_RS03350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAAV_RS03360	COG0523	cobalamin synthesis protein
SAAV_RS03365	COG4989	oxidoreductase activity
SAAV_RS03375	COG0471	metal ion transport
SAAV_RS03380	COG0415	Belongs to the DNA photolyase family
SAAV_RS03410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAAV_RS03415	COG1349	DNA-binding transcription factor activity
SAAV_RS03420	COG1105	Belongs to the carbohydrate kinase PfkB family
SAAV_RS03425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAAV_RS03425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAAV_RS03425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAAV_RS03435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SAAV_RS03440	COG1253	flavin adenine dinucleotide binding
SAAV_RS03445	COG0656	L-ascorbic acid biosynthetic process
SAAV_RS03450	COG0463	Glycosyl transferase, family 2
SAAV_RS03485	COG0720	synthase
SAAV_RS03495	COG0512	Glutamine amidotransferase of anthranilate synthase
SAAV_RS03495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SAAV_RS03500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAAV_RS03535	COG0488	(ABC) transporter
SAAV_RS03540	COG0514	ATP-dependent DNA helicase (RecQ)
SAAV_RS03545	COG0517	IMP dehydrogenase activity
SAAV_RS03545	COG1125	glycine betaine transport
SAAV_RS03550	COG1174	glycine betaine transport
SAAV_RS03580	COG3104	oligopeptide transport
SAAV_RS03600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAAV_RS03605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAAV_RS03615	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAAV_RS03620	COG4605	iron ion homeostasis
SAAV_RS03625	COG4604	ABC transporter, ATP-binding protein
SAAV_RS03630	COG4607	ABC-type enterochelin transport system periplasmic component
SAAV_RS03685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAAV_RS03690	COG1739	Uncharacterized protein family UPF0029
SAAV_RS03700	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SAAV_RS03705	COG1040	competence protein
SAAV_RS03735	COG1388	LysM domain
SAAV_RS03735	COG3942	CHAP domain
SAAV_RS03790	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SAAV_RS03855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SAAV_RS03860	COG1647	Serine aminopeptidase, S33
SAAV_RS03865	COG0557	exoribonuclease II activity
SAAV_RS03935	COG1278	Cold shock
SAAV_RS03975	COG0406	alpha-ribazole phosphatase activity
SAAV_RS03980	COG1279	arginine transmembrane transporter activity
SAAV_RS04005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAAV_RS04010	COG1393	Belongs to the ArsC family
SAAV_RS04025	COG3878	Protein conserved in bacteria
SAAV_RS04035	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAAV_RS04050	COG2011	ABC-type metal ion transport system permease component
SAAV_RS04055	COG1464	Belongs to the NlpA lipoprotein family
SAAV_RS04060	COG0582	viral genome integration into host DNA
SAAV_RS04150	COG5484	DNA packaging
SAAV_RS04150	COG3728	DNA packaging
SAAV_RS04190	COG0396	ATPase activity
SAAV_RS04195	COG0719	Fe-S assembly protein
SAAV_RS04205	COG0822	iron-sulfur transferase activity
SAAV_RS04320	COG1484	DNA-dependent DNA replication
SAAV_RS04360	COG0756	dUTP diphosphatase activity
SAAV_RS04430	COG4695	Portal protein
SAAV_RS04485	COG0739	heme binding
SAAV_RS04530	COG0860	N-Acetylmuramoyl-L-alanine amidase
SAAV_RS04530	COG1388	LysM domain
SAAV_RS04565	COG1253	flavin adenine dinucleotide binding
SAAV_RS04580	COG1801	Protein of unknown function DUF72
SAAV_RS04585	COG0730	response to heat
SAAV_RS04600	COG4470	Protein conserved in bacteria
SAAV_RS04610	COG2445	Protein of unknown function DUF86
SAAV_RS04640	COG1696	Membrane protein involved in D-alanine export
SAAV_RS04650	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SAAV_RS04655	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SAAV_RS04660	COG4837	Protein of unknown function (DUF1462)
SAAV_RS04665	COG1252	NADH dehydrogenase
SAAV_RS04675	COG0316	Belongs to the HesB IscA family
SAAV_RS04685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SAAV_RS04690	COG2056	Na+-H+ antiporter family
