locus-tag	class	description
CRN29_RS00010	COG2814	Major facilitator Superfamily
CRN29_RS00015	COG0583	DNA-binding transcription factor activity
CRN29_RS00020	COG2318	DinB family
CRN29_RS00025	COG2311	Membrane
CRN29_RS00030	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
CRN29_RS00040	COG0471	metal ion transport
CRN29_RS00055	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CRN29_RS00060	COG1054	Belongs to the UPF0176 family
CRN29_RS00065	COG3386	PFAM SMP-30 Gluconolaconase
CRN29_RS00070	COG2353	YceI-like domain
CRN29_RS00080	COG0579	oxidoreductase
CRN29_RS00100	COG0693	protein deglycase activity
CRN29_RS00110	COG1686	Belongs to the peptidase S11 family
CRN29_RS00145	COG0726	polysaccharide deacetylase
CRN29_RS00175	COG2814	Major facilitator Superfamily
CRN29_RS00185	COG0737	Belongs to the 5'-nucleotidase family
CRN29_RS00200	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CRN29_RS00205	COG3639	organic phosphonate transmembrane transporter activity
CRN29_RS00215	COG0702	epimerase
CRN29_RS00230	COG0201	protein transport
CRN29_RS00240	COG1073	alpha beta
CRN29_RS00250	COG0653	protein targeting
CRN29_RS00260	COG0438	transferase activity, transferring glycosyl groups
CRN29_RS00290	COG2814	Major facilitator Superfamily
CRN29_RS00295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CRN29_RS00300	COG0604	alcohol dehydrogenase
CRN29_RS00315	COG2113	Glycine betaine
CRN29_RS00330	COG0583	DNA-binding transcription factor activity
CRN29_RS00335	COG3842	ATPase activity
CRN29_RS00340	COG1840	ABC-type Fe3 transport system, periplasmic component
CRN29_RS00350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CRN29_RS00355	COG1764	response to oxidative stress
CRN29_RS00370	COG1705	Flagellar rod assembly protein muramidase FlgJ
CRN29_RS00370	COG3942	CHAP domain
CRN29_RS00370	COG3942	CHAP domain
CRN29_RS00370	COG1705	Flagellar rod assembly protein muramidase FlgJ
CRN29_RS00380	COG1482	cell wall glycoprotein biosynthetic process
CRN29_RS00385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRN29_RS00385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN29_RS00385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRN29_RS00390	COG3711	transcriptional antiterminator
CRN29_RS00390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN29_RS00395	COG2814	Major facilitator Superfamily
CRN29_RS00400	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CRN29_RS00440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRN29_RS00480	COG2235	arginine
CRN29_RS00485	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CRN29_RS00500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CRN29_RS00515	COG2843	Capsule synthesis protein
CRN29_RS00525	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CRN29_RS00530	COG3961	Belongs to the TPP enzyme family
CRN29_RS00535	COG1846	Transcriptional regulator
CRN29_RS00550	COG4195	phage-related replication protein
CRN29_RS00560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CRN29_RS00570	COG0702	epimerase
CRN29_RS00575	COG1785	Belongs to the alkaline phosphatase family
CRN29_RS00580	COG0745	RESPONSE REGULATOR receiver
CRN29_RS00585	COG2205	protein histidine kinase activity
CRN29_RS00590	COG1136	(ABC) transporter
CRN29_RS00605	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CRN29_RS00630	COG0386	Belongs to the glutathione peroxidase family
CRN29_RS00635	COG0175	sulfate reduction
CRN29_RS00640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CRN29_RS00645	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CRN29_RS00660	COG0730	response to heat
CRN29_RS00665	COG2046	Belongs to the sulfate adenylyltransferase family
CRN29_RS00670	COG0529	Catalyzes the synthesis of activated sulfate
CRN29_RS00675	COG2851	Citrate transporter
CRN29_RS00690	COG1328	CTP reductase activity
CRN29_RS00695	COG0602	queuosine metabolic process
CRN29_RS00700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CRN29_RS00710	COG1510	regulation of RNA biosynthetic process
CRN29_RS00715	COG1012	belongs to the aldehyde dehydrogenase family
CRN29_RS00720	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CRN29_RS00725	COG1473	amidohydrolase
CRN29_RS00750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CRN29_RS00755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CRN29_RS00755	COG0574	Belongs to the PEP-utilizing enzyme family
CRN29_RS00760	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CRN29_RS00765	COG0579	oxidoreductase
CRN29_RS00785	COG3588	fructose-bisphosphate aldolase
CRN29_RS00790	COG0446	pyridine nucleotide-disulphide oxidoreductase
CRN29_RS00815	COG0531	amino acid
CRN29_RS00825	COG0583	DNA-binding transcription factor activity
CRN29_RS00830	COG0039	L-malate dehydrogenase activity
CRN29_RS00835	COG0028	Belongs to the TPP enzyme family
CRN29_RS00840	COG3527	Alpha-acetolactate decarboxylase
CRN29_RS00850	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CRN29_RS00855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CRN29_RS00870	COG4640	response to antibiotic
CRN29_RS00905	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CRN29_RS00915	COG0167	dihydroorotate dehydrogenase activity
CRN29_RS00920	COG3001	Fructosamine kinase
CRN29_RS00935	COG0596	Alpha beta hydrolase
CRN29_RS00945	COG1028	Short-chain dehydrogenase reductase Sdr
CRN29_RS00970	COG1113	amino acid transport
CRN29_RS00985	COG2326	polyphosphate kinase activity
CRN29_RS00990	COG0741	lytic transglycosylase activity
CRN29_RS01025	COG0436	Aminotransferase
CRN29_RS01040	COG2608	mercury ion transmembrane transporter activity
CRN29_RS01045	COG2217	Heavy metal translocating P-type atpase
CRN29_RS01055	COG1028	Short-chain dehydrogenase reductase Sdr
CRN29_RS01065	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CRN29_RS01070	COG1012	belongs to the aldehyde dehydrogenase family
CRN29_RS01105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CRN29_RS01110	COG3425	synthase
CRN29_RS01130	COG0583	DNA-binding transcription factor activity
CRN29_RS01135	COG1380	Effector of murein hydrolase LrgA
CRN29_RS01140	COG1346	cytolysis
CRN29_RS01145	COG0028	Belongs to the TPP enzyme family
CRN29_RS01155	COG1266	CAAX protease self-immunity
CRN29_RS01170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRN29_RS01175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRN29_RS01185	COG0697	spore germination
CRN29_RS01190	COG1917	Cupin 2, conserved barrel domain protein
CRN29_RS01190	COG2207	Transcriptional regulator
CRN29_RS01200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CRN29_RS01210	COG2843	Capsule synthesis protein
CRN29_RS01225	COG4975	Glucose uptake
CRN29_RS01230	COG1869	D-ribose catabolic process
CRN29_RS01240	COG1070	Carbohydrate kinase
CRN29_RS01255	COG1760	l-serine dehydratase
CRN29_RS01260	COG1760	l-serine dehydratase
CRN29_RS01270	COG1247	-acetyltransferase
CRN29_RS01275	COG3764	Sortase (surface protein transpeptidase)
CRN29_RS01280	COG0561	phosphatase activity
CRN29_RS01290	COG0778	Nitroreductase
CRN29_RS01295	COG1012	belongs to the aldehyde dehydrogenase family
CRN29_RS01300	COG2514	catechol 2,3-dioxygenase activity
CRN29_RS01315	COG1012	belongs to the aldehyde dehydrogenase family
CRN29_RS01320	COG3949	Membrane
CRN29_RS01330	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CRN29_RS01335	COG0586	Pfam SNARE associated Golgi protein
CRN29_RS01345	COG2022	thiamine diphosphate biosynthetic process
CRN29_RS01355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRN29_RS01365	COG2271	Major facilitator Superfamily
CRN29_RS01380	COG4876	unkown
CRN29_RS01385	COG2357	RelA SpoT domain protein
CRN29_RS01400	COG1802	Transcriptional regulator
CRN29_RS01405	COG1070	Carbohydrate kinase
CRN29_RS01410	COG2610	gluconate transmembrane transporter activity
CRN29_RS01415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CRN29_RS01420	COG1216	Glycosyl transferase, family 2
CRN29_RS01435	COG4221	oxidoreductase activity
CRN29_RS01440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRN29_RS01445	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CRN29_RS01450	COG0248	Ppx GppA phosphatase
CRN29_RS01455	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CRN29_RS01460	COG1028	Short-chain dehydrogenase reductase Sdr
CRN29_RS01470	COG1363	Peptidase, m42
CRN29_RS01475	COG4808	Protein conserved in bacteria
CRN29_RS01480	COG0069	glutamate synthase activity
CRN29_RS01495	COG4619	ABC transporter
CRN29_RS01500	COG0390	transport system, permease component
CRN29_RS01505	COG2814	Major facilitator Superfamily
CRN29_RS01510	COG2272	Belongs to the type-B carboxylesterase lipase family
CRN29_RS01515	COG0531	amino acid
CRN29_RS01520	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CRN29_RS01525	COG1063	alcohol dehydrogenase
CRN29_RS01545	COG1174	glycine betaine transport
CRN29_RS01550	COG1346	cytolysis
CRN29_RS01555	COG1380	Effector of murein hydrolase LrgA
CRN29_RS01565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CRN29_RS01580	COG0706	membrane insertase activity
CRN29_RS01590	COG0531	amino acid
CRN29_RS01600	COG1113	amino acid transport
CRN29_RS01620	COG2814	Major facilitator Superfamily
CRN29_RS01630	COG1929	Belongs to the glycerate kinase type-1 family
CRN29_RS01645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CRN29_RS01650	COG0741	lytic transglycosylase activity
CRN29_RS01655	COG0588	phosphoglycerate mutase activity
CRN29_RS01665	COG2814	Major facilitator Superfamily
CRN29_RS01670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRN29_RS01675	COG0765	amino acid transport
CRN29_RS01680	COG1126	abc transporter atp-binding protein
CRN29_RS01690	COG2348	transferase activity, transferring amino-acyl groups
CRN29_RS01725	COG0454	-acetyltransferase
CRN29_RS01730	COG0747	negative chemotaxis
CRN29_RS01740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CRN29_RS01745	COG2146	nitrite reductase [NAD(P)H] activity
CRN29_RS01755	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CRN29_RS01760	COG1140	nitrate reductase beta subunit
CRN29_RS01770	COG2181	nitrate reductase activity
CRN29_RS01780	COG4585	Histidine kinase
CRN29_RS01785	COG2197	response regulator
