locus-tag	class	description
SAS_RS00015	COG2501	S4 domain
SAS_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SAS_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SAS_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SAS_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SAS_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
SAS_RS00110	COG4863	YycH protein
SAS_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SAS_RS00125	COG0737	Belongs to the 5'-nucleotidase family
SAS_RS00250	COG0456	acetyltransferase
SAS_RS00265	COG0730	response to heat
SAS_RS00270	COG1937	Protein conserved in bacteria
SAS_RS00275	COG2210	Belongs to the sulfur carrier protein TusA family
SAS_RS00280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAS_RS00315	COG0655	NAD(P)H dehydrogenase (quinone) activity
SAS_RS00330	COG0583	DNA-binding transcription factor activity
SAS_RS00390	COG1473	amidohydrolase
SAS_RS00400	COG1283	sodium-dependent phosphate transmembrane transporter activity
SAS_RS00405	COG4716	Myosin-crossreactive antigen
SAS_RS00415	COG1620	l-lactate permease
SAS_RS00430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAS_RS00435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAS_RS00440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAS_RS00450	COG2423	ornithine cyclodeaminase activity
SAS_RS00455	COG4264	IucA IucC family
SAS_RS00460	COG2814	Major facilitator Superfamily
SAS_RS00465	COG4264	IucA IucC family
SAS_RS00470	COG4264	IucA IucC family
SAS_RS00480	COG0019	diaminopimelate decarboxylase activity
SAS_RS00485	COG1475	DNA binding
SAS_RS00515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAS_RS00520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAS_RS00525	COG0438	transferase activity, transferring glycosyl groups
SAS_RS00560	COG0813	purine-nucleoside phosphorylase activity
SAS_RS00565	COG2814	Major facilitator Superfamily
SAS_RS00585	COG3639	organic phosphonate transmembrane transporter activity
SAS_RS00605	COG0737	Belongs to the 5'-nucleotidase family
SAS_RS00635	COG1454	alcohol dehydrogenase
SAS_RS00635	COG1012	belongs to the aldehyde dehydrogenase family
SAS_RS00660	COG1086	Polysaccharide biosynthesis protein
SAS_RS00670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAS_RS00700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAS_RS00710	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SAS_RS00715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAS_RS00725	COG2832	Protein of unknown function (DUF454)
SAS_RS00760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SAS_RS00765	COG1960	acyl-CoA dehydrogenase activity
SAS_RS00770	COG5609	conserved protein (DUF2294)
SAS_RS00820	COG1114	Component of the transport system for branched-chain amino acids
SAS_RS00825	COG1335	isochorismatase
SAS_RS00830	COG3961	Belongs to the TPP enzyme family
SAS_RS00860	COG1737	Transcriptional regulator
SAS_RS00885	COG1136	(ABC) transporter
SAS_RS00890	COG0577	efflux transmembrane transporter activity
SAS_RS00890	COG1136	(ABC) transporter
SAS_RS00910	COG1131	(ABC) transporter
SAS_RS00925	COG0601	transmembrane transport
SAS_RS00930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAS_RS00940	COG0405	Gamma-glutamyltransferase
SAS_RS00960	COG3842	ATPase activity
SAS_RS00970	COG1175	transmembrane transport
SAS_RS00975	COG3833	ABC-type maltose transport systems, permease component
SAS_RS00980	COG0673	inositol 2-dehydrogenase activity
SAS_RS00985	COG0673	inositol 2-dehydrogenase activity
SAS_RS00995	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAS_RS01060	COG0183	Belongs to the thiolase family
SAS_RS01070	COG1960	acyl-CoA dehydrogenase activity
SAS_RS01075	COG0318	PFAM AMP-dependent synthetase and ligase
SAS_RS01090	COG0747	negative chemotaxis
SAS_RS01095	COG3189	MarR family transcriptional regulator
SAS_RS01125	COG1263	PTS System
SAS_RS01125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAS_RS01125	COG2190	(PTS) system
SAS_RS01130	COG1957	nucleoside hydrolase
SAS_RS01145	COG3414	Phosphotransferase system galactitol-specific IIB component
SAS_RS01150	COG3775	system Galactitol-specific IIC component
SAS_RS01155	COG1063	alcohol dehydrogenase
SAS_RS01165	COG1063	alcohol dehydrogenase
SAS_RS01175	COG1063	alcohol dehydrogenase
SAS_RS01180	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAS_RS01190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAS_RS01200	COG1063	alcohol dehydrogenase
SAS_RS01205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAS_RS01240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAS_RS01245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAS_RS01245	COG1263	PTS System
SAS_RS01245	COG2190	(PTS) system
SAS_RS01250	COG2723	6-phospho-beta-galactosidase activity
SAS_RS01255	COG2226	methyltransferase
SAS_RS01310	COG1131	(ABC) transporter
SAS_RS01330	COG3942	CHAP domain
SAS_RS01330	COG1388	LysM domain
SAS_RS01460	COG1114	Component of the transport system for branched-chain amino acids
SAS_RS01465	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SAS_RS01475	COG0577	efflux transmembrane transporter activity
SAS_RS01500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAS_RS01505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SAS_RS01530	COG3314	Sporulation integral membrane protein YlbJ
SAS_RS01555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAS_RS01585	COG3037	sugar-specific permease SgaT UlaA