SAAV_RS04695	COG2050	protein possibly involved in aromatic compounds catabolism
SAAV_RS04750	COG1098	S1 RNA binding domain
SAAV_RS04755	COG1902	pentaerythritol trinitrate reductase activity
SAAV_RS04770	COG0584	glycerophosphoryl diester phosphodiesterase
SAAV_RS04790	COG0398	Pfam SNARE associated Golgi protein
SAAV_RS04830	COG0561	phosphatase activity
SAAV_RS04870	COG1881	PFAM PEBP family protein
SAAV_RS04900	COG0601	transmembrane transport
SAAV_RS04905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAAV_RS04910	COG0444	Belongs to the ABC transporter superfamily
SAAV_RS04915	COG4608	Belongs to the ABC transporter superfamily
SAAV_RS04920	COG4166	transmembrane transport
SAAV_RS04925	COG0747	negative chemotaxis
SAAV_RS04930	COG0444	Belongs to the ABC transporter superfamily
SAAV_RS04935	COG4608	Belongs to the ABC transporter superfamily
SAAV_RS04940	COG0601	transmembrane transport
SAAV_RS04945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAAV_RS04975	COG1164	Oligoendopeptidase f
SAAV_RS04985	COG2346	COG2346, Truncated hemoglobins
SAAV_RS05000	COG2357	RelA SpoT domain protein
SAAV_RS05010	COG0564	pseudouridine synthase activity
SAAV_RS05015	COG2239	Acts as a magnesium transporter
SAAV_RS05020	COG0475	glutathione-regulated potassium exporter activity
SAAV_RS05020	COG0569	domain protein
SAAV_RS05030	COG0628	permease
SAAV_RS05035	COG1115	amino acid carrier protein
SAAV_RS05075	COG0861	Integral membrane protein TerC family
SAAV_RS05085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAAV_RS05090	COG0737	Belongs to the 5'-nucleotidase family
SAAV_RS05105	COG4903	ComK protein
SAAV_RS05120	COG4873	Protein conserved in bacteria
SAAV_RS05165	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAAV_RS05175	COG2314	TM2 domain
SAAV_RS05180	COG0456	acetyltransferase
SAAV_RS05185	COG1575	Belongs to the MenA family. Type 1 subfamily
SAAV_RS05190	COG1169	isochorismate synthase
SAAV_RS05200	COG2267	carboxylic ester hydrolase activity
SAAV_RS05225	COG0436	Aminotransferase
SAAV_RS05230	COG3594	Acyltransferase
SAAV_RS05260	COG1316	TRANSCRIPTIONal
SAAV_RS05305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SAAV_RS05320	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAAV_RS05360	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SAAV_RS05365	COG4172	Belongs to the ABC transporter superfamily
SAAV_RS05370	COG4721	ABC-type cobalt transport system, permease component
SAAV_RS05395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAAV_RS05415	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SAAV_RS05420	COG1271	oxidase subunit
SAAV_RS05425	COG1294	oxidase, subunit
SAAV_RS05430	COG0569	domain protein
SAAV_RS05495	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAAV_RS05500	COG1177	transmembrane transport
SAAV_RS05505	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SAAV_RS05535	COG0483	inositol monophosphate 1-phosphatase activity
SAAV_RS05545	COG1217	gtp-binding protein TYPA
SAAV_RS05555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SAAV_RS05565	COG0772	Belongs to the SEDS family
SAAV_RS05600	COG3679	Belongs to the UPF0342 family
SAAV_RS05620	COG0742	ribosomal rna small subunit methyltransferase
SAAV_RS05680	COG4509	Sortase family
SAAV_RS05695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAAV_RS05725	COG1796	DNA polymerase
SAAV_RS05725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SAAV_RS05750	COG2009	succinate dehydrogenase
SAAV_RS05755	COG1053	succinate dehydrogenase
SAAV_RS05760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SAAV_RS05885	COG1288	antiporter activity
SAAV_RS05920	COG1011	Hydrolase
SAAV_RS05945	COG4839	cell division protein FtsL
SAAV_RS05950	COG0768	penicillin binding
SAAV_RS05965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SAAV_RS05970	COG0849	cell division
SAAV_RS05985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAAV_RS05995	COG0762	integral membrane protein
SAAV_RS06000	COG2302	S4 RNA-binding domain
SAAV_RS06005	COG3599	regulation of cell shape
