locus-tag	class	description
AC807_RS00070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AC807_RS00190	COG1506	peptidase
AC807_RS00215	COG0656	L-ascorbic acid biosynthetic process
AC807_RS00245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AC807_RS00275	COG5632	N-Acetylmuramoyl-L-alanine amidase
AC807_RS00275	COG4193	domain, Protein
AC807_RS00275	COG3266	domain, Protein
AC807_RS00300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AC807_RS00300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AC807_RS00330	COG2267	carboxylic ester hydrolase activity
AC807_RS00350	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AC807_RS00355	COG1242	4 iron, 4 sulfur cluster binding
AC807_RS00360	COG2814	Major facilitator Superfamily
AC807_RS00380	COG2081	HI0933 family
AC807_RS00385	COG2244	polysaccharide biosynthetic process
AC807_RS00390	COG1187	pseudouridine synthase activity
AC807_RS00410	COG0510	thiamine kinase activity
AC807_RS00420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC807_RS00430	COG1363	Peptidase, m42
AC807_RS00435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC807_RS00445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AC807_RS00450	COG1674	ftsk spoiiie
AC807_RS00475	COG1605	Chorismate mutase
AC807_RS00475	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AC807_RS00495	COG0454	-acetyltransferase
AC807_RS00500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC807_RS00530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AC807_RS00535	COG0204	Acyl-transferase
AC807_RS00540	COG1263	PTS System
AC807_RS00540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC807_RS00555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AC807_RS00560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AC807_RS00565	COG1764	response to oxidative stress
AC807_RS00570	COG0584	glycerophosphoryl diester phosphodiesterase
AC807_RS00585	COG1956	GAF domain-containing protein
AC807_RS00600	COG1104	cysteine desulfurase activity
AC807_RS00620	COG0827	DNA restriction-modification system
AC807_RS00660	COG4109	DRTGG domain
AC807_RS00665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AC807_RS00675	COG0281	malic enzyme
AC807_RS00710	COG1113	amino acid transport
AC807_RS00715	COG0372	Belongs to the citrate synthase family
AC807_RS00730	COG0745	RESPONSE REGULATOR receiver
AC807_RS00735	COG5002	protein histidine kinase activity
AC807_RS00745	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AC807_RS00745	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AC807_RS00775	COG1484	DNA-dependent DNA replication
AC807_RS00790	COG0833	amino acid
AC807_RS00815	COG4112	unkown
AC807_RS00850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AC807_RS00885	COG2818	Glycosylase
AC807_RS00895	COG0285	dihydrofolate synthase activity
AC807_RS00905	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AC807_RS00950	COG2868	ribosomal protein
AC807_RS00990	COG1862	Preprotein translocase
AC807_RS00995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AC807_RS00995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AC807_RS01000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AC807_RS01000	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AC807_RS01040	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AC807_RS01045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AC807_RS01050	COG1959	2 iron, 2 sulfur cluster binding
AC807_RS01065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AC807_RS01070	COG1104	cysteine desulfurase activity
AC807_RS01085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AC807_RS01115	COG0826	peptidase U32
AC807_RS01120	COG0826	peptidase U32
AC807_RS01135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AC807_RS01140	COG1984	allophanate hydrolase subunit 2
AC807_RS01145	COG0511	ligase activity, forming carbon-carbon bonds
AC807_RS01150	COG0439	Biotin carboxylase
AC807_RS01160	COG1914	H( )-stimulated, divalent metal cation uptake system
AC807_RS01165	COG3177	Filamentation induced by cAMP protein fic
AC807_RS01190	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AC807_RS01195	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AC807_RS01205	COG1534	Rna-binding protein
AC807_RS01215	COG1713	HD superfamily hydrolase involved in NAD metabolism
AC807_RS01220	COG0799	negative regulation of ribosome biogenesis
AC807_RS01225	COG2226	methyltransferase
AC807_RS01235	COG2131	deaminase
AC807_RS01240	COG0658	competence protein
AC807_RS01240	COG2333	competence protein COMEC
AC807_RS01245	COG1466	dna polymerase III delta subunit
AC807_RS01265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AC807_RS01295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AC807_RS01300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AC807_RS01310	COG1030	water channel activity
AC807_RS01325	COG1702	phosphate starvation-inducible protein PhoH
AC807_RS01340	COG0295	cytidine deaminase activity
AC807_RS01360	COG0517	IMP dehydrogenase activity
AC807_RS01380	COG2384	SAM-dependent methyltransferase
AC807_RS01390	COG0513	Belongs to the DEAD box helicase family
AC807_RS01400	COG1121	(ABC) transporter
AC807_RS01405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AC807_RS01420	COG0768	penicillin binding
AC807_RS01430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AC807_RS01440	COG4483	Protein conserved in bacteria
AC807_RS01445	COG1940	carbohydrate kinase activity
AC807_RS01450	COG0011	TIGRFAM Protein of
AC807_RS01455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC807_RS01460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AC807_RS01465	COG1459	type II secretion system
AC807_RS01470	COG4537	Required for transformation and DNA binding
AC807_RS01515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AC807_RS01520	COG0095	Lipoate-protein ligase
