locus-tag	class	description
SA40_RS00020	COG2501	S4 domain
SA40_RS00040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SA40_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SA40_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SA40_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
SA40_RS00115	COG4863	YycH protein
SA40_RS00125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SA40_RS00130	COG0737	Belongs to the 5'-nucleotidase family
SA40_RS00160	COG0584	glycerophosphoryl diester phosphodiesterase
SA40_RS00165	COG2030	dehydratase
SA40_RS00230	COG2801	Transposase and inactivated derivatives
SA40_RS00270	COG1522	sequence-specific DNA binding
SA40_RS00275	COG0456	acetyltransferase
SA40_RS00300	COG0655	NAD(P)H dehydrogenase (quinone) activity
SA40_RS00335	COG0823	Involved in the tonB-independent uptake of proteins
SA40_RS00350	COG1473	amidohydrolase
SA40_RS00360	COG1283	sodium-dependent phosphate transmembrane transporter activity
SA40_RS00365	COG4716	Myosin-crossreactive antigen
SA40_RS00370	COG0697	spore germination
SA40_RS00385	COG1620	l-lactate permease
SA40_RS00405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA40_RS00410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA40_RS00415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SA40_RS00425	COG2423	ornithine cyclodeaminase activity
SA40_RS00430	COG4264	IucA IucC family
SA40_RS00435	COG2814	Major facilitator Superfamily
SA40_RS00440	COG4264	IucA IucC family
SA40_RS00445	COG4264	IucA IucC family
SA40_RS00455	COG0019	diaminopimelate decarboxylase activity
SA40_RS00460	COG1475	DNA binding
SA40_RS00490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SA40_RS00495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SA40_RS00500	COG0438	transferase activity, transferring glycosyl groups
SA40_RS00535	COG0813	purine-nucleoside phosphorylase activity
SA40_RS00540	COG2814	Major facilitator Superfamily
SA40_RS00560	COG3639	organic phosphonate transmembrane transporter activity
SA40_RS00580	COG0737	Belongs to the 5'-nucleotidase family
SA40_RS00595	COG1012	belongs to the aldehyde dehydrogenase family
SA40_RS00595	COG1454	alcohol dehydrogenase
SA40_RS00620	COG1086	Polysaccharide biosynthesis protein
SA40_RS00630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SA40_RS00660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SA40_RS00670	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SA40_RS00675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SA40_RS00685	COG2832	Protein of unknown function (DUF454)
SA40_RS00720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SA40_RS00725	COG1960	acyl-CoA dehydrogenase activity
SA40_RS00745	COG3477	response to acidic pH
SA40_RS00770	COG1114	Component of the transport system for branched-chain amino acids
SA40_RS00775	COG1335	isochorismatase
SA40_RS00780	COG3961	Belongs to the TPP enzyme family
SA40_RS00805	COG1737	Transcriptional regulator
SA40_RS00830	COG0601	transmembrane transport
SA40_RS00835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA40_RS00845	COG0405	Gamma-glutamyltransferase
SA40_RS00865	COG3842	ATPase activity
SA40_RS00875	COG1175	transmembrane transport
SA40_RS00880	COG3833	ABC-type maltose transport systems, permease component
SA40_RS00885	COG0673	inositol 2-dehydrogenase activity
SA40_RS00890	COG0673	inositol 2-dehydrogenase activity
SA40_RS00900	COG1755	Isoprenylcysteine carboxyl methyltransferase
SA40_RS00960	COG0183	Belongs to the thiolase family
SA40_RS00970	COG1960	acyl-CoA dehydrogenase activity
SA40_RS00975	COG0318	PFAM AMP-dependent synthetase and ligase
SA40_RS00990	COG0747	negative chemotaxis
SA40_RS00995	COG3189	MarR family transcriptional regulator
SA40_RS01025	COG1263	PTS System
SA40_RS01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA40_RS01025	COG2190	(PTS) system
SA40_RS01030	COG1957	nucleoside hydrolase
SA40_RS01050	COG3414	Phosphotransferase system galactitol-specific IIB component
SA40_RS01055	COG3775	system Galactitol-specific IIC component
SA40_RS01060	COG1063	alcohol dehydrogenase
SA40_RS01070	COG1063	alcohol dehydrogenase
SA40_RS01080	COG1063	alcohol dehydrogenase
SA40_RS01085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA40_RS01090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA40_RS01100	COG1063	alcohol dehydrogenase
SA40_RS01105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA40_RS01140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SA40_RS01145	COG2190	(PTS) system
SA40_RS01145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA40_RS01145	COG1263	PTS System
SA40_RS01150	COG2723	6-phospho-beta-galactosidase activity
SA40_RS01155	COG2226	methyltransferase
SA40_RS01210	COG1131	(ABC) transporter
SA40_RS01230	COG1388	LysM domain
SA40_RS01230	COG3942	CHAP domain
SA40_RS01355	COG1114	Component of the transport system for branched-chain amino acids
SA40_RS01360	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SA40_RS01370	COG0577	efflux transmembrane transporter activity
SA40_RS01395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SA40_RS01400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SA40_RS01425	COG3314	Sporulation integral membrane protein YlbJ
SA40_RS01450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SA40_RS01475	COG3037	sugar-specific permease SgaT UlaA
SA40_RS01485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA40_RS01490	COG3711	transcriptional antiterminator
