locus-tag	class	description
NF392_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NF392_RS00010	COG0592	DNA-directed DNA polymerase activity
NF392_RS00015	COG2501	S4 domain
NF392_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NF392_RS00025	COG0187	DNA topoisomerase II activity
NF392_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NF392_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NF392_RS00045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NF392_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NF392_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NF392_RS00075	COG0359	binds to the 23S rRNA
NF392_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
NF392_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NF392_RS00100	COG0745	RESPONSE REGULATOR receiver
NF392_RS00105	COG5002	protein histidine kinase activity
NF392_RS00110	COG4863	YycH protein
NF392_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NF392_RS00125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NF392_RS00130	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NF392_RS00240	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NF392_RS00250	COG0732	type I restriction modification DNA specificity domain
NF392_RS00255	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NF392_RS00265	COG1401	restriction endodeoxyribonuclease activity
NF392_RS00280	COG1401	restriction endodeoxyribonuclease activity
NF392_RS00285	COG4268	DNA restriction-modification system
NF392_RS00315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NF392_RS00320	COG1755	Isoprenylcysteine carboxyl methyltransferase
NF392_RS00325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NF392_RS00335	COG1136	(ABC) transporter
NF392_RS00345	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NF392_RS00350	COG1063	alcohol dehydrogenase
NF392_RS00355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NF392_RS00360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NF392_RS00395	COG0745	RESPONSE REGULATOR receiver
NF392_RS00400	COG2205	protein histidine kinase activity
NF392_RS00405	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NF392_RS00410	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NF392_RS00440	COG0601	transmembrane transport
NF392_RS00450	COG0444	Belongs to the ABC transporter superfamily
NF392_RS00475	COG3246	L-lysine catabolic process to acetate
NF392_RS00480	COG1250	3-hydroxyacyl-CoA dehydrogenase
NF392_RS00505	COG1174	glycine betaine transport
NF392_RS00520	COG1114	Component of the transport system for branched-chain amino acids
NF392_RS00525	COG1288	antiporter activity
NF392_RS00530	COG0549	Belongs to the carbamate kinase family
NF392_RS00545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF392_RS00550	COG2814	Major facilitator Superfamily
NF392_RS00555	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NF392_RS00580	COG2814	Major facilitator Superfamily
NF392_RS00590	COG1028	Short-chain dehydrogenase reductase Sdr
NF392_RS00615	COG2814	Major facilitator Superfamily
NF392_RS00635	COG2318	DinB family
NF392_RS00640	COG2311	Membrane
NF392_RS00645	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NF392_RS00650	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NF392_RS00660	COG0471	metal ion transport
NF392_RS00665	COG1733	regulation of RNA biosynthetic process
NF392_RS00670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF392_RS00700	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NF392_RS00705	COG1054	Belongs to the UPF0176 family
NF392_RS00710	COG3386	PFAM SMP-30 Gluconolaconase
NF392_RS00715	COG2353	YceI-like domain
NF392_RS00725	COG0579	oxidoreductase
NF392_RS00745	COG1686	Belongs to the peptidase S11 family
NF392_RS00780	COG0726	polysaccharide deacetylase
NF392_RS00815	COG2814	Major facilitator Superfamily
NF392_RS00825	COG0737	Belongs to the 5'-nucleotidase family
NF392_RS00840	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NF392_RS00845	COG3639	organic phosphonate transmembrane transporter activity
NF392_RS00855	COG0702	epimerase
NF392_RS00870	COG0201	protein transport
NF392_RS00880	COG1073	alpha beta
NF392_RS00890	COG0653	protein targeting
NF392_RS00900	COG0438	transferase activity, transferring glycosyl groups
NF392_RS00935	COG2814	Major facilitator Superfamily
NF392_RS00940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NF392_RS00945	COG0604	alcohol dehydrogenase
NF392_RS00960	COG2113	Glycine betaine
NF392_RS00965	COG2409	Drug exporters of the RND superfamily
NF392_RS00980	COG0583	DNA-binding transcription factor activity
NF392_RS00985	COG3842	ATPase activity
NF392_RS00990	COG1840	ABC-type Fe3 transport system, periplasmic component
NF392_RS01000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NF392_RS01005	COG1764	response to oxidative stress
NF392_RS01020	COG3942	CHAP domain
NF392_RS01020	COG1705	Flagellar rod assembly protein muramidase FlgJ
NF392_RS01020	COG1705	Flagellar rod assembly protein muramidase FlgJ
NF392_RS01020	COG3942	CHAP domain
NF392_RS01030	COG1482	cell wall glycoprotein biosynthetic process
NF392_RS01035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF392_RS01035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF392_RS01035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF392_RS01040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF392_RS01040	COG3711	transcriptional antiterminator
NF392_RS01045	COG2814	Major facilitator Superfamily
NF392_RS01050	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NF392_RS01125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF392_RS01155	COG2235	arginine
NF392_RS01160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NF392_RS01175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NF392_RS01190	COG2843	Capsule synthesis protein
