locus-tag	class	description
HLB22_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HLB22_RS00015	ENOG410848D	S4 domain protein YaaA
HLB22_RS00030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLB22_RS00035	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HLB22_RS00060	ENOG4105DWV	Homoserine O-trans-acetylase
HLB22_RS00070	ENOG4105BZR	domain protein
HLB22_RS00080	ENOG4105CDU	Replicative dna helicase
HLB22_RS00085	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HLB22_RS00120	ENOG4105Q2H	domain protein
HLB22_RS00125	ENOG4105CGH	5'-nucleotidase
HLB22_RS00145	ENOG4108BUD	transposase
HLB22_RS00155	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HLB22_RS00160	ENOG4108ZMQ	domain protein
HLB22_RS00165	ENOG4107RVG	penicillin-binding protein
HLB22_RS00170	ENOG4105CCN	Peptidase M56
HLB22_RS00270	ENOG4108WS4	fmn reductase
HLB22_RS00320	ENOG4105DZR	Type I site-specific deoxyribonuclease
HLB22_RS00330	ENOG4105CVR	type I restriction-modification system
HLB22_RS00375	ENOG4108NQ3	Phosphatidylinositol-specific phospholipase C
HLB22_RS00400	ENOG4105C57	major facilitator superfamily
HLB22_RS00410	ENOG4105CCI	Myosin-Cross-Reactive Antigen
HLB22_RS00435	ENOG4108IHU	transport system permease protein
HLB22_RS00440	ENOG4105DQ5	transport system permease protein
HLB22_RS00445	ENOG4108MES	Periplasmic binding protein
HLB22_RS00455	ENOG4105CIF	Ornithine Cyclodeaminase
HLB22_RS00460	ENOG4105DJU	Siderophore biosynthesis protein
HLB22_RS00465	ENOG4105C6X	Major Facilitator
HLB22_RS00470	ENOG4105DBM	Siderophore biosynthesis protein
HLB22_RS00475	ENOG4105DUU	IucA IucC family protein
HLB22_RS00485	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HLB22_RS00490	ENOG41067FT	ParB-like nuclease domain
HLB22_RS00505	ENOG4105CHR	reductase
HLB22_RS00515	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HLB22_RS00525	ENOG4105CPK	Glycosyl transferase (Group 1
HLB22_RS00540	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HLB22_RS00550	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HLB22_RS00555	ENOG4108J8C	transporter major facilitator family protein
HLB22_RS00560	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HLB22_RS00595	ENOG4105CGH	5'-nucleotidase
HLB22_RS00600	ENOG4108RS6	transposase
HLB22_RS00610	ENOG4105C0A	alcohol dehydrogenase
HLB22_RS00615	ENOG4108RS6	transposase
HLB22_RS00640	ENOG4105C5E	polysaccharide biosynthesis protein
HLB22_RS00650	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HLB22_RS00680	ENOG4105D3Q	Sugar transferase
HLB22_RS00695	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HLB22_RS00705	ENOG4105WD1	Membrane
HLB22_RS00715	ENOG4105PGM	cation diffusion facilitator family transporter
HLB22_RS00750	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
HLB22_RS00785	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HLB22_RS00795	ENOG4105C8Y	Acetylornithine aminotransferase
HLB22_RS00800	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HLB22_RS00805	ENOG4105D3W	isochorismatase
HLB22_RS00810	ENOG4107RA9	decarboxylase
HLB22_RS00840	ENOG4105QEK	Transcriptional regulator
HLB22_RS00875	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLB22_RS00880	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB22_RS00890	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HLB22_RS00925	ENOG4105EG2	ABC transporter, permease
HLB22_RS00935	ENOG4105CK5	oxidoreductase
HLB22_RS00945	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
HLB22_RS00950	ENOG4105CXY	transporter
HLB22_RS01000	ENOG4105CHU	acetyl-coa acetyltransferase
HLB22_RS01005	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HLB22_RS01010	ENOG4105C1G	acyl-Coa dehydrogenase
HLB22_RS01015	ENOG4105CEY	Amp-dependent synthetase and ligase
HLB22_RS01020	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
HLB22_RS01035	ENOG4107RRN	ABC transporter substrate-binding protein
HLB22_RS01040	ENOG4105K78	MarR family Transcriptional regulator
HLB22_RS01065	ENOG4105CI1	PTS System
HLB22_RS01070	ENOG4105DU0	nucleoside hydrolase
HLB22_RS01090	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
HLB22_RS01095	ENOG4105DT3	PTS system, galactitol-specific IIc component
HLB22_RS01100	ENOG4105CPQ	Dehydrogenase
HLB22_RS01110	ENOG4105CPQ	Dehydrogenase
HLB22_RS01115	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HLB22_RS01120	ENOG4105EJJ	Dehydrogenase
HLB22_RS01125	ENOG4107RZX	Teichoic acid biosynthesis protein
HLB22_RS01130	ENOG4107SJB	teichoic acid biosynthesis
HLB22_RS01140	ENOG4105EJJ	Dehydrogenase
HLB22_RS01145	ENOG4107RZX	Teichoic acid biosynthesis protein
HLB22_RS01160	ENOG4108HRK	Histidine kinase
HLB22_RS01180	ENOG4105DSQ	Nitric oxide reductase
HLB22_RS01185	ENOG4108S3Y	transcriptional regulator
HLB22_RS01190	ENOG4105CI1	PTS System
HLB22_RS01195	ENOG4105CS2	ec 3.2.1.21
HLB22_RS01200	ENOG4105DVA	methyltransferase
HLB22_RS01220	ENOG4105EV1	Ribose uptake protein RbsU
HLB22_RS01255	ENOG4105CJ1	ABC, transporter
HLB22_RS01275	ENOG4105VRS	hydrolase family 18
HLB22_RS01390	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
HLB22_RS01395	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
HLB22_RS01420	ENOG4105D9N	nucleoside
HLB22_RS01425	ENOG4107RJ1	sodium solute
HLB22_RS01435	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
HLB22_RS01440	ENOG4106KNT	transcriptional regulator
HLB22_RS01450	ENOG4105DWD	nucleoside recognition domain protein
HLB22_RS01475	ENOG4105DEN	Luciferase family
HLB22_RS01505	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HLB22_RS01515	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