AC807_RS01535	COG0006	proline dipeptidase activity
AC807_RS01545	COG0511	ligase activity, forming carbon-carbon bonds
AC807_RS01550	COG0439	Biotin carboxylase
AC807_RS01555	COG1302	Protein conserved in bacteria
AC807_RS01585	COG0497	DNA recombination
AC807_RS01590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC807_RS01595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AC807_RS01600	COG0022	dehydrogenase e1 component
AC807_RS01605	COG0508	dehydrogenase complex catalyzes the overall conversion of
AC807_RS01615	COG4129	membrane
AC807_RS01625	COG2195	Cleaves the N-terminal amino acid of tripeptides
AC807_RS01645	COG1609	Transcriptional regulator
AC807_RS01650	COG0366	Alpha amylase catalytic
AC807_RS01660	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AC807_RS01675	COG4221	oxidoreductase activity
AC807_RS01685	COG0667	Aldo Keto reductase
AC807_RS01690	COG0494	nUDIX hydrolase
AC807_RS01695	COG0735	belongs to the Fur family
AC807_RS01720	COG1187	pseudouridine synthase activity
AC807_RS01725	COG0745	RESPONSE REGULATOR receiver
AC807_RS01730	COG5002	protein histidine kinase activity
AC807_RS01745	COG0582	viral genome integration into host DNA
AC807_RS02000	COG3953	SLT domain
AC807_RS02000	COG5280	Phage tail tape measure protein TP901
AC807_RS02050	COG0860	N-Acetylmuramoyl-L-alanine amidase
AC807_RS02050	COG1388	LysM domain
AC807_RS02100	COG1141	Ferredoxin
AC807_RS02110	COG0514	ATP-dependent DNA helicase (RecQ)
AC807_RS02125	COG0492	ferredoxin-NADP+ reductase activity
AC807_RS02190	COG0142	geranyltranstransferase activity
AC807_RS02230	COG4347	Protein of unknown function (DUF1405)
AC807_RS02235	COG2738	Putative neutral zinc metallopeptidase
AC807_RS02240	COG1694	Mazg nucleotide pyrophosphohydrolase
AC807_RS02245	COG0438	transferase activity, transferring glycosyl groups
AC807_RS02270	COG3935	DnaD domain protein
AC807_RS02275	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AC807_RS02285	COG4499	WXG100 protein secretion system (Wss), protein YukC
AC807_RS02285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AC807_RS02315	COG0116	Belongs to the methyltransferase superfamily
AC807_RS02335	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AC807_RS02340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AC807_RS02355	COG0531	amino acid
AC807_RS02385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AC807_RS02395	COG1413	lyase activity
AC807_RS02465	COG0671	phosphoesterase, PA-phosphatase related
AC807_RS02520	COG4548	von Willebrand factor, type A
AC807_RS02605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AC807_RS02610	COG0527	aspartate kinase activity
AC807_RS02615	COG0488	(ABC) transporter
AC807_RS02640	COG0573	inorganic phosphate transmembrane transporter activity
AC807_RS02645	COG0581	inorganic phosphate transmembrane transporter activity
AC807_RS02655	COG0704	Plays a role in the regulation of phosphate uptake
AC807_RS02700	COG0561	phosphatase activity
AC807_RS02740	COG0512	Glutamine amidotransferase of anthranilate synthase
AC807_RS02745	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AC807_RS02750	COG1363	Peptidase, m42
AC807_RS02760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AC807_RS02780	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AC807_RS02780	COG0392	lysyltransferase activity
AC807_RS02785	COG0628	permease
AC807_RS02800	COG1115	amino acid carrier protein
AC807_RS02830	COG0824	Thioesterase
AC807_RS02840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC807_RS02860	COG4846	Membrane protein involved in cytochrome C biogenesis
AC807_RS02895	COG2340	Cysteine-rich secretory protein family
AC807_RS02925	COG0833	amino acid
AC807_RS02950	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AC807_RS02955	COG0460	homoserine dehydrogenase
AC807_RS02960	COG0527	aspartate kinase activity
AC807_RS02975	COG1525	nuclease
AC807_RS02985	COG2197	response regulator
AC807_RS03000	COG1131	(ABC) transporter
AC807_RS03120	COG0789	Transcriptional regulator
AC807_RS03125	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AC807_RS03130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AC807_RS03140	COG1923	regulation of RNA biosynthetic process
AC807_RS03165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AC807_RS03170	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AC807_RS03205	COG1013	pyruvate-flavodoxin oxidoreductase activity
AC807_RS03210	COG0674	pyruvate-flavodoxin oxidoreductase activity
AC807_RS03210	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AC807_RS03215	COG1692	metallophosphoesterase
AC807_RS03235	COG1546	Belongs to the CinA family
AC807_RS03235	COG1058	Belongs to the CinA family
AC807_RS03255	COG0300	oxidoreductase activity
AC807_RS03260	COG0612	Peptidase, M16
AC807_RS03265	COG0612	Peptidase, M16
AC807_RS03270	COG2188	Transcriptional regulator
AC807_RS03295	COG0196	riboflavin kinase activity
AC807_RS03320	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AC807_RS03325	COG0195	Participates in both transcription termination and antitermination
AC807_RS03420	COG0758	DNA mediated transformation
AC807_RS03485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AC807_RS03495	COG0552	protein localization to endoplasmic reticulum
AC807_RS03500	COG1196	nuclear chromosome segregation
AC807_RS03540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AC807_RS03550	COG1302	Protein conserved in bacteria
AC807_RS03565	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AC807_RS03580	COG0631	protein serine/threonine phosphatase activity
AC807_RS03590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AC807_RS03590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AC807_RS03605	COG2314	TM2 domain
