locus-tag	class	description
JMUB0001_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JMUB0001_RS00010	COG0592	DNA-directed DNA polymerase activity
JMUB0001_RS00015	COG2501	S4 domain
JMUB0001_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JMUB0001_RS00025	COG0187	DNA topoisomerase II activity
JMUB0001_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JMUB0001_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JMUB0001_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JMUB0001_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JMUB0001_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JMUB0001_RS00075	COG0359	binds to the 23S rRNA
JMUB0001_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
JMUB0001_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JMUB0001_RS00100	COG0745	RESPONSE REGULATOR receiver
JMUB0001_RS00105	COG5002	protein histidine kinase activity
JMUB0001_RS00110	COG4863	YycH protein
JMUB0001_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JMUB0001_RS00125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JMUB0001_RS00185	COG3425	synthase
JMUB0001_RS00195	COG0584	glycerophosphoryl diester phosphodiesterase
JMUB0001_RS00200	COG2030	dehydratase
JMUB0001_RS00225	COG1940	carbohydrate kinase activity
JMUB0001_RS00225	COG1846	Transcriptional regulator
JMUB0001_RS00235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMUB0001_RS00240	COG2210	Belongs to the sulfur carrier protein TusA family
JMUB0001_RS00245	COG1937	Protein conserved in bacteria
JMUB0001_RS00250	COG0730	response to heat
JMUB0001_RS00260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JMUB0001_RS00300	COG2003	Belongs to the UPF0758 family
JMUB0001_RS00375	COG0202	RNA polymerase activity
JMUB0001_RS00385	COG0513	Belongs to the DEAD box helicase family
JMUB0001_RS00395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JMUB0001_RS00400	COG1755	Isoprenylcysteine carboxyl methyltransferase
JMUB0001_RS00405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JMUB0001_RS00415	COG1136	(ABC) transporter
JMUB0001_RS00445	COG0745	RESPONSE REGULATOR receiver
JMUB0001_RS00450	COG2205	protein histidine kinase activity
JMUB0001_RS00460	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JMUB0001_RS00465	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JMUB0001_RS00500	COG0601	transmembrane transport
JMUB0001_RS00510	COG0444	Belongs to the ABC transporter superfamily
JMUB0001_RS00535	COG3246	L-lysine catabolic process to acetate
JMUB0001_RS00540	COG1250	3-hydroxyacyl-CoA dehydrogenase
JMUB0001_RS00565	COG1174	glycine betaine transport
JMUB0001_RS00580	COG1114	Component of the transport system for branched-chain amino acids
JMUB0001_RS00585	COG1288	antiporter activity
JMUB0001_RS00590	COG0549	Belongs to the carbamate kinase family
JMUB0001_RS00605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMUB0001_RS00610	COG0477	Major facilitator Superfamily
JMUB0001_RS00635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JMUB0001_RS00655	COG2814	Major facilitator Superfamily
JMUB0001_RS00665	COG1028	Short-chain dehydrogenase reductase Sdr
JMUB0001_RS00690	COG2814	Major facilitator Superfamily
JMUB0001_RS00715	COG2814	Major facilitator Superfamily
JMUB0001_RS00720	COG0583	DNA-binding transcription factor activity
JMUB0001_RS00725	COG2318	DinB family
JMUB0001_RS00730	COG2311	Membrane
JMUB0001_RS00735	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
JMUB0001_RS00745	COG0471	metal ion transport
JMUB0001_RS00760	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JMUB0001_RS00765	COG1054	Belongs to the UPF0176 family
JMUB0001_RS00770	COG3386	PFAM SMP-30 Gluconolaconase
JMUB0001_RS00775	COG2353	YceI-like domain
JMUB0001_RS00785	COG0579	oxidoreductase
JMUB0001_RS00805	COG1686	Belongs to the peptidase S11 family
JMUB0001_RS00840	COG0726	polysaccharide deacetylase
JMUB0001_RS00880	COG0737	Belongs to the 5'-nucleotidase family
JMUB0001_RS00895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JMUB0001_RS00900	COG3639	organic phosphonate transmembrane transporter activity
JMUB0001_RS00910	COG0702	epimerase
JMUB0001_RS00925	COG0201	protein transport
JMUB0001_RS00935	COG1073	alpha beta
JMUB0001_RS00945	COG0653	protein targeting
JMUB0001_RS00955	COG0438	transferase activity, transferring glycosyl groups
JMUB0001_RS00990	COG2814	Major facilitator Superfamily
JMUB0001_RS00995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JMUB0001_RS01000	COG0604	alcohol dehydrogenase
JMUB0001_RS01015	COG2113	Glycine betaine
JMUB0001_RS01020	COG2409	Drug exporters of the RND superfamily
JMUB0001_RS01030	COG0583	DNA-binding transcription factor activity
JMUB0001_RS01035	COG3842	ATPase activity
JMUB0001_RS01040	COG1840	ABC-type Fe3 transport system, periplasmic component
JMUB0001_RS01050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JMUB0001_RS01055	COG1764	response to oxidative stress
JMUB0001_RS01070	COG3942	CHAP domain
JMUB0001_RS01070	COG1705	Flagellar rod assembly protein muramidase FlgJ
JMUB0001_RS01070	COG1705	Flagellar rod assembly protein muramidase FlgJ
JMUB0001_RS01070	COG3942	CHAP domain
JMUB0001_RS01080	COG1482	cell wall glycoprotein biosynthetic process
JMUB0001_RS01085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMUB0001_RS01085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMUB0001_RS01085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMUB0001_RS01090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMUB0001_RS01090	COG3711	transcriptional antiterminator
JMUB0001_RS01125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMUB0001_RS01165	COG2235	arginine
JMUB0001_RS01170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JMUB0001_RS01185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JMUB0001_RS01200	COG2843	Capsule synthesis protein
JMUB0001_RS01220	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JMUB0001_RS01225	COG3961	Belongs to the TPP enzyme family
JMUB0001_RS01230	COG1846	Transcriptional regulator
JMUB0001_RS01245	COG4195	phage-related replication protein
JMUB0001_RS01255	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JMUB0001_RS01265	COG0702	epimerase
JMUB0001_RS01270	COG1785	Belongs to the alkaline phosphatase family
JMUB0001_RS01275	COG0745	RESPONSE REGULATOR receiver
JMUB0001_RS01280	COG2205	protein histidine kinase activity
JMUB0001_RS01285	COG1136	(ABC) transporter
JMUB0001_RS01300	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JMUB0001_RS01325	COG0386	Belongs to the glutathione peroxidase family
JMUB0001_RS01330	COG0175	sulfate reduction
JMUB0001_RS01335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JMUB0001_RS01340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JMUB0001_RS01355	COG0730	response to heat
JMUB0001_RS01360	COG2046	Belongs to the sulfate adenylyltransferase family
JMUB0001_RS01365	COG0529	Catalyzes the synthesis of activated sulfate
JMUB0001_RS01370	COG2851	Citrate transporter
JMUB0001_RS01385	COG1328	CTP reductase activity
JMUB0001_RS01390	COG0602	queuosine metabolic process
JMUB0001_RS01395	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JMUB0001_RS01405	COG1510	regulation of RNA biosynthetic process
JMUB0001_RS01410	COG1012	belongs to the aldehyde dehydrogenase family
JMUB0001_RS01415	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JMUB0001_RS01420	COG1473	amidohydrolase
JMUB0001_RS01445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JMUB0001_RS01450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JMUB0001_RS01450	COG0574	Belongs to the PEP-utilizing enzyme family
JMUB0001_RS01455	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JMUB0001_RS01460	COG0579	oxidoreductase
JMUB0001_RS01480	COG3588	fructose-bisphosphate aldolase
JMUB0001_RS01485	COG0446	pyridine nucleotide-disulphide oxidoreductase
JMUB0001_RS01510	COG0531	amino acid
JMUB0001_RS01520	COG0583	DNA-binding transcription factor activity
JMUB0001_RS01525	COG0039	L-malate dehydrogenase activity
JMUB0001_RS01530	COG0028	Belongs to the TPP enzyme family
JMUB0001_RS01535	COG3527	Alpha-acetolactate decarboxylase
JMUB0001_RS01545	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JMUB0001_RS01550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JMUB0001_RS01565	COG4640	response to antibiotic
JMUB0001_RS01590	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JMUB0001_RS01600	COG0167	dihydroorotate dehydrogenase activity
JMUB0001_RS01605	COG3001	Fructosamine kinase
JMUB0001_RS01620	COG0596	Alpha beta hydrolase
JMUB0001_RS01630	COG1028	Short-chain dehydrogenase reductase Sdr
JMUB0001_RS01655	COG1113	amino acid transport
JMUB0001_RS01670	COG2326	polyphosphate kinase activity
JMUB0001_RS01675	COG0741	lytic transglycosylase activity
JMUB0001_RS01710	COG0436	Aminotransferase
JMUB0001_RS01725	COG2608	mercury ion transmembrane transporter activity
JMUB0001_RS01730	COG2217	Heavy metal translocating P-type atpase
JMUB0001_RS01740	COG1028	Short-chain dehydrogenase reductase Sdr
JMUB0001_RS01755	COG1012	belongs to the aldehyde dehydrogenase family
JMUB0001_RS01790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JMUB0001_RS01795	COG3425	synthase
JMUB0001_RS01815	COG0583	DNA-binding transcription factor activity
JMUB0001_RS01820	COG1380	Effector of murein hydrolase LrgA
JMUB0001_RS01825	COG1346	cytolysis
JMUB0001_RS01830	COG0028	Belongs to the TPP enzyme family
JMUB0001_RS01840	COG1266	CAAX protease self-immunity
JMUB0001_RS01855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JMUB0001_RS01860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMUB0001_RS01870	COG0697	spore germination
JMUB0001_RS01875	COG2207	Transcriptional regulator
JMUB0001_RS01875	COG1917	Cupin 2, conserved barrel domain protein
JMUB0001_RS01885	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JMUB0001_RS01895	COG2843	Capsule synthesis protein
JMUB0001_RS01910	COG4975	Glucose uptake
JMUB0001_RS01915	COG1869	D-ribose catabolic process
JMUB0001_RS01925	COG1070	Carbohydrate kinase
JMUB0001_RS01940	COG1760	l-serine dehydratase
JMUB0001_RS01945	COG1760	l-serine dehydratase
JMUB0001_RS01955	COG1247	-acetyltransferase
JMUB0001_RS01960	COG3764	Sortase (surface protein transpeptidase)
JMUB0001_RS01965	COG0561	phosphatase activity
JMUB0001_RS01975	COG0778	Nitroreductase
JMUB0001_RS01980	COG1012	belongs to the aldehyde dehydrogenase family
JMUB0001_RS01985	COG2514	catechol 2,3-dioxygenase activity
JMUB0001_RS02000	COG1012	belongs to the aldehyde dehydrogenase family
JMUB0001_RS02005	COG3949	Membrane
JMUB0001_RS02015	COG1476	TRANSCRIPTIONal
JMUB0001_RS02025	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JMUB0001_RS02030	COG0586	Pfam SNARE associated Golgi protein
