locus-tag	class	description
SAV_RS00160	COG2501	S4 domain
SAV_RS00180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SAV_RS00205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SAV_RS00215	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SAV_RS00225	COG0305	Participates in initiation and elongation during chromosome replication
SAV_RS00255	COG4863	YycH protein
SAV_RS00265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SAV_RS00270	COG0737	Belongs to the 5'-nucleotidase family
SAV_RS00330	COG0584	glycerophosphoryl diester phosphodiesterase
SAV_RS00335	COG2030	dehydratase
SAV_RS00355	COG1940	carbohydrate kinase activity
SAV_RS00355	COG1846	Transcriptional regulator
SAV_RS00365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAV_RS00370	COG2210	Belongs to the sulfur carrier protein TusA family
SAV_RS00375	COG1937	Protein conserved in bacteria
SAV_RS00380	COG0730	response to heat
SAV_RS00385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SAV_RS00415	COG2003	Belongs to the UPF0758 family
SAV_RS00460	COG2801	Transposase and inactivated derivatives
SAV_RS00470	COG1288	antiporter activity
SAV_RS00475	COG0745	RESPONSE REGULATOR receiver
SAV_RS00480	COG2205	protein histidine kinase activity
SAV_RS00555	COG0730	response to heat
SAV_RS00560	COG1937	Protein conserved in bacteria
SAV_RS00565	COG2210	Belongs to the sulfur carrier protein TusA family
SAV_RS00570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAV_RS00615	COG0823	Involved in the tonB-independent uptake of proteins
SAV_RS00650	COG1473	amidohydrolase
SAV_RS00660	COG1283	sodium-dependent phosphate transmembrane transporter activity
SAV_RS00665	COG4716	Myosin-crossreactive antigen
SAV_RS00670	COG0697	spore germination
SAV_RS00685	COG1620	l-lactate permease
SAV_RS00700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAV_RS00705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAV_RS00710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAV_RS00720	COG2423	ornithine cyclodeaminase activity
SAV_RS00725	COG4264	IucA IucC family
SAV_RS00730	COG2814	Major facilitator Superfamily
SAV_RS00735	COG4264	IucA IucC family
SAV_RS00740	COG4264	IucA IucC family
SAV_RS00750	COG0019	diaminopimelate decarboxylase activity
SAV_RS00755	COG1475	DNA binding
SAV_RS00780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAV_RS00785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAV_RS00790	COG0438	transferase activity, transferring glycosyl groups
SAV_RS00825	COG0813	purine-nucleoside phosphorylase activity
SAV_RS00830	COG2814	Major facilitator Superfamily
SAV_RS00850	COG3639	organic phosphonate transmembrane transporter activity
SAV_RS00870	COG0737	Belongs to the 5'-nucleotidase family
SAV_RS00885	COG1454	alcohol dehydrogenase
SAV_RS00885	COG1012	belongs to the aldehyde dehydrogenase family
SAV_RS00910	COG1086	Polysaccharide biosynthesis protein
SAV_RS00920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAV_RS00950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAV_RS00960	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SAV_RS00965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAV_RS00975	COG2832	Protein of unknown function (DUF454)
SAV_RS01015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SAV_RS01020	COG1960	acyl-CoA dehydrogenase activity
SAV_RS01025	COG5609	conserved protein (DUF2294)
SAV_RS01075	COG1114	Component of the transport system for branched-chain amino acids
SAV_RS01080	COG1335	isochorismatase
SAV_RS01085	COG3961	Belongs to the TPP enzyme family
SAV_RS01115	COG1737	Transcriptional regulator
SAV_RS01140	COG1136	(ABC) transporter
SAV_RS01145	COG0577	efflux transmembrane transporter activity
SAV_RS01145	COG1136	(ABC) transporter
SAV_RS01165	COG1131	(ABC) transporter
SAV_RS01180	COG0601	transmembrane transport
SAV_RS01185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAV_RS01195	COG0405	Gamma-glutamyltransferase
SAV_RS01215	COG3842	ATPase activity
SAV_RS01225	COG1175	transmembrane transport
SAV_RS01230	COG3833	ABC-type maltose transport systems, permease component
SAV_RS01235	COG0673	inositol 2-dehydrogenase activity
SAV_RS01240	COG0673	inositol 2-dehydrogenase activity
SAV_RS01250	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAV_RS01310	COG0183	Belongs to the thiolase family
SAV_RS01320	COG1960	acyl-CoA dehydrogenase activity
SAV_RS01325	COG0318	PFAM AMP-dependent synthetase and ligase
SAV_RS01340	COG0747	negative chemotaxis
SAV_RS01345	COG3189	MarR family transcriptional regulator
SAV_RS01375	COG2190	(PTS) system
SAV_RS01375	COG1263	PTS System
SAV_RS01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAV_RS01380	COG1957	nucleoside hydrolase
SAV_RS01400	COG3414	Phosphotransferase system galactitol-specific IIB component
SAV_RS01405	COG3775	system Galactitol-specific IIC component
SAV_RS01410	COG1063	alcohol dehydrogenase
SAV_RS01420	COG1063	alcohol dehydrogenase
SAV_RS01430	COG1063	alcohol dehydrogenase
SAV_RS01435	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAV_RS01440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAV_RS01450	COG1063	alcohol dehydrogenase
SAV_RS01455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAV_RS01490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAV_RS01495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAV_RS01495	COG2190	(PTS) system
SAV_RS01495	COG1263	PTS System
SAV_RS01500	COG2723	6-phospho-beta-galactosidase activity
SAV_RS01510	COG2226	methyltransferase
SAV_RS01565	COG1131	(ABC) transporter
