locus-tag	class	description
AS852_RS00015	COG2501	S4 domain
AS852_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AS852_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AS852_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AS852_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
AS852_RS00125	COG4863	YycH protein
AS852_RS00135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AS852_RS00140	COG0737	Belongs to the 5'-nucleotidase family
AS852_RS00165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS852_RS00165	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS852_RS00205	COG3425	synthase
AS852_RS00215	COG0584	glycerophosphoryl diester phosphodiesterase
AS852_RS00220	COG2030	dehydratase
AS852_RS00315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AS852_RS00340	COG0640	Transcriptional regulator
AS852_RS00345	COG2217	Heavy metal translocating P-type atpase
AS852_RS00350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS852_RS00355	COG2210	Belongs to the sulfur carrier protein TusA family
AS852_RS00360	COG1937	Protein conserved in bacteria
AS852_RS00365	COG0730	response to heat
AS852_RS00370	COG2217	Heavy metal translocating P-type atpase
AS852_RS00375	COG1388	LysM domain
AS852_RS00450	COG2814	Major facilitator Superfamily
AS852_RS00475	COG0456	acetyltransferase
AS852_RS00500	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS852_RS00515	COG1073	alpha beta
AS852_RS00525	COG2226	methyltransferase
AS852_RS00535	COG0823	Involved in the tonB-independent uptake of proteins
AS852_RS00550	COG1473	amidohydrolase
AS852_RS00560	COG1283	sodium-dependent phosphate transmembrane transporter activity
AS852_RS00565	COG4716	Myosin-crossreactive antigen
AS852_RS00575	COG1620	l-lactate permease
AS852_RS00595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS852_RS00600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS852_RS00605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS852_RS00615	COG2423	ornithine cyclodeaminase activity
AS852_RS00620	COG4264	IucA IucC family
AS852_RS00625	COG2814	Major facilitator Superfamily
AS852_RS00630	COG4264	IucA IucC family
AS852_RS00635	COG4264	IucA IucC family
AS852_RS00645	COG0019	diaminopimelate decarboxylase activity
AS852_RS00650	COG1475	DNA binding
AS852_RS00685	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS852_RS00690	COG0438	transferase activity, transferring glycosyl groups
AS852_RS00720	COG0813	purine-nucleoside phosphorylase activity
AS852_RS00725	COG2814	Major facilitator Superfamily
AS852_RS00745	COG3639	organic phosphonate transmembrane transporter activity
AS852_RS00765	COG0737	Belongs to the 5'-nucleotidase family
AS852_RS00780	COG1012	belongs to the aldehyde dehydrogenase family
AS852_RS00780	COG1454	alcohol dehydrogenase
AS852_RS00805	COG1086	Polysaccharide biosynthesis protein
AS852_RS00815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS852_RS00845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AS852_RS00855	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AS852_RS00860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS852_RS00870	COG2832	Protein of unknown function (DUF454)
AS852_RS00905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AS852_RS00910	COG1960	acyl-CoA dehydrogenase activity
AS852_RS00915	COG5609	conserved protein (DUF2294)
AS852_RS00970	COG1309	transcriptional regulator
AS852_RS00975	COG1114	Component of the transport system for branched-chain amino acids
AS852_RS00980	COG1335	isochorismatase
AS852_RS00985	COG3961	Belongs to the TPP enzyme family
AS852_RS01010	COG1737	Transcriptional regulator
AS852_RS01035	COG0601	transmembrane transport
AS852_RS01040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS852_RS01050	COG0405	Gamma-glutamyltransferase
AS852_RS01070	COG3842	ATPase activity
AS852_RS01080	COG1175	transmembrane transport
AS852_RS01085	COG3833	ABC-type maltose transport systems, permease component
AS852_RS01090	COG0673	inositol 2-dehydrogenase activity
AS852_RS01095	COG0673	inositol 2-dehydrogenase activity
AS852_RS01105	COG1755	Isoprenylcysteine carboxyl methyltransferase
AS852_RS01165	COG0183	Belongs to the thiolase family
AS852_RS01175	COG1960	acyl-CoA dehydrogenase activity
AS852_RS01180	COG0318	PFAM AMP-dependent synthetase and ligase
AS852_RS01200	COG0747	negative chemotaxis
AS852_RS01205	COG3189	MarR family transcriptional regulator
AS852_RS01235	COG1263	PTS System
AS852_RS01235	COG2190	(PTS) system
AS852_RS01235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS852_RS01240	COG1957	nucleoside hydrolase
AS852_RS01255	COG3414	Phosphotransferase system galactitol-specific IIB component
AS852_RS01260	COG3775	system Galactitol-specific IIC component
AS852_RS01265	COG1063	alcohol dehydrogenase
AS852_RS01275	COG1063	alcohol dehydrogenase
AS852_RS01285	COG1063	alcohol dehydrogenase
AS852_RS01290	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS852_RS01310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS852_RS01320	COG1063	alcohol dehydrogenase
AS852_RS01325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS852_RS01365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS852_RS01375	COG2190	(PTS) system
AS852_RS01375	COG1263	PTS System
AS852_RS01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS852_RS01380	COG2723	6-phospho-beta-galactosidase activity
AS852_RS01390	COG2226	methyltransferase
AS852_RS01445	COG1131	(ABC) transporter
AS852_RS01465	COG3942	CHAP domain
AS852_RS01465	COG1388	LysM domain
AS852_RS01575	COG1114	Component of the transport system for branched-chain amino acids
AS852_RS01585	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AS852_RS01595	COG0577	efflux transmembrane transporter activity