JMUB0001_RS02040	COG2022	thiamine diphosphate biosynthetic process
JMUB0001_RS02050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JMUB0001_RS02060	COG2271	Major facilitator Superfamily
JMUB0001_RS02075	COG4876	unkown
JMUB0001_RS02080	COG2357	RelA SpoT domain protein
JMUB0001_RS02090	COG1802	Transcriptional regulator
JMUB0001_RS02095	COG1070	Carbohydrate kinase
JMUB0001_RS02100	COG2610	gluconate transmembrane transporter activity
JMUB0001_RS02105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JMUB0001_RS02110	COG1215	transferase activity, transferring glycosyl groups
JMUB0001_RS02125	COG4221	oxidoreductase activity
JMUB0001_RS02130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JMUB0001_RS02135	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JMUB0001_RS02145	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JMUB0001_RS02150	COG1028	Short-chain dehydrogenase reductase Sdr
JMUB0001_RS02160	COG1363	Peptidase, m42
JMUB0001_RS02165	COG4808	Protein conserved in bacteria
JMUB0001_RS02170	COG0069	glutamate synthase activity
JMUB0001_RS02185	COG4619	ABC transporter
JMUB0001_RS02190	COG0390	transport system, permease component
JMUB0001_RS02195	COG2814	Major facilitator Superfamily
JMUB0001_RS02200	COG2272	Belongs to the type-B carboxylesterase lipase family
JMUB0001_RS02205	COG0531	amino acid
JMUB0001_RS02210	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JMUB0001_RS02215	COG1063	alcohol dehydrogenase
JMUB0001_RS02235	COG1174	glycine betaine transport
JMUB0001_RS02240	COG1346	cytolysis
JMUB0001_RS02245	COG1380	Effector of murein hydrolase LrgA
JMUB0001_RS02255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JMUB0001_RS02270	COG0706	membrane insertase activity
JMUB0001_RS02280	COG0531	amino acid
JMUB0001_RS02290	COG1113	amino acid transport
JMUB0001_RS02310	COG2814	Major facilitator Superfamily
JMUB0001_RS02320	COG1929	Belongs to the glycerate kinase type-1 family
JMUB0001_RS02335	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JMUB0001_RS02340	COG0741	lytic transglycosylase activity
JMUB0001_RS02345	COG0588	phosphoglycerate mutase activity
JMUB0001_RS02355	COG2814	Major facilitator Superfamily
JMUB0001_RS02360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JMUB0001_RS02365	COG0765	amino acid transport
JMUB0001_RS02370	COG1126	abc transporter atp-binding protein
JMUB0001_RS02380	COG2348	transferase activity, transferring amino-acyl groups
JMUB0001_RS02415	COG0454	-acetyltransferase
JMUB0001_RS02420	COG0747	negative chemotaxis
JMUB0001_RS02430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JMUB0001_RS02435	COG2146	nitrite reductase [NAD(P)H] activity
JMUB0001_RS02445	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JMUB0001_RS02450	COG1140	nitrate reductase beta subunit
JMUB0001_RS02460	COG2181	nitrate reductase activity
JMUB0001_RS02470	COG4585	Histidine kinase
JMUB0001_RS02475	COG2197	response regulator
JMUB0001_RS02480	COG2223	nitrite transmembrane transporter activity
JMUB0001_RS02495	COG0778	Nitroreductase
JMUB0001_RS02515	COG3871	stress protein (general stress protein 26)
JMUB0001_RS02520	COG4753	response regulator
JMUB0001_RS02520	COG2207	Transcriptional regulator
JMUB0001_RS02530	COG1263	PTS System
JMUB0001_RS02530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMUB0001_RS02565	COG0492	ferredoxin-NADP+ reductase activity
JMUB0001_RS02575	COG0604	alcohol dehydrogenase
JMUB0001_RS02580	COG2822	iron ion transport
JMUB0001_RS02585	COG2837	iron assimilation
JMUB0001_RS02590	COG0672	)-iron permease
JMUB0001_RS02595	COG0805	protein transport
JMUB0001_RS02600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JMUB0001_RS02610	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMUB0001_RS02610	COG0463	Glycosyl transferase, family 2
JMUB0001_RS02620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMUB0001_RS02625	COG1620	l-lactate permease
JMUB0001_RS02635	COG0579	oxidoreductase
JMUB0001_RS02640	COG3850	Histidine kinase
JMUB0001_RS02640	COG5002	protein histidine kinase activity
JMUB0001_RS02645	COG0745	RESPONSE REGULATOR receiver
JMUB0001_RS02650	COG0577	efflux transmembrane transporter activity
JMUB0001_RS02655	COG1136	(ABC) transporter
JMUB0001_RS02670	COG4640	response to antibiotic
JMUB0001_RS02685	COG1566	PFAM secretion protein HlyD family protein
JMUB0001_RS02690	COG2814	Major facilitator Superfamily
JMUB0001_RS02715	COG0598	Magnesium transport protein CorA
JMUB0001_RS02720	COG1304	FMN binding
JMUB0001_RS02725	COG0786	glutamate:sodium symporter activity
JMUB0001_RS02745	COG2094	Belongs to the DNA glycosylase MPG family
JMUB0001_RS02750	COG3152	Membrane
JMUB0001_RS02765	COG1069	ribulokinase activity
JMUB0001_RS02770	COG4152	abc transporter atp-binding protein
JMUB0001_RS02780	COG1742	UPF0060 membrane protein
JMUB0001_RS02790	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JMUB0001_RS02795	COG1266	CAAX protease self-immunity
JMUB0001_RS02800	COG0010	Belongs to the arginase family
JMUB0001_RS02805	COG0583	DNA-binding transcription factor activity
JMUB0001_RS02820	COG0659	secondary active sulfate transmembrane transporter activity
JMUB0001_RS02825	COG1473	amidohydrolase
JMUB0001_RS02830	COG1028	Short-chain dehydrogenase reductase Sdr
JMUB0001_RS02850	COG1737	Transcriptional regulator
JMUB0001_RS02855	COG1263	PTS System
JMUB0001_RS02855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMUB0001_RS02865	COG0385	Bile acid
JMUB0001_RS02870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JMUB0001_RS02890	COG1113	amino acid transport
JMUB0001_RS02900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMUB0001_RS02900	COG1263	PTS System
JMUB0001_RS02905	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JMUB0001_RS02935	COG1316	TRANSCRIPTIONal
JMUB0001_RS02965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMUB0001_RS02970	COG2076	Multidrug Resistance protein
JMUB0001_RS02975	COG2076	Multidrug Resistance protein
JMUB0001_RS02980	COG3942	CHAP domain
JMUB0001_RS02995	COG1757	Na H antiporter
JMUB0001_RS03000	COG3942	CHAP domain
JMUB0001_RS03025	COG0829	nickel cation binding
JMUB0001_RS03040	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JMUB0001_RS03045	COG0804	urea catabolic process
JMUB0001_RS03055	COG0831	urea catabolic process
JMUB0001_RS03060	COG4413	Urea transporter
JMUB0001_RS03065	COG1960	acyl-CoA dehydrogenase activity
JMUB0001_RS03070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JMUB0001_RS03080	COG1268	BioY protein
JMUB0001_RS03095	COG0725	ABC transporter, periplasmic molybdate-binding protein
JMUB0001_RS03100	COG4149	molybdate abc transporter
JMUB0001_RS03105	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JMUB0001_RS03110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JMUB0001_RS03115	COG0521	Mo-molybdopterin cofactor biosynthetic process
JMUB0001_RS03120	COG0315	cyclic pyranopterin monophosphate synthase activity
JMUB0001_RS03125	COG0303	'Molybdopterin
JMUB0001_RS03130	COG1763	Mo-molybdopterin cofactor biosynthetic process
JMUB0001_RS03145	COG0746	molybdenum cofactor guanylyltransferase activity
JMUB0001_RS03150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JMUB0001_RS03160	COG2814	Major facilitator Superfamily
JMUB0001_RS03180	COG2348	transferase activity, transferring amino-acyl groups
JMUB0001_RS03185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JMUB0001_RS03210	COG4975	Glucose uptake
JMUB0001_RS03220	COG0551	DNA topoisomerase type I activity
JMUB0001_RS03220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMUB0001_RS03225	COG2252	PERMEase
JMUB0001_RS03240	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JMUB0001_RS03245	COG0088	Forms part of the polypeptide exit tunnel
JMUB0001_RS03250	COG0089	rRNA binding
JMUB0001_RS03255	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JMUB0001_RS03260	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JMUB0001_RS03270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JMUB0001_RS03275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JMUB0001_RS03285	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JMUB0001_RS03290	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JMUB0001_RS03295	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JMUB0001_RS03300	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JMUB0001_RS03305	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JMUB0001_RS03310	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JMUB0001_RS03315	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JMUB0001_RS03320	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JMUB0001_RS03325	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JMUB0001_RS03330	COG1841	ribosomal large subunit assembly
JMUB0001_RS03335	COG0200	Binds to the 23S rRNA
JMUB0001_RS03340	COG0201	protein transport
JMUB0001_RS03345	COG0563	adenylate kinase activity
JMUB0001_RS03350	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JMUB0001_RS03355	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JMUB0001_RS03360	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JMUB0001_RS03370	COG0202	RNA polymerase activity
JMUB0001_RS03375	COG0203	ribosomal protein L17
JMUB0001_RS03380	COG1122	ATPase activity
JMUB0001_RS03385	COG1122	ATPase activity
JMUB0001_RS03395	COG0101	tRNA pseudouridine synthase activity
JMUB0001_RS03400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JMUB0001_RS03410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JMUB0001_RS03415	COG1349	DNA-binding transcription factor activity
JMUB0001_RS03420	COG0698	ribose 5-phosphate isomerase
JMUB0001_RS03445	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMUB0001_RS03445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JMUB0001_RS03460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMUB0001_RS03465	COG2130	NADP-dependent
JMUB0001_RS03475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JMUB0001_RS03490	COG1302	Protein conserved in bacteria
JMUB0001_RS03495	COG4264	IucA IucC family
JMUB0001_RS03500	COG2814	Major facilitator Superfamily
JMUB0001_RS03505	COG4264	IucA IucC family
JMUB0001_RS03510	COG3457	Alanine racemase
JMUB0001_RS03515	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JMUB0001_RS03520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMUB0001_RS03525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMUB0001_RS03530	COG3314	Sporulation integral membrane protein YlbJ
JMUB0001_RS03535	COG2329	Antibiotic biosynthesis monooxygenase
JMUB0001_RS03545	COG1988	membrane-bound metal-dependent
JMUB0001_RS03550	COG4284	Utp--glucose-1-phosphate uridylyltransferase
JMUB0001_RS03555	COG1272	protein, Hemolysin III
JMUB0001_RS03570	COG2814	Major facilitator Superfamily
JMUB0001_RS03575	COG0489	protein tyrosine kinase activity