SAV_RS01585	COG1388	LysM domain
SAV_RS01585	COG3942	CHAP domain
SAV_RS01705	COG1114	Component of the transport system for branched-chain amino acids
SAV_RS01710	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SAV_RS01720	COG0577	efflux transmembrane transporter activity
SAV_RS01745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAV_RS01750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SAV_RS01775	COG3314	Sporulation integral membrane protein YlbJ
SAV_RS01800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAV_RS01830	COG3037	sugar-specific permease SgaT UlaA
SAV_RS01840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAV_RS01845	COG3711	transcriptional antiterminator
SAV_RS01865	COG2271	Major facilitator Superfamily
SAV_RS01870	COG2271	Major facilitator Superfamily
SAV_RS01875	COG0346	lactoylglutathione lyase activity
SAV_RS01880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAV_RS01885	COG0431	NADPH-dependent FMN reductase
SAV_RS01900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAV_RS01905	COG2822	iron ion transport
SAV_RS01915	COG0672	)-iron permease
SAV_RS01920	COG0805	protein transport
SAV_RS01925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SAV_RS01935	COG1476	TRANSCRIPTIONal
SAV_RS01945	COG1131	(ABC) transporter
SAV_RS01980	COG0646	methionine synthase
SAV_RS01980	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SAV_RS01985	COG0626	cystathionine gamma-synthase activity
SAV_RS01990	COG0626	cystathionine gamma-synthase activity
SAV_RS01995	COG1475	DNA binding
SAV_RS02000	COG0668	transmembrane transport
SAV_RS02005	COG4481	Protein conserved in bacteria
SAV_RS02010	COG0012	GTP binding
SAV_RS02110	COG1823	symporter activity
SAV_RS02145	COG2233	PERMEase
SAV_RS02160	COG0582	viral genome integration into host DNA
SAV_RS02195	COG0791	NLP P60 protein
SAV_RS02195	COG0741	lytic transglycosylase activity
SAV_RS02235	COG2946	Replication initiation factor
SAV_RS02240	COG1674	ftsk spoiiie
SAV_RS02270	COG3328	transposase activity
SAV_RS02295	COG3759	membrane
SAV_RS02455	COG0523	cobalamin synthesis protein
SAV_RS02465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SAV_RS02475	COG5609	conserved protein (DUF2294)
SAV_RS02490	COG1647	Serine aminopeptidase, S33
SAV_RS02495	COG0733	neurotransmitter:sodium symporter activity
SAV_RS02500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAV_RS02505	COG0626	cystathionine gamma-synthase activity
SAV_RS02515	COG2011	ABC-type metal ion transport system permease component
SAV_RS02520	COG1464	Belongs to the NlpA lipoprotein family
SAV_RS02555	COG0583	DNA-binding transcription factor activity
SAV_RS02560	COG0067	glutamate synthase
SAV_RS02560	COG0069	glutamate synthase activity
SAV_RS02560	COG0070	glutamate synthase
SAV_RS02565	COG0493	'glutamate synthase
SAV_RS02575	COG1263	PTS System
SAV_RS02575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAV_RS02580	COG0366	Alpha amylase catalytic
SAV_RS02585	COG2188	Transcriptional regulator
SAV_RS02600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAV_RS02635	COG1982	Orn Lys Arg decarboxylase major
SAV_RS02645	COG3870	Protein conserved in bacteria
SAV_RS02655	COG0470	DNA polymerase III
SAV_RS02660	COG1774	PSP1 C-terminal conserved region
SAV_RS02670	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SAV_RS02680	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SAV_RS02695	COG0084	hydrolase, TatD family'
SAV_RS02700	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAV_RS02710	COG4466	Protein conserved in bacteria
SAV_RS02720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAV_RS02725	COG0251	oxidation-reduction process
SAV_RS02770	COG2244	polysaccharide biosynthetic process
SAV_RS02775	COG3956	TIGRFAM MazG family protein
SAV_RS02780	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SAV_RS02790	COG1098	S1 RNA binding domain
SAV_RS02805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAV_RS02830	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SAV_RS02910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAV_RS02925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAV_RS02935	COG3880	PFAM UvrB UvrC protein
SAV_RS02955	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SAV_RS02960	COG4956	integral membrane protein (PIN domain superfamily)
SAV_RS02980	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SAV_RS03030	COG2813	Specifically methylates the guanine in position
SAV_RS03070	COG1473	amidohydrolase
SAV_RS03100	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SAV_RS03105	COG1428	Deoxynucleoside kinase
SAV_RS03110	COG1428	Deoxynucleoside kinase
SAV_RS03120	COG0561	phosphatase activity
SAV_RS03160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SAV_RS03175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SAV_RS03265	COG0095	Lipoate-protein ligase
SAV_RS03270	COG0083	homoserine kinase activity
SAV_RS03290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAV_RS03325	COG0667	Aldo Keto reductase
SAV_RS03335	COG0655	NAD(P)H dehydrogenase (quinone) activity
SAV_RS03345	COG1078	dGTPase activity
SAV_RS03380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAV_RS03385	COG4139	cobalamin transport
SAV_RS03435	COG4974	Belongs to the 'phage' integrase family
SAV_RS03485	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAV_RS03490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAV_RS03495	COG1121	(ABC) transporter
SAV_RS03500	COG1321	iron dependent repressor