HLB22_RS01520	ENOG4105CID	antiterminator
HLB22_RS01540	ENOG4105CXY	transporter
HLB22_RS01555	ENOG4107V0Z	fmn reductase
HLB22_RS01560	ENOG4105HMI	Membrane
HLB22_RS01570	ENOG410650H	(LipO)protein
HLB22_RS01580	ENOG4107SJW	iron permease, FTR1
HLB22_RS01585	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HLB22_RS01590	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HLB22_RS01600	ENOG4105VZ8	Transcriptional regulator
HLB22_RS01610	ENOG4105CJ1	ABC, transporter
HLB22_RS01645	ENOG4105C28	cystathionine
HLB22_RS01650	ENOG4105C28	cystathionine
HLB22_RS01655	ENOG4105FA0	parb-like partition protein
HLB22_RS01660	ENOG4105D8X	mechanosensitive ion channel
HLB22_RS01665	ENOG4105VDK	protein, conserved in bacteria
HLB22_RS01670	ENOG4105C3G	gtp-binding protein
HLB22_RS01685	ENOG4108UUM	single-stranded DNA-binding protein
HLB22_RS01755	ENOG4108JU3	Alkyl hydroperoxide reductase
HLB22_RS01760	ENOG4105D3R	alkyl hydroperoxide reductase
HLB22_RS01770	ENOG4107R6U	sodium dicarboxylate symporter
HLB22_RS01800	ENOG4105C2W	permease
HLB22_RS01805	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HLB22_RS01845	ENOG4105KA3	membrAne
HLB22_RS01960	ENOG4105CKI	cobalamin synthesis protein
HLB22_RS01985	ENOG4108TWJ	NADH dehydrogenase subunit 5
HLB22_RS01995	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
HLB22_RS02020	ENOG4105C8J	)-transporter
HLB22_RS02030	ENOG4105C28	cystathionine
HLB22_RS02040	ENOG4108UMI	ABC transporter, permease
HLB22_RS02045	ENOG4105D01	(LipO)protein
HLB22_RS02060	ENOG4105M6F	mutator MutT protein
HLB22_RS02080	ENOG4105C5Q	Transcriptional regulator
HLB22_RS02085	ENOG4105CBC	glutamate synthase
HLB22_RS02090	ENOG4105BZ8	glutamate synthase
HLB22_RS02100	ENOG4105C5Y	PTS System
HLB22_RS02105	ENOG4105CG3	alpha amylase, catalytic region
HLB22_RS02110	ENOG4107414	GntR family transcriptional regulator
HLB22_RS02130	ENOG4105C6E	dna polymerase iii
HLB22_RS02165	ENOG4105CXN	decarboxylase
HLB22_RS02175	ENOG4105X0R	protein from nitrogen regulatory protein P-II
HLB22_RS02180	ENOG4105FA2	dna polymerase iii
HLB22_RS02185	ENOG4105MA4	psp1 domain protein
HLB22_RS02195	ENOG41060K3	Methyltransferase
HLB22_RS02205	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HLB22_RS02210	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HLB22_RS02215	ENOG4105F8V	Hydrolase, tatD family
HLB22_RS02220	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
HLB22_RS02230	ENOG4105W42	Veg protein
HLB22_RS02240	ENOG4105DFT	pur operon repressor
HLB22_RS02245	ENOG4105KME	endoribonuclease L-psp
HLB22_RS02265	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HLB22_RS02290	ENOG4108IY2	MazG family
HLB22_RS02295	ENOG41082I2	s4 domain protein
HLB22_RS02305	ENOG41060GV	RNA binding s1 domain protein
HLB22_RS02315	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HLB22_RS02320	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HLB22_RS02330	ENOG4105C6T	cysteine synthase
HLB22_RS02335	ENOG4105EEI	dihydropteroate synthase
HLB22_RS02340	ENOG4105KRF	dihydroneopterin aldolase
HLB22_RS02345	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLB22_RS02440	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLB22_RS02455	ENOG4105D9N	nucleoside
HLB22_RS02465	ENOG4108Z0C	Uvrb UvrC protein
HLB22_RS02480	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HLB22_RS02485	ENOG4105CTP	PilT protein domain protein
HLB22_RS02505	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLB22_RS02535	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HLB22_RS02560	ENOG4107Y49	methyltransferase
HLB22_RS02570	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HLB22_RS02625	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HLB22_RS02630	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HLB22_RS02635	ENOG4105ZMH	deoxynucleoside kinase
HLB22_RS02645	ENOG4108Z6B	deaminase
HLB22_RS02650	ENOG410667J	hydrolase
HLB22_RS02690	ENOG4107YEI	lmbE family
HLB22_RS02720	ENOG4105CSH	Transporter
HLB22_RS02725	ENOG4107F3J	Amp-dependent synthetase and ligase
HLB22_RS02750	ENOG4105DWF	phosphomethylpyrimidine kinase
HLB22_RS02790	ENOG4108IJ2	phosphate acetyltransferase
HLB22_RS02795	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
HLB22_RS02800	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HLB22_RS02820	ENOG4107QN2	dihydrolipoyl dehydrogenase
HLB22_RS02855	ENOG4105CPC	Aldo Keto reductase
HLB22_RS02860	ENOG4108WS4	fmn reductase
HLB22_RS02870	ENOG4105DCI	Phosphohydrolase
HLB22_RS02875	ENOG4108XFG	YwhD family
HLB22_RS02905	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HLB22_RS02920	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HLB22_RS02960	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLB22_RS03000	ENOG4105EEQ	Na H antiporter
HLB22_RS03005	ENOG4105DSE	periplasmic solute binding protein
HLB22_RS03010	ENOG4105CC5	ABC transporter
HLB22_RS03015	ENOG4105DIK	(ABC) transporter
HLB22_RS03020	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
HLB22_RS03030	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
HLB22_RS03055	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
HLB22_RS03065	ENOG4105BZ1	(ABC) transporter
HLB22_RS03080	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
HLB22_RS03085	ENOG4105E0A	ABC, transporter
HLB22_RS03090	ENOG4105DQ5	transport system permease protein
HLB22_RS03095	ENOG4105EHG	Permease protein
HLB22_RS03100	ENOG4105CMT	Dihydroxyacetone kinase
HLB22_RS03120	ENOG4108K88	Membrane
HLB22_RS03155	ENOG4105C19	ABC transporter
HLB22_RS03165	ENOG4107GRR	phosphate transport regulator