JMUB0001_RS03630	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JMUB0001_RS03640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMUB0001_RS03655	COG3711	transcriptional antiterminator
JMUB0001_RS03665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JMUB0001_RS03670	COG0561	phosphatase activity
JMUB0001_RS03690	COG0640	Transcriptional regulator
JMUB0001_RS03695	COG0702	epimerase
JMUB0001_RS03700	COG1482	cell wall glycoprotein biosynthetic process
JMUB0001_RS03720	COG0783	Belongs to the Dps family
JMUB0001_RS03725	COG0813	purine-nucleoside phosphorylase activity
JMUB0001_RS03730	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JMUB0001_RS03735	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JMUB0001_RS03740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JMUB0001_RS03755	COG1854	S-ribosylhomocysteine lyase activity
JMUB0001_RS03775	COG5146	pantothenate kinase activity
JMUB0001_RS03785	COG3343	RNA polymerase activity
JMUB0001_RS03790	COG0504	CTP synthase activity
JMUB0001_RS03800	COG0191	fructose-bisphosphate aldolase activity
JMUB0001_RS03805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JMUB0001_RS03815	COG1012	belongs to the aldehyde dehydrogenase family
JMUB0001_RS03820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JMUB0001_RS03825	COG0254	rRNA binding
JMUB0001_RS03830	COG1435	thymidine kinase activity
JMUB0001_RS03840	COG2890	protein-(glutamine-N5) methyltransferase activity
JMUB0001_RS03845	COG0009	L-threonylcarbamoyladenylate synthase
JMUB0001_RS03850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JMUB0001_RS03855	COG4475	Protein of unknown function (DUF436)
JMUB0001_RS03860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JMUB0001_RS03865	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JMUB0001_RS03870	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JMUB0001_RS03880	COG0356	it plays a direct role in the translocation of protons across the membrane
JMUB0001_RS03890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JMUB0001_RS03895	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JMUB0001_RS03900	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JMUB0001_RS03905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JMUB0001_RS03910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JMUB0001_RS03915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JMUB0001_RS03925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JMUB0001_RS03930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JMUB0001_RS03940	COG0629	single-stranded DNA binding
JMUB0001_RS03945	COG1388	LysM domain
JMUB0001_RS03950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JMUB0001_RS03960	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JMUB0001_RS03965	COG0352	thiamine-phosphate diphosphorylase activity
JMUB0001_RS03970	COG0706	membrane insertase activity
JMUB0001_RS03975	COG1418	mRNA catabolic process
JMUB0001_RS03980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JMUB0001_RS03985	COG1937	Protein conserved in bacteria
JMUB0001_RS04000	COG0772	Belongs to the SEDS family
JMUB0001_RS04005	COG1181	Belongs to the D-alanine--D-alanine ligase family
JMUB0001_RS04010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JMUB0001_RS04015	COG0513	Belongs to the DEAD box helicase family
JMUB0001_RS04030	COG3402	PFAM membrane-flanked domain
JMUB0001_RS04040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JMUB0001_RS04050	COG2337	Toxic component of a toxin-antitoxin (TA) module
JMUB0001_RS04055	COG2208	phosphoserine phosphatase activity
JMUB0001_RS04070	COG1191	sigma factor activity
JMUB0001_RS04075	COG2183	response to ionizing radiation
JMUB0001_RS04080	COG3091	SprT-like family
JMUB0001_RS04115	COG0066	3-isopropylmalate dehydratase activity
JMUB0001_RS04120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JMUB0001_RS04125	COG0473	3-isopropylmalate dehydrogenase activity
JMUB0001_RS04135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JMUB0001_RS04145	COG0028	Belongs to the TPP enzyme family
JMUB0001_RS04150	COG0129	dihydroxy-acid dehydratase activity
JMUB0001_RS04155	COG0802	atpase or kinase
JMUB0001_RS04160	COG1214	PFAM Peptidase M22, glycoprotease
JMUB0001_RS04165	COG0456	acetyltransferase
JMUB0001_RS04170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JMUB0001_RS04175	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JMUB0001_RS04180	COG0488	(ABC) transporter
JMUB0001_RS04185	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JMUB0001_RS04195	COG2391	methyltransferase activity
JMUB0001_RS04200	COG0425	Belongs to the sulfur carrier protein TusA family
JMUB0001_RS04205	COG0004	ammonium transporteR
JMUB0001_RS04210	COG1609	Transcriptional regulator
JMUB0001_RS04215	COG1621	beta-fructofuranosidase activity
JMUB0001_RS04220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JMUB0001_RS04225	COG3279	Response regulator of the LytR AlgR family
JMUB0001_RS04230	COG3290	protein histidine kinase activity
JMUB0001_RS04265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JMUB0001_RS04270	COG0459	protein refolding
JMUB0001_RS04300	COG1725	Transcriptional regulator
JMUB0001_RS04315	COG1131	(ABC) transporter
JMUB0001_RS04360	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JMUB0001_RS04365	COG2706	6-phosphogluconolactonase activity
JMUB0001_RS04370	COG1012	belongs to the aldehyde dehydrogenase family
JMUB0001_RS04375	COG1227	inorganic diphosphatase activity
JMUB0001_RS04380	COG1335	isochorismatase
JMUB0001_RS04390	COG0077	Prephenate dehydratase
JMUB0001_RS04400	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JMUB0001_RS04405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JMUB0001_RS04410	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JMUB0001_RS04420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JMUB0001_RS04425	COG4496	protein, YerC YecD
JMUB0001_RS04430	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JMUB0001_RS04435	COG0210	DNA helicase
JMUB0001_RS04440	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JMUB0001_RS04450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JMUB0001_RS04455	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JMUB0001_RS04460	COG0154	amidase activity
JMUB0001_RS04465	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JMUB0001_RS04470	COG1597	lipid kinase activity
JMUB0001_RS04475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JMUB0001_RS04495	COG1528	Iron-storage protein
JMUB0001_RS04515	COG4129	membrane
JMUB0001_RS04520	COG0024	Methionine aminopeptidase
JMUB0001_RS04540	COG2197	response regulator
JMUB0001_RS04545	COG1295	ribonuclease BN
JMUB0001_RS04555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JMUB0001_RS04560	COG4840	Belongs to the UPF0435 family
JMUB0001_RS04565	COG2309	aminopeptidase activity
JMUB0001_RS04570	COG1607	acyl-coa hydrolase
JMUB0001_RS04575	COG0535	radical SAM domain protein
JMUB0001_RS04585	COG0693	protein deglycase activity
JMUB0001_RS04590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JMUB0001_RS04595	COG2137	regulation of response to DNA damage stimulus
JMUB0001_RS04605	COG1388	LysM domain
JMUB0001_RS04605	COG1134	teichoic acid transport
JMUB0001_RS04615	COG1988	membrane-bound metal-dependent
JMUB0001_RS04625	COG3557	Belongs to the UPF0374 family
JMUB0001_RS04635	COG4129	membrane
JMUB0001_RS04640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JMUB0001_RS04645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JMUB0001_RS04650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMUB0001_RS04655	COG0735	belongs to the Fur family
JMUB0001_RS04825	COG0765	amino acid transport
JMUB0001_RS04830	COG1126	abc transporter atp-binding protein
JMUB0001_RS04835	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JMUB0001_RS04845	COG0363	glucosamine-6-phosphate deaminase activity
JMUB0001_RS04860	COG0114	fumarate hydratase activity
JMUB0001_RS04865	COG0564	pseudouridine synthase activity
JMUB0001_RS04870	COG2203	Gaf domain
JMUB0001_RS04870	COG4585	Histidine kinase
JMUB0001_RS04875	COG2197	response regulator
JMUB0001_RS04885	COG4399	Belongs to the UPF0754 family
JMUB0001_RS04890	COG3679	Belongs to the UPF0342 family
JMUB0001_RS04895	COG0420	3'-5' exonuclease activity
JMUB0001_RS04905	COG3481	metal-dependent phosphohydrolase, HD sub domain
JMUB0001_RS04915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JMUB0001_RS04930	COG0537	adenosine 5'-monophosphoramidase activity
JMUB0001_RS04935	COG1131	(ABC) transporter
JMUB0001_RS04940	COG4473	ABC transporter
JMUB0001_RS04945	COG2329	Antibiotic biosynthesis monooxygenase
JMUB0001_RS04950	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JMUB0001_RS04955	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JMUB0001_RS04960	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JMUB0001_RS05010	COG0318	PFAM AMP-dependent synthetase and ligase
JMUB0001_RS05025	COG0494	nUDIX hydrolase
JMUB0001_RS05030	COG1506	peptidase
JMUB0001_RS05040	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JMUB0001_RS05050	COG0656	L-ascorbic acid biosynthetic process
JMUB0001_RS05055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JMUB0001_RS05060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JMUB0001_RS05070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JMUB0001_RS05085	COG1595	DNA-templated transcription, initiation
JMUB0001_RS05095	COG4193	domain, Protein
JMUB0001_RS05095	COG3266	domain, Protein
JMUB0001_RS05095	COG5632	N-Acetylmuramoyl-L-alanine amidase
JMUB0001_RS05105	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JMUB0001_RS05105	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JMUB0001_RS05115	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JMUB0001_RS05115	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JMUB0001_RS05120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JMUB0001_RS05125	COG0506	proline dehydrogenase activity
JMUB0001_RS05130	COG2267	carboxylic ester hydrolase activity
JMUB0001_RS05140	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JMUB0001_RS05145	COG1242	4 iron, 4 sulfur cluster binding
JMUB0001_RS05150	COG2814	Major facilitator Superfamily
JMUB0001_RS05155	COG0495	leucyl-tRNA aminoacylation
JMUB0001_RS05160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JMUB0001_RS05170	COG2081	HI0933 family
JMUB0001_RS05175	COG2244	polysaccharide biosynthetic process
JMUB0001_RS05180	COG1187	pseudouridine synthase activity
JMUB0001_RS05195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JMUB0001_RS05200	COG0510	thiamine kinase activity
JMUB0001_RS05205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JMUB0001_RS05210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMUB0001_RS05220	COG1363	Peptidase, m42