SAS_RS01595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAS_RS01600	COG3711	transcriptional antiterminator
SAS_RS01620	COG2271	Major facilitator Superfamily
SAS_RS01625	COG0346	lactoylglutathione lyase activity
SAS_RS01630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAS_RS01635	COG0431	NADPH-dependent FMN reductase
SAS_RS01645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAS_RS01660	COG0672	)-iron permease
SAS_RS01665	COG0805	protein transport
SAS_RS01670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SAS_RS01680	COG1476	TRANSCRIPTIONal
SAS_RS01690	COG1131	(ABC) transporter
SAS_RS01725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SAS_RS01725	COG0646	methionine synthase
SAS_RS01730	COG0626	cystathionine gamma-synthase activity
SAS_RS01735	COG0626	cystathionine gamma-synthase activity
SAS_RS01740	COG1475	DNA binding
SAS_RS01745	COG0668	transmembrane transport
SAS_RS01750	COG4481	Protein conserved in bacteria
SAS_RS01755	COG0012	GTP binding
SAS_RS01855	COG1823	symporter activity
SAS_RS01885	COG2233	PERMEase
SAS_RS01960	COG1683	Conserved Protein
SAS_RS01970	COG3759	membrane
SAS_RS02115	COG0523	cobalamin synthesis protein
SAS_RS02125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SAS_RS02135	COG5609	conserved protein (DUF2294)
SAS_RS02150	COG1647	Serine aminopeptidase, S33
SAS_RS02160	COG0733	neurotransmitter:sodium symporter activity
SAS_RS02165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAS_RS02170	COG0626	cystathionine gamma-synthase activity
SAS_RS02180	COG2011	ABC-type metal ion transport system permease component
SAS_RS02185	COG1464	Belongs to the NlpA lipoprotein family
SAS_RS02220	COG0583	DNA-binding transcription factor activity
SAS_RS02225	COG0067	glutamate synthase
SAS_RS02225	COG0070	glutamate synthase
SAS_RS02225	COG0069	glutamate synthase activity
SAS_RS02230	COG0493	'glutamate synthase
SAS_RS02240	COG1263	PTS System
SAS_RS02240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAS_RS02245	COG0366	Alpha amylase catalytic
SAS_RS02250	COG2188	Transcriptional regulator
SAS_RS02265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAS_RS02300	COG1982	Orn Lys Arg decarboxylase major
SAS_RS02310	COG3870	Protein conserved in bacteria
SAS_RS02320	COG0470	DNA polymerase III
SAS_RS02325	COG1774	PSP1 C-terminal conserved region
SAS_RS02335	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SAS_RS02345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SAS_RS02360	COG0084	hydrolase, TatD family'
SAS_RS02365	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAS_RS02375	COG4466	Protein conserved in bacteria
SAS_RS02385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAS_RS02390	COG0251	oxidation-reduction process
SAS_RS02435	COG2244	polysaccharide biosynthetic process
SAS_RS02440	COG3956	TIGRFAM MazG family protein
SAS_RS02445	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SAS_RS02455	COG1098	S1 RNA binding domain
SAS_RS02470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAS_RS02495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SAS_RS02590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAS_RS02605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAS_RS02615	COG3880	PFAM UvrB UvrC protein
SAS_RS02635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SAS_RS02640	COG4956	integral membrane protein (PIN domain superfamily)
SAS_RS02660	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SAS_RS02710	COG2813	Specifically methylates the guanine in position
SAS_RS02750	COG1473	amidohydrolase
SAS_RS02780	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SAS_RS02785	COG1428	Deoxynucleoside kinase
SAS_RS02790	COG1428	Deoxynucleoside kinase
SAS_RS02800	COG0561	phosphatase activity
SAS_RS02840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SAS_RS02945	COG0095	Lipoate-protein ligase
SAS_RS02950	COG0083	homoserine kinase activity
SAS_RS02970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAS_RS03055	COG0667	Aldo Keto reductase
SAS_RS03060	COG0655	NAD(P)H dehydrogenase (quinone) activity
SAS_RS03070	COG1078	dGTPase activity
SAS_RS03105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAS_RS03110	COG4139	cobalamin transport
SAS_RS03160	COG4974	Belongs to the 'phage' integrase family
SAS_RS03205	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAS_RS03210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAS_RS03215	COG1121	(ABC) transporter
SAS_RS03220	COG1321	iron dependent repressor
SAS_RS03230	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SAS_RS03240	COG1682	transport, permease protein
SAS_RS03245	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAS_RS03255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SAS_RS03260	COG1686	Belongs to the peptidase S11 family
SAS_RS03265	COG1132	(ABC) transporter
SAS_RS03270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAS_RS03280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAS_RS03285	COG1120	ATPase activity
SAS_RS03290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAS_RS03295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAS_RS03300	COG2376	Dihydroxyacetone kinase
SAS_RS03310	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SAS_RS03320	COG3949	Membrane
SAS_RS03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAS_RS03360	COG1136	(ABC) transporter
