locus-tag	class	description
CNH35_RS00015	COG2501	S4 domain
CNH35_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CNH35_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNH35_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CNH35_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
CNH35_RS00120	COG4863	YycH protein
CNH35_RS00130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CNH35_RS00135	COG0737	Belongs to the 5'-nucleotidase family
CNH35_RS00170	COG0730	response to heat
CNH35_RS00175	COG1937	Protein conserved in bacteria
CNH35_RS00180	COG2210	Belongs to the sulfur carrier protein TusA family
CNH35_RS00185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNH35_RS00225	COG0655	NAD(P)H dehydrogenase (quinone) activity
CNH35_RS00240	COG0583	DNA-binding transcription factor activity
CNH35_RS00260	COG0823	Involved in the tonB-independent uptake of proteins
CNH35_RS00290	COG1473	amidohydrolase
CNH35_RS00300	COG1283	sodium-dependent phosphate transmembrane transporter activity
CNH35_RS00305	COG4716	Myosin-crossreactive antigen
CNH35_RS00310	COG0697	spore germination
CNH35_RS00325	COG1620	l-lactate permease
CNH35_RS00345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNH35_RS00350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNH35_RS00355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CNH35_RS00365	COG2423	ornithine cyclodeaminase activity
CNH35_RS00370	COG4264	IucA IucC family
CNH35_RS00375	COG2814	Major facilitator Superfamily
CNH35_RS00380	COG4264	IucA IucC family
CNH35_RS00385	COG4264	IucA IucC family
CNH35_RS00395	COG0019	diaminopimelate decarboxylase activity
CNH35_RS00400	COG1475	DNA binding
CNH35_RS00430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CNH35_RS00435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CNH35_RS00440	COG0438	transferase activity, transferring glycosyl groups
CNH35_RS00475	COG0813	purine-nucleoside phosphorylase activity
CNH35_RS00480	COG2814	Major facilitator Superfamily
CNH35_RS00500	COG3639	organic phosphonate transmembrane transporter activity
CNH35_RS00520	COG0737	Belongs to the 5'-nucleotidase family
CNH35_RS00550	COG1012	belongs to the aldehyde dehydrogenase family
CNH35_RS00550	COG1454	alcohol dehydrogenase
CNH35_RS00575	COG1086	Polysaccharide biosynthesis protein
CNH35_RS00585	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CNH35_RS00615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CNH35_RS00625	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CNH35_RS00630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CNH35_RS00640	COG2832	Protein of unknown function (DUF454)
CNH35_RS00675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNH35_RS00680	COG1960	acyl-CoA dehydrogenase activity
CNH35_RS00685	COG5609	conserved protein (DUF2294)
CNH35_RS00735	COG1114	Component of the transport system for branched-chain amino acids
CNH35_RS00740	COG1335	isochorismatase
CNH35_RS00745	COG3961	Belongs to the TPP enzyme family
CNH35_RS00775	COG1737	Transcriptional regulator
CNH35_RS00815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNH35_RS00825	COG0405	Gamma-glutamyltransferase
CNH35_RS00845	COG3842	ATPase activity
CNH35_RS00855	COG1175	transmembrane transport
CNH35_RS00860	COG3833	ABC-type maltose transport systems, permease component
CNH35_RS00865	COG0673	inositol 2-dehydrogenase activity
CNH35_RS00870	COG0673	inositol 2-dehydrogenase activity
CNH35_RS00880	COG1755	Isoprenylcysteine carboxyl methyltransferase
CNH35_RS00940	COG0183	Belongs to the thiolase family
CNH35_RS00950	COG1960	acyl-CoA dehydrogenase activity
CNH35_RS00955	COG0318	PFAM AMP-dependent synthetase and ligase
CNH35_RS00970	COG0747	negative chemotaxis
CNH35_RS00975	COG3189	MarR family transcriptional regulator
CNH35_RS01010	COG2190	(PTS) system
CNH35_RS01010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNH35_RS01010	COG1263	PTS System
CNH35_RS01015	COG1957	nucleoside hydrolase
CNH35_RS01035	COG3414	Phosphotransferase system galactitol-specific IIB component
CNH35_RS01040	COG3775	system Galactitol-specific IIC component
CNH35_RS01045	COG1063	alcohol dehydrogenase
CNH35_RS01055	COG1063	alcohol dehydrogenase
CNH35_RS01060	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CNH35_RS01065	COG1063	alcohol dehydrogenase
CNH35_RS01070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CNH35_RS01075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CNH35_RS01085	COG1063	alcohol dehydrogenase
CNH35_RS01090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CNH35_RS01125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNH35_RS01135	COG1263	PTS System
CNH35_RS01135	COG2190	(PTS) system
CNH35_RS01135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNH35_RS01140	COG2723	6-phospho-beta-galactosidase activity
CNH35_RS01150	COG2226	methyltransferase
CNH35_RS01205	COG0739	heme binding
CNH35_RS01240	COG3942	CHAP domain
CNH35_RS01240	COG1388	LysM domain
CNH35_RS01400	COG1114	Component of the transport system for branched-chain amino acids
CNH35_RS01410	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CNH35_RS01420	COG0577	efflux transmembrane transporter activity
CNH35_RS01450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CNH35_RS01455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNH35_RS01485	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CNH35_RS01485	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CNH35_RS01490	COG0582	viral genome integration into host DNA
CNH35_RS01585	COG1484	DNA-dependent DNA replication
CNH35_RS01820	COG0860	N-Acetylmuramoyl-L-alanine amidase
CNH35_RS01820	COG1388	LysM domain
CNH35_RS01830	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CNH35_RS01830	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CNH35_RS01850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNH35_RS01880	COG3037	sugar-specific permease SgaT UlaA
CNH35_RS01890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNH35_RS01920	COG2271	Major facilitator Superfamily
