locus-tag	class	description
SA268_RS00020	COG2501	S4 domain
SA268_RS00040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SA268_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SA268_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SA268_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
SA268_RS00115	COG4863	YycH protein
SA268_RS00125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SA268_RS00130	COG0737	Belongs to the 5'-nucleotidase family
SA268_RS00155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA268_RS00155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA268_RS00200	COG0584	glycerophosphoryl diester phosphodiesterase
SA268_RS00205	COG2030	dehydratase
SA268_RS00315	COG1522	sequence-specific DNA binding
SA268_RS00320	COG0456	acetyltransferase
SA268_RS00345	COG0655	NAD(P)H dehydrogenase (quinone) activity
SA268_RS00380	COG0823	Involved in the tonB-independent uptake of proteins
SA268_RS00395	COG1473	amidohydrolase
SA268_RS00405	COG1283	sodium-dependent phosphate transmembrane transporter activity
SA268_RS00410	COG4716	Myosin-crossreactive antigen
SA268_RS00415	COG0697	spore germination
SA268_RS00430	COG1620	l-lactate permease
SA268_RS00450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA268_RS00455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA268_RS00460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SA268_RS00470	COG2423	ornithine cyclodeaminase activity
SA268_RS00475	COG4264	IucA IucC family
SA268_RS00480	COG2814	Major facilitator Superfamily
SA268_RS00485	COG4264	IucA IucC family
SA268_RS00490	COG4264	IucA IucC family
SA268_RS00500	COG0019	diaminopimelate decarboxylase activity
SA268_RS00505	COG1475	DNA binding
SA268_RS00535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SA268_RS00540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SA268_RS00545	COG0438	transferase activity, transferring glycosyl groups
SA268_RS00580	COG0813	purine-nucleoside phosphorylase activity
SA268_RS00585	COG2814	Major facilitator Superfamily
SA268_RS00605	COG3639	organic phosphonate transmembrane transporter activity
SA268_RS00625	COG0737	Belongs to the 5'-nucleotidase family
SA268_RS00640	COG1454	alcohol dehydrogenase
SA268_RS00640	COG1012	belongs to the aldehyde dehydrogenase family
SA268_RS00665	COG1086	Polysaccharide biosynthesis protein
SA268_RS00675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SA268_RS00705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SA268_RS00715	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SA268_RS00720	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SA268_RS00730	COG2832	Protein of unknown function (DUF454)
SA268_RS00765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SA268_RS00770	COG1960	acyl-CoA dehydrogenase activity
SA268_RS00790	COG3477	response to acidic pH
SA268_RS00815	COG1114	Component of the transport system for branched-chain amino acids
SA268_RS00820	COG1335	isochorismatase
SA268_RS00825	COG3961	Belongs to the TPP enzyme family
SA268_RS00850	COG1737	Transcriptional regulator
SA268_RS00875	COG0601	transmembrane transport
SA268_RS00880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA268_RS00890	COG0405	Gamma-glutamyltransferase
SA268_RS00910	COG3842	ATPase activity
SA268_RS00920	COG1175	transmembrane transport
SA268_RS00925	COG3833	ABC-type maltose transport systems, permease component
SA268_RS00930	COG0673	inositol 2-dehydrogenase activity
SA268_RS00935	COG0673	inositol 2-dehydrogenase activity
SA268_RS00945	COG1755	Isoprenylcysteine carboxyl methyltransferase
SA268_RS01005	COG0183	Belongs to the thiolase family
SA268_RS01015	COG1960	acyl-CoA dehydrogenase activity
SA268_RS01020	COG0318	PFAM AMP-dependent synthetase and ligase
SA268_RS01035	COG0747	negative chemotaxis
SA268_RS01040	COG3189	MarR family transcriptional regulator
SA268_RS01070	COG1263	PTS System
SA268_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA268_RS01070	COG2190	(PTS) system
SA268_RS01075	COG1957	nucleoside hydrolase
SA268_RS01095	COG3414	Phosphotransferase system galactitol-specific IIB component
SA268_RS01100	COG3775	system Galactitol-specific IIC component
SA268_RS01105	COG1063	alcohol dehydrogenase
SA268_RS01115	COG1063	alcohol dehydrogenase
SA268_RS01125	COG1063	alcohol dehydrogenase
SA268_RS01130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA268_RS01135	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA268_RS01145	COG1063	alcohol dehydrogenase
SA268_RS01150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA268_RS01185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SA268_RS01190	COG2190	(PTS) system
SA268_RS01190	COG1263	PTS System
SA268_RS01190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA268_RS01195	COG2723	6-phospho-beta-galactosidase activity
SA268_RS01200	COG2226	methyltransferase
SA268_RS01255	COG1131	(ABC) transporter
SA268_RS01275	COG3942	CHAP domain
SA268_RS01275	COG1388	LysM domain
SA268_RS01400	COG1114	Component of the transport system for branched-chain amino acids
SA268_RS01405	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SA268_RS01415	COG0577	efflux transmembrane transporter activity
SA268_RS01440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SA268_RS01445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SA268_RS01470	COG3314	Sporulation integral membrane protein YlbJ
SA268_RS01495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SA268_RS01520	COG3037	sugar-specific permease SgaT UlaA
SA268_RS01530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA268_RS01535	COG3711	transcriptional antiterminator
SA268_RS01555	COG2271	Major facilitator Superfamily