HLB22_RS03170	ENOG4105CJ3	phosphate transporter
HLB22_RS03175	ENOG4105VRS	hydrolase family 18
HLB22_RS03185	ENOG4105ID8	Transcriptional regulator, ARAC family
HLB22_RS03225	ENOG4105S8Q	sugar efflux transporter
HLB22_RS03230	ENOG4105SXS	Protein of unknown function (DUF456)
HLB22_RS03255	ENOG4108YYQ	gCN5-related N-acetyltransferase
HLB22_RS03260	ENOG4108URH	decarboxylase
HLB22_RS03280	ENOG4108JJ9	ABC, transporter
HLB22_RS03285	ENOG4108JJ8	(ABC) transporter
HLB22_RS03290	ENOG4105K56	Transcriptional regulator
HLB22_RS03295	ENOG4105CKI	cobalamin synthesis protein
HLB22_RS03300	ENOG4107QM2	Aldo Keto reductase
HLB22_RS03310	ENOG4107QPK	)-transporter
HLB22_RS03315	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HLB22_RS03345	ENOG4108Z66	YbaK ebsC protein
HLB22_RS03350	ENOG4105E98	transcriptional regulator DeoR family
HLB22_RS03355	ENOG4105DE4	1-phosphofructokinase
HLB22_RS03360	ENOG4105DM4	PTS System
HLB22_RS03365	ENOG4105CE4	GlcNAc 6-P deacetylase
HLB22_RS03370	ENOG4105C37	(CBS) domain
HLB22_RS03380	ENOG4105CKK	Glycosyl transferase, family 2
HLB22_RS03410	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HLB22_RS03415	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
HLB22_RS03425	ENOG4105DDQ	anthranilate synthase
HLB22_RS03430	ENOG4105CRQ	synthase (Component I)
HLB22_RS03460	ENOG4105C5H	ABC transporter
HLB22_RS03465	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HLB22_RS03470	ENOG4108IJ8	ABC transporter
HLB22_RS03475	ENOG4105E90	ABC transporter
HLB22_RS03485	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
HLB22_RS03500	ENOG4105DUX	Transporter
HLB22_RS03520	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLB22_RS03525	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLB22_RS03530	ENOG4105DHS	permease protein
HLB22_RS03535	ENOG4105CM4	permease protein
HLB22_RS03540	ENOG4108IPW	abc transporter atp-binding protein
HLB22_RS03600	ENOG4105ESV	Glycosyl transferase, family 4
HLB22_RS03605	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HLB22_RS03610	ENOG4105EPR	degv family
HLB22_RS03620	ENOG41081UC	Inherit from COG: Competence protein
HLB22_RS03650	ENOG41068JE	domain protein
HLB22_RS03665	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HLB22_RS03670	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HLB22_RS03685	ENOG4108S4C	acetyltransferase
HLB22_RS03695	ENOG4105C3M	thioredoxin reductase
HLB22_RS03705	ENOG4105CHW	UPF0052 protein
HLB22_RS03720	ENOG4105C6K	Malic enzyme
HLB22_RS03740	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HLB22_RS03755	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HLB22_RS03770	ENOG4105XZU	Preprotein translocase, subunit SecG
HLB22_RS03780	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HLB22_RS03815	ENOG4106HV3	Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps
HLB22_RS03835	ENOG4107Y9E	nuclease
HLB22_RS03840	ENOG4105VEQ	Cold shock protein
HLB22_RS03880	ENOG4105CVJ	phosphoglycerate mutase
HLB22_RS03885	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HLB22_RS03910	ENOG4105SZ6	Thioredoxin
HLB22_RS03915	ENOG41080E8	Transcriptional regulator, Spx MgsR family
HLB22_RS03925	ENOG4108XI2	Domain of unknown function (DUF1963)
HLB22_RS03945	ENOG4108UMI	ABC transporter, permease
HLB22_RS03950	ENOG4105D01	(LipO)protein
HLB22_RS03965	ENOG4105C3K	feS assembly ATPase SufC
HLB22_RS03970	ENOG4105JRK	feS assembly protein SufD
HLB22_RS03975	ENOG4105C9B	Cysteine desulfurase
HLB22_RS03980	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HLB22_RS04015	ENOG4105I3N	Conserved Protein
HLB22_RS04035	ENOG4105MMD	transcriptional regulator
HLB22_RS04075	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HLB22_RS04085	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
HLB22_RS04090	ENOG41083MR	nifu domain-containing protein
HLB22_RS04110	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HLB22_RS04120	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HLB22_RS04130	ENOG4105KA0	thioesterase Superfamily protein
HLB22_RS04185	ENOG41060GV	RNA binding s1 domain protein
HLB22_RS04190	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLB22_RS04195	ENOG4105C8Y	Acetylornithine aminotransferase
HLB22_RS04200	ENOG4105D82	Glutamate dehydrogenase
HLB22_RS04205	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HLB22_RS04235	ENOG4105C3F	Signal peptidase i
HLB22_RS04265	ENOG4108KP7	hydrolase
HLB22_RS04275	ENOG4105EXC	Acyl-transferase
HLB22_RS04280	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HLB22_RS04290	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HLB22_RS04305	ENOG4105KIS	phospholipid-binding protein
HLB22_RS04325	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HLB22_RS04335	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLB22_RS04340	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB22_RS04350	ENOG4108JQ7	(ABC) transporter
HLB22_RS04360	ENOG4105DEF	Extracellular solute-binding protein, family 5
HLB22_RS04370	ENOG4108JQ7	(ABC) transporter
HLB22_RS04380	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB22_RS04390	ENOG4105C31	Tryptophanyl-tRNA synthetase
HLB22_RS04395	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HLB22_RS04400	ENOG4108RS6	transposase
HLB22_RS04415	ENOG4105DPN	Oligoendopeptidase f
HLB22_RS04425	ENOG4108Z18	K06886 hemoglobin
HLB22_RS04450	ENOG4105EMS	pseudouridine synthase
HLB22_RS04455	ENOG4105CJW	magnesium transporter
HLB22_RS04470	ENOG4105C02	permease
HLB22_RS04475	ENOG4105BZG	amino acid carrier protein
HLB22_RS04515	ENOG4107TS3	membrane protein, TerC
