locus-tag	class	description
SAVC_RS00015	COG2501	S4 domain
SAVC_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SAVC_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SAVC_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
SAVC_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SAVC_RS00075	COG0359	binds to the 23S rRNA
SAVC_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
SAVC_RS00110	COG4863	YycH protein
SAVC_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SAVC_RS00125	COG0737	Belongs to the 5'-nucleotidase family
SAVC_RS00160	COG0730	response to heat
SAVC_RS00165	COG1937	Protein conserved in bacteria
SAVC_RS00170	COG2210	Belongs to the sulfur carrier protein TusA family
SAVC_RS00175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAVC_RS00215	COG0655	NAD(P)H dehydrogenase (quinone) activity
SAVC_RS00230	COG0583	DNA-binding transcription factor activity
SAVC_RS00250	COG0823	Involved in the tonB-independent uptake of proteins
SAVC_RS00280	COG1473	amidohydrolase
SAVC_RS00290	COG1283	sodium-dependent phosphate transmembrane transporter activity
SAVC_RS00295	COG4716	Myosin-crossreactive antigen
SAVC_RS00300	COG0697	spore germination
SAVC_RS00315	COG1620	l-lactate permease
SAVC_RS00320	COG1388	LysM domain
SAVC_RS00330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAVC_RS00335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAVC_RS00340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAVC_RS00350	COG2423	ornithine cyclodeaminase activity
SAVC_RS00355	COG4264	IucA IucC family
SAVC_RS00360	COG2814	Major facilitator Superfamily
SAVC_RS00365	COG4264	IucA IucC family
SAVC_RS00370	COG4264	IucA IucC family
SAVC_RS00380	COG0019	diaminopimelate decarboxylase activity
SAVC_RS00385	COG1475	DNA binding
SAVC_RS00415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAVC_RS00420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAVC_RS00425	COG0438	transferase activity, transferring glycosyl groups
SAVC_RS00460	COG0813	purine-nucleoside phosphorylase activity
SAVC_RS00465	COG2814	Major facilitator Superfamily
SAVC_RS00485	COG3639	organic phosphonate transmembrane transporter activity
SAVC_RS00505	COG0737	Belongs to the 5'-nucleotidase family
SAVC_RS00535	COG1454	alcohol dehydrogenase
SAVC_RS00535	COG1012	belongs to the aldehyde dehydrogenase family
SAVC_RS00560	COG1086	Polysaccharide biosynthesis protein
SAVC_RS00570	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAVC_RS00600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SAVC_RS00610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SAVC_RS00615	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAVC_RS00625	COG2832	Protein of unknown function (DUF454)
SAVC_RS00660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SAVC_RS00665	COG1960	acyl-CoA dehydrogenase activity
SAVC_RS00670	COG5609	conserved protein (DUF2294)
SAVC_RS00720	COG1114	Component of the transport system for branched-chain amino acids
SAVC_RS00725	COG1335	isochorismatase
SAVC_RS00730	COG3961	Belongs to the TPP enzyme family
SAVC_RS00760	COG1737	Transcriptional regulator
SAVC_RS00795	COG0601	transmembrane transport
SAVC_RS00800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAVC_RS00810	COG0405	Gamma-glutamyltransferase
SAVC_RS00830	COG3842	ATPase activity
SAVC_RS00840	COG1175	transmembrane transport
SAVC_RS00845	COG3833	ABC-type maltose transport systems, permease component
SAVC_RS00850	COG0673	inositol 2-dehydrogenase activity
SAVC_RS00855	COG0673	inositol 2-dehydrogenase activity
SAVC_RS00865	COG1755	Isoprenylcysteine carboxyl methyltransferase
SAVC_RS00930	COG0183	Belongs to the thiolase family
SAVC_RS00940	COG1960	acyl-CoA dehydrogenase activity
SAVC_RS00945	COG0318	PFAM AMP-dependent synthetase and ligase
SAVC_RS00960	COG0747	negative chemotaxis
SAVC_RS00965	COG3189	MarR family transcriptional regulator
SAVC_RS00995	COG1263	PTS System
SAVC_RS00995	COG2190	(PTS) system
SAVC_RS00995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAVC_RS01000	COG1957	nucleoside hydrolase
SAVC_RS01020	COG3414	Phosphotransferase system galactitol-specific IIB component
SAVC_RS01025	COG3775	system Galactitol-specific IIC component
SAVC_RS01030	COG1063	alcohol dehydrogenase
SAVC_RS01040	COG1063	alcohol dehydrogenase
SAVC_RS01050	COG1063	alcohol dehydrogenase
SAVC_RS01055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAVC_RS01060	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAVC_RS01070	COG1063	alcohol dehydrogenase
SAVC_RS01075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAVC_RS01110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAVC_RS01115	COG1263	PTS System
SAVC_RS01115	COG2190	(PTS) system
SAVC_RS01115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAVC_RS01120	COG2723	6-phospho-beta-galactosidase activity
SAVC_RS01130	COG2226	methyltransferase
SAVC_RS01190	COG1131	(ABC) transporter
SAVC_RS01220	COG3942	CHAP domain
SAVC_RS01220	COG1388	LysM domain
SAVC_RS01340	COG1114	Component of the transport system for branched-chain amino acids
SAVC_RS01345	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
SAVC_RS01355	COG0577	efflux transmembrane transporter activity
SAVC_RS01380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAVC_RS01385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SAVC_RS01410	COG3314	Sporulation integral membrane protein YlbJ
SAVC_RS01435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAVC_RS01460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SAVC_RS01465	COG3037	sugar-specific permease SgaT UlaA
SAVC_RS01475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAVC_RS01480	COG3711	transcriptional antiterminator
SAVC_RS01500	COG2271	Major facilitator Superfamily
SAVC_RS01505	COG0346	lactoylglutathione lyase activity