SA40_RS01510	COG2271	Major facilitator Superfamily
SA40_RS01515	COG0346	lactoylglutathione lyase activity
SA40_RS01520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SA40_RS01525	COG0431	NADPH-dependent FMN reductase
SA40_RS01535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SA40_RS01540	COG2822	iron ion transport
SA40_RS01550	COG0672	)-iron permease
SA40_RS01555	COG0805	protein transport
SA40_RS01560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SA40_RS01570	COG1476	TRANSCRIPTIONal
SA40_RS01580	COG1131	(ABC) transporter
SA40_RS01615	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SA40_RS01615	COG0646	methionine synthase
SA40_RS01620	COG0626	cystathionine gamma-synthase activity
SA40_RS01625	COG0626	cystathionine gamma-synthase activity
SA40_RS01630	COG1475	DNA binding
SA40_RS01635	COG0668	transmembrane transport
SA40_RS01640	COG4481	Protein conserved in bacteria
SA40_RS01645	COG0012	GTP binding
SA40_RS01685	COG0582	viral genome integration into host DNA
SA40_RS01755	COG1823	symporter activity
SA40_RS01785	COG2233	PERMEase
SA40_RS01845	COG1683	Conserved Protein
SA40_RS01855	COG3759	membrane
SA40_RS02020	COG0523	cobalamin synthesis protein
SA40_RS02030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SA40_RS02040	COG5609	conserved protein (DUF2294)
SA40_RS02055	COG1647	Serine aminopeptidase, S33
SA40_RS02060	COG0733	neurotransmitter:sodium symporter activity
SA40_RS02065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SA40_RS02070	COG0626	cystathionine gamma-synthase activity
SA40_RS02080	COG2011	ABC-type metal ion transport system permease component
SA40_RS02085	COG1464	Belongs to the NlpA lipoprotein family
SA40_RS02100	COG0494	nUDIX hydrolase
SA40_RS02120	COG0583	DNA-binding transcription factor activity
SA40_RS02125	COG0070	glutamate synthase
SA40_RS02125	COG0067	glutamate synthase
SA40_RS02125	COG0069	glutamate synthase activity
SA40_RS02130	COG0493	'glutamate synthase
SA40_RS02140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA40_RS02140	COG1263	PTS System
SA40_RS02145	COG0366	Alpha amylase catalytic
SA40_RS02150	COG2188	Transcriptional regulator
SA40_RS02160	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SA40_RS02200	COG1982	Orn Lys Arg decarboxylase major
SA40_RS02210	COG3870	Protein conserved in bacteria
SA40_RS02220	COG0470	DNA polymerase III
SA40_RS02225	COG1774	PSP1 C-terminal conserved region
SA40_RS02235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SA40_RS02245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SA40_RS02260	COG0084	hydrolase, TatD family'
SA40_RS02265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SA40_RS02275	COG4466	Protein conserved in bacteria
SA40_RS02285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SA40_RS02290	COG0251	oxidation-reduction process
SA40_RS02335	COG2244	polysaccharide biosynthetic process
SA40_RS02340	COG3956	TIGRFAM MazG family protein
SA40_RS02345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SA40_RS02355	COG1098	S1 RNA binding domain
SA40_RS02370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SA40_RS02395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SA40_RS02470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SA40_RS02485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SA40_RS02495	COG3880	PFAM UvrB UvrC protein
SA40_RS02515	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SA40_RS02520	COG4956	integral membrane protein (PIN domain superfamily)
SA40_RS02540	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SA40_RS02590	COG2813	Specifically methylates the guanine in position
SA40_RS02630	COG1473	amidohydrolase
SA40_RS02660	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SA40_RS02665	COG1428	Deoxynucleoside kinase
SA40_RS02670	COG1428	Deoxynucleoside kinase
SA40_RS02680	COG0561	phosphatase activity
SA40_RS02725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SA40_RS02835	COG0095	Lipoate-protein ligase
SA40_RS02840	COG0083	homoserine kinase activity
SA40_RS02860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SA40_RS02910	COG0667	Aldo Keto reductase
SA40_RS02915	COG0655	NAD(P)H dehydrogenase (quinone) activity
SA40_RS02925	COG1078	dGTPase activity
SA40_RS02960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SA40_RS02965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA40_RS03015	COG4974	Belongs to the 'phage' integrase family
SA40_RS03060	COG0803	Belongs to the bacterial solute-binding protein 9 family
SA40_RS03065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SA40_RS03070	COG1121	(ABC) transporter
SA40_RS03075	COG1321	iron dependent repressor
SA40_RS03085	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SA40_RS03095	COG1682	transport, permease protein
SA40_RS03100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SA40_RS03110	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SA40_RS03115	COG1686	Belongs to the peptidase S11 family
SA40_RS03120	COG1132	(ABC) transporter
SA40_RS03125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SA40_RS03135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SA40_RS03140	COG1120	ATPase activity
SA40_RS03145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA40_RS03150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA40_RS03155	COG2376	Dihydroxyacetone kinase
SA40_RS03165	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SA40_RS03175	COG3949	Membrane
SA40_RS03200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SA40_RS03215	COG1136	(ABC) transporter