SA268_RS01560	COG0346	lactoylglutathione lyase activity
SA268_RS01570	COG0431	NADPH-dependent FMN reductase
SA268_RS01585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SA268_RS01590	COG2822	iron ion transport
SA268_RS01600	COG0672	)-iron permease
SA268_RS01605	COG0805	protein transport
SA268_RS01610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SA268_RS01620	COG1476	TRANSCRIPTIONal
SA268_RS01630	COG1131	(ABC) transporter
SA268_RS01665	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SA268_RS01665	COG0646	methionine synthase
SA268_RS01670	COG0626	cystathionine gamma-synthase activity
SA268_RS01675	COG0626	cystathionine gamma-synthase activity
SA268_RS01680	COG1475	DNA binding
SA268_RS01685	COG0668	transmembrane transport
SA268_RS01690	COG4481	Protein conserved in bacteria
SA268_RS01695	COG0012	GTP binding
SA268_RS01735	COG0582	viral genome integration into host DNA
SA268_RS01805	COG1823	symporter activity
SA268_RS01835	COG2233	PERMEase
SA268_RS01895	COG1683	Conserved Protein
SA268_RS01905	COG3759	membrane
SA268_RS02060	COG0523	cobalamin synthesis protein
SA268_RS02070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SA268_RS02080	COG5609	conserved protein (DUF2294)
SA268_RS02095	COG1647	Serine aminopeptidase, S33
SA268_RS02100	COG0733	neurotransmitter:sodium symporter activity
SA268_RS02105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SA268_RS02110	COG0626	cystathionine gamma-synthase activity
SA268_RS02120	COG2011	ABC-type metal ion transport system permease component
SA268_RS02125	COG1464	Belongs to the NlpA lipoprotein family
SA268_RS02140	COG0494	nUDIX hydrolase
SA268_RS02160	COG0583	DNA-binding transcription factor activity
SA268_RS02165	COG0069	glutamate synthase activity
SA268_RS02165	COG0067	glutamate synthase
SA268_RS02165	COG0070	glutamate synthase
SA268_RS02170	COG0493	'glutamate synthase
SA268_RS02180	COG1263	PTS System
SA268_RS02180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA268_RS02185	COG0366	Alpha amylase catalytic
SA268_RS02190	COG2188	Transcriptional regulator
SA268_RS02200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SA268_RS02240	COG1982	Orn Lys Arg decarboxylase major
SA268_RS02250	COG3870	Protein conserved in bacteria
SA268_RS02260	COG0470	DNA polymerase III
SA268_RS02265	COG1774	PSP1 C-terminal conserved region
SA268_RS02275	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SA268_RS02285	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SA268_RS02300	COG0084	hydrolase, TatD family'
SA268_RS02305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SA268_RS02315	COG4466	Protein conserved in bacteria
SA268_RS02325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SA268_RS02330	COG0251	oxidation-reduction process
SA268_RS02375	COG2244	polysaccharide biosynthetic process
SA268_RS02380	COG3956	TIGRFAM MazG family protein
SA268_RS02385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SA268_RS02395	COG1098	S1 RNA binding domain
SA268_RS02410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SA268_RS02435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SA268_RS02510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SA268_RS02525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SA268_RS02535	COG3880	PFAM UvrB UvrC protein
SA268_RS02555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SA268_RS02560	COG4956	integral membrane protein (PIN domain superfamily)
SA268_RS02580	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SA268_RS02630	COG2813	Specifically methylates the guanine in position
SA268_RS02670	COG1473	amidohydrolase
SA268_RS02700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SA268_RS02705	COG1428	Deoxynucleoside kinase
SA268_RS02710	COG1428	Deoxynucleoside kinase
SA268_RS02720	COG0561	phosphatase activity
SA268_RS02765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SA268_RS02875	COG0095	Lipoate-protein ligase
SA268_RS02880	COG0083	homoserine kinase activity
SA268_RS02900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SA268_RS02950	COG0667	Aldo Keto reductase
SA268_RS02955	COG0655	NAD(P)H dehydrogenase (quinone) activity
SA268_RS02965	COG1078	dGTPase activity
SA268_RS03000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SA268_RS03005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA268_RS03055	COG4974	Belongs to the 'phage' integrase family
SA268_RS03100	COG0803	Belongs to the bacterial solute-binding protein 9 family
SA268_RS03105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SA268_RS03110	COG1121	(ABC) transporter
SA268_RS03115	COG1321	iron dependent repressor
SA268_RS03125	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SA268_RS03135	COG1682	transport, permease protein
SA268_RS03140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA268_RS03150	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SA268_RS03155	COG1686	Belongs to the peptidase S11 family
SA268_RS03160	COG1132	(ABC) transporter
SA268_RS03165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SA268_RS03175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SA268_RS03180	COG1120	ATPase activity
SA268_RS03185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA268_RS03190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA268_RS03195	COG2376	Dihydroxyacetone kinase
SA268_RS03205	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SA268_RS03215	COG3949	Membrane
SA268_RS03240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SA268_RS03255	COG1136	(ABC) transporter
SA268_RS03260	COG0577	efflux transmembrane transporter activity
SA268_RS03265	COG1392	Phosphate transport regulator