CRN29_RS01790	COG2223	nitrite transmembrane transporter activity
CRN29_RS01805	COG0778	Nitroreductase
CRN29_RS01825	COG3871	stress protein (general stress protein 26)
CRN29_RS01830	COG2207	Transcriptional regulator
CRN29_RS01830	COG4753	response regulator
CRN29_RS01840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN29_RS01840	COG1263	PTS System
CRN29_RS01875	COG0492	ferredoxin-NADP+ reductase activity
CRN29_RS01885	COG0604	alcohol dehydrogenase
CRN29_RS01890	COG2822	iron ion transport
CRN29_RS01895	COG2837	iron assimilation
CRN29_RS01900	COG0672	)-iron permease
CRN29_RS01905	COG0805	protein transport
CRN29_RS01910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CRN29_RS01920	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CRN29_RS01920	COG0463	Glycosyl transferase, family 2
CRN29_RS01930	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CRN29_RS01935	COG1620	l-lactate permease
CRN29_RS01945	COG0579	oxidoreductase
CRN29_RS01950	COG5002	protein histidine kinase activity
CRN29_RS01950	COG3850	Histidine kinase
CRN29_RS01955	COG0745	RESPONSE REGULATOR receiver
CRN29_RS01960	COG0577	efflux transmembrane transporter activity
CRN29_RS01965	COG1136	(ABC) transporter
CRN29_RS01980	COG4640	response to antibiotic
CRN29_RS01985	COG2814	Major facilitator Superfamily
CRN29_RS01995	COG1566	PFAM secretion protein HlyD family protein
CRN29_RS02000	COG2814	Major facilitator Superfamily
CRN29_RS02025	COG0598	Magnesium transport protein CorA
CRN29_RS02030	COG1304	FMN binding
CRN29_RS02035	COG0786	glutamate:sodium symporter activity
CRN29_RS02055	COG2094	Belongs to the DNA glycosylase MPG family
CRN29_RS02060	COG3152	Membrane
CRN29_RS02075	COG1069	ribulokinase activity
CRN29_RS02080	COG4152	abc transporter atp-binding protein
CRN29_RS02085	COG1668	transmembrane transport
CRN29_RS02090	COG1742	UPF0060 membrane protein
CRN29_RS02100	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CRN29_RS02105	COG1266	CAAX protease self-immunity
CRN29_RS02110	COG0010	Belongs to the arginase family
CRN29_RS02115	COG0583	DNA-binding transcription factor activity
CRN29_RS02130	COG0659	secondary active sulfate transmembrane transporter activity
CRN29_RS02135	COG1473	amidohydrolase
CRN29_RS02140	COG1028	Short-chain dehydrogenase reductase Sdr
CRN29_RS02160	COG1737	Transcriptional regulator
CRN29_RS02165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN29_RS02165	COG1263	PTS System
CRN29_RS02175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CRN29_RS02195	COG1113	amino acid transport
CRN29_RS02205	COG1263	PTS System
CRN29_RS02205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN29_RS02210	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CRN29_RS02240	COG1316	TRANSCRIPTIONal
CRN29_RS02270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRN29_RS02275	COG2076	Multidrug Resistance protein
CRN29_RS02280	COG2076	Multidrug Resistance protein
CRN29_RS02285	COG3942	CHAP domain
CRN29_RS02300	COG1757	Na H antiporter
CRN29_RS02305	COG3942	CHAP domain
CRN29_RS02330	COG0829	nickel cation binding
CRN29_RS02345	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CRN29_RS02350	COG0804	urea catabolic process
CRN29_RS02360	COG0831	urea catabolic process
CRN29_RS02365	COG4413	Urea transporter
CRN29_RS02370	COG1960	acyl-CoA dehydrogenase activity
CRN29_RS02375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CRN29_RS02385	COG1268	BioY protein
CRN29_RS02400	COG0725	ABC transporter, periplasmic molybdate-binding protein
CRN29_RS02405	COG4149	molybdate abc transporter
CRN29_RS02410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CRN29_RS02415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CRN29_RS02420	COG0521	Mo-molybdopterin cofactor biosynthetic process
CRN29_RS02425	COG0315	cyclic pyranopterin monophosphate synthase activity
CRN29_RS02430	COG0303	'Molybdopterin
CRN29_RS02435	COG1763	Mo-molybdopterin cofactor biosynthetic process
CRN29_RS02450	COG0746	molybdenum cofactor guanylyltransferase activity
CRN29_RS02455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CRN29_RS02465	COG2814	Major facilitator Superfamily
CRN29_RS02485	COG2348	transferase activity, transferring amino-acyl groups
CRN29_RS02490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CRN29_RS02515	COG4975	Glucose uptake
CRN29_RS02525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CRN29_RS02525	COG0551	DNA topoisomerase type I activity
CRN29_RS02530	COG2252	PERMEase
CRN29_RS02545	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CRN29_RS02550	COG0088	Forms part of the polypeptide exit tunnel
CRN29_RS02555	COG0089	rRNA binding
CRN29_RS02560	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CRN29_RS02565	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CRN29_RS02575	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CRN29_RS02580	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CRN29_RS02590	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CRN29_RS02595	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CRN29_RS02600	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CRN29_RS02605	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CRN29_RS02610	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CRN29_RS02615	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CRN29_RS02620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CRN29_RS02625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CRN29_RS02630	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CRN29_RS02635	COG1841	ribosomal large subunit assembly
CRN29_RS02640	COG0200	Binds to the 23S rRNA
CRN29_RS02645	COG0201	protein transport
CRN29_RS02650	COG0563	adenylate kinase activity
CRN29_RS02655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CRN29_RS02660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CRN29_RS02665	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CRN29_RS02675	COG0202	RNA polymerase activity
CRN29_RS02680	COG0203	ribosomal protein L17
CRN29_RS02685	COG1122	ATPase activity
CRN29_RS02690	COG1122	ATPase activity
CRN29_RS02700	COG0101	tRNA pseudouridine synthase activity
CRN29_RS02705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CRN29_RS02715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CRN29_RS02720	COG1349	DNA-binding transcription factor activity
CRN29_RS02725	COG0698	ribose 5-phosphate isomerase
CRN29_RS02765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN29_RS02770	COG2130	NADP-dependent
CRN29_RS02775	COG0604	alcohol dehydrogenase
CRN29_RS02780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CRN29_RS02795	COG1302	Protein conserved in bacteria
CRN29_RS02800	COG4264	IucA IucC family
CRN29_RS02805	COG2814	Major facilitator Superfamily
CRN29_RS02810	COG4264	IucA IucC family
CRN29_RS02815	COG3457	Alanine racemase
CRN29_RS02820	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CRN29_RS02825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN29_RS02830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN29_RS02835	COG3314	Sporulation integral membrane protein YlbJ
CRN29_RS02840	COG2329	Antibiotic biosynthesis monooxygenase
CRN29_RS02850	COG1988	membrane-bound metal-dependent
CRN29_RS02855	COG4284	Utp--glucose-1-phosphate uridylyltransferase
CRN29_RS02860	COG1272	protein, Hemolysin III
CRN29_RS02875	COG2814	Major facilitator Superfamily
CRN29_RS02880	COG0489	protein tyrosine kinase activity
CRN29_RS02935	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CRN29_RS02945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CRN29_RS02960	COG3711	transcriptional antiterminator
CRN29_RS02970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CRN29_RS02975	COG0561	phosphatase activity
CRN29_RS02995	COG0640	Transcriptional regulator
CRN29_RS03000	COG0702	epimerase
CRN29_RS03005	COG1482	cell wall glycoprotein biosynthetic process
CRN29_RS03025	COG0783	Belongs to the Dps family
CRN29_RS03030	COG0813	purine-nucleoside phosphorylase activity
CRN29_RS03035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CRN29_RS03040	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CRN29_RS03045	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CRN29_RS03060	COG1854	S-ribosylhomocysteine lyase activity
CRN29_RS03080	COG5146	pantothenate kinase activity
CRN29_RS03090	COG3343	RNA polymerase activity
CRN29_RS03095	COG0504	CTP synthase activity
CRN29_RS03105	COG0191	fructose-bisphosphate aldolase activity
CRN29_RS03110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CRN29_RS03120	COG1012	belongs to the aldehyde dehydrogenase family
CRN29_RS03125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CRN29_RS03130	COG0254	rRNA binding
CRN29_RS03135	COG1435	thymidine kinase activity
CRN29_RS03145	COG2890	protein-(glutamine-N5) methyltransferase activity
CRN29_RS03150	COG0009	L-threonylcarbamoyladenylate synthase
CRN29_RS03155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CRN29_RS03160	COG4475	Protein of unknown function (DUF436)
CRN29_RS03165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CRN29_RS03170	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CRN29_RS03175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CRN29_RS03185	COG0356	it plays a direct role in the translocation of protons across the membrane
CRN29_RS03195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CRN29_RS03200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CRN29_RS03205	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CRN29_RS03210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CRN29_RS03215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CRN29_RS03220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CRN29_RS03230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CRN29_RS03235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CRN29_RS03245	COG0629	single-stranded DNA binding
CRN29_RS03250	COG1388	LysM domain
CRN29_RS03255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CRN29_RS03265	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CRN29_RS03270	COG0352	thiamine-phosphate diphosphorylase activity
CRN29_RS03275	COG0706	membrane insertase activity