SAAV_RS06015	COG2514	catechol 2,3-dioxygenase activity
SAAV_RS06030	COG0564	pseudouridine synthase activity
SAAV_RS06040	COG2233	PERMEase
SAAV_RS06085	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SAAV_RS06100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SAAV_RS06105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SAAV_RS06115	COG2314	TM2 domain
SAAV_RS06130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAAV_RS06130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAAV_RS06140	COG0631	protein serine/threonine phosphatase activity
SAAV_RS06155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SAAV_RS06170	COG1302	Protein conserved in bacteria
SAAV_RS06220	COG1196	nuclear chromosome segregation
SAAV_RS06225	COG0552	protein localization to endoplasmic reticulum
SAAV_RS06235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SAAV_RS06295	COG2348	transferase activity, transferring amino-acyl groups
SAAV_RS06300	COG0758	DNA mediated transformation
SAAV_RS06395	COG0195	Participates in both transcription termination and antitermination
SAAV_RS06400	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SAAV_RS06425	COG0196	riboflavin kinase activity
SAAV_RS06450	COG2188	Transcriptional regulator
SAAV_RS06455	COG0612	Peptidase, M16
SAAV_RS06460	COG0612	Peptidase, M16
SAAV_RS06465	COG0300	oxidoreductase activity
SAAV_RS06485	COG1058	Belongs to the CinA family
SAAV_RS06485	COG1546	Belongs to the CinA family
SAAV_RS06505	COG1692	metallophosphoesterase
SAAV_RS06510	COG0674	pyruvate-flavodoxin oxidoreductase activity
SAAV_RS06510	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SAAV_RS06515	COG1013	pyruvate-flavodoxin oxidoreductase activity
SAAV_RS06550	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SAAV_RS06555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAAV_RS06580	COG1923	regulation of RNA biosynthetic process
SAAV_RS06590	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAAV_RS06595	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SAAV_RS06600	COG0789	Transcriptional regulator
SAAV_RS06680	COG1131	(ABC) transporter
SAAV_RS06695	COG2197	response regulator
SAAV_RS06705	COG1525	nuclease
SAAV_RS06720	COG0527	aspartate kinase activity
SAAV_RS06725	COG0460	homoserine dehydrogenase
SAAV_RS06730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SAAV_RS06755	COG0833	amino acid
SAAV_RS06785	COG2340	Cysteine-rich secretory protein family
SAAV_RS06820	COG4846	Membrane protein involved in cytochrome C biogenesis
SAAV_RS06840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAAV_RS06855	COG0824	Thioesterase
SAAV_RS06885	COG1115	amino acid carrier protein
SAAV_RS06900	COG0628	permease
SAAV_RS06925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SAAV_RS06935	COG1363	Peptidase, m42
SAAV_RS06940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAAV_RS06945	COG0512	Glutamine amidotransferase of anthranilate synthase
SAAV_RS06990	COG0561	phosphatase activity
SAAV_RS07035	COG0704	Plays a role in the regulation of phosphate uptake
SAAV_RS07045	COG0581	inorganic phosphate transmembrane transporter activity
SAAV_RS07050	COG0573	inorganic phosphate transmembrane transporter activity
SAAV_RS07075	COG0488	(ABC) transporter
SAAV_RS07080	COG0527	aspartate kinase activity
SAAV_RS07085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SAAV_RS07165	COG4548	von Willebrand factor, type A
SAAV_RS07170	COG0714	Associated with various cellular activities
SAAV_RS07215	COG0671	phosphoesterase, PA-phosphatase related
SAAV_RS07295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SAAV_RS07325	COG0531	amino acid
SAAV_RS07340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAAV_RS07345	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SAAV_RS07365	COG0116	Belongs to the methyltransferase superfamily
SAAV_RS07395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAAV_RS07395	COG4499	WXG100 protein secretion system (Wss), protein YukC
SAAV_RS07405	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SAAV_RS07410	COG3935	DnaD domain protein