SA268_RS03270	COG0306	phosphate transporter
SA268_RS03275	COG1388	LysM domain
SA268_RS03275	COG3942	CHAP domain
SA268_RS03285	COG4977	sequence-specific DNA binding
SA268_RS03285	COG1917	Cupin 2, conserved barrel domain protein
SA268_RS03315	COG0583	DNA-binding transcription factor activity
SA268_RS03330	COG2839	Protein conserved in bacteria
SA268_RS03360	COG1611	Belongs to the LOG family
SA268_RS03380	COG4988	ABC transporter
SA268_RS03385	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SA268_RS03395	COG0523	cobalamin synthesis protein
SA268_RS03400	COG4989	oxidoreductase activity
SA268_RS03410	COG0471	metal ion transport
SA268_RS03415	COG0415	Belongs to the DNA photolyase family
SA268_RS03445	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SA268_RS03450	COG1349	DNA-binding transcription factor activity
SA268_RS03455	COG1105	Belongs to the carbohydrate kinase PfkB family
SA268_RS03460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA268_RS03460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA268_RS03460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA268_RS03470	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SA268_RS03475	COG1253	flavin adenine dinucleotide binding
SA268_RS03480	COG0656	L-ascorbic acid biosynthetic process
SA268_RS03485	COG0463	Glycosyl transferase, family 2
SA268_RS03520	COG0720	synthase
SA268_RS03530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SA268_RS03530	COG0512	Glutamine amidotransferase of anthranilate synthase
SA268_RS03535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SA268_RS03570	COG0488	(ABC) transporter
SA268_RS03575	COG0514	ATP-dependent DNA helicase (RecQ)
SA268_RS03580	COG0517	IMP dehydrogenase activity
SA268_RS03580	COG1125	glycine betaine transport
SA268_RS03585	COG1174	glycine betaine transport
SA268_RS03610	COG3104	oligopeptide transport
SA268_RS03630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SA268_RS03635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SA268_RS03645	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA268_RS03650	COG4605	iron ion homeostasis
SA268_RS03655	COG4604	ABC transporter, ATP-binding protein
SA268_RS03660	COG4607	ABC-type enterochelin transport system periplasmic component
SA268_RS03705	COG2966	Psort location CytoplasmicMembrane, score
SA268_RS03715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SA268_RS03720	COG1739	Uncharacterized protein family UPF0029
SA268_RS03730	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SA268_RS03735	COG1040	competence protein
SA268_RS03765	COG3942	CHAP domain
SA268_RS03765	COG1388	LysM domain
SA268_RS03820	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SA268_RS03840	COG0281	malic enzyme
SA268_RS03895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SA268_RS03900	COG1647	Serine aminopeptidase, S33
SA268_RS03905	COG0557	exoribonuclease II activity
SA268_RS03965	COG1278	Cold shock
SA268_RS04005	COG0406	alpha-ribazole phosphatase activity
SA268_RS04010	COG1279	arginine transmembrane transporter activity
SA268_RS04035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SA268_RS04040	COG1393	Belongs to the ArsC family
SA268_RS04055	COG3878	Protein conserved in bacteria
SA268_RS04065	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SA268_RS04080	COG2011	ABC-type metal ion transport system permease component
SA268_RS04085	COG1464	Belongs to the NlpA lipoprotein family
SA268_RS04090	COG0582	viral genome integration into host DNA
SA268_RS04195	COG3728	DNA packaging
SA268_RS04195	COG5484	DNA packaging
SA268_RS04235	COG0396	ATPase activity
SA268_RS04240	COG0719	Fe-S assembly protein
SA268_RS04250	COG0822	iron-sulfur transferase activity
SA268_RS04270	COG1253	flavin adenine dinucleotide binding
SA268_RS04285	COG1801	Protein of unknown function DUF72
SA268_RS04290	COG0730	response to heat
SA268_RS04305	COG4470	Protein conserved in bacteria
SA268_RS04315	COG2445	Protein of unknown function DUF86
SA268_RS04345	COG1696	Membrane protein involved in D-alanine export
SA268_RS04355	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SA268_RS04360	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SA268_RS04365	COG4837	Protein of unknown function (DUF1462)
SA268_RS04370	COG1252	NADH dehydrogenase
SA268_RS04380	COG0316	Belongs to the HesB IscA family
SA268_RS04390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SA268_RS04395	COG2056	Na+-H+ antiporter family
SA268_RS04400	COG2050	protein possibly involved in aromatic compounds catabolism
SA268_RS04455	COG1098	S1 RNA binding domain
SA268_RS04460	COG1902	pentaerythritol trinitrate reductase activity
SA268_RS04475	COG0584	glycerophosphoryl diester phosphodiesterase
SA268_RS04495	COG0398	Pfam SNARE associated Golgi protein
SA268_RS04535	COG0561	phosphatase activity
SA268_RS04580	COG1881	PFAM PEBP family protein
SA268_RS04610	COG0601	transmembrane transport
SA268_RS04615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA268_RS04620	COG0444	Belongs to the ABC transporter superfamily
SA268_RS04625	COG4608	Belongs to the ABC transporter superfamily
SA268_RS04630	COG4166	transmembrane transport
SA268_RS04635	COG0747	negative chemotaxis
SA268_RS04640	COG0444	Belongs to the ABC transporter superfamily
SA268_RS04645	COG4608	Belongs to the ABC transporter superfamily
SA268_RS04650	COG0601	transmembrane transport
SA268_RS04655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA268_RS04685	COG1164	Oligoendopeptidase f
SA268_RS04695	COG2346	COG2346, Truncated hemoglobins
SA268_RS04710	COG2357	RelA SpoT domain protein
SA268_RS04720	COG0564	pseudouridine synthase activity
SA268_RS04725	COG2239	Acts as a magnesium transporter
