locus-tag	class	description
RT44_RS00015	COG2501	S4 domain
RT44_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RT44_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RT44_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RT44_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RT44_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
RT44_RS00110	COG4863	YycH protein
RT44_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RT44_RS00125	COG0737	Belongs to the 5'-nucleotidase family
RT44_RS00160	COG0584	glycerophosphoryl diester phosphodiesterase
RT44_RS00165	COG2030	dehydratase
RT44_RS00220	COG3226	Transcriptional regulator
RT44_RS00245	COG2226	methyltransferase
RT44_RS00255	COG0456	acetyltransferase
RT44_RS00265	COG2378	regulation of single-species biofilm formation
RT44_RS00385	COG0823	Involved in the tonB-independent uptake of proteins
RT44_RS00425	COG1473	amidohydrolase
RT44_RS00440	COG1283	sodium-dependent phosphate transmembrane transporter activity
RT44_RS00445	COG4716	Myosin-crossreactive antigen
RT44_RS00455	COG1620	l-lactate permease
RT44_RS00470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT44_RS00475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT44_RS00480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RT44_RS00490	COG2423	ornithine cyclodeaminase activity
RT44_RS00495	COG4264	IucA IucC family
RT44_RS00500	COG2814	Major facilitator Superfamily
RT44_RS00505	COG4264	IucA IucC family
RT44_RS00510	COG4264	IucA IucC family
RT44_RS00520	COG0019	diaminopimelate decarboxylase activity
RT44_RS00525	COG1475	DNA binding
RT44_RS00550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RT44_RS00555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RT44_RS00560	COG0438	transferase activity, transferring glycosyl groups
RT44_RS00595	COG0813	purine-nucleoside phosphorylase activity
RT44_RS00600	COG2814	Major facilitator Superfamily
RT44_RS00620	COG3639	organic phosphonate transmembrane transporter activity
RT44_RS00640	COG0737	Belongs to the 5'-nucleotidase family
RT44_RS00670	COG1012	belongs to the aldehyde dehydrogenase family
RT44_RS00670	COG1454	alcohol dehydrogenase
RT44_RS00705	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RT44_RS00735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RT44_RS00745	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RT44_RS00750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RT44_RS00760	COG2832	Protein of unknown function (DUF454)
RT44_RS00800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RT44_RS00805	COG1960	acyl-CoA dehydrogenase activity
RT44_RS00810	COG5609	conserved protein (DUF2294)
RT44_RS00860	COG1114	Component of the transport system for branched-chain amino acids
RT44_RS00865	COG1335	isochorismatase
RT44_RS00870	COG3961	Belongs to the TPP enzyme family
RT44_RS00900	COG1737	Transcriptional regulator
RT44_RS00935	COG0601	transmembrane transport
RT44_RS00940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RT44_RS00950	COG0405	Gamma-glutamyltransferase
RT44_RS00970	COG3842	ATPase activity
RT44_RS00980	COG1175	transmembrane transport
RT44_RS00985	COG3833	ABC-type maltose transport systems, permease component
RT44_RS00990	COG0673	inositol 2-dehydrogenase activity
RT44_RS00995	COG0673	inositol 2-dehydrogenase activity
RT44_RS01005	COG1755	Isoprenylcysteine carboxyl methyltransferase
RT44_RS01070	COG0183	Belongs to the thiolase family
RT44_RS01080	COG1960	acyl-CoA dehydrogenase activity
RT44_RS01085	COG0318	PFAM AMP-dependent synthetase and ligase
RT44_RS01100	COG0747	negative chemotaxis
RT44_RS01105	COG3189	MarR family transcriptional regulator
RT44_RS01135	COG2190	(PTS) system
RT44_RS01135	COG1263	PTS System
RT44_RS01135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RT44_RS01140	COG1957	nucleoside hydrolase
RT44_RS01165	COG3414	Phosphotransferase system galactitol-specific IIB component
RT44_RS01170	COG3775	system Galactitol-specific IIC component
RT44_RS01175	COG1063	alcohol dehydrogenase
RT44_RS01185	COG1063	alcohol dehydrogenase
RT44_RS01195	COG1063	alcohol dehydrogenase
RT44_RS01200	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RT44_RS01205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RT44_RS01215	COG1063	alcohol dehydrogenase
RT44_RS01220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RT44_RS01255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RT44_RS01260	COG1263	PTS System
RT44_RS01260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RT44_RS01260	COG2190	(PTS) system
RT44_RS01265	COG2723	6-phospho-beta-galactosidase activity
RT44_RS01270	COG2226	methyltransferase
RT44_RS01330	COG1131	(ABC) transporter
RT44_RS01350	COG3942	CHAP domain
RT44_RS01350	COG1388	LysM domain
RT44_RS01475	COG1114	Component of the transport system for branched-chain amino acids
RT44_RS01480	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
RT44_RS01490	COG0577	efflux transmembrane transporter activity
RT44_RS01515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RT44_RS01520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RT44_RS01545	COG3314	Sporulation integral membrane protein YlbJ
RT44_RS01570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RT44_RS01600	COG3037	sugar-specific permease SgaT UlaA
RT44_RS01610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RT44_RS01615	COG3711	transcriptional antiterminator
RT44_RS01635	COG2271	Major facilitator Superfamily
RT44_RS01640	COG0346	lactoylglutathione lyase activity