SAVC_RS01510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAVC_RS01515	COG0431	NADPH-dependent FMN reductase
SAVC_RS01530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAVC_RS01535	COG2822	iron ion transport
SAVC_RS01545	COG0672	)-iron permease
SAVC_RS01550	COG0805	protein transport
SAVC_RS01555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SAVC_RS01565	COG1476	TRANSCRIPTIONal
SAVC_RS01575	COG1131	(ABC) transporter
SAVC_RS01610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SAVC_RS01610	COG0646	methionine synthase
SAVC_RS01615	COG0626	cystathionine gamma-synthase activity
SAVC_RS01620	COG0626	cystathionine gamma-synthase activity
SAVC_RS01625	COG1475	DNA binding
SAVC_RS01630	COG0668	transmembrane transport
SAVC_RS01635	COG4481	Protein conserved in bacteria
SAVC_RS01640	COG0012	GTP binding
SAVC_RS01670	COG4974	Belongs to the 'phage' integrase family
SAVC_RS01730	COG3634	alkyl hydroperoxide reductase activity
SAVC_RS01745	COG1823	symporter activity
SAVC_RS01775	COG2233	PERMEase
SAVC_RS01810	COG3759	membrane
SAVC_RS01945	COG0523	cobalamin synthesis protein
SAVC_RS01955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SAVC_RS01965	COG5609	conserved protein (DUF2294)
SAVC_RS01980	COG1647	Serine aminopeptidase, S33
SAVC_RS01990	COG0733	neurotransmitter:sodium symporter activity
SAVC_RS01995	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SAVC_RS02000	COG0626	cystathionine gamma-synthase activity
SAVC_RS02010	COG2011	ABC-type metal ion transport system permease component
SAVC_RS02015	COG1464	Belongs to the NlpA lipoprotein family
SAVC_RS02050	COG0583	DNA-binding transcription factor activity
SAVC_RS02055	COG0070	glutamate synthase
SAVC_RS02055	COG0067	glutamate synthase
SAVC_RS02055	COG0069	glutamate synthase activity
SAVC_RS02060	COG0493	'glutamate synthase
SAVC_RS02070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAVC_RS02070	COG1263	PTS System
SAVC_RS02075	COG0366	Alpha amylase catalytic
SAVC_RS02080	COG2188	Transcriptional regulator
SAVC_RS02095	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SAVC_RS02130	COG1982	Orn Lys Arg decarboxylase major
SAVC_RS02140	COG3870	Protein conserved in bacteria
SAVC_RS02150	COG0470	DNA polymerase III
SAVC_RS02155	COG1774	PSP1 C-terminal conserved region
SAVC_RS02165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SAVC_RS02175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SAVC_RS02190	COG0084	hydrolase, TatD family'
SAVC_RS02195	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAVC_RS02205	COG4466	Protein conserved in bacteria
SAVC_RS02215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SAVC_RS02220	COG0251	oxidation-reduction process
SAVC_RS02235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SAVC_RS02265	COG2244	polysaccharide biosynthetic process
SAVC_RS02270	COG3956	TIGRFAM MazG family protein
SAVC_RS02275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SAVC_RS02285	COG1098	S1 RNA binding domain
SAVC_RS02300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SAVC_RS02325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SAVC_RS02400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SAVC_RS02415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAVC_RS02425	COG3880	PFAM UvrB UvrC protein
SAVC_RS02445	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SAVC_RS02450	COG4956	integral membrane protein (PIN domain superfamily)
SAVC_RS02470	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SAVC_RS02520	COG2813	Specifically methylates the guanine in position
SAVC_RS02560	COG1473	amidohydrolase
SAVC_RS02590	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SAVC_RS02595	COG1428	Deoxynucleoside kinase
SAVC_RS02600	COG1428	Deoxynucleoside kinase
SAVC_RS02610	COG0561	phosphatase activity
SAVC_RS02625	COG4932	domain protein
SAVC_RS02645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SAVC_RS02660	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SAVC_RS02750	COG0095	Lipoate-protein ligase
SAVC_RS02755	COG0083	homoserine kinase activity
SAVC_RS02775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAVC_RS02860	COG0667	Aldo Keto reductase
SAVC_RS02865	COG0655	NAD(P)H dehydrogenase (quinone) activity
SAVC_RS02875	COG1078	dGTPase activity
SAVC_RS02910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAVC_RS02915	COG4139	cobalamin transport
SAVC_RS02965	COG4974	Belongs to the 'phage' integrase family
SAVC_RS03010	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAVC_RS03015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAVC_RS03020	COG1121	(ABC) transporter
SAVC_RS03025	COG1321	iron dependent repressor
SAVC_RS03035	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SAVC_RS03045	COG1682	transport, permease protein
SAVC_RS03050	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SAVC_RS03055	COG1216	Glycosyl transferase, family 2
SAVC_RS03060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SAVC_RS03065	COG1686	Belongs to the peptidase S11 family
SAVC_RS03070	COG1132	(ABC) transporter
SAVC_RS03075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SAVC_RS03085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SAVC_RS03090	COG1120	ATPase activity
SAVC_RS03095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAVC_RS03100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAVC_RS03105	COG2376	Dihydroxyacetone kinase
SAVC_RS03115	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SAVC_RS03125	COG3949	Membrane
SAVC_RS03150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SAVC_RS03165	COG1136	(ABC) transporter
SAVC_RS03170	COG0577	efflux transmembrane transporter activity
SAVC_RS03175	COG1392	Phosphate transport regulator
SAVC_RS03180	COG0306	phosphate transporter
SAVC_RS03185	COG3942	CHAP domain
SAVC_RS03185	COG1388	LysM domain