SA268_RS04730	COG0475	glutathione-regulated potassium exporter activity
SA268_RS04730	COG0569	domain protein
SA268_RS04740	COG0628	permease
SA268_RS04745	COG1115	amino acid carrier protein
SA268_RS04795	COG0861	Integral membrane protein TerC family
SA268_RS04805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SA268_RS04810	COG0737	Belongs to the 5'-nucleotidase family
SA268_RS04825	COG4903	ComK protein
SA268_RS04840	COG4873	Protein conserved in bacteria
SA268_RS04895	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SA268_RS04905	COG2314	TM2 domain
SA268_RS04910	COG0456	acetyltransferase
SA268_RS04915	COG1575	Belongs to the MenA family. Type 1 subfamily
SA268_RS04920	COG1169	isochorismate synthase
SA268_RS04930	COG2267	carboxylic ester hydrolase activity
SA268_RS04955	COG0436	Aminotransferase
SA268_RS04990	COG1316	TRANSCRIPTIONal
SA268_RS05035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SA268_RS05050	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SA268_RS05090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SA268_RS05095	COG4172	Belongs to the ABC transporter superfamily
SA268_RS05100	COG4721	ABC-type cobalt transport system, permease component
SA268_RS05120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SA268_RS05140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SA268_RS05145	COG1271	oxidase subunit
SA268_RS05150	COG1294	oxidase, subunit
SA268_RS05155	COG0569	domain protein
SA268_RS05220	COG1176	ABC-type spermidine putrescine transport system, permease component I
SA268_RS05225	COG1177	transmembrane transport
SA268_RS05230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SA268_RS05255	COG0483	inositol monophosphate 1-phosphatase activity
SA268_RS05265	COG1217	gtp-binding protein TYPA
SA268_RS05275	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SA268_RS05285	COG0772	Belongs to the SEDS family
SA268_RS05320	COG3679	Belongs to the UPF0342 family
SA268_RS05340	COG0742	ribosomal rna small subunit methyltransferase
SA268_RS05400	COG4509	Sortase family
SA268_RS05415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SA268_RS05445	COG1796	DNA polymerase
SA268_RS05445	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SA268_RS05470	COG2009	succinate dehydrogenase
SA268_RS05475	COG1053	succinate dehydrogenase
SA268_RS05480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SA268_RS05600	COG1288	antiporter activity
SA268_RS05635	COG1011	Hydrolase
SA268_RS05660	COG4839	cell division protein FtsL
SA268_RS05665	COG0768	penicillin binding
SA268_RS05680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SA268_RS05685	COG0849	cell division
SA268_RS05700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SA268_RS05710	COG0762	integral membrane protein
SA268_RS05715	COG2302	S4 RNA-binding domain
SA268_RS05720	COG3599	regulation of cell shape
SA268_RS05730	COG2514	catechol 2,3-dioxygenase activity
SA268_RS05750	COG0564	pseudouridine synthase activity
SA268_RS05760	COG2233	PERMEase
SA268_RS05805	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SA268_RS05820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SA268_RS05825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SA268_RS05835	COG2314	TM2 domain
SA268_RS05850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SA268_RS05850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SA268_RS05860	COG0631	protein serine/threonine phosphatase activity
SA268_RS05875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SA268_RS05890	COG1302	Protein conserved in bacteria
SA268_RS05940	COG1196	nuclear chromosome segregation
SA268_RS05945	COG0552	protein localization to endoplasmic reticulum
SA268_RS05955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SA268_RS06015	COG2348	transferase activity, transferring amino-acyl groups
SA268_RS06020	COG0758	DNA mediated transformation
SA268_RS06115	COG0195	Participates in both transcription termination and antitermination
SA268_RS06120	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SA268_RS06145	COG0196	riboflavin kinase activity
SA268_RS06170	COG2188	Transcriptional regulator
SA268_RS06175	COG0612	Peptidase, M16
SA268_RS06185	COG0300	oxidoreductase activity
SA268_RS06210	COG1058	Belongs to the CinA family
SA268_RS06210	COG1546	Belongs to the CinA family
SA268_RS06230	COG1692	metallophosphoesterase
SA268_RS06235	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SA268_RS06235	COG0674	pyruvate-flavodoxin oxidoreductase activity
SA268_RS06240	COG1013	pyruvate-flavodoxin oxidoreductase activity
SA268_RS06275	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SA268_RS06280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SA268_RS06305	COG1923	regulation of RNA biosynthetic process
SA268_RS06315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SA268_RS06320	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SA268_RS06325	COG0789	Transcriptional regulator
SA268_RS06455	COG1525	nuclease
SA268_RS06470	COG0527	aspartate kinase activity
SA268_RS06475	COG0460	homoserine dehydrogenase
SA268_RS06480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SA268_RS06505	COG0833	amino acid
SA268_RS06535	COG2340	Cysteine-rich secretory protein family
SA268_RS06570	COG4846	Membrane protein involved in cytochrome C biogenesis
SA268_RS06590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SA268_RS06600	COG0824	Thioesterase
SA268_RS06620	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SA268_RS06630	COG1115	amino acid carrier protein
SA268_RS06645	COG0628	permease
SA268_RS06670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SA268_RS06680	COG1363	Peptidase, m42