SA40_RS03220	COG0577	efflux transmembrane transporter activity
SA40_RS03225	COG1392	Phosphate transport regulator
SA40_RS03230	COG0306	phosphate transporter
SA40_RS03235	COG3942	CHAP domain
SA40_RS03235	COG1388	LysM domain
SA40_RS03245	COG4977	sequence-specific DNA binding
SA40_RS03245	COG1917	Cupin 2, conserved barrel domain protein
SA40_RS03275	COG0583	DNA-binding transcription factor activity
SA40_RS03290	COG2839	Protein conserved in bacteria
SA40_RS03320	COG1611	Belongs to the LOG family
SA40_RS03340	COG4988	ABC transporter
SA40_RS03345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SA40_RS03355	COG0523	cobalamin synthesis protein
SA40_RS03360	COG4989	oxidoreductase activity
SA40_RS03370	COG0471	metal ion transport
SA40_RS03375	COG0415	Belongs to the DNA photolyase family
SA40_RS03405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SA40_RS03410	COG1349	DNA-binding transcription factor activity
SA40_RS03415	COG1105	Belongs to the carbohydrate kinase PfkB family
SA40_RS03420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA40_RS03420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA40_RS03420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA40_RS03430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SA40_RS03435	COG1253	flavin adenine dinucleotide binding
SA40_RS03440	COG0656	L-ascorbic acid biosynthetic process
SA40_RS03445	COG0463	Glycosyl transferase, family 2
SA40_RS03480	COG0720	synthase
SA40_RS03490	COG0512	Glutamine amidotransferase of anthranilate synthase
SA40_RS03490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SA40_RS03495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SA40_RS03530	COG0488	(ABC) transporter
SA40_RS03535	COG0514	ATP-dependent DNA helicase (RecQ)
SA40_RS03540	COG1125	glycine betaine transport
SA40_RS03540	COG0517	IMP dehydrogenase activity
SA40_RS03545	COG1174	glycine betaine transport
SA40_RS03570	COG3104	oligopeptide transport
SA40_RS03590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SA40_RS03595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SA40_RS03605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA40_RS03610	COG4605	iron ion homeostasis
SA40_RS03615	COG4604	ABC transporter, ATP-binding protein
SA40_RS03620	COG4607	ABC-type enterochelin transport system periplasmic component
SA40_RS03675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SA40_RS03680	COG1739	Uncharacterized protein family UPF0029
SA40_RS03690	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SA40_RS03695	COG1040	competence protein
SA40_RS03725	COG3942	CHAP domain
SA40_RS03725	COG1388	LysM domain
SA40_RS03785	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SA40_RS03805	COG0281	malic enzyme
SA40_RS03860	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SA40_RS03865	COG1647	Serine aminopeptidase, S33
SA40_RS03870	COG0557	exoribonuclease II activity
SA40_RS03930	COG1278	Cold shock
SA40_RS03970	COG0406	alpha-ribazole phosphatase activity
SA40_RS03975	COG1279	arginine transmembrane transporter activity
SA40_RS04000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SA40_RS04005	COG1393	Belongs to the ArsC family
SA40_RS04020	COG3878	Protein conserved in bacteria
SA40_RS04030	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SA40_RS04045	COG2011	ABC-type metal ion transport system permease component
SA40_RS04050	COG1464	Belongs to the NlpA lipoprotein family
SA40_RS04055	COG0582	viral genome integration into host DNA
SA40_RS04160	COG5484	DNA packaging
SA40_RS04160	COG3728	DNA packaging
SA40_RS04200	COG0396	ATPase activity
SA40_RS04205	COG0719	Fe-S assembly protein
SA40_RS04215	COG0822	iron-sulfur transferase activity
SA40_RS04235	COG1253	flavin adenine dinucleotide binding
SA40_RS04250	COG1801	Protein of unknown function DUF72
SA40_RS04255	COG0730	response to heat
SA40_RS04270	COG4470	Protein conserved in bacteria
SA40_RS04280	COG2445	Protein of unknown function DUF86
SA40_RS04310	COG1696	Membrane protein involved in D-alanine export
SA40_RS04320	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SA40_RS04325	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SA40_RS04330	COG4837	Protein of unknown function (DUF1462)
SA40_RS04335	COG1252	NADH dehydrogenase
SA40_RS04345	COG0316	Belongs to the HesB IscA family
SA40_RS04355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SA40_RS04360	COG2056	Na+-H+ antiporter family
SA40_RS04365	COG2050	protein possibly involved in aromatic compounds catabolism
SA40_RS04420	COG1098	S1 RNA binding domain
SA40_RS04425	COG1902	pentaerythritol trinitrate reductase activity
SA40_RS04445	COG0584	glycerophosphoryl diester phosphodiesterase
SA40_RS04465	COG0398	Pfam SNARE associated Golgi protein
SA40_RS04505	COG0561	phosphatase activity
SA40_RS04530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SA40_RS04550	COG1881	PFAM PEBP family protein
SA40_RS04580	COG0601	transmembrane transport
SA40_RS04585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA40_RS04590	COG0444	Belongs to the ABC transporter superfamily
SA40_RS04595	COG4608	Belongs to the ABC transporter superfamily
SA40_RS04600	COG4166	transmembrane transport
SA40_RS04605	COG0747	negative chemotaxis
SA40_RS04610	COG0444	Belongs to the ABC transporter superfamily
SA40_RS04615	COG4608	Belongs to the ABC transporter superfamily
SA40_RS04620	COG0601	transmembrane transport