CNH35_RS01925	COG0346	lactoylglutathione lyase activity
CNH35_RS01930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNH35_RS01935	COG0431	NADPH-dependent FMN reductase
CNH35_RS01950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNH35_RS01955	COG2822	iron ion transport
CNH35_RS01960	COG2837	iron assimilation
CNH35_RS01965	COG0672	)-iron permease
CNH35_RS01970	COG0805	protein transport
CNH35_RS01975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CNH35_RS01985	COG1476	TRANSCRIPTIONal
CNH35_RS02025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CNH35_RS02025	COG0646	methionine synthase
CNH35_RS02030	COG0626	cystathionine gamma-synthase activity
CNH35_RS02035	COG0626	cystathionine gamma-synthase activity
CNH35_RS02045	COG1475	DNA binding
CNH35_RS02050	COG0668	transmembrane transport
CNH35_RS02055	COG4481	Protein conserved in bacteria
CNH35_RS02060	COG0012	GTP binding
CNH35_RS02095	COG4974	Belongs to the 'phage' integrase family
CNH35_RS02155	COG3634	alkyl hydroperoxide reductase activity
CNH35_RS02170	COG1823	symporter activity
CNH35_RS02205	COG2233	PERMEase
CNH35_RS02245	COG3759	membrane
CNH35_RS02410	COG0523	cobalamin synthesis protein
CNH35_RS02440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CNH35_RS02445	COG3002	Belongs to the UPF0753 family
CNH35_RS02450	COG5609	conserved protein (DUF2294)
CNH35_RS02465	COG1647	Serine aminopeptidase, S33
CNH35_RS02475	COG0733	neurotransmitter:sodium symporter activity
CNH35_RS02480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CNH35_RS02485	COG0626	cystathionine gamma-synthase activity
CNH35_RS02495	COG2011	ABC-type metal ion transport system permease component
CNH35_RS02500	COG1464	Belongs to the NlpA lipoprotein family
CNH35_RS02535	COG0583	DNA-binding transcription factor activity
CNH35_RS02540	COG0067	glutamate synthase
CNH35_RS02540	COG0069	glutamate synthase activity
CNH35_RS02540	COG0070	glutamate synthase
CNH35_RS02545	COG0493	'glutamate synthase
CNH35_RS02555	COG1263	PTS System
CNH35_RS02555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNH35_RS02560	COG0366	Alpha amylase catalytic
CNH35_RS02565	COG2188	Transcriptional regulator
CNH35_RS02585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CNH35_RS02590	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CNH35_RS02625	COG1982	Orn Lys Arg decarboxylase major
CNH35_RS02635	COG3870	Protein conserved in bacteria
CNH35_RS02640	COG0470	DNA polymerase III
CNH35_RS02645	COG1774	PSP1 C-terminal conserved region
CNH35_RS02655	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CNH35_RS02665	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CNH35_RS02675	COG0084	hydrolase, TatD family'
CNH35_RS02680	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CNH35_RS02690	COG4466	Protein conserved in bacteria
CNH35_RS02700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CNH35_RS02705	COG0251	oxidation-reduction process
CNH35_RS02750	COG2244	polysaccharide biosynthetic process
CNH35_RS02755	COG3956	TIGRFAM MazG family protein
CNH35_RS02760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CNH35_RS02770	COG1098	S1 RNA binding domain
CNH35_RS02785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNH35_RS02810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CNH35_RS02890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNH35_RS02905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CNH35_RS02915	COG3880	PFAM UvrB UvrC protein
CNH35_RS02930	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CNH35_RS02935	COG4956	integral membrane protein (PIN domain superfamily)
CNH35_RS02960	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CNH35_RS02990	COG0250	Participates in transcription elongation, termination and antitermination
CNH35_RS03020	COG2813	Specifically methylates the guanine in position
CNH35_RS03030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CNH35_RS03060	COG1473	amidohydrolase
CNH35_RS03095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CNH35_RS03100	COG1428	Deoxynucleoside kinase
CNH35_RS03105	COG1428	Deoxynucleoside kinase
CNH35_RS03115	COG0561	phosphatase activity
CNH35_RS03160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CNH35_RS03175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CNH35_RS03275	COG0095	Lipoate-protein ligase
CNH35_RS03280	COG0083	homoserine kinase activity
CNH35_RS03300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CNH35_RS03395	COG0667	Aldo Keto reductase
CNH35_RS03400	COG0655	NAD(P)H dehydrogenase (quinone) activity
CNH35_RS03410	COG1078	dGTPase activity
CNH35_RS03450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CNH35_RS03505	COG4974	Belongs to the 'phage' integrase family
CNH35_RS03550	COG0803	Belongs to the bacterial solute-binding protein 9 family
CNH35_RS03555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CNH35_RS03560	COG1121	(ABC) transporter
CNH35_RS03565	COG1321	iron dependent repressor
CNH35_RS03575	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CNH35_RS03585	COG1682	transport, permease protein
CNH35_RS03590	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CNH35_RS03595	COG1216	Glycosyl transferase, family 2
CNH35_RS03600	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CNH35_RS03605	COG1686	Belongs to the peptidase S11 family
CNH35_RS03610	COG1132	(ABC) transporter
CNH35_RS03615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CNH35_RS03625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CNH35_RS03630	COG1120	ATPase activity
CNH35_RS03635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNH35_RS03640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNH35_RS03645	COG2376	Dihydroxyacetone kinase
CNH35_RS03655	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CNH35_RS03665	COG3949	Membrane
CNH35_RS03705	COG1136	(ABC) transporter
CNH35_RS03710	COG0577	efflux transmembrane transporter activity