SAVC_RS03195	COG1917	Cupin 2, conserved barrel domain protein
SAVC_RS03195	COG4977	sequence-specific DNA binding
SAVC_RS03225	COG0583	DNA-binding transcription factor activity
SAVC_RS03235	COG2814	Major facilitator Superfamily
SAVC_RS03240	COG2839	Protein conserved in bacteria
SAVC_RS03270	COG1611	Belongs to the LOG family
SAVC_RS03290	COG4988	ABC transporter
SAVC_RS03295	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SAVC_RS03305	COG0523	cobalamin synthesis protein
SAVC_RS03310	COG4989	oxidoreductase activity
SAVC_RS03320	COG0471	metal ion transport
SAVC_RS03325	COG0415	Belongs to the DNA photolyase family
SAVC_RS03355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SAVC_RS03360	COG1349	DNA-binding transcription factor activity
SAVC_RS03365	COG1105	Belongs to the carbohydrate kinase PfkB family
SAVC_RS03370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAVC_RS03370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAVC_RS03370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAVC_RS03380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SAVC_RS03385	COG1253	flavin adenine dinucleotide binding
SAVC_RS03390	COG0656	L-ascorbic acid biosynthetic process
SAVC_RS03395	COG0463	Glycosyl transferase, family 2
SAVC_RS03430	COG0720	synthase
SAVC_RS03440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SAVC_RS03440	COG0512	Glutamine amidotransferase of anthranilate synthase
SAVC_RS03445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAVC_RS03480	COG0488	(ABC) transporter
SAVC_RS03485	COG0514	ATP-dependent DNA helicase (RecQ)
SAVC_RS03490	COG0517	IMP dehydrogenase activity
SAVC_RS03490	COG1125	glycine betaine transport
SAVC_RS03495	COG1174	glycine betaine transport
SAVC_RS03525	COG3104	oligopeptide transport
SAVC_RS03545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAVC_RS03550	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SAVC_RS03565	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAVC_RS03570	COG4605	iron ion homeostasis
SAVC_RS03575	COG4604	ABC transporter, ATP-binding protein
SAVC_RS03580	COG4607	ABC-type enterochelin transport system periplasmic component
SAVC_RS03635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SAVC_RS03640	COG1739	Uncharacterized protein family UPF0029
SAVC_RS03650	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SAVC_RS03655	COG1040	competence protein
SAVC_RS03685	COG3942	CHAP domain
SAVC_RS03685	COG1388	LysM domain
SAVC_RS03745	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SAVC_RS03790	COG0149	triose-phosphate isomerase activity
SAVC_RS03810	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SAVC_RS03815	COG1647	Serine aminopeptidase, S33
SAVC_RS03820	COG0557	exoribonuclease II activity
SAVC_RS03865	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
SAVC_RS03865	COG3266	domain, Protein
SAVC_RS03890	COG1278	Cold shock
SAVC_RS03930	COG0406	alpha-ribazole phosphatase activity
SAVC_RS03935	COG1279	arginine transmembrane transporter activity
SAVC_RS03960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAVC_RS03965	COG1393	Belongs to the ArsC family
SAVC_RS03980	COG3878	Protein conserved in bacteria
SAVC_RS03990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SAVC_RS04005	COG2011	ABC-type metal ion transport system permease component
SAVC_RS04010	COG1464	Belongs to the NlpA lipoprotein family
SAVC_RS04025	COG0396	ATPase activity
SAVC_RS04030	COG0719	Fe-S assembly protein
SAVC_RS04040	COG0822	iron-sulfur transferase activity
SAVC_RS04060	COG1253	flavin adenine dinucleotide binding
SAVC_RS04075	COG1801	Protein of unknown function DUF72
SAVC_RS04080	COG0730	response to heat
SAVC_RS04095	COG4470	Protein conserved in bacteria
SAVC_RS04105	COG2445	Protein of unknown function DUF86
SAVC_RS04135	COG1696	Membrane protein involved in D-alanine export
SAVC_RS04145	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SAVC_RS04150	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SAVC_RS04155	COG4837	Protein of unknown function (DUF1462)
SAVC_RS04160	COG1252	NADH dehydrogenase
SAVC_RS04170	COG0316	Belongs to the HesB IscA family
SAVC_RS04180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SAVC_RS04185	COG2056	Na+-H+ antiporter family
SAVC_RS04190	COG2050	protein possibly involved in aromatic compounds catabolism
SAVC_RS04245	COG1098	S1 RNA binding domain
SAVC_RS04250	COG1902	pentaerythritol trinitrate reductase activity
SAVC_RS04270	COG0584	glycerophosphoryl diester phosphodiesterase
SAVC_RS04285	COG0166	Belongs to the GPI family
SAVC_RS04290	COG0398	Pfam SNARE associated Golgi protein
SAVC_RS04330	COG0561	phosphatase activity
SAVC_RS04355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SAVC_RS04370	COG1881	PFAM PEBP family protein
SAVC_RS04400	COG0601	transmembrane transport
SAVC_RS04405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAVC_RS04410	COG0444	Belongs to the ABC transporter superfamily
SAVC_RS04415	COG4608	Belongs to the ABC transporter superfamily
SAVC_RS04420	COG4166	transmembrane transport
SAVC_RS04425	COG0747	negative chemotaxis
SAVC_RS04430	COG0444	Belongs to the ABC transporter superfamily
SAVC_RS04435	COG4608	Belongs to the ABC transporter superfamily
SAVC_RS04440	COG0601	transmembrane transport
SAVC_RS04445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAVC_RS04470	COG1164	Oligoendopeptidase f
SAVC_RS04480	COG2346	COG2346, Truncated hemoglobins
SAVC_RS04495	COG2357	RelA SpoT domain protein
SAVC_RS04505	COG0564	pseudouridine synthase activity
SAVC_RS04510	COG2239	Acts as a magnesium transporter
SAVC_RS04515	COG0569	domain protein
SAVC_RS04515	COG0475	glutathione-regulated potassium exporter activity
SAVC_RS04520	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SAVC_RS04525	COG0628	permease