NF392_RS01210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NF392_RS01215	COG3961	Belongs to the TPP enzyme family
NF392_RS01220	COG1846	Transcriptional regulator
NF392_RS01225	COG4195	phage-related replication protein
NF392_RS01230	COG4195	phage-related replication protein
NF392_RS01245	COG0702	epimerase
NF392_RS01250	COG1785	Belongs to the alkaline phosphatase family
NF392_RS01260	COG0745	RESPONSE REGULATOR receiver
NF392_RS01265	COG2205	protein histidine kinase activity
NF392_RS01270	COG1136	(ABC) transporter
NF392_RS01285	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF392_RS01310	COG0386	Belongs to the glutathione peroxidase family
NF392_RS01315	COG0175	sulfate reduction
NF392_RS01320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NF392_RS01325	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NF392_RS01340	COG0730	response to heat
NF392_RS01345	COG2046	Belongs to the sulfate adenylyltransferase family
NF392_RS01350	COG0529	Catalyzes the synthesis of activated sulfate
NF392_RS01355	COG2851	Citrate transporter
NF392_RS01370	COG1328	CTP reductase activity
NF392_RS01375	COG0602	queuosine metabolic process
NF392_RS01380	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NF392_RS01390	COG1510	regulation of RNA biosynthetic process
NF392_RS01395	COG1012	belongs to the aldehyde dehydrogenase family
NF392_RS01400	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NF392_RS01405	COG1473	amidohydrolase
NF392_RS01430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NF392_RS01435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NF392_RS01435	COG0574	Belongs to the PEP-utilizing enzyme family
NF392_RS01440	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NF392_RS01445	COG0579	oxidoreductase
NF392_RS01465	COG3588	fructose-bisphosphate aldolase
NF392_RS01470	COG0446	pyridine nucleotide-disulphide oxidoreductase
NF392_RS01495	COG0531	amino acid
NF392_RS01505	COG0583	DNA-binding transcription factor activity
NF392_RS01510	COG0039	L-malate dehydrogenase activity
NF392_RS01515	COG0028	Belongs to the TPP enzyme family
NF392_RS01520	COG3527	Alpha-acetolactate decarboxylase
NF392_RS01530	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NF392_RS01535	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NF392_RS01550	COG4640	response to antibiotic
NF392_RS01575	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NF392_RS01585	COG0167	dihydroorotate dehydrogenase activity
NF392_RS01590	COG3001	Fructosamine kinase
NF392_RS01605	COG0596	Alpha beta hydrolase
NF392_RS01615	COG1028	Short-chain dehydrogenase reductase Sdr
NF392_RS01640	COG1113	amino acid transport
NF392_RS01660	COG0741	lytic transglycosylase activity
NF392_RS01690	COG0436	Aminotransferase
NF392_RS01705	COG2608	mercury ion transmembrane transporter activity
NF392_RS01710	COG2217	Heavy metal translocating P-type atpase
NF392_RS01720	COG1028	Short-chain dehydrogenase reductase Sdr
NF392_RS01730	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NF392_RS01735	COG1012	belongs to the aldehyde dehydrogenase family
NF392_RS01770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NF392_RS01775	COG3425	synthase
NF392_RS01795	COG0583	DNA-binding transcription factor activity
NF392_RS01800	COG1380	Effector of murein hydrolase LrgA
NF392_RS01805	COG1346	cytolysis
NF392_RS01810	COG0028	Belongs to the TPP enzyme family
NF392_RS01820	COG1266	CAAX protease self-immunity
NF392_RS01835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF392_RS01840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF392_RS01850	COG0697	spore germination
NF392_RS01855	COG2207	Transcriptional regulator
NF392_RS01855	COG1917	Cupin 2, conserved barrel domain protein
NF392_RS01865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NF392_RS01875	COG2843	Capsule synthesis protein
NF392_RS01890	COG4975	Glucose uptake
NF392_RS01895	COG1869	D-ribose catabolic process
NF392_RS01905	COG1070	Carbohydrate kinase
NF392_RS01920	COG1760	l-serine dehydratase
NF392_RS01925	COG1760	l-serine dehydratase
NF392_RS01935	COG1247	-acetyltransferase
NF392_RS01940	COG3764	Sortase (surface protein transpeptidase)
NF392_RS01945	COG0561	phosphatase activity
NF392_RS01955	COG0778	Nitroreductase
NF392_RS01960	COG1012	belongs to the aldehyde dehydrogenase family
NF392_RS01965	COG2514	catechol 2,3-dioxygenase activity
NF392_RS01980	COG1012	belongs to the aldehyde dehydrogenase family
NF392_RS01985	COG3949	Membrane
NF392_RS01995	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NF392_RS02000	COG0586	Pfam SNARE associated Golgi protein
NF392_RS02010	COG2022	thiamine diphosphate biosynthetic process
NF392_RS02020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NF392_RS02030	COG2271	Major facilitator Superfamily
NF392_RS02045	COG4876	unkown
NF392_RS02050	COG2357	RelA SpoT domain protein
NF392_RS02065	COG1802	Transcriptional regulator
NF392_RS02070	COG1070	Carbohydrate kinase
NF392_RS02075	COG2610	gluconate transmembrane transporter activity
NF392_RS02080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NF392_RS02085	COG1216	Glycosyl transferase, family 2
NF392_RS02100	COG4221	oxidoreductase activity
NF392_RS02105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF392_RS02110	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NF392_RS02120	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NF392_RS02125	COG1028	Short-chain dehydrogenase reductase Sdr
NF392_RS02135	COG1363	Peptidase, m42
NF392_RS02140	COG4808	Protein conserved in bacteria
NF392_RS02145	COG0069	glutamate synthase activity
NF392_RS02160	COG4619	ABC transporter
NF392_RS02165	COG0390	transport system, permease component
NF392_RS02170	COG2814	Major facilitator Superfamily
NF392_RS02175	COG2272	Belongs to the type-B carboxylesterase lipase family