CNH35_RS03715	COG1392	Phosphate transport regulator
CNH35_RS03720	COG0306	phosphate transporter
CNH35_RS03725	COG1388	LysM domain
CNH35_RS03725	COG3942	CHAP domain
CNH35_RS03735	COG1917	Cupin 2, conserved barrel domain protein
CNH35_RS03735	COG4977	sequence-specific DNA binding
CNH35_RS03765	COG0583	DNA-binding transcription factor activity
CNH35_RS03775	COG2814	Major facilitator Superfamily
CNH35_RS03780	COG2839	Protein conserved in bacteria
CNH35_RS03810	COG1611	Belongs to the LOG family
CNH35_RS03830	COG4988	ABC transporter
CNH35_RS03835	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CNH35_RS03840	COG1846	Transcriptional regulator
CNH35_RS03845	COG0523	cobalamin synthesis protein
CNH35_RS03850	COG4989	oxidoreductase activity
CNH35_RS03860	COG0471	metal ion transport
CNH35_RS03895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CNH35_RS03900	COG1349	DNA-binding transcription factor activity
CNH35_RS03905	COG1105	Belongs to the carbohydrate kinase PfkB family
CNH35_RS03910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNH35_RS03910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CNH35_RS03910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CNH35_RS03915	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CNH35_RS03920	COG1253	flavin adenine dinucleotide binding
CNH35_RS03925	COG0656	L-ascorbic acid biosynthetic process
CNH35_RS03930	COG0463	Glycosyl transferase, family 2
CNH35_RS03965	COG0720	synthase
CNH35_RS03975	COG0512	Glutamine amidotransferase of anthranilate synthase
CNH35_RS03975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CNH35_RS03980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CNH35_RS04010	COG0488	(ABC) transporter
CNH35_RS04015	COG0514	ATP-dependent DNA helicase (RecQ)
CNH35_RS04020	COG1125	glycine betaine transport
CNH35_RS04020	COG0517	IMP dehydrogenase activity
CNH35_RS04025	COG1174	glycine betaine transport
CNH35_RS04055	COG3104	oligopeptide transport
CNH35_RS04085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNH35_RS04090	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNH35_RS04105	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNH35_RS04110	COG4605	iron ion homeostasis
CNH35_RS04115	COG4604	ABC transporter, ATP-binding protein
CNH35_RS04120	COG4607	ABC-type enterochelin transport system periplasmic component
CNH35_RS04175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNH35_RS04180	COG1739	Uncharacterized protein family UPF0029
CNH35_RS04190	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CNH35_RS04195	COG1040	competence protein
CNH35_RS04225	COG1388	LysM domain
CNH35_RS04225	COG3942	CHAP domain
CNH35_RS04285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CNH35_RS04350	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CNH35_RS04355	COG1647	Serine aminopeptidase, S33
CNH35_RS04360	COG0557	exoribonuclease II activity
CNH35_RS04435	COG1278	Cold shock
CNH35_RS04475	COG0406	alpha-ribazole phosphatase activity
CNH35_RS04480	COG1279	arginine transmembrane transporter activity
CNH35_RS04505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNH35_RS04510	COG1393	Belongs to the ArsC family
CNH35_RS04525	COG3878	Protein conserved in bacteria
CNH35_RS04535	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CNH35_RS04550	COG2011	ABC-type metal ion transport system permease component
CNH35_RS04555	COG1464	Belongs to the NlpA lipoprotein family
CNH35_RS04570	COG0396	ATPase activity
CNH35_RS04575	COG0719	Fe-S assembly protein
CNH35_RS04585	COG0822	iron-sulfur transferase activity
CNH35_RS04610	COG1253	flavin adenine dinucleotide binding
CNH35_RS04625	COG1801	Protein of unknown function DUF72
CNH35_RS04630	COG0730	response to heat
CNH35_RS04645	COG4470	Protein conserved in bacteria
CNH35_RS04655	COG2445	Protein of unknown function DUF86
CNH35_RS04685	COG1696	Membrane protein involved in D-alanine export
CNH35_RS04695	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CNH35_RS04700	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CNH35_RS04705	COG4837	Protein of unknown function (DUF1462)
CNH35_RS04710	COG1252	NADH dehydrogenase
CNH35_RS04730	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CNH35_RS04735	COG2056	Na+-H+ antiporter family
CNH35_RS04740	COG2050	protein possibly involved in aromatic compounds catabolism
CNH35_RS04795	COG1098	S1 RNA binding domain
CNH35_RS04800	COG1902	pentaerythritol trinitrate reductase activity
CNH35_RS04820	COG0584	glycerophosphoryl diester phosphodiesterase
CNH35_RS04840	COG0398	Pfam SNARE associated Golgi protein
CNH35_RS04860	COG1074	ATP-dependent DNA helicase activity
CNH35_RS04880	COG0561	phosphatase activity
CNH35_RS04920	COG1881	PFAM PEBP family protein
CNH35_RS04950	COG0601	transmembrane transport
CNH35_RS04955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNH35_RS04960	COG0444	Belongs to the ABC transporter superfamily
CNH35_RS04965	COG4608	Belongs to the ABC transporter superfamily
CNH35_RS04970	COG4166	transmembrane transport
CNH35_RS04975	COG0747	negative chemotaxis
CNH35_RS04980	COG0444	Belongs to the ABC transporter superfamily
CNH35_RS04985	COG4608	Belongs to the ABC transporter superfamily
CNH35_RS04990	COG0601	transmembrane transport
CNH35_RS04995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNH35_RS05020	COG1164	Oligoendopeptidase f
CNH35_RS05030	COG2346	COG2346, Truncated hemoglobins
CNH35_RS05045	COG2357	RelA SpoT domain protein
CNH35_RS05055	COG0564	pseudouridine synthase activity
CNH35_RS05060	COG2239	Acts as a magnesium transporter
CNH35_RS05065	COG0569	domain protein
CNH35_RS05065	COG0475	glutathione-regulated potassium exporter activity
CNH35_RS05075	COG0628	permease
CNH35_RS05080	COG1115	amino acid carrier protein
CNH35_RS05120	COG0861	Integral membrane protein TerC family
CNH35_RS05130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CNH35_RS05135	COG0737	Belongs to the 5'-nucleotidase family
CNH35_RS05150	COG4903	ComK protein