SAVC_RS04530	COG1115	amino acid carrier protein
SAVC_RS04570	COG0861	Integral membrane protein TerC family
SAVC_RS04575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAVC_RS04580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAVC_RS04585	COG0737	Belongs to the 5'-nucleotidase family
SAVC_RS04600	COG4903	ComK protein
SAVC_RS04615	COG4873	Protein conserved in bacteria
SAVC_RS04670	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAVC_RS04680	COG2314	TM2 domain
SAVC_RS04685	COG0456	acetyltransferase
SAVC_RS04690	COG1575	Belongs to the MenA family. Type 1 subfamily
SAVC_RS04695	COG1169	isochorismate synthase
SAVC_RS04705	COG2267	carboxylic ester hydrolase activity
SAVC_RS04730	COG0436	Aminotransferase
SAVC_RS04735	COG3594	Acyltransferase
SAVC_RS04750	COG5632	N-Acetylmuramoyl-L-alanine amidase
SAVC_RS04750	COG4193	domain, Protein
SAVC_RS04750	COG3266	domain, Protein
SAVC_RS04765	COG1316	TRANSCRIPTIONal
SAVC_RS04770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAVC_RS04810	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SAVC_RS04825	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SAVC_RS04855	COG0138	bifunctional purine biosynthesis protein purh
SAVC_RS04865	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SAVC_RS04870	COG4172	Belongs to the ABC transporter superfamily
SAVC_RS04875	COG4721	ABC-type cobalt transport system, permease component
SAVC_RS04895	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SAVC_RS04920	COG1271	oxidase subunit
SAVC_RS04925	COG1294	oxidase, subunit
SAVC_RS04930	COG0569	domain protein
SAVC_RS05000	COG1176	ABC-type spermidine putrescine transport system, permease component I
SAVC_RS05005	COG1177	transmembrane transport
SAVC_RS05010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
SAVC_RS05035	COG0483	inositol monophosphate 1-phosphatase activity
SAVC_RS05045	COG1217	gtp-binding protein TYPA
SAVC_RS05055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SAVC_RS05065	COG0772	Belongs to the SEDS family
SAVC_RS05100	COG3679	Belongs to the UPF0342 family
SAVC_RS05120	COG0742	ribosomal rna small subunit methyltransferase
SAVC_RS05175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAVC_RS05180	COG4509	Sortase family
SAVC_RS05195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SAVC_RS05215	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
SAVC_RS05225	COG1796	DNA polymerase
SAVC_RS05225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SAVC_RS05250	COG2009	succinate dehydrogenase
SAVC_RS05255	COG1053	succinate dehydrogenase
SAVC_RS05260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SAVC_RS05385	COG1288	antiporter activity
SAVC_RS05420	COG1011	Hydrolase
SAVC_RS05445	COG4839	cell division protein FtsL
SAVC_RS05450	COG0768	penicillin binding
SAVC_RS05465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SAVC_RS05470	COG0849	cell division
SAVC_RS05485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SAVC_RS05495	COG0762	integral membrane protein
SAVC_RS05500	COG2302	S4 RNA-binding domain
SAVC_RS05505	COG3599	regulation of cell shape
SAVC_RS05515	COG2514	catechol 2,3-dioxygenase activity
SAVC_RS05530	COG0564	pseudouridine synthase activity
SAVC_RS05540	COG2233	PERMEase
SAVC_RS05585	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SAVC_RS05600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SAVC_RS05605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SAVC_RS05615	COG2314	TM2 domain
SAVC_RS05630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SAVC_RS05630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SAVC_RS05640	COG0631	protein serine/threonine phosphatase activity
SAVC_RS05655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SAVC_RS05670	COG1302	Protein conserved in bacteria
SAVC_RS05680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SAVC_RS05720	COG1196	nuclear chromosome segregation
SAVC_RS05725	COG0552	protein localization to endoplasmic reticulum
SAVC_RS05735	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SAVC_RS05800	COG0758	DNA mediated transformation
SAVC_RS05895	COG0195	Participates in both transcription termination and antitermination
SAVC_RS05900	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SAVC_RS05925	COG0196	riboflavin kinase activity
SAVC_RS05950	COG2188	Transcriptional regulator
SAVC_RS05955	COG0612	Peptidase, M16
SAVC_RS05960	COG0612	Peptidase, M16
SAVC_RS05965	COG0300	oxidoreductase activity
SAVC_RS05985	COG1058	Belongs to the CinA family
SAVC_RS05985	COG1546	Belongs to the CinA family
SAVC_RS06005	COG1692	metallophosphoesterase
SAVC_RS06010	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
SAVC_RS06010	COG0674	pyruvate-flavodoxin oxidoreductase activity
SAVC_RS06015	COG1013	pyruvate-flavodoxin oxidoreductase activity
SAVC_RS06070	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SAVC_RS06080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SAVC_RS06085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SAVC_RS06110	COG1923	regulation of RNA biosynthetic process
SAVC_RS06120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SAVC_RS06125	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SAVC_RS06130	COG0789	Transcriptional regulator
SAVC_RS06250	COG1131	(ABC) transporter
SAVC_RS06265	COG2197	response regulator
SAVC_RS06275	COG1525	nuclease
SAVC_RS06290	COG0527	aspartate kinase activity
SAVC_RS06295	COG0460	homoserine dehydrogenase
SAVC_RS06300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SAVC_RS06325	COG0833	amino acid
SAVC_RS06355	COG2340	Cysteine-rich secretory protein family
SAVC_RS06390	COG4846	Membrane protein involved in cytochrome C biogenesis
SAVC_RS06410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAVC_RS06420	COG0824	Thioesterase