SAV_RS03510	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SAV_RS03520	COG1682	transport, permease protein
SAV_RS03525	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAV_RS03535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SAV_RS03540	COG1686	Belongs to the peptidase S11 family
SAV_RS03545	COG1132	(ABC) transporter
SAV_RS03550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAV_RS03560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAV_RS03565	COG1120	ATPase activity
SAV_RS03570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAV_RS03575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAV_RS03580	COG2376	Dihydroxyacetone kinase
SAV_RS03590	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SAV_RS03600	COG3949	Membrane
SAV_RS03625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAV_RS03640	COG1136	(ABC) transporter
SAV_RS03645	COG0577	efflux transmembrane transporter activity
SAV_RS03650	COG1392	Phosphate transport regulator
SAV_RS03655	COG0306	phosphate transporter
SAV_RS03660	COG1388	LysM domain
SAV_RS03660	COG3942	CHAP domain
SAV_RS03670	COG1917	Cupin 2, conserved barrel domain protein
SAV_RS03670	COG4977	sequence-specific DNA binding
SAV_RS03700	COG0583	DNA-binding transcription factor activity
SAV_RS03705	COG2814	Major facilitator Superfamily
SAV_RS03710	COG2839	Protein conserved in bacteria
SAV_RS03740	COG1611	Belongs to the LOG family
SAV_RS03760	COG4988	ABC transporter
SAV_RS03765	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAV_RS03775	COG0523	cobalamin synthesis protein
SAV_RS03780	COG4989	oxidoreductase activity
SAV_RS03790	COG0471	metal ion transport
SAV_RS03795	COG0415	Belongs to the DNA photolyase family
SAV_RS03825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAV_RS03830	COG1349	DNA-binding transcription factor activity
SAV_RS03835	COG1105	Belongs to the carbohydrate kinase PfkB family
SAV_RS03840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAV_RS03840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAV_RS03840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAV_RS03850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SAV_RS03855	COG1253	flavin adenine dinucleotide binding
SAV_RS03860	COG0656	L-ascorbic acid biosynthetic process
SAV_RS03865	COG0463	Glycosyl transferase, family 2
SAV_RS03900	COG0720	synthase
SAV_RS03910	COG0512	Glutamine amidotransferase of anthranilate synthase
SAV_RS03910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SAV_RS03915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAV_RS03950	COG0488	(ABC) transporter
SAV_RS03955	COG0514	ATP-dependent DNA helicase (RecQ)
SAV_RS03960	COG0517	IMP dehydrogenase activity
SAV_RS03960	COG1125	glycine betaine transport
SAV_RS03965	COG1174	glycine betaine transport
SAV_RS03995	COG3104	oligopeptide transport
SAV_RS04015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAV_RS04020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAV_RS04030	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAV_RS04035	COG4605	iron ion homeostasis
SAV_RS04040	COG4604	ABC transporter, ATP-binding protein
SAV_RS04045	COG4607	ABC-type enterochelin transport system periplasmic component
SAV_RS04100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAV_RS04105	COG1739	Uncharacterized protein family UPF0029
SAV_RS04115	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SAV_RS04120	COG1040	competence protein
SAV_RS04150	COG3942	CHAP domain
SAV_RS04150	COG1388	LysM domain
SAV_RS04210	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SAV_RS04275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SAV_RS04280	COG1647	Serine aminopeptidase, S33
SAV_RS04285	COG0557	exoribonuclease II activity
SAV_RS04380	COG5484	DNA packaging
SAV_RS04380	COG3728	DNA packaging
SAV_RS04395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAV_RS04400	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SAV_RS04465	COG1278	Cold shock
SAV_RS04505	COG0406	alpha-ribazole phosphatase activity
SAV_RS04510	COG1279	arginine transmembrane transporter activity
SAV_RS04535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAV_RS04540	COG1393	Belongs to the ArsC family
SAV_RS04555	COG3878	Protein conserved in bacteria
SAV_RS04565	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAV_RS04580	COG2011	ABC-type metal ion transport system permease component
SAV_RS04585	COG1464	Belongs to the NlpA lipoprotein family
SAV_RS04600	COG0396	ATPase activity
SAV_RS04605	COG0719	Fe-S assembly protein
SAV_RS04615	COG0822	iron-sulfur transferase activity
SAV_RS04740	COG1484	DNA-dependent DNA replication
SAV_RS04830	COG1783	phage Terminase large subunit
SAV_RS04960	COG5632	N-Acetylmuramoyl-L-alanine amidase
SAV_RS04960	COG1388	LysM domain
SAV_RS05000	COG1253	flavin adenine dinucleotide binding
SAV_RS05015	COG1801	Protein of unknown function DUF72
SAV_RS05020	COG0730	response to heat
SAV_RS05035	COG4470	Protein conserved in bacteria
SAV_RS05050	COG2445	Protein of unknown function DUF86
SAV_RS05080	COG1696	Membrane protein involved in D-alanine export
SAV_RS05090	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SAV_RS05095	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SAV_RS05100	COG4837	Protein of unknown function (DUF1462)
SAV_RS05105	COG1252	NADH dehydrogenase
SAV_RS05115	COG0316	Belongs to the HesB IscA family
SAV_RS05125	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SAV_RS05130	COG2056	Na+-H+ antiporter family
SAV_RS05135	COG2050	protein possibly involved in aromatic compounds catabolism