NF392_RS02180	COG0531	amino acid
NF392_RS02185	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
NF392_RS02190	COG1063	alcohol dehydrogenase
NF392_RS02210	COG1174	glycine betaine transport
NF392_RS02215	COG1346	cytolysis
NF392_RS02220	COG1380	Effector of murein hydrolase LrgA
NF392_RS02230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NF392_RS02245	COG0706	membrane insertase activity
NF392_RS02255	COG0531	amino acid
NF392_RS02265	COG1113	amino acid transport
NF392_RS02285	COG2814	Major facilitator Superfamily
NF392_RS02295	COG1929	Belongs to the glycerate kinase type-1 family
NF392_RS02310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NF392_RS02315	COG0741	lytic transglycosylase activity
NF392_RS02320	COG0588	phosphoglycerate mutase activity
NF392_RS02330	COG2814	Major facilitator Superfamily
NF392_RS02335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NF392_RS02340	COG0765	amino acid transport
NF392_RS02345	COG1126	abc transporter atp-binding protein
NF392_RS02355	COG2348	transferase activity, transferring amino-acyl groups
NF392_RS02390	COG0454	-acetyltransferase
NF392_RS02395	COG0747	negative chemotaxis
NF392_RS02405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NF392_RS02410	COG2146	nitrite reductase [NAD(P)H] activity
NF392_RS02420	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NF392_RS02425	COG1140	nitrate reductase beta subunit
NF392_RS02435	COG2181	nitrate reductase activity
NF392_RS02445	COG4585	Histidine kinase
NF392_RS02450	COG2197	response regulator
NF392_RS02455	COG2223	nitrite transmembrane transporter activity
NF392_RS02470	COG0778	Nitroreductase
NF392_RS02490	COG3871	stress protein (general stress protein 26)
NF392_RS02495	COG4753	response regulator
NF392_RS02495	COG2207	Transcriptional regulator
NF392_RS02505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF392_RS02505	COG1263	PTS System
NF392_RS02540	COG0492	ferredoxin-NADP+ reductase activity
NF392_RS02550	COG0604	alcohol dehydrogenase
NF392_RS02555	COG2822	iron ion transport
NF392_RS02560	COG2837	iron assimilation
NF392_RS02565	COG0672	)-iron permease
NF392_RS02570	COG0805	protein transport
NF392_RS02575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NF392_RS02585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NF392_RS02585	COG0463	Glycosyl transferase, family 2
NF392_RS02595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NF392_RS02600	COG1620	l-lactate permease
NF392_RS02610	COG0579	oxidoreductase
NF392_RS02615	COG5002	protein histidine kinase activity
NF392_RS02615	COG3850	Histidine kinase
NF392_RS02620	COG0745	RESPONSE REGULATOR receiver
NF392_RS02625	COG0577	efflux transmembrane transporter activity
NF392_RS02630	COG1136	(ABC) transporter
NF392_RS02645	COG4640	response to antibiotic
NF392_RS02650	COG2814	Major facilitator Superfamily
NF392_RS02660	COG1566	PFAM secretion protein HlyD family protein
NF392_RS02665	COG2814	Major facilitator Superfamily
NF392_RS02690	COG0598	Magnesium transport protein CorA
NF392_RS02695	COG1304	FMN binding
NF392_RS02700	COG0786	glutamate:sodium symporter activity
NF392_RS02720	COG2094	Belongs to the DNA glycosylase MPG family
NF392_RS02725	COG3152	Membrane
NF392_RS02740	COG1069	ribulokinase activity
NF392_RS02745	COG4152	abc transporter atp-binding protein
NF392_RS02750	COG1668	transmembrane transport
NF392_RS02755	COG1742	UPF0060 membrane protein
NF392_RS02765	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NF392_RS02770	COG1266	CAAX protease self-immunity
NF392_RS02775	COG0010	Belongs to the arginase family
NF392_RS02780	COG0583	DNA-binding transcription factor activity
NF392_RS02795	COG0659	secondary active sulfate transmembrane transporter activity
NF392_RS02800	COG1473	amidohydrolase
NF392_RS02805	COG1028	Short-chain dehydrogenase reductase Sdr
NF392_RS02825	COG1737	Transcriptional regulator
NF392_RS02830	COG1263	PTS System
NF392_RS02830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF392_RS02840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NF392_RS02860	COG1113	amino acid transport
NF392_RS02870	COG1263	PTS System
NF392_RS02870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF392_RS02875	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NF392_RS02905	COG1316	TRANSCRIPTIONal
NF392_RS02935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NF392_RS02940	COG2076	Multidrug Resistance protein
NF392_RS02945	COG2076	Multidrug Resistance protein
NF392_RS02950	COG3942	CHAP domain
NF392_RS02965	COG1757	Na H antiporter
NF392_RS02970	COG3942	CHAP domain
NF392_RS02995	COG0829	nickel cation binding
NF392_RS03010	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NF392_RS03015	COG0804	urea catabolic process
NF392_RS03025	COG0831	urea catabolic process
NF392_RS03030	COG4413	Urea transporter
NF392_RS03035	COG1960	acyl-CoA dehydrogenase activity
NF392_RS03040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF392_RS03050	COG1268	BioY protein
NF392_RS03065	COG0725	ABC transporter, periplasmic molybdate-binding protein
NF392_RS03070	COG4149	molybdate abc transporter
NF392_RS03075	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NF392_RS03080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NF392_RS03085	COG0521	Mo-molybdopterin cofactor biosynthetic process
NF392_RS03090	COG0315	cyclic pyranopterin monophosphate synthase activity
NF392_RS03095	COG0303	'Molybdopterin
NF392_RS03100	COG1763	Mo-molybdopterin cofactor biosynthetic process
NF392_RS03115	COG0746	molybdenum cofactor guanylyltransferase activity
NF392_RS03120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NF392_RS03130	COG2814	Major facilitator Superfamily
NF392_RS03150	COG2348	transferase activity, transferring amino-acyl groups