AS852_RS01620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS852_RS01625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AS852_RS01650	COG3314	Sporulation integral membrane protein YlbJ
AS852_RS01675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS852_RS01705	COG3037	sugar-specific permease SgaT UlaA
AS852_RS01715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS852_RS01720	COG3711	transcriptional antiterminator
AS852_RS01745	COG2271	Major facilitator Superfamily
AS852_RS01750	COG0346	lactoylglutathione lyase activity
AS852_RS01755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS852_RS01760	COG0431	NADPH-dependent FMN reductase
AS852_RS01775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS852_RS01780	COG2822	iron ion transport
AS852_RS01790	COG0672	)-iron permease
AS852_RS01795	COG0805	protein transport
AS852_RS01800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AS852_RS01810	COG1476	TRANSCRIPTIONal
AS852_RS01820	COG1131	(ABC) transporter
AS852_RS01855	COG0646	methionine synthase
AS852_RS01855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AS852_RS01860	COG0626	cystathionine gamma-synthase activity
AS852_RS01865	COG0626	cystathionine gamma-synthase activity
AS852_RS01875	COG1475	DNA binding
AS852_RS01880	COG0668	transmembrane transport
AS852_RS01885	COG4481	Protein conserved in bacteria
AS852_RS01890	COG0012	GTP binding
AS852_RS01990	COG1823	symporter activity
AS852_RS02025	COG2233	PERMEase
AS852_RS02065	COG3759	membrane
AS852_RS02205	COG0523	cobalamin synthesis protein
AS852_RS02220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AS852_RS02230	COG5609	conserved protein (DUF2294)
AS852_RS02245	COG1647	Serine aminopeptidase, S33
AS852_RS02250	COG0733	neurotransmitter:sodium symporter activity
AS852_RS02255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AS852_RS02260	COG0626	cystathionine gamma-synthase activity
AS852_RS02270	COG2011	ABC-type metal ion transport system permease component
AS852_RS02275	COG1464	Belongs to the NlpA lipoprotein family
AS852_RS02310	COG0583	DNA-binding transcription factor activity
AS852_RS02315	COG0069	glutamate synthase activity
AS852_RS02315	COG0067	glutamate synthase
AS852_RS02315	COG0070	glutamate synthase
AS852_RS02320	COG0493	'glutamate synthase
AS852_RS02330	COG1263	PTS System
AS852_RS02330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS852_RS02335	COG0366	Alpha amylase catalytic
AS852_RS02340	COG2188	Transcriptional regulator
AS852_RS02360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AS852_RS02395	COG1982	Orn Lys Arg decarboxylase major
AS852_RS02405	COG3870	Protein conserved in bacteria
AS852_RS02415	COG0470	DNA polymerase III
AS852_RS02420	COG1774	PSP1 C-terminal conserved region
AS852_RS02430	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AS852_RS02440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AS852_RS02455	COG0084	hydrolase, TatD family'
AS852_RS02460	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS852_RS02470	COG4466	Protein conserved in bacteria
AS852_RS02480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AS852_RS02485	COG0251	oxidation-reduction process
AS852_RS02530	COG2244	polysaccharide biosynthetic process
AS852_RS02535	COG3956	TIGRFAM MazG family protein
AS852_RS02540	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AS852_RS02550	COG1098	S1 RNA binding domain
AS852_RS02565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AS852_RS02590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS852_RS02685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AS852_RS02705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS852_RS02715	COG3880	PFAM UvrB UvrC protein
AS852_RS02735	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AS852_RS02740	COG4956	integral membrane protein (PIN domain superfamily)
AS852_RS02765	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AS852_RS02820	COG2813	Specifically methylates the guanine in position
AS852_RS02860	COG1473	amidohydrolase
AS852_RS02890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AS852_RS02895	COG1428	Deoxynucleoside kinase
AS852_RS02900	COG1428	Deoxynucleoside kinase
AS852_RS02910	COG0561	phosphatase activity
AS852_RS02955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AS852_RS03070	COG0095	Lipoate-protein ligase
AS852_RS03075	COG0083	homoserine kinase activity
AS852_RS03095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS852_RS03175	COG0667	Aldo Keto reductase
AS852_RS03190	COG0655	NAD(P)H dehydrogenase (quinone) activity
AS852_RS03200	COG1078	dGTPase activity
AS852_RS03235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AS852_RS03240	COG4139	cobalamin transport
AS852_RS03335	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS852_RS03340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS852_RS03345	COG1121	(ABC) transporter
AS852_RS03350	COG1321	iron dependent repressor
AS852_RS03360	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AS852_RS03370	COG1682	transport, permease protein
AS852_RS03375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AS852_RS03385	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AS852_RS03390	COG1686	Belongs to the peptidase S11 family
AS852_RS03395	COG1132	(ABC) transporter
AS852_RS03400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AS852_RS03410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AS852_RS03415	COG1120	ATPase activity
AS852_RS03420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS852_RS03425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS852_RS03430	COG2376	Dihydroxyacetone kinase