SAS_RS03365	COG0577	efflux transmembrane transporter activity
SAS_RS03370	COG1392	Phosphate transport regulator
SAS_RS03375	COG0306	phosphate transporter
SAS_RS03380	COG1388	LysM domain
SAS_RS03380	COG3942	CHAP domain
SAS_RS03390	COG1917	Cupin 2, conserved barrel domain protein
SAS_RS03390	COG4977	sequence-specific DNA binding
SAS_RS03420	COG0583	DNA-binding transcription factor activity
SAS_RS03430	COG2814	Major facilitator Superfamily
SAS_RS03435	COG2839	Protein conserved in bacteria
SAS_RS03465	COG1611	Belongs to the LOG family
SAS_RS03485	COG4988	ABC transporter
SAS_RS03490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAS_RS03505	COG4989	oxidoreductase activity
SAS_RS03515	COG0471	metal ion transport
SAS_RS03520	COG0415	Belongs to the DNA photolyase family
SAS_RS03550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAS_RS03555	COG1349	DNA-binding transcription factor activity
SAS_RS03560	COG1105	Belongs to the carbohydrate kinase PfkB family
SAS_RS03565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAS_RS03565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAS_RS03565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAS_RS03575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SAS_RS03580	COG1253	flavin adenine dinucleotide binding
SAS_RS03585	COG0656	L-ascorbic acid biosynthetic process
SAS_RS03590	COG0463	Glycosyl transferase, family 2
SAS_RS03625	COG0720	synthase
SAS_RS03635	COG0512	Glutamine amidotransferase of anthranilate synthase
SAS_RS03635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SAS_RS03640	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAS_RS03675	COG0488	(ABC) transporter
SAS_RS03680	COG0514	ATP-dependent DNA helicase (RecQ)
SAS_RS03685	COG1125	glycine betaine transport
SAS_RS03685	COG0517	IMP dehydrogenase activity
SAS_RS03690	COG1174	glycine betaine transport
SAS_RS03720	COG3104	oligopeptide transport
SAS_RS03740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAS_RS03745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAS_RS03760	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAS_RS03765	COG4605	iron ion homeostasis
SAS_RS03770	COG4604	ABC transporter, ATP-binding protein
SAS_RS03775	COG4607	ABC-type enterochelin transport system periplasmic component
SAS_RS03830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAS_RS03835	COG1739	Uncharacterized protein family UPF0029
SAS_RS03845	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SAS_RS03850	COG1040	competence protein
SAS_RS03880	COG3942	CHAP domain
SAS_RS03880	COG1388	LysM domain
SAS_RS03940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SAS_RS04005	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SAS_RS04010	COG1647	Serine aminopeptidase, S33
SAS_RS04015	COG0557	exoribonuclease II activity
SAS_RS04070	COG1278	Cold shock
SAS_RS04110	COG0406	alpha-ribazole phosphatase activity
SAS_RS04115	COG1279	arginine transmembrane transporter activity
SAS_RS04140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAS_RS04145	COG1393	Belongs to the ArsC family
SAS_RS04160	COG3878	Protein conserved in bacteria
SAS_RS04165	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAS_RS04180	COG2011	ABC-type metal ion transport system permease component
SAS_RS04185	COG1464	Belongs to the NlpA lipoprotein family
SAS_RS04200	COG0396	ATPase activity
SAS_RS04205	COG0719	Fe-S assembly protein
SAS_RS04215	COG0822	iron-sulfur transferase activity
SAS_RS04235	COG1253	flavin adenine dinucleotide binding
SAS_RS04245	COG1801	Protein of unknown function DUF72
SAS_RS04250	COG0730	response to heat
SAS_RS04265	COG4470	Protein conserved in bacteria
SAS_RS04275	COG2445	Protein of unknown function DUF86
SAS_RS04305	COG1696	Membrane protein involved in D-alanine export
SAS_RS04315	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SAS_RS04320	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SAS_RS04325	COG4837	Protein of unknown function (DUF1462)
SAS_RS04330	COG1252	NADH dehydrogenase
SAS_RS04340	COG0316	Belongs to the HesB IscA family
SAS_RS04350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SAS_RS04355	COG2056	Na+-H+ antiporter family
SAS_RS04360	COG2050	protein possibly involved in aromatic compounds catabolism
SAS_RS04415	COG1098	S1 RNA binding domain
SAS_RS04420	COG1902	pentaerythritol trinitrate reductase activity
SAS_RS04435	COG0584	glycerophosphoryl diester phosphodiesterase
SAS_RS04455	COG0398	Pfam SNARE associated Golgi protein
SAS_RS04495	COG0561	phosphatase activity
SAS_RS04520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SAS_RS04535	COG1881	PFAM PEBP family protein
SAS_RS04565	COG0601	transmembrane transport
SAS_RS04570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAS_RS04575	COG0444	Belongs to the ABC transporter superfamily
SAS_RS04580	COG4608	Belongs to the ABC transporter superfamily
SAS_RS04585	COG4166	transmembrane transport
SAS_RS04590	COG0747	negative chemotaxis
SAS_RS04595	COG0444	Belongs to the ABC transporter superfamily
SAS_RS04600	COG4608	Belongs to the ABC transporter superfamily
SAS_RS04605	COG0601	transmembrane transport
SAS_RS04610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAS_RS04635	COG1164	Oligoendopeptidase f
SAS_RS04645	COG2346	COG2346, Truncated hemoglobins
SAS_RS04660	COG2357	RelA SpoT domain protein