JMUB0001_RS05225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JMUB0001_RS05230	COG4848	Belongs to the UPF0354 family
JMUB0001_RS05235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMUB0001_RS05240	COG1674	ftsk spoiiie
JMUB0001_RS05245	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JMUB0001_RS05250	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JMUB0001_RS05260	COG1605	Chorismate mutase
JMUB0001_RS05260	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JMUB0001_RS05265	COG1609	Transcriptional regulator
JMUB0001_RS05275	COG0454	-acetyltransferase
JMUB0001_RS05280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JMUB0001_RS05285	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JMUB0001_RS05290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JMUB0001_RS05295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JMUB0001_RS05305	COG2814	Major facilitator Superfamily
JMUB0001_RS05310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JMUB0001_RS05315	COG0204	Acyl-transferase
JMUB0001_RS05320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JMUB0001_RS05320	COG1263	PTS System
JMUB0001_RS05330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JMUB0001_RS05340	COG1764	response to oxidative stress
JMUB0001_RS05345	COG0584	glycerophosphoryl diester phosphodiesterase
JMUB0001_RS05350	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JMUB0001_RS05360	COG1956	GAF domain-containing protein
JMUB0001_RS05365	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JMUB0001_RS05370	COG1104	cysteine desulfurase activity
JMUB0001_RS05375	COG0301	tRNA thio-modification
JMUB0001_RS05385	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JMUB0001_RS05390	COG0827	DNA restriction-modification system
JMUB0001_RS05395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JMUB0001_RS05400	COG0589	response to stress
JMUB0001_RS05410	COG0006	proline dipeptidase activity
JMUB0001_RS05415	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JMUB0001_RS05425	COG4109	DRTGG domain
JMUB0001_RS05430	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JMUB0001_RS05435	COG0587	DNA-directed DNA polymerase activity
JMUB0001_RS05440	COG0281	malic enzyme
JMUB0001_RS05445	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JMUB0001_RS05450	COG0825	malonyl-CoA metabolic process
JMUB0001_RS05455	COG0205	6-phosphofructokinase activity
JMUB0001_RS05460	COG0469	pyruvate kinase activity
JMUB0001_RS05465	COG1113	amino acid transport
JMUB0001_RS05470	COG0372	Belongs to the citrate synthase family
JMUB0001_RS05475	COG0538	isocitrate dehydrogenase activity
JMUB0001_RS05480	COG0745	RESPONSE REGULATOR receiver
JMUB0001_RS05485	COG5002	protein histidine kinase activity
JMUB0001_RS05490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMUB0001_RS05490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMUB0001_RS05500	COG0237	dephospho-CoA kinase activity
JMUB0001_RS05505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JMUB0001_RS05510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JMUB0001_RS05520	COG1484	DNA-dependent DNA replication
JMUB0001_RS05525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JMUB0001_RS05530	COG0833	amino acid
JMUB0001_RS05535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JMUB0001_RS05540	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JMUB0001_RS05545	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JMUB0001_RS05550	COG4112	unkown
JMUB0001_RS05560	COG0544	peptidyl-prolyl cis-trans isomerase activity
JMUB0001_RS05565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JMUB0001_RS05570	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JMUB0001_RS05575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JMUB0001_RS05580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JMUB0001_RS05585	COG0181	hydroxymethylbilane synthase activity
JMUB0001_RS05595	COG0113	porphobilinogen synthase activity
JMUB0001_RS05600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JMUB0001_RS05610	COG2818	Glycosylase
JMUB0001_RS05615	COG0525	valine-tRNA ligase activity
JMUB0001_RS05620	COG0285	dihydrofolate synthase activity
JMUB0001_RS05630	COG2003	Belongs to the UPF0758 family
JMUB0001_RS05670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JMUB0001_RS05710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JMUB0001_RS05715	COG2868	ribosomal protein
JMUB0001_RS05720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JMUB0001_RS05725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JMUB0001_RS05730	COG4492	Belongs to the UPF0735 family
JMUB0001_RS05735	COG0632	four-way junction helicase activity
JMUB0001_RS05740	COG2255	four-way junction helicase activity
JMUB0001_RS05745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JMUB0001_RS05755	COG1862	Preprotein translocase
JMUB0001_RS05760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JMUB0001_RS05760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JMUB0001_RS05765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JMUB0001_RS05765	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JMUB0001_RS05775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JMUB0001_RS05780	COG1490	D-aminoacyl-tRNA deacylase activity
JMUB0001_RS05785	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMUB0001_RS05795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JMUB0001_RS05805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JMUB0001_RS05810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JMUB0001_RS05815	COG1959	2 iron, 2 sulfur cluster binding
JMUB0001_RS05825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JMUB0001_RS05830	COG1104	cysteine desulfurase activity
JMUB0001_RS05835	COG0482	sulfurtransferase activity
JMUB0001_RS05845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JMUB0001_RS05850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JMUB0001_RS05855	COG4472	Bacterial protein of unknown function (DUF965)
JMUB0001_RS05860	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JMUB0001_RS05865	COG3906	Belongs to the UPF0473 family
JMUB0001_RS05875	COG0826	peptidase U32
JMUB0001_RS05880	COG0826	peptidase U32
JMUB0001_RS05885	COG0572	uridine kinase
JMUB0001_RS05890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JMUB0001_RS05895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JMUB0001_RS05900	COG1984	allophanate hydrolase subunit 2
JMUB0001_RS05905	COG0511	ligase activity, forming carbon-carbon bonds
JMUB0001_RS05910	COG0439	Biotin carboxylase
JMUB0001_RS05915	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JMUB0001_RS05920	COG1914	H( )-stimulated, divalent metal cation uptake system
JMUB0001_RS05925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JMUB0001_RS05930	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JMUB0001_RS05935	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JMUB0001_RS05945	COG1534	Rna-binding protein
JMUB0001_RS05950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JMUB0001_RS05955	COG1713	HD superfamily hydrolase involved in NAD metabolism
JMUB0001_RS05960	COG0799	negative regulation of ribosome biogenesis
JMUB0001_RS05965	COG2226	methyltransferase
JMUB0001_RS05970	COG1596	polysaccharide export
JMUB0001_RS05970	COG1555	photosystem II stabilization
JMUB0001_RS05975	COG2131	deaminase
JMUB0001_RS05985	COG1466	dna polymerase III delta subunit
JMUB0001_RS05990	COG0268	Binds directly to 16S ribosomal RNA
JMUB0001_RS05995	COG0481	GTPase activity
JMUB0001_RS06000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JMUB0001_RS06005	COG1420	regulation of RNA biosynthetic process
JMUB0001_RS06010	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JMUB0001_RS06015	COG0443	Heat shock 70 kDa protein
JMUB0001_RS06020	COG0484	heat shock protein binding
JMUB0001_RS06025	COG2264	protein methyltransferase activity
JMUB0001_RS06030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JMUB0001_RS06035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMUB0001_RS06045	COG1030	water channel activity
JMUB0001_RS06050	COG4864	UPF0365 protein
JMUB0001_RS06060	COG1702	phosphate starvation-inducible protein PhoH
JMUB0001_RS06065	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JMUB0001_RS06075	COG0295	cytidine deaminase activity
JMUB0001_RS06080	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JMUB0001_RS06085	COG1381	Involved in DNA repair and RecF pathway recombination
JMUB0001_RS06090	COG0423	glycine-tRNA ligase activity
JMUB0001_RS06095	COG0517	IMP dehydrogenase activity
JMUB0001_RS06100	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JMUB0001_RS06105	COG0358	DNA primase activity
JMUB0001_RS06110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JMUB0001_RS06115	COG2384	SAM-dependent methyltransferase
JMUB0001_RS06120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JMUB0001_RS06125	COG0513	Belongs to the DEAD box helicase family
JMUB0001_RS06130	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JMUB0001_RS06135	COG1121	(ABC) transporter
JMUB0001_RS06140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JMUB0001_RS06155	COG0768	penicillin binding
JMUB0001_RS06160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JMUB0001_RS06165	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JMUB0001_RS06175	COG4483	Protein conserved in bacteria
JMUB0001_RS06180	COG1940	carbohydrate kinase activity
JMUB0001_RS06185	COG0011	TIGRFAM Protein of
JMUB0001_RS06190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JMUB0001_RS06195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JMUB0001_RS06205	COG4537	Required for transformation and DNA binding
JMUB0001_RS06230	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JMUB0001_RS06235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JMUB0001_RS06250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JMUB0001_RS06255	COG0095	Lipoate-protein ligase
JMUB0001_RS06270	COG0006	proline dipeptidase activity
JMUB0001_RS06275	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JMUB0001_RS06280	COG0511	ligase activity, forming carbon-carbon bonds
JMUB0001_RS06285	COG0439	Biotin carboxylase
JMUB0001_RS06290	COG1302	Protein conserved in bacteria
JMUB0001_RS06295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JMUB0001_RS06300	COG1570	exodeoxyribonuclease VII activity
JMUB0001_RS06315	COG1438	arginine binding
JMUB0001_RS06320	COG0497	DNA recombination
JMUB0001_RS06325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMUB0001_RS06330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JMUB0001_RS06335	COG0022	dehydrogenase e1 component
JMUB0001_RS06340	COG0508	dehydrogenase complex catalyzes the overall conversion of