SA40_RS04625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA40_RS04655	COG1164	Oligoendopeptidase f
SA40_RS04665	COG2346	COG2346, Truncated hemoglobins
SA40_RS04680	COG2357	RelA SpoT domain protein
SA40_RS04690	COG0564	pseudouridine synthase activity
SA40_RS04695	COG2239	Acts as a magnesium transporter
SA40_RS04700	COG0569	domain protein
SA40_RS04700	COG0475	glutathione-regulated potassium exporter activity
SA40_RS04710	COG0628	permease
SA40_RS04715	COG1115	amino acid carrier protein
SA40_RS04765	COG0861	Integral membrane protein TerC family
SA40_RS04775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SA40_RS04780	COG0737	Belongs to the 5'-nucleotidase family
SA40_RS04795	COG4903	ComK protein
SA40_RS04810	COG4873	Protein conserved in bacteria
SA40_RS04865	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SA40_RS04875	COG2314	TM2 domain
SA40_RS04880	COG0456	acetyltransferase
SA40_RS04885	COG1575	Belongs to the MenA family. Type 1 subfamily
SA40_RS04890	COG1169	isochorismate synthase
SA40_RS04900	COG2267	carboxylic ester hydrolase activity
SA40_RS04925	COG0436	Aminotransferase
SA40_RS04930	COG3594	Acyltransferase
SA40_RS04960	COG1316	TRANSCRIPTIONal
SA40_RS05005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SA40_RS05020	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SA40_RS05060	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SA40_RS05065	COG4172	Belongs to the ABC transporter superfamily
SA40_RS05070	COG4721	ABC-type cobalt transport system, permease component
SA40_RS05090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SA40_RS05110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SA40_RS05115	COG1271	oxidase subunit
SA40_RS05120	COG1294	oxidase, subunit
SA40_RS05125	COG0569	domain protein
SA40_RS05190	COG1176	ABC-type spermidine putrescine transport system, permease component I
SA40_RS05195	COG1177	transmembrane transport
SA40_RS05200	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SA40_RS05225	COG0483	inositol monophosphate 1-phosphatase activity
SA40_RS05235	COG1217	gtp-binding protein TYPA
SA40_RS05245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SA40_RS05255	COG0772	Belongs to the SEDS family
SA40_RS05290	COG3679	Belongs to the UPF0342 family
SA40_RS05310	COG0742	ribosomal rna small subunit methyltransferase
SA40_RS05370	COG4509	Sortase family
SA40_RS05385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SA40_RS05415	COG1796	DNA polymerase
SA40_RS05415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SA40_RS05440	COG2009	succinate dehydrogenase
SA40_RS05445	COG1053	succinate dehydrogenase
SA40_RS05450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SA40_RS05570	COG1288	antiporter activity
SA40_RS05605	COG1011	Hydrolase
SA40_RS05630	COG4839	cell division protein FtsL
SA40_RS05635	COG0768	penicillin binding
SA40_RS05650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SA40_RS05655	COG0849	cell division
SA40_RS05670	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SA40_RS05680	COG0762	integral membrane protein
SA40_RS05685	COG2302	S4 RNA-binding domain
SA40_RS05690	COG3599	regulation of cell shape
SA40_RS05700	COG2514	catechol 2,3-dioxygenase activity
SA40_RS05720	COG0564	pseudouridine synthase activity
SA40_RS05730	COG2233	PERMEase
SA40_RS05775	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SA40_RS05790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SA40_RS05795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SA40_RS05805	COG2314	TM2 domain
SA40_RS05820	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SA40_RS05820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SA40_RS05830	COG0631	protein serine/threonine phosphatase activity
SA40_RS05845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SA40_RS05860	COG1302	Protein conserved in bacteria
SA40_RS05910	COG1196	nuclear chromosome segregation
SA40_RS05915	COG0552	protein localization to endoplasmic reticulum
SA40_RS05925	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SA40_RS05985	COG2348	transferase activity, transferring amino-acyl groups
SA40_RS05990	COG0758	DNA mediated transformation
SA40_RS06085	COG0195	Participates in both transcription termination and antitermination
SA40_RS06090	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SA40_RS06115	COG0196	riboflavin kinase activity
SA40_RS06140	COG2188	Transcriptional regulator
SA40_RS06145	COG0612	Peptidase, M16
SA40_RS06150	COG0612	Peptidase, M16
SA40_RS06155	COG0300	oxidoreductase activity
SA40_RS06180	COG1546	Belongs to the CinA family
SA40_RS06180	COG1058	Belongs to the CinA family
SA40_RS06200	COG1692	metallophosphoesterase
SA40_RS06205	COG0674	pyruvate-flavodoxin oxidoreductase activity
SA40_RS06205	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SA40_RS06210	COG1013	pyruvate-flavodoxin oxidoreductase activity
SA40_RS06245	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SA40_RS06250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SA40_RS06275	COG1923	regulation of RNA biosynthetic process
SA40_RS06285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SA40_RS06290	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SA40_RS06295	COG0789	Transcriptional regulator
SA40_RS06425	COG1525	nuclease
SA40_RS06440	COG0527	aspartate kinase activity
SA40_RS06445	COG0460	homoserine dehydrogenase
SA40_RS06450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SA40_RS06475	COG0833	amino acid
SA40_RS06505	COG2340	Cysteine-rich secretory protein family
