locus-tag	class	description
SA_RS00100	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SA_RS00155	COG2501	S4 domain
SA_RS00175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SA_RS00200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SA_RS00210	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SA_RS00220	COG0305	Participates in initiation and elongation during chromosome replication
SA_RS00250	COG4863	YycH protein
SA_RS00260	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SA_RS00265	COG0737	Belongs to the 5'-nucleotidase family
SA_RS00325	COG0584	glycerophosphoryl diester phosphodiesterase
SA_RS00330	COG2030	dehydratase
SA_RS00350	COG1846	Transcriptional regulator
SA_RS00350	COG1940	carbohydrate kinase activity
SA_RS00360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA_RS00365	COG2210	Belongs to the sulfur carrier protein TusA family
SA_RS00370	COG1937	Protein conserved in bacteria
SA_RS00375	COG0730	response to heat
SA_RS00380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SA_RS00410	COG2003	Belongs to the UPF0758 family
SA_RS00455	COG2801	Transposase and inactivated derivatives
SA_RS00470	COG1288	antiporter activity
SA_RS00475	COG0745	RESPONSE REGULATOR receiver
SA_RS00480	COG2205	protein histidine kinase activity
SA_RS00555	COG0730	response to heat
SA_RS00560	COG1937	Protein conserved in bacteria
SA_RS00565	COG2210	Belongs to the sulfur carrier protein TusA family
SA_RS00570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA_RS00615	COG0823	Involved in the tonB-independent uptake of proteins
SA_RS00650	COG1473	amidohydrolase
SA_RS00660	COG1283	sodium-dependent phosphate transmembrane transporter activity
SA_RS00665	COG4716	Myosin-crossreactive antigen
SA_RS00670	COG0697	spore germination
SA_RS00685	COG1620	l-lactate permease
SA_RS00700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA_RS00705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA_RS00710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SA_RS00720	COG2423	ornithine cyclodeaminase activity
SA_RS00725	COG4264	IucA IucC family
SA_RS00730	COG2814	Major facilitator Superfamily
SA_RS00735	COG4264	IucA IucC family
SA_RS00740	COG4264	IucA IucC family
SA_RS00750	COG0019	diaminopimelate decarboxylase activity
SA_RS00755	COG1475	DNA binding
SA_RS00780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SA_RS00785	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SA_RS00790	COG0438	transferase activity, transferring glycosyl groups
SA_RS00825	COG0813	purine-nucleoside phosphorylase activity
SA_RS00830	COG2814	Major facilitator Superfamily
SA_RS00850	COG3639	organic phosphonate transmembrane transporter activity
SA_RS00870	COG0737	Belongs to the 5'-nucleotidase family
SA_RS00885	COG1012	belongs to the aldehyde dehydrogenase family
SA_RS00885	COG1454	alcohol dehydrogenase
SA_RS00910	COG1086	Polysaccharide biosynthesis protein
SA_RS00920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SA_RS00950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SA_RS00960	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SA_RS00965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SA_RS00975	COG2832	Protein of unknown function (DUF454)
SA_RS01015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SA_RS01020	COG1960	acyl-CoA dehydrogenase activity
SA_RS01025	COG5609	conserved protein (DUF2294)
SA_RS01075	COG1114	Component of the transport system for branched-chain amino acids
SA_RS01080	COG1335	isochorismatase
SA_RS01085	COG3961	Belongs to the TPP enzyme family
SA_RS01115	COG1737	Transcriptional regulator
SA_RS01140	COG1136	(ABC) transporter
SA_RS01145	COG1136	(ABC) transporter
SA_RS01145	COG0577	efflux transmembrane transporter activity
SA_RS01165	COG1131	(ABC) transporter
SA_RS01180	COG0601	transmembrane transport
SA_RS01185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA_RS01195	COG0405	Gamma-glutamyltransferase
SA_RS01215	COG3842	ATPase activity
SA_RS01225	COG1175	transmembrane transport
SA_RS01230	COG3833	ABC-type maltose transport systems, permease component
SA_RS01235	COG0673	inositol 2-dehydrogenase activity
SA_RS01240	COG0673	inositol 2-dehydrogenase activity
SA_RS01250	COG1755	Isoprenylcysteine carboxyl methyltransferase
SA_RS01310	COG0183	Belongs to the thiolase family
SA_RS01320	COG1960	acyl-CoA dehydrogenase activity
SA_RS01325	COG0318	PFAM AMP-dependent synthetase and ligase
SA_RS01340	COG0747	negative chemotaxis
SA_RS01345	COG3189	MarR family transcriptional regulator
SA_RS01375	COG2190	(PTS) system
SA_RS01375	COG1263	PTS System
SA_RS01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA_RS01380	COG1957	nucleoside hydrolase
SA_RS01400	COG3414	Phosphotransferase system galactitol-specific IIB component
SA_RS01405	COG3775	system Galactitol-specific IIC component
SA_RS01410	COG1063	alcohol dehydrogenase
SA_RS01420	COG1063	alcohol dehydrogenase
SA_RS01430	COG1063	alcohol dehydrogenase
SA_RS01435	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA_RS01440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA_RS01450	COG1063	alcohol dehydrogenase
SA_RS01455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA_RS01490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SA_RS01495	COG1263	PTS System
SA_RS01495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA_RS01495	COG2190	(PTS) system