SA268_RS06685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SA268_RS06690	COG0512	Glutamine amidotransferase of anthranilate synthase
SA268_RS06730	COG0561	phosphatase activity
SA268_RS06775	COG0704	Plays a role in the regulation of phosphate uptake
SA268_RS06785	COG0581	inorganic phosphate transmembrane transporter activity
SA268_RS06790	COG0573	inorganic phosphate transmembrane transporter activity
SA268_RS06805	COG0488	(ABC) transporter
SA268_RS06810	COG0527	aspartate kinase activity
SA268_RS06815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SA268_RS06850	COG2808	Putative FMN-binding domain
SA268_RS06895	COG4548	von Willebrand factor, type A
SA268_RS06900	COG0714	Associated with various cellular activities
SA268_RS06935	COG0671	phosphoesterase, PA-phosphatase related
SA268_RS07015	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SA268_RS07040	COG0531	amino acid
SA268_RS07055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA268_RS07060	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SA268_RS07075	COG0116	Belongs to the methyltransferase superfamily
SA268_RS07105	COG4499	WXG100 protein secretion system (Wss), protein YukC
SA268_RS07105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SA268_RS07115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SA268_RS07120	COG3935	DnaD domain protein
SA268_RS07145	COG0438	transferase activity, transferring glycosyl groups
SA268_RS07150	COG1694	Mazg nucleotide pyrophosphohydrolase
SA268_RS07155	COG2738	Putative neutral zinc metallopeptidase
SA268_RS07160	COG4347	Protein of unknown function (DUF1405)
SA268_RS07200	COG0142	geranyltranstransferase activity
SA268_RS07265	COG0492	ferredoxin-NADP+ reductase activity
SA268_RS07280	COG0514	ATP-dependent DNA helicase (RecQ)
SA268_RS07290	COG1141	Ferredoxin
SA268_RS07325	COG0860	N-Acetylmuramoyl-L-alanine amidase
SA268_RS07325	COG1388	LysM domain
SA268_RS07360	COG0739	heme binding
SA268_RS07410	COG0740	serine-type endopeptidase activity
SA268_RS07510	COG1484	DNA-dependent DNA replication
SA268_RS07530	COG0629	single-stranded DNA binding
SA268_RS07640	COG0582	viral genome integration into host DNA
SA268_RS07660	COG5002	protein histidine kinase activity
SA268_RS07665	COG0745	RESPONSE REGULATOR receiver
SA268_RS07670	COG1187	pseudouridine synthase activity
SA268_RS07695	COG0735	belongs to the Fur family
SA268_RS07700	COG0494	nUDIX hydrolase
SA268_RS07705	COG0667	Aldo Keto reductase
SA268_RS07715	COG4221	oxidoreductase activity
SA268_RS07730	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SA268_RS07740	COG0366	Alpha amylase catalytic
SA268_RS07745	COG1609	Transcriptional regulator
SA268_RS07765	COG2195	Cleaves the N-terminal amino acid of tripeptides
SA268_RS07775	COG4129	membrane
SA268_RS07785	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA268_RS07790	COG0022	dehydrogenase e1 component
SA268_RS07795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SA268_RS07800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SA268_RS07805	COG0497	DNA recombination
SA268_RS07835	COG1302	Protein conserved in bacteria
SA268_RS07840	COG0439	Biotin carboxylase
SA268_RS07845	COG0511	ligase activity, forming carbon-carbon bonds
SA268_RS07855	COG0006	proline dipeptidase activity
SA268_RS07870	COG0095	Lipoate-protein ligase
SA268_RS07875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SA268_RS07920	COG4537	Required for transformation and DNA binding
SA268_RS07925	COG1459	type II secretion system
SA268_RS07930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SA268_RS07935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA268_RS07940	COG0011	TIGRFAM Protein of
SA268_RS07945	COG1940	carbohydrate kinase activity
SA268_RS07950	COG4483	Protein conserved in bacteria
SA268_RS07960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SA268_RS07970	COG0768	penicillin binding
SA268_RS07985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SA268_RS07990	COG1121	(ABC) transporter
SA268_RS08000	COG0513	Belongs to the DEAD box helicase family
SA268_RS08010	COG2384	SAM-dependent methyltransferase
SA268_RS08030	COG0517	IMP dehydrogenase activity
SA268_RS08050	COG0295	cytidine deaminase activity
SA268_RS08055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SA268_RS08065	COG1702	phosphate starvation-inducible protein PhoH
SA268_RS08080	COG1030	water channel activity
SA268_RS08090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SA268_RS08095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SA268_RS08125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SA268_RS08140	COG1466	dna polymerase III delta subunit
SA268_RS08145	COG2333	competence protein COMEC
SA268_RS08145	COG0658	competence protein
SA268_RS08150	COG2131	deaminase
SA268_RS08160	COG2226	methyltransferase
SA268_RS08165	COG0799	negative regulation of ribosome biogenesis
SA268_RS08170	COG1713	HD superfamily hydrolase involved in NAD metabolism
SA268_RS08180	COG1534	Rna-binding protein
SA268_RS08190	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SA268_RS08195	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SA268_RS08225	COG3177	Filamentation induced by cAMP protein fic
SA268_RS08230	COG1914	H( )-stimulated, divalent metal cation uptake system
SA268_RS08240	COG0439	Biotin carboxylase
SA268_RS08245	COG0511	ligase activity, forming carbon-carbon bonds
SA268_RS08250	COG1984	allophanate hydrolase subunit 2
SA268_RS08255	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SA268_RS08270	COG0826	peptidase U32
SA268_RS08275	COG0826	peptidase U32
SA268_RS08305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SA268_RS08320	COG1104	cysteine desulfurase activity