CNH35_RS05165	COG4873	Protein conserved in bacteria
CNH35_RS05225	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CNH35_RS05235	COG2314	TM2 domain
CNH35_RS05240	COG0456	acetyltransferase
CNH35_RS05245	COG1575	Belongs to the MenA family. Type 1 subfamily
CNH35_RS05255	COG1169	isochorismate synthase
CNH35_RS05265	COG2267	carboxylic ester hydrolase activity
CNH35_RS05285	COG3591	Belongs to the peptidase S1B family
CNH35_RS05290	COG0436	Aminotransferase
CNH35_RS05295	COG3594	Acyltransferase
CNH35_RS05315	COG2153	protein acetylation
CNH35_RS05325	COG1316	TRANSCRIPTIONal
CNH35_RS05330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CNH35_RS05370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CNH35_RS05385	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CNH35_RS05425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CNH35_RS05430	COG4172	Belongs to the ABC transporter superfamily
CNH35_RS05435	COG4721	ABC-type cobalt transport system, permease component
CNH35_RS05460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CNH35_RS05485	COG1271	oxidase subunit
CNH35_RS05490	COG1294	oxidase, subunit
CNH35_RS05495	COG0569	domain protein
CNH35_RS05560	COG1176	ABC-type spermidine putrescine transport system, permease component I
CNH35_RS05565	COG1177	transmembrane transport
CNH35_RS05570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CNH35_RS05595	COG0483	inositol monophosphate 1-phosphatase activity
CNH35_RS05615	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CNH35_RS05625	COG0772	Belongs to the SEDS family
CNH35_RS05630	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CNH35_RS05660	COG3679	Belongs to the UPF0342 family
CNH35_RS05680	COG0742	ribosomal rna small subunit methyltransferase
CNH35_RS05795	COG1484	DNA-dependent DNA replication
CNH35_RS05895	COG1783	phage Terminase large subunit
CNH35_RS06025	COG5632	N-Acetylmuramoyl-L-alanine amidase
CNH35_RS06025	COG1388	LysM domain
CNH35_RS06060	COG4509	Sortase family
CNH35_RS06075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNH35_RS06110	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CNH35_RS06110	COG1796	DNA polymerase
CNH35_RS06135	COG2009	succinate dehydrogenase
CNH35_RS06140	COG1053	succinate dehydrogenase
CNH35_RS06145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CNH35_RS06260	COG1288	antiporter activity
CNH35_RS06295	COG1011	Hydrolase
CNH35_RS06320	COG4839	cell division protein FtsL
CNH35_RS06340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CNH35_RS06345	COG0849	cell division
CNH35_RS06350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CNH35_RS06360	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CNH35_RS06370	COG0762	integral membrane protein
CNH35_RS06375	COG2302	S4 RNA-binding domain
CNH35_RS06380	COG3599	regulation of cell shape
CNH35_RS06390	COG2514	catechol 2,3-dioxygenase activity
CNH35_RS06410	COG0564	pseudouridine synthase activity
CNH35_RS06420	COG2233	PERMEase
CNH35_RS06480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CNH35_RS06485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CNH35_RS06495	COG2314	TM2 domain
CNH35_RS06510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CNH35_RS06510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CNH35_RS06520	COG0631	protein serine/threonine phosphatase activity
CNH35_RS06535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CNH35_RS06550	COG1302	Protein conserved in bacteria
CNH35_RS06560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CNH35_RS06600	COG1196	nuclear chromosome segregation
CNH35_RS06605	COG0552	protein localization to endoplasmic reticulum
CNH35_RS06615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CNH35_RS06665	COG1388	LysM domain
CNH35_RS06675	COG0758	DNA mediated transformation
CNH35_RS06775	COG0195	Participates in both transcription termination and antitermination
CNH35_RS06780	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CNH35_RS06805	COG0196	riboflavin kinase activity
CNH35_RS06835	COG2188	Transcriptional regulator
CNH35_RS06840	COG0612	Peptidase, M16
CNH35_RS06845	COG0612	Peptidase, M16
CNH35_RS06850	COG0300	oxidoreductase activity
CNH35_RS06870	COG1058	Belongs to the CinA family
CNH35_RS06870	COG1546	Belongs to the CinA family
CNH35_RS06890	COG1692	metallophosphoesterase
CNH35_RS06895	COG0674	pyruvate-flavodoxin oxidoreductase activity
CNH35_RS06895	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CNH35_RS06900	COG1013	pyruvate-flavodoxin oxidoreductase activity
CNH35_RS06935	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CNH35_RS06940	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CNH35_RS06965	COG1923	regulation of RNA biosynthetic process
CNH35_RS06975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CNH35_RS06980	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CNH35_RS06985	COG0789	Transcriptional regulator
CNH35_RS07105	COG1131	(ABC) transporter
CNH35_RS07120	COG2197	response regulator
CNH35_RS07130	COG1525	nuclease
CNH35_RS07145	COG0527	aspartate kinase activity
CNH35_RS07150	COG0460	homoserine dehydrogenase
CNH35_RS07155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CNH35_RS07180	COG0833	amino acid
CNH35_RS07210	COG2340	Cysteine-rich secretory protein family
CNH35_RS07245	COG4846	Membrane protein involved in cytochrome C biogenesis
CNH35_RS07265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CNH35_RS07280	COG0824	Thioesterase
CNH35_RS07305	COG0187	DNA topoisomerase II activity
CNH35_RS07310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CNH35_RS07320	COG1115	amino acid carrier protein
CNH35_RS07335	COG0628	permease
CNH35_RS07340	COG0392	lysyltransferase activity
CNH35_RS07340	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CNH35_RS07345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CNH35_RS07350	COG1316	TRANSCRIPTIONal
CNH35_RS07360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CNH35_RS07370	COG1363	Peptidase, m42