AC807_RS03615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AC807_RS03620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AC807_RS03635	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AC807_RS03680	COG2233	PERMEase
AC807_RS03690	COG0564	pseudouridine synthase activity
AC807_RS03705	COG2514	catechol 2,3-dioxygenase activity
AC807_RS03715	COG3599	regulation of cell shape
AC807_RS03720	COG2302	S4 RNA-binding domain
AC807_RS03725	COG0762	integral membrane protein
AC807_RS03735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AC807_RS03750	COG0849	cell division
AC807_RS03755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AC807_RS03770	COG0768	penicillin binding
AC807_RS03775	COG4839	cell division protein FtsL
AC807_RS03800	COG1011	Hydrolase
AC807_RS03835	COG1288	antiporter activity
AC807_RS03955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AC807_RS03960	COG1053	succinate dehydrogenase
AC807_RS03965	COG2009	succinate dehydrogenase
AC807_RS03990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AC807_RS03990	COG1796	DNA polymerase
AC807_RS04020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AC807_RS04035	COG4509	Sortase family
AC807_RS04095	COG0742	ribosomal rna small subunit methyltransferase
AC807_RS04115	COG3679	Belongs to the UPF0342 family
AC807_RS04150	COG0772	Belongs to the SEDS family
AC807_RS04160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AC807_RS04170	COG1217	gtp-binding protein TYPA
AC807_RS04180	COG0483	inositol monophosphate 1-phosphatase activity
AC807_RS04205	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AC807_RS04210	COG1177	transmembrane transport
AC807_RS04215	COG1176	ABC-type spermidine putrescine transport system, permease component I
AC807_RS04285	COG0569	domain protein
AC807_RS04290	COG1294	oxidase, subunit
AC807_RS04295	COG1271	oxidase subunit
AC807_RS04320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AC807_RS04340	COG4721	ABC-type cobalt transport system, permease component
AC807_RS04345	COG4172	Belongs to the ABC transporter superfamily
AC807_RS04350	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AC807_RS04390	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AC807_RS04405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AC807_RS04445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AC807_RS04450	COG1316	TRANSCRIPTIONal
AC807_RS04480	COG3594	Acyltransferase
AC807_RS04485	COG0436	Aminotransferase
AC807_RS04510	COG2267	carboxylic ester hydrolase activity
AC807_RS04520	COG1169	isochorismate synthase
AC807_RS04525	COG1575	Belongs to the MenA family. Type 1 subfamily
AC807_RS04530	COG0456	acetyltransferase
AC807_RS04535	COG2314	TM2 domain
AC807_RS04545	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AC807_RS04600	COG4873	Protein conserved in bacteria
AC807_RS04615	COG4903	ComK protein
AC807_RS04630	COG0737	Belongs to the 5'-nucleotidase family
AC807_RS04635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AC807_RS04645	COG0861	Integral membrane protein TerC family
AC807_RS04685	COG1115	amino acid carrier protein
AC807_RS04690	COG0628	permease
AC807_RS04700	COG0569	domain protein
AC807_RS04700	COG0475	glutathione-regulated potassium exporter activity
AC807_RS04705	COG2239	Acts as a magnesium transporter
AC807_RS04710	COG0564	pseudouridine synthase activity
AC807_RS04720	COG2357	RelA SpoT domain protein
AC807_RS04735	COG2346	COG2346, Truncated hemoglobins
AC807_RS04745	COG1164	Oligoendopeptidase f
AC807_RS04770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC807_RS04775	COG0601	transmembrane transport
AC807_RS04785	COG0444	Belongs to the ABC transporter superfamily
AC807_RS04790	COG0747	negative chemotaxis
AC807_RS04795	COG4166	transmembrane transport
AC807_RS04800	COG4608	Belongs to the ABC transporter superfamily
AC807_RS04805	COG0444	Belongs to the ABC transporter superfamily
AC807_RS04810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC807_RS04815	COG0601	transmembrane transport
AC807_RS04845	COG1881	PFAM PEBP family protein
AC807_RS04860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AC807_RS04885	COG0561	phosphatase activity
AC807_RS04925	COG0398	Pfam SNARE associated Golgi protein
AC807_RS04945	COG0584	glycerophosphoryl diester phosphodiesterase
AC807_RS04965	COG1902	pentaerythritol trinitrate reductase activity
AC807_RS04970	COG1098	S1 RNA binding domain
AC807_RS05025	COG2050	protein possibly involved in aromatic compounds catabolism
AC807_RS05030	COG2056	Na+-H+ antiporter family
AC807_RS05035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AC807_RS05045	COG0316	Belongs to the HesB IscA family
AC807_RS05055	COG1252	NADH dehydrogenase
AC807_RS05060	COG4837	Protein of unknown function (DUF1462)
AC807_RS05065	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AC807_RS05070	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AC807_RS05080	COG1696	Membrane protein involved in D-alanine export
AC807_RS05110	COG2445	Protein of unknown function DUF86
AC807_RS05120	COG4470	Protein conserved in bacteria
AC807_RS05135	COG0730	response to heat
AC807_RS05140	COG1801	Protein of unknown function DUF72
AC807_RS05155	COG1253	flavin adenine dinucleotide binding
AC807_RS05175	COG0822	iron-sulfur transferase activity
AC807_RS05185	COG0719	Fe-S assembly protein
AC807_RS05190	COG0396	ATPase activity
AC807_RS05290	COG0582	viral genome integration into host DNA
AC807_RS05295	COG1464	Belongs to the NlpA lipoprotein family
AC807_RS05300	COG2011	ABC-type metal ion transport system permease component
AC807_RS05315	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AC807_RS05325	COG3878	Protein conserved in bacteria
AC807_RS05340	COG1393	Belongs to the ArsC family
AC807_RS05345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AC807_RS05370	COG1279	arginine transmembrane transporter activity
AC807_RS05375	COG0406	alpha-ribazole phosphatase activity