HLB22_RS04530	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HLB22_RS04545	ENOG4105XVF	Competence transcription factor
HLB22_RS04635	ENOG4105YB8	TM2 domain containing protein
HLB22_RS04645	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HLB22_RS04650	ENOG4105E4F	Isochorismate synthase
HLB22_RS04660	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HLB22_RS04665	ENOG4108IPT	Naphthoate synthase
HLB22_RS04680	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
HLB22_RS04685	ENOG4105CHM	Aminotransferase
HLB22_RS04690	ENOG4108TGC	Acyltransferase
HLB22_RS04710	ENOG4108HPG	-acetyltransferase
HLB22_RS04720	ENOG4108KGH	TRANSCRIPTIONal
HLB22_RS04760	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HLB22_RS04765	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HLB22_RS04775	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
HLB22_RS04790	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HLB22_RS04800	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HLB22_RS04810	ENOG4105C12	Phosphoribosylglycinamide synthetase
HLB22_RS04815	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HLB22_RS04820	ENOG4108JJB	ABC transporter
HLB22_RS04825	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
HLB22_RS04840	ENOG4105DR4	Methyltransferase
HLB22_RS04850	ENOG4105KRI	phosphocarrier protein (HPr
HLB22_RS04860	ENOG41067VN	Glutaredoxin
HLB22_RS04875	ENOG4107ZYR	domain protein
HLB22_RS04895	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HLB22_RS04905	ENOG4107RUY	(E1 component), alpha subunit
HLB22_RS04910	ENOG4105CPP	Dehydrogenase, E1 component
HLB22_RS04915	ENOG4105C7S	Dehydrogenase
HLB22_RS04920	ENOG4107QN2	dihydrolipoyl dehydrogenase
HLB22_RS04940	ENOG4105F38	ABC transporter, permease
HLB22_RS04945	ENOG4105D38	putrescine abc transporter
HLB22_RS04950	ENOG4107RUE	extracellular solute-binding protein family 1
HLB22_RS04975	ENOG4105ECY	inositol monophosphatase
HLB22_RS04985	ENOG4105CI3	gtp-binding protein typa
HLB22_RS05005	ENOG4105CNI	cell division protein FtsW
HLB22_RS05055	ENOG4106H78	methyltransferase
HLB22_RS05110	ENOG4105KFN	sortase, SrtB family
HLB22_RS05125	ENOG4108RWN	rrna methyltransferase
HLB22_RS05155	ENOG4105DCG	PHP domain protein
HLB22_RS05165	ENOG4105K63	Thioredoxin
HLB22_RS05180	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
HLB22_RS05190	ENOG4105E33	succinate dehydrogenase
HLB22_RS05270	ENOG4106UK0	Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity
HLB22_RS05300	ENOG4105DBV	ornithine carbamoyltransferase
HLB22_RS05310	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HLB22_RS05370	ENOG41068DC	Essential cell division protein (By similarity)
HLB22_RS05375	ENOG4105CJN	penicillin-binding protein
HLB22_RS05390	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
HLB22_RS05395	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HLB22_RS05400	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HLB22_RS05410	ENOG4105DFA	alanine racemase domain protein
HLB22_RS05420	ENOG41067XK	integral membrane protein
HLB22_RS05425	ENOG4105DBK	s4 domain protein
HLB22_RS05440	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HLB22_RS05455	ENOG4105C34	Pseudouridine synthase
HLB22_RS05475	ENOG4105CD3	dihydroorotase
HLB22_RS05480	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HLB22_RS05495	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HLB22_RS05525	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HLB22_RS05530	ENOG4105C25	Primosomal protein n'
HLB22_RS05555	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HLB22_RS05565	ENOG4108ZF3	Phosphatase
HLB22_RS05575	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HLB22_RS05580	ENOG4105DJV	ribulose-phosphate 3-epimerase
HLB22_RS05595	ENOG4108ZAA	Alkaline-shock protein
HLB22_RS05605	ENOG4105CB5	ATP-dependent DNA helicase recG
HLB22_RS05620	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HLB22_RS05625	ENOG4105CHR	reductase
HLB22_RS05640	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HLB22_RS05645	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLB22_RS05685	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HLB22_RS05700	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HLB22_RS05715	ENOG4105C79	DNA protecting protein DprA
HLB22_RS05780	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HLB22_RS05785	ENOG4105KNE	Phosphatidate cytidylyltransferase
HLB22_RS05790	ENOG4105DZP	Membrane-associated zinc metalloprotease
HLB22_RS05810	ENOG4105CHV	Transcription elongation factor NusA
HLB22_RS05815	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
HLB22_RS05840	ENOG4105DTN	riboflavin biosynthesis protein ribF
HLB22_RS05865	ENOG4105FDP	GntR family transcriptional regulator
HLB22_RS05880	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
HLB22_RS05895	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HLB22_RS05900	ENOG4105CEV	competence damage-inducible protein
HLB22_RS05925	ENOG4105D48	metallophosphoesterase
HLB22_RS05930	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
HLB22_RS05935	ENOG4105DQU	oxidoreductase, subunit beta
HLB22_RS05970	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
HLB22_RS05975	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HLB22_RS06000	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HLB22_RS06005	ENOG4108V06	Glutathione peroxidase
HLB22_RS06010	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HLB22_RS06015	ENOG4105CXI	aluminum resistance protein
HLB22_RS06020	ENOG4105KV4	Transcriptional regulator
HLB22_RS06090	ENOG4105EKQ	RNA-directed DNA polymerase