SA_RS01500	COG2723	6-phospho-beta-galactosidase activity
SA_RS01510	COG2226	methyltransferase
SA_RS01565	COG1131	(ABC) transporter
SA_RS01585	COG3942	CHAP domain
SA_RS01585	COG1388	LysM domain
SA_RS01705	COG1114	Component of the transport system for branched-chain amino acids
SA_RS01710	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SA_RS01720	COG0577	efflux transmembrane transporter activity
SA_RS01745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SA_RS01750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SA_RS01775	COG3314	Sporulation integral membrane protein YlbJ
SA_RS01800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SA_RS01830	COG3037	sugar-specific permease SgaT UlaA
SA_RS01840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA_RS01845	COG3711	transcriptional antiterminator
SA_RS01865	COG2271	Major facilitator Superfamily
SA_RS01870	COG0346	lactoylglutathione lyase activity
SA_RS01875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SA_RS01880	COG0431	NADPH-dependent FMN reductase
SA_RS01895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SA_RS01900	COG2822	iron ion transport
SA_RS01910	COG0672	)-iron permease
SA_RS01915	COG0805	protein transport
SA_RS01920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SA_RS01930	COG1476	TRANSCRIPTIONal
SA_RS01940	COG1131	(ABC) transporter
SA_RS01975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SA_RS01975	COG0646	methionine synthase
SA_RS01980	COG0626	cystathionine gamma-synthase activity
SA_RS01985	COG0626	cystathionine gamma-synthase activity
SA_RS01990	COG1475	DNA binding
SA_RS01995	COG0668	transmembrane transport
SA_RS02000	COG4481	Protein conserved in bacteria
SA_RS02005	COG0012	GTP binding
SA_RS02105	COG1823	symporter activity
SA_RS02140	COG2233	PERMEase
SA_RS02175	COG3759	membrane
SA_RS02340	COG0523	cobalamin synthesis protein
SA_RS02350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SA_RS02360	COG5609	conserved protein (DUF2294)
SA_RS02375	COG1647	Serine aminopeptidase, S33
SA_RS02380	COG0733	neurotransmitter:sodium symporter activity
SA_RS02385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SA_RS02390	COG0626	cystathionine gamma-synthase activity
SA_RS02400	COG2011	ABC-type metal ion transport system permease component
SA_RS02405	COG1464	Belongs to the NlpA lipoprotein family
SA_RS02440	COG0583	DNA-binding transcription factor activity
SA_RS02445	COG0070	glutamate synthase
SA_RS02445	COG0067	glutamate synthase
SA_RS02445	COG0069	glutamate synthase activity
SA_RS02450	COG0493	'glutamate synthase
SA_RS02460	COG1263	PTS System
SA_RS02460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA_RS02465	COG0366	Alpha amylase catalytic
SA_RS02470	COG2188	Transcriptional regulator
SA_RS02485	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SA_RS02530	COG1982	Orn Lys Arg decarboxylase major
SA_RS02540	COG3870	Protein conserved in bacteria
SA_RS02550	COG0470	DNA polymerase III
SA_RS02555	COG1774	PSP1 C-terminal conserved region
SA_RS02565	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SA_RS02575	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SA_RS02590	COG0084	hydrolase, TatD family'
SA_RS02595	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SA_RS02605	COG4466	Protein conserved in bacteria
SA_RS02615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SA_RS02620	COG0251	oxidation-reduction process
SA_RS02665	COG2244	polysaccharide biosynthetic process
SA_RS02670	COG3956	TIGRFAM MazG family protein
SA_RS02675	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SA_RS02685	COG1098	S1 RNA binding domain
SA_RS02700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SA_RS02725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SA_RS02805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SA_RS02820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SA_RS02830	COG3880	PFAM UvrB UvrC protein
SA_RS02850	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SA_RS02855	COG4956	integral membrane protein (PIN domain superfamily)
SA_RS02875	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SA_RS02925	COG2813	Specifically methylates the guanine in position
SA_RS02965	COG1473	amidohydrolase
SA_RS02995	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SA_RS03000	COG1428	Deoxynucleoside kinase
SA_RS03005	COG1428	Deoxynucleoside kinase
SA_RS03015	COG0561	phosphatase activity
SA_RS03055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SA_RS03070	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SA_RS03160	COG0095	Lipoate-protein ligase
SA_RS03165	COG0083	homoserine kinase activity
SA_RS03185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SA_RS03220	COG0667	Aldo Keto reductase
SA_RS03230	COG0655	NAD(P)H dehydrogenase (quinone) activity
SA_RS03240	COG1078	dGTPase activity
SA_RS03275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SA_RS03280	COG4139	cobalamin transport
SA_RS03330	COG4974	Belongs to the 'phage' integrase family
SA_RS03380	COG0803	Belongs to the bacterial solute-binding protein 9 family
SA_RS03385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SA_RS03390	COG1121	(ABC) transporter
SA_RS03395	COG1321	iron dependent repressor
SA_RS03405	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SA_RS03415	COG1682	transport, permease protein