RT44_RS01645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RT44_RS01650	COG0431	NADPH-dependent FMN reductase
RT44_RS01665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RT44_RS01670	COG2822	iron ion transport
RT44_RS01680	COG0672	)-iron permease
RT44_RS01685	COG0805	protein transport
RT44_RS01690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RT44_RS01700	COG1476	TRANSCRIPTIONal
RT44_RS01710	COG1131	(ABC) transporter
RT44_RS01745	COG0646	methionine synthase
RT44_RS01745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RT44_RS01750	COG0626	cystathionine gamma-synthase activity
RT44_RS01755	COG0626	cystathionine gamma-synthase activity
RT44_RS01760	COG1475	DNA binding
RT44_RS01765	COG0668	transmembrane transport
RT44_RS01770	COG4481	Protein conserved in bacteria
RT44_RS01775	COG0012	GTP binding
RT44_RS01860	COG3634	alkyl hydroperoxide reductase activity
RT44_RS01875	COG1823	symporter activity
RT44_RS01905	COG2233	PERMEase
RT44_RS01980	COG1683	Conserved Protein
RT44_RS01990	COG3759	membrane
RT44_RS02145	COG0523	cobalamin synthesis protein
RT44_RS02155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RT44_RS02165	COG5609	conserved protein (DUF2294)
RT44_RS02180	COG1647	Serine aminopeptidase, S33
RT44_RS02190	COG0733	neurotransmitter:sodium symporter activity
RT44_RS02195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RT44_RS02200	COG0626	cystathionine gamma-synthase activity
RT44_RS02210	COG2011	ABC-type metal ion transport system permease component
RT44_RS02215	COG1464	Belongs to the NlpA lipoprotein family
RT44_RS02250	COG0583	DNA-binding transcription factor activity
RT44_RS02255	COG0069	glutamate synthase activity
RT44_RS02255	COG0070	glutamate synthase
RT44_RS02255	COG0067	glutamate synthase
RT44_RS02260	COG0493	'glutamate synthase
RT44_RS02270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RT44_RS02270	COG1263	PTS System
RT44_RS02275	COG0366	Alpha amylase catalytic
RT44_RS02280	COG2188	Transcriptional regulator
RT44_RS02295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RT44_RS02330	COG1982	Orn Lys Arg decarboxylase major
RT44_RS02340	COG3870	Protein conserved in bacteria
RT44_RS02350	COG0470	DNA polymerase III
RT44_RS02355	COG1774	PSP1 C-terminal conserved region
RT44_RS02365	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RT44_RS02375	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RT44_RS02390	COG0084	hydrolase, TatD family'
RT44_RS02395	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RT44_RS02405	COG4466	Protein conserved in bacteria
RT44_RS02415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RT44_RS02420	COG0251	oxidation-reduction process
RT44_RS02465	COG2244	polysaccharide biosynthetic process
RT44_RS02470	COG3956	TIGRFAM MazG family protein
RT44_RS02475	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RT44_RS02485	COG1098	S1 RNA binding domain
RT44_RS02500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RT44_RS02525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RT44_RS02600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RT44_RS02615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RT44_RS02625	COG3880	PFAM UvrB UvrC protein
RT44_RS02645	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RT44_RS02650	COG4956	integral membrane protein (PIN domain superfamily)
RT44_RS02670	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RT44_RS02720	COG2813	Specifically methylates the guanine in position
RT44_RS02760	COG1473	amidohydrolase
RT44_RS02790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RT44_RS02795	COG1428	Deoxynucleoside kinase
RT44_RS02800	COG1428	Deoxynucleoside kinase
RT44_RS02810	COG0561	phosphatase activity
RT44_RS02850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RT44_RS02955	COG0095	Lipoate-protein ligase
RT44_RS02960	COG0083	homoserine kinase activity
RT44_RS02980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RT44_RS03025	COG0667	Aldo Keto reductase
RT44_RS03030	COG0655	NAD(P)H dehydrogenase (quinone) activity
RT44_RS03040	COG1078	dGTPase activity
RT44_RS03075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RT44_RS03080	COG4139	cobalamin transport
RT44_RS03130	COG4974	Belongs to the 'phage' integrase family
RT44_RS03175	COG0803	Belongs to the bacterial solute-binding protein 9 family
RT44_RS03180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RT44_RS03185	COG1121	(ABC) transporter
RT44_RS03190	COG1321	iron dependent repressor
RT44_RS03200	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RT44_RS03210	COG1682	transport, permease protein
RT44_RS03215	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RT44_RS03220	COG1216	Glycosyl transferase, family 2
RT44_RS03225	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RT44_RS03230	COG1686	Belongs to the peptidase S11 family
RT44_RS03235	COG1132	(ABC) transporter
RT44_RS03240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RT44_RS03250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RT44_RS03255	COG1120	ATPase activity
RT44_RS03260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT44_RS03265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT44_RS03270	COG2376	Dihydroxyacetone kinase
RT44_RS03280	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
RT44_RS03290	COG3949	Membrane
RT44_RS03315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RT44_RS03330	COG1136	(ABC) transporter