JMUB0001_RS06350	COG4129	membrane
JMUB0001_RS06355	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMUB0001_RS06360	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JMUB0001_RS06365	COG0366	Alpha amylase catalytic
JMUB0001_RS06375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JMUB0001_RS06380	COG1234	tRNA 3'-trailer cleavage
JMUB0001_RS06385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JMUB0001_RS06390	COG0300	oxidoreductase activity
JMUB0001_RS06400	COG0667	Aldo Keto reductase
JMUB0001_RS06405	COG0494	nUDIX hydrolase
JMUB0001_RS06410	COG0735	belongs to the Fur family
JMUB0001_RS06415	COG4974	Belongs to the 'phage' integrase family
JMUB0001_RS06425	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JMUB0001_RS06430	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JMUB0001_RS06435	COG1187	pseudouridine synthase activity
JMUB0001_RS06440	COG0745	RESPONSE REGULATOR receiver
JMUB0001_RS06455	COG1141	Ferredoxin
JMUB0001_RS06465	COG0514	ATP-dependent DNA helicase (RecQ)
JMUB0001_RS06470	COG1388	LysM domain
JMUB0001_RS06470	COG1388	LysM domain
JMUB0001_RS06475	COG0492	ferredoxin-NADP+ reductase activity
JMUB0001_RS06485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JMUB0001_RS06490	COG0539	negative regulation of cytoplasmic translation
JMUB0001_RS06495	COG1160	GTP binding
JMUB0001_RS06500	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JMUB0001_RS06515	COG2226	methyltransferase
JMUB0001_RS06520	COG0142	geranyltranstransferase activity
JMUB0001_RS06525	COG0105	UTP biosynthetic process
JMUB0001_RS06530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JMUB0001_RS06535	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JMUB0001_RS06540	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JMUB0001_RS06550	COG5582	Belongs to the UPF0302 family
JMUB0001_RS06555	COG4347	Protein of unknown function (DUF1405)
JMUB0001_RS06560	COG2738	Putative neutral zinc metallopeptidase
JMUB0001_RS06565	COG1694	Mazg nucleotide pyrophosphohydrolase
JMUB0001_RS06570	COG0438	transferase activity, transferring glycosyl groups
JMUB0001_RS06575	COG0617	tRNA 3'-terminal CCA addition
JMUB0001_RS06585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JMUB0001_RS06585	COG1199	ATP-dependent helicase activity
JMUB0001_RS06590	COG0017	Asparaginyl-tRNA synthetase
JMUB0001_RS06595	COG3935	DnaD domain protein
JMUB0001_RS06600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JMUB0001_RS06610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JMUB0001_RS06610	COG4499	WXG100 protein secretion system (Wss), protein YukC
JMUB0001_RS06615	COG3331	DNA recombination
JMUB0001_RS06625	COG4474	Belongs to the UPF0398 family
JMUB0001_RS06630	COG3599	regulation of cell shape
JMUB0001_RS06640	COG0116	Belongs to the methyltransferase superfamily
JMUB0001_RS06650	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JMUB0001_RS06655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JMUB0001_RS06665	COG0328	RNA-DNA hybrid ribonuclease activity
JMUB0001_RS06670	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JMUB0001_RS06680	COG1413	lyase activity
JMUB0001_RS06685	COG1413	lyase activity
JMUB0001_RS06715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JMUB0001_RS06720	COG2190	(PTS) system
JMUB0001_RS06725	COG4479	Belongs to the UPF0346 family
JMUB0001_RS06730	COG0793	Belongs to the peptidase S41A family
JMUB0001_RS06740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMUB0001_RS06745	COG0671	phosphoesterase, PA-phosphatase related
JMUB0001_RS06750	COG3842	ATPase activity
JMUB0001_RS06755	COG4209	transmembrane transport
JMUB0001_RS06765	COG0395	ABC-type sugar transport system, permease component
JMUB0001_RS06775	COG0534	Mate efflux family protein
JMUB0001_RS06780	COG1349	DNA-binding transcription factor activity
JMUB0001_RS06785	COG0745	RESPONSE REGULATOR receiver
JMUB0001_RS06790	COG5002	protein histidine kinase activity
JMUB0001_RS06800	COG0567	Dehydrogenase, E1 component
JMUB0001_RS06810	COG3177	Filamentation induced by cAMP protein fic
JMUB0001_RS06815	COG1131	(ABC) transporter
JMUB0001_RS06840	COG0714	Associated with various cellular activities
JMUB0001_RS06845	COG4548	von Willebrand factor, type A
JMUB0001_RS06850	COG1114	Component of the transport system for branched-chain amino acids
JMUB0001_RS06855	COG3853	Toxic anion resistance protein (TelA)
JMUB0001_RS06865	COG1254	Belongs to the acylphosphatase family
JMUB0001_RS06875	COG1278	Cold shock
JMUB0001_RS06905	COG1473	amidohydrolase
JMUB0001_RS06915	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JMUB0001_RS06920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JMUB0001_RS06925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JMUB0001_RS06930	COG0527	aspartate kinase activity
JMUB0001_RS06935	COG0488	(ABC) transporter
JMUB0001_RS06940	COG2996	Protein conserved in bacteria
JMUB0001_RS06945	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JMUB0001_RS06950	COG0573	inorganic phosphate transmembrane transporter activity
JMUB0001_RS06955	COG0581	inorganic phosphate transmembrane transporter activity
JMUB0001_RS06960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JMUB0001_RS06965	COG0704	Plays a role in the regulation of phosphate uptake
JMUB0001_RS06970	COG1164	Oligoendopeptidase f
JMUB0001_RS07005	COG2348	transferase activity, transferring amino-acyl groups
JMUB0001_RS07010	COG2348	transferase activity, transferring amino-acyl groups
JMUB0001_RS07020	COG0159	tryptophan synthase activity
JMUB0001_RS07025	COG0133	tryptophan synthase activity
JMUB0001_RS07030	COG0135	phosphoribosylanthranilate isomerase activity
JMUB0001_RS07035	COG0134	indole-3-glycerol-phosphate synthase activity
JMUB0001_RS07040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JMUB0001_RS07045	COG0512	Glutamine amidotransferase of anthranilate synthase
JMUB0001_RS07050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JMUB0001_RS07055	COG1363	Peptidase, m42
JMUB0001_RS07060	COG0287	Prephenate dehydrogenase
JMUB0001_RS07065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JMUB0001_RS07070	COG1942	4-Oxalocrotonate Tautomerase
JMUB0001_RS07085	COG0392	lysyltransferase activity
JMUB0001_RS07085	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JMUB0001_RS07090	COG0628	permease
JMUB0001_RS07095	COG3711	transcriptional antiterminator
JMUB0001_RS07100	COG1115	amino acid carrier protein
JMUB0001_RS07105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JMUB0001_RS07110	COG0187	DNA topoisomerase II activity
JMUB0001_RS07115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JMUB0001_RS07125	COG0824	Thioesterase
JMUB0001_RS07130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JMUB0001_RS07135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JMUB0001_RS07140	COG1970	mechanosensitive ion channel activity
JMUB0001_RS07145	COG0419	ATPase involved in DNA repair
JMUB0001_RS07150	COG0420	3'-5' exonuclease activity
JMUB0001_RS07155	COG4846	Membrane protein involved in cytochrome C biogenesis
JMUB0001_RS07180	COG0582	viral genome integration into host DNA
JMUB0001_RS07190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JMUB0001_RS07195	COG4224	UPF0291 protein
JMUB0001_RS07205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JMUB0001_RS07210	COG2340	Cysteine-rich secretory protein family
JMUB0001_RS07215	COG0516	GMP reductase activity
JMUB0001_RS07220	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JMUB0001_RS07230	COG0753	catalase activity
JMUB0001_RS07235	COG0833	amino acid
JMUB0001_RS07250	COG0083	homoserine kinase activity
JMUB0001_RS07255	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JMUB0001_RS07260	COG0460	homoserine dehydrogenase
JMUB0001_RS07265	COG0527	aspartate kinase activity
JMUB0001_RS07280	COG1525	nuclease
JMUB0001_RS07295	COG2197	response regulator
JMUB0001_RS07300	COG4585	Histidine kinase
JMUB0001_RS07315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JMUB0001_RS07365	COG0789	Transcriptional regulator
JMUB0001_RS07370	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JMUB0001_RS07375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JMUB0001_RS07380	COG0386	Belongs to the glutathione peroxidase family
JMUB0001_RS07385	COG1923	regulation of RNA biosynthetic process
JMUB0001_RS07390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JMUB0001_RS07400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JMUB0001_RS07405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JMUB0001_RS07410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JMUB0001_RS07420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JMUB0001_RS07425	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JMUB0001_RS07435	COG4550	Control of competence regulator ComK, YlbF/YmcA
JMUB0001_RS07440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JMUB0001_RS07450	COG4195	phage-related replication protein
JMUB0001_RS07455	COG1013	pyruvate-flavodoxin oxidoreductase activity
JMUB0001_RS07460	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JMUB0001_RS07460	COG0674	pyruvate-flavodoxin oxidoreductase activity
JMUB0001_RS07465	COG1692	metallophosphoesterase
JMUB0001_RS07475	COG1418	mRNA catabolic process
JMUB0001_RS07480	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JMUB0001_RS07485	COG1058	Belongs to the CinA family
JMUB0001_RS07485	COG1546	Belongs to the CinA family
JMUB0001_RS07490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JMUB0001_RS07505	COG0300	oxidoreductase activity
JMUB0001_RS07510	COG0612	Peptidase, M16
JMUB0001_RS07515	COG0612	Peptidase, M16
JMUB0001_RS07520	COG2188	Transcriptional regulator
JMUB0001_RS07525	COG1674	ftsk spoiiie
JMUB0001_RS07530	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JMUB0001_RS07535	COG1185	polyribonucleotide nucleotidyltransferase activity
JMUB0001_RS07540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JMUB0001_RS07545	COG0196	riboflavin kinase activity
JMUB0001_RS07550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JMUB0001_RS07555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JMUB0001_RS07560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JMUB0001_RS07565	COG1358	cellular component organization or biogenesis
JMUB0001_RS07570	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JMUB0001_RS07575	COG0195	Participates in both transcription termination and antitermination
JMUB0001_RS07580	COG0779	Required for maturation of 30S ribosomal subunits
JMUB0001_RS07585	COG2176	DNA-directed DNA polymerase activity
JMUB0001_RS07590	COG0442	prolyl-tRNA aminoacylation
JMUB0001_RS07600	COG4589	Belongs to the CDS family
JMUB0001_RS07605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JMUB0001_RS07610	COG0233	cytoplasmic translational termination