SA_RS03420	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA_RS03430	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SA_RS03435	COG1686	Belongs to the peptidase S11 family
SA_RS03440	COG1132	(ABC) transporter
SA_RS03445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SA_RS03455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SA_RS03460	COG1120	ATPase activity
SA_RS03465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA_RS03470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA_RS03475	COG2376	Dihydroxyacetone kinase
SA_RS03485	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SA_RS03495	COG3949	Membrane
SA_RS03520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SA_RS03535	COG1136	(ABC) transporter
SA_RS03540	COG0577	efflux transmembrane transporter activity
SA_RS03545	COG1392	Phosphate transport regulator
SA_RS03550	COG0306	phosphate transporter
SA_RS03555	COG3942	CHAP domain
SA_RS03555	COG1388	LysM domain
SA_RS03565	COG4977	sequence-specific DNA binding
SA_RS03565	COG1917	Cupin 2, conserved barrel domain protein
SA_RS03595	COG0583	DNA-binding transcription factor activity
SA_RS03600	COG2814	Major facilitator Superfamily
SA_RS03605	COG2839	Protein conserved in bacteria
SA_RS03635	COG1611	Belongs to the LOG family
SA_RS03655	COG4988	ABC transporter
SA_RS03660	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SA_RS03670	COG0523	cobalamin synthesis protein
SA_RS03675	COG4989	oxidoreductase activity
SA_RS03685	COG0471	metal ion transport
SA_RS03690	COG0415	Belongs to the DNA photolyase family
SA_RS03720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SA_RS03725	COG1349	DNA-binding transcription factor activity
SA_RS03730	COG1105	Belongs to the carbohydrate kinase PfkB family
SA_RS03735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA_RS03735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA_RS03735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA_RS03745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SA_RS03750	COG1253	flavin adenine dinucleotide binding
SA_RS03755	COG0656	L-ascorbic acid biosynthetic process
SA_RS03760	COG0463	Glycosyl transferase, family 2
SA_RS03795	COG0720	synthase
SA_RS03805	COG0512	Glutamine amidotransferase of anthranilate synthase
SA_RS03805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SA_RS03810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SA_RS03845	COG0488	(ABC) transporter
SA_RS03850	COG0514	ATP-dependent DNA helicase (RecQ)
SA_RS03855	COG1125	glycine betaine transport
SA_RS03855	COG0517	IMP dehydrogenase activity
SA_RS03860	COG1174	glycine betaine transport
SA_RS03890	COG3104	oligopeptide transport
SA_RS03910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SA_RS03915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SA_RS03925	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA_RS03930	COG4605	iron ion homeostasis
SA_RS03935	COG4604	ABC transporter, ATP-binding protein
SA_RS03940	COG4607	ABC-type enterochelin transport system periplasmic component
SA_RS03995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SA_RS04000	COG1739	Uncharacterized protein family UPF0029
SA_RS04010	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SA_RS04015	COG1040	competence protein
SA_RS04045	COG1388	LysM domain
SA_RS04045	COG3942	CHAP domain
SA_RS04105	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SA_RS04170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SA_RS04175	COG1647	Serine aminopeptidase, S33
SA_RS04180	COG0557	exoribonuclease II activity
SA_RS04250	COG1278	Cold shock
SA_RS04290	COG0406	alpha-ribazole phosphatase activity
SA_RS04295	COG1279	arginine transmembrane transporter activity
SA_RS04320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SA_RS04325	COG1393	Belongs to the ArsC family
SA_RS04340	COG3878	Protein conserved in bacteria
SA_RS04370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SA_RS04385	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SA_RS04400	COG2011	ABC-type metal ion transport system permease component
SA_RS04405	COG1464	Belongs to the NlpA lipoprotein family
SA_RS04420	COG0396	ATPase activity
SA_RS04425	COG0719	Fe-S assembly protein
SA_RS04435	COG0822	iron-sulfur transferase activity
SA_RS04455	COG1253	flavin adenine dinucleotide binding
SA_RS04470	COG1801	Protein of unknown function DUF72
SA_RS04475	COG0730	response to heat
SA_RS04490	COG4470	Protein conserved in bacteria
SA_RS04505	COG2445	Protein of unknown function DUF86
SA_RS04535	COG1696	Membrane protein involved in D-alanine export
SA_RS04545	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SA_RS04550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SA_RS04555	COG4837	Protein of unknown function (DUF1462)
SA_RS04560	COG1252	NADH dehydrogenase
SA_RS04570	COG0316	Belongs to the HesB IscA family
SA_RS04580	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SA_RS04585	COG2056	Na+-H+ antiporter family
SA_RS04590	COG2050	protein possibly involved in aromatic compounds catabolism
SA_RS04645	COG1098	S1 RNA binding domain
SA_RS04650	COG1902	pentaerythritol trinitrate reductase activity
SA_RS04665	COG0584	glycerophosphoryl diester phosphodiesterase
SA_RS04685	COG0398	Pfam SNARE associated Golgi protein
SA_RS04725	COG0561	phosphatase activity
SA_RS04750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SA_RS04765	COG1881	PFAM PEBP family protein
SA_RS04795	COG0601	transmembrane transport