SAV_RS05190	COG1098	S1 RNA binding domain
SAV_RS05195	COG1902	pentaerythritol trinitrate reductase activity
SAV_RS05210	COG0584	glycerophosphoryl diester phosphodiesterase
SAV_RS05230	COG0398	Pfam SNARE associated Golgi protein
SAV_RS05270	COG0561	phosphatase activity
SAV_RS05295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SAV_RS05310	COG1881	PFAM PEBP family protein
SAV_RS05340	COG0601	transmembrane transport
SAV_RS05345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAV_RS05350	COG0444	Belongs to the ABC transporter superfamily
SAV_RS05355	COG4608	Belongs to the ABC transporter superfamily
SAV_RS05360	COG4166	transmembrane transport
SAV_RS05365	COG0747	negative chemotaxis
SAV_RS05370	COG0444	Belongs to the ABC transporter superfamily
SAV_RS05375	COG4608	Belongs to the ABC transporter superfamily
SAV_RS05380	COG0601	transmembrane transport
SAV_RS05385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAV_RS05410	COG1164	Oligoendopeptidase f
SAV_RS05420	COG2346	COG2346, Truncated hemoglobins
SAV_RS05435	COG2357	RelA SpoT domain protein
SAV_RS05445	COG0564	pseudouridine synthase activity
SAV_RS05450	COG2239	Acts as a magnesium transporter
SAV_RS05455	COG0569	domain protein
SAV_RS05455	COG0475	glutathione-regulated potassium exporter activity
SAV_RS05465	COG0628	permease
SAV_RS05470	COG1115	amino acid carrier protein
SAV_RS05510	COG0861	Integral membrane protein TerC family
SAV_RS05520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAV_RS05525	COG0737	Belongs to the 5'-nucleotidase family
SAV_RS05540	COG4903	ComK protein
SAV_RS05555	COG4873	Protein conserved in bacteria
SAV_RS05600	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAV_RS05610	COG2314	TM2 domain
SAV_RS05615	COG0456	acetyltransferase
SAV_RS05620	COG1575	Belongs to the MenA family. Type 1 subfamily
SAV_RS05625	COG1169	isochorismate synthase
SAV_RS05635	COG2267	carboxylic ester hydrolase activity
SAV_RS05660	COG0436	Aminotransferase
SAV_RS05665	COG3594	Acyltransferase
SAV_RS05695	COG1316	TRANSCRIPTIONal
SAV_RS05740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SAV_RS05755	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAV_RS05795	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SAV_RS05800	COG4172	Belongs to the ABC transporter superfamily
SAV_RS05805	COG4721	ABC-type cobalt transport system, permease component
SAV_RS05830	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAV_RS05850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SAV_RS05855	COG1271	oxidase subunit
SAV_RS05860	COG1294	oxidase, subunit
SAV_RS05865	COG0569	domain protein
SAV_RS05930	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAV_RS05935	COG1177	transmembrane transport
SAV_RS05940	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SAV_RS05965	COG0483	inositol monophosphate 1-phosphatase activity
SAV_RS05975	COG1217	gtp-binding protein TYPA
SAV_RS05985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SAV_RS05995	COG0772	Belongs to the SEDS family
SAV_RS06030	COG3679	Belongs to the UPF0342 family
SAV_RS06050	COG0742	ribosomal rna small subunit methyltransferase
SAV_RS06110	COG4509	Sortase family
SAV_RS06125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAV_RS06155	COG1796	DNA polymerase
SAV_RS06155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SAV_RS06180	COG2009	succinate dehydrogenase
SAV_RS06185	COG1053	succinate dehydrogenase
SAV_RS06190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SAV_RS06315	COG1288	antiporter activity
SAV_RS06350	COG1011	Hydrolase
SAV_RS06375	COG4839	cell division protein FtsL
SAV_RS06380	COG0768	penicillin binding
SAV_RS06395	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SAV_RS06400	COG0849	cell division
SAV_RS06415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAV_RS06425	COG0762	integral membrane protein
SAV_RS06430	COG2302	S4 RNA-binding domain
SAV_RS06435	COG3599	regulation of cell shape
SAV_RS06445	COG2514	catechol 2,3-dioxygenase activity
SAV_RS06460	COG0564	pseudouridine synthase activity
SAV_RS06470	COG2233	PERMEase
SAV_RS06515	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SAV_RS06530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SAV_RS06535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SAV_RS06545	COG2314	TM2 domain
SAV_RS06560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAV_RS06560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAV_RS06570	COG0631	protein serine/threonine phosphatase activity
SAV_RS06585	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SAV_RS06600	COG1302	Protein conserved in bacteria
SAV_RS06650	COG1196	nuclear chromosome segregation
SAV_RS06655	COG0552	protein localization to endoplasmic reticulum
SAV_RS06665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SAV_RS06725	COG2348	transferase activity, transferring amino-acyl groups
SAV_RS06730	COG0758	DNA mediated transformation
SAV_RS06825	COG0195	Participates in both transcription termination and antitermination
SAV_RS06830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SAV_RS06855	COG0196	riboflavin kinase activity
SAV_RS06880	COG2188	Transcriptional regulator
SAV_RS06885	COG0612	Peptidase, M16
SAV_RS06890	COG0612	Peptidase, M16
SAV_RS06895	COG0300	oxidoreductase activity
SAV_RS06915	COG1546	Belongs to the CinA family
SAV_RS06915	COG1058	Belongs to the CinA family
SAV_RS06935	COG1692	metallophosphoesterase
SAV_RS06940	COG0674	pyruvate-flavodoxin oxidoreductase activity