NF392_RS03155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NF392_RS03180	COG4975	Glucose uptake
NF392_RS03190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NF392_RS03190	COG0551	DNA topoisomerase type I activity
NF392_RS03195	COG2252	PERMEase
NF392_RS03210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NF392_RS03215	COG0088	Forms part of the polypeptide exit tunnel
NF392_RS03220	COG0089	rRNA binding
NF392_RS03225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NF392_RS03230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NF392_RS03240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NF392_RS03245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NF392_RS03255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NF392_RS03260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NF392_RS03265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NF392_RS03270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NF392_RS03275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NF392_RS03280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NF392_RS03285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NF392_RS03290	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NF392_RS03295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NF392_RS03300	COG1841	ribosomal large subunit assembly
NF392_RS03305	COG0200	Binds to the 23S rRNA
NF392_RS03310	COG0201	protein transport
NF392_RS03315	COG0563	adenylate kinase activity
NF392_RS03320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NF392_RS03325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NF392_RS03330	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NF392_RS03340	COG0202	RNA polymerase activity
NF392_RS03345	COG0203	ribosomal protein L17
NF392_RS03350	COG1122	ATPase activity
NF392_RS03355	COG1122	ATPase activity
NF392_RS03365	COG0101	tRNA pseudouridine synthase activity
NF392_RS03370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NF392_RS03375	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NF392_RS03380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NF392_RS03385	COG1349	DNA-binding transcription factor activity
NF392_RS03390	COG0698	ribose 5-phosphate isomerase
NF392_RS03430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF392_RS03435	COG2130	NADP-dependent
NF392_RS03440	COG0604	alcohol dehydrogenase
NF392_RS03445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NF392_RS03460	COG1302	Protein conserved in bacteria
NF392_RS03465	COG4264	IucA IucC family
NF392_RS03470	COG2814	Major facilitator Superfamily
NF392_RS03475	COG4264	IucA IucC family
NF392_RS03480	COG3457	Alanine racemase
NF392_RS03485	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NF392_RS03490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF392_RS03495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF392_RS03500	COG3314	Sporulation integral membrane protein YlbJ
NF392_RS03505	COG2329	Antibiotic biosynthesis monooxygenase
NF392_RS03515	COG1988	membrane-bound metal-dependent
NF392_RS03520	COG4284	Utp--glucose-1-phosphate uridylyltransferase
NF392_RS03525	COG1272	protein, Hemolysin III
NF392_RS03540	COG2814	Major facilitator Superfamily
NF392_RS03545	COG0489	protein tyrosine kinase activity
NF392_RS03600	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NF392_RS03610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NF392_RS03625	COG3711	transcriptional antiterminator
NF392_RS03635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NF392_RS03640	COG0561	phosphatase activity
NF392_RS03660	COG0640	Transcriptional regulator
NF392_RS03665	COG0702	epimerase
NF392_RS03670	COG1482	cell wall glycoprotein biosynthetic process
NF392_RS03690	COG0783	Belongs to the Dps family
NF392_RS03695	COG0813	purine-nucleoside phosphorylase activity
NF392_RS03700	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NF392_RS03705	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NF392_RS03710	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NF392_RS03725	COG1854	S-ribosylhomocysteine lyase activity
NF392_RS03745	COG5146	pantothenate kinase activity
NF392_RS03755	COG3343	RNA polymerase activity
NF392_RS03760	COG0504	CTP synthase activity
NF392_RS03770	COG0191	fructose-bisphosphate aldolase activity
NF392_RS03775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NF392_RS03785	COG1012	belongs to the aldehyde dehydrogenase family
NF392_RS03790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NF392_RS03795	COG0254	rRNA binding
NF392_RS03800	COG1435	thymidine kinase activity
NF392_RS03810	COG2890	protein-(glutamine-N5) methyltransferase activity
NF392_RS03815	COG0009	L-threonylcarbamoyladenylate synthase
NF392_RS03820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NF392_RS03825	COG4475	Protein of unknown function (DUF436)
NF392_RS03830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NF392_RS03835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NF392_RS03840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NF392_RS03850	COG0356	it plays a direct role in the translocation of protons across the membrane
NF392_RS03860	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NF392_RS03865	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NF392_RS03870	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NF392_RS03875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NF392_RS03880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NF392_RS03885	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NF392_RS03895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NF392_RS03900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NF392_RS03910	COG0629	single-stranded DNA binding
NF392_RS03915	COG1388	LysM domain