CNH35_RS07375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CNH35_RS07380	COG0512	Glutamine amidotransferase of anthranilate synthase
CNH35_RS07410	COG2348	transferase activity, transferring amino-acyl groups
CNH35_RS07415	COG2348	transferase activity, transferring amino-acyl groups
CNH35_RS07420	COG0561	phosphatase activity
CNH35_RS07465	COG0704	Plays a role in the regulation of phosphate uptake
CNH35_RS07475	COG0581	inorganic phosphate transmembrane transporter activity
CNH35_RS07480	COG0573	inorganic phosphate transmembrane transporter activity
CNH35_RS07500	COG0488	(ABC) transporter
CNH35_RS07505	COG0527	aspartate kinase activity
CNH35_RS07510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CNH35_RS07535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CNH35_RS07590	COG4548	von Willebrand factor, type A
CNH35_RS07640	COG0671	phosphoesterase, PA-phosphatase related
CNH35_RS07645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CNH35_RS07675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CNH35_RS07700	COG1413	lyase activity
CNH35_RS07715	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CNH35_RS07740	COG0531	amino acid
CNH35_RS07755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CNH35_RS07760	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CNH35_RS07775	COG0116	Belongs to the methyltransferase superfamily
CNH35_RS07815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CNH35_RS07815	COG4499	WXG100 protein secretion system (Wss), protein YukC
CNH35_RS07825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CNH35_RS07830	COG3935	DnaD domain protein
CNH35_RS07855	COG0438	transferase activity, transferring glycosyl groups
CNH35_RS07860	COG1694	Mazg nucleotide pyrophosphohydrolase
CNH35_RS07865	COG2738	Putative neutral zinc metallopeptidase
CNH35_RS07870	COG4347	Protein of unknown function (DUF1405)
CNH35_RS07910	COG0142	geranyltranstransferase activity
CNH35_RS07975	COG0492	ferredoxin-NADP+ reductase activity
CNH35_RS07990	COG0514	ATP-dependent DNA helicase (RecQ)
CNH35_RS08000	COG1141	Ferredoxin
CNH35_RS08045	COG5002	protein histidine kinase activity
CNH35_RS08050	COG0745	RESPONSE REGULATOR receiver
CNH35_RS08055	COG1187	pseudouridine synthase activity
CNH35_RS08080	COG0735	belongs to the Fur family
CNH35_RS08085	COG0494	nUDIX hydrolase
CNH35_RS08090	COG0667	Aldo Keto reductase
CNH35_RS08100	COG4221	oxidoreductase activity
CNH35_RS08115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CNH35_RS08125	COG0366	Alpha amylase catalytic
CNH35_RS08130	COG1609	Transcriptional regulator
CNH35_RS08150	COG2195	Cleaves the N-terminal amino acid of tripeptides
CNH35_RS08160	COG4129	membrane
CNH35_RS08170	COG0508	dehydrogenase complex catalyzes the overall conversion of
CNH35_RS08175	COG0022	dehydrogenase e1 component
CNH35_RS08180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CNH35_RS08185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CNH35_RS08190	COG0497	DNA recombination
CNH35_RS08220	COG1302	Protein conserved in bacteria
CNH35_RS08225	COG0439	Biotin carboxylase
CNH35_RS08230	COG0511	ligase activity, forming carbon-carbon bonds
CNH35_RS08240	COG0006	proline dipeptidase activity
CNH35_RS08255	COG0095	Lipoate-protein ligase
CNH35_RS08260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CNH35_RS08280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CNH35_RS08305	COG4537	Required for transformation and DNA binding
CNH35_RS08310	COG1459	type II secretion system
CNH35_RS08315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CNH35_RS08320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNH35_RS08325	COG0011	TIGRFAM Protein of
CNH35_RS08330	COG1940	carbohydrate kinase activity
CNH35_RS08335	COG4483	Protein conserved in bacteria
CNH35_RS08345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CNH35_RS08365	COG0735	belongs to the Fur family
CNH35_RS08370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CNH35_RS08375	COG1121	(ABC) transporter
CNH35_RS08385	COG0513	Belongs to the DEAD box helicase family
CNH35_RS08395	COG2384	SAM-dependent methyltransferase
CNH35_RS08400	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CNH35_RS08415	COG0517	IMP dehydrogenase activity
CNH35_RS08435	COG0295	cytidine deaminase activity
CNH35_RS08450	COG1702	phosphate starvation-inducible protein PhoH
CNH35_RS08465	COG1030	water channel activity
CNH35_RS08475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNH35_RS08480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CNH35_RS08510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CNH35_RS08530	COG1466	dna polymerase III delta subunit
CNH35_RS08535	COG2333	competence protein COMEC
CNH35_RS08535	COG0658	competence protein
CNH35_RS08540	COG2131	deaminase
CNH35_RS08550	COG2226	methyltransferase
CNH35_RS08555	COG0799	negative regulation of ribosome biogenesis
CNH35_RS08560	COG1713	HD superfamily hydrolase involved in NAD metabolism
CNH35_RS08570	COG1534	Rna-binding protein
CNH35_RS08580	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CNH35_RS08585	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CNH35_RS08605	COG3177	Filamentation induced by cAMP protein fic
CNH35_RS08610	COG1914	H( )-stimulated, divalent metal cation uptake system
CNH35_RS08620	COG0439	Biotin carboxylase
CNH35_RS08625	COG0511	ligase activity, forming carbon-carbon bonds
CNH35_RS08630	COG1984	allophanate hydrolase subunit 2
CNH35_RS08635	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CNH35_RS08685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CNH35_RS08700	COG1104	cysteine desulfurase activity
CNH35_RS08705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CNH35_RS08720	COG1959	2 iron, 2 sulfur cluster binding