SAV_RS06940	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SAV_RS06945	COG1013	pyruvate-flavodoxin oxidoreductase activity
SAV_RS06980	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SAV_RS06985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAV_RS07010	COG1923	regulation of RNA biosynthetic process
SAV_RS07020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAV_RS07025	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SAV_RS07030	COG0789	Transcriptional regulator
SAV_RS07125	COG2197	response regulator
SAV_RS07135	COG1525	nuclease
SAV_RS07150	COG0527	aspartate kinase activity
SAV_RS07155	COG0460	homoserine dehydrogenase
SAV_RS07160	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SAV_RS07185	COG0833	amino acid
SAV_RS07215	COG2340	Cysteine-rich secretory protein family
SAV_RS07250	COG4846	Membrane protein involved in cytochrome C biogenesis
SAV_RS07270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAV_RS07280	COG0824	Thioesterase
SAV_RS07310	COG1115	amino acid carrier protein
SAV_RS07325	COG0628	permease
SAV_RS07350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SAV_RS07360	COG1363	Peptidase, m42
SAV_RS07365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAV_RS07370	COG0512	Glutamine amidotransferase of anthranilate synthase
SAV_RS07415	COG0561	phosphatase activity
SAV_RS07460	COG0704	Plays a role in the regulation of phosphate uptake
SAV_RS07470	COG0581	inorganic phosphate transmembrane transporter activity
SAV_RS07475	COG0573	inorganic phosphate transmembrane transporter activity
SAV_RS07500	COG0488	(ABC) transporter
SAV_RS07505	COG0527	aspartate kinase activity
SAV_RS07510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SAV_RS07585	COG4548	von Willebrand factor, type A
SAV_RS07590	COG0714	Associated with various cellular activities
SAV_RS07635	COG0671	phosphoesterase, PA-phosphatase related
SAV_RS07715	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SAV_RS07745	COG0531	amino acid
SAV_RS07760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAV_RS07765	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SAV_RS07785	COG0116	Belongs to the methyltransferase superfamily
SAV_RS07815	COG4499	WXG100 protein secretion system (Wss), protein YukC
SAV_RS07815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAV_RS07825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SAV_RS07830	COG3935	DnaD domain protein
SAV_RS07855	COG0438	transferase activity, transferring glycosyl groups
SAV_RS07860	COG1694	Mazg nucleotide pyrophosphohydrolase
SAV_RS07865	COG2738	Putative neutral zinc metallopeptidase
SAV_RS07870	COG4347	Protein of unknown function (DUF1405)
SAV_RS07910	COG0142	geranyltranstransferase activity
SAV_RS07975	COG0492	ferredoxin-NADP+ reductase activity
SAV_RS07990	COG0514	ATP-dependent DNA helicase (RecQ)
SAV_RS08000	COG1141	Ferredoxin
SAV_RS08050	COG0745	RESPONSE REGULATOR receiver
SAV_RS08055	COG1187	pseudouridine synthase activity
SAV_RS08080	COG0735	belongs to the Fur family
SAV_RS08085	COG0494	nUDIX hydrolase
SAV_RS08090	COG0667	Aldo Keto reductase
SAV_RS08100	COG4221	oxidoreductase activity
SAV_RS08115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SAV_RS08125	COG0366	Alpha amylase catalytic
SAV_RS08130	COG1609	Transcriptional regulator
SAV_RS08155	COG2195	Cleaves the N-terminal amino acid of tripeptides
SAV_RS08165	COG4129	membrane
SAV_RS08175	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAV_RS08180	COG0022	dehydrogenase e1 component
SAV_RS08185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SAV_RS08190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAV_RS08195	COG0497	DNA recombination
SAV_RS08225	COG1302	Protein conserved in bacteria
SAV_RS08230	COG0439	Biotin carboxylase
SAV_RS08235	COG0511	ligase activity, forming carbon-carbon bonds
SAV_RS08245	COG0006	proline dipeptidase activity
SAV_RS08260	COG0095	Lipoate-protein ligase
SAV_RS08265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAV_RS08310	COG4537	Required for transformation and DNA binding
SAV_RS08315	COG1459	type II secretion system
SAV_RS08320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SAV_RS08325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAV_RS08330	COG0011	TIGRFAM Protein of
SAV_RS08335	COG1940	carbohydrate kinase activity
SAV_RS08340	COG4483	Protein conserved in bacteria
SAV_RS08350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAV_RS08360	COG0768	penicillin binding
SAV_RS08375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAV_RS08380	COG1121	(ABC) transporter
SAV_RS08390	COG0513	Belongs to the DEAD box helicase family
SAV_RS08400	COG2384	SAM-dependent methyltransferase
SAV_RS08420	COG0517	IMP dehydrogenase activity
SAV_RS08440	COG0295	cytidine deaminase activity
SAV_RS08455	COG1702	phosphate starvation-inducible protein PhoH
SAV_RS08470	COG1030	water channel activity
SAV_RS08480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SAV_RS08485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SAV_RS08515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAV_RS08535	COG1466	dna polymerase III delta subunit
SAV_RS08540	COG0658	competence protein
SAV_RS08540	COG2333	competence protein COMEC
SAV_RS08545	COG2131	deaminase
SAV_RS08550	COG2183	response to ionizing radiation
SAV_RS08555	COG2226	methyltransferase
SAV_RS08560	COG0799	negative regulation of ribosome biogenesis
SAV_RS08565	COG1713	HD superfamily hydrolase involved in NAD metabolism
SAV_RS08575	COG1534	Rna-binding protein