NF392_RS03920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NF392_RS03930	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NF392_RS03935	COG0352	thiamine-phosphate diphosphorylase activity
NF392_RS03940	COG0706	membrane insertase activity
NF392_RS03945	COG1418	mRNA catabolic process
NF392_RS03950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NF392_RS03955	COG1937	Protein conserved in bacteria
NF392_RS03970	COG0772	Belongs to the SEDS family
NF392_RS03975	COG1181	Belongs to the D-alanine--D-alanine ligase family
NF392_RS03980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NF392_RS03985	COG0513	Belongs to the DEAD box helicase family
NF392_RS04000	COG3402	PFAM membrane-flanked domain
NF392_RS04010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NF392_RS04020	COG2337	Toxic component of a toxin-antitoxin (TA) module
NF392_RS04025	COG2208	phosphoserine phosphatase activity
NF392_RS04040	COG1191	sigma factor activity
NF392_RS04045	COG2183	response to ionizing radiation
NF392_RS04050	COG3091	SprT-like family
NF392_RS04085	COG0066	3-isopropylmalate dehydratase activity
NF392_RS04090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NF392_RS04095	COG0473	3-isopropylmalate dehydrogenase activity
NF392_RS04100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NF392_RS04105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NF392_RS04115	COG0028	Belongs to the TPP enzyme family
NF392_RS04120	COG0129	dihydroxy-acid dehydratase activity
NF392_RS04125	COG0802	atpase or kinase
NF392_RS04130	COG1214	PFAM Peptidase M22, glycoprotease
NF392_RS04135	COG0456	acetyltransferase
NF392_RS04140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NF392_RS04145	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NF392_RS04150	COG0488	(ABC) transporter
NF392_RS04155	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NF392_RS04165	COG2391	methyltransferase activity
NF392_RS04170	COG0425	Belongs to the sulfur carrier protein TusA family
NF392_RS04175	COG0004	ammonium transporteR
NF392_RS04180	COG1609	Transcriptional regulator
NF392_RS04185	COG1621	beta-fructofuranosidase activity
NF392_RS04190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NF392_RS04195	COG3279	Response regulator of the LytR AlgR family
NF392_RS04200	COG3290	protein histidine kinase activity
NF392_RS04235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NF392_RS04240	COG0459	protein refolding
NF392_RS04270	COG1725	Transcriptional regulator
NF392_RS04285	COG1131	(ABC) transporter
NF392_RS04335	COG4974	Belongs to the 'phage' integrase family
NF392_RS04365	COG3682	Transcriptional regulator
NF392_RS04375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NF392_RS04380	COG2706	6-phosphogluconolactonase activity
NF392_RS04385	COG1012	belongs to the aldehyde dehydrogenase family
NF392_RS04390	COG1227	inorganic diphosphatase activity
NF392_RS04395	COG1335	isochorismatase
NF392_RS04405	COG0077	Prephenate dehydratase
NF392_RS04415	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NF392_RS04420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NF392_RS04425	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NF392_RS04435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NF392_RS04440	COG4496	protein, YerC YecD
NF392_RS04445	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NF392_RS04450	COG0210	DNA helicase
NF392_RS04455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NF392_RS04465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NF392_RS04470	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NF392_RS04475	COG0154	amidase activity
NF392_RS04480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NF392_RS04485	COG1597	lipid kinase activity
NF392_RS04490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NF392_RS04500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NF392_RS04510	COG1528	Iron-storage protein
NF392_RS04530	COG4129	membrane
NF392_RS04535	COG0024	Methionine aminopeptidase
NF392_RS04555	COG2197	response regulator
NF392_RS04560	COG1295	ribonuclease BN
NF392_RS04570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NF392_RS04575	COG4840	Belongs to the UPF0435 family
NF392_RS04580	COG2309	aminopeptidase activity
NF392_RS04585	COG1607	acyl-coa hydrolase
NF392_RS04590	COG0535	radical SAM domain protein
NF392_RS04600	COG0693	protein deglycase activity
NF392_RS04605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF392_RS04610	COG2137	regulation of response to DNA damage stimulus
NF392_RS04620	COG1388	LysM domain
NF392_RS04620	COG1134	teichoic acid transport
NF392_RS04630	COG1988	membrane-bound metal-dependent
NF392_RS04640	COG3557	Belongs to the UPF0374 family
NF392_RS04650	COG4129	membrane
NF392_RS04655	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NF392_RS04660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NF392_RS04665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NF392_RS04670	COG0735	belongs to the Fur family
NF392_RS04845	COG0765	amino acid transport
NF392_RS04850	COG1126	abc transporter atp-binding protein
NF392_RS04855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NF392_RS04865	COG0363	glucosamine-6-phosphate deaminase activity
NF392_RS04880	COG0114	fumarate hydratase activity
NF392_RS04885	COG0564	pseudouridine synthase activity
NF392_RS04890	COG2203	Gaf domain
NF392_RS04890	COG4585	Histidine kinase
NF392_RS04895	COG2197	response regulator
NF392_RS04905	COG4399	Belongs to the UPF0754 family
NF392_RS04910	COG3679	Belongs to the UPF0342 family
NF392_RS04915	COG0420	3'-5' exonuclease activity
NF392_RS04925	COG3481	metal-dependent phosphohydrolase, HD sub domain
NF392_RS04935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NF392_RS04950	COG0537	adenosine 5'-monophosphoramidase activity
NF392_RS04955	COG1131	(ABC) transporter