CNH35_RS08725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CNH35_RS08730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CNH35_RS08775	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CNH35_RS08775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CNH35_RS08780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNH35_RS08780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CNH35_RS08785	COG1862	Preprotein translocase
CNH35_RS08825	COG2868	ribosomal protein
CNH35_RS08870	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CNH35_RS08880	COG0285	dihydrofolate synthase activity
CNH35_RS08890	COG2818	Glycosylase
CNH35_RS08910	COG0113	porphobilinogen synthase activity
CNH35_RS08925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CNH35_RS08960	COG4112	unkown
CNH35_RS08985	COG0833	amino acid
CNH35_RS09000	COG1484	DNA-dependent DNA replication
CNH35_RS09025	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CNH35_RS09030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CNH35_RS09030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CNH35_RS09040	COG5002	protein histidine kinase activity
CNH35_RS09045	COG0745	RESPONSE REGULATOR receiver
CNH35_RS09060	COG0372	Belongs to the citrate synthase family
CNH35_RS09065	COG1113	amino acid transport
CNH35_RS09095	COG0281	malic enzyme
CNH35_RS09105	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CNH35_RS09115	COG4109	DRTGG domain
CNH35_RS09155	COG0827	DNA restriction-modification system
CNH35_RS09175	COG1104	cysteine desulfurase activity
CNH35_RS09190	COG1956	GAF domain-containing protein
CNH35_RS09210	COG0584	glycerophosphoryl diester phosphodiesterase
CNH35_RS09215	COG1764	response to oxidative stress
CNH35_RS09220	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CNH35_RS09225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNH35_RS09240	COG1263	PTS System
CNH35_RS09240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNH35_RS09245	COG0204	Acyl-transferase
CNH35_RS09250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CNH35_RS09285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CNH35_RS09290	COG0454	-acetyltransferase
CNH35_RS09310	COG1605	Chorismate mutase
CNH35_RS09310	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CNH35_RS09335	COG1674	ftsk spoiiie
CNH35_RS09340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNH35_RS09350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CNH35_RS09355	COG1363	Peptidase, m42
CNH35_RS09365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CNH35_RS09375	COG0510	thiamine kinase activity
CNH35_RS09400	COG1187	pseudouridine synthase activity
CNH35_RS09405	COG2244	polysaccharide biosynthetic process
CNH35_RS09410	COG2081	HI0933 family
CNH35_RS09430	COG2814	Major facilitator Superfamily
CNH35_RS09435	COG1242	4 iron, 4 sulfur cluster binding
CNH35_RS09440	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CNH35_RS09445	COG1846	Transcriptional regulator
CNH35_RS09455	COG2267	carboxylic ester hydrolase activity
CNH35_RS09490	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CNH35_RS09490	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CNH35_RS09515	COG4193	domain, Protein
CNH35_RS09515	COG5632	N-Acetylmuramoyl-L-alanine amidase
CNH35_RS09515	COG3266	domain, Protein
CNH35_RS09545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CNH35_RS09555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNH35_RS09560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNH35_RS09570	COG0656	L-ascorbic acid biosynthetic process
CNH35_RS09590	COG1943	Transposase
CNH35_RS09595	COG1506	peptidase
CNH35_RS09720	COG3591	Belongs to the peptidase S1B family
CNH35_RS09925	COG1131	(ABC) transporter
CNH35_RS09930	COG0537	adenosine 5'-monophosphoramidase activity
CNH35_RS09965	COG0420	3'-5' exonuclease activity
CNH35_RS09995	COG2197	response regulator
CNH35_RS10000	COG2203	Gaf domain
CNH35_RS10000	COG4585	Histidine kinase
CNH35_RS10005	COG0564	pseudouridine synthase activity
CNH35_RS10045	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CNH35_RS10050	COG1126	abc transporter atp-binding protein
CNH35_RS10055	COG0765	amino acid transport
CNH35_RS10235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNH35_RS10240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CNH35_RS10250	COG4129	membrane
CNH35_RS10275	COG1988	membrane-bound metal-dependent
CNH35_RS10290	COG1134	teichoic acid transport
CNH35_RS10290	COG1388	LysM domain
CNH35_RS10330	COG0860	N-Acetylmuramoyl-L-alanine amidase
CNH35_RS10330	COG1388	LysM domain
CNH35_RS10460	COG1783	phage Terminase large subunit
CNH35_RS10560	COG1484	DNA-dependent DNA replication
CNH35_RS10635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNH35_RS10650	COG4974	Belongs to the 'phage' integrase family
CNH35_RS10655	COG0535	radical SAM domain protein
CNH35_RS10660	COG1607	acyl-coa hydrolase
CNH35_RS10665	COG2309	aminopeptidase activity
CNH35_RS10685	COG1295	ribonuclease BN
CNH35_RS10820	COG4851	CamS sex pheromone cAM373 precursor
CNH35_RS10830	COG0210	DNA helicase
CNH35_RS10835	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CNH35_RS10840	COG4496	protein, YerC YecD
CNH35_RS10880	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CNH35_RS10890	COG0077	Prephenate dehydratase
CNH35_RS10900	COG0471	metal ion transport
CNH35_RS10910	COG1335	isochorismatase
CNH35_RS10925	COG1012	belongs to the aldehyde dehydrogenase family
CNH35_RS10980	COG1131	(ABC) transporter
CNH35_RS10995	COG1725	Transcriptional regulator
CNH35_RS11025	COG3568	Endonuclease Exonuclease Phosphatase
CNH35_RS11055	COG1388	LysM domain
CNH35_RS11055	COG0860	N-Acetylmuramoyl-L-alanine amidase
CNH35_RS11070	COG1388	LysM domain
CNH35_RS11070	COG5632	N-Acetylmuramoyl-L-alanine amidase
CNH35_RS11125	COG0739	heme binding
CNH35_RS11175	COG0740	serine-type endopeptidase activity
CNH35_RS11350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNH35_RS11400	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CNH35_RS11405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CNH35_RS11410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CNH35_RS11430	COG3728	DNA packaging