SAAV_RS07435	COG0438	transferase activity, transferring glycosyl groups
SAAV_RS07440	COG1694	Mazg nucleotide pyrophosphohydrolase
SAAV_RS07445	COG2738	Putative neutral zinc metallopeptidase
SAAV_RS07450	COG4347	Protein of unknown function (DUF1405)
SAAV_RS07490	COG0142	geranyltranstransferase activity
SAAV_RS07555	COG0492	ferredoxin-NADP+ reductase activity
SAAV_RS07570	COG0514	ATP-dependent DNA helicase (RecQ)
SAAV_RS07580	COG1141	Ferredoxin
SAAV_RS07630	COG0745	RESPONSE REGULATOR receiver
SAAV_RS07635	COG1187	pseudouridine synthase activity
SAAV_RS07660	COG0735	belongs to the Fur family
SAAV_RS07665	COG0494	nUDIX hydrolase
SAAV_RS07670	COG0667	Aldo Keto reductase
SAAV_RS07680	COG4221	oxidoreductase activity
SAAV_RS07695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SAAV_RS07705	COG0366	Alpha amylase catalytic
SAAV_RS07710	COG1609	Transcriptional regulator
SAAV_RS07735	COG2195	Cleaves the N-terminal amino acid of tripeptides
SAAV_RS07745	COG4129	membrane
SAAV_RS07755	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAAV_RS07760	COG0022	dehydrogenase e1 component
SAAV_RS07765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SAAV_RS07770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAAV_RS07775	COG0497	DNA recombination
SAAV_RS07805	COG1302	Protein conserved in bacteria
SAAV_RS07810	COG0439	Biotin carboxylase
SAAV_RS07815	COG0511	ligase activity, forming carbon-carbon bonds
SAAV_RS07825	COG0006	proline dipeptidase activity
SAAV_RS07840	COG0095	Lipoate-protein ligase
SAAV_RS07845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAAV_RS07890	COG4537	Required for transformation and DNA binding
SAAV_RS07895	COG1459	type II secretion system
SAAV_RS07900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SAAV_RS07905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAAV_RS07910	COG0011	TIGRFAM Protein of
SAAV_RS07915	COG1940	carbohydrate kinase activity
SAAV_RS07920	COG4483	Protein conserved in bacteria
SAAV_RS07930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAAV_RS07940	COG0768	penicillin binding
SAAV_RS07955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAAV_RS07960	COG1121	(ABC) transporter
SAAV_RS07970	COG0513	Belongs to the DEAD box helicase family
SAAV_RS07980	COG2384	SAM-dependent methyltransferase
SAAV_RS08000	COG0517	IMP dehydrogenase activity
SAAV_RS08020	COG0295	cytidine deaminase activity
SAAV_RS08035	COG1702	phosphate starvation-inducible protein PhoH
SAAV_RS08050	COG1030	water channel activity
SAAV_RS08060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SAAV_RS08065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SAAV_RS08095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAAV_RS08115	COG1466	dna polymerase III delta subunit
SAAV_RS08120	COG0658	competence protein
SAAV_RS08120	COG2333	competence protein COMEC
SAAV_RS08125	COG2131	deaminase
SAAV_RS08130	COG2183	response to ionizing radiation
SAAV_RS08135	COG2226	methyltransferase
SAAV_RS08140	COG0799	negative regulation of ribosome biogenesis
SAAV_RS08145	COG1713	HD superfamily hydrolase involved in NAD metabolism
SAAV_RS08155	COG1534	Rna-binding protein
SAAV_RS08165	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAAV_RS08170	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SAAV_RS08200	COG3177	Filamentation induced by cAMP protein fic
SAAV_RS08210	COG1914	H( )-stimulated, divalent metal cation uptake system
SAAV_RS08220	COG0439	Biotin carboxylase
SAAV_RS08225	COG0511	ligase activity, forming carbon-carbon bonds
SAAV_RS08230	COG1984	allophanate hydrolase subunit 2
SAAV_RS08235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SAAV_RS08250	COG0826	peptidase U32
SAAV_RS08255	COG0826	peptidase U32
SAAV_RS08285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAAV_RS08300	COG1104	cysteine desulfurase activity
SAAV_RS08305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAAV_RS08315	COG3237	CsbD-like
SAAV_RS08320	COG1959	2 iron, 2 sulfur cluster binding