AC807_RS05415	COG1278	Cold shock
AC807_RS05485	COG0557	exoribonuclease II activity
AC807_RS05490	COG1647	Serine aminopeptidase, S33
AC807_RS05495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AC807_RS05560	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AC807_RS05620	COG3942	CHAP domain
AC807_RS05620	COG1388	LysM domain
AC807_RS05650	COG1040	competence protein
AC807_RS05655	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AC807_RS05665	COG1739	Uncharacterized protein family UPF0029
AC807_RS05670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AC807_RS05725	COG4607	ABC-type enterochelin transport system periplasmic component
AC807_RS05730	COG4604	ABC transporter, ATP-binding protein
AC807_RS05735	COG4605	iron ion homeostasis
AC807_RS05740	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC807_RS05755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AC807_RS05760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AC807_RS05780	COG3104	oligopeptide transport
AC807_RS05805	COG1174	glycine betaine transport
AC807_RS05810	COG1125	glycine betaine transport
AC807_RS05810	COG0517	IMP dehydrogenase activity
AC807_RS05820	COG0488	(ABC) transporter
AC807_RS05855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AC807_RS05860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AC807_RS05860	COG0512	Glutamine amidotransferase of anthranilate synthase
AC807_RS05870	COG0720	synthase
AC807_RS05905	COG0463	Glycosyl transferase, family 2
AC807_RS05910	COG0656	L-ascorbic acid biosynthetic process
AC807_RS05915	COG1253	flavin adenine dinucleotide binding
AC807_RS05920	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AC807_RS05930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC807_RS05930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC807_RS05930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC807_RS05935	COG1105	Belongs to the carbohydrate kinase PfkB family
AC807_RS05940	COG1349	DNA-binding transcription factor activity
AC807_RS05945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AC807_RS05975	COG0415	Belongs to the DNA photolyase family
AC807_RS05980	COG0471	metal ion transport
AC807_RS05990	COG4989	oxidoreductase activity
AC807_RS05995	COG0523	cobalamin synthesis protein
AC807_RS06005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AC807_RS06010	COG4988	ABC transporter
AC807_RS06030	COG1611	Belongs to the LOG family
AC807_RS06060	COG2839	Protein conserved in bacteria
AC807_RS06065	COG2814	Major facilitator Superfamily
AC807_RS06075	COG0583	DNA-binding transcription factor activity
AC807_RS06105	COG4977	sequence-specific DNA binding
AC807_RS06105	COG1917	Cupin 2, conserved barrel domain protein
AC807_RS06115	COG3942	CHAP domain
AC807_RS06115	COG1388	LysM domain
AC807_RS06120	COG0306	phosphate transporter
AC807_RS06125	COG1392	Phosphate transport regulator
AC807_RS06130	COG0577	efflux transmembrane transporter activity
AC807_RS06135	COG1136	(ABC) transporter
AC807_RS06150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AC807_RS06175	COG3949	Membrane
AC807_RS06185	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AC807_RS06195	COG2376	Dihydroxyacetone kinase
AC807_RS06200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC807_RS06205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC807_RS06210	COG1120	ATPase activity
AC807_RS06215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AC807_RS06225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AC807_RS06230	COG1132	(ABC) transporter
AC807_RS06235	COG1686	Belongs to the peptidase S11 family
AC807_RS06240	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AC807_RS06245	COG1216	Glycosyl transferase, family 2
AC807_RS06250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AC807_RS06255	COG1682	transport, permease protein
AC807_RS06265	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AC807_RS06275	COG1321	iron dependent repressor
AC807_RS06280	COG1121	(ABC) transporter
AC807_RS06285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AC807_RS06290	COG0803	Belongs to the bacterial solute-binding protein 9 family
AC807_RS06335	COG4974	Belongs to the 'phage' integrase family
AC807_RS06370	COG2946	Replication initiation factor
AC807_RS06390	COG0433	COG0433 Predicted ATPase
AC807_RS06395	COG1674	ftsk spoiiie
AC807_RS06425	COG2826	transposase and inactivated derivatives, IS30 family
AC807_RS06465	COG4139	cobalamin transport
AC807_RS06470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AC807_RS06505	COG1078	dGTPase activity
AC807_RS06515	COG0655	NAD(P)H dehydrogenase (quinone) activity
AC807_RS06520	COG0667	Aldo Keto reductase
AC807_RS06605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AC807_RS06625	COG0083	homoserine kinase activity
AC807_RS06630	COG0095	Lipoate-protein ligase
AC807_RS06735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AC807_RS06775	COG0561	phosphatase activity
AC807_RS06785	COG1428	Deoxynucleoside kinase
AC807_RS06790	COG1428	Deoxynucleoside kinase
AC807_RS06795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AC807_RS06825	COG1473	amidohydrolase
AC807_RS06865	COG2813	Specifically methylates the guanine in position
AC807_RS06915	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AC807_RS06935	COG4956	integral membrane protein (PIN domain superfamily)
AC807_RS06940	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AC807_RS06960	COG3880	PFAM UvrB UvrC protein
AC807_RS06970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AC807_RS06985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC807_RS07080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AC807_RS07105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AC807_RS07120	COG1098	S1 RNA binding domain