SAVC_RS06440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SAVC_RS06450	COG1115	amino acid carrier protein
SAVC_RS06465	COG0628	permease
SAVC_RS06470	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SAVC_RS06470	COG0392	lysyltransferase activity
SAVC_RS06490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SAVC_RS06495	COG0287	Prephenate dehydrogenase
SAVC_RS06500	COG1363	Peptidase, m42
SAVC_RS06505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SAVC_RS06510	COG0512	Glutamine amidotransferase of anthranilate synthase
SAVC_RS06550	COG0561	phosphatase activity
SAVC_RS06595	COG0704	Plays a role in the regulation of phosphate uptake
SAVC_RS06605	COG0581	inorganic phosphate transmembrane transporter activity
SAVC_RS06610	COG0573	inorganic phosphate transmembrane transporter activity
SAVC_RS06635	COG0488	(ABC) transporter
SAVC_RS06640	COG0527	aspartate kinase activity
SAVC_RS06645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SAVC_RS06725	COG4548	von Willebrand factor, type A
SAVC_RS06730	COG0714	Associated with various cellular activities
SAVC_RS06775	COG0671	phosphoesterase, PA-phosphatase related
SAVC_RS06840	COG1413	lyase activity
SAVC_RS06855	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SAVC_RS06885	COG0531	amino acid
SAVC_RS06895	COG0686	Belongs to the AlaDH PNT family
SAVC_RS06900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAVC_RS06905	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SAVC_RS06925	COG0116	Belongs to the methyltransferase superfamily
SAVC_RS06955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SAVC_RS06955	COG4499	WXG100 protein secretion system (Wss), protein YukC
SAVC_RS06965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SAVC_RS06970	COG3935	DnaD domain protein
SAVC_RS06995	COG0438	transferase activity, transferring glycosyl groups
SAVC_RS07000	COG1694	Mazg nucleotide pyrophosphohydrolase
SAVC_RS07005	COG2738	Putative neutral zinc metallopeptidase
SAVC_RS07010	COG4347	Protein of unknown function (DUF1405)
SAVC_RS07015	COG5582	Belongs to the UPF0302 family
SAVC_RS07030	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SAVC_RS07050	COG0142	geranyltranstransferase activity
SAVC_RS07115	COG0492	ferredoxin-NADP+ reductase activity
SAVC_RS07130	COG0514	ATP-dependent DNA helicase (RecQ)
SAVC_RS07140	COG1141	Ferredoxin
SAVC_RS07185	COG5002	protein histidine kinase activity
SAVC_RS07190	COG0745	RESPONSE REGULATOR receiver
SAVC_RS07195	COG1187	pseudouridine synthase activity
SAVC_RS07220	COG0735	belongs to the Fur family
SAVC_RS07225	COG0494	nUDIX hydrolase
SAVC_RS07230	COG0667	Aldo Keto reductase
SAVC_RS07240	COG4221	oxidoreductase activity
SAVC_RS07255	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SAVC_RS07265	COG0366	Alpha amylase catalytic
SAVC_RS07270	COG1609	Transcriptional regulator
SAVC_RS07290	COG2195	Cleaves the N-terminal amino acid of tripeptides
SAVC_RS07300	COG4129	membrane
SAVC_RS07310	COG0508	dehydrogenase complex catalyzes the overall conversion of
SAVC_RS07315	COG0022	dehydrogenase e1 component
SAVC_RS07320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SAVC_RS07325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SAVC_RS07330	COG0497	DNA recombination
SAVC_RS07360	COG1302	Protein conserved in bacteria
SAVC_RS07365	COG0439	Biotin carboxylase
SAVC_RS07370	COG0511	ligase activity, forming carbon-carbon bonds
SAVC_RS07380	COG0006	proline dipeptidase activity
SAVC_RS07395	COG0095	Lipoate-protein ligase
SAVC_RS07400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SAVC_RS07445	COG4537	Required for transformation and DNA binding
SAVC_RS07450	COG1459	type II secretion system
SAVC_RS07455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SAVC_RS07460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAVC_RS07465	COG0011	TIGRFAM Protein of
SAVC_RS07470	COG1940	carbohydrate kinase activity
SAVC_RS07475	COG4483	Protein conserved in bacteria
SAVC_RS07485	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SAVC_RS07495	COG0768	penicillin binding
SAVC_RS07510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SAVC_RS07515	COG1121	(ABC) transporter
SAVC_RS07525	COG0513	Belongs to the DEAD box helicase family
SAVC_RS07535	COG2384	SAM-dependent methyltransferase
SAVC_RS07555	COG0517	IMP dehydrogenase activity
SAVC_RS07570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SAVC_RS07575	COG0295	cytidine deaminase activity
SAVC_RS07590	COG1702	phosphate starvation-inducible protein PhoH
SAVC_RS07605	COG1030	water channel activity
SAVC_RS07615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SAVC_RS07620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SAVC_RS07650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SAVC_RS07670	COG1466	dna polymerase III delta subunit
SAVC_RS07675	COG2333	competence protein COMEC
SAVC_RS07675	COG0658	competence protein
SAVC_RS07680	COG2131	deaminase
SAVC_RS07690	COG2226	methyltransferase
SAVC_RS07695	COG0799	negative regulation of ribosome biogenesis
SAVC_RS07700	COG1713	HD superfamily hydrolase involved in NAD metabolism
SAVC_RS07710	COG1534	Rna-binding protein
SAVC_RS07720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SAVC_RS07725	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SAVC_RS07750	COG3177	Filamentation induced by cAMP protein fic
SAVC_RS07755	COG1914	H( )-stimulated, divalent metal cation uptake system
SAVC_RS07765	COG0439	Biotin carboxylase
SAVC_RS07770	COG0511	ligase activity, forming carbon-carbon bonds
SAVC_RS07775	COG1984	allophanate hydrolase subunit 2
SAVC_RS07780	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SAVC_RS07795	COG0826	peptidase U32
SAVC_RS07800	COG0826	peptidase U32
SAVC_RS07830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SAVC_RS07845	COG1104	cysteine desulfurase activity