SA268_RS08325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SA268_RS08335	COG3237	CsbD-like
SA268_RS08340	COG1959	2 iron, 2 sulfur cluster binding
SA268_RS08345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SA268_RS08350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SA268_RS08390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SA268_RS08390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SA268_RS08395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SA268_RS08395	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SA268_RS08400	COG1862	Preprotein translocase
SA268_RS08440	COG2868	ribosomal protein
SA268_RS08480	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SA268_RS08490	COG0285	dihydrofolate synthase activity
SA268_RS08500	COG2818	Glycosylase
SA268_RS08535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SA268_RS08570	COG4112	unkown
SA268_RS08595	COG0833	amino acid
SA268_RS08610	COG1484	DNA-dependent DNA replication
SA268_RS08640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA268_RS08640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA268_RS08650	COG5002	protein histidine kinase activity
SA268_RS08655	COG0745	RESPONSE REGULATOR receiver
SA268_RS08670	COG0372	Belongs to the citrate synthase family
SA268_RS08675	COG1113	amino acid transport
SA268_RS08700	COG0281	malic enzyme
SA268_RS08710	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SA268_RS08715	COG4109	DRTGG domain
SA268_RS08755	COG0827	DNA restriction-modification system
SA268_RS08765	COG0730	response to heat
SA268_RS08775	COG1104	cysteine desulfurase activity
SA268_RS08785	COG1956	GAF domain-containing protein
SA268_RS08800	COG0584	glycerophosphoryl diester phosphodiesterase
SA268_RS08805	COG1764	response to oxidative stress
SA268_RS08810	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SA268_RS08815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SA268_RS08840	COG1263	PTS System
SA268_RS08840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA268_RS08845	COG0204	Acyl-transferase
SA268_RS08850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SA268_RS08885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA268_RS08890	COG0454	-acetyltransferase
SA268_RS08910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SA268_RS08910	COG1605	Chorismate mutase
SA268_RS08935	COG1674	ftsk spoiiie
SA268_RS08940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SA268_RS08950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SA268_RS08955	COG1363	Peptidase, m42
SA268_RS08965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA268_RS08975	COG0510	thiamine kinase activity
SA268_RS08995	COG1187	pseudouridine synthase activity
SA268_RS09000	COG2244	polysaccharide biosynthetic process
SA268_RS09005	COG2081	HI0933 family
SA268_RS09025	COG2814	Major facilitator Superfamily
SA268_RS09030	COG1242	4 iron, 4 sulfur cluster binding
SA268_RS09035	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SA268_RS09045	COG2267	carboxylic ester hydrolase activity
SA268_RS09075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SA268_RS09075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SA268_RS09100	COG3266	domain, Protein
SA268_RS09100	COG5632	N-Acetylmuramoyl-L-alanine amidase
SA268_RS09100	COG4193	domain, Protein
SA268_RS09135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SA268_RS09155	COG0656	L-ascorbic acid biosynthetic process
SA268_RS09175	COG1506	peptidase
SA268_RS09180	COG2816	NAD+ diphosphatase activity
SA268_RS09280	COG0860	N-Acetylmuramoyl-L-alanine amidase
SA268_RS09280	COG1388	LysM domain
SA268_RS09315	COG5632	N-Acetylmuramoyl-L-alanine amidase
SA268_RS09315	COG1388	LysM domain
SA268_RS09530	COG1484	DNA-dependent DNA replication
SA268_RS09550	COG0629	single-stranded DNA binding
SA268_RS09680	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SA268_RS09710	COG1131	(ABC) transporter
SA268_RS09715	COG0537	adenosine 5'-monophosphoramidase activity
SA268_RS09745	COG0420	3'-5' exonuclease activity
SA268_RS09770	COG2197	response regulator
SA268_RS09775	COG4585	Histidine kinase
SA268_RS09775	COG2203	Gaf domain
SA268_RS09780	COG0564	pseudouridine synthase activity
SA268_RS09820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SA268_RS09825	COG1126	abc transporter atp-binding protein
SA268_RS09830	COG0765	amino acid transport
SA268_RS09995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SA268_RS10000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SA268_RS10010	COG4129	membrane
SA268_RS10030	COG1194	a g-specific adenine glycosylase
SA268_RS10035	COG1988	membrane-bound metal-dependent
SA268_RS10050	COG1388	LysM domain
SA268_RS10050	COG1134	teichoic acid transport
SA268_RS10080	COG0535	radical SAM domain protein
SA268_RS10085	COG1607	acyl-coa hydrolase
SA268_RS10090	COG2309	aminopeptidase activity
SA268_RS10110	COG1295	ribonuclease BN
SA268_RS10225	COG4851	CamS sex pheromone cAM373 precursor
SA268_RS10245	COG4496	protein, YerC YecD
SA268_RS10280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SA268_RS10290	COG0077	Prephenate dehydratase
SA268_RS10300	COG0471	metal ion transport
SA268_RS10310	COG1335	isochorismatase
SA268_RS10325	COG1012	belongs to the aldehyde dehydrogenase family
SA268_RS10375	COG1131	(ABC) transporter
SA268_RS10390	COG1725	Transcriptional regulator
SA268_RS10445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SA268_RS10510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SA268_RS10515	COG1621	beta-fructofuranosidase activity
SA268_RS10520	COG1609	Transcriptional regulator
SA268_RS10525	COG0004	ammonium transporteR