SA40_RS06540	COG4846	Membrane protein involved in cytochrome C biogenesis
SA40_RS06560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SA40_RS06570	COG0824	Thioesterase
SA40_RS06590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SA40_RS06600	COG1115	amino acid carrier protein
SA40_RS06615	COG0628	permease
SA40_RS06640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SA40_RS06650	COG1363	Peptidase, m42
SA40_RS06655	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SA40_RS06660	COG0512	Glutamine amidotransferase of anthranilate synthase
SA40_RS06700	COG0561	phosphatase activity
SA40_RS06745	COG0704	Plays a role in the regulation of phosphate uptake
SA40_RS06755	COG0581	inorganic phosphate transmembrane transporter activity
SA40_RS06760	COG0573	inorganic phosphate transmembrane transporter activity
SA40_RS06775	COG0488	(ABC) transporter
SA40_RS06780	COG0527	aspartate kinase activity
SA40_RS06785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SA40_RS06820	COG2808	Putative FMN-binding domain
SA40_RS06865	COG4548	von Willebrand factor, type A
SA40_RS06870	COG0714	Associated with various cellular activities
SA40_RS06905	COG0671	phosphoesterase, PA-phosphatase related
SA40_RS06985	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SA40_RS07010	COG0531	amino acid
SA40_RS07025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA40_RS07030	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SA40_RS07045	COG0116	Belongs to the methyltransferase superfamily
SA40_RS07075	COG4499	WXG100 protein secretion system (Wss), protein YukC
SA40_RS07075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SA40_RS07085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SA40_RS07090	COG3935	DnaD domain protein
SA40_RS07115	COG0438	transferase activity, transferring glycosyl groups
SA40_RS07120	COG1694	Mazg nucleotide pyrophosphohydrolase
SA40_RS07125	COG2738	Putative neutral zinc metallopeptidase
SA40_RS07170	COG0142	geranyltranstransferase activity
SA40_RS07235	COG0492	ferredoxin-NADP+ reductase activity
SA40_RS07250	COG0514	ATP-dependent DNA helicase (RecQ)
SA40_RS07260	COG1141	Ferredoxin
SA40_RS07295	COG5002	protein histidine kinase activity
SA40_RS07300	COG0745	RESPONSE REGULATOR receiver
SA40_RS07305	COG1187	pseudouridine synthase activity
SA40_RS07330	COG0735	belongs to the Fur family
SA40_RS07335	COG0494	nUDIX hydrolase
SA40_RS07340	COG0667	Aldo Keto reductase
SA40_RS07350	COG4221	oxidoreductase activity
SA40_RS07365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SA40_RS07375	COG0366	Alpha amylase catalytic
SA40_RS07380	COG1609	Transcriptional regulator
SA40_RS07400	COG2195	Cleaves the N-terminal amino acid of tripeptides
SA40_RS07410	COG4129	membrane
SA40_RS07420	COG0508	dehydrogenase complex catalyzes the overall conversion of
SA40_RS07425	COG0022	dehydrogenase e1 component
SA40_RS07430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SA40_RS07435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SA40_RS07440	COG0497	DNA recombination
SA40_RS07470	COG1302	Protein conserved in bacteria
SA40_RS07475	COG0439	Biotin carboxylase
SA40_RS07480	COG0511	ligase activity, forming carbon-carbon bonds
SA40_RS07490	COG0006	proline dipeptidase activity
SA40_RS07505	COG0095	Lipoate-protein ligase
SA40_RS07510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SA40_RS07555	COG4537	Required for transformation and DNA binding
SA40_RS07560	COG1459	type II secretion system
SA40_RS07565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SA40_RS07570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA40_RS07575	COG0011	TIGRFAM Protein of
SA40_RS07580	COG1940	carbohydrate kinase activity
SA40_RS07585	COG4483	Protein conserved in bacteria
SA40_RS07595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SA40_RS07605	COG0768	penicillin binding
SA40_RS07620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SA40_RS07625	COG1121	(ABC) transporter
SA40_RS07635	COG0513	Belongs to the DEAD box helicase family
SA40_RS07645	COG2384	SAM-dependent methyltransferase
SA40_RS07665	COG0517	IMP dehydrogenase activity
SA40_RS07685	COG0295	cytidine deaminase activity
SA40_RS07690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SA40_RS07700	COG1702	phosphate starvation-inducible protein PhoH
SA40_RS07715	COG1030	water channel activity
SA40_RS07725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SA40_RS07730	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SA40_RS07760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SA40_RS07775	COG1466	dna polymerase III delta subunit
SA40_RS07780	COG0658	competence protein
SA40_RS07780	COG2333	competence protein COMEC
SA40_RS07785	COG2131	deaminase
SA40_RS07795	COG2226	methyltransferase
SA40_RS07800	COG0799	negative regulation of ribosome biogenesis
SA40_RS07805	COG1713	HD superfamily hydrolase involved in NAD metabolism
SA40_RS07815	COG1534	Rna-binding protein
SA40_RS07825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SA40_RS07830	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SA40_RS07865	COG3177	Filamentation induced by cAMP protein fic
SA40_RS07870	COG1914	H( )-stimulated, divalent metal cation uptake system
SA40_RS07880	COG0439	Biotin carboxylase
SA40_RS07885	COG0511	ligase activity, forming carbon-carbon bonds
SA40_RS07890	COG1984	allophanate hydrolase subunit 2
SA40_RS07895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SA40_RS07910	COG0826	peptidase U32