AC807_RS07130	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AC807_RS07135	COG3956	TIGRFAM MazG family protein
AC807_RS07140	COG2244	polysaccharide biosynthetic process
AC807_RS07185	COG0251	oxidation-reduction process
AC807_RS07190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AC807_RS07200	COG4466	Protein conserved in bacteria
AC807_RS07210	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AC807_RS07215	COG0084	hydrolase, TatD family'
AC807_RS07230	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AC807_RS07240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AC807_RS07250	COG1774	PSP1 C-terminal conserved region
AC807_RS07255	COG0470	DNA polymerase III
AC807_RS07265	COG3870	Protein conserved in bacteria
AC807_RS07275	COG1982	Orn Lys Arg decarboxylase major
AC807_RS07310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AC807_RS07325	COG2188	Transcriptional regulator
AC807_RS07330	COG0366	Alpha amylase catalytic
AC807_RS07335	COG1263	PTS System
AC807_RS07335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC807_RS07345	COG0493	'glutamate synthase
AC807_RS07350	COG0067	glutamate synthase
AC807_RS07350	COG0069	glutamate synthase activity
AC807_RS07350	COG0070	glutamate synthase
AC807_RS07355	COG0583	DNA-binding transcription factor activity
AC807_RS07390	COG1464	Belongs to the NlpA lipoprotein family
AC807_RS07395	COG2011	ABC-type metal ion transport system permease component
AC807_RS07405	COG0626	cystathionine gamma-synthase activity
AC807_RS07410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AC807_RS07415	COG0733	neurotransmitter:sodium symporter activity
AC807_RS07425	COG1647	Serine aminopeptidase, S33
AC807_RS07440	COG5609	conserved protein (DUF2294)
AC807_RS07450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AC807_RS07460	COG0523	cobalamin synthesis protein
AC807_RS07615	COG3759	membrane
AC807_RS07650	COG2233	PERMEase
AC807_RS07680	COG1823	symporter activity
AC807_RS07695	COG3634	alkyl hydroperoxide reductase activity
AC807_RS07755	COG4974	Belongs to the 'phage' integrase family
AC807_RS07785	COG0012	GTP binding
AC807_RS07790	COG4481	Protein conserved in bacteria
AC807_RS07795	COG0668	transmembrane transport
AC807_RS07800	COG1475	DNA binding
AC807_RS07805	COG0626	cystathionine gamma-synthase activity
AC807_RS07810	COG0626	cystathionine gamma-synthase activity
AC807_RS07815	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AC807_RS07815	COG0646	methionine synthase
AC807_RS07850	COG1131	(ABC) transporter
AC807_RS07860	COG1476	TRANSCRIPTIONal
AC807_RS07870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AC807_RS07875	COG0805	protein transport
AC807_RS07880	COG0672	)-iron permease
AC807_RS07895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AC807_RS07910	COG0431	NADPH-dependent FMN reductase
AC807_RS07915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AC807_RS07920	COG0346	lactoylglutathione lyase activity
AC807_RS07925	COG2271	Major facilitator Superfamily
AC807_RS07945	COG3711	transcriptional antiterminator
AC807_RS07950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC807_RS07960	COG3037	sugar-specific permease SgaT UlaA
AC807_RS07990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AC807_RS08015	COG3314	Sporulation integral membrane protein YlbJ
AC807_RS08040	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AC807_RS08045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AC807_RS08080	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AC807_RS08085	COG1114	Component of the transport system for branched-chain amino acids
AC807_RS08220	COG3942	CHAP domain
AC807_RS08220	COG1388	LysM domain
AC807_RS08250	COG1131	(ABC) transporter
AC807_RS08310	COG2226	methyltransferase
AC807_RS08320	COG2723	6-phospho-beta-galactosidase activity
AC807_RS08325	COG1263	PTS System
AC807_RS08325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC807_RS08325	COG2190	(PTS) system
AC807_RS08330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AC807_RS08365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AC807_RS08370	COG1063	alcohol dehydrogenase
AC807_RS08380	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AC807_RS08385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AC807_RS08390	COG1063	alcohol dehydrogenase
AC807_RS08400	COG1063	alcohol dehydrogenase
AC807_RS08410	COG1063	alcohol dehydrogenase
AC807_RS08415	COG3775	system Galactitol-specific IIC component
AC807_RS08420	COG3414	Phosphotransferase system galactitol-specific IIB component
AC807_RS08440	COG1957	nucleoside hydrolase
AC807_RS08445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC807_RS08445	COG1263	PTS System
AC807_RS08445	COG2190	(PTS) system
AC807_RS08475	COG3189	MarR family transcriptional regulator
AC807_RS08480	COG0747	negative chemotaxis
AC807_RS08495	COG0318	PFAM AMP-dependent synthetase and ligase
AC807_RS08500	COG1960	acyl-CoA dehydrogenase activity
AC807_RS08510	COG0183	Belongs to the thiolase family
AC807_RS08575	COG1755	Isoprenylcysteine carboxyl methyltransferase
AC807_RS08585	COG0673	inositol 2-dehydrogenase activity
AC807_RS08590	COG0673	inositol 2-dehydrogenase activity
AC807_RS08595	COG3833	ABC-type maltose transport systems, permease component
AC807_RS08600	COG1175	transmembrane transport
AC807_RS08610	COG3842	ATPase activity
AC807_RS08630	COG0405	Gamma-glutamyltransferase
AC807_RS08640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC807_RS08645	COG0601	transmembrane transport
AC807_RS08680	COG1737	Transcriptional regulator
AC807_RS08710	COG3961	Belongs to the TPP enzyme family
AC807_RS08715	COG1335	isochorismatase
AC807_RS08720	COG1114	Component of the transport system for branched-chain amino acids
AC807_RS08770	COG5609	conserved protein (DUF2294)
AC807_RS08775	COG1960	acyl-CoA dehydrogenase activity