SA268_RS10530	COG0425	Belongs to the sulfur carrier protein TusA family
SA268_RS10535	COG2391	methyltransferase activity
SA268_RS10545	COG0488	(ABC) transporter
SA268_RS10560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SA268_RS10570	COG0456	acetyltransferase
SA268_RS10575	COG1214	PFAM Peptidase M22, glycoprotease
SA268_RS10580	COG0802	atpase or kinase
SA268_RS10595	COG0028	Belongs to the TPP enzyme family
SA268_RS10670	COG2183	response to ionizing radiation
SA268_RS10675	COG1191	sigma factor activity
SA268_RS10685	COG1366	Belongs to the anti-sigma-factor antagonist family
SA268_RS10690	COG2208	phosphoserine phosphatase activity
SA268_RS10725	COG3428	Bacterial PH domain
SA268_RS10755	COG2205	protein histidine kinase activity
SA268_RS10760	COG0745	RESPONSE REGULATOR receiver
SA268_RS10770	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SA268_RS10780	COG0772	Belongs to the SEDS family
SA268_RS10795	COG1937	Protein conserved in bacteria
SA268_RS10805	COG1418	mRNA catabolic process
SA268_RS10850	COG0629	single-stranded DNA binding
SA268_RS10940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SA268_RS10965	COG0009	L-threonylcarbamoyladenylate synthase
SA268_RS10970	COG2890	protein-(glutamine-N5) methyltransferase activity
SA268_RS10990	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SA268_RS11030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SA268_RS11085	COG0813	purine-nucleoside phosphorylase activity
SA268_RS11090	COG0783	Belongs to the Dps family
SA268_RS11110	COG1482	cell wall glycoprotein biosynthetic process
SA268_RS11115	COG0702	epimerase
SA268_RS11120	COG0640	Transcriptional regulator
SA268_RS11160	COG0561	phosphatase activity
SA268_RS11165	COG1119	ATPase activity
SA268_RS11180	COG3711	transcriptional antiterminator
SA268_RS11210	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SA268_RS11270	COG0489	protein tyrosine kinase activity
SA268_RS11275	COG2814	Major facilitator Superfamily
SA268_RS11290	COG1272	protein, Hemolysin III
SA268_RS11300	COG1988	membrane-bound metal-dependent
SA268_RS11310	COG3314	Sporulation integral membrane protein YlbJ
SA268_RS11315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA268_RS11320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA268_RS11325	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SA268_RS11335	COG3457	Alanine racemase
SA268_RS11340	COG4264	IucA IucC family
SA268_RS11345	COG2814	Major facilitator Superfamily
SA268_RS11370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SA268_RS11380	COG2130	NADP-dependent
SA268_RS11445	COG0656	L-ascorbic acid biosynthetic process
SA268_RS11450	COG0789	Transcriptional regulator
SA268_RS11460	COG5492	domain, Protein
SA268_RS11465	COG2378	regulation of single-species biofilm formation
SA268_RS11470	COG0693	protein deglycase activity
SA268_RS11480	COG3527	Alpha-acetolactate decarboxylase
SA268_RS11485	COG0028	Belongs to the TPP enzyme family
SA268_RS11565	COG0201	protein transport
SA268_RS11680	COG2252	PERMEase
SA268_RS11725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SA268_RS11785	COG1763	Mo-molybdopterin cofactor biosynthetic process
SA268_RS11805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SA268_RS11810	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SA268_RS11815	COG4149	molybdate abc transporter
SA268_RS11820	COG0725	ABC transporter, periplasmic molybdate-binding protein
SA268_RS11835	COG1268	BioY protein
SA268_RS11850	COG1960	acyl-CoA dehydrogenase activity
SA268_RS11855	COG4413	Urea transporter
SA268_RS11930	COG1757	Na H antiporter
SA268_RS11945	COG3942	CHAP domain
SA268_RS11985	COG1316	TRANSCRIPTIONal
SA268_RS12015	COG1113	amino acid transport
SA268_RS12035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SA268_RS12040	COG0385	Bile acid
SA268_RS12055	COG1737	Transcriptional regulator
SA268_RS12075	COG1028	Short-chain dehydrogenase reductase Sdr
SA268_RS12080	COG1473	amidohydrolase
SA268_RS12095	COG0583	DNA-binding transcription factor activity
SA268_RS12115	COG2258	MOSC domain
SA268_RS12135	COG1668	transmembrane transport
SA268_RS12140	COG4152	abc transporter atp-binding protein
SA268_RS12145	COG3152	Membrane
SA268_RS12155	COG0786	glutamate:sodium symporter activity
SA268_RS12165	COG0598	Magnesium transport protein CorA
SA268_RS12180	COG0657	acetylesterase activity
SA268_RS12190	COG2814	Major facilitator Superfamily
SA268_RS12195	COG1566	PFAM secretion protein HlyD family protein
SA268_RS12215	COG2814	Major facilitator Superfamily
SA268_RS12280	COG1131	(ABC) transporter
SA268_RS12295	COG1620	l-lactate permease
SA268_RS12315	COG0604	alcohol dehydrogenase
SA268_RS12345	COG1511	domain protein
SA268_RS12360	COG1263	PTS System
SA268_RS12360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA268_RS12375	COG3871	stress protein (general stress protein 26)
SA268_RS12415	COG0789	Transcriptional regulator
SA268_RS12435	COG2181	nitrate reductase activity
SA268_RS12445	COG1140	nitrate reductase beta subunit
SA268_RS12450	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SA268_RS12460	COG2146	nitrite reductase [NAD(P)H] activity
SA268_RS12465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SA268_RS12475	COG0454	-acetyltransferase
SA268_RS12480	COG2116	formate transmembrane transporter activity
SA268_RS12495	COG0803	Belongs to the bacterial solute-binding protein 9 family
SA268_RS12495	COG3443	Belongs to the bacterial solute-binding protein 9 family
SA268_RS12530	COG1126	abc transporter atp-binding protein
SA268_RS12535	COG0765	amino acid transport
SA268_RS12540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SA268_RS12545	COG2814	Major facilitator Superfamily