RT44_RS03335	COG0577	efflux transmembrane transporter activity
RT44_RS03340	COG1392	Phosphate transport regulator
RT44_RS03345	COG0306	phosphate transporter
RT44_RS03350	COG3942	CHAP domain
RT44_RS03350	COG1388	LysM domain
RT44_RS03360	COG1917	Cupin 2, conserved barrel domain protein
RT44_RS03360	COG4977	sequence-specific DNA binding
RT44_RS03390	COG0583	DNA-binding transcription factor activity
RT44_RS03400	COG2814	Major facilitator Superfamily
RT44_RS03405	COG2839	Protein conserved in bacteria
RT44_RS03435	COG1611	Belongs to the LOG family
RT44_RS03455	COG4988	ABC transporter
RT44_RS03460	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RT44_RS03470	COG0523	cobalamin synthesis protein
RT44_RS03475	COG4989	oxidoreductase activity
RT44_RS03485	COG0471	metal ion transport
RT44_RS03490	COG0415	Belongs to the DNA photolyase family
RT44_RS03520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RT44_RS03525	COG1349	DNA-binding transcription factor activity
RT44_RS03530	COG1105	Belongs to the carbohydrate kinase PfkB family
RT44_RS03535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RT44_RS03535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RT44_RS03535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RT44_RS03545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RT44_RS03550	COG1253	flavin adenine dinucleotide binding
RT44_RS03555	COG0656	L-ascorbic acid biosynthetic process
RT44_RS03560	COG0463	Glycosyl transferase, family 2
RT44_RS03595	COG0720	synthase
RT44_RS03605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RT44_RS03605	COG0512	Glutamine amidotransferase of anthranilate synthase
RT44_RS03610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RT44_RS03645	COG0488	(ABC) transporter
RT44_RS03650	COG0514	ATP-dependent DNA helicase (RecQ)
RT44_RS03655	COG1125	glycine betaine transport
RT44_RS03655	COG0517	IMP dehydrogenase activity
RT44_RS03660	COG1174	glycine betaine transport
RT44_RS03685	COG3104	oligopeptide transport
RT44_RS03705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RT44_RS03710	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RT44_RS03720	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT44_RS03725	COG4605	iron ion homeostasis
RT44_RS03730	COG4604	ABC transporter, ATP-binding protein
RT44_RS03735	COG4607	ABC-type enterochelin transport system periplasmic component
RT44_RS03790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RT44_RS03795	COG1739	Uncharacterized protein family UPF0029
RT44_RS03805	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RT44_RS03810	COG1040	competence protein
RT44_RS03840	COG3942	CHAP domain
RT44_RS03840	COG1388	LysM domain
RT44_RS03900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RT44_RS03965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RT44_RS03970	COG1647	Serine aminopeptidase, S33
RT44_RS03975	COG0557	exoribonuclease II activity
RT44_RS04045	COG1278	Cold shock
RT44_RS04085	COG0406	alpha-ribazole phosphatase activity
RT44_RS04090	COG1279	arginine transmembrane transporter activity
RT44_RS04115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RT44_RS04120	COG1393	Belongs to the ArsC family
RT44_RS04135	COG3878	Protein conserved in bacteria
RT44_RS04140	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RT44_RS04155	COG2011	ABC-type metal ion transport system permease component
RT44_RS04160	COG1464	Belongs to the NlpA lipoprotein family
RT44_RS04175	COG0396	ATPase activity
RT44_RS04180	COG0719	Fe-S assembly protein
RT44_RS04190	COG0822	iron-sulfur transferase activity
RT44_RS04210	COG1253	flavin adenine dinucleotide binding
RT44_RS04225	COG1801	Protein of unknown function DUF72
RT44_RS04230	COG0730	response to heat
RT44_RS04245	COG4470	Protein conserved in bacteria
RT44_RS04255	COG2445	Protein of unknown function DUF86
RT44_RS04285	COG1696	Membrane protein involved in D-alanine export
RT44_RS04295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RT44_RS04300	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RT44_RS04305	COG4837	Protein of unknown function (DUF1462)
RT44_RS04310	COG1252	NADH dehydrogenase
RT44_RS04320	COG0316	Belongs to the HesB IscA family
RT44_RS04330	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RT44_RS04335	COG2056	Na+-H+ antiporter family
RT44_RS04340	COG2050	protein possibly involved in aromatic compounds catabolism
RT44_RS04395	COG1098	S1 RNA binding domain
RT44_RS04400	COG1902	pentaerythritol trinitrate reductase activity
RT44_RS04420	COG0584	glycerophosphoryl diester phosphodiesterase
RT44_RS04440	COG0398	Pfam SNARE associated Golgi protein
RT44_RS04485	COG0561	phosphatase activity
RT44_RS04510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RT44_RS04525	COG1881	PFAM PEBP family protein
RT44_RS04555	COG0601	transmembrane transport
RT44_RS04560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RT44_RS04565	COG0444	Belongs to the ABC transporter superfamily
RT44_RS04570	COG4608	Belongs to the ABC transporter superfamily
RT44_RS04575	COG4166	transmembrane transport
RT44_RS04580	COG0747	negative chemotaxis
RT44_RS04585	COG0444	Belongs to the ABC transporter superfamily
RT44_RS04590	COG4608	Belongs to the ABC transporter superfamily
RT44_RS04595	COG0601	transmembrane transport
RT44_RS04600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RT44_RS04625	COG1164	Oligoendopeptidase f
RT44_RS04635	COG2346	COG2346, Truncated hemoglobins
RT44_RS04650	COG2357	RelA SpoT domain protein