NF392_RS04960	COG4473	ABC transporter
NF392_RS04965	COG2329	Antibiotic biosynthesis monooxygenase
NF392_RS04970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NF392_RS04975	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NF392_RS04980	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NF392_RS05030	COG0318	PFAM AMP-dependent synthetase and ligase
NF392_RS05045	COG0494	nUDIX hydrolase
NF392_RS05050	COG1506	peptidase
NF392_RS05060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NF392_RS05070	COG0656	L-ascorbic acid biosynthetic process
NF392_RS05075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NF392_RS05080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NF392_RS05090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NF392_RS05105	COG1595	DNA-templated transcription, initiation
NF392_RS05115	COG3266	domain, Protein
NF392_RS05115	COG5632	N-Acetylmuramoyl-L-alanine amidase
NF392_RS05115	COG4193	domain, Protein
NF392_RS05125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NF392_RS05125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NF392_RS05135	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NF392_RS05135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NF392_RS05140	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NF392_RS05145	COG0506	proline dehydrogenase activity
NF392_RS05150	COG2267	carboxylic ester hydrolase activity
NF392_RS05160	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NF392_RS05165	COG1242	4 iron, 4 sulfur cluster binding
NF392_RS05170	COG2814	Major facilitator Superfamily
NF392_RS05175	COG0495	leucyl-tRNA aminoacylation
NF392_RS05180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF392_RS05190	COG2081	HI0933 family
NF392_RS05195	COG2244	polysaccharide biosynthetic process
NF392_RS05200	COG1187	pseudouridine synthase activity
NF392_RS05210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NF392_RS05215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF392_RS05220	COG0510	thiamine kinase activity
NF392_RS05225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NF392_RS05230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF392_RS05240	COG1363	Peptidase, m42
NF392_RS05245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF392_RS05250	COG4848	Belongs to the UPF0354 family
NF392_RS05255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF392_RS05260	COG1674	ftsk spoiiie
NF392_RS05265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NF392_RS05270	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NF392_RS05280	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NF392_RS05280	COG1605	Chorismate mutase
NF392_RS05285	COG1609	Transcriptional regulator
NF392_RS05295	COG0454	-acetyltransferase
NF392_RS05300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NF392_RS05305	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NF392_RS05310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF392_RS05315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NF392_RS05325	COG2814	Major facilitator Superfamily
NF392_RS05330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NF392_RS05335	COG0204	Acyl-transferase
NF392_RS05340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NF392_RS05340	COG1263	PTS System
NF392_RS05350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NF392_RS05360	COG1764	response to oxidative stress
NF392_RS05365	COG0584	glycerophosphoryl diester phosphodiesterase
NF392_RS05370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NF392_RS05375	COG1956	GAF domain-containing protein
NF392_RS05380	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NF392_RS05385	COG1104	cysteine desulfurase activity
NF392_RS05390	COG0301	tRNA thio-modification
NF392_RS05400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NF392_RS05405	COG0827	DNA restriction-modification system
NF392_RS05410	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NF392_RS05415	COG0589	response to stress
NF392_RS05425	COG0006	proline dipeptidase activity
NF392_RS05430	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NF392_RS05440	COG4109	DRTGG domain
NF392_RS05445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NF392_RS05450	COG0587	DNA-directed DNA polymerase activity
NF392_RS05455	COG0281	malic enzyme
NF392_RS05460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NF392_RS05465	COG0825	malonyl-CoA metabolic process
NF392_RS05470	COG0205	6-phosphofructokinase activity
NF392_RS05475	COG0469	pyruvate kinase activity
NF392_RS05480	COG1113	amino acid transport
NF392_RS05485	COG0372	Belongs to the citrate synthase family
NF392_RS05490	COG0538	isocitrate dehydrogenase activity
NF392_RS05495	COG0745	RESPONSE REGULATOR receiver
NF392_RS05500	COG5002	protein histidine kinase activity
NF392_RS05505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF392_RS05505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF392_RS05515	COG0237	dephospho-CoA kinase activity
NF392_RS05520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NF392_RS05525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NF392_RS05535	COG1484	DNA-dependent DNA replication
NF392_RS05540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NF392_RS05545	COG0833	amino acid
NF392_RS05550	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NF392_RS05555	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NF392_RS05560	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NF392_RS05565	COG4112	unkown
NF392_RS05575	COG0544	peptidyl-prolyl cis-trans isomerase activity
NF392_RS05580	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NF392_RS05585	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NF392_RS05590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NF392_RS05595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NF392_RS05600	COG0181	hydroxymethylbilane synthase activity