SA_RS04800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA_RS04805	COG0444	Belongs to the ABC transporter superfamily
SA_RS04810	COG4608	Belongs to the ABC transporter superfamily
SA_RS04815	COG4166	transmembrane transport
SA_RS04820	COG0747	negative chemotaxis
SA_RS04825	COG0444	Belongs to the ABC transporter superfamily
SA_RS04830	COG4608	Belongs to the ABC transporter superfamily
SA_RS04835	COG0601	transmembrane transport
SA_RS04840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA_RS04865	COG1164	Oligoendopeptidase f
SA_RS04875	COG2346	COG2346, Truncated hemoglobins
SA_RS04890	COG2357	RelA SpoT domain protein
SA_RS04900	COG0564	pseudouridine synthase activity
SA_RS04905	COG2239	Acts as a magnesium transporter
SA_RS04910	COG0569	domain protein
SA_RS04910	COG0475	glutathione-regulated potassium exporter activity
SA_RS04920	COG0628	permease
SA_RS04925	COG1115	amino acid carrier protein
SA_RS04965	COG0861	Integral membrane protein TerC family
SA_RS04975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SA_RS04980	COG0737	Belongs to the 5'-nucleotidase family
SA_RS04995	COG4903	ComK protein
SA_RS05010	COG4873	Protein conserved in bacteria
SA_RS05055	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SA_RS05065	COG2314	TM2 domain
SA_RS05070	COG0456	acetyltransferase
SA_RS05075	COG1575	Belongs to the MenA family. Type 1 subfamily
SA_RS05080	COG1169	isochorismate synthase
SA_RS05090	COG2267	carboxylic ester hydrolase activity
SA_RS05115	COG0436	Aminotransferase
SA_RS05120	COG3594	Acyltransferase
SA_RS05150	COG1316	TRANSCRIPTIONal
SA_RS05195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SA_RS05210	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SA_RS05250	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SA_RS05255	COG4172	Belongs to the ABC transporter superfamily
SA_RS05260	COG4721	ABC-type cobalt transport system, permease component
SA_RS05285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SA_RS05305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SA_RS05310	COG1271	oxidase subunit
SA_RS05315	COG1294	oxidase, subunit
SA_RS05320	COG0569	domain protein
SA_RS05385	COG1176	ABC-type spermidine putrescine transport system, permease component I
SA_RS05390	COG1177	transmembrane transport
SA_RS05395	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SA_RS05420	COG0483	inositol monophosphate 1-phosphatase activity
SA_RS05430	COG1217	gtp-binding protein TYPA
SA_RS05440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SA_RS05450	COG0772	Belongs to the SEDS family
SA_RS05485	COG3679	Belongs to the UPF0342 family
SA_RS05505	COG0742	ribosomal rna small subunit methyltransferase
SA_RS05565	COG4509	Sortase family
SA_RS05580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SA_RS05610	COG1796	DNA polymerase
SA_RS05610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SA_RS05635	COG2009	succinate dehydrogenase
SA_RS05640	COG1053	succinate dehydrogenase
SA_RS05645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SA_RS05770	COG1288	antiporter activity
SA_RS05805	COG1011	Hydrolase
SA_RS05830	COG4839	cell division protein FtsL
SA_RS05835	COG0768	penicillin binding
SA_RS05850	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SA_RS05855	COG0849	cell division
SA_RS05870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SA_RS05880	COG0762	integral membrane protein
SA_RS05885	COG2302	S4 RNA-binding domain
SA_RS05890	COG3599	regulation of cell shape
SA_RS05900	COG2514	catechol 2,3-dioxygenase activity
SA_RS05915	COG0564	pseudouridine synthase activity
SA_RS05925	COG2233	PERMEase
SA_RS05970	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SA_RS05985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SA_RS05990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SA_RS06000	COG2314	TM2 domain
SA_RS06015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SA_RS06015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SA_RS06025	COG0631	protein serine/threonine phosphatase activity
SA_RS06040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SA_RS06055	COG1302	Protein conserved in bacteria
SA_RS06105	COG1196	nuclear chromosome segregation
SA_RS06110	COG0552	protein localization to endoplasmic reticulum
SA_RS06120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SA_RS06180	COG2348	transferase activity, transferring amino-acyl groups
SA_RS06185	COG0758	DNA mediated transformation
SA_RS06280	COG0195	Participates in both transcription termination and antitermination
SA_RS06285	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SA_RS06310	COG0196	riboflavin kinase activity
SA_RS06335	COG2188	Transcriptional regulator
SA_RS06340	COG0612	Peptidase, M16
SA_RS06345	COG0612	Peptidase, M16
SA_RS06350	COG0300	oxidoreductase activity
SA_RS06370	COG1058	Belongs to the CinA family
SA_RS06370	COG1546	Belongs to the CinA family
SA_RS06390	COG1692	metallophosphoesterase
SA_RS06395	COG0674	pyruvate-flavodoxin oxidoreductase activity
SA_RS06395	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SA_RS06400	COG1013	pyruvate-flavodoxin oxidoreductase activity
SA_RS06435	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SA_RS06440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SA_RS06465	COG1923	regulation of RNA biosynthetic process