RT44_RS04660	COG0564	pseudouridine synthase activity
RT44_RS04665	COG2239	Acts as a magnesium transporter
RT44_RS04670	COG0569	domain protein
RT44_RS04670	COG0475	glutathione-regulated potassium exporter activity
RT44_RS04680	COG0628	permease
RT44_RS04685	COG1115	amino acid carrier protein
RT44_RS04725	COG0861	Integral membrane protein TerC family
RT44_RS04735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RT44_RS04740	COG0737	Belongs to the 5'-nucleotidase family
RT44_RS04755	COG4903	ComK protein
RT44_RS04770	COG4873	Protein conserved in bacteria
RT44_RS04825	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RT44_RS04835	COG2314	TM2 domain
RT44_RS04840	COG0456	acetyltransferase
RT44_RS04845	COG1575	Belongs to the MenA family. Type 1 subfamily
RT44_RS04850	COG1169	isochorismate synthase
RT44_RS04860	COG2267	carboxylic ester hydrolase activity
RT44_RS04885	COG0436	Aminotransferase
RT44_RS04890	COG3594	Acyltransferase
RT44_RS04920	COG1316	TRANSCRIPTIONal
RT44_RS04925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RT44_RS04970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RT44_RS04985	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RT44_RS05025	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RT44_RS05030	COG4172	Belongs to the ABC transporter superfamily
RT44_RS05035	COG4721	ABC-type cobalt transport system, permease component
RT44_RS05055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RT44_RS05080	COG1271	oxidase subunit
RT44_RS05085	COG1294	oxidase, subunit
RT44_RS05090	COG0569	domain protein
RT44_RS05155	COG1176	ABC-type spermidine putrescine transport system, permease component I
RT44_RS05160	COG1177	transmembrane transport
RT44_RS05165	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RT44_RS05190	COG0483	inositol monophosphate 1-phosphatase activity
RT44_RS05200	COG1217	gtp-binding protein TYPA
RT44_RS05210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RT44_RS05220	COG0772	Belongs to the SEDS family
RT44_RS05255	COG3679	Belongs to the UPF0342 family
RT44_RS05275	COG0742	ribosomal rna small subunit methyltransferase
RT44_RS05335	COG4509	Sortase family
RT44_RS05350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RT44_RS05380	COG1796	DNA polymerase
RT44_RS05380	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RT44_RS05405	COG2009	succinate dehydrogenase
RT44_RS05410	COG1053	succinate dehydrogenase
RT44_RS05415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RT44_RS05545	COG1288	antiporter activity
RT44_RS05580	COG1011	Hydrolase
RT44_RS05605	COG4839	cell division protein FtsL
RT44_RS05610	COG0768	penicillin binding
RT44_RS05625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RT44_RS05630	COG0849	cell division
RT44_RS05645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RT44_RS05655	COG0762	integral membrane protein
RT44_RS05660	COG2302	S4 RNA-binding domain
RT44_RS05665	COG3599	regulation of cell shape
RT44_RS05675	COG2514	catechol 2,3-dioxygenase activity
RT44_RS05690	COG0564	pseudouridine synthase activity
RT44_RS05700	COG2233	PERMEase
RT44_RS05745	COG1293	RNA-binding protein homologous to eukaryotic snRNP
RT44_RS05760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RT44_RS05765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RT44_RS05775	COG2314	TM2 domain
RT44_RS05790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RT44_RS05790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RT44_RS05800	COG0631	protein serine/threonine phosphatase activity
RT44_RS05815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RT44_RS05830	COG1302	Protein conserved in bacteria
RT44_RS05880	COG1196	nuclear chromosome segregation
RT44_RS05885	COG0552	protein localization to endoplasmic reticulum
RT44_RS05895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RT44_RS05955	COG0758	DNA mediated transformation
RT44_RS06050	COG0195	Participates in both transcription termination and antitermination
RT44_RS06055	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RT44_RS06080	COG0196	riboflavin kinase activity
RT44_RS06105	COG2188	Transcriptional regulator
RT44_RS06110	COG0612	Peptidase, M16
RT44_RS06115	COG0612	Peptidase, M16
RT44_RS06120	COG0300	oxidoreductase activity
RT44_RS06140	COG1546	Belongs to the CinA family
RT44_RS06140	COG1058	Belongs to the CinA family
RT44_RS06160	COG1692	metallophosphoesterase
RT44_RS06165	COG0674	pyruvate-flavodoxin oxidoreductase activity
RT44_RS06165	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RT44_RS06170	COG1013	pyruvate-flavodoxin oxidoreductase activity
RT44_RS06205	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RT44_RS06210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RT44_RS06235	COG1923	regulation of RNA biosynthetic process
RT44_RS06245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RT44_RS06250	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RT44_RS06255	COG0789	Transcriptional regulator
RT44_RS06355	COG1525	nuclease
RT44_RS06370	COG0527	aspartate kinase activity
RT44_RS06375	COG0460	homoserine dehydrogenase
RT44_RS06380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RT44_RS06405	COG0833	amino acid
RT44_RS06435	COG2340	Cysteine-rich secretory protein family
RT44_RS06470	COG4846	Membrane protein involved in cytochrome C biogenesis
RT44_RS06490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RT44_RS06500	COG0824	Thioesterase
RT44_RS06520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RT44_RS06530	COG1115	amino acid carrier protein