JMUB0001_RS07615	COG0528	UMP kinase activity
JMUB0001_RS07620	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JMUB0001_RS07625	COG0052	Belongs to the universal ribosomal protein uS2 family
JMUB0001_RS07640	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JMUB0001_RS07645	COG4974	Belongs to the 'phage' integrase family
JMUB0001_RS07650	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JMUB0001_RS07655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JMUB0001_RS07660	COG0758	DNA mediated transformation
JMUB0001_RS07665	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JMUB0001_RS07670	COG0045	succinate-CoA ligase (ADP-forming) activity
JMUB0001_RS07675	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JMUB0001_RS07685	COG4485	Bacterial membrane protein, YfhO
JMUB0001_RS07705	COG0335	large ribosomal subunit rRNA binding
JMUB0001_RS07710	COG0336	Belongs to the RNA methyltransferase TrmD family
JMUB0001_RS07715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JMUB0001_RS07720	COG0228	four-way junction DNA binding
JMUB0001_RS07725	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JMUB0001_RS07730	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JMUB0001_RS07735	COG0552	protein localization to endoplasmic reticulum
JMUB0001_RS07740	COG1196	nuclear chromosome segregation
JMUB0001_RS07745	COG0571	ribonuclease III activity
JMUB0001_RS07750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JMUB0001_RS07765	COG0416	fatty acid biosynthetic process
JMUB0001_RS07770	COG1349	DNA-binding transcription factor activity
JMUB0001_RS07775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JMUB0001_RS07790	COG1461	Dihydroxyacetone kinase
JMUB0001_RS07795	COG1302	Protein conserved in bacteria
JMUB0001_RS07800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JMUB0001_RS07805	COG1564	THIamine pyrophosphokinase
JMUB0001_RS07810	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JMUB0001_RS07815	COG1162	GTPase activity
JMUB0001_RS07820	COG2807	transmembrane transport
JMUB0001_RS07830	COG0631	protein serine/threonine phosphatase activity
JMUB0001_RS07835	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JMUB0001_RS07840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JMUB0001_RS07840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JMUB0001_RS07845	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JMUB0001_RS07850	COG0242	peptide deformylase activity
JMUB0001_RS07860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JMUB0001_RS07865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JMUB0001_RS07870	COG1758	RNA polymerase activity
JMUB0001_RS07875	COG0194	GDP metabolic process
JMUB0001_RS07880	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JMUB0001_RS07895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JMUB0001_RS07900	COG0284	orotidine-5'-phosphate decarboxylase activity
JMUB0001_RS07905	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JMUB0001_RS07910	COG0505	Belongs to the CarA family
JMUB0001_RS07915	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JMUB0001_RS07920	COG0540	Belongs to the ATCase OTCase family
JMUB0001_RS07925	COG2233	PERMEase
JMUB0001_RS07930	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JMUB0001_RS07935	COG0564	pseudouridine synthase activity
JMUB0001_RS07940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JMUB0001_RS07950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JMUB0001_RS07955	COG3599	regulation of cell shape
JMUB0001_RS07965	COG0762	integral membrane protein
JMUB0001_RS07970	COG1799	cell septum assembly
JMUB0001_RS07975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JMUB0001_RS07980	COG1496	oxidoreductase activity
JMUB0001_RS07985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JMUB0001_RS07990	COG0849	cell division
JMUB0001_RS07995	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JMUB0001_RS08000	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JMUB0001_RS08005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JMUB0001_RS08010	COG0768	penicillin binding
JMUB0001_RS08015	COG4839	cell division protein FtsL
JMUB0001_RS08020	COG0275	rRNA processing
JMUB0001_RS08030	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JMUB0001_RS08035	COG0454	-acetyltransferase
JMUB0001_RS08040	COG1011	Hydrolase
JMUB0001_RS08075	COG0860	N-Acetylmuramoyl-L-alanine amidase
JMUB0001_RS08075	COG1388	LysM domain
JMUB0001_RS08110	COG5434	Belongs to the glycosyl hydrolase 28 family
JMUB0001_RS08130	COG3953	SLT domain
JMUB0001_RS08130	COG5280	Phage tail tape measure protein TP901
JMUB0001_RS08220	COG0756	dUTP diphosphatase activity
JMUB0001_RS08285	COG1484	DNA-dependent DNA replication
JMUB0001_RS08355	COG3561	AntA/AntB antirepressor
JMUB0001_RS08365	COG1396	sequence-specific DNA binding
JMUB0001_RS08385	COG0582	viral genome integration into host DNA
JMUB0001_RS08395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JMUB0001_RS08400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JMUB0001_RS08405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JMUB0001_RS08410	COG1053	succinate dehydrogenase
JMUB0001_RS08415	COG2009	succinate dehydrogenase
JMUB0001_RS08420	COG0322	excinuclease ABC activity
JMUB0001_RS08425	COG3118	belongs to the thioredoxin family
JMUB0001_RS08430	COG1193	negative regulation of DNA recombination
JMUB0001_RS08435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JMUB0001_RS08435	COG1796	DNA polymerase
JMUB0001_RS08445	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JMUB0001_RS08450	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JMUB0001_RS08455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMUB0001_RS08455	COG0072	phenylalanine-tRNA ligase activity
JMUB0001_RS08460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JMUB0001_RS08465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JMUB0001_RS08475	COG4509	Sortase family
JMUB0001_RS08520	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JMUB0001_RS08540	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JMUB0001_RS08545	COG0742	ribosomal rna small subunit methyltransferase
JMUB0001_RS08555	COG4471	UPF0298 protein
JMUB0001_RS08560	COG0584	glycerophosphoryl diester phosphodiesterase
JMUB0001_RS08565	COG3679	Belongs to the UPF0342 family
JMUB0001_RS08580	COG0109	protoheme IX farnesyltransferase activity
JMUB0001_RS08585	COG1612	heme a metabolic process
JMUB0001_RS08595	COG0772	Belongs to the SEDS family
JMUB0001_RS08600	COG4838	Belongs to the UPF0358 family
JMUB0001_RS08605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JMUB0001_RS08610	COG4896	Protein conserved in bacteria
JMUB0001_RS08615	COG1217	gtp-binding protein TYPA
JMUB0001_RS08625	COG0483	inositol monophosphate 1-phosphatase activity
JMUB0001_RS08630	COG4493	Belongs to the UPF0637 family
JMUB0001_RS08635	COG1914	H( )-stimulated, divalent metal cation uptake system
JMUB0001_RS08660	COG1176	ABC-type spermidine putrescine transport system, permease component I
JMUB0001_RS08675	COG4476	Belongs to the UPF0223 family
JMUB0001_RS08685	COG0508	dehydrogenase complex catalyzes the overall conversion of
JMUB0001_RS08690	COG0022	dehydrogenase e1 component
JMUB0001_RS08695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JMUB0001_RS08705	COG0242	peptide deformylase activity
JMUB0001_RS08710	COG5503	Protein of unknown function (DUF1447)
JMUB0001_RS08715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JMUB0001_RS08725	COG0569	domain protein
JMUB0001_RS08730	COG1294	oxidase, subunit
JMUB0001_RS08735	COG1271	oxidase subunit
JMUB0001_RS08750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMUB0001_RS08760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JMUB0001_RS08780	COG4172	Belongs to the ABC transporter superfamily
JMUB0001_RS08785	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JMUB0001_RS08790	COG0151	Belongs to the GarS family
JMUB0001_RS08795	COG0138	bifunctional purine biosynthesis protein purh
JMUB0001_RS08800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JMUB0001_RS08805	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JMUB0001_RS08810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JMUB0001_RS08815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JMUB0001_RS08820	COG0047	phosphoribosylformylglycinamidine synthase activity
JMUB0001_RS08825	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JMUB0001_RS08830	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JMUB0001_RS08835	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JMUB0001_RS08840	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JMUB0001_RS08845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JMUB0001_RS08850	COG1017	nitric oxide dioxygenase activity
JMUB0001_RS08850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JMUB0001_RS08860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JMUB0001_RS08865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JMUB0001_RS08875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JMUB0001_RS08890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JMUB0001_RS08895	COG1316	TRANSCRIPTIONal
JMUB0001_RS08920	COG3594	Acyltransferase
JMUB0001_RS08925	COG0436	Aminotransferase
JMUB0001_RS08930	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JMUB0001_RS08940	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JMUB0001_RS08945	COG1169	isochorismate synthase
JMUB0001_RS08950	COG1575	Belongs to the MenA family. Type 1 subfamily
JMUB0001_RS09025	COG4873	Protein conserved in bacteria
JMUB0001_RS09035	COG0737	Belongs to the 5'-nucleotidase family
JMUB0001_RS09040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JMUB0001_RS09045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JMUB0001_RS09050	COG0861	Integral membrane protein TerC family
JMUB0001_RS09055	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JMUB0001_RS09065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JMUB0001_RS09070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JMUB0001_RS09075	COG2814	Major facilitator Superfamily
JMUB0001_RS09080	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JMUB0001_RS09085	COG2382	esterase
JMUB0001_RS09090	COG0628	permease
JMUB0001_RS09100	COG0569	domain protein
JMUB0001_RS09100	COG0475	glutathione-regulated potassium exporter activity
JMUB0001_RS09105	COG2239	Acts as a magnesium transporter
JMUB0001_RS09110	COG0564	pseudouridine synthase activity
JMUB0001_RS09115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JMUB0001_RS09120	COG2357	RelA SpoT domain protein
JMUB0001_RS09130	COG4116	CYTH
JMUB0001_RS09135	COG2346	COG2346, Truncated hemoglobins