CRN29_RS03280	COG1418	mRNA catabolic process
CRN29_RS03285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRN29_RS03290	COG1937	Protein conserved in bacteria
CRN29_RS03305	COG0772	Belongs to the SEDS family
CRN29_RS03310	COG1181	Belongs to the D-alanine--D-alanine ligase family
CRN29_RS03315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CRN29_RS03320	COG0513	Belongs to the DEAD box helicase family
CRN29_RS03335	COG3402	PFAM membrane-flanked domain
CRN29_RS03345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CRN29_RS03355	COG2337	Toxic component of a toxin-antitoxin (TA) module
CRN29_RS03360	COG2208	phosphoserine phosphatase activity
CRN29_RS03375	COG1191	sigma factor activity
CRN29_RS03380	COG2183	response to ionizing radiation
CRN29_RS03385	COG3091	SprT-like family
CRN29_RS03420	COG0066	3-isopropylmalate dehydratase activity
CRN29_RS03425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CRN29_RS03430	COG0473	3-isopropylmalate dehydrogenase activity
CRN29_RS03435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CRN29_RS03440	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CRN29_RS03450	COG0028	Belongs to the TPP enzyme family
CRN29_RS03455	COG0129	dihydroxy-acid dehydratase activity
CRN29_RS03460	COG0802	atpase or kinase
CRN29_RS03465	COG1214	PFAM Peptidase M22, glycoprotease
CRN29_RS03470	COG0456	acetyltransferase
CRN29_RS03475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CRN29_RS03480	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CRN29_RS03485	COG0488	(ABC) transporter
CRN29_RS03490	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CRN29_RS03500	COG2391	methyltransferase activity
CRN29_RS03505	COG0425	Belongs to the sulfur carrier protein TusA family
CRN29_RS03510	COG0004	ammonium transporteR
CRN29_RS03515	COG1609	Transcriptional regulator
CRN29_RS03520	COG1621	beta-fructofuranosidase activity
CRN29_RS03525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CRN29_RS03530	COG3279	Response regulator of the LytR AlgR family
CRN29_RS03535	COG3290	protein histidine kinase activity
CRN29_RS03570	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CRN29_RS03575	COG0459	protein refolding
CRN29_RS03605	COG1725	Transcriptional regulator
CRN29_RS03620	COG1131	(ABC) transporter
CRN29_RS03665	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CRN29_RS03670	COG2706	6-phosphogluconolactonase activity
CRN29_RS03675	COG1012	belongs to the aldehyde dehydrogenase family
CRN29_RS03680	COG1227	inorganic diphosphatase activity
CRN29_RS03685	COG1335	isochorismatase
CRN29_RS03695	COG0077	Prephenate dehydratase
CRN29_RS03705	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CRN29_RS03710	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CRN29_RS03715	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CRN29_RS03725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CRN29_RS03730	COG4496	protein, YerC YecD
CRN29_RS03735	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CRN29_RS03740	COG0210	DNA helicase
CRN29_RS03745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CRN29_RS03755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CRN29_RS03760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CRN29_RS03765	COG0154	amidase activity
CRN29_RS03770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CRN29_RS03775	COG1597	lipid kinase activity
CRN29_RS03780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CRN29_RS03790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CRN29_RS03800	COG1528	Iron-storage protein
CRN29_RS03820	COG4129	membrane
CRN29_RS03825	COG0024	Methionine aminopeptidase
CRN29_RS03845	COG2197	response regulator
CRN29_RS03850	COG1295	ribonuclease BN
CRN29_RS03860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CRN29_RS03865	COG4840	Belongs to the UPF0435 family
CRN29_RS03870	COG2309	aminopeptidase activity
CRN29_RS03875	COG1607	acyl-coa hydrolase
CRN29_RS03880	COG0535	radical SAM domain protein
CRN29_RS03890	COG0693	protein deglycase activity
CRN29_RS03895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRN29_RS03900	COG2137	regulation of response to DNA damage stimulus
CRN29_RS03910	COG1134	teichoic acid transport
CRN29_RS03910	COG1388	LysM domain
CRN29_RS03920	COG1988	membrane-bound metal-dependent
CRN29_RS03930	COG3557	Belongs to the UPF0374 family
CRN29_RS03940	COG4129	membrane
CRN29_RS03945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CRN29_RS03950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CRN29_RS03955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRN29_RS03960	COG0735	belongs to the Fur family
CRN29_RS04130	COG0765	amino acid transport
CRN29_RS04135	COG1126	abc transporter atp-binding protein
CRN29_RS04140	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CRN29_RS04150	COG0363	glucosamine-6-phosphate deaminase activity
CRN29_RS04165	COG0114	fumarate hydratase activity
CRN29_RS04170	COG0564	pseudouridine synthase activity
CRN29_RS04175	COG2203	Gaf domain
CRN29_RS04175	COG4585	Histidine kinase
CRN29_RS04180	COG2197	response regulator
CRN29_RS04190	COG4399	Belongs to the UPF0754 family
CRN29_RS04195	COG3679	Belongs to the UPF0342 family
CRN29_RS04200	COG0420	3'-5' exonuclease activity
CRN29_RS04210	COG3481	metal-dependent phosphohydrolase, HD sub domain
CRN29_RS04220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CRN29_RS04235	COG0537	adenosine 5'-monophosphoramidase activity
CRN29_RS04240	COG1131	(ABC) transporter
CRN29_RS04245	COG4473	ABC transporter
CRN29_RS04250	COG2329	Antibiotic biosynthesis monooxygenase
CRN29_RS04255	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CRN29_RS04260	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CRN29_RS04265	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CRN29_RS04355	COG3646	Phage regulatory protein
CRN29_RS04355	COG3645	SOS response
CRN29_RS04425	COG1484	DNA-dependent DNA replication
CRN29_RS04640	COG5632	N-Acetylmuramoyl-L-alanine amidase
CRN29_RS04640	COG1388	LysM domain
CRN29_RS04660	COG0318	PFAM AMP-dependent synthetase and ligase
CRN29_RS04675	COG0494	nUDIX hydrolase
CRN29_RS04680	COG1506	peptidase
CRN29_RS04690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CRN29_RS04700	COG0656	L-ascorbic acid biosynthetic process
CRN29_RS04705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CRN29_RS04710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CRN29_RS04720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CRN29_RS04735	COG1595	DNA-templated transcription, initiation
CRN29_RS04745	COG4193	domain, Protein
CRN29_RS04745	COG5632	N-Acetylmuramoyl-L-alanine amidase
CRN29_RS04745	COG3266	domain, Protein
CRN29_RS04755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CRN29_RS04755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CRN29_RS04765	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CRN29_RS04765	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CRN29_RS04770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CRN29_RS04775	COG0506	proline dehydrogenase activity
CRN29_RS04780	COG2267	carboxylic ester hydrolase activity
CRN29_RS04790	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CRN29_RS04795	COG1242	4 iron, 4 sulfur cluster binding
CRN29_RS04800	COG2814	Major facilitator Superfamily
CRN29_RS04805	COG0495	leucyl-tRNA aminoacylation
CRN29_RS04810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRN29_RS04820	COG2081	HI0933 family
CRN29_RS04825	COG2244	polysaccharide biosynthetic process
CRN29_RS04830	COG1187	pseudouridine synthase activity
CRN29_RS04840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRN29_RS04845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CRN29_RS04850	COG0510	thiamine kinase activity
CRN29_RS04855	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CRN29_RS04860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRN29_RS04870	COG1363	Peptidase, m42
CRN29_RS04875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRN29_RS04880	COG4848	Belongs to the UPF0354 family
CRN29_RS04885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRN29_RS04890	COG1674	ftsk spoiiie
CRN29_RS04895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CRN29_RS04900	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CRN29_RS04910	COG1605	Chorismate mutase
CRN29_RS04910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CRN29_RS04915	COG1609	Transcriptional regulator
CRN29_RS04925	COG0454	-acetyltransferase
CRN29_RS04930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CRN29_RS04935	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CRN29_RS04940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRN29_RS04945	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CRN29_RS04955	COG2814	Major facilitator Superfamily
CRN29_RS04960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRN29_RS04965	COG0204	Acyl-transferase
CRN29_RS04970	COG1263	PTS System
CRN29_RS04970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN29_RS04980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CRN29_RS04990	COG1764	response to oxidative stress
CRN29_RS04995	COG0584	glycerophosphoryl diester phosphodiesterase
CRN29_RS05000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CRN29_RS05010	COG1956	GAF domain-containing protein
CRN29_RS05015	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CRN29_RS05020	COG1104	cysteine desulfurase activity
CRN29_RS05025	COG0301	tRNA thio-modification
CRN29_RS05035	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CRN29_RS05040	COG0827	DNA restriction-modification system
CRN29_RS05045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CRN29_RS05050	COG0589	response to stress
CRN29_RS05060	COG0006	proline dipeptidase activity
CRN29_RS05065	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CRN29_RS05075	COG4109	DRTGG domain
CRN29_RS05080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CRN29_RS05085	COG0587	DNA-directed DNA polymerase activity
CRN29_RS05090	COG0281	malic enzyme
CRN29_RS05095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CRN29_RS05100	COG0825	malonyl-CoA metabolic process
CRN29_RS05105	COG0205	6-phosphofructokinase activity