HLB22_RS06150	ENOG4108M15	ABC transporter
HLB22_RS06165	ENOG4108S01	response regulator
HLB22_RS06190	ENOG4105CFH	Aspartokinase
HLB22_RS06195	ENOG4105D6E	homoserine dehydrogenase
HLB22_RS06200	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
HLB22_RS06225	ENOG4108IQI	permease
HLB22_RS06250	ENOG4105K4I	Scp-like extracellular
HLB22_RS06265	ENOG4105VPS	UPF0291 protein
HLB22_RS06270	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HLB22_RS06305	ENOG4105C94	Transporter
HLB22_RS06310	ENOG4108I0Z	Aconitate hydratase
HLB22_RS06340	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLB22_RS06370	ENOG4108FKN	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HLB22_RS06375	ENOG4108RCF	TRANSCRIPTIONal
HLB22_RS06385	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HLB22_RS06395	ENOG4105DER	m42 family
HLB22_RS06400	ENOG4105CRQ	synthase (Component I)
HLB22_RS06405	ENOG4105DDQ	anthranilate synthase
HLB22_RS06440	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
HLB22_RS06465	ENOG4106128	DNA-binding helix-turn-helix protein
HLB22_RS06500	ENOG4106BHR	ftsk SpoIIIE family protein
HLB22_RS06530	ENOG4105F9F	transposase
HLB22_RS06540	ENOG4108KP7	hydrolase
HLB22_RS06580	ENOG4105DPN	Oligoendopeptidase f
HLB22_RS06585	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HLB22_RS06595	ENOG4105E2Z	phosphate ABC transporter (Permease
HLB22_RS06600	ENOG4105C8U	phosphate abc transporter
HLB22_RS06615	ENOG4105C5H	ABC transporter
HLB22_RS06620	ENOG4105CFH	Aspartokinase
HLB22_RS06625	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HLB22_RS06650	ENOG4108XFP	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HLB22_RS06655	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HLB22_RS06695	ENOG4107T89	von Willebrand factor, type A
HLB22_RS06700	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
HLB22_RS06730	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLB22_RS06745	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HLB22_RS06770	ENOG4105C5Y	PTS System
HLB22_RS06785	ENOG4108RCR	degv family
HLB22_RS06790	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HLB22_RS06840	ENOG4107R7I	amino acid
HLB22_RS06860	ENOG410890F	Dynamin family
HLB22_RS06875	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HLB22_RS06905	ENOG4105BZ4	penicillin-binding protein
HLB22_RS06915	ENOG4105CSM	endonuclease III
HLB22_RS06945	ENOG4105CPK	Glycosyl transferase (Group 1
HLB22_RS06950	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
HLB22_RS07000	ENOG4105EAH	synthase
HLB22_RS07015	ENOG4105K70	DNA-binding protein
HLB22_RS07030	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HLB22_RS07050	ENOG4105HDK	L-asparaginase
HLB22_RS07055	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
HLB22_RS07070	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HLB22_RS07125	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
HLB22_RS07185	ENOG4108FKH	Transglycosylase SLT domain
HLB22_RS07310	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HLB22_RS07475	ENOG4105BZU	Histidine kinase
HLB22_RS07480	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLB22_RS07485	ENOG4105FE9	pseudouridine synthase
HLB22_RS07505	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLB22_RS07510	ENOG4105I3K	Ferric uptake regulator, Fur family
HLB22_RS07515	ENOG4108YZ4	nudix hydrolase
HLB22_RS07520	ENOG4105CPC	Aldo Keto reductase
HLB22_RS07530	ENOG4105PDP	Short chain dehydrogenase
HLB22_RS07535	ENOG4105II7	pyrroline-5-carboxylate reductase
HLB22_RS07545	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HLB22_RS07580	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HLB22_RS07590	ENOG4108QEG	Membrane
HLB22_RS07600	ENOG4105C7S	Dehydrogenase
HLB22_RS07605	ENOG4105CPP	Dehydrogenase, E1 component
HLB22_RS07620	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HLB22_RS07650	ENOG4108ZSR	alkaline shock protein
HLB22_RS07655	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HLB22_RS07670	ENOG4105DC7	peptidase M24
HLB22_RS07685	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
HLB22_RS07690	ENOG4105WZW	rhodanese family
HLB22_RS07735	ENOG4106855	Competence protein
HLB22_RS07740	ENOG4105D7Q	type ii secretion system
HLB22_RS07750	ENOG4105C5X	domain protein
HLB22_RS07775	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HLB22_RS07785	ENOG4107RF6	penicillin-binding protein
HLB22_RS07790	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HLB22_RS07795	ENOG4105N80	Ferric uptake regulator, Fur family
HLB22_RS07800	ENOG4105FAV	ABC, transporter
HLB22_RS07805	ENOG4105FDK	ABC transporter
HLB22_RS07815	ENOG4105C1J	atp-dependent rna helicase
HLB22_RS07820	ENOG4105EGD	dinuclear metal center protein, YbgI family
HLB22_RS07830	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLB22_RS07835	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HLB22_RS07865	ENOG4105KG3	cytidine deaminase
HLB22_RS07880	ENOG4105C9A	Phoh family
HLB22_RS07895	ENOG4105F7J	membrane-bound serine protease
HLB22_RS07905	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HLB22_RS07910	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HLB22_RS07940	ENOG4105CSA	Coproporphyrinogen iii oxidase
HLB22_RS07955	ENOG4105TQK	DNA polymerase iii, delta' subunit
HLB22_RS07960	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HLB22_RS07965	ENOG4108UK2	deaminase
HLB22_RS07970	ENOG4105BZM	domain protein
HLB22_RS07975	ENOG4105DXX	methyltransferase
HLB22_RS07980	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HLB22_RS07985	ENOG4108WF2	Metal Dependent Phosphohydrolase