SA_RS06475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SA_RS06480	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SA_RS06485	COG0789	Transcriptional regulator
SA_RS06565	COG1131	(ABC) transporter
SA_RS06580	COG2197	response regulator
SA_RS06590	COG1525	nuclease
SA_RS06605	COG0527	aspartate kinase activity
SA_RS06610	COG0460	homoserine dehydrogenase
SA_RS06615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SA_RS06640	COG0833	amino acid
SA_RS06670	COG2340	Cysteine-rich secretory protein family
SA_RS06705	COG4846	Membrane protein involved in cytochrome C biogenesis
SA_RS06725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SA_RS06735	COG0824	Thioesterase
SA_RS06765	COG1115	amino acid carrier protein
SA_RS06780	COG0628	permease
SA_RS06805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SA_RS06815	COG1363	Peptidase, m42
SA_RS06820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SA_RS06825	COG0512	Glutamine amidotransferase of anthranilate synthase
SA_RS06870	COG0561	phosphatase activity
SA_RS06915	COG0704	Plays a role in the regulation of phosphate uptake
SA_RS06925	COG0581	inorganic phosphate transmembrane transporter activity
SA_RS06930	COG0573	inorganic phosphate transmembrane transporter activity
SA_RS06955	COG0488	(ABC) transporter
SA_RS06960	COG0527	aspartate kinase activity
SA_RS06965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SA_RS07040	COG4548	von Willebrand factor, type A
SA_RS07045	COG0714	Associated with various cellular activities
SA_RS07090	COG0671	phosphoesterase, PA-phosphatase related
SA_RS07170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SA_RS07200	COG0531	amino acid
SA_RS07215	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA_RS07220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SA_RS07240	COG0116	Belongs to the methyltransferase superfamily
SA_RS07270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SA_RS07270	COG4499	WXG100 protein secretion system (Wss), protein YukC
SA_RS07280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SA_RS07285	COG3935	DnaD domain protein
SA_RS07310	COG0438	transferase activity, transferring glycosyl groups
SA_RS07315	COG1694	Mazg nucleotide pyrophosphohydrolase
SA_RS07320	COG2738	Putative neutral zinc metallopeptidase
SA_RS07325	COG4347	Protein of unknown function (DUF1405)
SA_RS07365	COG0142	geranyltranstransferase activity
SA_RS07430	COG0492	ferredoxin-NADP+ reductase activity
SA_RS07445	COG0514	ATP-dependent DNA helicase (RecQ)
SA_RS07455	COG1141	Ferredoxin
SA_RS07505	COG0745	RESPONSE REGULATOR receiver
SA_RS07510	COG1187	pseudouridine synthase activity
SA_RS07535	COG0735	belongs to the Fur family
SA_RS07540	COG0494	nUDIX hydrolase
SA_RS07545	COG0667	Aldo Keto reductase
SA_RS07555	COG4221	oxidoreductase activity
SA_RS07570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SA_RS07580	COG0366	Alpha amylase catalytic
SA_RS07585	COG1609	Transcriptional regulator
SA_RS07610	COG2195	Cleaves the N-terminal amino acid of tripeptides
SA_RS07620	COG4129	membrane
SA_RS07630	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA_RS07635	COG0022	dehydrogenase e1 component
SA_RS07640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SA_RS07645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SA_RS07650	COG0497	DNA recombination
SA_RS07680	COG1302	Protein conserved in bacteria
SA_RS07685	COG0439	Biotin carboxylase
SA_RS07690	COG0511	ligase activity, forming carbon-carbon bonds
SA_RS07700	COG0006	proline dipeptidase activity
SA_RS07715	COG0095	Lipoate-protein ligase
SA_RS07720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SA_RS07765	COG4537	Required for transformation and DNA binding
SA_RS07770	COG1459	type II secretion system
SA_RS07775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SA_RS07780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA_RS07785	COG0011	TIGRFAM Protein of
SA_RS07790	COG1940	carbohydrate kinase activity
SA_RS07795	COG4483	Protein conserved in bacteria
SA_RS07805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SA_RS07815	COG0768	penicillin binding
SA_RS07830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SA_RS07835	COG1121	(ABC) transporter
SA_RS07845	COG0513	Belongs to the DEAD box helicase family
SA_RS07855	COG2384	SAM-dependent methyltransferase
SA_RS07875	COG0517	IMP dehydrogenase activity
SA_RS07895	COG0295	cytidine deaminase activity
SA_RS07910	COG1702	phosphate starvation-inducible protein PhoH
SA_RS07925	COG1030	water channel activity
SA_RS07935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SA_RS07940	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SA_RS07970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SA_RS07990	COG1466	dna polymerase III delta subunit
SA_RS07995	COG0658	competence protein
SA_RS07995	COG2333	competence protein COMEC
SA_RS08000	COG2131	deaminase
SA_RS08005	COG2183	response to ionizing radiation
SA_RS08010	COG2226	methyltransferase
SA_RS08015	COG0799	negative regulation of ribosome biogenesis
SA_RS08020	COG1713	HD superfamily hydrolase involved in NAD metabolism
SA_RS08030	COG1534	Rna-binding protein
SA_RS08040	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SA_RS08045	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SA_RS08075	COG3177	Filamentation induced by cAMP protein fic
SA_RS08080	COG1914	H( )-stimulated, divalent metal cation uptake system
SA_RS08090	COG0439	Biotin carboxylase