SAAV_RS08325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SAAV_RS08330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SAAV_RS08370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SAAV_RS08370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SAAV_RS08375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAAV_RS08375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAAV_RS08380	COG1862	Preprotein translocase
SAAV_RS08420	COG2868	ribosomal protein
SAAV_RS08460	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SAAV_RS08470	COG0285	dihydrofolate synthase activity
SAAV_RS08480	COG2818	Glycosylase
SAAV_RS08515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SAAV_RS08555	COG4112	unkown
SAAV_RS08580	COG0833	amino acid
SAAV_RS08595	COG1484	DNA-dependent DNA replication
SAAV_RS08625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAAV_RS08625	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAAV_RS08635	COG5002	protein histidine kinase activity
SAAV_RS08640	COG0745	RESPONSE REGULATOR receiver
SAAV_RS08655	COG0372	Belongs to the citrate synthase family
SAAV_RS08660	COG1113	amino acid transport
SAAV_RS08675	COG2826	transposase and inactivated derivatives, IS30 family
SAAV_RS08695	COG1388	LysM domain
SAAV_RS08695	COG3942	CHAP domain
SAAV_RS08700	COG5644	endopeptidase inhibitor activity
SAAV_RS08710	COG1674	ftsk spoiiie
SAAV_RS08730	COG0433	COG0433 Predicted ATPase
SAAV_RS08750	COG2946	Replication initiation factor
SAAV_RS08785	COG0281	malic enzyme
SAAV_RS08795	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SAAV_RS08800	COG4109	DRTGG domain
SAAV_RS08840	COG0827	DNA restriction-modification system
SAAV_RS08850	COG0730	response to heat
SAAV_RS08860	COG1104	cysteine desulfurase activity
SAAV_RS08875	COG1956	GAF domain-containing protein
SAAV_RS08890	COG0584	glycerophosphoryl diester phosphodiesterase
SAAV_RS08895	COG1764	response to oxidative stress
SAAV_RS08900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SAAV_RS08905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAAV_RS08920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAAV_RS08920	COG1263	PTS System
SAAV_RS08925	COG0204	Acyl-transferase
SAAV_RS08930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAAV_RS08965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAAV_RS08970	COG0454	-acetyltransferase
SAAV_RS08990	COG1605	Chorismate mutase
SAAV_RS08990	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SAAV_RS09015	COG1674	ftsk spoiiie
SAAV_RS09020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAAV_RS09030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAAV_RS09035	COG1363	Peptidase, m42
SAAV_RS09045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAAV_RS09055	COG0510	thiamine kinase activity
SAAV_RS09075	COG1187	pseudouridine synthase activity
SAAV_RS09080	COG2244	polysaccharide biosynthetic process
SAAV_RS09085	COG2081	HI0933 family
SAAV_RS09105	COG2814	Major facilitator Superfamily
SAAV_RS09110	COG1242	4 iron, 4 sulfur cluster binding
SAAV_RS09115	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SAAV_RS09125	COG2267	carboxylic ester hydrolase activity
SAAV_RS09155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAAV_RS09155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAAV_RS09175	COG5632	N-Acetylmuramoyl-L-alanine amidase
SAAV_RS09175	COG3266	domain, Protein
SAAV_RS09175	COG4193	domain, Protein
SAAV_RS09205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SAAV_RS09245	COG0656	L-ascorbic acid biosynthetic process
SAAV_RS09265	COG1506	peptidase
SAAV_RS09270	COG2816	NAD+ diphosphatase activity
SAAV_RS09525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SAAV_RS09555	COG1131	(ABC) transporter
SAAV_RS09560	COG0537	adenosine 5'-monophosphoramidase activity
SAAV_RS09590	COG0420	3'-5' exonuclease activity
SAAV_RS09615	COG2197	response regulator
SAAV_RS09620	COG4585	Histidine kinase
SAAV_RS09620	COG2203	Gaf domain
SAAV_RS09625	COG0564	pseudouridine synthase activity
SAAV_RS09655	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SAAV_RS09660	COG1126	abc transporter atp-binding protein