HLB22_RS07995	ENOG410812S	Rna-binding protein
HLB22_RS08005	ENOG4105CQW	ribosome biogenesis GTPase YqeH
HLB22_RS08010	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HLB22_RS08035	ENOG4105C5A	transporter
HLB22_RS08045	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HLB22_RS08050	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HLB22_RS08060	ENOG4105P4J	Allophanate hydrolase, subunit 1
HLB22_RS08075	ENOG4105CFP	Peptidase U32
HLB22_RS08080	ENOG4105XYU	peptidase (U32 family)
HLB22_RS08110	ENOG4105C7H	Helicase, RecD TraA family
HLB22_RS08125	ENOG4105C3J	Cysteine desulfurase
HLB22_RS08130	ENOG4105DEN	Luciferase family
HLB22_RS08140	ENOG41061M1	UPF0337 protein
HLB22_RS08150	ENOG4105D1H	recombination factor protein RarA
HLB22_RS08155	ENOG4105CUZ	uba thif-type nad fad binding protein
HLB22_RS08180	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HLB22_RS08200	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HLB22_RS08205	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HLB22_RS08210	ENOG4105VIE	preprotein translocase, subunit YajC
HLB22_RS08250	ENOG4105X36	(ribosomal) protein
HLB22_RS08295	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
HLB22_RS08300	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HLB22_RS08310	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HLB22_RS08330	ENOG4105D52	delta-aminolevulinic acid dehydratase
HLB22_RS08380	ENOG4105U6W	MutT NUDIX family protein
HLB22_RS08400	ENOG4108IQI	permease
HLB22_RS08435	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HLB22_RS08445	ENOG4105C2M	dna polymerase I
HLB22_RS08455	ENOG4105BZU	Histidine kinase
HLB22_RS08460	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HLB22_RS08470	ENOG4105BZN	citrate synthase
HLB22_RS08475	ENOG4105C85	amino acid
HLB22_RS08500	ENOG4105C6K	Malic enzyme
HLB22_RS08510	ENOG4105SFS	phosphoesterase RecJ domain protein
HLB22_RS08565	ENOG4105EJ9	Membrane
HLB22_RS08600	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HLB22_RS08605	ENOG4108X3M	OsmC Ohr family protein
HLB22_RS08610	ENOG4105C5R	Aminotransferase
HLB22_RS08615	ENOG4108JQ1	Dehydrogenase
HLB22_RS08635	ENOG4105F6E	Acyl-transferase
HLB22_RS08640	ENOG4105C0H	protease
HLB22_RS08680	ENOG4105F1V	Acetoin utilization protein
HLB22_RS08685	ENOG4105DGU	Histone deacetylase
HLB22_RS08690	ENOG4105ETE	Transcriptional regulator (LacI family
HLB22_RS08700	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HLB22_RS08730	ENOG4108VDD	TRNA binding domain protein
HLB22_RS08755	ENOG4105C8F	Beta-lactamase domain protein
HLB22_RS08765	ENOG4108V15	phosphotransferase enzyme family
HLB22_RS08795	ENOG4105CBX	hi0933 family
HLB22_RS08815	ENOG410605W	Major Facilitator
HLB22_RS08820	ENOG4105N5T	Radical SAM Protein
HLB22_RS08840	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
HLB22_RS08865	ENOG4108R6K	riboflavin synthase, subunit alpha
HLB22_RS08870	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HLB22_RS08895	ENOG4105DP8	Major facilitator superfamily MFS_1
HLB22_RS08905	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
HLB22_RS08940	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HLB22_RS08950	ENOG4105WMR	Protein CrcB homolog
HLB22_RS08955	ENOG4105WMR	Protein CrcB homolog
HLB22_RS08965	ENOG4105CV8	reductase
HLB22_RS09110	ENOG4105C79	DNA protecting protein DprA
HLB22_RS09205	ENOG4105C1Q	protoporphyrinogen oxidase
HLB22_RS09210	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HLB22_RS09240	ENOG4105K59	histidine triad (HIT) protein
HLB22_RS09270	ENOG4107VRP	DNA repair exonuclease
HLB22_RS09290	ENOG4105WH1	Two component transcriptional regulator luxr family
HLB22_RS09295	ENOG4105BZU	Histidine kinase
HLB22_RS09300	ENOG4108YBP	pseudouridine synthase
HLB22_RS09330	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HLB22_RS09335	ENOG4105CDA	abc transporter atp-binding protein
HLB22_RS09340	ENOG4105E5Q	amino acid AbC transporter
HLB22_RS09360	ENOG4108RS6	transposase
HLB22_RS09525	ENOG4108M3J	Dehydrogenase
HLB22_RS09530	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLB22_RS09540	ENOG4107NBY	Membrane
HLB22_RS09565	ENOG41067AE	Membrane-bound metal-dependent hydrolase
HLB22_RS09575	ENOG4105EY8	ABC transporter
HLB22_RS09595	ENOG4108Z0Z	intracellular protease Pfpi family
HLB22_RS09610	ENOG4108S4H	thioesterase Superfamily protein
HLB22_RS09635	ENOG4107U9T	Pfam:Ribonuclease_BN
HLB22_RS09645	ENOG4105ENE	Histidine kinase
HLB22_RS09660	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HLB22_RS09760	ENOG4105C4R	Atp-dependent dna helicase
HLB22_RS09770	ENOG4105KGF	protein, YerC YecD
HLB22_RS09810	ENOG4105DAP	Nicotinate phosphoribosyltransferase
HLB22_RS09815	ENOG4107QN4	Catalyzes the production of nitric oxide (By similarity)
HLB22_RS09820	ENOG4105CQC	Prephenate dehydratase
HLB22_RS09830	ENOG4105C8P	)-transporter
HLB22_RS09855	ENOG4105C26	Dehydrogenase
HLB22_RS09890	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLB22_RS09895	ENOG4108FPN	Integrase
HLB22_RS09940	ENOG4105CJ1	ABC, transporter
HLB22_RS09955	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HLB22_RS10015	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
HLB22_RS10060	ENOG4105DR5	peptidase
HLB22_RS10110	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HLB22_RS10165	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HLB22_RS10340	ENOG4105CZN	Potassium uptake protein
HLB22_RS10355	ENOG4108TFU	terminase (Small subunit)
HLB22_RS10445	ENOG4105BZU	Histidine kinase
HLB22_RS10455	ENOG4105CUC	YeeE YedE family protein