SA40_RS07915	COG0826	peptidase U32
SA40_RS07945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SA40_RS07960	COG1104	cysteine desulfurase activity
SA40_RS07965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SA40_RS07975	COG3237	CsbD-like
SA40_RS07980	COG1959	2 iron, 2 sulfur cluster binding
SA40_RS07985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SA40_RS07990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SA40_RS08030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SA40_RS08030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SA40_RS08035	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SA40_RS08035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SA40_RS08040	COG1862	Preprotein translocase
SA40_RS08080	COG2868	ribosomal protein
SA40_RS08120	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SA40_RS08130	COG0285	dihydrofolate synthase activity
SA40_RS08140	COG2818	Glycosylase
SA40_RS08175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SA40_RS08210	COG4112	unkown
SA40_RS08235	COG0833	amino acid
SA40_RS08250	COG1484	DNA-dependent DNA replication
SA40_RS08280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA40_RS08280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SA40_RS08290	COG5002	protein histidine kinase activity
SA40_RS08295	COG0745	RESPONSE REGULATOR receiver
SA40_RS08310	COG0372	Belongs to the citrate synthase family
SA40_RS08315	COG1113	amino acid transport
SA40_RS08340	COG0281	malic enzyme
SA40_RS08350	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SA40_RS08355	COG4109	DRTGG domain
SA40_RS08395	COG0827	DNA restriction-modification system
SA40_RS08405	COG0730	response to heat
SA40_RS08415	COG1104	cysteine desulfurase activity
SA40_RS08425	COG1956	GAF domain-containing protein
SA40_RS08440	COG0584	glycerophosphoryl diester phosphodiesterase
SA40_RS08445	COG1764	response to oxidative stress
SA40_RS08450	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SA40_RS08455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SA40_RS08480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA40_RS08480	COG1263	PTS System
SA40_RS08485	COG0204	Acyl-transferase
SA40_RS08490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SA40_RS08525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA40_RS08530	COG0454	-acetyltransferase
SA40_RS08550	COG1605	Chorismate mutase
SA40_RS08550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SA40_RS08575	COG1674	ftsk spoiiie
SA40_RS08580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SA40_RS08590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SA40_RS08595	COG1363	Peptidase, m42
SA40_RS08605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SA40_RS08615	COG0510	thiamine kinase activity
SA40_RS08635	COG1187	pseudouridine synthase activity
SA40_RS08640	COG2244	polysaccharide biosynthetic process
SA40_RS08645	COG2081	HI0933 family
SA40_RS08665	COG2814	Major facilitator Superfamily
SA40_RS08670	COG1242	4 iron, 4 sulfur cluster binding
SA40_RS08675	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SA40_RS08685	COG2267	carboxylic ester hydrolase activity
SA40_RS08715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SA40_RS08715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SA40_RS08740	COG5632	N-Acetylmuramoyl-L-alanine amidase
SA40_RS08740	COG4193	domain, Protein
SA40_RS08740	COG3266	domain, Protein
SA40_RS08775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SA40_RS08795	COG0656	L-ascorbic acid biosynthetic process
SA40_RS08815	COG1506	peptidase
SA40_RS08820	COG2816	NAD+ diphosphatase activity
SA40_RS08915	COG0860	N-Acetylmuramoyl-L-alanine amidase
SA40_RS08915	COG1388	LysM domain
SA40_RS08995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SA40_RS09025	COG1131	(ABC) transporter
SA40_RS09030	COG0537	adenosine 5'-monophosphoramidase activity
SA40_RS09060	COG0420	3'-5' exonuclease activity
SA40_RS09085	COG2197	response regulator
SA40_RS09090	COG2203	Gaf domain
SA40_RS09090	COG4585	Histidine kinase
SA40_RS09095	COG0564	pseudouridine synthase activity
SA40_RS09135	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SA40_RS09140	COG1126	abc transporter atp-binding protein
SA40_RS09145	COG0765	amino acid transport
SA40_RS09310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SA40_RS09315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SA40_RS09325	COG4129	membrane
SA40_RS09345	COG1194	a g-specific adenine glycosylase
SA40_RS09350	COG1988	membrane-bound metal-dependent
SA40_RS09365	COG1134	teichoic acid transport
SA40_RS09365	COG1388	LysM domain
SA40_RS09395	COG0535	radical SAM domain protein
SA40_RS09400	COG1607	acyl-coa hydrolase
SA40_RS09405	COG2309	aminopeptidase activity
SA40_RS09425	COG1295	ribonuclease BN
SA40_RS09540	COG4851	CamS sex pheromone cAM373 precursor
SA40_RS09560	COG4496	protein, YerC YecD
SA40_RS09595	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SA40_RS09605	COG0077	Prephenate dehydratase
SA40_RS09615	COG0471	metal ion transport
SA40_RS09625	COG1335	isochorismatase
SA40_RS09640	COG1012	belongs to the aldehyde dehydrogenase family
SA40_RS09690	COG1131	(ABC) transporter
SA40_RS09705	COG1725	Transcriptional regulator
SA40_RS09760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SA40_RS09825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SA40_RS09830	COG1621	beta-fructofuranosidase activity
SA40_RS09835	COG1609	Transcriptional regulator