SA_RS08095	COG0511	ligase activity, forming carbon-carbon bonds
SA_RS08100	COG1984	allophanate hydrolase subunit 2
SA_RS08105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SA_RS08120	COG0826	peptidase U32
SA_RS08125	COG0826	peptidase U32
SA_RS08155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SA_RS08170	COG1104	cysteine desulfurase activity
SA_RS08175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SA_RS08185	COG3237	CsbD-like
SA_RS08190	COG1959	2 iron, 2 sulfur cluster binding
SA_RS08195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SA_RS08200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SA_RS08240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SA_RS08240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SA_RS08245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SA_RS08245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SA_RS08250	COG1862	Preprotein translocase
SA_RS08290	COG2868	ribosomal protein
SA_RS08325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SA_RS08360	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SA_RS08370	COG0285	dihydrofolate synthase activity
SA_RS08380	COG2818	Glycosylase
SA_RS08415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SA_RS08450	COG4112	unkown
SA_RS08475	COG0833	amino acid
SA_RS08490	COG1484	DNA-dependent DNA replication
SA_RS08520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA_RS08520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA_RS08530	COG5002	protein histidine kinase activity
SA_RS08535	COG0745	RESPONSE REGULATOR receiver
SA_RS08550	COG0372	Belongs to the citrate synthase family
SA_RS08555	COG1113	amino acid transport
SA_RS08580	COG0281	malic enzyme
SA_RS08590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SA_RS08595	COG4109	DRTGG domain
SA_RS08635	COG0827	DNA restriction-modification system
SA_RS08645	COG0730	response to heat
SA_RS08655	COG1104	cysteine desulfurase activity
SA_RS08670	COG1956	GAF domain-containing protein
SA_RS08690	COG0584	glycerophosphoryl diester phosphodiesterase
SA_RS08695	COG1764	response to oxidative stress
SA_RS08700	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SA_RS08705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SA_RS08720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA_RS08720	COG1263	PTS System
SA_RS08725	COG0204	Acyl-transferase
SA_RS08730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SA_RS08765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA_RS08770	COG0454	-acetyltransferase
SA_RS08790	COG1605	Chorismate mutase
SA_RS08790	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SA_RS08815	COG1674	ftsk spoiiie
SA_RS08820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SA_RS08830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SA_RS08835	COG1363	Peptidase, m42
SA_RS08845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA_RS08855	COG0510	thiamine kinase activity
SA_RS08875	COG1187	pseudouridine synthase activity
SA_RS08880	COG2244	polysaccharide biosynthetic process
SA_RS08885	COG2081	HI0933 family
SA_RS08905	COG2814	Major facilitator Superfamily
SA_RS08910	COG1242	4 iron, 4 sulfur cluster binding
SA_RS08915	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SA_RS08925	COG2267	carboxylic ester hydrolase activity
SA_RS08955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SA_RS08955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SA_RS08975	COG5632	N-Acetylmuramoyl-L-alanine amidase
SA_RS08975	COG4193	domain, Protein
SA_RS08975	COG3266	domain, Protein
SA_RS09005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SA_RS09045	COG0656	L-ascorbic acid biosynthetic process
SA_RS09065	COG1506	peptidase
SA_RS09070	COG2816	NAD+ diphosphatase activity
SA_RS09325	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SA_RS09355	COG1131	(ABC) transporter
SA_RS09360	COG0537	adenosine 5'-monophosphoramidase activity
SA_RS09390	COG0420	3'-5' exonuclease activity
SA_RS09415	COG2197	response regulator
SA_RS09420	COG2203	Gaf domain
SA_RS09420	COG4585	Histidine kinase
SA_RS09425	COG0564	pseudouridine synthase activity
SA_RS09455	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SA_RS09460	COG1126	abc transporter atp-binding protein
SA_RS09465	COG0765	amino acid transport
SA_RS09635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SA_RS09640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SA_RS09650	COG4129	membrane
SA_RS09675	COG1988	membrane-bound metal-dependent
SA_RS09690	COG1134	teichoic acid transport
SA_RS09690	COG1388	LysM domain
SA_RS09720	COG0535	radical SAM domain protein
SA_RS09725	COG1607	acyl-coa hydrolase
SA_RS09730	COG2309	aminopeptidase activity
SA_RS09750	COG1295	ribonuclease BN
SA_RS09870	COG4851	CamS sex pheromone cAM373 precursor
SA_RS09890	COG4496	protein, YerC YecD
SA_RS09925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SA_RS09935	COG0077	Prephenate dehydratase
SA_RS09945	COG0471	metal ion transport
SA_RS09955	COG1335	isochorismatase
SA_RS09970	COG1012	belongs to the aldehyde dehydrogenase family
SA_RS10020	COG1131	(ABC) transporter
SA_RS10035	COG1725	Transcriptional regulator
SA_RS10105	COG5632	N-Acetylmuramoyl-L-alanine amidase
SA_RS10105	COG1388	LysM domain
SA_RS10155	COG0739	heme binding
SA_RS10205	COG0740	serine-type endopeptidase activity