HLB22_RS10465	ENOG4105C5H	ABC transporter
HLB22_RS10480	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HLB22_RS10490	ENOG410801F	ribosomal-protein-alanine acetyltransferase
HLB22_RS10495	ENOG41072GX	Peptidase M22 Glycoprotease
HLB22_RS10500	ENOG4105K8N	protein family UPF0079, ATPase
HLB22_RS10515	ENOG4105C7K	acetolactate synthase
HLB22_RS10535	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HLB22_RS10610	ENOG4105WN5	stage II sporulation protein
HLB22_RS10615	ENOG4107SGM	protein serine threonine phosphatase
HLB22_RS10645	ENOG4105CKV	Membrane
HLB22_RS10660	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HLB22_RS10690	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HLB22_RS10715	ENOG4105VPX	protein, conserved in bacteria
HLB22_RS10720	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HLB22_RS10745	ENOG4105DWF	phosphomethylpyrimidine kinase
HLB22_RS10835	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HLB22_RS10855	ENOG4107WAU	Protein tyrosine phosphatase
HLB22_RS10860	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HLB22_RS10865	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HLB22_RS10885	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HLB22_RS10900	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HLB22_RS10905	ENOG4105D2N	Aldolase
HLB22_RS10965	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HLB22_RS10970	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HLB22_RS10975	ENOG4108RMU	ferritin dps family protein
HLB22_RS10995	ENOG4105DG6	mannose-6-phosphate isomerase
HLB22_RS11010	ENOG4105PGM	cation diffusion facilitator family transporter
HLB22_RS11040	ENOG4105DKW	ABC transporter
HLB22_RS11045	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HLB22_RS11055	ENOG4105ETD	TRANSCRIPTIONal
HLB22_RS11060	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HLB22_RS11085	ENOG4105C8B	TIGR00159 family
HLB22_RS11145	ENOG4105D1F	ATP-binding protein
HLB22_RS11165	ENOG4108UT2	hemolysin iii
HLB22_RS11175	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
HLB22_RS11185	ENOG4105DWD	nucleoside recognition domain protein
HLB22_RS11190	ENOG4108U1V	ABC transporter, permease
HLB22_RS11195	ENOG4105DQ5	transport system permease protein
HLB22_RS11200	ENOG4108HUF	Transporter
HLB22_RS11210	ENOG4106M28	alanine racemase domain protein
HLB22_RS11220	ENOG4107SFI	Major Facilitator superfamily
HLB22_RS11230	ENOG4105VBF	alkaline shock protein
HLB22_RS11245	ENOG4105C94	Transporter
HLB22_RS11255	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HLB22_RS11270	ENOG4105CK1	PTS System
HLB22_RS11275	ENOG4105VCP	PTS System
HLB22_RS11305	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HLB22_RS11330	ENOG4105VUF	Transcriptional regulator
HLB22_RS11340	ENOG4106AM8	polysaccharide lyase family 8
HLB22_RS11355	ENOG4105CG5	Glycosyl transferase (Group 1
HLB22_RS11370	ENOG4107FQX	Alpha-acetolactate decarboxylase
HLB22_RS11455	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HLB22_RS11460	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HLB22_RS11575	ENOG4105C7N	Xanthine uracil vitamin C permease
HLB22_RS11595	ENOG4105CSC	Glucose uptake protein
HLB22_RS11640	ENOG41065XD	Transcriptional regulator
HLB22_RS11675	ENOG4108ZAF	Molybdopterin
HLB22_RS11680	ENOG4108129	molybdopterin-guanine dinucleotide biosynthesis protein
HLB22_RS11695	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
HLB22_RS11700	ENOG4105D06	uba thif-type nad fad binding protein
HLB22_RS11705	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HLB22_RS11710	ENOG4105E0C	molybdate abc transporter
HLB22_RS11715	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HLB22_RS11730	ENOG4107ZYJ	bioY protein
HLB22_RS11745	ENOG4105FDT	acyl-CoA dehydrogenase
HLB22_RS11820	ENOG4105DFD	Na H antiporter
HLB22_RS11850	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
HLB22_RS11920	ENOG4107YBY	Hydrolase
HLB22_RS11925	ENOG4105C09	Bile acid
HLB22_RS11935	ENOG4105CI1	PTS System
HLB22_RS11940	ENOG4108Q3X	Transcriptional regulator
HLB22_RS11960	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HLB22_RS11965	ENOG4105CH2	amidohydrolase
HLB22_RS11980	ENOG4105C5Q	Transcriptional regulator
HLB22_RS12000	ENOG4108RPX	mosc domain containing protein
HLB22_RS12020	ENOG4105RHA	ABC transporter, permease
HLB22_RS12025	ENOG4108IUX	(ABC) transporter
HLB22_RS12030	ENOG4105KAF	membrAne
HLB22_RS12040	ENOG4105D6U	Sodium Glutamate Symporter
HLB22_RS12050	ENOG4105D7N	magnesium and cobalt transport protein CorA
HLB22_RS12075	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLB22_RS12080	ENOG4105CW7	secretion protein, HlyD family
HLB22_RS12090	ENOG4105C2C	drug resistance transporter, Bcr CflA
HLB22_RS12150	ENOG4105CJ1	ABC, transporter
HLB22_RS12215	ENOG4105ECB	domain protein
HLB22_RS12245	ENOG410606W	general stress protein
HLB22_RS12285	ENOG4107TXC	Transcriptional regulator
HLB22_RS12315	ENOG4108IUE	nitrate reductase beta subunit
HLB22_RS12325	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HLB22_RS12330	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
HLB22_RS12335	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HLB22_RS12345	ENOG4108XSB	acetyltransferase, (GNAT) family
HLB22_RS12350	ENOG4105TMB	Formate nitrite transporter
HLB22_RS12365	ENOG4105DSE	periplasmic solute binding protein
HLB22_RS12400	ENOG4105CDA	abc transporter atp-binding protein
HLB22_RS12405	ENOG4105DRP	amino acid AbC transporter
HLB22_RS12410	ENOG4105EAB	amino acid AbC transporter