SAVC_RS07850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SAVC_RS07860	COG3237	CsbD-like
SAVC_RS07865	COG1959	2 iron, 2 sulfur cluster binding
SAVC_RS07870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SAVC_RS07875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SAVC_RS07885	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SAVC_RS07915	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SAVC_RS07915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SAVC_RS07920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAVC_RS07920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SAVC_RS07925	COG1862	Preprotein translocase
SAVC_RS07965	COG2868	ribosomal protein
SAVC_RS08005	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SAVC_RS08015	COG0285	dihydrofolate synthase activity
SAVC_RS08025	COG2818	Glycosylase
SAVC_RS08060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SAVC_RS08065	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SAVC_RS08095	COG4112	unkown
SAVC_RS08120	COG0833	amino acid
SAVC_RS08125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SAVC_RS08135	COG1484	DNA-dependent DNA replication
SAVC_RS08165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAVC_RS08165	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SAVC_RS08175	COG5002	protein histidine kinase activity
SAVC_RS08180	COG0745	RESPONSE REGULATOR receiver
SAVC_RS08195	COG0372	Belongs to the citrate synthase family
SAVC_RS08200	COG1113	amino acid transport
SAVC_RS08235	COG0281	malic enzyme
SAVC_RS08240	COG0587	DNA-directed DNA polymerase activity
SAVC_RS08245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SAVC_RS08250	COG4109	DRTGG domain
SAVC_RS08290	COG0827	DNA restriction-modification system
SAVC_RS08310	COG1104	cysteine desulfurase activity
SAVC_RS08325	COG1956	GAF domain-containing protein
SAVC_RS08340	COG0584	glycerophosphoryl diester phosphodiesterase
SAVC_RS08345	COG1764	response to oxidative stress
SAVC_RS08350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SAVC_RS08355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAVC_RS08370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAVC_RS08370	COG1263	PTS System
SAVC_RS08375	COG0204	Acyl-transferase
SAVC_RS08380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SAVC_RS08400	COG5386	Cell surface protein
SAVC_RS08410	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SAVC_RS08415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAVC_RS08420	COG0454	-acetyltransferase
SAVC_RS08440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SAVC_RS08440	COG1605	Chorismate mutase
SAVC_RS08465	COG1674	ftsk spoiiie
SAVC_RS08470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SAVC_RS08480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SAVC_RS08485	COG1363	Peptidase, m42
SAVC_RS08495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SAVC_RS08505	COG0510	thiamine kinase activity
SAVC_RS08525	COG1187	pseudouridine synthase activity
SAVC_RS08530	COG2244	polysaccharide biosynthetic process
SAVC_RS08535	COG2081	HI0933 family
SAVC_RS08555	COG2814	Major facilitator Superfamily
SAVC_RS08560	COG1242	4 iron, 4 sulfur cluster binding
SAVC_RS08565	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SAVC_RS08585	COG2267	carboxylic ester hydrolase activity
SAVC_RS08615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAVC_RS08615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SAVC_RS08650	COG1595	DNA-templated transcription, initiation
SAVC_RS08670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SAVC_RS08700	COG0656	L-ascorbic acid biosynthetic process
SAVC_RS08725	COG1506	peptidase
SAVC_RS08890	COG1131	(ABC) transporter
SAVC_RS08995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SAVC_RS09000	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SAVC_RS09025	COG1131	(ABC) transporter
SAVC_RS09030	COG0537	adenosine 5'-monophosphoramidase activity
SAVC_RS09060	COG0420	3'-5' exonuclease activity
SAVC_RS09085	COG2197	response regulator
SAVC_RS09090	COG2203	Gaf domain
SAVC_RS09090	COG4585	Histidine kinase
SAVC_RS09130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SAVC_RS09135	COG1126	abc transporter atp-binding protein
SAVC_RS09140	COG0765	amino acid transport
SAVC_RS09310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SAVC_RS09315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SAVC_RS09325	COG4129	membrane
SAVC_RS09350	COG1988	membrane-bound metal-dependent
SAVC_RS09365	COG1388	LysM domain
SAVC_RS09365	COG1134	teichoic acid transport
SAVC_RS09395	COG0535	radical SAM domain protein
SAVC_RS09400	COG1607	acyl-coa hydrolase
SAVC_RS09405	COG2309	aminopeptidase activity
SAVC_RS09425	COG1295	ribonuclease BN
SAVC_RS09430	COG2197	response regulator
SAVC_RS09545	COG4851	CamS sex pheromone cAM373 precursor
SAVC_RS09555	COG0210	DNA helicase
SAVC_RS09565	COG4496	protein, YerC YecD
SAVC_RS09600	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SAVC_RS09610	COG0077	Prephenate dehydratase
SAVC_RS09620	COG0471	metal ion transport
SAVC_RS09630	COG1335	isochorismatase
SAVC_RS09645	COG1012	belongs to the aldehyde dehydrogenase family
SAVC_RS09695	COG1131	(ABC) transporter
SAVC_RS09710	COG1725	Transcriptional regulator
SAVC_RS09765	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SAVC_RS09770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SAVC_RS09775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SAVC_RS09790	COG3728	DNA packaging
SAVC_RS09790	COG5484	DNA packaging
SAVC_RS09865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SAVC_RS09870	COG1621	beta-fructofuranosidase activity
SAVC_RS09875	COG1609	Transcriptional regulator
SAVC_RS09880	COG0004	ammonium transporteR
SAVC_RS09885	COG0425	Belongs to the sulfur carrier protein TusA family