SA_RS10370	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SA_RS10425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SA_RS10450	COG3728	DNA packaging
SA_RS10450	COG5484	DNA packaging
SA_RS10530	COG0582	viral genome integration into host DNA
SA_RS10595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SA_RS10600	COG1621	beta-fructofuranosidase activity
SA_RS10605	COG1609	Transcriptional regulator
SA_RS10610	COG0004	ammonium transporteR
SA_RS10615	COG0425	Belongs to the sulfur carrier protein TusA family
SA_RS10620	COG2391	methyltransferase activity
SA_RS10630	COG0488	(ABC) transporter
SA_RS10640	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SA_RS10650	COG0456	acetyltransferase
SA_RS10655	COG1214	PFAM Peptidase M22, glycoprotease
SA_RS10660	COG0802	atpase or kinase
SA_RS10675	COG0028	Belongs to the TPP enzyme family
SA_RS10745	COG2183	response to ionizing radiation
SA_RS10750	COG1191	sigma factor activity
SA_RS10760	COG1366	Belongs to the anti-sigma-factor antagonist family
SA_RS10765	COG2208	phosphoserine phosphatase activity
SA_RS10800	COG3428	Bacterial PH domain
SA_RS10830	COG2205	protein histidine kinase activity
SA_RS10835	COG0745	RESPONSE REGULATOR receiver
SA_RS10850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SA_RS10860	COG0772	Belongs to the SEDS family
SA_RS10875	COG1937	Protein conserved in bacteria
SA_RS10885	COG1418	mRNA catabolic process
SA_RS10930	COG0629	single-stranded DNA binding
SA_RS11005	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SA_RS11030	COG0009	L-threonylcarbamoyladenylate synthase
SA_RS11035	COG2890	protein-(glutamine-N5) methyltransferase activity
SA_RS11055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SA_RS11095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SA_RS11145	COG0813	purine-nucleoside phosphorylase activity
SA_RS11150	COG0783	Belongs to the Dps family
SA_RS11170	COG1482	cell wall glycoprotein biosynthetic process
SA_RS11175	COG0702	epimerase
SA_RS11180	COG0640	Transcriptional regulator
SA_RS11195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SA_RS11235	COG0561	phosphatase activity
SA_RS11240	COG1119	ATPase activity
SA_RS11255	COG3711	transcriptional antiterminator
SA_RS11285	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SA_RS11345	COG0489	protein tyrosine kinase activity
SA_RS11350	COG2814	Major facilitator Superfamily
SA_RS11365	COG1272	protein, Hemolysin III
SA_RS11375	COG1988	membrane-bound metal-dependent
SA_RS11385	COG3314	Sporulation integral membrane protein YlbJ
SA_RS11390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA_RS11395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA_RS11400	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SA_RS11410	COG3457	Alanine racemase
SA_RS11415	COG4264	IucA IucC family
SA_RS11420	COG2814	Major facilitator Superfamily
SA_RS11445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SA_RS11455	COG2130	NADP-dependent
SA_RS11520	COG0656	L-ascorbic acid biosynthetic process
SA_RS11525	COG0789	Transcriptional regulator
SA_RS11535	COG5492	domain, Protein
SA_RS11555	COG3527	Alpha-acetolactate decarboxylase
SA_RS11560	COG0028	Belongs to the TPP enzyme family
SA_RS11665	COG0201	protein transport
SA_RS11780	COG2252	PERMEase
SA_RS11825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SA_RS11890	COG1763	Mo-molybdopterin cofactor biosynthetic process
SA_RS11910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SA_RS11915	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SA_RS11920	COG4149	molybdate abc transporter
SA_RS11925	COG0725	ABC transporter, periplasmic molybdate-binding protein
SA_RS11940	COG1268	BioY protein
SA_RS11955	COG1960	acyl-CoA dehydrogenase activity
SA_RS11960	COG4413	Urea transporter
SA_RS12025	COG3942	CHAP domain
SA_RS12035	COG1757	Na H antiporter
SA_RS12050	COG3942	CHAP domain
SA_RS12120	COG1113	amino acid transport
SA_RS12140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SA_RS12145	COG0385	Bile acid
SA_RS12155	COG1263	PTS System
SA_RS12155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA_RS12160	COG1737	Transcriptional regulator
SA_RS12180	COG1028	Short-chain dehydrogenase reductase Sdr
SA_RS12185	COG1473	amidohydrolase
SA_RS12200	COG0583	DNA-binding transcription factor activity
SA_RS12225	COG2258	MOSC domain
SA_RS12245	COG1668	transmembrane transport
SA_RS12250	COG4152	abc transporter atp-binding protein
SA_RS12255	COG3152	Membrane
SA_RS12265	COG0786	glutamate:sodium symporter activity
SA_RS12275	COG0598	Magnesium transport protein CorA
SA_RS12290	COG0657	acetylesterase activity
SA_RS12300	COG2814	Major facilitator Superfamily
SA_RS12305	COG1566	PFAM secretion protein HlyD family protein
SA_RS12315	COG2814	Major facilitator Superfamily
SA_RS12380	COG1620	l-lactate permease
SA_RS12400	COG0604	alcohol dehydrogenase
SA_RS12430	COG1511	domain protein
SA_RS12445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA_RS12445	COG1263	PTS System
SA_RS12460	COG3871	stress protein (general stress protein 26)
SA_RS12500	COG0789	Transcriptional regulator
SA_RS12520	COG2181	nitrate reductase activity
SA_RS12530	COG1140	nitrate reductase beta subunit
SA_RS12535	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SA_RS12545	COG2146	nitrite reductase [NAD(P)H] activity
SA_RS12550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SA_RS12560	COG0454	-acetyltransferase
SA_RS12565	COG2116	formate transmembrane transporter activity