SA40_RS09840	COG0004	ammonium transporteR
SA40_RS09845	COG0425	Belongs to the sulfur carrier protein TusA family
SA40_RS09850	COG2391	methyltransferase activity
SA40_RS09860	COG0488	(ABC) transporter
SA40_RS09875	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SA40_RS09885	COG0456	acetyltransferase
SA40_RS09890	COG1214	PFAM Peptidase M22, glycoprotease
SA40_RS09895	COG0802	atpase or kinase
SA40_RS09910	COG0028	Belongs to the TPP enzyme family
SA40_RS09985	COG2183	response to ionizing radiation
SA40_RS09990	COG1191	sigma factor activity
SA40_RS10000	COG1366	Belongs to the anti-sigma-factor antagonist family
SA40_RS10005	COG2208	phosphoserine phosphatase activity
SA40_RS10040	COG3428	Bacterial PH domain
SA40_RS10070	COG2205	protein histidine kinase activity
SA40_RS10075	COG0745	RESPONSE REGULATOR receiver
SA40_RS10085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SA40_RS10095	COG0772	Belongs to the SEDS family
SA40_RS10110	COG1937	Protein conserved in bacteria
SA40_RS10120	COG1418	mRNA catabolic process
SA40_RS10165	COG0629	single-stranded DNA binding
SA40_RS10255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SA40_RS10280	COG0009	L-threonylcarbamoyladenylate synthase
SA40_RS10285	COG2890	protein-(glutamine-N5) methyltransferase activity
SA40_RS10305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SA40_RS10345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SA40_RS10400	COG0813	purine-nucleoside phosphorylase activity
SA40_RS10405	COG0783	Belongs to the Dps family
SA40_RS10425	COG1482	cell wall glycoprotein biosynthetic process
SA40_RS10430	COG0702	epimerase
SA40_RS10435	COG0640	Transcriptional regulator
SA40_RS10475	COG0561	phosphatase activity
SA40_RS10480	COG1119	ATPase activity
SA40_RS10495	COG3711	transcriptional antiterminator
SA40_RS10525	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SA40_RS10585	COG0489	protein tyrosine kinase activity
SA40_RS10605	COG1272	protein, Hemolysin III
SA40_RS10615	COG1988	membrane-bound metal-dependent
SA40_RS10625	COG3314	Sporulation integral membrane protein YlbJ
SA40_RS10630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA40_RS10635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SA40_RS10640	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SA40_RS10650	COG3457	Alanine racemase
SA40_RS10655	COG4264	IucA IucC family
SA40_RS10660	COG2814	Major facilitator Superfamily
SA40_RS10685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SA40_RS10695	COG2130	NADP-dependent
SA40_RS10760	COG0656	L-ascorbic acid biosynthetic process
SA40_RS10765	COG0789	Transcriptional regulator
SA40_RS10775	COG5492	domain, Protein
SA40_RS10780	COG2378	regulation of single-species biofilm formation
SA40_RS10785	COG0693	protein deglycase activity
SA40_RS10795	COG3527	Alpha-acetolactate decarboxylase
SA40_RS10800	COG0028	Belongs to the TPP enzyme family
SA40_RS10880	COG0201	protein transport
SA40_RS10995	COG2252	PERMEase
SA40_RS11040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SA40_RS11100	COG1763	Mo-molybdopterin cofactor biosynthetic process
SA40_RS11120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SA40_RS11125	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SA40_RS11130	COG4149	molybdate abc transporter
SA40_RS11135	COG0725	ABC transporter, periplasmic molybdate-binding protein
SA40_RS11150	COG1268	BioY protein
SA40_RS11165	COG1960	acyl-CoA dehydrogenase activity
SA40_RS11170	COG4413	Urea transporter
SA40_RS11245	COG1757	Na H antiporter
SA40_RS11260	COG3942	CHAP domain
SA40_RS11305	COG1316	TRANSCRIPTIONal
SA40_RS11335	COG1113	amino acid transport
SA40_RS11355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SA40_RS11360	COG0385	Bile acid
SA40_RS11370	COG1263	PTS System
SA40_RS11370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA40_RS11375	COG1737	Transcriptional regulator
SA40_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
SA40_RS11400	COG1473	amidohydrolase
SA40_RS11415	COG0583	DNA-binding transcription factor activity
SA40_RS11435	COG2258	MOSC domain
SA40_RS11455	COG1668	transmembrane transport
SA40_RS11460	COG4152	abc transporter atp-binding protein
SA40_RS11465	COG3152	Membrane
SA40_RS11475	COG0786	glutamate:sodium symporter activity
SA40_RS11485	COG0598	Magnesium transport protein CorA
SA40_RS11500	COG0657	acetylesterase activity
SA40_RS11510	COG2814	Major facilitator Superfamily
SA40_RS11515	COG1566	PFAM secretion protein HlyD family protein
SA40_RS11530	COG2814	Major facilitator Superfamily
SA40_RS11595	COG1131	(ABC) transporter
SA40_RS11610	COG1620	l-lactate permease
SA40_RS11630	COG0604	alcohol dehydrogenase
SA40_RS11660	COG1511	domain protein
SA40_RS11675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SA40_RS11675	COG1263	PTS System
SA40_RS11690	COG3871	stress protein (general stress protein 26)
SA40_RS11730	COG0789	Transcriptional regulator
SA40_RS11750	COG2181	nitrate reductase activity
SA40_RS11760	COG1140	nitrate reductase beta subunit
SA40_RS11765	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SA40_RS11775	COG2146	nitrite reductase [NAD(P)H] activity
SA40_RS11780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SA40_RS11790	COG0454	-acetyltransferase
SA40_RS11795	COG2116	formate transmembrane transporter activity
SA40_RS11810	COG0803	Belongs to the bacterial solute-binding protein 9 family
SA40_RS11810	COG3443	Belongs to the bacterial solute-binding protein 9 family
SA40_RS11845	COG1126	abc transporter atp-binding protein