AS852_RS03450	COG3949	Membrane
AS852_RS03475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AS852_RS03490	COG1136	(ABC) transporter
AS852_RS03495	COG0577	efflux transmembrane transporter activity
AS852_RS03500	COG1392	Phosphate transport regulator
AS852_RS03505	COG0306	phosphate transporter
AS852_RS03510	COG1388	LysM domain
AS852_RS03510	COG3942	CHAP domain
AS852_RS03520	COG1917	Cupin 2, conserved barrel domain protein
AS852_RS03520	COG4977	sequence-specific DNA binding
AS852_RS03550	COG0583	DNA-binding transcription factor activity
AS852_RS03560	COG2814	Major facilitator Superfamily
AS852_RS03565	COG2839	Protein conserved in bacteria
AS852_RS03595	COG1611	Belongs to the LOG family
AS852_RS03615	COG4988	ABC transporter
AS852_RS03620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AS852_RS03630	COG0523	cobalamin synthesis protein
AS852_RS03635	COG4989	oxidoreductase activity
AS852_RS03645	COG0471	metal ion transport
AS852_RS03650	COG0415	Belongs to the DNA photolyase family
AS852_RS03680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AS852_RS03685	COG1349	DNA-binding transcription factor activity
AS852_RS03690	COG1105	Belongs to the carbohydrate kinase PfkB family
AS852_RS03695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS852_RS03695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS852_RS03695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS852_RS03705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AS852_RS03710	COG1253	flavin adenine dinucleotide binding
AS852_RS03715	COG0656	L-ascorbic acid biosynthetic process
AS852_RS03720	COG0463	Glycosyl transferase, family 2
AS852_RS03755	COG0720	synthase
AS852_RS03765	COG0512	Glutamine amidotransferase of anthranilate synthase
AS852_RS03765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AS852_RS03770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS852_RS03805	COG0488	(ABC) transporter
AS852_RS03810	COG0514	ATP-dependent DNA helicase (RecQ)
AS852_RS03815	COG1125	glycine betaine transport
AS852_RS03815	COG0517	IMP dehydrogenase activity
AS852_RS03820	COG1174	glycine betaine transport
AS852_RS03855	COG3104	oligopeptide transport
AS852_RS03885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS852_RS03890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AS852_RS03900	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS852_RS03905	COG4605	iron ion homeostasis
AS852_RS03910	COG4604	ABC transporter, ATP-binding protein
AS852_RS03915	COG4607	ABC-type enterochelin transport system periplasmic component
AS852_RS03975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AS852_RS03980	COG1739	Uncharacterized protein family UPF0029
AS852_RS03990	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AS852_RS03995	COG1040	competence protein
AS852_RS04030	COG1388	LysM domain
AS852_RS04030	COG3942	CHAP domain
AS852_RS04100	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AS852_RS04120	COG0281	malic enzyme
AS852_RS04175	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AS852_RS04180	COG1647	Serine aminopeptidase, S33
AS852_RS04185	COG0557	exoribonuclease II activity
AS852_RS04250	COG1278	Cold shock
AS852_RS04290	COG0406	alpha-ribazole phosphatase activity
AS852_RS04295	COG1279	arginine transmembrane transporter activity
AS852_RS04320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS852_RS04325	COG1393	Belongs to the ArsC family
AS852_RS04340	COG3878	Protein conserved in bacteria
AS852_RS04355	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AS852_RS04370	COG2011	ABC-type metal ion transport system permease component
AS852_RS04375	COG1464	Belongs to the NlpA lipoprotein family
AS852_RS04395	COG0396	ATPase activity
AS852_RS04400	COG0719	Fe-S assembly protein
AS852_RS04410	COG0822	iron-sulfur transferase activity
AS852_RS04430	COG1253	flavin adenine dinucleotide binding
AS852_RS04440	COG1801	Protein of unknown function DUF72
AS852_RS04445	COG0730	response to heat
AS852_RS04460	COG4470	Protein conserved in bacteria
AS852_RS04470	COG2445	Protein of unknown function DUF86
AS852_RS04500	COG1696	Membrane protein involved in D-alanine export
AS852_RS04510	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AS852_RS04515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AS852_RS04520	COG4837	Protein of unknown function (DUF1462)
AS852_RS04525	COG1252	NADH dehydrogenase
AS852_RS04535	COG0316	Belongs to the HesB IscA family
AS852_RS04545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AS852_RS04550	COG2056	Na+-H+ antiporter family
AS852_RS04555	COG2050	protein possibly involved in aromatic compounds catabolism
AS852_RS04610	COG1098	S1 RNA binding domain
AS852_RS04615	COG1902	pentaerythritol trinitrate reductase activity
AS852_RS04645	COG0584	glycerophosphoryl diester phosphodiesterase
AS852_RS04665	COG0398	Pfam SNARE associated Golgi protein
AS852_RS04750	COG0741	lytic transglycosylase activity
AS852_RS04750	COG0791	NLP P60 protein
AS852_RS04780	COG2946	Replication initiation factor
AS852_RS04790	COG1674	ftsk spoiiie
AS852_RS04815	COG0561	phosphatase activity
AS852_RS04845	COG1881	PFAM PEBP family protein
AS852_RS04875	COG0601	transmembrane transport
AS852_RS04880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS852_RS04885	COG0444	Belongs to the ABC transporter superfamily
AS852_RS04890	COG4608	Belongs to the ABC transporter superfamily
AS852_RS04895	COG4166	transmembrane transport
AS852_RS04900	COG0601	transmembrane transport
AS852_RS04905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS852_RS04910	COG0444	Belongs to the ABC transporter superfamily
AS852_RS04915	COG4608	Belongs to the ABC transporter superfamily