RT44_RS06545	COG0628	permease
RT44_RS06570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RT44_RS06580	COG1363	Peptidase, m42
RT44_RS06585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RT44_RS06590	COG0512	Glutamine amidotransferase of anthranilate synthase
RT44_RS06635	COG0561	phosphatase activity
RT44_RS06680	COG0704	Plays a role in the regulation of phosphate uptake
RT44_RS06690	COG0581	inorganic phosphate transmembrane transporter activity
RT44_RS06695	COG0573	inorganic phosphate transmembrane transporter activity
RT44_RS06720	COG0488	(ABC) transporter
RT44_RS06725	COG0527	aspartate kinase activity
RT44_RS06730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RT44_RS06805	COG4548	von Willebrand factor, type A
RT44_RS06810	COG0714	Associated with various cellular activities
RT44_RS06855	COG0671	phosphoesterase, PA-phosphatase related
RT44_RS06940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RT44_RS06975	COG0531	amino acid
RT44_RS06990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RT44_RS06995	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RT44_RS07015	COG0116	Belongs to the methyltransferase superfamily
RT44_RS07045	COG4499	WXG100 protein secretion system (Wss), protein YukC
RT44_RS07045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RT44_RS07055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RT44_RS07060	COG3935	DnaD domain protein
RT44_RS07085	COG0438	transferase activity, transferring glycosyl groups
RT44_RS07090	COG1694	Mazg nucleotide pyrophosphohydrolase
RT44_RS07095	COG2738	Putative neutral zinc metallopeptidase
RT44_RS07100	COG4347	Protein of unknown function (DUF1405)
RT44_RS07140	COG0142	geranyltranstransferase activity
RT44_RS07195	COG0492	ferredoxin-NADP+ reductase activity
RT44_RS07210	COG0514	ATP-dependent DNA helicase (RecQ)
RT44_RS07220	COG1141	Ferredoxin
RT44_RS07270	COG1388	LysM domain
RT44_RS07270	COG0860	N-Acetylmuramoyl-L-alanine amidase
RT44_RS07320	COG5412	phage tail tape measure protein
RT44_RS07320	COG3953	SLT domain
RT44_RS07570	COG0582	viral genome integration into host DNA
RT44_RS07590	COG5002	protein histidine kinase activity
RT44_RS07595	COG0745	RESPONSE REGULATOR receiver
RT44_RS07600	COG1187	pseudouridine synthase activity
RT44_RS07625	COG0735	belongs to the Fur family
RT44_RS07630	COG0494	nUDIX hydrolase
RT44_RS07635	COG0667	Aldo Keto reductase
RT44_RS07645	COG4221	oxidoreductase activity
RT44_RS07660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RT44_RS07670	COG0366	Alpha amylase catalytic
RT44_RS07675	COG1609	Transcriptional regulator
RT44_RS07695	COG2195	Cleaves the N-terminal amino acid of tripeptides
RT44_RS07705	COG4129	membrane
RT44_RS07715	COG0508	dehydrogenase complex catalyzes the overall conversion of
RT44_RS07720	COG0022	dehydrogenase e1 component
RT44_RS07725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RT44_RS07730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RT44_RS07735	COG0497	DNA recombination
RT44_RS07765	COG1302	Protein conserved in bacteria
RT44_RS07770	COG0439	Biotin carboxylase
RT44_RS07775	COG0511	ligase activity, forming carbon-carbon bonds
RT44_RS07785	COG0006	proline dipeptidase activity
RT44_RS07800	COG0095	Lipoate-protein ligase
RT44_RS07805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RT44_RS07850	COG4537	Required for transformation and DNA binding
RT44_RS07855	COG1459	type II secretion system
RT44_RS07860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RT44_RS07865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RT44_RS07870	COG0011	TIGRFAM Protein of
RT44_RS07875	COG1940	carbohydrate kinase activity
RT44_RS07880	COG4483	Protein conserved in bacteria
RT44_RS07890	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RT44_RS07900	COG0768	penicillin binding
RT44_RS07915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RT44_RS07920	COG1121	(ABC) transporter
RT44_RS07930	COG0513	Belongs to the DEAD box helicase family
RT44_RS07940	COG2384	SAM-dependent methyltransferase
RT44_RS07960	COG0517	IMP dehydrogenase activity
RT44_RS07980	COG0295	cytidine deaminase activity
RT44_RS07995	COG1702	phosphate starvation-inducible protein PhoH
RT44_RS08010	COG1030	water channel activity
RT44_RS08020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RT44_RS08025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RT44_RS08055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RT44_RS08075	COG1466	dna polymerase III delta subunit
RT44_RS08080	COG0658	competence protein
RT44_RS08080	COG2333	competence protein COMEC
RT44_RS08085	COG2131	deaminase
RT44_RS08095	COG2226	methyltransferase
RT44_RS08100	COG0799	negative regulation of ribosome biogenesis
RT44_RS08105	COG1713	HD superfamily hydrolase involved in NAD metabolism
RT44_RS08115	COG1534	Rna-binding protein
RT44_RS08125	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RT44_RS08130	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RT44_RS08155	COG3177	Filamentation induced by cAMP protein fic
RT44_RS08160	COG1914	H( )-stimulated, divalent metal cation uptake system
RT44_RS08170	COG0439	Biotin carboxylase
RT44_RS08175	COG0511	ligase activity, forming carbon-carbon bonds
RT44_RS08180	COG1984	allophanate hydrolase subunit 2
RT44_RS08185	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RT44_RS08200	COG0826	peptidase U32
RT44_RS08205	COG0826	peptidase U32