CRN29_RS05110	COG0469	pyruvate kinase activity
CRN29_RS05115	COG1113	amino acid transport
CRN29_RS05120	COG0372	Belongs to the citrate synthase family
CRN29_RS05125	COG0538	isocitrate dehydrogenase activity
CRN29_RS05130	COG0745	RESPONSE REGULATOR receiver
CRN29_RS05135	COG5002	protein histidine kinase activity
CRN29_RS05140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRN29_RS05140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRN29_RS05150	COG0237	dephospho-CoA kinase activity
CRN29_RS05155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CRN29_RS05160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CRN29_RS05170	COG1484	DNA-dependent DNA replication
CRN29_RS05175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CRN29_RS05180	COG0833	amino acid
CRN29_RS05185	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CRN29_RS05190	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CRN29_RS05195	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CRN29_RS05200	COG4112	unkown
CRN29_RS05210	COG0544	peptidyl-prolyl cis-trans isomerase activity
CRN29_RS05215	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CRN29_RS05220	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CRN29_RS05225	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CRN29_RS05230	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CRN29_RS05235	COG0181	hydroxymethylbilane synthase activity
CRN29_RS05245	COG0113	porphobilinogen synthase activity
CRN29_RS05250	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CRN29_RS05260	COG2818	Glycosylase
CRN29_RS05265	COG0525	valine-tRNA ligase activity
CRN29_RS05270	COG0285	dihydrofolate synthase activity
CRN29_RS05280	COG2003	Belongs to the UPF0758 family
CRN29_RS05315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CRN29_RS05320	COG2868	ribosomal protein
CRN29_RS05325	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CRN29_RS05330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CRN29_RS05335	COG4492	Belongs to the UPF0735 family
CRN29_RS05340	COG0632	four-way junction helicase activity
CRN29_RS05345	COG2255	four-way junction helicase activity
CRN29_RS05350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CRN29_RS05360	COG1862	Preprotein translocase
CRN29_RS05365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CRN29_RS05365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CRN29_RS05370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CRN29_RS05370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CRN29_RS05380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CRN29_RS05385	COG1490	D-aminoacyl-tRNA deacylase activity
CRN29_RS05390	COG0860	N-Acetylmuramoyl-L-alanine amidase
CRN29_RS05400	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CRN29_RS05410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CRN29_RS05415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CRN29_RS05420	COG1959	2 iron, 2 sulfur cluster binding
CRN29_RS05430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRN29_RS05435	COG1104	cysteine desulfurase activity
CRN29_RS05440	COG0482	sulfurtransferase activity
CRN29_RS05450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CRN29_RS05455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CRN29_RS05460	COG4472	Bacterial protein of unknown function (DUF965)
CRN29_RS05465	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CRN29_RS05470	COG3906	Belongs to the UPF0473 family
CRN29_RS05480	COG0826	peptidase U32
CRN29_RS05485	COG0826	peptidase U32
CRN29_RS05490	COG0572	uridine kinase
CRN29_RS05495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CRN29_RS05500	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CRN29_RS05505	COG1984	allophanate hydrolase subunit 2
CRN29_RS05510	COG0511	ligase activity, forming carbon-carbon bonds
CRN29_RS05515	COG0439	Biotin carboxylase
CRN29_RS05520	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CRN29_RS05525	COG1914	H( )-stimulated, divalent metal cation uptake system
CRN29_RS05530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CRN29_RS05535	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CRN29_RS05540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CRN29_RS05550	COG1534	Rna-binding protein
CRN29_RS05555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CRN29_RS05560	COG1713	HD superfamily hydrolase involved in NAD metabolism
CRN29_RS05565	COG0799	negative regulation of ribosome biogenesis
CRN29_RS05570	COG2226	methyltransferase
CRN29_RS05575	COG1555	photosystem II stabilization
CRN29_RS05575	COG1596	polysaccharide export
CRN29_RS05580	COG2131	deaminase
CRN29_RS05590	COG1466	dna polymerase III delta subunit
CRN29_RS05595	COG0268	Binds directly to 16S ribosomal RNA
CRN29_RS05600	COG0481	GTPase activity
CRN29_RS05605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CRN29_RS05610	COG1420	regulation of RNA biosynthetic process
CRN29_RS05615	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CRN29_RS05620	COG0443	Heat shock 70 kDa protein
CRN29_RS05625	COG0484	heat shock protein binding
CRN29_RS05630	COG2264	protein methyltransferase activity
CRN29_RS05635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CRN29_RS05640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CRN29_RS05650	COG1030	water channel activity
CRN29_RS05655	COG4864	UPF0365 protein
CRN29_RS05665	COG1702	phosphate starvation-inducible protein PhoH
CRN29_RS05670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CRN29_RS05680	COG0295	cytidine deaminase activity
CRN29_RS05685	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CRN29_RS05690	COG1381	Involved in DNA repair and RecF pathway recombination
CRN29_RS05695	COG0423	glycine-tRNA ligase activity
CRN29_RS05700	COG0517	IMP dehydrogenase activity
CRN29_RS05705	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CRN29_RS05710	COG0358	DNA primase activity
CRN29_RS05715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CRN29_RS05720	COG2384	SAM-dependent methyltransferase
CRN29_RS05725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CRN29_RS05730	COG0513	Belongs to the DEAD box helicase family
CRN29_RS05735	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CRN29_RS05740	COG1121	(ABC) transporter
CRN29_RS05745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CRN29_RS05760	COG0768	penicillin binding
CRN29_RS05765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CRN29_RS05770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CRN29_RS05780	COG4483	Protein conserved in bacteria
CRN29_RS05785	COG1940	carbohydrate kinase activity
CRN29_RS05790	COG0011	TIGRFAM Protein of
CRN29_RS05795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRN29_RS05800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CRN29_RS05805	COG1459	type II secretion system
CRN29_RS05810	COG4537	Required for transformation and DNA binding
CRN29_RS05835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CRN29_RS05840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CRN29_RS05855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRN29_RS05860	COG0095	Lipoate-protein ligase
CRN29_RS05875	COG0006	proline dipeptidase activity
CRN29_RS05880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CRN29_RS05885	COG0511	ligase activity, forming carbon-carbon bonds
CRN29_RS05890	COG0439	Biotin carboxylase
CRN29_RS05895	COG1302	Protein conserved in bacteria
CRN29_RS05900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CRN29_RS05905	COG1570	exodeoxyribonuclease VII activity
CRN29_RS05910	COG1722	exodeoxyribonuclease VII activity
CRN29_RS05920	COG1438	arginine binding
CRN29_RS05925	COG0497	DNA recombination
CRN29_RS05930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRN29_RS05935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CRN29_RS05940	COG0022	dehydrogenase e1 component
CRN29_RS05945	COG0508	dehydrogenase complex catalyzes the overall conversion of
CRN29_RS05955	COG4129	membrane
CRN29_RS05960	COG2195	Cleaves the N-terminal amino acid of tripeptides
CRN29_RS05965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CRN29_RS05970	COG0366	Alpha amylase catalytic
CRN29_RS05980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CRN29_RS05985	COG1234	tRNA 3'-trailer cleavage
CRN29_RS05990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CRN29_RS05995	COG0300	oxidoreductase activity
CRN29_RS06005	COG0667	Aldo Keto reductase
CRN29_RS06010	COG0494	nUDIX hydrolase
CRN29_RS06015	COG0735	belongs to the Fur family
CRN29_RS06020	COG4974	Belongs to the 'phage' integrase family
CRN29_RS06030	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CRN29_RS06035	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CRN29_RS06040	COG1187	pseudouridine synthase activity
CRN29_RS06045	COG0745	RESPONSE REGULATOR receiver
CRN29_RS06060	COG1141	Ferredoxin
CRN29_RS06070	COG0514	ATP-dependent DNA helicase (RecQ)
CRN29_RS06075	COG1388	LysM domain
CRN29_RS06075	COG1388	LysM domain
CRN29_RS06080	COG0492	ferredoxin-NADP+ reductase activity
CRN29_RS06090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CRN29_RS06095	COG0539	negative regulation of cytoplasmic translation
CRN29_RS06100	COG1160	GTP binding
CRN29_RS06105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CRN29_RS06120	COG2226	methyltransferase
CRN29_RS06125	COG0142	geranyltranstransferase activity
CRN29_RS06130	COG0105	UTP biosynthetic process
CRN29_RS06135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CRN29_RS06140	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CRN29_RS06145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CRN29_RS06155	COG5582	Belongs to the UPF0302 family
CRN29_RS06160	COG4347	Protein of unknown function (DUF1405)
CRN29_RS06165	COG2738	Putative neutral zinc metallopeptidase
CRN29_RS06170	COG1694	Mazg nucleotide pyrophosphohydrolase
CRN29_RS06175	COG0438	transferase activity, transferring glycosyl groups
CRN29_RS06180	COG0617	tRNA 3'-terminal CCA addition
CRN29_RS06190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CRN29_RS06190	COG1199	ATP-dependent helicase activity
CRN29_RS06195	COG0017	Asparaginyl-tRNA synthetase