AS852_RS04920	COG4166	transmembrane transport
AS852_RS04945	COG1164	Oligoendopeptidase f
AS852_RS04955	COG2346	COG2346, Truncated hemoglobins
AS852_RS04970	COG2357	RelA SpoT domain protein
AS852_RS04980	COG0564	pseudouridine synthase activity
AS852_RS04985	COG2239	Acts as a magnesium transporter
AS852_RS04990	COG0569	domain protein
AS852_RS04990	COG0475	glutathione-regulated potassium exporter activity
AS852_RS05000	COG0628	permease
AS852_RS05005	COG1115	amino acid carrier protein
AS852_RS05045	COG0861	Integral membrane protein TerC family
AS852_RS05055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS852_RS05060	COG0737	Belongs to the 5'-nucleotidase family
AS852_RS05075	COG4903	ComK protein
AS852_RS05090	COG4873	Protein conserved in bacteria
AS852_RS05140	COG3682	Transcriptional regulator
AS852_RS05170	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS852_RS05180	COG2314	TM2 domain
AS852_RS05185	COG0456	acetyltransferase
AS852_RS05190	COG1575	Belongs to the MenA family. Type 1 subfamily
AS852_RS05195	COG1169	isochorismate synthase
AS852_RS05235	COG0436	Aminotransferase
AS852_RS05240	COG3594	Acyltransferase
AS852_RS05270	COG1316	TRANSCRIPTIONal
AS852_RS05315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AS852_RS05330	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AS852_RS05375	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AS852_RS05380	COG4172	Belongs to the ABC transporter superfamily
AS852_RS05385	COG4721	ABC-type cobalt transport system, permease component
AS852_RS05405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AS852_RS05430	COG1271	oxidase subunit
AS852_RS05435	COG1294	oxidase, subunit
AS852_RS05440	COG0569	domain protein
AS852_RS05510	COG1176	ABC-type spermidine putrescine transport system, permease component I
AS852_RS05515	COG1177	transmembrane transport
AS852_RS05520	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AS852_RS05545	COG0483	inositol monophosphate 1-phosphatase activity
AS852_RS05555	COG1217	gtp-binding protein TYPA
AS852_RS05565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AS852_RS05575	COG0772	Belongs to the SEDS family
AS852_RS05610	COG3679	Belongs to the UPF0342 family
AS852_RS05615	COG0584	glycerophosphoryl diester phosphodiesterase
AS852_RS05630	COG0742	ribosomal rna small subunit methyltransferase
AS852_RS05690	COG4509	Sortase family
AS852_RS05705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AS852_RS05740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AS852_RS05740	COG1796	DNA polymerase
AS852_RS05765	COG2009	succinate dehydrogenase
AS852_RS05770	COG1053	succinate dehydrogenase
AS852_RS05775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AS852_RS05895	COG1288	antiporter activity
AS852_RS05930	COG1011	Hydrolase
AS852_RS05955	COG4839	cell division protein FtsL
AS852_RS05960	COG0768	penicillin binding
AS852_RS05975	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AS852_RS05980	COG0849	cell division
AS852_RS05995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AS852_RS06005	COG0762	integral membrane protein
AS852_RS06010	COG2302	S4 RNA-binding domain
AS852_RS06015	COG3599	regulation of cell shape
AS852_RS06025	COG2826	transposase and inactivated derivatives, IS30 family
AS852_RS06030	COG2514	catechol 2,3-dioxygenase activity
AS852_RS06040	COG0564	pseudouridine synthase activity
AS852_RS06050	COG2233	PERMEase
AS852_RS06095	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AS852_RS06110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AS852_RS06115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AS852_RS06125	COG2314	TM2 domain
AS852_RS06140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AS852_RS06140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AS852_RS06150	COG0631	protein serine/threonine phosphatase activity
AS852_RS06165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AS852_RS06180	COG1302	Protein conserved in bacteria
AS852_RS06230	COG1196	nuclear chromosome segregation
AS852_RS06235	COG0552	protein localization to endoplasmic reticulum
AS852_RS06245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS852_RS06310	COG0758	DNA mediated transformation
AS852_RS06410	COG0195	Participates in both transcription termination and antitermination
AS852_RS06415	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AS852_RS06440	COG0196	riboflavin kinase activity
AS852_RS06470	COG2188	Transcriptional regulator
AS852_RS06475	COG0612	Peptidase, M16
AS852_RS06480	COG0612	Peptidase, M16
AS852_RS06485	COG0300	oxidoreductase activity
AS852_RS06505	COG1546	Belongs to the CinA family
AS852_RS06505	COG1058	Belongs to the CinA family
AS852_RS06525	COG1692	metallophosphoesterase
AS852_RS06530	COG0674	pyruvate-flavodoxin oxidoreductase activity
AS852_RS06530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AS852_RS06535	COG1013	pyruvate-flavodoxin oxidoreductase activity
AS852_RS06540	COG2826	transposase and inactivated derivatives, IS30 family
AS852_RS06575	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AS852_RS06580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AS852_RS06605	COG1923	regulation of RNA biosynthetic process
AS852_RS06615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AS852_RS06620	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AS852_RS06625	COG0789	Transcriptional regulator
AS852_RS06715	COG1525	nuclease
AS852_RS06730	COG0527	aspartate kinase activity
AS852_RS06735	COG0460	homoserine dehydrogenase
AS852_RS06740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AS852_RS06765	COG0833	amino acid
AS852_RS06795	COG2340	Cysteine-rich secretory protein family
AS852_RS06830	COG4846	Membrane protein involved in cytochrome C biogenesis