RT44_RS08235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RT44_RS08255	COG1104	cysteine desulfurase activity
RT44_RS08260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RT44_RS08270	COG3237	CsbD-like
RT44_RS08275	COG1959	2 iron, 2 sulfur cluster binding
RT44_RS08280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RT44_RS08285	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RT44_RS08325	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RT44_RS08325	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RT44_RS08330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RT44_RS08330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RT44_RS08335	COG1862	Preprotein translocase
RT44_RS08375	COG2868	ribosomal protein
RT44_RS08415	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RT44_RS08425	COG0285	dihydrofolate synthase activity
RT44_RS08435	COG2818	Glycosylase
RT44_RS08470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RT44_RS08505	COG4112	unkown
RT44_RS08530	COG0833	amino acid
RT44_RS08545	COG1484	DNA-dependent DNA replication
RT44_RS08575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RT44_RS08575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RT44_RS08585	COG5002	protein histidine kinase activity
RT44_RS08590	COG0745	RESPONSE REGULATOR receiver
RT44_RS08605	COG0372	Belongs to the citrate synthase family
RT44_RS08610	COG1113	amino acid transport
RT44_RS08635	COG0281	malic enzyme
RT44_RS08645	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RT44_RS08650	COG4109	DRTGG domain
RT44_RS08690	COG0827	DNA restriction-modification system
RT44_RS08710	COG1104	cysteine desulfurase activity
RT44_RS08725	COG1956	GAF domain-containing protein
RT44_RS08740	COG0584	glycerophosphoryl diester phosphodiesterase
RT44_RS08745	COG1764	response to oxidative stress
RT44_RS08750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RT44_RS08755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RT44_RS08770	COG1263	PTS System
RT44_RS08770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RT44_RS08775	COG0204	Acyl-transferase
RT44_RS08780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RT44_RS08810	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RT44_RS08815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RT44_RS08820	COG0454	-acetyltransferase
RT44_RS08840	COG1605	Chorismate mutase
RT44_RS08840	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RT44_RS08865	COG1674	ftsk spoiiie
RT44_RS08870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RT44_RS08880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RT44_RS08885	COG1363	Peptidase, m42
RT44_RS08895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RT44_RS08905	COG0510	thiamine kinase activity
RT44_RS08925	COG1187	pseudouridine synthase activity
RT44_RS08930	COG2244	polysaccharide biosynthetic process
RT44_RS08935	COG2081	HI0933 family
RT44_RS08955	COG2814	Major facilitator Superfamily
RT44_RS08960	COG1242	4 iron, 4 sulfur cluster binding
RT44_RS08965	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RT44_RS08975	COG2267	carboxylic ester hydrolase activity
RT44_RS09005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RT44_RS09005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RT44_RS09025	COG3266	domain, Protein
RT44_RS09025	COG4193	domain, Protein
RT44_RS09025	COG5632	N-Acetylmuramoyl-L-alanine amidase
RT44_RS09055	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RT44_RS09075	COG0656	L-ascorbic acid biosynthetic process
RT44_RS09095	COG1506	peptidase
RT44_RS09100	COG2816	NAD+ diphosphatase activity
RT44_RS09240	COG1131	(ABC) transporter
RT44_RS09350	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
RT44_RS09380	COG1131	(ABC) transporter
RT44_RS09385	COG0537	adenosine 5'-monophosphoramidase activity
RT44_RS09415	COG0420	3'-5' exonuclease activity
RT44_RS09440	COG2197	response regulator
RT44_RS09445	COG2203	Gaf domain
RT44_RS09445	COG4585	Histidine kinase
RT44_RS09450	COG0564	pseudouridine synthase activity
RT44_RS09480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RT44_RS09485	COG1126	abc transporter atp-binding protein
RT44_RS09490	COG0765	amino acid transport
RT44_RS09655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RT44_RS09660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RT44_RS09670	COG4129	membrane
RT44_RS09690	COG1194	a g-specific adenine glycosylase
RT44_RS09695	COG1988	membrane-bound metal-dependent
RT44_RS09710	COG1134	teichoic acid transport
RT44_RS09710	COG1388	LysM domain
RT44_RS09740	COG0535	radical SAM domain protein
RT44_RS09745	COG1607	acyl-coa hydrolase
RT44_RS09750	COG2309	aminopeptidase activity
RT44_RS09770	COG1295	ribonuclease BN
RT44_RS09905	COG4851	CamS sex pheromone cAM373 precursor
RT44_RS09925	COG4496	protein, YerC YecD
RT44_RS09960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RT44_RS09970	COG0077	Prephenate dehydratase
RT44_RS09980	COG0471	metal ion transport
RT44_RS09990	COG1335	isochorismatase
RT44_RS10005	COG1012	belongs to the aldehyde dehydrogenase family
RT44_RS10055	COG1131	(ABC) transporter
RT44_RS10070	COG1725	Transcriptional regulator
RT44_RS10125	COG0860	N-Acetylmuramoyl-L-alanine amidase
RT44_RS10125	COG1388	LysM domain
RT44_RS10135	COG1388	LysM domain
RT44_RS10135	COG5632	N-Acetylmuramoyl-L-alanine amidase
RT44_RS10235	COG4695	Portal protein
RT44_RS10405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RT44_RS10460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RT44_RS10525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RT44_RS10530	COG1621	beta-fructofuranosidase activity