CNH35_RS11430	COG5484	DNA packaging
CNH35_RS11505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNH35_RS11510	COG1621	beta-fructofuranosidase activity
CNH35_RS11515	COG1609	Transcriptional regulator
CNH35_RS11520	COG0004	ammonium transporteR
CNH35_RS11525	COG0425	Belongs to the sulfur carrier protein TusA family
CNH35_RS11530	COG2391	methyltransferase activity
CNH35_RS11540	COG0488	(ABC) transporter
CNH35_RS11550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CNH35_RS11560	COG0456	acetyltransferase
CNH35_RS11565	COG1214	PFAM Peptidase M22, glycoprotease
CNH35_RS11570	COG0802	atpase or kinase
CNH35_RS11585	COG0028	Belongs to the TPP enzyme family
CNH35_RS11660	COG2183	response to ionizing radiation
CNH35_RS11665	COG1191	sigma factor activity
CNH35_RS11675	COG1366	Belongs to the anti-sigma-factor antagonist family
CNH35_RS11680	COG2208	phosphoserine phosphatase activity
CNH35_RS11700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CNH35_RS11715	COG3428	Bacterial PH domain
CNH35_RS11745	COG2205	protein histidine kinase activity
CNH35_RS11750	COG0745	RESPONSE REGULATOR receiver
CNH35_RS11760	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CNH35_RS11770	COG0772	Belongs to the SEDS family
CNH35_RS11785	COG1937	Protein conserved in bacteria
CNH35_RS11795	COG1418	mRNA catabolic process
CNH35_RS11845	COG0629	single-stranded DNA binding
CNH35_RS11920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CNH35_RS11945	COG0009	L-threonylcarbamoyladenylate synthase
CNH35_RS11950	COG2890	protein-(glutamine-N5) methyltransferase activity
CNH35_RS11975	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CNH35_RS12015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNH35_RS12065	COG0813	purine-nucleoside phosphorylase activity
CNH35_RS12070	COG0783	Belongs to the Dps family
CNH35_RS12090	COG1482	cell wall glycoprotein biosynthetic process
CNH35_RS12095	COG0702	epimerase
CNH35_RS12100	COG0640	Transcriptional regulator
CNH35_RS12135	COG0561	phosphatase activity
CNH35_RS12140	COG1119	ATPase activity
CNH35_RS12155	COG3711	transcriptional antiterminator
CNH35_RS12185	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CNH35_RS12260	COG0489	protein tyrosine kinase activity
CNH35_RS12265	COG2814	Major facilitator Superfamily
CNH35_RS12280	COG1272	protein, Hemolysin III
CNH35_RS12290	COG1988	membrane-bound metal-dependent
CNH35_RS12305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNH35_RS12310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CNH35_RS12315	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CNH35_RS12325	COG3457	Alanine racemase
CNH35_RS12330	COG4264	IucA IucC family
CNH35_RS12335	COG2814	Major facilitator Superfamily
CNH35_RS12365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CNH35_RS12375	COG2130	NADP-dependent
CNH35_RS12415	COG1349	DNA-binding transcription factor activity
CNH35_RS12420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNH35_RS12440	COG0656	L-ascorbic acid biosynthetic process
CNH35_RS12445	COG0789	Transcriptional regulator
CNH35_RS12455	COG5492	domain, Protein
CNH35_RS12475	COG3527	Alpha-acetolactate decarboxylase
CNH35_RS12480	COG0028	Belongs to the TPP enzyme family
CNH35_RS12500	COG0542	response to heat
CNH35_RS12585	COG0201	protein transport
CNH35_RS12700	COG2252	PERMEase
CNH35_RS12745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CNH35_RS12820	COG1763	Mo-molybdopterin cofactor biosynthetic process
CNH35_RS12840	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CNH35_RS12845	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CNH35_RS12850	COG4149	molybdate abc transporter
CNH35_RS12855	COG0725	ABC transporter, periplasmic molybdate-binding protein
CNH35_RS12870	COG1268	BioY protein
CNH35_RS12885	COG1960	acyl-CoA dehydrogenase activity
CNH35_RS12890	COG4413	Urea transporter
CNH35_RS12955	COG3942	CHAP domain
CNH35_RS12965	COG1757	Na H antiporter
CNH35_RS13055	COG1113	amino acid transport
CNH35_RS13075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNH35_RS13080	COG0385	Bile acid
CNH35_RS13090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNH35_RS13090	COG1263	PTS System
CNH35_RS13095	COG1737	Transcriptional regulator
CNH35_RS13115	COG1028	Short-chain dehydrogenase reductase Sdr
CNH35_RS13120	COG1473	amidohydrolase
CNH35_RS13135	COG0583	DNA-binding transcription factor activity
CNH35_RS13160	COG2258	MOSC domain
CNH35_RS13180	COG1668	transmembrane transport
CNH35_RS13185	COG4152	abc transporter atp-binding protein
CNH35_RS13190	COG3152	Membrane
CNH35_RS13205	COG0786	glutamate:sodium symporter activity
CNH35_RS13215	COG0598	Magnesium transport protein CorA
CNH35_RS13230	COG0657	acetylesterase activity
CNH35_RS13240	COG2814	Major facilitator Superfamily
CNH35_RS13245	COG1566	PFAM secretion protein HlyD family protein
CNH35_RS13255	COG2814	Major facilitator Superfamily
CNH35_RS13325	COG1620	l-lactate permease
CNH35_RS13345	COG0604	alcohol dehydrogenase
CNH35_RS13350	COG0456	acetyltransferase
CNH35_RS13375	COG1511	domain protein
CNH35_RS13390	COG1263	PTS System
CNH35_RS13390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNH35_RS13405	COG3871	stress protein (general stress protein 26)
CNH35_RS13415	COG1301	dicarboxylic acid transport
CNH35_RS13450	COG0789	Transcriptional regulator
CNH35_RS13470	COG2181	nitrate reductase activity
CNH35_RS13480	COG1140	nitrate reductase beta subunit
CNH35_RS13485	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CNH35_RS13495	COG2146	nitrite reductase [NAD(P)H] activity
CNH35_RS13500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CNH35_RS13510	COG0454	-acetyltransferase
CNH35_RS13515	COG2116	formate transmembrane transporter activity
CNH35_RS13530	COG0803	Belongs to the bacterial solute-binding protein 9 family
CNH35_RS13530	COG3443	Belongs to the bacterial solute-binding protein 9 family
CNH35_RS13570	COG1126	abc transporter atp-binding protein