JMUB0001_RS09140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JMUB0001_RS09145	COG1164	Oligoendopeptidase f
JMUB0001_RS09155	COG4862	establishment of competence for transformation
JMUB0001_RS09160	COG1393	Belongs to the ArsC family
JMUB0001_RS09165	COG0180	Tryptophanyl-tRNA synthetase
JMUB0001_RS09170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JMUB0001_RS09175	COG0601	transmembrane transport
JMUB0001_RS09180	COG4608	Belongs to the ABC transporter superfamily
JMUB0001_RS09185	COG0444	Belongs to the ABC transporter superfamily
JMUB0001_RS09190	COG0747	negative chemotaxis
JMUB0001_RS09200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JMUB0001_RS09210	COG1881	PFAM PEBP family protein
JMUB0001_RS09215	COG0542	response to heat
JMUB0001_RS09230	COG0561	phosphatase activity
JMUB0001_RS09235	COG0446	pyridine nucleotide-disulphide oxidoreductase
JMUB0001_RS09245	COG0179	Fumarylacetoacetate (FAA) hydrolase
JMUB0001_RS09250	COG1074	ATP-dependent DNA helicase activity
JMUB0001_RS09255	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JMUB0001_RS09270	COG0398	Pfam SNARE associated Golgi protein
JMUB0001_RS09275	COG0166	Belongs to the GPI family
JMUB0001_RS09280	COG0137	argininosuccinate synthase activity
JMUB0001_RS09285	COG0165	Argininosuccinate lyase
JMUB0001_RS09290	COG0584	glycerophosphoryl diester phosphodiesterase
JMUB0001_RS09305	COG1902	pentaerythritol trinitrate reductase activity
JMUB0001_RS09310	COG1098	S1 RNA binding domain
JMUB0001_RS09315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JMUB0001_RS09325	COG2111	Na H antiporter
JMUB0001_RS09325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JMUB0001_RS09330	COG2111	Na H antiporter
JMUB0001_RS09335	COG1006	Multisubunit Na H antiporter MnhC subunit
JMUB0001_RS09340	COG0651	ATP synthesis coupled electron transport
JMUB0001_RS09345	COG1863	multisubunit Na H antiporter MnhE subunit
JMUB0001_RS09350	COG2212	antiporter activity
JMUB0001_RS09355	COG1320	monovalent cation:proton antiporter activity
JMUB0001_RS09365	COG2050	protein possibly involved in aromatic compounds catabolism
JMUB0001_RS09370	COG2056	Na+-H+ antiporter family
JMUB0001_RS09375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JMUB0001_RS09380	COG1252	NADH dehydrogenase
JMUB0001_RS09385	COG0316	Belongs to the HesB IscA family
JMUB0001_RS09390	COG4844	belongs to the
JMUB0001_RS09395	COG1252	NADH dehydrogenase
JMUB0001_RS09400	COG4837	Protein of unknown function (DUF1462)
JMUB0001_RS09405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JMUB0001_RS09410	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JMUB0001_RS09420	COG1696	Membrane protein involved in D-alanine export
JMUB0001_RS09425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JMUB0001_RS09435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JMUB0001_RS09440	COG0647	UMP catabolic process
JMUB0001_RS09445	COG2445	Protein of unknown function DUF86
JMUB0001_RS09455	COG4470	Protein conserved in bacteria
JMUB0001_RS09460	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JMUB0001_RS09465	COG0737	Belongs to the 5'-nucleotidase family
JMUB0001_RS09470	COG0730	response to heat
JMUB0001_RS09475	COG1801	Protein of unknown function DUF72
JMUB0001_RS09480	COG2070	2-Nitropropane dioxygenase
JMUB0001_RS09485	COG1253	flavin adenine dinucleotide binding
JMUB0001_RS09490	COG0719	Fe-S assembly protein
JMUB0001_RS09495	COG0822	iron-sulfur transferase activity
JMUB0001_RS09500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JMUB0001_RS09505	COG0719	Fe-S assembly protein
JMUB0001_RS09510	COG0396	ATPase activity
JMUB0001_RS09530	COG1464	Belongs to the NlpA lipoprotein family
JMUB0001_RS09535	COG2011	ABC-type metal ion transport system permease component
JMUB0001_RS09540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JMUB0001_RS09550	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JMUB0001_RS09555	COG0509	glycine decarboxylation via glycine cleavage system
JMUB0001_RS09560	COG1393	Belongs to the ArsC family
JMUB0001_RS09565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JMUB0001_RS09575	COG0710	3-dehydroquinate dehydratase activity
JMUB0001_RS09580	COG1764	response to oxidative stress
JMUB0001_RS09590	COG1279	arginine transmembrane transporter activity
JMUB0001_RS09595	COG0406	alpha-ribazole phosphatase activity
JMUB0001_RS09650	COG1674	ftsk spoiiie
JMUB0001_RS09660	COG2946	Replication initiation factor
JMUB0001_RS09690	COG0791	NLP P60 protein
JMUB0001_RS09690	COG0741	lytic transglycosylase activity
JMUB0001_RS09745	COG4195	phage-related replication protein
JMUB0001_RS09765	COG1278	Cold shock
JMUB0001_RS09780	COG0519	Catalyzes the synthesis of GMP from XMP
JMUB0001_RS09790	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JMUB0001_RS09795	COG0557	exoribonuclease II activity
JMUB0001_RS09800	COG1647	Serine aminopeptidase, S33
JMUB0001_RS09805	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JMUB0001_RS09815	COG0148	phosphopyruvate hydratase activity
JMUB0001_RS09820	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JMUB0001_RS09825	COG0149	triose-phosphate isomerase activity
JMUB0001_RS09830	COG0126	phosphoglycerate kinase activity
JMUB0001_RS09835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JMUB0001_RS09840	COG2390	Transcriptional regulator
JMUB0001_RS09855	COG1090	epimerase
JMUB0001_RS09875	COG1481	regulation of sporulation
JMUB0001_RS09880	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JMUB0001_RS09885	COG1660	Displays ATPase and GTPase activities
JMUB0001_RS09890	COG0492	ferredoxin-NADP+ reductase activity
JMUB0001_RS09905	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JMUB0001_RS09910	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JMUB0001_RS09915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JMUB0001_RS09920	COG0556	nucleotide-excision repair
JMUB0001_RS09935	COG3942	CHAP domain
JMUB0001_RS09935	COG1388	LysM domain
JMUB0001_RS09945	COG0653	protein targeting
JMUB0001_RS09955	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JMUB0001_RS09960	COG1040	competence protein
JMUB0001_RS09965	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JMUB0001_RS09975	COG1739	Uncharacterized protein family UPF0029
JMUB0001_RS09980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JMUB0001_RS10000	COG2195	Cleaves the N-terminal amino acid of tripeptides
JMUB0001_RS10005	COG1929	Belongs to the glycerate kinase type-1 family
JMUB0001_RS10025	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JMUB0001_RS10035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JMUB0001_RS10040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JMUB0001_RS10045	COG1780	Probably involved in ribonucleotide reductase function
JMUB0001_RS10060	COG3104	oligopeptide transport
JMUB0001_RS10065	COG1597	lipid kinase activity
JMUB0001_RS10075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JMUB0001_RS10080	COG1174	glycine betaine transport
JMUB0001_RS10090	COG0514	ATP-dependent DNA helicase (RecQ)
JMUB0001_RS10095	COG0488	(ABC) transporter
JMUB0001_RS10105	COG1368	sulfuric ester hydrolase activity
JMUB0001_RS10115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JMUB0001_RS10130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JMUB0001_RS10140	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JMUB0001_RS10145	COG0720	synthase
JMUB0001_RS10150	COG0602	queuosine metabolic process
JMUB0001_RS10170	COG0745	RESPONSE REGULATOR receiver
JMUB0001_RS10175	COG5002	protein histidine kinase activity
JMUB0001_RS10180	COG0463	Glycosyl transferase, family 2
JMUB0001_RS10185	COG0656	L-ascorbic acid biosynthetic process
JMUB0001_RS10190	COG1253	flavin adenine dinucleotide binding
JMUB0001_RS10195	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JMUB0001_RS10200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMUB0001_RS10200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JMUB0001_RS10200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JMUB0001_RS10205	COG1105	Belongs to the carbohydrate kinase PfkB family
JMUB0001_RS10210	COG1349	DNA-binding transcription factor activity
JMUB0001_RS10215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JMUB0001_RS10240	COG0415	Belongs to the DNA photolyase family
JMUB0001_RS10245	COG0471	metal ion transport
JMUB0001_RS10250	COG0039	L-malate dehydrogenase activity
JMUB0001_RS10270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JMUB0001_RS10275	COG4988	ABC transporter
JMUB0001_RS10280	COG1968	undecaprenyl-diphosphatase activity
JMUB0001_RS10290	COG1671	Belongs to the UPF0178 family
JMUB0001_RS10295	COG1611	Belongs to the LOG family
JMUB0001_RS10305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JMUB0001_RS10330	COG2839	Protein conserved in bacteria
JMUB0001_RS10340	COG0583	DNA-binding transcription factor activity
JMUB0001_RS10355	COG0217	transcriptional regulatory protein
JMUB0001_RS10365	COG1917	Cupin 2, conserved barrel domain protein
JMUB0001_RS10365	COG4977	sequence-specific DNA binding
JMUB0001_RS10375	COG3942	CHAP domain
JMUB0001_RS10375	COG1388	LysM domain
JMUB0001_RS10380	COG0306	phosphate transporter
JMUB0001_RS10385	COG1392	Phosphate transport regulator
JMUB0001_RS10390	COG0577	efflux transmembrane transporter activity
JMUB0001_RS10395	COG1136	(ABC) transporter
JMUB0001_RS10400	COG2205	protein histidine kinase activity
JMUB0001_RS10405	COG0745	RESPONSE REGULATOR receiver
JMUB0001_RS10410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JMUB0001_RS10420	COG0657	acetylesterase activity
JMUB0001_RS10425	COG3949	Membrane
JMUB0001_RS10435	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JMUB0001_RS10445	COG2376	Dihydroxyacetone kinase
JMUB0001_RS10450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMUB0001_RS10455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMUB0001_RS10460	COG1120	ATPase activity
JMUB0001_RS10465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JMUB0001_RS10470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JMUB0001_RS10475	COG1132	(ABC) transporter
JMUB0001_RS10480	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JMUB0001_RS10490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JMUB0001_RS10495	COG1682	transport, permease protein
JMUB0001_RS10500	COG1134	teichoic acid transport
JMUB0001_RS10505	COG5609	conserved protein (DUF2294)
JMUB0001_RS10515	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JMUB0001_RS10525	COG1321	iron dependent repressor
JMUB0001_RS10530	COG1121	(ABC) transporter
JMUB0001_RS10535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JMUB0001_RS10540	COG0803	Belongs to the bacterial solute-binding protein 9 family
JMUB0001_RS10550	COG1320	monovalent cation:proton antiporter activity