CRN29_RS06200	COG3935	DnaD domain protein
CRN29_RS06205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CRN29_RS06215	COG4499	WXG100 protein secretion system (Wss), protein YukC
CRN29_RS06215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRN29_RS06220	COG3331	DNA recombination
CRN29_RS06230	COG4474	Belongs to the UPF0398 family
CRN29_RS06235	COG3599	regulation of cell shape
CRN29_RS06245	COG0116	Belongs to the methyltransferase superfamily
CRN29_RS06255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CRN29_RS06260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRN29_RS06270	COG0328	RNA-DNA hybrid ribonuclease activity
CRN29_RS06275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CRN29_RS06285	COG1413	lyase activity
CRN29_RS06290	COG1413	lyase activity
CRN29_RS06320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CRN29_RS06325	COG2190	(PTS) system
CRN29_RS06330	COG4479	Belongs to the UPF0346 family
CRN29_RS06335	COG0793	Belongs to the peptidase S41A family
CRN29_RS06345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CRN29_RS06350	COG0671	phosphoesterase, PA-phosphatase related
CRN29_RS06355	COG3842	ATPase activity
CRN29_RS06360	COG4209	transmembrane transport
CRN29_RS06370	COG0395	ABC-type sugar transport system, permease component
CRN29_RS06380	COG0534	Mate efflux family protein
CRN29_RS06385	COG1349	DNA-binding transcription factor activity
CRN29_RS06390	COG0745	RESPONSE REGULATOR receiver
CRN29_RS06395	COG5002	protein histidine kinase activity
CRN29_RS06405	COG0567	Dehydrogenase, E1 component
CRN29_RS06420	COG1131	(ABC) transporter
CRN29_RS06445	COG0714	Associated with various cellular activities
CRN29_RS06450	COG4548	von Willebrand factor, type A
CRN29_RS06455	COG1114	Component of the transport system for branched-chain amino acids
CRN29_RS06460	COG3853	Toxic anion resistance protein (TelA)
CRN29_RS06470	COG1254	Belongs to the acylphosphatase family
CRN29_RS06480	COG1278	Cold shock
CRN29_RS06500	COG1473	amidohydrolase
CRN29_RS06510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CRN29_RS06515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CRN29_RS06520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CRN29_RS06525	COG0527	aspartate kinase activity
CRN29_RS06530	COG0488	(ABC) transporter
CRN29_RS06535	COG2996	Protein conserved in bacteria
CRN29_RS06540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CRN29_RS06545	COG0573	inorganic phosphate transmembrane transporter activity
CRN29_RS06550	COG0581	inorganic phosphate transmembrane transporter activity
CRN29_RS06555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CRN29_RS06560	COG0704	Plays a role in the regulation of phosphate uptake
CRN29_RS06565	COG1164	Oligoendopeptidase f
CRN29_RS06600	COG2348	transferase activity, transferring amino-acyl groups
CRN29_RS06605	COG2348	transferase activity, transferring amino-acyl groups
CRN29_RS06615	COG0159	tryptophan synthase activity
CRN29_RS06625	COG0135	phosphoribosylanthranilate isomerase activity
CRN29_RS06630	COG0134	indole-3-glycerol-phosphate synthase activity
CRN29_RS06635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CRN29_RS06640	COG0512	Glutamine amidotransferase of anthranilate synthase
CRN29_RS06645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CRN29_RS06650	COG1363	Peptidase, m42
CRN29_RS06655	COG0287	Prephenate dehydrogenase
CRN29_RS06660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CRN29_RS06665	COG1942	4-Oxalocrotonate Tautomerase
CRN29_RS06680	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CRN29_RS06680	COG0392	lysyltransferase activity
CRN29_RS06685	COG0628	permease
CRN29_RS06690	COG3711	transcriptional antiterminator
CRN29_RS06695	COG1115	amino acid carrier protein
CRN29_RS06700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CRN29_RS06705	COG0187	DNA topoisomerase II activity
CRN29_RS06710	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CRN29_RS06720	COG0824	Thioesterase
CRN29_RS06725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CRN29_RS06730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CRN29_RS06735	COG1970	mechanosensitive ion channel activity
CRN29_RS06740	COG0419	ATPase involved in DNA repair
CRN29_RS06745	COG0420	3'-5' exonuclease activity
CRN29_RS06750	COG4846	Membrane protein involved in cytochrome C biogenesis
CRN29_RS06760	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CRN29_RS06765	COG4224	UPF0291 protein
CRN29_RS06775	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CRN29_RS06780	COG2340	Cysteine-rich secretory protein family
CRN29_RS06785	COG0516	GMP reductase activity
CRN29_RS06790	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CRN29_RS06800	COG0753	catalase activity
CRN29_RS06805	COG0833	amino acid
CRN29_RS06820	COG0083	homoserine kinase activity
CRN29_RS06825	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CRN29_RS06830	COG0460	homoserine dehydrogenase
CRN29_RS06835	COG0527	aspartate kinase activity
CRN29_RS06850	COG1525	nuclease
CRN29_RS06865	COG2197	response regulator
CRN29_RS06870	COG4585	Histidine kinase
CRN29_RS06880	COG1131	(ABC) transporter
CRN29_RS06885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRN29_RS06930	COG0789	Transcriptional regulator
CRN29_RS06935	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CRN29_RS06940	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CRN29_RS06945	COG0386	Belongs to the glutathione peroxidase family
CRN29_RS06950	COG1923	regulation of RNA biosynthetic process
CRN29_RS06955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CRN29_RS06965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CRN29_RS06970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CRN29_RS06975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CRN29_RS06985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CRN29_RS06990	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CRN29_RS07000	COG4550	Control of competence regulator ComK, YlbF/YmcA
CRN29_RS07005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CRN29_RS07015	COG4195	phage-related replication protein
CRN29_RS07020	COG1013	pyruvate-flavodoxin oxidoreductase activity
CRN29_RS07025	COG0674	pyruvate-flavodoxin oxidoreductase activity
CRN29_RS07025	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CRN29_RS07030	COG1692	metallophosphoesterase
CRN29_RS07040	COG1418	mRNA catabolic process
CRN29_RS07045	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CRN29_RS07050	COG1546	Belongs to the CinA family
CRN29_RS07050	COG1058	Belongs to the CinA family
CRN29_RS07055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CRN29_RS07070	COG0300	oxidoreductase activity
CRN29_RS07075	COG0612	Peptidase, M16
CRN29_RS07080	COG0612	Peptidase, M16
CRN29_RS07085	COG2188	Transcriptional regulator
CRN29_RS07090	COG1674	ftsk spoiiie
CRN29_RS07095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CRN29_RS07100	COG1185	polyribonucleotide nucleotidyltransferase activity
CRN29_RS07105	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CRN29_RS07110	COG0196	riboflavin kinase activity
CRN29_RS07115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CRN29_RS07120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CRN29_RS07125	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CRN29_RS07130	COG1358	cellular component organization or biogenesis
CRN29_RS07135	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CRN29_RS07140	COG0195	Participates in both transcription termination and antitermination
CRN29_RS07145	COG0779	Required for maturation of 30S ribosomal subunits
CRN29_RS07150	COG2176	DNA-directed DNA polymerase activity
CRN29_RS07155	COG0442	prolyl-tRNA aminoacylation
CRN29_RS07165	COG4589	Belongs to the CDS family
CRN29_RS07170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CRN29_RS07175	COG0233	cytoplasmic translational termination
CRN29_RS07180	COG0528	UMP kinase activity
CRN29_RS07185	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CRN29_RS07190	COG0052	Belongs to the universal ribosomal protein uS2 family
CRN29_RS07205	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CRN29_RS07210	COG4974	Belongs to the 'phage' integrase family
CRN29_RS07215	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CRN29_RS07220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CRN29_RS07225	COG0758	DNA mediated transformation
CRN29_RS07230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CRN29_RS07235	COG0045	succinate-CoA ligase (ADP-forming) activity
CRN29_RS07240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CRN29_RS07250	COG4485	Bacterial membrane protein, YfhO
CRN29_RS07270	COG0335	large ribosomal subunit rRNA binding
CRN29_RS07275	COG0336	Belongs to the RNA methyltransferase TrmD family
CRN29_RS07280	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CRN29_RS07285	COG0228	four-way junction DNA binding
CRN29_RS07290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CRN29_RS07295	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CRN29_RS07300	COG0552	protein localization to endoplasmic reticulum
CRN29_RS07305	COG1196	nuclear chromosome segregation
CRN29_RS07310	COG0571	ribonuclease III activity
CRN29_RS07315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRN29_RS07330	COG0416	fatty acid biosynthetic process
CRN29_RS07335	COG1349	DNA-binding transcription factor activity
CRN29_RS07340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CRN29_RS07355	COG1461	Dihydroxyacetone kinase
CRN29_RS07360	COG1302	Protein conserved in bacteria
CRN29_RS07365	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CRN29_RS07370	COG1564	THIamine pyrophosphokinase
CRN29_RS07375	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CRN29_RS07380	COG1162	GTPase activity
CRN29_RS07385	COG2807	transmembrane transport
CRN29_RS07395	COG0631	protein serine/threonine phosphatase activity
CRN29_RS07400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CRN29_RS07405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CRN29_RS07405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CRN29_RS07410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CRN29_RS07415	COG0242	peptide deformylase activity