SAAV_RS09665	COG0765	amino acid transport
SAAV_RS09835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAAV_RS09840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SAAV_RS09850	COG4129	membrane
SAAV_RS09875	COG1988	membrane-bound metal-dependent
SAAV_RS09890	COG1388	LysM domain
SAAV_RS09890	COG1134	teichoic acid transport
SAAV_RS09920	COG0535	radical SAM domain protein
SAAV_RS09940	COG2946	Replication initiation factor
SAAV_RS09960	COG0433	COG0433 Predicted ATPase
SAAV_RS09965	COG1674	ftsk spoiiie
SAAV_RS09995	COG2826	transposase and inactivated derivatives, IS30 family
SAAV_RS10000	COG1607	acyl-coa hydrolase
SAAV_RS10005	COG2309	aminopeptidase activity
SAAV_RS10025	COG1295	ribonuclease BN
SAAV_RS10145	COG4851	CamS sex pheromone cAM373 precursor
SAAV_RS10165	COG4496	protein, YerC YecD
SAAV_RS10200	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SAAV_RS10210	COG0077	Prephenate dehydratase
SAAV_RS10220	COG0471	metal ion transport
SAAV_RS10230	COG1335	isochorismatase
SAAV_RS10245	COG1012	belongs to the aldehyde dehydrogenase family
SAAV_RS10295	COG1131	(ABC) transporter
SAAV_RS10310	COG1725	Transcriptional regulator
SAAV_RS10360	COG1388	LysM domain
SAAV_RS10360	COG0860	N-Acetylmuramoyl-L-alanine amidase
SAAV_RS10415	COG3953	SLT domain
SAAV_RS10415	COG5412	phage tail tape measure protein
SAAV_RS10690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAAV_RS10755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAAV_RS10760	COG1621	beta-fructofuranosidase activity
SAAV_RS10765	COG1609	Transcriptional regulator
SAAV_RS10770	COG0004	ammonium transporteR
SAAV_RS10775	COG0425	Belongs to the sulfur carrier protein TusA family
SAAV_RS10780	COG2391	methyltransferase activity
SAAV_RS10790	COG0488	(ABC) transporter
SAAV_RS10800	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SAAV_RS10810	COG0456	acetyltransferase
SAAV_RS10815	COG1214	PFAM Peptidase M22, glycoprotease
SAAV_RS10820	COG0802	atpase or kinase
SAAV_RS10835	COG0028	Belongs to the TPP enzyme family
SAAV_RS10905	COG2183	response to ionizing radiation
SAAV_RS10915	COG1191	sigma factor activity
SAAV_RS10925	COG1366	Belongs to the anti-sigma-factor antagonist family
SAAV_RS10930	COG2208	phosphoserine phosphatase activity
SAAV_RS10965	COG3428	Bacterial PH domain
SAAV_RS10995	COG2205	protein histidine kinase activity
SAAV_RS11000	COG0745	RESPONSE REGULATOR receiver
SAAV_RS11010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAAV_RS11020	COG0772	Belongs to the SEDS family
SAAV_RS11035	COG1937	Protein conserved in bacteria
SAAV_RS11045	COG1418	mRNA catabolic process
SAAV_RS11090	COG0629	single-stranded DNA binding
SAAV_RS11165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAAV_RS11190	COG0009	L-threonylcarbamoyladenylate synthase
SAAV_RS11195	COG2890	protein-(glutamine-N5) methyltransferase activity
SAAV_RS11215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SAAV_RS11255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAAV_RS11305	COG0813	purine-nucleoside phosphorylase activity
SAAV_RS11310	COG0783	Belongs to the Dps family
SAAV_RS11330	COG1482	cell wall glycoprotein biosynthetic process
SAAV_RS11335	COG0702	epimerase
SAAV_RS11340	COG0640	Transcriptional regulator
SAAV_RS11360	COG0561	phosphatase activity
SAAV_RS11365	COG1119	ATPase activity
SAAV_RS11380	COG3711	transcriptional antiterminator
SAAV_RS11410	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SAAV_RS11470	COG0489	protein tyrosine kinase activity
SAAV_RS11475	COG2814	Major facilitator Superfamily
SAAV_RS11490	COG1272	protein, Hemolysin III
SAAV_RS11500	COG1988	membrane-bound metal-dependent
SAAV_RS11510	COG3314	Sporulation integral membrane protein YlbJ
SAAV_RS11515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAAV_RS11520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAAV_RS11525	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAAV_RS11535	COG3457	Alanine racemase
SAAV_RS11540	COG4264	IucA IucC family
SAAV_RS11545	COG2814	Major facilitator Superfamily