SAV_RS08585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAV_RS08590	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SAV_RS08620	COG3177	Filamentation induced by cAMP protein fic
SAV_RS08625	COG1914	H( )-stimulated, divalent metal cation uptake system
SAV_RS08635	COG0439	Biotin carboxylase
SAV_RS08640	COG0511	ligase activity, forming carbon-carbon bonds
SAV_RS08645	COG1984	allophanate hydrolase subunit 2
SAV_RS08650	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SAV_RS08665	COG0826	peptidase U32
SAV_RS08670	COG0826	peptidase U32
SAV_RS08700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAV_RS08715	COG1104	cysteine desulfurase activity
SAV_RS08720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAV_RS08730	COG3237	CsbD-like
SAV_RS08735	COG1959	2 iron, 2 sulfur cluster binding
SAV_RS08740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SAV_RS08745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SAV_RS08785	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SAV_RS08785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SAV_RS08790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAV_RS08790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAV_RS08795	COG1862	Preprotein translocase
SAV_RS08835	COG2868	ribosomal protein
SAV_RS08870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SAV_RS08905	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SAV_RS08915	COG0285	dihydrofolate synthase activity
SAV_RS08925	COG2818	Glycosylase
SAV_RS08960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SAV_RS08995	COG4112	unkown
SAV_RS09020	COG0833	amino acid
SAV_RS09035	COG1484	DNA-dependent DNA replication
SAV_RS09065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAV_RS09065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAV_RS09075	COG5002	protein histidine kinase activity
SAV_RS09080	COG0745	RESPONSE REGULATOR receiver
SAV_RS09095	COG0372	Belongs to the citrate synthase family
SAV_RS09100	COG1113	amino acid transport
SAV_RS09130	COG0281	malic enzyme
SAV_RS09140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SAV_RS09145	COG4109	DRTGG domain
SAV_RS09185	COG0827	DNA restriction-modification system
SAV_RS09195	COG0730	response to heat
SAV_RS09205	COG1104	cysteine desulfurase activity
SAV_RS09220	COG1956	GAF domain-containing protein
SAV_RS09240	COG0584	glycerophosphoryl diester phosphodiesterase
SAV_RS09245	COG1764	response to oxidative stress
SAV_RS09250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SAV_RS09255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAV_RS09270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAV_RS09270	COG1263	PTS System
SAV_RS09275	COG0204	Acyl-transferase
SAV_RS09280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAV_RS09315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAV_RS09320	COG0454	-acetyltransferase
SAV_RS09340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SAV_RS09340	COG1605	Chorismate mutase
SAV_RS09365	COG1674	ftsk spoiiie
SAV_RS09370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAV_RS09380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAV_RS09385	COG1363	Peptidase, m42
SAV_RS09395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAV_RS09405	COG0510	thiamine kinase activity
SAV_RS09425	COG1187	pseudouridine synthase activity
SAV_RS09430	COG2244	polysaccharide biosynthetic process
SAV_RS09460	COG2814	Major facilitator Superfamily
SAV_RS09465	COG1242	4 iron, 4 sulfur cluster binding
SAV_RS09470	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SAV_RS09480	COG2267	carboxylic ester hydrolase activity
SAV_RS09510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAV_RS09510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAV_RS09530	COG5632	N-Acetylmuramoyl-L-alanine amidase
SAV_RS09530	COG4193	domain, Protein
SAV_RS09530	COG3266	domain, Protein
SAV_RS09560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SAV_RS09600	COG0656	L-ascorbic acid biosynthetic process
SAV_RS09620	COG1506	peptidase
SAV_RS09625	COG2816	NAD+ diphosphatase activity
SAV_RS09880	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SAV_RS09910	COG1131	(ABC) transporter
SAV_RS09915	COG0537	adenosine 5'-monophosphoramidase activity
SAV_RS09945	COG0420	3'-5' exonuclease activity
SAV_RS09970	COG2197	response regulator
SAV_RS09975	COG2203	Gaf domain
SAV_RS09975	COG4585	Histidine kinase
SAV_RS09980	COG0564	pseudouridine synthase activity
SAV_RS10010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SAV_RS10015	COG1126	abc transporter atp-binding protein
SAV_RS10020	COG0765	amino acid transport
SAV_RS10190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAV_RS10195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SAV_RS10205	COG4129	membrane
SAV_RS10230	COG1988	membrane-bound metal-dependent
SAV_RS10245	COG1134	teichoic acid transport
SAV_RS10245	COG1388	LysM domain
SAV_RS10275	COG0535	radical SAM domain protein
SAV_RS10280	COG1607	acyl-coa hydrolase
SAV_RS10285	COG2309	aminopeptidase activity
SAV_RS10305	COG1295	ribonuclease BN
SAV_RS10425	COG4851	CamS sex pheromone cAM373 precursor
SAV_RS10445	COG4496	protein, YerC YecD
SAV_RS10480	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SAV_RS10490	COG0077	Prephenate dehydratase
SAV_RS10500	COG0471	metal ion transport
SAV_RS10510	COG1335	isochorismatase
SAV_RS10525	COG1012	belongs to the aldehyde dehydrogenase family
SAV_RS10575	COG1131	(ABC) transporter
SAV_RS10590	COG1725	Transcriptional regulator
SAV_RS10645	COG0860	N-Acetylmuramoyl-L-alanine amidase
SAV_RS10645	COG1388	LysM domain