AC807_RS08780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AC807_RS08815	COG2832	Protein of unknown function (DUF454)
AC807_RS08825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AC807_RS08830	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AC807_RS08840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AC807_RS08870	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AC807_RS08880	COG1086	Polysaccharide biosynthesis protein
AC807_RS08905	COG1454	alcohol dehydrogenase
AC807_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
AC807_RS08935	COG0737	Belongs to the 5'-nucleotidase family
AC807_RS08955	COG3639	organic phosphonate transmembrane transporter activity
AC807_RS08975	COG2814	Major facilitator Superfamily
AC807_RS08980	COG0813	purine-nucleoside phosphorylase activity
AC807_RS09015	COG0438	transferase activity, transferring glycosyl groups
AC807_RS09020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AC807_RS09025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AC807_RS09055	COG1475	DNA binding
AC807_RS09060	COG0019	diaminopimelate decarboxylase activity
AC807_RS09070	COG4264	IucA IucC family
AC807_RS09075	COG4264	IucA IucC family
AC807_RS09080	COG2814	Major facilitator Superfamily
AC807_RS09085	COG4264	IucA IucC family
AC807_RS09090	COG2423	ornithine cyclodeaminase activity
AC807_RS09100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AC807_RS09105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC807_RS09110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC807_RS09125	COG1620	l-lactate permease
AC807_RS09140	COG0697	spore germination
AC807_RS09145	COG4716	Myosin-crossreactive antigen
AC807_RS09150	COG1283	sodium-dependent phosphate transmembrane transporter activity
AC807_RS09160	COG1473	amidohydrolase
AC807_RS09195	COG0823	Involved in the tonB-independent uptake of proteins
AC807_RS09215	COG0583	DNA-binding transcription factor activity
AC807_RS09230	COG0655	NAD(P)H dehydrogenase (quinone) activity
AC807_RS09265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC807_RS09270	COG2210	Belongs to the sulfur carrier protein TusA family
AC807_RS09275	COG1937	Protein conserved in bacteria
AC807_RS09280	COG0730	response to heat
AC807_RS09310	COG1388	LysM domain
AC807_RS09320	COG1124	(ABC) transporter
AC807_RS09325	COG4172	Belongs to the ABC transporter superfamily
AC807_RS09330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC807_RS09380	COG2235	arginine
AC807_RS09390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AC807_RS09395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AC807_RS09405	COG2801	Transposase and inactivated derivatives
AC807_RS09435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AC807_RS09440	COG2801	Transposase and inactivated derivatives
AC807_RS09475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AC807_RS09480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AC807_RS09550	COG2030	dehydratase
AC807_RS09555	COG0584	glycerophosphoryl diester phosphodiesterase
AC807_RS09580	COG0737	Belongs to the 5'-nucleotidase family
AC807_RS09585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AC807_RS09595	COG4863	YycH protein
AC807_RS09625	COG0305	Participates in initiation and elongation during chromosome replication
AC807_RS09635	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AC807_RS09645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AC807_RS09670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AC807_RS09690	COG2501	S4 domain
AC807_RS09730	COG1475	DNA binding
AC807_RS09750	COG1278	Cold shock
AC807_RS09775	COG0577	efflux transmembrane transporter activity
AC807_RS09780	COG1136	(ABC) transporter
AC807_RS09795	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AC807_RS09805	COG2962	Rard protein
AC807_RS09810	COG0471	metal ion transport
AC807_RS09895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AC807_RS09930	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AC807_RS09985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AC807_RS10005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AC807_RS10025	COG1073	alpha beta
AC807_RS10040	COG0438	transferase activity, transferring glycosyl groups
AC807_RS10055	COG1535	isochorismatase
AC807_RS10055	COG3433	isochorismatase activity
AC807_RS10060	COG3942	CHAP domain
AC807_RS10060	COG1705	Flagellar rod assembly protein muramidase FlgJ
AC807_RS10070	COG1482	cell wall glycoprotein biosynthetic process
AC807_RS10075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC807_RS10075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC807_RS10075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AC807_RS10080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AC807_RS10080	COG3711	transcriptional antiterminator
AC807_RS10100	COG1438	arginine binding
AC807_RS10145	COG1846	Transcriptional regulator
AC807_RS10150	COG1785	Belongs to the alkaline phosphatase family
AC807_RS10165	COG0745	RESPONSE REGULATOR receiver
AC807_RS10170	COG2205	protein histidine kinase activity
AC807_RS10175	COG1136	(ABC) transporter
AC807_RS10200	COG0386	Belongs to the glutathione peroxidase family
AC807_RS10210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AC807_RS10225	COG2851	Citrate transporter
AC807_RS10250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC807_RS10260	COG1510	regulation of RNA biosynthetic process
AC807_RS10270	COG1012	belongs to the aldehyde dehydrogenase family
AC807_RS10290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AC807_RS10320	COG0531	amino acid
AC807_RS10335	COG3527	Alpha-acetolactate decarboxylase
AC807_RS10340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AC807_RS10390	COG0167	dihydroorotate dehydrogenase activity
AC807_RS10395	COG3001	Fructosamine kinase