SAVC_RS09890	COG2391	methyltransferase activity
SAVC_RS09900	COG0488	(ABC) transporter
SAVC_RS09910	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SAVC_RS09920	COG0456	acetyltransferase
SAVC_RS09925	COG1214	PFAM Peptidase M22, glycoprotease
SAVC_RS09930	COG0802	atpase or kinase
SAVC_RS09945	COG0028	Belongs to the TPP enzyme family
SAVC_RS09965	COG0473	3-isopropylmalate dehydrogenase activity
SAVC_RS10020	COG2183	response to ionizing radiation
SAVC_RS10025	COG1191	sigma factor activity
SAVC_RS10035	COG1366	Belongs to the anti-sigma-factor antagonist family
SAVC_RS10040	COG2208	phosphoserine phosphatase activity
SAVC_RS10080	COG3428	Bacterial PH domain
SAVC_RS10110	COG2205	protein histidine kinase activity
SAVC_RS10115	COG0745	RESPONSE REGULATOR receiver
SAVC_RS10125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SAVC_RS10135	COG0772	Belongs to the SEDS family
SAVC_RS10150	COG1937	Protein conserved in bacteria
SAVC_RS10160	COG1418	mRNA catabolic process
SAVC_RS10195	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SAVC_RS10210	COG0629	single-stranded DNA binding
SAVC_RS10285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SAVC_RS10310	COG0009	L-threonylcarbamoyladenylate synthase
SAVC_RS10315	COG2890	protein-(glutamine-N5) methyltransferase activity
SAVC_RS10335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SAVC_RS10365	COG0504	CTP synthase activity
SAVC_RS10375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SAVC_RS10430	COG0813	purine-nucleoside phosphorylase activity
SAVC_RS10435	COG0783	Belongs to the Dps family
SAVC_RS10455	COG1482	cell wall glycoprotein biosynthetic process
SAVC_RS10465	COG0702	epimerase
SAVC_RS10470	COG0640	Transcriptional regulator
SAVC_RS10505	COG0561	phosphatase activity
SAVC_RS10510	COG1119	ATPase activity
SAVC_RS10525	COG3711	transcriptional antiterminator
SAVC_RS10535	COG0246	Mannitol dehydrogenase
SAVC_RS10555	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SAVC_RS10625	COG0489	protein tyrosine kinase activity
SAVC_RS10630	COG2814	Major facilitator Superfamily
SAVC_RS10645	COG1272	protein, Hemolysin III
SAVC_RS10655	COG1988	membrane-bound metal-dependent
SAVC_RS10665	COG3314	Sporulation integral membrane protein YlbJ
SAVC_RS10670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAVC_RS10675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SAVC_RS10680	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SAVC_RS10690	COG3457	Alanine racemase
SAVC_RS10695	COG4264	IucA IucC family
SAVC_RS10700	COG2814	Major facilitator Superfamily
SAVC_RS10740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAVC_RS10750	COG2130	NADP-dependent
SAVC_RS10800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SAVC_RS10820	COG0656	L-ascorbic acid biosynthetic process
SAVC_RS10825	COG0789	Transcriptional regulator
SAVC_RS10835	COG5492	domain, Protein
SAVC_RS10855	COG3527	Alpha-acetolactate decarboxylase
SAVC_RS10860	COG0028	Belongs to the TPP enzyme family
SAVC_RS10880	COG0542	response to heat
SAVC_RS10970	COG0201	protein transport
SAVC_RS11085	COG2252	PERMEase
SAVC_RS11090	COG0551	DNA topoisomerase type I activity
SAVC_RS11090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SAVC_RS11130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SAVC_RS11200	COG1763	Mo-molybdopterin cofactor biosynthetic process
SAVC_RS11220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SAVC_RS11225	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
SAVC_RS11230	COG4149	molybdate abc transporter
SAVC_RS11250	COG1268	BioY protein
SAVC_RS11265	COG1960	acyl-CoA dehydrogenase activity
SAVC_RS11270	COG4413	Urea transporter
SAVC_RS11335	COG3942	CHAP domain
SAVC_RS11345	COG1757	Na H antiporter
SAVC_RS11360	COG3942	CHAP domain
SAVC_RS11435	COG1113	amino acid transport
SAVC_RS11455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SAVC_RS11460	COG0385	Bile acid
SAVC_RS11470	COG1263	PTS System
SAVC_RS11470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAVC_RS11475	COG1737	Transcriptional regulator
SAVC_RS11495	COG1028	Short-chain dehydrogenase reductase Sdr
SAVC_RS11500	COG1473	amidohydrolase
SAVC_RS11515	COG0583	DNA-binding transcription factor activity
SAVC_RS11540	COG2258	MOSC domain
SAVC_RS11560	COG1668	transmembrane transport
SAVC_RS11565	COG4152	abc transporter atp-binding protein
SAVC_RS11570	COG3152	Membrane
SAVC_RS11580	COG0786	glutamate:sodium symporter activity
SAVC_RS11590	COG0598	Magnesium transport protein CorA
SAVC_RS11605	COG0657	acetylesterase activity
SAVC_RS11615	COG2814	Major facilitator Superfamily
SAVC_RS11620	COG1566	PFAM secretion protein HlyD family protein
SAVC_RS11630	COG2814	Major facilitator Superfamily
SAVC_RS11700	COG1620	l-lactate permease
SAVC_RS11720	COG0604	alcohol dehydrogenase
SAVC_RS11725	COG0456	acetyltransferase
SAVC_RS11750	COG1511	domain protein
SAVC_RS11765	COG1263	PTS System
SAVC_RS11765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SAVC_RS11780	COG3871	stress protein (general stress protein 26)
SAVC_RS11820	COG0789	Transcriptional regulator
SAVC_RS11840	COG2181	nitrate reductase activity
SAVC_RS11850	COG1140	nitrate reductase beta subunit
SAVC_RS11855	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SAVC_RS11865	COG2146	nitrite reductase [NAD(P)H] activity
SAVC_RS11870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SAVC_RS11880	COG0454	-acetyltransferase
SAVC_RS11885	COG2116	formate transmembrane transporter activity
SAVC_RS11900	COG0803	Belongs to the bacterial solute-binding protein 9 family
SAVC_RS11900	COG3443	Belongs to the bacterial solute-binding protein 9 family
SAVC_RS11935	COG1126	abc transporter atp-binding protein
SAVC_RS11940	COG0765	amino acid transport
SAVC_RS11945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SAVC_RS11950	COG2814	Major facilitator Superfamily