SAS_RS04670	COG0564	pseudouridine synthase activity
SAS_RS04675	COG2239	Acts as a magnesium transporter
SAS_RS04680	COG0475	glutathione-regulated potassium exporter activity
SAS_RS04680	COG0569	domain protein
SAS_RS04690	COG0628	permease
SAS_RS04695	COG1115	amino acid carrier protein
SAS_RS04735	COG0861	Integral membrane protein TerC family
SAS_RS04740	COG0582	viral genome integration into host DNA
SAS_RS04995	COG5280	Phage tail tape measure protein TP901
SAS_RS04995	COG3953	SLT domain
SAS_RS05045	COG1388	LysM domain
SAS_RS05045	COG0860	N-Acetylmuramoyl-L-alanine amidase
SAS_RS05055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAS_RS05060	COG0737	Belongs to the 5'-nucleotidase family
SAS_RS05075	COG4903	ComK protein
SAS_RS05090	COG4873	Protein conserved in bacteria
SAS_RS05150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAS_RS05160	COG2314	TM2 domain
SAS_RS05165	COG0456	acetyltransferase
SAS_RS05170	COG1575	Belongs to the MenA family. Type 1 subfamily
SAS_RS05175	COG1169	isochorismate synthase
SAS_RS05185	COG2267	carboxylic ester hydrolase activity
SAS_RS05210	COG0436	Aminotransferase
SAS_RS05215	COG3594	Acyltransferase
SAS_RS05245	COG1316	TRANSCRIPTIONal
SAS_RS05290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SAS_RS05305	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAS_RS05335	COG0138	bifunctional purine biosynthesis protein purh
SAS_RS05345	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SAS_RS05350	COG4172	Belongs to the ABC transporter superfamily
SAS_RS05355	COG4721	ABC-type cobalt transport system, permease component
SAS_RS05375	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAS_RS05395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SAS_RS05400	COG1271	oxidase subunit
SAS_RS05405	COG1294	oxidase, subunit
SAS_RS05410	COG0569	domain protein
SAS_RS05480	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAS_RS05485	COG1177	transmembrane transport
SAS_RS05490	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SAS_RS05515	COG0483	inositol monophosphate 1-phosphatase activity
SAS_RS05525	COG1217	gtp-binding protein TYPA
SAS_RS05535	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SAS_RS05545	COG0772	Belongs to the SEDS family
SAS_RS05580	COG3679	Belongs to the UPF0342 family
SAS_RS05600	COG0742	ribosomal rna small subunit methyltransferase
SAS_RS05660	COG4509	Sortase family
SAS_RS05675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAS_RS05705	COG1796	DNA polymerase
SAS_RS05705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SAS_RS05730	COG2009	succinate dehydrogenase
SAS_RS05735	COG1053	succinate dehydrogenase
SAS_RS05740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SAS_RS05865	COG1288	antiporter activity
SAS_RS05900	COG1011	Hydrolase
SAS_RS05925	COG4839	cell division protein FtsL
SAS_RS05930	COG0768	penicillin binding
SAS_RS05945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SAS_RS05965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAS_RS05975	COG0762	integral membrane protein
SAS_RS05980	COG2302	S4 RNA-binding domain
SAS_RS05985	COG3599	regulation of cell shape
SAS_RS05995	COG2514	catechol 2,3-dioxygenase activity
SAS_RS06010	COG0564	pseudouridine synthase activity
SAS_RS06020	COG2233	PERMEase
SAS_RS06065	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SAS_RS06080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SAS_RS06085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SAS_RS06095	COG2314	TM2 domain
SAS_RS06110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAS_RS06110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAS_RS06120	COG0631	protein serine/threonine phosphatase activity
SAS_RS06135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SAS_RS06150	COG1302	Protein conserved in bacteria
SAS_RS06200	COG1196	nuclear chromosome segregation
SAS_RS06205	COG0552	protein localization to endoplasmic reticulum
SAS_RS06215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SAS_RS06280	COG0758	DNA mediated transformation
SAS_RS06375	COG0195	Participates in both transcription termination and antitermination
SAS_RS06380	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SAS_RS06405	COG0196	riboflavin kinase activity
SAS_RS06430	COG2188	Transcriptional regulator
SAS_RS06435	COG0612	Peptidase, M16
SAS_RS06440	COG0612	Peptidase, M16
SAS_RS06445	COG0300	oxidoreductase activity
SAS_RS06465	COG1546	Belongs to the CinA family
SAS_RS06465	COG1058	Belongs to the CinA family
SAS_RS06485	COG1692	metallophosphoesterase
SAS_RS06490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SAS_RS06490	COG0674	pyruvate-flavodoxin oxidoreductase activity
SAS_RS06495	COG1013	pyruvate-flavodoxin oxidoreductase activity
SAS_RS06530	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SAS_RS06535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAS_RS06560	COG1923	regulation of RNA biosynthetic process
SAS_RS06570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAS_RS06575	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SAS_RS06580	COG0789	Transcriptional regulator
SAS_RS06675	COG1131	(ABC) transporter
SAS_RS06690	COG2197	response regulator
SAS_RS06700	COG1525	nuclease
SAS_RS06715	COG0527	aspartate kinase activity
SAS_RS06720	COG0460	homoserine dehydrogenase
SAS_RS06725	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SAS_RS06750	COG0833	amino acid