RT44_RS10535	COG1609	Transcriptional regulator
RT44_RS10540	COG0004	ammonium transporteR
RT44_RS10545	COG0425	Belongs to the sulfur carrier protein TusA family
RT44_RS10550	COG2391	methyltransferase activity
RT44_RS10560	COG0488	(ABC) transporter
RT44_RS10570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RT44_RS10580	COG0456	acetyltransferase
RT44_RS10585	COG1214	PFAM Peptidase M22, glycoprotease
RT44_RS10590	COG0802	atpase or kinase
RT44_RS10605	COG0028	Belongs to the TPP enzyme family
RT44_RS10675	COG2183	response to ionizing radiation
RT44_RS10680	COG1191	sigma factor activity
RT44_RS10690	COG1366	Belongs to the anti-sigma-factor antagonist family
RT44_RS10695	COG2208	phosphoserine phosphatase activity
RT44_RS10730	COG3428	Bacterial PH domain
RT44_RS10760	COG2205	protein histidine kinase activity
RT44_RS10765	COG0745	RESPONSE REGULATOR receiver
RT44_RS10775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RT44_RS10785	COG0772	Belongs to the SEDS family
RT44_RS10800	COG1937	Protein conserved in bacteria
RT44_RS10810	COG1418	mRNA catabolic process
RT44_RS10850	COG0629	single-stranded DNA binding
RT44_RS10925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RT44_RS10950	COG0009	L-threonylcarbamoyladenylate synthase
RT44_RS10955	COG2890	protein-(glutamine-N5) methyltransferase activity
RT44_RS10975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RT44_RS11035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RT44_RS11085	COG0813	purine-nucleoside phosphorylase activity
RT44_RS11090	COG0783	Belongs to the Dps family
RT44_RS11110	COG1482	cell wall glycoprotein biosynthetic process
RT44_RS11115	COG0702	epimerase
RT44_RS11120	COG0640	Transcriptional regulator
RT44_RS11140	COG0561	phosphatase activity
RT44_RS11145	COG1119	ATPase activity
RT44_RS11160	COG3711	transcriptional antiterminator
RT44_RS11190	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RT44_RS11250	COG0489	protein tyrosine kinase activity
RT44_RS11255	COG2814	Major facilitator Superfamily
RT44_RS11270	COG1272	protein, Hemolysin III
RT44_RS11280	COG1988	membrane-bound metal-dependent
RT44_RS11290	COG3314	Sporulation integral membrane protein YlbJ
RT44_RS11295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT44_RS11300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RT44_RS11305	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RT44_RS11310	COG3457	Alanine racemase
RT44_RS11315	COG4264	IucA IucC family
RT44_RS11320	COG2814	Major facilitator Superfamily
RT44_RS11345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RT44_RS11355	COG2130	NADP-dependent
RT44_RS11420	COG0656	L-ascorbic acid biosynthetic process
RT44_RS11425	COG0789	Transcriptional regulator
RT44_RS11435	COG5492	domain, Protein
RT44_RS11485	COG3527	Alpha-acetolactate decarboxylase
RT44_RS11490	COG0028	Belongs to the TPP enzyme family
RT44_RS11505	COG0384	phenazine biosynthesis protein PhzF
RT44_RS11575	COG0201	protein transport
RT44_RS11690	COG2252	PERMEase
RT44_RS11735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RT44_RS11805	COG1763	Mo-molybdopterin cofactor biosynthetic process
RT44_RS11825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RT44_RS11830	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RT44_RS11835	COG4149	molybdate abc transporter
RT44_RS11840	COG0725	ABC transporter, periplasmic molybdate-binding protein
RT44_RS11855	COG1268	BioY protein
RT44_RS11870	COG1960	acyl-CoA dehydrogenase activity
RT44_RS11875	COG4413	Urea transporter
RT44_RS11950	COG1757	Na H antiporter
RT44_RS11965	COG3942	CHAP domain
RT44_RS12035	COG1113	amino acid transport
RT44_RS12055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RT44_RS12060	COG0385	Bile acid
RT44_RS12070	COG1263	PTS System
RT44_RS12070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RT44_RS12075	COG1737	Transcriptional regulator
RT44_RS12095	COG1028	Short-chain dehydrogenase reductase Sdr
RT44_RS12100	COG1473	amidohydrolase
RT44_RS12115	COG0583	DNA-binding transcription factor activity
RT44_RS12135	COG2258	MOSC domain
RT44_RS12155	COG1668	transmembrane transport
RT44_RS12160	COG4152	abc transporter atp-binding protein
RT44_RS12165	COG3152	Membrane
RT44_RS12175	COG0786	glutamate:sodium symporter activity
RT44_RS12185	COG0598	Magnesium transport protein CorA
RT44_RS12200	COG0657	acetylesterase activity
RT44_RS12210	COG2814	Major facilitator Superfamily
RT44_RS12215	COG1566	PFAM secretion protein HlyD family protein
RT44_RS12225	COG2814	Major facilitator Superfamily
RT44_RS12290	COG1620	l-lactate permease
RT44_RS12310	COG0604	alcohol dehydrogenase
RT44_RS12340	COG1511	domain protein
RT44_RS12355	COG1263	PTS System
RT44_RS12355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RT44_RS12370	COG3871	stress protein (general stress protein 26)
RT44_RS12420	COG2181	nitrate reductase activity
RT44_RS12430	COG1140	nitrate reductase beta subunit
RT44_RS12435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RT44_RS12445	COG2146	nitrite reductase [NAD(P)H] activity
RT44_RS12450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RT44_RS12460	COG0454	-acetyltransferase
RT44_RS12465	COG2116	formate transmembrane transporter activity
RT44_RS12480	COG3443	Belongs to the bacterial solute-binding protein 9 family
RT44_RS12480	COG0803	Belongs to the bacterial solute-binding protein 9 family