AC807_RS10500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AC807_RS10500	COG2755	lipolytic protein G-D-S-L family
AC807_RS10505	COG3942	CHAP domain
AC807_RS10535	COG0436	Aminotransferase
AC807_RS10580	COG2409	Drug exporters of the RND superfamily
AC807_RS10600	COG0542	response to heat
AC807_RS10605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AC807_RS10610	COG3425	synthase
AC807_RS10635	COG3942	CHAP domain
AC807_RS10645	COG0583	DNA-binding transcription factor activity
AC807_RS10660	COG0028	Belongs to the TPP enzyme family
AC807_RS10680	COG0657	acetylesterase activity
AC807_RS10685	COG0697	spore germination
AC807_RS10700	COG1760	l-serine dehydratase
AC807_RS10705	COG1760	l-serine dehydratase
AC807_RS10725	COG3764	Sortase (surface protein transpeptidase)
AC807_RS10735	COG1131	(ABC) transporter
AC807_RS10740	COG0561	phosphatase activity
AC807_RS10755	COG2514	catechol 2,3-dioxygenase activity
AC807_RS10765	COG1846	Transcriptional regulator
AC807_RS10770	COG0346	lactoylglutathione lyase activity
AC807_RS10775	COG0400	carboxylic ester hydrolase activity
AC807_RS10780	COG3949	Membrane
AC807_RS10800	COG1131	(ABC) transporter
AC807_RS10805	COG1846	Transcriptional regulator
AC807_RS10810	COG2814	Major facilitator Superfamily
AC807_RS10820	COG0586	Pfam SNARE associated Golgi protein
AC807_RS10825	COG2271	Major facilitator Superfamily
AC807_RS10835	COG4876	unkown
AC807_RS10840	COG2357	RelA SpoT domain protein
AC807_RS10845	COG0789	Transcriptional regulator
AC807_RS10850	COG1802	Transcriptional regulator
AC807_RS10855	COG1070	Carbohydrate kinase
AC807_RS10885	COG1846	Transcriptional regulator
AC807_RS10890	COG1846	Transcriptional regulator
AC807_RS10895	COG3583	domain protein
AC807_RS10930	COG0494	nUDIX hydrolase
AC807_RS11015	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AC807_RS11020	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AC807_RS11050	COG0747	negative chemotaxis
AC807_RS11055	COG0601	transmembrane transport
AC807_RS11060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AC807_RS11065	COG0444	Belongs to the ABC transporter superfamily
AC807_RS11070	COG1124	(ABC) transporter
AC807_RS11085	COG0069	glutamate synthase activity
AC807_RS11090	COG4808	Protein conserved in bacteria
AC807_RS11110	COG1363	Peptidase, m42
AC807_RS11115	COG4619	ABC transporter
AC807_RS11120	COG0390	transport system, permease component
AC807_RS11125	COG2814	Major facilitator Superfamily
AC807_RS11130	COG2272	Belongs to the type-B carboxylesterase lipase family
AC807_RS11135	COG0531	amino acid
AC807_RS11140	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AC807_RS11160	COG1174	glycine betaine transport
AC807_RS11170	COG1174	glycine betaine transport
AC807_RS11180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AC807_RS11205	COG0531	amino acid
AC807_RS11220	COG1113	amino acid transport
AC807_RS11240	COG2814	Major facilitator Superfamily
AC807_RS11250	COG1929	Belongs to the glycerate kinase type-1 family
AC807_RS11270	COG1132	(ABC) transporter
AC807_RS11270	COG2375	cellular response to nickel ion
AC807_RS11275	COG1132	(ABC) transporter
AC807_RS11290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AC807_RS11295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AC807_RS11305	COG0156	8-amino-7-oxononanoate synthase activity
AC807_RS11350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AC807_RS11370	COG2814	Major facilitator Superfamily
AC807_RS11375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AC807_RS11380	COG0765	amino acid transport
AC807_RS11385	COG1126	abc transporter atp-binding protein
AC807_RS11420	COG0803	Belongs to the bacterial solute-binding protein 9 family
AC807_RS11420	COG3443	Belongs to the bacterial solute-binding protein 9 family
AC807_RS11435	COG2116	formate transmembrane transporter activity
AC807_RS11440	COG0454	-acetyltransferase
AC807_RS11455	COG2146	nitrite reductase [NAD(P)H] activity
AC807_RS11465	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AC807_RS11470	COG1140	nitrate reductase beta subunit
AC807_RS11480	COG2181	nitrate reductase activity
AC807_RS11500	COG0789	Transcriptional regulator
AC807_RS11540	COG3871	stress protein (general stress protein 26)
AC807_RS11555	COG1263	PTS System
AC807_RS11555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC807_RS11570	COG1511	domain protein
AC807_RS11595	COG0456	acetyltransferase
AC807_RS11600	COG0604	alcohol dehydrogenase
AC807_RS11620	COG1620	l-lactate permease
AC807_RS11690	COG2814	Major facilitator Superfamily
AC807_RS11700	COG1566	PFAM secretion protein HlyD family protein
AC807_RS11705	COG2814	Major facilitator Superfamily
AC807_RS11715	COG0657	acetylesterase activity
AC807_RS11730	COG0598	Magnesium transport protein CorA
AC807_RS11740	COG0786	glutamate:sodium symporter activity
AC807_RS11750	COG3152	Membrane
AC807_RS11755	COG4152	abc transporter atp-binding protein
AC807_RS11760	COG1668	transmembrane transport
AC807_RS11780	COG2258	MOSC domain
AC807_RS11805	COG0583	DNA-binding transcription factor activity
AC807_RS11820	COG1473	amidohydrolase
AC807_RS11825	COG1028	Short-chain dehydrogenase reductase Sdr
AC807_RS11845	COG1737	Transcriptional regulator
AC807_RS11850	COG1263	PTS System
AC807_RS11850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AC807_RS11860	COG0385	Bile acid
AC807_RS11865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AC807_RS11885	COG1113	amino acid transport
AC807_RS11960	COG3942	CHAP domain
AC807_RS11975	COG1757	Na H antiporter
AC807_RS11985	COG3942	CHAP domain
AC807_RS12050	COG4413	Urea transporter
AC807_RS12055	COG1960	acyl-CoA dehydrogenase activity
AC807_RS12070	COG1268	BioY protein
AC807_RS12085	COG0725	ABC transporter, periplasmic molybdate-binding protein
AC807_RS12090	COG4149	molybdate abc transporter