AS852_RS06850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS852_RS06870	COG0824	Thioesterase
AS852_RS06900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AS852_RS06910	COG1115	amino acid carrier protein
AS852_RS06925	COG0628	permease
AS852_RS06950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AS852_RS06960	COG1363	Peptidase, m42
AS852_RS06965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AS852_RS06970	COG0512	Glutamine amidotransferase of anthranilate synthase
AS852_RS07010	COG0561	phosphatase activity
AS852_RS07060	COG0704	Plays a role in the regulation of phosphate uptake
AS852_RS07070	COG0581	inorganic phosphate transmembrane transporter activity
AS852_RS07075	COG0573	inorganic phosphate transmembrane transporter activity
AS852_RS07095	COG0488	(ABC) transporter
AS852_RS07100	COG0527	aspartate kinase activity
AS852_RS07105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AS852_RS07140	COG2808	Putative FMN-binding domain
AS852_RS07185	COG4548	von Willebrand factor, type A
AS852_RS07190	COG0714	Associated with various cellular activities
AS852_RS07235	COG0671	phosphoesterase, PA-phosphatase related
AS852_RS07315	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AS852_RS07335	COG0531	amino acid
AS852_RS07350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS852_RS07355	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AS852_RS07370	COG0116	Belongs to the methyltransferase superfamily
AS852_RS07410	COG4499	WXG100 protein secretion system (Wss), protein YukC
AS852_RS07410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AS852_RS07420	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AS852_RS07425	COG3935	DnaD domain protein
AS852_RS07450	COG0438	transferase activity, transferring glycosyl groups
AS852_RS07455	COG1694	Mazg nucleotide pyrophosphohydrolase
AS852_RS07460	COG2738	Putative neutral zinc metallopeptidase
AS852_RS07465	COG4347	Protein of unknown function (DUF1405)
AS852_RS07505	COG0142	geranyltranstransferase activity
AS852_RS07570	COG0492	ferredoxin-NADP+ reductase activity
AS852_RS07585	COG0514	ATP-dependent DNA helicase (RecQ)
AS852_RS07595	COG1141	Ferredoxin
AS852_RS07635	COG1388	LysM domain
AS852_RS07635	COG0860	N-Acetylmuramoyl-L-alanine amidase
AS852_RS07685	COG3953	SLT domain
AS852_RS07685	COG5280	Phage tail tape measure protein TP901
AS852_RS07970	COG0582	viral genome integration into host DNA
AS852_RS07990	COG5002	protein histidine kinase activity
AS852_RS07995	COG0745	RESPONSE REGULATOR receiver
AS852_RS08000	COG1187	pseudouridine synthase activity
AS852_RS08025	COG0735	belongs to the Fur family
AS852_RS08030	COG0494	nUDIX hydrolase
AS852_RS08035	COG0667	Aldo Keto reductase
AS852_RS08060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AS852_RS08070	COG0366	Alpha amylase catalytic
AS852_RS08075	COG1609	Transcriptional regulator
AS852_RS08095	COG2195	Cleaves the N-terminal amino acid of tripeptides
AS852_RS08105	COG4129	membrane
AS852_RS08115	COG0508	dehydrogenase complex catalyzes the overall conversion of
AS852_RS08120	COG0022	dehydrogenase e1 component
AS852_RS08125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AS852_RS08130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AS852_RS08135	COG0497	DNA recombination
AS852_RS08165	COG1302	Protein conserved in bacteria
AS852_RS08170	COG0439	Biotin carboxylase
AS852_RS08175	COG0511	ligase activity, forming carbon-carbon bonds
AS852_RS08185	COG0006	proline dipeptidase activity
AS852_RS08200	COG0095	Lipoate-protein ligase
AS852_RS08205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AS852_RS08250	COG4537	Required for transformation and DNA binding
AS852_RS08255	COG1459	type II secretion system
AS852_RS08260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AS852_RS08265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS852_RS08270	COG0011	TIGRFAM Protein of
AS852_RS08275	COG1940	carbohydrate kinase activity
AS852_RS08280	COG4483	Protein conserved in bacteria
AS852_RS08290	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AS852_RS08300	COG0768	penicillin binding
AS852_RS08315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AS852_RS08320	COG1121	(ABC) transporter
AS852_RS08330	COG0513	Belongs to the DEAD box helicase family
AS852_RS08340	COG2384	SAM-dependent methyltransferase
AS852_RS08360	COG0517	IMP dehydrogenase activity
AS852_RS08380	COG0295	cytidine deaminase activity
AS852_RS08395	COG1702	phosphate starvation-inducible protein PhoH
AS852_RS08410	COG1030	water channel activity
AS852_RS08420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AS852_RS08425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AS852_RS08455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AS852_RS08475	COG1466	dna polymerase III delta subunit
AS852_RS08480	COG0658	competence protein
AS852_RS08480	COG2333	competence protein COMEC
AS852_RS08485	COG2131	deaminase
AS852_RS08495	COG2226	methyltransferase
AS852_RS08500	COG0799	negative regulation of ribosome biogenesis
AS852_RS08505	COG1713	HD superfamily hydrolase involved in NAD metabolism
AS852_RS08515	COG1534	Rna-binding protein
AS852_RS08525	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AS852_RS08530	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AS852_RS08550	COG3177	Filamentation induced by cAMP protein fic
AS852_RS08555	COG1914	H( )-stimulated, divalent metal cation uptake system
AS852_RS08565	COG0439	Biotin carboxylase
AS852_RS08570	COG0511	ligase activity, forming carbon-carbon bonds
AS852_RS08575	COG1984	allophanate hydrolase subunit 2
AS852_RS08580	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AS852_RS08595	COG0826	peptidase U32