SAV_RS10655	COG1388	LysM domain
SAV_RS10655	COG5632	N-Acetylmuramoyl-L-alanine amidase
SAV_RS10705	COG0739	heme binding
SAV_RS10755	COG0740	serine-type endopeptidase activity
SAV_RS10925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SAV_RS10970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAV_RS10995	COG3728	DNA packaging
SAV_RS10995	COG5484	DNA packaging
SAV_RS11075	COG0582	viral genome integration into host DNA
SAV_RS11140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAV_RS11145	COG1621	beta-fructofuranosidase activity
SAV_RS11150	COG1609	Transcriptional regulator
SAV_RS11155	COG0004	ammonium transporteR
SAV_RS11160	COG0425	Belongs to the sulfur carrier protein TusA family
SAV_RS11165	COG2391	methyltransferase activity
SAV_RS11175	COG0488	(ABC) transporter
SAV_RS11185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SAV_RS11195	COG0456	acetyltransferase
SAV_RS11200	COG1214	PFAM Peptidase M22, glycoprotease
SAV_RS11205	COG0802	atpase or kinase
SAV_RS11220	COG0028	Belongs to the TPP enzyme family
SAV_RS11290	COG2183	response to ionizing radiation
SAV_RS11295	COG1191	sigma factor activity
SAV_RS11305	COG1366	Belongs to the anti-sigma-factor antagonist family
SAV_RS11310	COG2208	phosphoserine phosphatase activity
SAV_RS11345	COG3428	Bacterial PH domain
SAV_RS11375	COG2205	protein histidine kinase activity
SAV_RS11380	COG0745	RESPONSE REGULATOR receiver
SAV_RS11395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAV_RS11405	COG0772	Belongs to the SEDS family
SAV_RS11420	COG1937	Protein conserved in bacteria
SAV_RS11430	COG1418	mRNA catabolic process
SAV_RS11475	COG0629	single-stranded DNA binding
SAV_RS11550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAV_RS11575	COG0009	L-threonylcarbamoyladenylate synthase
SAV_RS11580	COG2890	protein-(glutamine-N5) methyltransferase activity
SAV_RS11600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SAV_RS11640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAV_RS11690	COG0813	purine-nucleoside phosphorylase activity
SAV_RS11695	COG0783	Belongs to the Dps family
SAV_RS11715	COG1482	cell wall glycoprotein biosynthetic process
SAV_RS11720	COG0702	epimerase
SAV_RS11725	COG0640	Transcriptional regulator
SAV_RS11745	COG0561	phosphatase activity
SAV_RS11750	COG1119	ATPase activity
SAV_RS11765	COG3711	transcriptional antiterminator
SAV_RS11795	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SAV_RS11855	COG0489	protein tyrosine kinase activity
SAV_RS11860	COG2814	Major facilitator Superfamily
SAV_RS11875	COG1272	protein, Hemolysin III
SAV_RS11885	COG1988	membrane-bound metal-dependent
SAV_RS11895	COG3314	Sporulation integral membrane protein YlbJ
SAV_RS11900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAV_RS11905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAV_RS11910	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAV_RS11920	COG3457	Alanine racemase
SAV_RS11925	COG4264	IucA IucC family
SAV_RS11930	COG2814	Major facilitator Superfamily
SAV_RS11955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAV_RS11965	COG2130	NADP-dependent
SAV_RS12030	COG0656	L-ascorbic acid biosynthetic process
SAV_RS12035	COG0789	Transcriptional regulator
SAV_RS12045	COG5492	domain, Protein
SAV_RS12065	COG3527	Alpha-acetolactate decarboxylase
SAV_RS12070	COG0028	Belongs to the TPP enzyme family
SAV_RS12175	COG0201	protein transport
SAV_RS12290	COG2252	PERMEase
SAV_RS12335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SAV_RS12400	COG1763	Mo-molybdopterin cofactor biosynthetic process
SAV_RS12420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SAV_RS12425	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SAV_RS12430	COG4149	molybdate abc transporter
SAV_RS12435	COG0725	ABC transporter, periplasmic molybdate-binding protein
SAV_RS12450	COG1268	BioY protein
SAV_RS12465	COG1960	acyl-CoA dehydrogenase activity
SAV_RS12470	COG4413	Urea transporter
SAV_RS12535	COG3942	CHAP domain
SAV_RS12545	COG1757	Na H antiporter
SAV_RS12560	COG3942	CHAP domain
SAV_RS12630	COG1113	amino acid transport
SAV_RS12650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAV_RS12655	COG0385	Bile acid
SAV_RS12665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAV_RS12665	COG1263	PTS System
SAV_RS12670	COG1737	Transcriptional regulator
SAV_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
SAV_RS12695	COG1473	amidohydrolase
SAV_RS12710	COG0583	DNA-binding transcription factor activity
SAV_RS12735	COG2258	MOSC domain
SAV_RS12755	COG1668	transmembrane transport
SAV_RS12760	COG4152	abc transporter atp-binding protein
SAV_RS12765	COG3152	Membrane
SAV_RS12775	COG0786	glutamate:sodium symporter activity
SAV_RS12785	COG0598	Magnesium transport protein CorA
SAV_RS12800	COG0657	acetylesterase activity
SAV_RS12810	COG2814	Major facilitator Superfamily
SAV_RS12815	COG1566	PFAM secretion protein HlyD family protein
SAV_RS12825	COG2814	Major facilitator Superfamily
SAV_RS12890	COG1620	l-lactate permease
SAV_RS12910	COG0604	alcohol dehydrogenase
SAV_RS12940	COG1511	domain protein
SAV_RS12955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAV_RS12955	COG1263	PTS System
SAV_RS12975	COG3871	stress protein (general stress protein 26)
SAV_RS13015	COG0789	Transcriptional regulator
SAV_RS13035	COG2181	nitrate reductase activity
SAV_RS13045	COG1140	nitrate reductase beta subunit
SAV_RS13050	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SAV_RS13060	COG2146	nitrite reductase [NAD(P)H] activity