RT44_RS12515	COG1126	abc transporter atp-binding protein
RT44_RS12520	COG0765	amino acid transport
RT44_RS12525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RT44_RS12530	COG2814	Major facilitator Superfamily
RT44_RS12545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RT44_RS12590	COG0156	8-amino-7-oxononanoate synthase activity
RT44_RS12600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RT44_RS12605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RT44_RS12620	COG1132	(ABC) transporter
RT44_RS12625	COG2375	cellular response to nickel ion
RT44_RS12625	COG1132	(ABC) transporter
RT44_RS12645	COG1929	Belongs to the glycerate kinase type-1 family
RT44_RS12655	COG2814	Major facilitator Superfamily
RT44_RS12675	COG1113	amino acid transport
RT44_RS12690	COG0531	amino acid
RT44_RS12715	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RT44_RS12725	COG1174	glycine betaine transport
RT44_RS12735	COG1174	glycine betaine transport
RT44_RS12750	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
RT44_RS12755	COG0531	amino acid
RT44_RS12760	COG2272	Belongs to the type-B carboxylesterase lipase family
RT44_RS12765	COG2814	Major facilitator Superfamily
RT44_RS12770	COG0390	transport system, permease component
RT44_RS12775	COG4619	ABC transporter
RT44_RS12780	COG1363	Peptidase, m42
RT44_RS12800	COG4808	Protein conserved in bacteria
RT44_RS12805	COG0069	glutamate synthase activity
RT44_RS12820	COG1124	(ABC) transporter
RT44_RS12825	COG0444	Belongs to the ABC transporter superfamily
RT44_RS12830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RT44_RS12860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RT44_RS12870	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
RT44_RS12875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RT44_RS12925	COG0494	nUDIX hydrolase
RT44_RS12965	COG1846	Transcriptional regulator
RT44_RS13000	COG1070	Carbohydrate kinase
RT44_RS13005	COG1802	Transcriptional regulator
RT44_RS13010	COG0789	Transcriptional regulator
RT44_RS13015	COG2357	RelA SpoT domain protein
RT44_RS13020	COG4876	unkown
RT44_RS13030	COG2271	Major facilitator Superfamily
RT44_RS13035	COG0586	Pfam SNARE associated Golgi protein
RT44_RS13045	COG2814	Major facilitator Superfamily
RT44_RS13050	COG1846	Transcriptional regulator
RT44_RS13055	COG1131	(ABC) transporter
RT44_RS13075	COG3949	Membrane
RT44_RS13080	COG0400	carboxylic ester hydrolase activity
RT44_RS13090	COG1846	Transcriptional regulator
RT44_RS13100	COG2514	catechol 2,3-dioxygenase activity
RT44_RS13115	COG0561	phosphatase activity
RT44_RS13120	COG1131	(ABC) transporter
RT44_RS13130	COG3764	Sortase (surface protein transpeptidase)
RT44_RS13150	COG1760	l-serine dehydratase
RT44_RS13155	COG1760	l-serine dehydratase
RT44_RS13170	COG0697	spore germination
RT44_RS13175	COG0657	acetylesterase activity
RT44_RS13195	COG0028	Belongs to the TPP enzyme family
RT44_RS13210	COG0583	DNA-binding transcription factor activity
RT44_RS13220	COG3942	CHAP domain
RT44_RS13230	COG3425	synthase
RT44_RS13240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RT44_RS13265	COG2409	Drug exporters of the RND superfamily
RT44_RS13310	COG0436	Aminotransferase
RT44_RS13340	COG3942	CHAP domain
RT44_RS13345	COG2755	lipolytic protein G-D-S-L family
RT44_RS13345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RT44_RS13445	COG3001	Fructosamine kinase
RT44_RS13450	COG0167	dihydroorotate dehydrogenase activity
RT44_RS13500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RT44_RS13505	COG3527	Alpha-acetolactate decarboxylase
RT44_RS13520	COG0531	amino acid
RT44_RS13550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RT44_RS13570	COG1012	belongs to the aldehyde dehydrogenase family
RT44_RS13580	COG1510	regulation of RNA biosynthetic process
RT44_RS13590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RT44_RS13615	COG2851	Citrate transporter
RT44_RS13625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RT44_RS13635	COG0386	Belongs to the glutathione peroxidase family
RT44_RS13660	COG1136	(ABC) transporter
RT44_RS13665	COG2205	protein histidine kinase activity
RT44_RS13670	COG0745	RESPONSE REGULATOR receiver
RT44_RS13685	COG1785	Belongs to the alkaline phosphatase family
RT44_RS13690	COG1846	Transcriptional regulator
RT44_RS13735	COG1438	arginine binding
RT44_RS13755	COG3711	transcriptional antiterminator
RT44_RS13755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RT44_RS13760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RT44_RS13760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RT44_RS13760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RT44_RS13765	COG1482	cell wall glycoprotein biosynthetic process
RT44_RS13775	COG3942	CHAP domain
RT44_RS13775	COG1705	Flagellar rod assembly protein muramidase FlgJ
RT44_RS13780	COG1535	isochorismatase
RT44_RS13780	COG3433	isochorismatase activity
RT44_RS13795	COG0438	transferase activity, transferring glycosyl groups
RT44_RS13810	COG1073	alpha beta
RT44_RS13830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RT44_RS13850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RT44_RS13935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RT44_RS14020	COG0471	metal ion transport
RT44_RS14025	COG2962	Rard protein
RT44_RS14035	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RT44_RS14050	COG1136	(ABC) transporter
RT44_RS14055	COG0577	efflux transmembrane transporter activity
RT44_RS14065	COG1278	Cold shock
RT44_RS14085	COG1475	DNA binding