SAAV_RS11570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAAV_RS11580	COG2130	NADP-dependent
SAAV_RS11645	COG0656	L-ascorbic acid biosynthetic process
SAAV_RS11650	COG0789	Transcriptional regulator
SAAV_RS11660	COG5492	domain, Protein
SAAV_RS11680	COG3527	Alpha-acetolactate decarboxylase
SAAV_RS11685	COG0028	Belongs to the TPP enzyme family
SAAV_RS11790	COG0201	protein transport
SAAV_RS11905	COG2252	PERMEase
SAAV_RS12015	COG1763	Mo-molybdopterin cofactor biosynthetic process
SAAV_RS12035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SAAV_RS12040	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SAAV_RS12045	COG4149	molybdate abc transporter
SAAV_RS12050	COG0725	ABC transporter, periplasmic molybdate-binding protein
SAAV_RS12065	COG1268	BioY protein
SAAV_RS12080	COG1960	acyl-CoA dehydrogenase activity
SAAV_RS12085	COG4413	Urea transporter
SAAV_RS12150	COG3942	CHAP domain
SAAV_RS12160	COG1757	Na H antiporter
SAAV_RS12175	COG3942	CHAP domain
SAAV_RS12245	COG1113	amino acid transport
SAAV_RS12265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAAV_RS12270	COG0385	Bile acid
SAAV_RS12280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAAV_RS12280	COG1263	PTS System
SAAV_RS12285	COG1737	Transcriptional regulator
SAAV_RS12305	COG1028	Short-chain dehydrogenase reductase Sdr
SAAV_RS12310	COG1473	amidohydrolase
SAAV_RS12325	COG0583	DNA-binding transcription factor activity
SAAV_RS12350	COG2258	MOSC domain
SAAV_RS12370	COG1668	transmembrane transport
SAAV_RS12375	COG4152	abc transporter atp-binding protein
SAAV_RS12380	COG3152	Membrane
SAAV_RS12390	COG0786	glutamate:sodium symporter activity
SAAV_RS12400	COG0598	Magnesium transport protein CorA
SAAV_RS12415	COG0657	acetylesterase activity
SAAV_RS12425	COG2814	Major facilitator Superfamily
SAAV_RS12430	COG1566	PFAM secretion protein HlyD family protein
SAAV_RS12440	COG2814	Major facilitator Superfamily
SAAV_RS12505	COG1620	l-lactate permease
SAAV_RS12525	COG0604	alcohol dehydrogenase
SAAV_RS12555	COG1511	domain protein
SAAV_RS12570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAAV_RS12570	COG1263	PTS System
SAAV_RS12585	COG3871	stress protein (general stress protein 26)
SAAV_RS12625	COG0789	Transcriptional regulator
SAAV_RS12645	COG2181	nitrate reductase activity
SAAV_RS12655	COG1140	nitrate reductase beta subunit
SAAV_RS12660	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SAAV_RS12670	COG2146	nitrite reductase [NAD(P)H] activity
SAAV_RS12675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SAAV_RS12685	COG0454	-acetyltransferase
SAAV_RS12690	COG2116	formate transmembrane transporter activity
SAAV_RS12705	COG3443	Belongs to the bacterial solute-binding protein 9 family
SAAV_RS12705	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAAV_RS12740	COG1126	abc transporter atp-binding protein
SAAV_RS12745	COG0765	amino acid transport
SAAV_RS12750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAAV_RS12755	COG2814	Major facilitator Superfamily
SAAV_RS12775	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SAAV_RS12820	COG0156	8-amino-7-oxononanoate synthase activity
SAAV_RS12830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SAAV_RS12835	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SAAV_RS12850	COG1132	(ABC) transporter
SAAV_RS12855	COG2375	cellular response to nickel ion
SAAV_RS12855	COG1132	(ABC) transporter
SAAV_RS12875	COG1929	Belongs to the glycerate kinase type-1 family
SAAV_RS12885	COG2814	Major facilitator Superfamily
SAAV_RS12905	COG1113	amino acid transport
SAAV_RS12920	COG0531	amino acid
SAAV_RS12945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAAV_RS12955	COG1174	glycine betaine transport
SAAV_RS12965	COG1174	glycine betaine transport
SAAV_RS12985	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SAAV_RS12990	COG0531	amino acid
SAAV_RS12995	COG2272	Belongs to the type-B carboxylesterase lipase family
SAAV_RS13000	COG2814	Major facilitator Superfamily
SAAV_RS13005	COG0390	transport system, permease component
SAAV_RS13010	COG4619	ABC transporter