SAS_RS06780	COG2340	Cysteine-rich secretory protein family
SAS_RS06815	COG4846	Membrane protein involved in cytochrome C biogenesis
SAS_RS06835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAS_RS06845	COG0824	Thioesterase
SAS_RS06875	COG1115	amino acid carrier protein
SAS_RS06890	COG0628	permease
SAS_RS06915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SAS_RS06925	COG1363	Peptidase, m42
SAS_RS06930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAS_RS06935	COG0512	Glutamine amidotransferase of anthranilate synthase
SAS_RS07025	COG0704	Plays a role in the regulation of phosphate uptake
SAS_RS07035	COG0581	inorganic phosphate transmembrane transporter activity
SAS_RS07040	COG0573	inorganic phosphate transmembrane transporter activity
SAS_RS07065	COG0488	(ABC) transporter
SAS_RS07070	COG0527	aspartate kinase activity
SAS_RS07075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SAS_RS07160	COG4548	von Willebrand factor, type A
SAS_RS07165	COG0714	Associated with various cellular activities
SAS_RS07205	COG0671	phosphoesterase, PA-phosphatase related
SAS_RS07290	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SAS_RS07320	COG0531	amino acid
SAS_RS07335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAS_RS07340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SAS_RS07365	COG0116	Belongs to the methyltransferase superfamily
SAS_RS07395	COG4499	WXG100 protein secretion system (Wss), protein YukC
SAS_RS07395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAS_RS07405	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SAS_RS07410	COG3935	DnaD domain protein
SAS_RS07435	COG0438	transferase activity, transferring glycosyl groups
SAS_RS07440	COG1694	Mazg nucleotide pyrophosphohydrolase
SAS_RS07445	COG2738	Putative neutral zinc metallopeptidase
SAS_RS07450	COG4347	Protein of unknown function (DUF1405)
SAS_RS07490	COG0142	geranyltranstransferase activity
SAS_RS07545	COG0492	ferredoxin-NADP+ reductase activity
SAS_RS07560	COG0514	ATP-dependent DNA helicase (RecQ)
SAS_RS07570	COG1141	Ferredoxin
SAS_RS07610	COG5002	protein histidine kinase activity
SAS_RS07615	COG0745	RESPONSE REGULATOR receiver
SAS_RS07620	COG1187	pseudouridine synthase activity
SAS_RS07645	COG0735	belongs to the Fur family
SAS_RS07650	COG0494	nUDIX hydrolase
SAS_RS07655	COG0667	Aldo Keto reductase
SAS_RS07665	COG4221	oxidoreductase activity
SAS_RS07680	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SAS_RS07690	COG0366	Alpha amylase catalytic
SAS_RS07695	COG1609	Transcriptional regulator
SAS_RS07715	COG2195	Cleaves the N-terminal amino acid of tripeptides
SAS_RS07725	COG4129	membrane
SAS_RS07735	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAS_RS07740	COG0022	dehydrogenase e1 component
SAS_RS07745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SAS_RS07750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAS_RS07755	COG0497	DNA recombination
SAS_RS07785	COG1302	Protein conserved in bacteria
SAS_RS07790	COG0439	Biotin carboxylase
SAS_RS07795	COG0511	ligase activity, forming carbon-carbon bonds
SAS_RS07805	COG0006	proline dipeptidase activity
SAS_RS07820	COG0095	Lipoate-protein ligase
SAS_RS07825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAS_RS07870	COG4537	Required for transformation and DNA binding
SAS_RS07875	COG1459	type II secretion system
SAS_RS07880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SAS_RS07885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAS_RS07890	COG0011	TIGRFAM Protein of
SAS_RS07895	COG1940	carbohydrate kinase activity
SAS_RS07900	COG4483	Protein conserved in bacteria
SAS_RS07910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAS_RS07920	COG0768	penicillin binding
SAS_RS07935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAS_RS07940	COG1121	(ABC) transporter
SAS_RS07950	COG0513	Belongs to the DEAD box helicase family
SAS_RS07960	COG2384	SAM-dependent methyltransferase
SAS_RS07980	COG0517	IMP dehydrogenase activity
SAS_RS08000	COG0295	cytidine deaminase activity
SAS_RS08015	COG1702	phosphate starvation-inducible protein PhoH
SAS_RS08030	COG1030	water channel activity
SAS_RS08040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SAS_RS08045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SAS_RS08075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAS_RS08090	COG1466	dna polymerase III delta subunit
SAS_RS08095	COG0658	competence protein
SAS_RS08095	COG2333	competence protein COMEC
SAS_RS08100	COG2131	deaminase
SAS_RS08105	COG2183	response to ionizing radiation
SAS_RS08110	COG2226	methyltransferase
SAS_RS08115	COG0799	negative regulation of ribosome biogenesis
SAS_RS08120	COG1713	HD superfamily hydrolase involved in NAD metabolism
SAS_RS08130	COG1534	Rna-binding protein
SAS_RS08140	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAS_RS08145	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SAS_RS08170	COG3177	Filamentation induced by cAMP protein fic
SAS_RS08175	COG1914	H( )-stimulated, divalent metal cation uptake system
SAS_RS08185	COG0439	Biotin carboxylase
SAS_RS08190	COG0511	ligase activity, forming carbon-carbon bonds
SAS_RS08195	COG1984	allophanate hydrolase subunit 2
SAS_RS08200	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SAS_RS08215	COG0826	peptidase U32
SAS_RS08220	COG0826	peptidase U32