SA268_RS12560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SA268_RS12605	COG0156	8-amino-7-oxononanoate synthase activity
SA268_RS12615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SA268_RS12620	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SA268_RS12635	COG1132	(ABC) transporter
SA268_RS12640	COG1132	(ABC) transporter
SA268_RS12640	COG2375	cellular response to nickel ion
SA268_RS12655	COG1929	Belongs to the glycerate kinase type-1 family
SA268_RS12665	COG2814	Major facilitator Superfamily
SA268_RS12680	COG1408	metallophosphoesterase
SA268_RS12685	COG1113	amino acid transport
SA268_RS12700	COG0531	amino acid
SA268_RS12725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SA268_RS12735	COG1174	glycine betaine transport
SA268_RS12745	COG1174	glycine betaine transport
SA268_RS12765	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SA268_RS12770	COG0531	amino acid
SA268_RS12775	COG2272	Belongs to the type-B carboxylesterase lipase family
SA268_RS12780	COG2814	Major facilitator Superfamily
SA268_RS12785	COG0390	transport system, permease component
SA268_RS12790	COG4619	ABC transporter
SA268_RS12795	COG1363	Peptidase, m42
SA268_RS12800	COG4808	Protein conserved in bacteria
SA268_RS12805	COG0069	glutamate synthase activity
SA268_RS12820	COG1124	(ABC) transporter
SA268_RS12830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA268_RS12835	COG0601	transmembrane transport
SA268_RS12840	COG0747	negative chemotaxis
SA268_RS12865	COG1028	Short-chain dehydrogenase reductase Sdr
SA268_RS12870	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SA268_RS12875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SA268_RS12975	COG0494	nUDIX hydrolase
SA268_RS13030	COG1846	Transcriptional regulator
SA268_RS13060	COG1070	Carbohydrate kinase
SA268_RS13065	COG1802	Transcriptional regulator
SA268_RS13070	COG0789	Transcriptional regulator
SA268_RS13075	COG2357	RelA SpoT domain protein
SA268_RS13080	COG4876	unkown
SA268_RS13090	COG2271	Major facilitator Superfamily
SA268_RS13095	COG0586	Pfam SNARE associated Golgi protein
SA268_RS13105	COG1131	(ABC) transporter
SA268_RS13115	COG1073	alpha beta
SA268_RS13125	COG1073	alpha beta
SA268_RS13150	COG3949	Membrane
SA268_RS13155	COG0400	carboxylic ester hydrolase activity
SA268_RS13160	COG0346	lactoylglutathione lyase activity
SA268_RS13165	COG1846	Transcriptional regulator
SA268_RS13180	COG2514	catechol 2,3-dioxygenase activity
SA268_RS13195	COG0561	phosphatase activity
SA268_RS13200	COG1131	(ABC) transporter
SA268_RS13210	COG3764	Sortase (surface protein transpeptidase)
SA268_RS13230	COG1760	l-serine dehydratase
SA268_RS13235	COG1760	l-serine dehydratase
SA268_RS13250	COG0697	spore germination
SA268_RS13255	COG0657	acetylesterase activity
SA268_RS13275	COG0028	Belongs to the TPP enzyme family
SA268_RS13290	COG0583	DNA-binding transcription factor activity
SA268_RS13300	COG3942	CHAP domain
SA268_RS13310	COG3425	synthase
SA268_RS13320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SA268_RS13345	COG2409	Drug exporters of the RND superfamily
SA268_RS13390	COG0436	Aminotransferase
SA268_RS13430	COG0456	acetyltransferase
SA268_RS13500	COG0596	Alpha beta hydrolase
SA268_RS13535	COG3001	Fructosamine kinase
SA268_RS13540	COG0167	dihydroorotate dehydrogenase activity
SA268_RS13625	COG2226	methyltransferase
SA268_RS13660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SA268_RS13660	COG0551	DNA topoisomerase type I activity
SA268_RS13665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SA268_RS13710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SA268_RS13715	COG3527	Alpha-acetolactate decarboxylase
SA268_RS13730	COG0531	amino acid
SA268_RS13760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA268_RS13780	COG1012	belongs to the aldehyde dehydrogenase family
SA268_RS13790	COG1510	regulation of RNA biosynthetic process
SA268_RS13795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SA268_RS13820	COG2851	Citrate transporter
SA268_RS13830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SA268_RS13840	COG0386	Belongs to the glutathione peroxidase family
SA268_RS13865	COG1136	(ABC) transporter
SA268_RS13870	COG2205	protein histidine kinase activity
SA268_RS13875	COG0745	RESPONSE REGULATOR receiver
SA268_RS13890	COG1785	Belongs to the alkaline phosphatase family
SA268_RS13895	COG1846	Transcriptional regulator
SA268_RS13940	COG1438	arginine binding
SA268_RS13960	COG3711	transcriptional antiterminator
SA268_RS13960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA268_RS13965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA268_RS13965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA268_RS13965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA268_RS13970	COG1482	cell wall glycoprotein biosynthetic process
SA268_RS13980	COG3942	CHAP domain
SA268_RS13980	COG1705	Flagellar rod assembly protein muramidase FlgJ
SA268_RS13985	COG1535	isochorismatase
SA268_RS13985	COG3433	isochorismatase activity
SA268_RS14000	COG0438	transferase activity, transferring glycosyl groups
SA268_RS14015	COG1073	alpha beta
SA268_RS14035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SA268_RS14065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SA268_RS14170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SA268_RS14255	COG0471	metal ion transport
SA268_RS14260	COG2962	Rard protein
SA268_RS14270	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SA268_RS14285	COG1136	(ABC) transporter
SA268_RS14290	COG0577	efflux transmembrane transporter activity
SA268_RS14315	COG1278	Cold shock
SA268_RS14335	COG1475	DNA binding