AS852_RS08600	COG0826	peptidase U32
AS852_RS08630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AS852_RS08655	COG1104	cysteine desulfurase activity
AS852_RS08660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AS852_RS08670	COG3237	CsbD-like
AS852_RS08675	COG1959	2 iron, 2 sulfur cluster binding
AS852_RS08685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AS852_RS08690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AS852_RS08735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AS852_RS08735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AS852_RS08740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS852_RS08740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AS852_RS08745	COG1862	Preprotein translocase
AS852_RS08785	COG2868	ribosomal protein
AS852_RS08830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AS852_RS08865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AS852_RS08875	COG0285	dihydrofolate synthase activity
AS852_RS08885	COG2818	Glycosylase
AS852_RS08920	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AS852_RS08955	COG4112	unkown
AS852_RS08980	COG0833	amino acid
AS852_RS08995	COG1484	DNA-dependent DNA replication
AS852_RS09025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS852_RS09025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AS852_RS09035	COG5002	protein histidine kinase activity
AS852_RS09040	COG0745	RESPONSE REGULATOR receiver
AS852_RS09055	COG0372	Belongs to the citrate synthase family
AS852_RS09060	COG1113	amino acid transport
AS852_RS09085	COG0281	malic enzyme
AS852_RS09095	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AS852_RS09105	COG4109	DRTGG domain
AS852_RS09150	COG0827	DNA restriction-modification system
AS852_RS09160	COG0730	response to heat
AS852_RS09170	COG1104	cysteine desulfurase activity
AS852_RS09180	COG1956	GAF domain-containing protein
AS852_RS09195	COG0584	glycerophosphoryl diester phosphodiesterase
AS852_RS09200	COG1764	response to oxidative stress
AS852_RS09205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AS852_RS09210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS852_RS09225	COG1263	PTS System
AS852_RS09225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS852_RS09230	COG0204	Acyl-transferase
AS852_RS09235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AS852_RS09255	COG5386	Cell surface protein
AS852_RS09270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS852_RS09275	COG0454	-acetyltransferase
AS852_RS09295	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AS852_RS09295	COG1605	Chorismate mutase
AS852_RS09320	COG1674	ftsk spoiiie
AS852_RS09325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AS852_RS09335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AS852_RS09340	COG1363	Peptidase, m42
AS852_RS09350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AS852_RS09360	COG0510	thiamine kinase activity
AS852_RS09380	COG1187	pseudouridine synthase activity
AS852_RS09385	COG2244	polysaccharide biosynthetic process
AS852_RS09390	COG2081	HI0933 family
AS852_RS09410	COG2814	Major facilitator Superfamily
AS852_RS09415	COG1242	4 iron, 4 sulfur cluster binding
AS852_RS09420	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AS852_RS09430	COG2267	carboxylic ester hydrolase activity
AS852_RS09465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS852_RS09465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AS852_RS09485	COG3266	domain, Protein
AS852_RS09485	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS852_RS09485	COG4193	domain, Protein
AS852_RS09525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AS852_RS09545	COG0656	L-ascorbic acid biosynthetic process
AS852_RS09565	COG1506	peptidase
AS852_RS09570	COG2816	NAD+ diphosphatase activity
AS852_RS09590	COG2826	transposase and inactivated derivatives, IS30 family
AS852_RS09665	COG5492	domain, Protein
AS852_RS09725	COG1388	LysM domain
AS852_RS09725	COG5632	N-Acetylmuramoyl-L-alanine amidase
AS852_RS09960	COG0305	Participates in initiation and elongation during chromosome replication
AS852_RS10105	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AS852_RS10135	COG1131	(ABC) transporter
AS852_RS10140	COG0537	adenosine 5'-monophosphoramidase activity
AS852_RS10170	COG0420	3'-5' exonuclease activity
AS852_RS10200	COG2197	response regulator
AS852_RS10205	COG4585	Histidine kinase
AS852_RS10205	COG2203	Gaf domain
AS852_RS10210	COG0564	pseudouridine synthase activity
AS852_RS10245	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AS852_RS10250	COG1126	abc transporter atp-binding protein
AS852_RS10255	COG0765	amino acid transport
AS852_RS10420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AS852_RS10425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS852_RS10435	COG4129	membrane
AS852_RS10455	COG1194	a g-specific adenine glycosylase
AS852_RS10460	COG1988	membrane-bound metal-dependent
AS852_RS10475	COG1134	teichoic acid transport
AS852_RS10475	COG1388	LysM domain
AS852_RS10505	COG0535	radical SAM domain protein
AS852_RS10510	COG1607	acyl-coa hydrolase
AS852_RS10515	COG2309	aminopeptidase activity
AS852_RS10535	COG1295	ribonuclease BN
AS852_RS10660	COG4851	CamS sex pheromone cAM373 precursor
AS852_RS10680	COG4496	protein, YerC YecD
AS852_RS10715	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AS852_RS10725	COG0077	Prephenate dehydratase
AS852_RS10740	COG1335	isochorismatase
AS852_RS10755	COG1012	belongs to the aldehyde dehydrogenase family
AS852_RS10805	COG1131	(ABC) transporter
AS852_RS10820	COG1725	Transcriptional regulator