NF392_RS05610	COG0113	porphobilinogen synthase activity
NF392_RS05615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NF392_RS05625	COG2818	Glycosylase
NF392_RS05630	COG0525	valine-tRNA ligase activity
NF392_RS05635	COG0285	dihydrofolate synthase activity
NF392_RS05645	COG2003	Belongs to the UPF0758 family
NF392_RS05680	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NF392_RS05685	COG2868	ribosomal protein
NF392_RS05690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NF392_RS05695	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NF392_RS05700	COG4492	Belongs to the UPF0735 family
NF392_RS05705	COG0632	four-way junction helicase activity
NF392_RS05710	COG2255	four-way junction helicase activity
NF392_RS05715	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NF392_RS05725	COG1862	Preprotein translocase
NF392_RS05730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NF392_RS05730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NF392_RS05735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NF392_RS05735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NF392_RS05745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NF392_RS05750	COG1490	D-aminoacyl-tRNA deacylase activity
NF392_RS05755	COG0860	N-Acetylmuramoyl-L-alanine amidase
NF392_RS05765	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NF392_RS05775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NF392_RS05780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NF392_RS05785	COG1959	2 iron, 2 sulfur cluster binding
NF392_RS05795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NF392_RS05800	COG1104	cysteine desulfurase activity
NF392_RS05805	COG0482	sulfurtransferase activity
NF392_RS05815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NF392_RS05820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NF392_RS05825	COG4472	Bacterial protein of unknown function (DUF965)
NF392_RS05830	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NF392_RS05835	COG3906	Belongs to the UPF0473 family
NF392_RS05845	COG0826	peptidase U32
NF392_RS05850	COG0826	peptidase U32
NF392_RS05855	COG0572	uridine kinase
NF392_RS05860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NF392_RS05865	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NF392_RS05870	COG1984	allophanate hydrolase subunit 2
NF392_RS05875	COG0511	ligase activity, forming carbon-carbon bonds
NF392_RS05880	COG0439	Biotin carboxylase
NF392_RS05885	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NF392_RS05890	COG1914	H( )-stimulated, divalent metal cation uptake system
NF392_RS05895	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NF392_RS05900	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NF392_RS05905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NF392_RS05915	COG1534	Rna-binding protein
NF392_RS05920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NF392_RS05925	COG1713	HD superfamily hydrolase involved in NAD metabolism
NF392_RS05930	COG0799	negative regulation of ribosome biogenesis
NF392_RS05935	COG2226	methyltransferase
NF392_RS05940	COG1596	polysaccharide export
NF392_RS05940	COG1555	photosystem II stabilization
NF392_RS05945	COG2131	deaminase
NF392_RS05950	COG0658	competence protein
NF392_RS05950	COG2333	competence protein COMEC
NF392_RS05955	COG1466	dna polymerase III delta subunit
NF392_RS05960	COG0268	Binds directly to 16S ribosomal RNA
NF392_RS05965	COG0481	GTPase activity
NF392_RS05970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NF392_RS05975	COG1420	regulation of RNA biosynthetic process
NF392_RS05980	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NF392_RS05985	COG0443	Heat shock 70 kDa protein
NF392_RS05990	COG0484	heat shock protein binding
NF392_RS05995	COG2264	protein methyltransferase activity
NF392_RS06000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NF392_RS06005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NF392_RS06015	COG1030	water channel activity
NF392_RS06020	COG4864	UPF0365 protein
NF392_RS06030	COG1702	phosphate starvation-inducible protein PhoH
NF392_RS06035	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NF392_RS06045	COG0295	cytidine deaminase activity
NF392_RS06050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NF392_RS06055	COG1381	Involved in DNA repair and RecF pathway recombination
NF392_RS06060	COG0423	glycine-tRNA ligase activity
NF392_RS06065	COG0517	IMP dehydrogenase activity
NF392_RS06070	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NF392_RS06075	COG0358	DNA primase activity
NF392_RS06080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NF392_RS06085	COG2384	SAM-dependent methyltransferase
NF392_RS06090	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NF392_RS06095	COG0513	Belongs to the DEAD box helicase family
NF392_RS06100	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NF392_RS06105	COG1121	(ABC) transporter
NF392_RS06110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NF392_RS06125	COG0768	penicillin binding
NF392_RS06130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NF392_RS06135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NF392_RS06145	COG4483	Protein conserved in bacteria
NF392_RS06150	COG1940	carbohydrate kinase activity
NF392_RS06155	COG0011	TIGRFAM Protein of
NF392_RS06160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NF392_RS06165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NF392_RS06170	COG1459	type II secretion system
NF392_RS06175	COG4537	Required for transformation and DNA binding
NF392_RS06200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NF392_RS06205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NF392_RS06220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NF392_RS06225	COG0095	Lipoate-protein ligase