SA_RS12580	COG0803	Belongs to the bacterial solute-binding protein 9 family
SA_RS12580	COG3443	Belongs to the bacterial solute-binding protein 9 family
SA_RS12615	COG1126	abc transporter atp-binding protein
SA_RS12620	COG0765	amino acid transport
SA_RS12625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SA_RS12630	COG2814	Major facilitator Superfamily
SA_RS12650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SA_RS12695	COG0156	8-amino-7-oxononanoate synthase activity
SA_RS12705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SA_RS12710	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SA_RS12725	COG1132	(ABC) transporter
SA_RS12730	COG2375	cellular response to nickel ion
SA_RS12730	COG1132	(ABC) transporter
SA_RS12750	COG1929	Belongs to the glycerate kinase type-1 family
SA_RS12760	COG2814	Major facilitator Superfamily
SA_RS12795	COG0531	amino acid
SA_RS12820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SA_RS12830	COG1174	glycine betaine transport
SA_RS12840	COG1174	glycine betaine transport
SA_RS12860	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SA_RS12865	COG0531	amino acid
SA_RS12870	COG2272	Belongs to the type-B carboxylesterase lipase family
SA_RS12875	COG2814	Major facilitator Superfamily
SA_RS12880	COG0390	transport system, permease component
SA_RS12885	COG4619	ABC transporter
SA_RS12890	COG1363	Peptidase, m42
SA_RS12910	COG4808	Protein conserved in bacteria
SA_RS12915	COG0069	glutamate synthase activity
SA_RS12970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SA_RS12975	COG1028	Short-chain dehydrogenase reductase Sdr
SA_RS12980	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SA_RS12985	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SA_RS13070	COG0494	nUDIX hydrolase
SA_RS13105	COG3583	domain protein
SA_RS13115	COG1846	Transcriptional regulator
SA_RS13155	COG1070	Carbohydrate kinase
SA_RS13160	COG1802	Transcriptional regulator
SA_RS13165	COG0789	Transcriptional regulator
SA_RS13170	COG2357	RelA SpoT domain protein
SA_RS13175	COG4876	unkown
SA_RS13185	COG2271	Major facilitator Superfamily
SA_RS13190	COG0586	Pfam SNARE associated Golgi protein
SA_RS13200	COG1131	(ABC) transporter
SA_RS13220	COG3949	Membrane
SA_RS13225	COG0400	carboxylic ester hydrolase activity
SA_RS13230	COG0346	lactoylglutathione lyase activity
SA_RS13235	COG1846	Transcriptional regulator
SA_RS13245	COG2514	catechol 2,3-dioxygenase activity
SA_RS13260	COG0561	phosphatase activity
SA_RS13265	COG1131	(ABC) transporter
SA_RS13275	COG3764	Sortase (surface protein transpeptidase)
SA_RS13295	COG1760	l-serine dehydratase
SA_RS13300	COG1760	l-serine dehydratase
SA_RS13315	COG0697	spore germination
SA_RS13320	COG0657	acetylesterase activity
SA_RS13340	COG0028	Belongs to the TPP enzyme family
SA_RS13355	COG0583	DNA-binding transcription factor activity
SA_RS13365	COG3942	CHAP domain
SA_RS13375	COG3425	synthase
SA_RS13380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SA_RS13405	COG2409	Drug exporters of the RND superfamily
SA_RS13450	COG0436	Aminotransferase
SA_RS13480	COG3942	CHAP domain
SA_RS13485	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SA_RS13485	COG2755	lipolytic protein G-D-S-L family
SA_RS13595	COG3001	Fructosamine kinase
SA_RS13600	COG0167	dihydroorotate dehydrogenase activity
SA_RS13645	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
SA_RS13695	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SA_RS13700	COG3527	Alpha-acetolactate decarboxylase
SA_RS13715	COG0531	amino acid
SA_RS13745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA_RS13765	COG1012	belongs to the aldehyde dehydrogenase family
SA_RS13775	COG1510	regulation of RNA biosynthetic process
SA_RS13780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SA_RS13805	COG2851	Citrate transporter
SA_RS13820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SA_RS13830	COG0386	Belongs to the glutathione peroxidase family
SA_RS13855	COG1136	(ABC) transporter
SA_RS13860	COG2205	protein histidine kinase activity
SA_RS13865	COG0745	RESPONSE REGULATOR receiver
SA_RS13880	COG1785	Belongs to the alkaline phosphatase family
SA_RS13885	COG1846	Transcriptional regulator
SA_RS13930	COG1438	arginine binding
SA_RS13950	COG3711	transcriptional antiterminator
SA_RS13950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA_RS13955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA_RS13955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA_RS13955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA_RS13960	COG1482	cell wall glycoprotein biosynthetic process
SA_RS13970	COG3942	CHAP domain
SA_RS13970	COG1705	Flagellar rod assembly protein muramidase FlgJ
SA_RS13975	COG1535	isochorismatase
SA_RS13975	COG3433	isochorismatase activity
SA_RS13990	COG0438	transferase activity, transferring glycosyl groups
SA_RS14005	COG1073	alpha beta
SA_RS14025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SA_RS14045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SA_RS14135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SA_RS14220	COG0471	metal ion transport
SA_RS14225	COG2962	Rard protein
SA_RS14235	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SA_RS14250	COG1136	(ABC) transporter
SA_RS14255	COG0577	efflux transmembrane transporter activity
SA_RS14265	COG1278	Cold shock
SA_RS14285	COG1475	DNA binding