SAS_RS08250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAS_RS08270	COG1104	cysteine desulfurase activity
SAS_RS08275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAS_RS08285	COG3237	CsbD-like
SAS_RS08290	COG1959	2 iron, 2 sulfur cluster binding
SAS_RS08295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SAS_RS08300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SAS_RS08340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SAS_RS08340	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SAS_RS08345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAS_RS08345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAS_RS08350	COG1862	Preprotein translocase
SAS_RS08390	COG2868	ribosomal protein
SAS_RS08430	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SAS_RS08440	COG0285	dihydrofolate synthase activity
SAS_RS08450	COG2818	Glycosylase
SAS_RS08485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SAS_RS08520	COG4112	unkown
SAS_RS08545	COG0833	amino acid
SAS_RS08560	COG1484	DNA-dependent DNA replication
SAS_RS08590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAS_RS08590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAS_RS08600	COG5002	protein histidine kinase activity
SAS_RS08605	COG0745	RESPONSE REGULATOR receiver
SAS_RS08620	COG0372	Belongs to the citrate synthase family
SAS_RS08625	COG1113	amino acid transport
SAS_RS08650	COG0281	malic enzyme
SAS_RS08660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SAS_RS08670	COG4109	DRTGG domain
SAS_RS08710	COG0827	DNA restriction-modification system
SAS_RS08720	COG0730	response to heat
SAS_RS08730	COG1104	cysteine desulfurase activity
SAS_RS08745	COG1956	GAF domain-containing protein
SAS_RS08760	COG0584	glycerophosphoryl diester phosphodiesterase
SAS_RS08765	COG1764	response to oxidative stress
SAS_RS08770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SAS_RS08775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAS_RS08790	COG1263	PTS System
SAS_RS08790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAS_RS08795	COG0204	Acyl-transferase
SAS_RS08800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAS_RS08835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAS_RS08840	COG0454	-acetyltransferase
SAS_RS08860	COG1605	Chorismate mutase
SAS_RS08860	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SAS_RS08885	COG1674	ftsk spoiiie
SAS_RS08890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAS_RS08900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAS_RS08905	COG1363	Peptidase, m42
SAS_RS08915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAS_RS08925	COG0510	thiamine kinase activity
SAS_RS08945	COG1187	pseudouridine synthase activity
SAS_RS08950	COG2244	polysaccharide biosynthetic process
SAS_RS08955	COG2081	HI0933 family
SAS_RS08975	COG2814	Major facilitator Superfamily
SAS_RS08980	COG1242	4 iron, 4 sulfur cluster binding
SAS_RS08985	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SAS_RS08995	COG2267	carboxylic ester hydrolase activity
SAS_RS09025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAS_RS09025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAS_RS09045	COG3266	domain, Protein
SAS_RS09045	COG4193	domain, Protein
SAS_RS09045	COG5632	N-Acetylmuramoyl-L-alanine amidase
SAS_RS09075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SAS_RS09095	COG0656	L-ascorbic acid biosynthetic process
SAS_RS09115	COG1506	peptidase
SAS_RS09120	COG2816	NAD+ diphosphatase activity
SAS_RS09270	COG1131	(ABC) transporter
SAS_RS09375	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SAS_RS09405	COG1131	(ABC) transporter
SAS_RS09410	COG0537	adenosine 5'-monophosphoramidase activity
SAS_RS09440	COG0420	3'-5' exonuclease activity
SAS_RS09465	COG2197	response regulator
SAS_RS09470	COG2203	Gaf domain
SAS_RS09470	COG4585	Histidine kinase
SAS_RS09475	COG0564	pseudouridine synthase activity
SAS_RS09510	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SAS_RS09515	COG1126	abc transporter atp-binding protein
SAS_RS09520	COG0765	amino acid transport
SAS_RS09685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAS_RS09690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SAS_RS09700	COG4129	membrane
SAS_RS09725	COG1988	membrane-bound metal-dependent
SAS_RS09740	COG1134	teichoic acid transport
SAS_RS09740	COG1388	LysM domain
SAS_RS09770	COG0535	radical SAM domain protein
SAS_RS09775	COG1607	acyl-coa hydrolase
SAS_RS09780	COG2309	aminopeptidase activity
SAS_RS09800	COG1295	ribonuclease BN
SAS_RS09920	COG4851	CamS sex pheromone cAM373 precursor
SAS_RS09930	COG0210	DNA helicase
SAS_RS09940	COG4496	protein, YerC YecD
SAS_RS09975	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SAS_RS09985	COG0077	Prephenate dehydratase
SAS_RS10005	COG1335	isochorismatase
SAS_RS10020	COG1012	belongs to the aldehyde dehydrogenase family
SAS_RS10070	COG1131	(ABC) transporter
SAS_RS10085	COG1725	Transcriptional regulator
SAS_RS10140	COG1388	LysM domain
SAS_RS10140	COG0860	N-Acetylmuramoyl-L-alanine amidase
SAS_RS10150	COG5632	N-Acetylmuramoyl-L-alanine amidase
SAS_RS10150	COG1388	LysM domain
SAS_RS10200	COG0739	heme binding
SAS_RS10255	COG4695	Portal protein
SAS_RS10450	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SAS_RS10455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAS_RS10460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAS_RS10475	COG3728	DNA packaging