CRN29_RS07425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CRN29_RS07430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CRN29_RS07435	COG1758	RNA polymerase activity
CRN29_RS07440	COG0194	GDP metabolic process
CRN29_RS07445	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CRN29_RS07460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CRN29_RS07465	COG0284	orotidine-5'-phosphate decarboxylase activity
CRN29_RS07470	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CRN29_RS07475	COG0505	Belongs to the CarA family
CRN29_RS07480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CRN29_RS07485	COG0540	Belongs to the ATCase OTCase family
CRN29_RS07490	COG2233	PERMEase
CRN29_RS07495	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CRN29_RS07500	COG0564	pseudouridine synthase activity
CRN29_RS07505	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CRN29_RS07515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CRN29_RS07520	COG3599	regulation of cell shape
CRN29_RS07530	COG0762	integral membrane protein
CRN29_RS07535	COG1799	cell septum assembly
CRN29_RS07540	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CRN29_RS07545	COG1496	oxidoreductase activity
CRN29_RS07550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CRN29_RS07555	COG0849	cell division
CRN29_RS07560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CRN29_RS07565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CRN29_RS07570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CRN29_RS07575	COG0768	penicillin binding
CRN29_RS07580	COG4839	cell division protein FtsL
CRN29_RS07585	COG0275	rRNA processing
CRN29_RS07595	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CRN29_RS07600	COG0454	-acetyltransferase
CRN29_RS07605	COG1011	Hydrolase
CRN29_RS07650	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CRN29_RS07655	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CRN29_RS07660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CRN29_RS07665	COG1053	succinate dehydrogenase
CRN29_RS07670	COG2009	succinate dehydrogenase
CRN29_RS07675	COG0322	excinuclease ABC activity
CRN29_RS07680	COG3118	belongs to the thioredoxin family
CRN29_RS07685	COG1193	negative regulation of DNA recombination
CRN29_RS07690	COG1796	DNA polymerase
CRN29_RS07690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CRN29_RS07700	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CRN29_RS07705	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CRN29_RS07710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRN29_RS07710	COG0072	phenylalanine-tRNA ligase activity
CRN29_RS07715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CRN29_RS07720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CRN29_RS07730	COG4509	Sortase family
CRN29_RS07775	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CRN29_RS07795	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CRN29_RS07800	COG0742	ribosomal rna small subunit methyltransferase
CRN29_RS07810	COG4471	UPF0298 protein
CRN29_RS07815	COG0584	glycerophosphoryl diester phosphodiesterase
CRN29_RS07820	COG3679	Belongs to the UPF0342 family
CRN29_RS07835	COG0109	protoheme IX farnesyltransferase activity
CRN29_RS07840	COG1612	heme a metabolic process
CRN29_RS07850	COG0772	Belongs to the SEDS family
CRN29_RS07855	COG4838	Belongs to the UPF0358 family
CRN29_RS07860	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CRN29_RS07865	COG4896	Protein conserved in bacteria
CRN29_RS07870	COG1217	gtp-binding protein TYPA
CRN29_RS07880	COG0483	inositol monophosphate 1-phosphatase activity
CRN29_RS07885	COG4493	Belongs to the UPF0637 family
CRN29_RS07890	COG1914	H( )-stimulated, divalent metal cation uptake system
CRN29_RS07910	COG1177	transmembrane transport
CRN29_RS07915	COG1176	ABC-type spermidine putrescine transport system, permease component I
CRN29_RS07930	COG4476	Belongs to the UPF0223 family
CRN29_RS07940	COG0508	dehydrogenase complex catalyzes the overall conversion of
CRN29_RS07945	COG0022	dehydrogenase e1 component
CRN29_RS07950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CRN29_RS07960	COG0242	peptide deformylase activity
CRN29_RS07965	COG5503	Protein of unknown function (DUF1447)
CRN29_RS07970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CRN29_RS07980	COG0569	domain protein
CRN29_RS07985	COG1294	oxidase, subunit
CRN29_RS07990	COG1271	oxidase subunit
CRN29_RS08005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN29_RS08015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CRN29_RS08035	COG4172	Belongs to the ABC transporter superfamily
CRN29_RS08040	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CRN29_RS08045	COG0151	Belongs to the GarS family
CRN29_RS08050	COG0138	bifunctional purine biosynthesis protein purh
CRN29_RS08055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CRN29_RS08060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CRN29_RS08065	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CRN29_RS08070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CRN29_RS08075	COG0047	phosphoribosylformylglycinamidine synthase activity
CRN29_RS08080	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CRN29_RS08085	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CRN29_RS08090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CRN29_RS08095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CRN29_RS08100	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CRN29_RS08105	COG1017	nitric oxide dioxygenase activity
CRN29_RS08105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CRN29_RS08115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CRN29_RS08120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CRN29_RS08130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CRN29_RS08145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CRN29_RS08150	COG1316	TRANSCRIPTIONal
CRN29_RS08175	COG3594	Acyltransferase
CRN29_RS08180	COG0436	Aminotransferase
CRN29_RS08185	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CRN29_RS08195	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CRN29_RS08200	COG1169	isochorismate synthase
CRN29_RS08205	COG1575	Belongs to the MenA family. Type 1 subfamily
CRN29_RS08295	COG4873	Protein conserved in bacteria
CRN29_RS08305	COG0737	Belongs to the 5'-nucleotidase family
CRN29_RS08310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CRN29_RS08315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRN29_RS08320	COG0861	Integral membrane protein TerC family
CRN29_RS08325	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CRN29_RS08335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CRN29_RS08340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CRN29_RS08345	COG2814	Major facilitator Superfamily
CRN29_RS08350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CRN29_RS08355	COG2382	esterase
CRN29_RS08360	COG0628	permease
CRN29_RS08370	COG0475	glutathione-regulated potassium exporter activity
CRN29_RS08370	COG0569	domain protein
CRN29_RS08375	COG2239	Acts as a magnesium transporter
CRN29_RS08380	COG0564	pseudouridine synthase activity
CRN29_RS08385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CRN29_RS08390	COG2357	RelA SpoT domain protein
CRN29_RS08400	COG4116	CYTH
CRN29_RS08405	COG2346	COG2346, Truncated hemoglobins
CRN29_RS08410	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CRN29_RS08415	COG1164	Oligoendopeptidase f
CRN29_RS08425	COG4862	establishment of competence for transformation
CRN29_RS08430	COG1393	Belongs to the ArsC family
CRN29_RS08435	COG0180	Tryptophanyl-tRNA synthetase
CRN29_RS08440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRN29_RS08445	COG0601	transmembrane transport
CRN29_RS08450	COG4608	Belongs to the ABC transporter superfamily
CRN29_RS08455	COG0444	Belongs to the ABC transporter superfamily
CRN29_RS08460	COG0747	negative chemotaxis
CRN29_RS08470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CRN29_RS08480	COG1881	PFAM PEBP family protein
CRN29_RS08485	COG0542	response to heat
CRN29_RS08500	COG0561	phosphatase activity
CRN29_RS08505	COG0446	pyridine nucleotide-disulphide oxidoreductase
CRN29_RS08515	COG0179	Fumarylacetoacetate (FAA) hydrolase
CRN29_RS08520	COG1074	ATP-dependent DNA helicase activity
CRN29_RS08525	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CRN29_RS08540	COG0398	Pfam SNARE associated Golgi protein
CRN29_RS08545	COG0166	Belongs to the GPI family
CRN29_RS08550	COG0137	argininosuccinate synthase activity
CRN29_RS08555	COG0165	Argininosuccinate lyase
CRN29_RS08560	COG0584	glycerophosphoryl diester phosphodiesterase
CRN29_RS08575	COG1902	pentaerythritol trinitrate reductase activity
CRN29_RS08580	COG1098	S1 RNA binding domain
CRN29_RS08585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CRN29_RS08595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CRN29_RS08595	COG2111	Na H antiporter
CRN29_RS08600	COG2111	Na H antiporter
CRN29_RS08605	COG1006	Multisubunit Na H antiporter MnhC subunit
CRN29_RS08610	COG0651	ATP synthesis coupled electron transport
CRN29_RS08615	COG1863	multisubunit Na H antiporter MnhE subunit
CRN29_RS08620	COG2212	antiporter activity
CRN29_RS08625	COG1320	monovalent cation:proton antiporter activity
CRN29_RS08635	COG2050	protein possibly involved in aromatic compounds catabolism
CRN29_RS08640	COG2056	Na+-H+ antiporter family
CRN29_RS08645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CRN29_RS08650	COG1252	NADH dehydrogenase
CRN29_RS08655	COG0316	Belongs to the HesB IscA family
CRN29_RS08660	COG4844	belongs to the
CRN29_RS08665	COG1252	NADH dehydrogenase
CRN29_RS08670	COG4837	Protein of unknown function (DUF1462)
CRN29_RS08675	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CRN29_RS08680	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CRN29_RS08690	COG1696	Membrane protein involved in D-alanine export
CRN29_RS08695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CRN29_RS08705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CRN29_RS08710	COG0647	UMP catabolic process