CNH35_RS13575	COG0765	amino acid transport
CNH35_RS13580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNH35_RS13585	COG2814	Major facilitator Superfamily
CNH35_RS13605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CNH35_RS13655	COG0156	8-amino-7-oxononanoate synthase activity
CNH35_RS13665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CNH35_RS13670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CNH35_RS13685	COG1132	(ABC) transporter
CNH35_RS13710	COG1929	Belongs to the glycerate kinase type-1 family
CNH35_RS13720	COG2814	Major facilitator Superfamily
CNH35_RS13740	COG1113	amino acid transport
CNH35_RS13755	COG0531	amino acid
CNH35_RS13780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CNH35_RS13790	COG1174	glycine betaine transport
CNH35_RS13800	COG1174	glycine betaine transport
CNH35_RS13820	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CNH35_RS13830	COG0531	amino acid
CNH35_RS13835	COG2272	Belongs to the type-B carboxylesterase lipase family
CNH35_RS13840	COG2814	Major facilitator Superfamily
CNH35_RS13845	COG0390	transport system, permease component
CNH35_RS13850	COG4619	ABC transporter
CNH35_RS13855	COG1363	Peptidase, m42
CNH35_RS13875	COG4808	Protein conserved in bacteria
CNH35_RS13880	COG0069	glutamate synthase activity
CNH35_RS13895	COG1124	(ABC) transporter
CNH35_RS13900	COG0444	Belongs to the ABC transporter superfamily
CNH35_RS13905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNH35_RS13910	COG0601	transmembrane transport
CNH35_RS13915	COG0747	negative chemotaxis
CNH35_RS13945	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CNH35_RS13950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CNH35_RS14040	COG0494	nUDIX hydrolase
CNH35_RS14075	COG3583	domain protein
CNH35_RS14080	COG1846	Transcriptional regulator
CNH35_RS14120	COG1070	Carbohydrate kinase
CNH35_RS14125	COG1802	Transcriptional regulator
CNH35_RS14130	COG0789	Transcriptional regulator
CNH35_RS14135	COG2357	RelA SpoT domain protein
CNH35_RS14140	COG4876	unkown
CNH35_RS14150	COG2271	Major facilitator Superfamily
CNH35_RS14155	COG0586	Pfam SNARE associated Golgi protein
CNH35_RS14165	COG2814	Major facilitator Superfamily
CNH35_RS14170	COG1846	Transcriptional regulator
CNH35_RS14185	COG1131	(ABC) transporter
CNH35_RS14205	COG0400	carboxylic ester hydrolase activity
CNH35_RS14210	COG0346	lactoylglutathione lyase activity
CNH35_RS14215	COG1846	Transcriptional regulator
CNH35_RS14225	COG2514	catechol 2,3-dioxygenase activity
CNH35_RS14240	COG0561	phosphatase activity
CNH35_RS14245	COG1131	(ABC) transporter
CNH35_RS14255	COG3764	Sortase (surface protein transpeptidase)
CNH35_RS14275	COG1760	l-serine dehydratase
CNH35_RS14280	COG1760	l-serine dehydratase
CNH35_RS14295	COG0697	spore germination
CNH35_RS14300	COG0657	acetylesterase activity
CNH35_RS14320	COG0028	Belongs to the TPP enzyme family
CNH35_RS14325	COG1346	cytolysis
CNH35_RS14335	COG0583	DNA-binding transcription factor activity
CNH35_RS14345	COG3942	CHAP domain
CNH35_RS14370	COG3425	synthase
CNH35_RS14375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CNH35_RS14380	COG0542	response to heat
CNH35_RS14400	COG2409	Drug exporters of the RND superfamily
CNH35_RS14430	COG2217	Heavy metal translocating P-type atpase
CNH35_RS14445	COG0436	Aminotransferase
CNH35_RS14480	COG2755	lipolytic protein G-D-S-L family
CNH35_RS14480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CNH35_RS14595	COG0167	dihydroorotate dehydrogenase activity
CNH35_RS14645	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CNH35_RS14650	COG3527	Alpha-acetolactate decarboxylase
CNH35_RS14665	COG0531	amino acid
CNH35_RS14695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CNH35_RS14725	COG1510	regulation of RNA biosynthetic process
CNH35_RS14735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CNH35_RS14760	COG2851	Citrate transporter
CNH35_RS14775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CNH35_RS14785	COG0386	Belongs to the glutathione peroxidase family
CNH35_RS14810	COG1136	(ABC) transporter
CNH35_RS14815	COG2205	protein histidine kinase activity
CNH35_RS14820	COG0745	RESPONSE REGULATOR receiver
CNH35_RS14830	COG1785	Belongs to the alkaline phosphatase family
CNH35_RS14840	COG1846	Transcriptional regulator
CNH35_RS14850	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CNH35_RS14850	COG4932	domain protein
CNH35_RS14875	COG2235	arginine
CNH35_RS14905	COG3711	transcriptional antiterminator
CNH35_RS14905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNH35_RS14910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNH35_RS14910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CNH35_RS14910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CNH35_RS14915	COG1482	cell wall glycoprotein biosynthetic process
CNH35_RS14925	COG3942	CHAP domain
CNH35_RS14925	COG1705	Flagellar rod assembly protein muramidase FlgJ
CNH35_RS14930	COG1535	isochorismatase
CNH35_RS14930	COG3433	isochorismatase activity
CNH35_RS14945	COG0438	transferase activity, transferring glycosyl groups
CNH35_RS14960	COG1073	alpha beta
CNH35_RS14970	COG0201	protein transport
CNH35_RS14980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CNH35_RS15000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CNH35_RS15030	COG1309	transcriptional regulator
CNH35_RS15035	COG1215	transferase activity, transferring glycosyl groups
CNH35_RS15045	COG0726	polysaccharide deacetylase
CNH35_RS15050	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CNH35_RS15060	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CNH35_RS15095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNH35_RS15180	COG0471	metal ion transport
CNH35_RS15185	COG2962	Rard protein
CNH35_RS15195	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
CNH35_RS15210	COG1136	(ABC) transporter
CNH35_RS15215	COG0577	efflux transmembrane transporter activity
CNH35_RS15245	COG1278	Cold shock
CNH35_RS15265	COG1475	DNA binding