JMUB0001_RS10555	COG2212	antiporter activity
JMUB0001_RS10560	COG1863	multisubunit Na H antiporter MnhE subunit
JMUB0001_RS10565	COG0651	ATP synthesis coupled electron transport
JMUB0001_RS10570	COG1006	Multisubunit Na H antiporter MnhC subunit
JMUB0001_RS10575	COG2111	Na H antiporter
JMUB0001_RS10580	COG2111	Na H antiporter
JMUB0001_RS10580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JMUB0001_RS10615	COG0596	Alpha beta hydrolase
JMUB0001_RS10640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JMUB0001_RS10645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JMUB0001_RS10660	COG0789	Transcriptional regulator
JMUB0001_RS10665	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JMUB0001_RS10670	COG0018	arginyl-trna synthetase
JMUB0001_RS10690	COG3875	lactate racemase activity
JMUB0001_RS10695	COG1606	tRNA processing
JMUB0001_RS10700	COG1691	(AIR) carboxylase
JMUB0001_RS10705	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JMUB0001_RS10720	COG1078	dGTPase activity
JMUB0001_RS10730	COG0655	NAD(P)H dehydrogenase (quinone) activity
JMUB0001_RS10735	COG0667	Aldo Keto reductase
JMUB0001_RS10745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JMUB0001_RS10750	COG4844	belongs to the
JMUB0001_RS10770	COG0095	Lipoate-protein ligase
JMUB0001_RS10775	COG0280	phosphate acetyltransferase
JMUB0001_RS10780	COG3253	May function as heme-dependent peroxidase
JMUB0001_RS10800	COG2363	Small membrane protein
JMUB0001_RS10810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JMUB0001_RS10815	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JMUB0001_RS10820	COG0351	phosphomethylpyrimidine kinase
JMUB0001_RS10835	COG0477	Major facilitator Superfamily
JMUB0001_RS10850	COG0183	Belongs to the thiolase family
JMUB0001_RS10855	COG0318	PFAM AMP-dependent synthetase and ligase
JMUB0001_RS10870	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JMUB0001_RS10875	COG0363	glucosamine-6-phosphate deaminase activity
JMUB0001_RS10880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JMUB0001_RS10885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JMUB0001_RS10895	COG2271	Major facilitator Superfamily
JMUB0001_RS10900	COG0438	transferase activity, transferring glycosyl groups
JMUB0001_RS10905	COG0431	NADPH-dependent FMN reductase
JMUB0001_RS10910	COG0561	phosphatase activity
JMUB0001_RS10920	COG1428	Deoxynucleoside kinase
JMUB0001_RS10925	COG1428	Deoxynucleoside kinase
JMUB0001_RS10935	COG0546	phosphoglycolate phosphatase activity
JMUB0001_RS10940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JMUB0001_RS10950	COG0737	Belongs to the 5'-nucleotidase family
JMUB0001_RS10980	COG1473	amidohydrolase
JMUB0001_RS10985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JMUB0001_RS10990	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JMUB0001_RS11000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JMUB0001_RS11010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JMUB0001_RS11015	COG0085	RNA polymerase activity
JMUB0001_RS11020	COG2813	Specifically methylates the guanine in position
JMUB0001_RS11025	COG0222	ribosome binding
JMUB0001_RS11030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JMUB0001_RS11040	COG0081	regulation of translation
JMUB0001_RS11045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JMUB0001_RS11050	COG0250	Participates in transcription elongation, termination and antitermination
JMUB0001_RS11055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JMUB0001_RS11060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JMUB0001_RS11070	COG3688	RNA-binding protein containing a PIN domain
JMUB0001_RS11080	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JMUB0001_RS11085	COG0215	cysteine-tRNA ligase activity
JMUB0001_RS11090	COG1045	serine acetyltransferase
JMUB0001_RS11095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JMUB0001_RS11100	COG4956	integral membrane protein (PIN domain superfamily)
JMUB0001_RS11105	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JMUB0001_RS11110	COG0542	response to heat
JMUB0001_RS11115	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JMUB0001_RS11120	COG3880	PFAM UvrB UvrC protein
JMUB0001_RS11125	COG4463	regulation of RNA biosynthetic process
JMUB0001_RS11130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JMUB0001_RS11135	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JMUB0001_RS11140	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JMUB0001_RS11145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JMUB0001_RS11210	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JMUB0001_RS11215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JMUB0001_RS11220	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JMUB0001_RS11230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JMUB0001_RS11235	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JMUB0001_RS11240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JMUB0001_RS11245	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JMUB0001_RS11250	COG0037	tRNA processing
JMUB0001_RS11255	COG1098	S1 RNA binding domain
JMUB0001_RS11265	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JMUB0001_RS11270	COG3956	TIGRFAM MazG family protein
JMUB0001_RS11275	COG2244	polysaccharide biosynthetic process
JMUB0001_RS11280	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JMUB0001_RS11290	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JMUB0001_RS11295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JMUB0001_RS11300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JMUB0001_RS11305	COG2088	sporulation resulting in formation of a cellular spore
JMUB0001_RS11310	COG0251	oxidation-reduction process
JMUB0001_RS11315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMUB0001_RS11320	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JMUB0001_RS11325	COG4466	Protein conserved in bacteria
JMUB0001_RS11330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JMUB0001_RS11335	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JMUB0001_RS11340	COG0084	hydrolase, TatD family'
JMUB0001_RS11345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMUB0001_RS11345	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JMUB0001_RS11350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JMUB0001_RS11355	COG2827	Endonuclease containing a URI domain
JMUB0001_RS11360	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JMUB0001_RS11365	COG4467	Involved in initiation control of chromosome replication
JMUB0001_RS11370	COG1774	PSP1 C-terminal conserved region
JMUB0001_RS11375	COG0470	DNA polymerase III
JMUB0001_RS11380	COG3870	Protein conserved in bacteria
JMUB0001_RS11385	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JMUB0001_RS11390	COG1982	Orn Lys Arg decarboxylase major
JMUB0001_RS11415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JMUB0001_RS11420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JMUB0001_RS11425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JMUB0001_RS11445	COG0493	'glutamate synthase
JMUB0001_RS11450	COG0067	glutamate synthase
JMUB0001_RS11450	COG0070	glutamate synthase
JMUB0001_RS11450	COG0069	glutamate synthase activity
JMUB0001_RS11455	COG0583	DNA-binding transcription factor activity
JMUB0001_RS11485	COG0438	transferase activity, transferring glycosyl groups
JMUB0001_RS11490	COG1388	LysM domain
JMUB0001_RS11490	COG3942	CHAP domain
JMUB0001_RS11500	COG2011	ABC-type metal ion transport system permease component
JMUB0001_RS11505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JMUB0001_RS11515	COG0626	cystathionine gamma-synthase activity
JMUB0001_RS11520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JMUB0001_RS11535	COG0733	neurotransmitter:sodium symporter activity
JMUB0001_RS11545	COG1647	Serine aminopeptidase, S33
JMUB0001_RS11570	COG5609	conserved protein (DUF2294)
JMUB0001_RS11575	COG3002	Belongs to the UPF0753 family
JMUB0001_RS11580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JMUB0001_RS11600	COG0523	cobalamin synthesis protein
JMUB0001_RS11610	COG2211	Major facilitator Superfamily
JMUB0001_RS11620	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JMUB0001_RS11640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JMUB0001_RS11750	COG0582	viral genome integration into host DNA
JMUB0001_RS11755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JMUB0001_RS11755	COG0519	Catalyzes the synthesis of GMP from XMP
JMUB0001_RS11760	COG0516	GMP reductase activity
JMUB0001_RS11760	COG0517	IMP dehydrogenase activity
JMUB0001_RS11765	COG2233	PERMEase
JMUB0001_RS11770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JMUB0001_RS11785	COG5183	chlorophyll binding
JMUB0001_RS11790	COG1823	symporter activity
JMUB0001_RS11795	COG0778	Nitroreductase
JMUB0001_RS11805	COG0450	alkyl hydroperoxide reductase
JMUB0001_RS11810	COG3634	alkyl hydroperoxide reductase activity
JMUB0001_RS11830	COG1280	lysine exporter protein (LysE YggA)
JMUB0001_RS11875	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JMUB0001_RS11885	COG0360	Binds together with S18 to 16S ribosomal RNA
JMUB0001_RS11895	COG1011	Hydrolase
JMUB0001_RS11920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JMUB0001_RS11940	COG0012	GTP binding
JMUB0001_RS11945	COG4481	Protein conserved in bacteria
JMUB0001_RS11950	COG0668	transmembrane transport
JMUB0001_RS11955	COG1475	DNA binding
JMUB0001_RS11965	COG0626	cystathionine gamma-synthase activity
JMUB0001_RS11970	COG0626	cystathionine gamma-synthase activity
JMUB0001_RS11975	COG0646	methionine synthase
JMUB0001_RS11975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JMUB0001_RS11980	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JMUB0001_RS11990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JMUB0001_RS11995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JMUB0001_RS12000	COG0183	Belongs to the thiolase family
JMUB0001_RS12005	COG0346	lactoylglutathione lyase activity
JMUB0001_RS12020	COG1476	TRANSCRIPTIONal
JMUB0001_RS12030	COG1131	(ABC) transporter
JMUB0001_RS12040	COG2814	Major facilitator Superfamily
JMUB0001_RS12075	COG1136	(ABC) transporter
JMUB0001_RS12080	COG0577	efflux transmembrane transporter activity
JMUB0001_RS12110	COG0577	efflux transmembrane transporter activity
JMUB0001_RS12115	COG1136	(ABC) transporter
JMUB0001_RS12120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JMUB0001_RS12160	COG0300	oxidoreductase activity
JMUB0001_RS12165	COG1475	DNA binding
JMUB0001_RS12170	COG0357	Ribosomal RNA small subunit methyltransferase G
JMUB0001_RS12175	COG0445	tRNA wobble uridine modification
JMUB0001_RS12180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JMUB0001_RS12185	COG0594	ribonuclease P activity