CRN29_RS08715	COG2445	Protein of unknown function DUF86
CRN29_RS08725	COG4470	Protein conserved in bacteria
CRN29_RS08730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CRN29_RS08735	COG0737	Belongs to the 5'-nucleotidase family
CRN29_RS08740	COG0730	response to heat
CRN29_RS08745	COG1801	Protein of unknown function DUF72
CRN29_RS08750	COG2070	2-Nitropropane dioxygenase
CRN29_RS08755	COG1253	flavin adenine dinucleotide binding
CRN29_RS08760	COG0719	Fe-S assembly protein
CRN29_RS08765	COG0822	iron-sulfur transferase activity
CRN29_RS08770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CRN29_RS08775	COG0719	Fe-S assembly protein
CRN29_RS08780	COG0396	ATPase activity
CRN29_RS08800	COG1464	Belongs to the NlpA lipoprotein family
CRN29_RS08805	COG2011	ABC-type metal ion transport system permease component
CRN29_RS08810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CRN29_RS08820	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CRN29_RS08825	COG0509	glycine decarboxylation via glycine cleavage system
CRN29_RS08830	COG1393	Belongs to the ArsC family
CRN29_RS08835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRN29_RS08845	COG0710	3-dehydroquinate dehydratase activity
CRN29_RS08850	COG1764	response to oxidative stress
CRN29_RS08860	COG1279	arginine transmembrane transporter activity
CRN29_RS08865	COG0406	alpha-ribazole phosphatase activity
CRN29_RS08905	COG4195	phage-related replication protein
CRN29_RS08925	COG1278	Cold shock
CRN29_RS08950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CRN29_RS08955	COG0557	exoribonuclease II activity
CRN29_RS08960	COG1647	Serine aminopeptidase, S33
CRN29_RS08965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CRN29_RS08975	COG0148	phosphopyruvate hydratase activity
CRN29_RS08980	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CRN29_RS08985	COG0149	triose-phosphate isomerase activity
CRN29_RS08990	COG0126	phosphoglycerate kinase activity
CRN29_RS08995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CRN29_RS09000	COG2390	Transcriptional regulator
CRN29_RS09015	COG1090	epimerase
CRN29_RS09035	COG1481	regulation of sporulation
CRN29_RS09040	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CRN29_RS09045	COG1660	Displays ATPase and GTPase activities
CRN29_RS09050	COG0492	ferredoxin-NADP+ reductase activity
CRN29_RS09065	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CRN29_RS09070	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CRN29_RS09075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CRN29_RS09080	COG0556	nucleotide-excision repair
CRN29_RS09095	COG1388	LysM domain
CRN29_RS09095	COG3942	CHAP domain
CRN29_RS09105	COG0653	protein targeting
CRN29_RS09115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CRN29_RS09120	COG1040	competence protein
CRN29_RS09125	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CRN29_RS09135	COG1739	Uncharacterized protein family UPF0029
CRN29_RS09140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CRN29_RS09160	COG2195	Cleaves the N-terminal amino acid of tripeptides
CRN29_RS09165	COG1929	Belongs to the glycerate kinase type-1 family
CRN29_RS09185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CRN29_RS09195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRN29_RS09200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRN29_RS09205	COG1780	Probably involved in ribonucleotide reductase function
CRN29_RS09220	COG3104	oligopeptide transport
CRN29_RS09225	COG1597	lipid kinase activity
CRN29_RS09235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CRN29_RS09240	COG1174	glycine betaine transport
CRN29_RS09250	COG0514	ATP-dependent DNA helicase (RecQ)
CRN29_RS09255	COG0488	(ABC) transporter
CRN29_RS09265	COG1368	sulfuric ester hydrolase activity
CRN29_RS09275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CRN29_RS09290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CRN29_RS09300	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CRN29_RS09305	COG0720	synthase
CRN29_RS09310	COG0602	queuosine metabolic process
CRN29_RS09330	COG0745	RESPONSE REGULATOR receiver
CRN29_RS09335	COG5002	protein histidine kinase activity
CRN29_RS09340	COG0463	Glycosyl transferase, family 2
CRN29_RS09345	COG0656	L-ascorbic acid biosynthetic process
CRN29_RS09350	COG1253	flavin adenine dinucleotide binding
CRN29_RS09355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CRN29_RS09360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRN29_RS09360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRN29_RS09360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRN29_RS09365	COG1105	Belongs to the carbohydrate kinase PfkB family
CRN29_RS09370	COG1349	DNA-binding transcription factor activity
CRN29_RS09375	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CRN29_RS09405	COG0471	metal ion transport
CRN29_RS09410	COG0039	L-malate dehydrogenase activity
CRN29_RS09430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CRN29_RS09435	COG4988	ABC transporter
CRN29_RS09440	COG1968	undecaprenyl-diphosphatase activity
CRN29_RS09450	COG1671	Belongs to the UPF0178 family
CRN29_RS09455	COG1611	Belongs to the LOG family
CRN29_RS09460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRN29_RS09485	COG2839	Protein conserved in bacteria
CRN29_RS09495	COG0583	DNA-binding transcription factor activity
CRN29_RS09510	COG0217	transcriptional regulatory protein
CRN29_RS09520	COG4977	sequence-specific DNA binding
CRN29_RS09520	COG1917	Cupin 2, conserved barrel domain protein
CRN29_RS09530	COG3942	CHAP domain
CRN29_RS09530	COG1388	LysM domain
CRN29_RS09535	COG0306	phosphate transporter
CRN29_RS09540	COG1392	Phosphate transport regulator
CRN29_RS09545	COG0577	efflux transmembrane transporter activity
CRN29_RS09550	COG1136	(ABC) transporter
CRN29_RS09555	COG2205	protein histidine kinase activity
CRN29_RS09560	COG0745	RESPONSE REGULATOR receiver
CRN29_RS09565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CRN29_RS09575	COG0657	acetylesterase activity
CRN29_RS09580	COG3949	Membrane
CRN29_RS09590	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CRN29_RS09600	COG2376	Dihydroxyacetone kinase
CRN29_RS09605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN29_RS09610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN29_RS09615	COG1120	ATPase activity
CRN29_RS09620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRN29_RS09625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CRN29_RS09630	COG1132	(ABC) transporter
CRN29_RS09635	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CRN29_RS09645	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CRN29_RS09650	COG1682	transport, permease protein
CRN29_RS09655	COG1134	teichoic acid transport
CRN29_RS09660	COG5609	conserved protein (DUF2294)
CRN29_RS09670	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CRN29_RS09680	COG1321	iron dependent repressor
CRN29_RS09685	COG1121	(ABC) transporter
CRN29_RS09690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CRN29_RS09695	COG0803	Belongs to the bacterial solute-binding protein 9 family
CRN29_RS09705	COG1320	monovalent cation:proton antiporter activity
CRN29_RS09710	COG2212	antiporter activity
CRN29_RS09715	COG1863	multisubunit Na H antiporter MnhE subunit
CRN29_RS09720	COG0651	ATP synthesis coupled electron transport
CRN29_RS09725	COG1006	Multisubunit Na H antiporter MnhC subunit
CRN29_RS09730	COG2111	Na H antiporter
CRN29_RS09735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CRN29_RS09735	COG2111	Na H antiporter
CRN29_RS09770	COG0596	Alpha beta hydrolase
CRN29_RS09795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRN29_RS09800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CRN29_RS09810	COG0789	Transcriptional regulator
CRN29_RS09820	COG0018	arginyl-trna synthetase
CRN29_RS09840	COG3875	lactate racemase activity
CRN29_RS09845	COG1606	tRNA processing
CRN29_RS09850	COG1691	(AIR) carboxylase
CRN29_RS09855	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CRN29_RS09870	COG1078	dGTPase activity
CRN29_RS09880	COG0655	NAD(P)H dehydrogenase (quinone) activity
CRN29_RS09885	COG0667	Aldo Keto reductase
CRN29_RS09895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRN29_RS09900	COG4844	belongs to the
CRN29_RS09920	COG0095	Lipoate-protein ligase
CRN29_RS09925	COG0280	phosphate acetyltransferase
CRN29_RS09930	COG3253	May function as heme-dependent peroxidase
CRN29_RS09950	COG2363	Small membrane protein
CRN29_RS09960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CRN29_RS09965	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CRN29_RS09970	COG0351	phosphomethylpyrimidine kinase
CRN29_RS09985	COG0477	Major facilitator Superfamily
CRN29_RS10000	COG0183	Belongs to the thiolase family
CRN29_RS10005	COG0318	PFAM AMP-dependent synthetase and ligase
CRN29_RS10020	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CRN29_RS10025	COG0363	glucosamine-6-phosphate deaminase activity
CRN29_RS10030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CRN29_RS10035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CRN29_RS10045	COG2271	Major facilitator Superfamily
CRN29_RS10050	COG0438	transferase activity, transferring glycosyl groups
CRN29_RS10055	COG0431	NADPH-dependent FMN reductase
CRN29_RS10060	COG0561	phosphatase activity
CRN29_RS10070	COG1428	Deoxynucleoside kinase
CRN29_RS10075	COG1428	Deoxynucleoside kinase
CRN29_RS10085	COG0546	phosphoglycolate phosphatase activity
CRN29_RS10105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CRN29_RS10115	COG0737	Belongs to the 5'-nucleotidase family
CRN29_RS10145	COG1473	amidohydrolase
CRN29_RS10150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CRN29_RS10155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CRN29_RS10165	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CRN29_RS10175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CRN29_RS10180	COG0085	RNA polymerase activity
CRN29_RS10185	COG2813	Specifically methylates the guanine in position
CRN29_RS10190	COG0222	ribosome binding
CRN29_RS10195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CRN29_RS10205	COG0081	regulation of translation