AS852_RS10870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AS852_RS10945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AS852_RS10950	COG1621	beta-fructofuranosidase activity
AS852_RS10955	COG1609	Transcriptional regulator
AS852_RS10960	COG0004	ammonium transporteR
AS852_RS10965	COG0425	Belongs to the sulfur carrier protein TusA family
AS852_RS10970	COG2391	methyltransferase activity
AS852_RS10980	COG0488	(ABC) transporter
AS852_RS10990	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AS852_RS11005	COG0456	acetyltransferase
AS852_RS11010	COG1214	PFAM Peptidase M22, glycoprotease
AS852_RS11015	COG0802	atpase or kinase
AS852_RS11030	COG0028	Belongs to the TPP enzyme family
AS852_RS11105	COG2183	response to ionizing radiation
AS852_RS11110	COG1191	sigma factor activity
AS852_RS11120	COG1366	Belongs to the anti-sigma-factor antagonist family
AS852_RS11125	COG2208	phosphoserine phosphatase activity
AS852_RS11160	COG3428	Bacterial PH domain
AS852_RS11190	COG2205	protein histidine kinase activity
AS852_RS11195	COG0745	RESPONSE REGULATOR receiver
AS852_RS11205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AS852_RS11215	COG0772	Belongs to the SEDS family
AS852_RS11230	COG1937	Protein conserved in bacteria
AS852_RS11240	COG1418	mRNA catabolic process
AS852_RS11295	COG0629	single-stranded DNA binding
AS852_RS11375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AS852_RS11400	COG0009	L-threonylcarbamoyladenylate synthase
AS852_RS11405	COG2890	protein-(glutamine-N5) methyltransferase activity
AS852_RS11430	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AS852_RS11470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AS852_RS11525	COG0813	purine-nucleoside phosphorylase activity
AS852_RS11530	COG0783	Belongs to the Dps family
AS852_RS11550	COG1482	cell wall glycoprotein biosynthetic process
AS852_RS11555	COG0702	epimerase
AS852_RS11560	COG0640	Transcriptional regulator
AS852_RS11600	COG0561	phosphatase activity
AS852_RS11605	COG1119	ATPase activity
AS852_RS11625	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AS852_RS11695	COG3711	transcriptional antiterminator
AS852_RS11725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AS852_RS11785	COG0489	protein tyrosine kinase activity
AS852_RS11790	COG2814	Major facilitator Superfamily
AS852_RS11805	COG1272	protein, Hemolysin III
AS852_RS11815	COG1988	membrane-bound metal-dependent
AS852_RS11825	COG3314	Sporulation integral membrane protein YlbJ
AS852_RS11830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS852_RS11835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AS852_RS11840	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AS852_RS11850	COG3457	Alanine racemase
AS852_RS11855	COG4264	IucA IucC family
AS852_RS11860	COG2814	Major facilitator Superfamily
AS852_RS11885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS852_RS11895	COG2130	NADP-dependent
AS852_RS11960	COG0656	L-ascorbic acid biosynthetic process
AS852_RS11965	COG0789	Transcriptional regulator
AS852_RS11975	COG5492	domain, Protein
AS852_RS11990	COG0438	transferase activity, transferring glycosyl groups
AS852_RS12005	COG3527	Alpha-acetolactate decarboxylase
AS852_RS12010	COG0028	Belongs to the TPP enzyme family
AS852_RS12015	COG2826	transposase and inactivated derivatives, IS30 family
AS852_RS12090	COG0201	protein transport
AS852_RS12205	COG2252	PERMEase
AS852_RS12250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AS852_RS12325	COG1763	Mo-molybdopterin cofactor biosynthetic process
AS852_RS12345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AS852_RS12350	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AS852_RS12355	COG4149	molybdate abc transporter
AS852_RS12360	COG0725	ABC transporter, periplasmic molybdate-binding protein
AS852_RS12375	COG1268	BioY protein
AS852_RS12390	COG1960	acyl-CoA dehydrogenase activity
AS852_RS12395	COG4413	Urea transporter
AS852_RS12470	COG1757	Na H antiporter
AS852_RS12485	COG3942	CHAP domain
AS852_RS12550	COG1266	CAAX protease self-immunity
AS852_RS12565	COG1113	amino acid transport
AS852_RS12585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AS852_RS12590	COG0385	Bile acid
AS852_RS12600	COG1263	PTS System
AS852_RS12600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS852_RS12605	COG1737	Transcriptional regulator
AS852_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
AS852_RS12630	COG1473	amidohydrolase
AS852_RS12645	COG0583	DNA-binding transcription factor activity
AS852_RS12665	COG2258	MOSC domain
AS852_RS12680	COG1668	transmembrane transport
AS852_RS12685	COG4152	abc transporter atp-binding protein
AS852_RS12690	COG3152	Membrane
AS852_RS12705	COG0786	glutamate:sodium symporter activity
AS852_RS12715	COG0598	Magnesium transport protein CorA
AS852_RS12730	COG0657	acetylesterase activity
AS852_RS12740	COG2814	Major facilitator Superfamily
AS852_RS12745	COG1566	PFAM secretion protein HlyD family protein
AS852_RS12755	COG2814	Major facilitator Superfamily
AS852_RS12820	COG1620	l-lactate permease
AS852_RS12830	COG2826	transposase and inactivated derivatives, IS30 family
AS852_RS12845	COG0604	alcohol dehydrogenase
AS852_RS12875	COG1511	domain protein
AS852_RS12890	COG1263	PTS System
AS852_RS12890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AS852_RS12905	COG3871	stress protein (general stress protein 26)
AS852_RS12950	COG0789	Transcriptional regulator
AS852_RS12970	COG2181	nitrate reductase activity
AS852_RS12980	COG1140	nitrate reductase beta subunit
AS852_RS12985	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AS852_RS12995	COG2146	nitrite reductase [NAD(P)H] activity
AS852_RS13000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AS852_RS13010	COG0454	-acetyltransferase