HLB22_RS12470	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HLB22_RS12480	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HLB22_RS12485	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HLB22_RS12500	ENOG4105BZ1	(ABC) transporter
HLB22_RS12520	ENOG4105BZW	Glycerate kinase
HLB22_RS12530	ENOG4105C2C	drug resistance transporter, Bcr CflA
HLB22_RS12550	ENOG4105C85	amino acid
HLB22_RS12555	ENOG4105EEQ	Na H antiporter
HLB22_RS12560	ENOG4105C0X	amino acid
HLB22_RS12565	ENOG4105ED2	Beta-lactamase
HLB22_RS12575	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HLB22_RS12580	ENOG4105C57	major facilitator superfamily
HLB22_RS12585	ENOG4105R40	Glycine betaine carnitine choline
HLB22_RS12595	ENOG4105E90	ABC transporter
HLB22_RS12615	ENOG4105CZ9	Domain of unknown function (DU1801)
HLB22_RS12620	ENOG4107QTZ	amino acid
HLB22_RS12625	ENOG4105EBR	Carboxylesterase
HLB22_RS12630	ENOG4105F27	Major Facilitator
HLB22_RS12635	ENOG4105C4B	ABC transporter, permease
HLB22_RS12640	ENOG41083J0	(ABC) transporter
HLB22_RS12645	ENOG4105CN9	Peptidase m42 family protein
HLB22_RS12660	ENOG4105PQ4	(LipO)protein
HLB22_RS12665	ENOG4105CBC	glutamate synthase
HLB22_RS12680	ENOG4108S9F	abc transporter, atp-binding protein
HLB22_RS12690	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLB22_RS12700	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HLB22_RS12725	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HLB22_RS12730	ENOG4105CFC	Transporter
HLB22_RS12735	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HLB22_RS12770	ENOG4106128	DNA-binding helix-turn-helix protein
HLB22_RS12810	ENOG4106BHR	ftsk SpoIIIE family protein
HLB22_RS12820	ENOG41068JE	domain protein
HLB22_RS12840	ENOG4105F9F	transposase
HLB22_RS12925	ENOG4105M6F	mutator MutT protein
HLB22_RS12990	ENOG4105CMG	Carbohydrate kinase
HLB22_RS12995	ENOG4105G3Z	GntR family transcriptional regulator
HLB22_RS13010	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
HLB22_RS13020	ENOG4105DJB	Major Facilitator Superfamily
HLB22_RS13025	ENOG4107T5V	SNARE associated Golgi
HLB22_RS13045	ENOG4105CJ1	ABC, transporter
HLB22_RS13060	ENOG4108K88	Membrane
HLB22_RS13065	ENOG4105FBA	Phospholipase Carboxylesterase
HLB22_RS13075	ENOG41090MY	MarR family Transcriptional regulator
HLB22_RS13080	ENOG410830R	acetyltransferase
HLB22_RS13085	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HLB22_RS13095	ENOG4105C5I	Dehydrogenase
HLB22_RS13105	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
HLB22_RS13110	ENOG4108Z15	abc transporter atp-binding protein
HLB22_RS13115	ENOG4106KKU	
HLB22_RS13120	ENOG4108Z6X	(sortase) family
HLB22_RS13125	ENOG4108Z7F	N-acetyltransferase
HLB22_RS13140	ENOG4105EJQ	L-serine dehydratase
HLB22_RS13160	ENOG4108UZ3	Transporter
HLB22_RS13195	ENOG41067MG	lrgb family
HLB22_RS13205	ENOG4105CMU	LysR family (Transcriptional regulator
HLB22_RS13215	ENOG41068JE	domain protein
HLB22_RS13225	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
HLB22_RS13230	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HLB22_RS13255	ENOG4105EYF	MMPL domain protein
HLB22_RS13275	ENOG4108UW5	maltose o-acetyltransferase
HLB22_RS13335	ENOG4105EXC	Acyl-transferase
HLB22_RS13370	ENOG4105VPS	UPF0291 protein
HLB22_RS13395	ENOG4105CHR	reductase
HLB22_RS13405	ENOG4108SXP	alpha beta
HLB22_RS13425	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
HLB22_RS13450	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HLB22_RS13505	ENOG4108NKJ	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HLB22_RS13510	ENOG4107FQX	Alpha-acetolactate decarboxylase
HLB22_RS13515	ENOG4108RS6	transposase
HLB22_RS13525	ENOG4105CUB	amino acid
HLB22_RS13530	ENOG4108JPW	Aminotransferase
HLB22_RS13545	ENOG4105DWT	malate dehydrogenase (quinone)
HLB22_RS13555	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HLB22_RS13585	ENOG4105TRT	Transcriptional regulator
HLB22_RS13590	ENOG4105C94	Transporter
HLB22_RS13605	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HLB22_RS13610	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HLB22_RS13615	ENOG4105D4T	Citrate transporter
HLB22_RS13625	ENOG4108Z73	Siroheme synthase
HLB22_RS13630	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HLB22_RS13680	ENOG4105G6Z	alkaline phosphatase
HLB22_RS13690	ENOG4108U05	Transcriptional regulator
HLB22_RS13710	ENOG4105C5B	carbamate kinase
HLB22_RS13720	ENOG4105DBV	ornithine carbamoyltransferase
HLB22_RS13760	ENOG4105DM4	PTS System
HLB22_RS13765	ENOG4105DG6	mannose-6-phosphate isomerase
HLB22_RS13775	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
HLB22_RS13780	ENOG4105WQI	isochorismatase
HLB22_RS13805	ENOG4106E62	Accessory Sec system protein Asp3
HLB22_RS13810	ENOG41089G2	accessory Sec system protein Asp2
HLB22_RS13815	ENOG4108XJK	accessory Sec system protein Asp1
HLB22_RS13830	ENOG4105EW6	flavin reductase domain protein, FMN-binding
HLB22_RS13850	ENOG4107XC4	flavin reductase domain protein, FMN-binding
HLB22_RS13855	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HLB22_RS13875	ENOG4105HTX	biosynthesis protein
HLB22_RS13885	ENOG4107QJZ	Glycosyl transferase, family 2
HLB22_RS13905	ENOG4105J1V	Triacylglycerol lipase
HLB22_RS13915	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HLB22_RS13940	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HLB22_RS14000	ENOG4107QPK	)-transporter
HLB22_RS14005	ENOG4105FR1	rard protein
HLB22_RS14015	ENOG4105D9G	High-affinity
HLB22_RS14030	ENOG4105C19	ABC transporter
HLB22_RS14045	ENOG4105VEQ	Cold shock protein
HLB22_RS14065	ENOG4108RS6	transposase
HLB22_RS14070	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)