SAVC_RS11970	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SAVC_RS12015	COG0156	8-amino-7-oxononanoate synthase activity
SAVC_RS12025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SAVC_RS12030	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SAVC_RS12045	COG1132	(ABC) transporter
SAVC_RS12050	COG2375	cellular response to nickel ion
SAVC_RS12050	COG1132	(ABC) transporter
SAVC_RS12070	COG1929	Belongs to the glycerate kinase type-1 family
SAVC_RS12080	COG2814	Major facilitator Superfamily
SAVC_RS12100	COG1113	amino acid transport
SAVC_RS12115	COG0531	amino acid
SAVC_RS12125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SAVC_RS12140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAVC_RS12150	COG1174	glycine betaine transport
SAVC_RS12160	COG1174	glycine betaine transport
SAVC_RS12180	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SAVC_RS12185	COG0531	amino acid
SAVC_RS12190	COG2272	Belongs to the type-B carboxylesterase lipase family
SAVC_RS12195	COG2814	Major facilitator Superfamily
SAVC_RS12200	COG0390	transport system, permease component
SAVC_RS12205	COG4619	ABC transporter
SAVC_RS12210	COG1363	Peptidase, m42
SAVC_RS12230	COG4808	Protein conserved in bacteria
SAVC_RS12235	COG0069	glutamate synthase activity
SAVC_RS12250	COG1124	(ABC) transporter
SAVC_RS12255	COG0444	Belongs to the ABC transporter superfamily
SAVC_RS12260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SAVC_RS12265	COG0601	transmembrane transport
SAVC_RS12270	COG0747	negative chemotaxis
SAVC_RS12300	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
SAVC_RS12305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SAVC_RS12390	COG0494	nUDIX hydrolase
SAVC_RS12420	COG3583	domain protein
SAVC_RS12425	COG1846	Transcriptional regulator
SAVC_RS12430	COG1846	Transcriptional regulator
SAVC_RS12445	COG4932	domain protein
SAVC_RS12465	COG1070	Carbohydrate kinase
SAVC_RS12470	COG1802	Transcriptional regulator
SAVC_RS12475	COG0789	Transcriptional regulator
SAVC_RS12480	COG2357	RelA SpoT domain protein
SAVC_RS12485	COG4876	unkown
SAVC_RS12495	COG2271	Major facilitator Superfamily
SAVC_RS12500	COG0586	Pfam SNARE associated Golgi protein
SAVC_RS12510	COG2814	Major facilitator Superfamily
SAVC_RS12515	COG1846	Transcriptional regulator
SAVC_RS12520	COG1131	(ABC) transporter
SAVC_RS12540	COG3949	Membrane
SAVC_RS12545	COG0400	carboxylic ester hydrolase activity
SAVC_RS12550	COG0346	lactoylglutathione lyase activity
SAVC_RS12555	COG1846	Transcriptional regulator
SAVC_RS12565	COG2514	catechol 2,3-dioxygenase activity
SAVC_RS12580	COG0561	phosphatase activity
SAVC_RS12585	COG1131	(ABC) transporter
SAVC_RS12595	COG3764	Sortase (surface protein transpeptidase)
SAVC_RS12615	COG1760	l-serine dehydratase
SAVC_RS12620	COG1760	l-serine dehydratase
SAVC_RS12635	COG0697	spore germination
SAVC_RS12640	COG0657	acetylesterase activity
SAVC_RS12660	COG0028	Belongs to the TPP enzyme family
SAVC_RS12675	COG0583	DNA-binding transcription factor activity
SAVC_RS12685	COG3942	CHAP domain
SAVC_RS12710	COG3425	synthase
SAVC_RS12715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SAVC_RS12720	COG0542	response to heat
SAVC_RS12740	COG2409	Drug exporters of the RND superfamily
SAVC_RS12785	COG0436	Aminotransferase
SAVC_RS12815	COG3942	CHAP domain
SAVC_RS12820	COG2755	lipolytic protein G-D-S-L family
SAVC_RS12820	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SAVC_RS12850	COG1309	transcriptional regulator
SAVC_RS12895	COG0596	Alpha beta hydrolase
SAVC_RS12930	COG3001	Fructosamine kinase
SAVC_RS12935	COG0167	dihydroorotate dehydrogenase activity
SAVC_RS12975	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SAVC_RS12985	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SAVC_RS12990	COG3527	Alpha-acetolactate decarboxylase
SAVC_RS13005	COG0531	amino acid
SAVC_RS13035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SAVC_RS13055	COG1012	belongs to the aldehyde dehydrogenase family
SAVC_RS13065	COG1510	regulation of RNA biosynthetic process
SAVC_RS13075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SAVC_RS13100	COG2851	Citrate transporter
SAVC_RS13115	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SAVC_RS13125	COG0386	Belongs to the glutathione peroxidase family
SAVC_RS13150	COG1136	(ABC) transporter
SAVC_RS13155	COG2205	protein histidine kinase activity
SAVC_RS13175	COG1785	Belongs to the alkaline phosphatase family
SAVC_RS13180	COG1846	Transcriptional regulator
SAVC_RS13225	COG1438	arginine binding
SAVC_RS13245	COG3711	transcriptional antiterminator
SAVC_RS13245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAVC_RS13250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SAVC_RS13250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAVC_RS13250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SAVC_RS13255	COG1482	cell wall glycoprotein biosynthetic process
SAVC_RS13265	COG3942	CHAP domain
SAVC_RS13265	COG1705	Flagellar rod assembly protein muramidase FlgJ
SAVC_RS13270	COG1535	isochorismatase
SAVC_RS13270	COG3433	isochorismatase activity
SAVC_RS13285	COG0438	transferase activity, transferring glycosyl groups
SAVC_RS13300	COG1073	alpha beta
SAVC_RS13320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAVC_RS13340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SAVC_RS13395	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SAVC_RS13430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SAVC_RS13515	COG0471	metal ion transport
SAVC_RS13520	COG2962	Rard protein
SAVC_RS13530	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
SAVC_RS13545	COG1136	(ABC) transporter
SAVC_RS13550	COG0577	efflux transmembrane transporter activity
SAVC_RS13575	COG1278	Cold shock
SAVC_RS13595	COG1475	DNA binding