AS852_RS13020	COG2116	formate transmembrane transporter activity
AS852_RS13035	COG3443	Belongs to the bacterial solute-binding protein 9 family
AS852_RS13035	COG0803	Belongs to the bacterial solute-binding protein 9 family
AS852_RS13060	COG1126	abc transporter atp-binding protein
AS852_RS13065	COG0765	amino acid transport
AS852_RS13070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AS852_RS13075	COG2814	Major facilitator Superfamily
AS852_RS13090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AS852_RS13140	COG0156	8-amino-7-oxononanoate synthase activity
AS852_RS13150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AS852_RS13155	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AS852_RS13170	COG1132	(ABC) transporter
AS852_RS13175	COG2375	cellular response to nickel ion
AS852_RS13175	COG1132	(ABC) transporter
AS852_RS13195	COG1929	Belongs to the glycerate kinase type-1 family
AS852_RS13205	COG2814	Major facilitator Superfamily
AS852_RS13225	COG1113	amino acid transport
AS852_RS13235	COG0531	amino acid
AS852_RS13260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS852_RS13270	COG1174	glycine betaine transport
AS852_RS13280	COG1174	glycine betaine transport
AS852_RS13295	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AS852_RS13300	COG0531	amino acid
AS852_RS13305	COG2272	Belongs to the type-B carboxylesterase lipase family
AS852_RS13310	COG2814	Major facilitator Superfamily
AS852_RS13315	COG0390	transport system, permease component
AS852_RS13320	COG4619	ABC transporter
AS852_RS13325	COG1363	Peptidase, m42
AS852_RS13330	COG4808	Protein conserved in bacteria
AS852_RS13335	COG0069	glutamate synthase activity
AS852_RS13350	COG1124	(ABC) transporter
AS852_RS13360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AS852_RS13365	COG0601	transmembrane transport
AS852_RS13370	COG0747	negative chemotaxis
AS852_RS13400	COG1028	Short-chain dehydrogenase reductase Sdr
AS852_RS13405	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AS852_RS13410	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AS852_RS13565	COG1070	Carbohydrate kinase
AS852_RS13570	COG1802	Transcriptional regulator
AS852_RS13575	COG0789	Transcriptional regulator
AS852_RS13580	COG2357	RelA SpoT domain protein
AS852_RS13585	COG4876	unkown
AS852_RS13600	COG2271	Major facilitator Superfamily
AS852_RS13605	COG0586	Pfam SNARE associated Golgi protein
AS852_RS13615	COG2814	Major facilitator Superfamily
AS852_RS13620	COG1846	Transcriptional regulator
AS852_RS13630	COG1131	(ABC) transporter
AS852_RS13650	COG3949	Membrane
AS852_RS13655	COG0400	carboxylic ester hydrolase activity
AS852_RS13660	COG0346	lactoylglutathione lyase activity
AS852_RS13665	COG1846	Transcriptional regulator
AS852_RS13675	COG2514	catechol 2,3-dioxygenase activity
AS852_RS13690	COG0561	phosphatase activity
AS852_RS13695	COG3764	Sortase (surface protein transpeptidase)
AS852_RS13715	COG1760	l-serine dehydratase
AS852_RS13720	COG1760	l-serine dehydratase
AS852_RS13735	COG0697	spore germination
AS852_RS13740	COG0657	acetylesterase activity
AS852_RS13760	COG0028	Belongs to the TPP enzyme family
AS852_RS13775	COG0583	DNA-binding transcription factor activity
AS852_RS13785	COG3942	CHAP domain
AS852_RS13795	COG3425	synthase
AS852_RS13800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AS852_RS13825	COG2409	Drug exporters of the RND superfamily
AS852_RS13870	COG0436	Aminotransferase
AS852_RS13975	COG0596	Alpha beta hydrolase
AS852_RS14015	COG3001	Fructosamine kinase
AS852_RS14020	COG0167	dihydroorotate dehydrogenase activity
AS852_RS14070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AS852_RS14075	COG3527	Alpha-acetolactate decarboxylase
AS852_RS14090	COG0531	amino acid
AS852_RS14120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AS852_RS14140	COG1012	belongs to the aldehyde dehydrogenase family
AS852_RS14150	COG1510	regulation of RNA biosynthetic process
AS852_RS14155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AS852_RS14180	COG2851	Citrate transporter
AS852_RS14195	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AS852_RS14205	COG0386	Belongs to the glutathione peroxidase family
AS852_RS14230	COG1136	(ABC) transporter
AS852_RS14235	COG2205	protein histidine kinase activity
AS852_RS14240	COG0745	RESPONSE REGULATOR receiver
AS852_RS14255	COG1785	Belongs to the alkaline phosphatase family
AS852_RS14265	COG1846	Transcriptional regulator
AS852_RS14310	COG1438	arginine binding
AS852_RS14330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS852_RS14330	COG3711	transcriptional antiterminator
AS852_RS14335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AS852_RS14335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS852_RS14335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AS852_RS14340	COG1482	cell wall glycoprotein biosynthetic process
AS852_RS14350	COG1705	Flagellar rod assembly protein muramidase FlgJ
AS852_RS14350	COG3942	CHAP domain
AS852_RS14355	COG3433	isochorismatase activity
AS852_RS14355	COG1535	isochorismatase
AS852_RS14370	COG0438	transferase activity, transferring glycosyl groups
AS852_RS14385	COG1073	alpha beta
AS852_RS14405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS852_RS14435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AS852_RS14535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AS852_RS14605	COG0471	metal ion transport
AS852_RS14615	COG2962	Rard protein
AS852_RS14625	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AS852_RS14640	COG1136	(ABC) transporter
AS852_RS14645	COG0577	efflux transmembrane transporter activity
AS852_RS14655	COG1278	Cold shock
AS852_RS14675	COG1475	DNA binding