SAS_RS10475	COG5484	DNA packaging
SAS_RS10550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAS_RS10555	COG1621	beta-fructofuranosidase activity
SAS_RS10560	COG1609	Transcriptional regulator
SAS_RS10565	COG0004	ammonium transporteR
SAS_RS10570	COG0425	Belongs to the sulfur carrier protein TusA family
SAS_RS10575	COG2391	methyltransferase activity
SAS_RS10585	COG0488	(ABC) transporter
SAS_RS10595	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SAS_RS10605	COG0456	acetyltransferase
SAS_RS10610	COG1214	PFAM Peptidase M22, glycoprotease
SAS_RS10615	COG0802	atpase or kinase
SAS_RS10630	COG0028	Belongs to the TPP enzyme family
SAS_RS10700	COG2183	response to ionizing radiation
SAS_RS10705	COG1191	sigma factor activity
SAS_RS10715	COG1366	Belongs to the anti-sigma-factor antagonist family
SAS_RS10720	COG2208	phosphoserine phosphatase activity
SAS_RS10755	COG3428	Bacterial PH domain
SAS_RS10785	COG2205	protein histidine kinase activity
SAS_RS10790	COG0745	RESPONSE REGULATOR receiver
SAS_RS10800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAS_RS10810	COG0772	Belongs to the SEDS family
SAS_RS10825	COG1937	Protein conserved in bacteria
SAS_RS10835	COG1418	mRNA catabolic process
SAS_RS10880	COG0629	single-stranded DNA binding
SAS_RS10955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAS_RS10980	COG0009	L-threonylcarbamoyladenylate synthase
SAS_RS10985	COG2890	protein-(glutamine-N5) methyltransferase activity
SAS_RS11005	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SAS_RS11045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAS_RS11095	COG0813	purine-nucleoside phosphorylase activity
SAS_RS11100	COG0783	Belongs to the Dps family
SAS_RS11120	COG1482	cell wall glycoprotein biosynthetic process
SAS_RS11125	COG0702	epimerase
SAS_RS11130	COG0640	Transcriptional regulator
SAS_RS11150	COG0561	phosphatase activity
SAS_RS11155	COG1119	ATPase activity
SAS_RS11170	COG3711	transcriptional antiterminator
SAS_RS11200	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SAS_RS11260	COG0489	protein tyrosine kinase activity
SAS_RS11265	COG2814	Major facilitator Superfamily
SAS_RS11280	COG1272	protein, Hemolysin III
SAS_RS11290	COG1988	membrane-bound metal-dependent
SAS_RS11300	COG3314	Sporulation integral membrane protein YlbJ
SAS_RS11305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAS_RS11310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAS_RS11315	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAS_RS11325	COG3457	Alanine racemase
SAS_RS11330	COG4264	IucA IucC family
SAS_RS11335	COG2814	Major facilitator Superfamily
SAS_RS11360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAS_RS11370	COG2130	NADP-dependent
SAS_RS11440	COG0656	L-ascorbic acid biosynthetic process
SAS_RS11445	COG0789	Transcriptional regulator
SAS_RS11455	COG5492	domain, Protein
SAS_RS11465	COG3527	Alpha-acetolactate decarboxylase
SAS_RS11470	COG0028	Belongs to the TPP enzyme family
SAS_RS11545	COG0201	protein transport
SAS_RS11660	COG2252	PERMEase
SAS_RS11705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SAS_RS11770	COG1763	Mo-molybdopterin cofactor biosynthetic process
SAS_RS11790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SAS_RS11795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SAS_RS11800	COG4149	molybdate abc transporter
SAS_RS11805	COG0725	ABC transporter, periplasmic molybdate-binding protein
SAS_RS11820	COG1268	BioY protein
SAS_RS11835	COG1960	acyl-CoA dehydrogenase activity
SAS_RS11840	COG4413	Urea transporter
SAS_RS11915	COG1757	Na H antiporter
SAS_RS11930	COG3942	CHAP domain
SAS_RS12005	COG1113	amino acid transport
SAS_RS12025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAS_RS12030	COG0385	Bile acid
SAS_RS12040	COG1263	PTS System
SAS_RS12040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAS_RS12045	COG1737	Transcriptional regulator
SAS_RS12065	COG1028	Short-chain dehydrogenase reductase Sdr
SAS_RS12070	COG1473	amidohydrolase
SAS_RS12085	COG0583	DNA-binding transcription factor activity
SAS_RS12105	COG2258	MOSC domain
SAS_RS12125	COG1668	transmembrane transport
SAS_RS12130	COG4152	abc transporter atp-binding protein
SAS_RS12135	COG3152	Membrane
SAS_RS12145	COG0786	glutamate:sodium symporter activity
SAS_RS12155	COG0598	Magnesium transport protein CorA
SAS_RS12170	COG0657	acetylesterase activity
SAS_RS12180	COG2814	Major facilitator Superfamily
SAS_RS12185	COG1566	PFAM secretion protein HlyD family protein
SAS_RS12195	COG2814	Major facilitator Superfamily
SAS_RS12260	COG1620	l-lactate permease
SAS_RS12280	COG0604	alcohol dehydrogenase
SAS_RS12315	COG1511	domain protein
SAS_RS12330	COG1263	PTS System
SAS_RS12330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAS_RS12345	COG3871	stress protein (general stress protein 26)
SAS_RS12385	COG0789	Transcriptional regulator
SAS_RS12405	COG2181	nitrate reductase activity
SAS_RS12415	COG1140	nitrate reductase beta subunit
SAS_RS12420	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SAS_RS12430	COG2146	nitrite reductase [NAD(P)H] activity
SAS_RS12435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SAS_RS12445	COG0454	-acetyltransferase
SAS_RS12450	COG2116	formate transmembrane transporter activity
SAS_RS12465	COG3443	Belongs to the bacterial solute-binding protein 9 family