CRN29_RS10210	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CRN29_RS10215	COG0250	Participates in transcription elongation, termination and antitermination
CRN29_RS10220	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CRN29_RS10225	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CRN29_RS10235	COG3688	RNA-binding protein containing a PIN domain
CRN29_RS10245	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CRN29_RS10250	COG0215	cysteine-tRNA ligase activity
CRN29_RS10255	COG1045	serine acetyltransferase
CRN29_RS10260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CRN29_RS10265	COG4956	integral membrane protein (PIN domain superfamily)
CRN29_RS10270	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CRN29_RS10275	COG0542	response to heat
CRN29_RS10280	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CRN29_RS10285	COG3880	PFAM UvrB UvrC protein
CRN29_RS10290	COG4463	regulation of RNA biosynthetic process
CRN29_RS10295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CRN29_RS10300	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CRN29_RS10305	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CRN29_RS10310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRN29_RS10395	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CRN29_RS10400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CRN29_RS10405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CRN29_RS10415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CRN29_RS10420	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CRN29_RS10425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CRN29_RS10430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CRN29_RS10435	COG0037	tRNA processing
CRN29_RS10440	COG1098	S1 RNA binding domain
CRN29_RS10450	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CRN29_RS10455	COG3956	TIGRFAM MazG family protein
CRN29_RS10460	COG2244	polysaccharide biosynthetic process
CRN29_RS10465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CRN29_RS10475	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CRN29_RS10480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CRN29_RS10485	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CRN29_RS10490	COG2088	sporulation resulting in formation of a cellular spore
CRN29_RS10495	COG0251	oxidation-reduction process
CRN29_RS10500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CRN29_RS10505	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CRN29_RS10510	COG4466	Protein conserved in bacteria
CRN29_RS10515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CRN29_RS10520	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CRN29_RS10525	COG0084	hydrolase, TatD family'
CRN29_RS10530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRN29_RS10530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRN29_RS10535	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CRN29_RS10540	COG2827	Endonuclease containing a URI domain
CRN29_RS10545	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CRN29_RS10550	COG4467	Involved in initiation control of chromosome replication
CRN29_RS10555	COG1774	PSP1 C-terminal conserved region
CRN29_RS10560	COG0470	DNA polymerase III
CRN29_RS10565	COG3870	Protein conserved in bacteria
CRN29_RS10570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CRN29_RS10575	COG1982	Orn Lys Arg decarboxylase major
CRN29_RS10600	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CRN29_RS10605	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CRN29_RS10610	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CRN29_RS10630	COG0493	'glutamate synthase
CRN29_RS10635	COG0067	glutamate synthase
CRN29_RS10635	COG0070	glutamate synthase
CRN29_RS10635	COG0069	glutamate synthase activity
CRN29_RS10640	COG0583	DNA-binding transcription factor activity
CRN29_RS10675	COG3942	CHAP domain
CRN29_RS10675	COG1388	LysM domain
CRN29_RS10685	COG0626	cystathionine gamma-synthase activity
CRN29_RS10690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CRN29_RS10705	COG0733	neurotransmitter:sodium symporter activity
CRN29_RS10715	COG1647	Serine aminopeptidase, S33
CRN29_RS10740	COG5609	conserved protein (DUF2294)
CRN29_RS10745	COG3002	Belongs to the UPF0753 family
CRN29_RS10750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CRN29_RS10775	COG0523	cobalamin synthesis protein
CRN29_RS10785	COG2211	Major facilitator Superfamily
CRN29_RS10795	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CRN29_RS10825	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CRN29_RS10825	COG0519	Catalyzes the synthesis of GMP from XMP
CRN29_RS10830	COG0516	GMP reductase activity
CRN29_RS10830	COG0517	IMP dehydrogenase activity
CRN29_RS10835	COG2233	PERMEase
CRN29_RS10840	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CRN29_RS10855	COG5183	chlorophyll binding
CRN29_RS10860	COG1823	symporter activity
CRN29_RS10865	COG0778	Nitroreductase
CRN29_RS10875	COG0450	alkyl hydroperoxide reductase
CRN29_RS10880	COG3634	alkyl hydroperoxide reductase activity
CRN29_RS10895	COG0406	alpha-ribazole phosphatase activity
CRN29_RS10900	COG1280	lysine exporter protein (LysE YggA)
CRN29_RS10945	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CRN29_RS10955	COG0360	Binds together with S18 to 16S ribosomal RNA
CRN29_RS10965	COG1011	Hydrolase
CRN29_RS10990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CRN29_RS11010	COG0012	GTP binding
CRN29_RS11015	COG4481	Protein conserved in bacteria
CRN29_RS11020	COG0668	transmembrane transport
CRN29_RS11025	COG1475	DNA binding
CRN29_RS11035	COG0626	cystathionine gamma-synthase activity
CRN29_RS11040	COG0626	cystathionine gamma-synthase activity
CRN29_RS11045	COG0646	methionine synthase
CRN29_RS11045	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CRN29_RS11050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CRN29_RS11060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CRN29_RS11065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CRN29_RS11070	COG0183	Belongs to the thiolase family
CRN29_RS11090	COG1476	TRANSCRIPTIONal
CRN29_RS11100	COG1131	(ABC) transporter
CRN29_RS11110	COG2814	Major facilitator Superfamily
CRN29_RS11145	COG1136	(ABC) transporter
CRN29_RS11150	COG0577	efflux transmembrane transporter activity
CRN29_RS11185	COG0577	efflux transmembrane transporter activity
CRN29_RS11190	COG1136	(ABC) transporter
CRN29_RS11195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRN29_RS11235	COG0300	oxidoreductase activity
CRN29_RS11240	COG1475	DNA binding
CRN29_RS11245	COG0357	Ribosomal RNA small subunit methyltransferase G
CRN29_RS11250	COG0445	tRNA wobble uridine modification
CRN29_RS11255	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CRN29_RS11260	COG0594	ribonuclease P activity
CRN29_RS11270	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CRN29_RS11275	COG0592	DNA-directed DNA polymerase activity
CRN29_RS11280	COG2501	S4 domain
CRN29_RS11285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CRN29_RS11290	COG0187	DNA topoisomerase II activity
CRN29_RS11295	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CRN29_RS11300	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CRN29_RS11310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CRN29_RS11325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CRN29_RS11345	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CRN29_RS11350	COG0359	binds to the 23S rRNA
CRN29_RS11355	COG0305	Participates in initiation and elongation during chromosome replication
CRN29_RS11360	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CRN29_RS11375	COG0745	RESPONSE REGULATOR receiver
CRN29_RS11380	COG5002	protein histidine kinase activity
CRN29_RS11385	COG4863	YycH protein
CRN29_RS11395	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CRN29_RS11400	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CRN29_RS11440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRN29_RS11445	COG1263	PTS System
CRN29_RS11445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRN29_RS11450	COG0366	Alpha amylase catalytic
CRN29_RS11455	COG2188	Transcriptional regulator
CRN29_RS11550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CRN29_RS11570	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CRN29_RS11575	COG1755	Isoprenylcysteine carboxyl methyltransferase
CRN29_RS11580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CRN29_RS11590	COG1136	(ABC) transporter
CRN29_RS11625	COG0745	RESPONSE REGULATOR receiver
CRN29_RS11630	COG2205	protein histidine kinase activity
CRN29_RS11640	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CRN29_RS11645	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CRN29_RS11675	COG1174	glycine betaine transport
CRN29_RS11690	COG1114	Component of the transport system for branched-chain amino acids
CRN29_RS11695	COG1288	antiporter activity
CRN29_RS11700	COG0549	Belongs to the carbamate kinase family
CRN29_RS11715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CRN29_RS11720	COG2814	Major facilitator Superfamily
CRN29_RS11740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CRN29_RS11760	COG2814	Major facilitator Superfamily
CRN29_RS11770	COG1028	Short-chain dehydrogenase reductase Sdr
CRN29_RS11795	COG2814	Major facilitator Superfamily
CRN29_RS11825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CRN29_RS11830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CRN29_RS11840	COG2235	arginine
CRN29_RS11870	COG1757	Na H antiporter
CRN29_RS11905	COG3682	Transcriptional regulator
CRN29_RS11930	COG1230	cation diffusion facilitator family transporter
CRN29_RS11940	COG1937	Protein conserved in bacteria
CRN29_RS11945	COG2217	Heavy metal translocating P-type atpase
CRN29_RS11990	COG1192	Involved in chromosome partitioning
CRN29_RS12010	COG3391	amine dehydrogenase activity
CRN29_RS12015	COG0201	protein transport
CRN29_RS12025	COG1073	alpha beta
CRN29_RS12035	COG0653	protein targeting
CRN29_RS12040	COG0438	transferase activity, transferring glycosyl groups
CRN29_RS12050	COG2814	Major facilitator Superfamily
CRN29_RS12055	COG0640	Transcriptional regulator