AC807_RS12095	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AC807_RS12100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AC807_RS12120	COG1763	Mo-molybdopterin cofactor biosynthetic process
AC807_RS12190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AC807_RS12235	COG2252	PERMEase
AC807_RS12350	COG0201	protein transport
AC807_RS12440	COG0542	response to heat
AC807_RS12460	COG0028	Belongs to the TPP enzyme family
AC807_RS12465	COG3527	Alpha-acetolactate decarboxylase
AC807_RS12485	COG5492	domain, Protein
AC807_RS12495	COG0789	Transcriptional regulator
AC807_RS12500	COG0656	L-ascorbic acid biosynthetic process
AC807_RS12520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AC807_RS12570	COG2130	NADP-dependent
AC807_RS12580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AC807_RS12620	COG2814	Major facilitator Superfamily
AC807_RS12625	COG4264	IucA IucC family
AC807_RS12630	COG3457	Alanine racemase
AC807_RS12640	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AC807_RS12645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC807_RS12650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AC807_RS12655	COG3314	Sporulation integral membrane protein YlbJ
AC807_RS12665	COG1988	membrane-bound metal-dependent
AC807_RS12675	COG1272	protein, Hemolysin III
AC807_RS12690	COG2814	Major facilitator Superfamily
AC807_RS12695	COG0489	protein tyrosine kinase activity
AC807_RS12760	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AC807_RS12790	COG3711	transcriptional antiterminator
AC807_RS12805	COG1119	ATPase activity
AC807_RS12810	COG0561	phosphatase activity
AC807_RS12845	COG0640	Transcriptional regulator
AC807_RS12850	COG0702	epimerase
AC807_RS12855	COG1482	cell wall glycoprotein biosynthetic process
AC807_RS12875	COG0783	Belongs to the Dps family
AC807_RS12880	COG0813	purine-nucleoside phosphorylase activity
AC807_RS12935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AC807_RS12975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AC807_RS12995	COG2890	protein-(glutamine-N5) methyltransferase activity
AC807_RS13000	COG0009	L-threonylcarbamoyladenylate synthase
AC807_RS13025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AC807_RS13100	COG0629	single-stranded DNA binding
AC807_RS13150	COG1418	mRNA catabolic process
AC807_RS13160	COG1937	Protein conserved in bacteria
AC807_RS13175	COG0772	Belongs to the SEDS family
AC807_RS13185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AC807_RS13195	COG0745	RESPONSE REGULATOR receiver
AC807_RS13200	COG2205	protein histidine kinase activity
AC807_RS13230	COG3428	Bacterial PH domain
AC807_RS13265	COG2208	phosphoserine phosphatase activity
AC807_RS13270	COG1366	Belongs to the anti-sigma-factor antagonist family
AC807_RS13280	COG1191	sigma factor activity
AC807_RS13285	COG2183	response to ionizing radiation
AC807_RS13360	COG0028	Belongs to the TPP enzyme family
AC807_RS13375	COG0802	atpase or kinase
AC807_RS13380	COG1214	PFAM Peptidase M22, glycoprotease
AC807_RS13385	COG0456	acetyltransferase
AC807_RS13395	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AC807_RS13405	COG0488	(ABC) transporter
AC807_RS13415	COG2391	methyltransferase activity
AC807_RS13420	COG0425	Belongs to the sulfur carrier protein TusA family
AC807_RS13425	COG0004	ammonium transporteR
AC807_RS13430	COG1609	Transcriptional regulator
AC807_RS13435	COG1621	beta-fructofuranosidase activity
AC807_RS13440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AC807_RS13515	COG5484	DNA packaging
AC807_RS13515	COG3728	DNA packaging
AC807_RS13530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AC807_RS13535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AC807_RS13540	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AC807_RS13590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AC807_RS13760	COG0740	serine-type endopeptidase activity
AC807_RS13805	COG0739	heme binding
AC807_RS13845	COG5632	N-Acetylmuramoyl-L-alanine amidase
AC807_RS13845	COG1388	LysM domain
AC807_RS13855	COG0860	N-Acetylmuramoyl-L-alanine amidase
AC807_RS13855	COG1388	LysM domain
AC807_RS13915	COG1725	Transcriptional regulator
AC807_RS13930	COG1131	(ABC) transporter
AC807_RS13980	COG1012	belongs to the aldehyde dehydrogenase family
AC807_RS13995	COG1335	isochorismatase
AC807_RS14015	COG0077	Prephenate dehydratase
AC807_RS14025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AC807_RS14060	COG4496	protein, YerC YecD
AC807_RS14070	COG0210	DNA helicase
AC807_RS14080	COG4851	CamS sex pheromone cAM373 precursor
AC807_RS14195	COG2197	response regulator
AC807_RS14200	COG1295	ribonuclease BN
AC807_RS14220	COG2309	aminopeptidase activity
AC807_RS14225	COG1607	acyl-coa hydrolase
AC807_RS14230	COG0535	radical SAM domain protein
AC807_RS14235	COG4974	Belongs to the 'phage' integrase family
AC807_RS14330	COG1484	DNA-dependent DNA replication
AC807_RS14550	COG5632	N-Acetylmuramoyl-L-alanine amidase
AC807_RS14550	COG1388	LysM domain
AC807_RS14600	COG1134	teichoic acid transport
AC807_RS14600	COG1388	LysM domain
AC807_RS14615	COG1988	membrane-bound metal-dependent
AC807_RS14640	COG4129	membrane
AC807_RS14650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AC807_RS14655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AC807_RS14825	COG0765	amino acid transport
AC807_RS14830	COG1126	abc transporter atp-binding protein
AC807_RS14835	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AC807_RS14870	COG0564	pseudouridine synthase activity
AC807_RS14875	COG4585	Histidine kinase
AC807_RS14875	COG2203	Gaf domain
AC807_RS14880	COG2197	response regulator
AC807_RS14905	COG0420	3'-5' exonuclease activity
AC807_RS14935	COG0537	adenosine 5'-monophosphoramidase activity
AC807_RS14940	COG1131	(ABC) transporter
AC807_RS14970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AC807_RS15075	COG1131	(ABC) transporter