SAV_RS13065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SAV_RS13075	COG0454	-acetyltransferase
SAV_RS13080	COG2116	formate transmembrane transporter activity
SAV_RS13095	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAV_RS13095	COG3443	Belongs to the bacterial solute-binding protein 9 family
SAV_RS13130	COG1126	abc transporter atp-binding protein
SAV_RS13135	COG0765	amino acid transport
SAV_RS13140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAV_RS13145	COG2814	Major facilitator Superfamily
SAV_RS13165	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SAV_RS13210	COG0156	8-amino-7-oxononanoate synthase activity
SAV_RS13220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SAV_RS13225	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SAV_RS13240	COG1132	(ABC) transporter
SAV_RS13245	COG1132	(ABC) transporter
SAV_RS13245	COG2375	cellular response to nickel ion
SAV_RS13265	COG1929	Belongs to the glycerate kinase type-1 family
SAV_RS13275	COG2814	Major facilitator Superfamily
SAV_RS13295	COG1113	amino acid transport
SAV_RS13310	COG0531	amino acid
SAV_RS13335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAV_RS13345	COG1174	glycine betaine transport
SAV_RS13355	COG1174	glycine betaine transport
SAV_RS13375	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SAV_RS13380	COG0531	amino acid
SAV_RS13385	COG2272	Belongs to the type-B carboxylesterase lipase family
SAV_RS13390	COG2814	Major facilitator Superfamily
SAV_RS13395	COG0390	transport system, permease component
SAV_RS13400	COG4619	ABC transporter
SAV_RS13405	COG1363	Peptidase, m42
SAV_RS13425	COG4808	Protein conserved in bacteria
SAV_RS13430	COG0069	glutamate synthase activity
SAV_RS13485	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SAV_RS13490	COG1028	Short-chain dehydrogenase reductase Sdr
SAV_RS13495	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SAV_RS13500	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAV_RS13585	COG0494	nUDIX hydrolase
SAV_RS13620	COG3583	domain protein
SAV_RS13630	COG1846	Transcriptional regulator
SAV_RS13670	COG1070	Carbohydrate kinase
SAV_RS13675	COG1802	Transcriptional regulator
SAV_RS13680	COG0789	Transcriptional regulator
SAV_RS13685	COG2357	RelA SpoT domain protein
SAV_RS13690	COG4876	unkown
SAV_RS13700	COG2271	Major facilitator Superfamily
SAV_RS13705	COG0586	Pfam SNARE associated Golgi protein
SAV_RS13715	COG1131	(ABC) transporter
SAV_RS13735	COG3949	Membrane
SAV_RS13740	COG0400	carboxylic ester hydrolase activity
SAV_RS13745	COG0346	lactoylglutathione lyase activity
SAV_RS13750	COG1846	Transcriptional regulator
SAV_RS13760	COG2514	catechol 2,3-dioxygenase activity
SAV_RS13775	COG0561	phosphatase activity
SAV_RS13780	COG1131	(ABC) transporter
SAV_RS13790	COG3764	Sortase (surface protein transpeptidase)
SAV_RS13810	COG1760	l-serine dehydratase
SAV_RS13815	COG1760	l-serine dehydratase
SAV_RS13830	COG0697	spore germination
SAV_RS13835	COG0657	acetylesterase activity
SAV_RS13855	COG0028	Belongs to the TPP enzyme family
SAV_RS13870	COG0583	DNA-binding transcription factor activity
SAV_RS13880	COG3942	CHAP domain
SAV_RS13890	COG3425	synthase
SAV_RS13895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SAV_RS13920	COG2409	Drug exporters of the RND superfamily
SAV_RS13965	COG0436	Aminotransferase
SAV_RS13995	COG3942	CHAP domain
SAV_RS14000	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAV_RS14000	COG2755	lipolytic protein G-D-S-L family
SAV_RS14110	COG3001	Fructosamine kinase
SAV_RS14115	COG0167	dihydroorotate dehydrogenase activity
SAV_RS14175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAV_RS14180	COG3527	Alpha-acetolactate decarboxylase
SAV_RS14195	COG0531	amino acid
SAV_RS14225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAV_RS14245	COG1012	belongs to the aldehyde dehydrogenase family
SAV_RS14255	COG1510	regulation of RNA biosynthetic process
SAV_RS14260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAV_RS14285	COG2851	Citrate transporter
SAV_RS14300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SAV_RS14310	COG0386	Belongs to the glutathione peroxidase family
SAV_RS14335	COG1136	(ABC) transporter
SAV_RS14340	COG2205	protein histidine kinase activity
SAV_RS14345	COG0745	RESPONSE REGULATOR receiver
SAV_RS14360	COG1785	Belongs to the alkaline phosphatase family
SAV_RS14365	COG1846	Transcriptional regulator
SAV_RS14410	COG1438	arginine binding
SAV_RS14430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAV_RS14430	COG3711	transcriptional antiterminator
SAV_RS14435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAV_RS14435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAV_RS14435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAV_RS14440	COG1482	cell wall glycoprotein biosynthetic process
SAV_RS14450	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAV_RS14450	COG3942	CHAP domain
SAV_RS14455	COG3433	isochorismatase activity
SAV_RS14455	COG1535	isochorismatase
SAV_RS14470	COG0438	transferase activity, transferring glycosyl groups
SAV_RS14485	COG1073	alpha beta
SAV_RS14505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAV_RS14525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAV_RS14615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SAV_RS14705	COG2962	Rard protein
SAV_RS14715	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SAV_RS14730	COG1136	(ABC) transporter
SAV_RS14735	COG0577	efflux transmembrane transporter activity
SAV_RS14745	COG1278	Cold shock
SAV_RS14765	COG1475	DNA binding