SAAV_RS13015	COG1363	Peptidase, m42
SAAV_RS13035	COG4808	Protein conserved in bacteria
SAAV_RS13040	COG0069	glutamate synthase activity
SAAV_RS13095	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SAAV_RS13100	COG1028	Short-chain dehydrogenase reductase Sdr
SAAV_RS13105	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SAAV_RS13110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAAV_RS13200	COG0494	nUDIX hydrolase
SAAV_RS13240	COG1846	Transcriptional regulator
SAAV_RS13275	COG1070	Carbohydrate kinase
SAAV_RS13280	COG1802	Transcriptional regulator
SAAV_RS13285	COG0789	Transcriptional regulator
SAAV_RS13290	COG2357	RelA SpoT domain protein
SAAV_RS13295	COG4876	unkown
SAAV_RS13305	COG2271	Major facilitator Superfamily
SAAV_RS13310	COG0586	Pfam SNARE associated Golgi protein
SAAV_RS13320	COG1131	(ABC) transporter
SAAV_RS13340	COG3949	Membrane
SAAV_RS13345	COG0400	carboxylic ester hydrolase activity
SAAV_RS13350	COG0346	lactoylglutathione lyase activity
SAAV_RS13355	COG1846	Transcriptional regulator
SAAV_RS13365	COG2514	catechol 2,3-dioxygenase activity
SAAV_RS13380	COG0561	phosphatase activity
SAAV_RS13385	COG1131	(ABC) transporter
SAAV_RS13395	COG3764	Sortase (surface protein transpeptidase)
SAAV_RS13415	COG1760	l-serine dehydratase
SAAV_RS13420	COG1760	l-serine dehydratase
SAAV_RS13435	COG0697	spore germination
SAAV_RS13440	COG0657	acetylesterase activity
SAAV_RS13460	COG0028	Belongs to the TPP enzyme family
SAAV_RS13475	COG0583	DNA-binding transcription factor activity
SAAV_RS13485	COG3942	CHAP domain
SAAV_RS13495	COG3425	synthase
SAAV_RS13500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SAAV_RS13525	COG2409	Drug exporters of the RND superfamily
SAAV_RS13570	COG0436	Aminotransferase
SAAV_RS13600	COG3942	CHAP domain
SAAV_RS13605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAAV_RS13605	COG2755	lipolytic protein G-D-S-L family
SAAV_RS13715	COG3001	Fructosamine kinase
SAAV_RS13720	COG0167	dihydroorotate dehydrogenase activity
SAAV_RS13780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAAV_RS13785	COG3527	Alpha-acetolactate decarboxylase
SAAV_RS13800	COG0531	amino acid
SAAV_RS13830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAAV_RS13850	COG1012	belongs to the aldehyde dehydrogenase family
SAAV_RS13860	COG1510	regulation of RNA biosynthetic process
SAAV_RS13865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAAV_RS13890	COG2851	Citrate transporter
SAAV_RS13905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SAAV_RS13915	COG0386	Belongs to the glutathione peroxidase family
SAAV_RS13940	COG1136	(ABC) transporter
SAAV_RS13945	COG2205	protein histidine kinase activity
SAAV_RS13950	COG0745	RESPONSE REGULATOR receiver
SAAV_RS13965	COG1785	Belongs to the alkaline phosphatase family
SAAV_RS13970	COG1846	Transcriptional regulator
SAAV_RS14015	COG1438	arginine binding
SAAV_RS14040	COG3711	transcriptional antiterminator
SAAV_RS14040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAAV_RS14045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAAV_RS14045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAAV_RS14045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAAV_RS14050	COG1482	cell wall glycoprotein biosynthetic process
SAAV_RS14060	COG3942	CHAP domain
SAAV_RS14060	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAAV_RS14065	COG1535	isochorismatase
SAAV_RS14065	COG3433	isochorismatase activity
SAAV_RS14080	COG0438	transferase activity, transferring glycosyl groups
SAAV_RS14095	COG1073	alpha beta
SAAV_RS14115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAAV_RS14135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAAV_RS14225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SAAV_RS14310	COG0471	metal ion transport
SAAV_RS14315	COG2962	Rard protein
SAAV_RS14325	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SAAV_RS14340	COG1136	(ABC) transporter
SAAV_RS14345	COG0577	efflux transmembrane transporter activity
SAAV_RS14355	COG1278	Cold shock
SAAV_RS14375	COG1475	DNA binding