SA40_RS11850	COG0765	amino acid transport
SA40_RS11855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SA40_RS11860	COG2814	Major facilitator Superfamily
SA40_RS11875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SA40_RS11920	COG0156	8-amino-7-oxononanoate synthase activity
SA40_RS11930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SA40_RS11935	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SA40_RS11950	COG1132	(ABC) transporter
SA40_RS11955	COG2375	cellular response to nickel ion
SA40_RS11955	COG1132	(ABC) transporter
SA40_RS11970	COG1929	Belongs to the glycerate kinase type-1 family
SA40_RS11980	COG2814	Major facilitator Superfamily
SA40_RS11995	COG1408	metallophosphoesterase
SA40_RS12000	COG1113	amino acid transport
SA40_RS12015	COG0531	amino acid
SA40_RS12040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SA40_RS12050	COG1174	glycine betaine transport
SA40_RS12060	COG1174	glycine betaine transport
SA40_RS12080	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SA40_RS12085	COG0531	amino acid
SA40_RS12090	COG2272	Belongs to the type-B carboxylesterase lipase family
SA40_RS12095	COG2814	Major facilitator Superfamily
SA40_RS12100	COG0390	transport system, permease component
SA40_RS12105	COG4619	ABC transporter
SA40_RS12110	COG1363	Peptidase, m42
SA40_RS12115	COG4808	Protein conserved in bacteria
SA40_RS12120	COG0069	glutamate synthase activity
SA40_RS12135	COG1124	(ABC) transporter
SA40_RS12145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SA40_RS12150	COG0601	transmembrane transport
SA40_RS12155	COG0747	negative chemotaxis
SA40_RS12180	COG1028	Short-chain dehydrogenase reductase Sdr
SA40_RS12185	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SA40_RS12190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SA40_RS12290	COG0494	nUDIX hydrolase
SA40_RS12345	COG1846	Transcriptional regulator
SA40_RS12380	COG1070	Carbohydrate kinase
SA40_RS12385	COG1802	Transcriptional regulator
SA40_RS12390	COG0789	Transcriptional regulator
SA40_RS12395	COG2357	RelA SpoT domain protein
SA40_RS12400	COG4876	unkown
SA40_RS12410	COG2271	Major facilitator Superfamily
SA40_RS12415	COG0586	Pfam SNARE associated Golgi protein
SA40_RS12425	COG1131	(ABC) transporter
SA40_RS12435	COG1073	alpha beta
SA40_RS12445	COG1073	alpha beta
SA40_RS12470	COG3949	Membrane
SA40_RS12475	COG0400	carboxylic ester hydrolase activity
SA40_RS12480	COG0346	lactoylglutathione lyase activity
SA40_RS12485	COG1846	Transcriptional regulator
SA40_RS12500	COG2514	catechol 2,3-dioxygenase activity
SA40_RS12515	COG0561	phosphatase activity
SA40_RS12520	COG1131	(ABC) transporter
SA40_RS12530	COG3764	Sortase (surface protein transpeptidase)
SA40_RS12550	COG1760	l-serine dehydratase
SA40_RS12555	COG1760	l-serine dehydratase
SA40_RS12570	COG0697	spore germination
SA40_RS12575	COG0657	acetylesterase activity
SA40_RS12595	COG0028	Belongs to the TPP enzyme family
SA40_RS12610	COG0583	DNA-binding transcription factor activity
SA40_RS12620	COG3942	CHAP domain
SA40_RS12630	COG3425	synthase
SA40_RS12640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SA40_RS12665	COG2409	Drug exporters of the RND superfamily
SA40_RS12710	COG0436	Aminotransferase
SA40_RS12750	COG0456	acetyltransferase
SA40_RS12820	COG0596	Alpha beta hydrolase
SA40_RS12855	COG3001	Fructosamine kinase
SA40_RS12860	COG0167	dihydroorotate dehydrogenase activity
SA40_RS12930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SA40_RS12935	COG3527	Alpha-acetolactate decarboxylase
SA40_RS12950	COG0531	amino acid
SA40_RS12980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SA40_RS13000	COG1012	belongs to the aldehyde dehydrogenase family
SA40_RS13010	COG1510	regulation of RNA biosynthetic process
SA40_RS13015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SA40_RS13040	COG2851	Citrate transporter
SA40_RS13050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SA40_RS13060	COG0386	Belongs to the glutathione peroxidase family
SA40_RS13085	COG1136	(ABC) transporter
SA40_RS13090	COG2205	protein histidine kinase activity
SA40_RS13095	COG0745	RESPONSE REGULATOR receiver
SA40_RS13110	COG1785	Belongs to the alkaline phosphatase family
SA40_RS13115	COG1846	Transcriptional regulator
SA40_RS13160	COG1438	arginine binding
SA40_RS13180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA40_RS13180	COG3711	transcriptional antiterminator
SA40_RS13185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SA40_RS13185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA40_RS13185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SA40_RS13190	COG1482	cell wall glycoprotein biosynthetic process
SA40_RS13200	COG3942	CHAP domain
SA40_RS13200	COG1705	Flagellar rod assembly protein muramidase FlgJ
SA40_RS13205	COG3433	isochorismatase activity
SA40_RS13205	COG1535	isochorismatase
SA40_RS13220	COG0438	transferase activity, transferring glycosyl groups
SA40_RS13235	COG1073	alpha beta
SA40_RS13255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SA40_RS13285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SA40_RS13385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SA40_RS13470	COG0471	metal ion transport
SA40_RS13475	COG2962	Rard protein
SA40_RS13485	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SA40_RS13500	COG1136	(ABC) transporter
SA40_RS13505	COG0577	efflux transmembrane transporter activity
SA40_RS13530	COG1278	Cold shock
SA40_RS13550	COG1475	DNA binding