SAS_RS12465	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAS_RS12500	COG1126	abc transporter atp-binding protein
SAS_RS12505	COG0765	amino acid transport
SAS_RS12510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAS_RS12515	COG2814	Major facilitator Superfamily
SAS_RS12535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SAS_RS12580	COG0156	8-amino-7-oxononanoate synthase activity
SAS_RS12590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SAS_RS12595	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SAS_RS12610	COG1132	(ABC) transporter
SAS_RS12615	COG2375	cellular response to nickel ion
SAS_RS12615	COG1132	(ABC) transporter
SAS_RS12635	COG1929	Belongs to the glycerate kinase type-1 family
SAS_RS12645	COG2814	Major facilitator Superfamily
SAS_RS12665	COG1113	amino acid transport
SAS_RS12680	COG0531	amino acid
SAS_RS12705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAS_RS12715	COG1174	glycine betaine transport
SAS_RS12725	COG1174	glycine betaine transport
SAS_RS12745	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SAS_RS12750	COG0531	amino acid
SAS_RS12755	COG2272	Belongs to the type-B carboxylesterase lipase family
SAS_RS12760	COG2814	Major facilitator Superfamily
SAS_RS12765	COG0390	transport system, permease component
SAS_RS12770	COG4619	ABC transporter
SAS_RS12775	COG1363	Peptidase, m42
SAS_RS12795	COG4808	Protein conserved in bacteria
SAS_RS12800	COG0069	glutamate synthase activity
SAS_RS12815	COG1124	(ABC) transporter
SAS_RS12820	COG0444	Belongs to the ABC transporter superfamily
SAS_RS12825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAS_RS12860	COG1028	Short-chain dehydrogenase reductase Sdr
SAS_RS12865	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SAS_RS12870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAS_RS12945	COG0494	nUDIX hydrolase
SAS_RS12985	COG1846	Transcriptional regulator
SAS_RS13020	COG1070	Carbohydrate kinase
SAS_RS13025	COG1802	Transcriptional regulator
SAS_RS13030	COG0789	Transcriptional regulator
SAS_RS13035	COG2357	RelA SpoT domain protein
SAS_RS13040	COG4876	unkown
SAS_RS13050	COG2271	Major facilitator Superfamily
SAS_RS13055	COG0586	Pfam SNARE associated Golgi protein
SAS_RS13060	COG1131	(ABC) transporter
SAS_RS13080	COG3949	Membrane
SAS_RS13085	COG0400	carboxylic ester hydrolase activity
SAS_RS13090	COG0346	lactoylglutathione lyase activity
SAS_RS13095	COG1846	Transcriptional regulator
SAS_RS13120	COG0561	phosphatase activity
SAS_RS13125	COG1131	(ABC) transporter
SAS_RS13135	COG3764	Sortase (surface protein transpeptidase)
SAS_RS13155	COG1760	l-serine dehydratase
SAS_RS13160	COG1760	l-serine dehydratase
SAS_RS13175	COG0697	spore germination
SAS_RS13180	COG0657	acetylesterase activity
SAS_RS13200	COG0028	Belongs to the TPP enzyme family
SAS_RS13215	COG0583	DNA-binding transcription factor activity
SAS_RS13225	COG3942	CHAP domain
SAS_RS13235	COG3425	synthase
SAS_RS13240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SAS_RS13265	COG2409	Drug exporters of the RND superfamily
SAS_RS13310	COG0436	Aminotransferase
SAS_RS13340	COG3942	CHAP domain
SAS_RS13345	COG2755	lipolytic protein G-D-S-L family
SAS_RS13345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAS_RS13455	COG3001	Fructosamine kinase
SAS_RS13460	COG0167	dihydroorotate dehydrogenase activity
SAS_RS13515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAS_RS13520	COG3527	Alpha-acetolactate decarboxylase
SAS_RS13535	COG0531	amino acid
SAS_RS13565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAS_RS13585	COG1012	belongs to the aldehyde dehydrogenase family
SAS_RS13595	COG1510	regulation of RNA biosynthetic process
SAS_RS13605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAS_RS13630	COG2851	Citrate transporter
SAS_RS13640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SAS_RS13650	COG0386	Belongs to the glutathione peroxidase family
SAS_RS13675	COG1136	(ABC) transporter
SAS_RS13680	COG2205	protein histidine kinase activity
SAS_RS13685	COG0745	RESPONSE REGULATOR receiver
SAS_RS13700	COG1785	Belongs to the alkaline phosphatase family
SAS_RS13705	COG1846	Transcriptional regulator
SAS_RS13750	COG1438	arginine binding
SAS_RS13770	COG3711	transcriptional antiterminator
SAS_RS13770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAS_RS13775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAS_RS13775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAS_RS13775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAS_RS13780	COG1482	cell wall glycoprotein biosynthetic process
SAS_RS13790	COG3942	CHAP domain
SAS_RS13790	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAS_RS13795	COG1535	isochorismatase
SAS_RS13795	COG3433	isochorismatase activity
SAS_RS13810	COG0438	transferase activity, transferring glycosyl groups
SAS_RS13825	COG1073	alpha beta
SAS_RS13845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAS_RS13865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAS_RS13920	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SAS_RS13955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SAS_RS14040	COG0471	metal ion transport
SAS_RS14045	COG2962	Rard protein
SAS_RS14055	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SAS_RS14070	COG1136	(ABC) transporter
SAS_RS14075	COG0577	efflux transmembrane transporter activity
SAS_RS14085	COG1278	Cold shock
SAS_RS14105	COG1475	DNA binding