NF392_RS06240	COG0006	proline dipeptidase activity
NF392_RS06245	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NF392_RS06250	COG0511	ligase activity, forming carbon-carbon bonds
NF392_RS06255	COG0439	Biotin carboxylase
NF392_RS06260	COG1302	Protein conserved in bacteria
NF392_RS06265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NF392_RS06270	COG1570	exodeoxyribonuclease VII activity
NF392_RS06275	COG1722	exodeoxyribonuclease VII activity
NF392_RS06285	COG1438	arginine binding
NF392_RS06290	COG0497	DNA recombination
NF392_RS06295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NF392_RS06300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NF392_RS06305	COG0022	dehydrogenase e1 component
NF392_RS06310	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF392_RS06320	COG4129	membrane
NF392_RS06330	COG2195	Cleaves the N-terminal amino acid of tripeptides
NF392_RS06335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NF392_RS06340	COG0366	Alpha amylase catalytic
NF392_RS06350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NF392_RS06355	COG1234	tRNA 3'-trailer cleavage
NF392_RS06360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NF392_RS06365	COG0300	oxidoreductase activity
NF392_RS06375	COG0667	Aldo Keto reductase
NF392_RS06380	COG0494	nUDIX hydrolase
NF392_RS06385	COG0735	belongs to the Fur family
NF392_RS06390	COG4974	Belongs to the 'phage' integrase family
NF392_RS06400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NF392_RS06405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NF392_RS06410	COG1187	pseudouridine synthase activity
NF392_RS06415	COG0745	RESPONSE REGULATOR receiver
NF392_RS06430	COG1141	Ferredoxin
NF392_RS06440	COG0514	ATP-dependent DNA helicase (RecQ)
NF392_RS06445	COG1388	LysM domain
NF392_RS06445	COG1388	LysM domain
NF392_RS06450	COG0492	ferredoxin-NADP+ reductase activity
NF392_RS06460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NF392_RS06465	COG0539	negative regulation of cytoplasmic translation
NF392_RS06470	COG1160	GTP binding
NF392_RS06475	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NF392_RS06490	COG2226	methyltransferase
NF392_RS06495	COG0142	geranyltranstransferase activity
NF392_RS06500	COG0105	UTP biosynthetic process
NF392_RS06505	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NF392_RS06510	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NF392_RS06515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NF392_RS06525	COG5582	Belongs to the UPF0302 family
NF392_RS06530	COG4347	Protein of unknown function (DUF1405)
NF392_RS06535	COG2738	Putative neutral zinc metallopeptidase
NF392_RS06540	COG1694	Mazg nucleotide pyrophosphohydrolase
NF392_RS06545	COG0438	transferase activity, transferring glycosyl groups
NF392_RS06550	COG0617	tRNA 3'-terminal CCA addition
NF392_RS06560	COG1199	ATP-dependent helicase activity
NF392_RS06560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NF392_RS06565	COG0017	Asparaginyl-tRNA synthetase
NF392_RS06570	COG3935	DnaD domain protein
NF392_RS06575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NF392_RS06585	COG4499	WXG100 protein secretion system (Wss), protein YukC
NF392_RS06585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NF392_RS06590	COG3331	DNA recombination
NF392_RS06600	COG4474	Belongs to the UPF0398 family
NF392_RS06605	COG3599	regulation of cell shape
NF392_RS06615	COG0116	Belongs to the methyltransferase superfamily
NF392_RS06625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NF392_RS06630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NF392_RS06635	COG1196	nuclear chromosome segregation
NF392_RS06635	COG4372	Transposase
NF392_RS06635	COG1511	domain protein
NF392_RS06640	COG0328	RNA-DNA hybrid ribonuclease activity
NF392_RS06645	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NF392_RS06655	COG1413	lyase activity
NF392_RS06660	COG1413	lyase activity
NF392_RS06690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NF392_RS06695	COG2190	(PTS) system
NF392_RS06700	COG4479	Belongs to the UPF0346 family
NF392_RS06705	COG0793	Belongs to the peptidase S41A family
NF392_RS06715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NF392_RS06720	COG0671	phosphoesterase, PA-phosphatase related
NF392_RS06725	COG3842	ATPase activity
NF392_RS06730	COG4209	transmembrane transport
NF392_RS06740	COG0395	ABC-type sugar transport system, permease component
NF392_RS06750	COG0534	Mate efflux family protein
NF392_RS06755	COG1349	DNA-binding transcription factor activity
NF392_RS06765	COG0745	RESPONSE REGULATOR receiver
NF392_RS06770	COG5002	protein histidine kinase activity
NF392_RS06775	COG0567	Dehydrogenase, E1 component
NF392_RS06790	COG1131	(ABC) transporter
NF392_RS06810	COG0714	Associated with various cellular activities
NF392_RS06815	COG4548	von Willebrand factor, type A
NF392_RS06820	COG1114	Component of the transport system for branched-chain amino acids
NF392_RS06825	COG3853	Toxic anion resistance protein (TelA)
NF392_RS06835	COG1254	Belongs to the acylphosphatase family
NF392_RS06845	COG1278	Cold shock
NF392_RS06860	COG1473	amidohydrolase
NF392_RS06870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NF392_RS06875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NF392_RS06880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NF392_RS06885	COG0527	aspartate kinase activity
NF392_RS06890	COG0488	(ABC) transporter
NF392_RS06895	COG2996	Protein conserved in bacteria
NF392_RS06900	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NF392_RS06905	COG0573	inorganic phosphate transmembrane transporter activity
NF392_RS06910	COG0581	inorganic phosphate transmembrane transporter activity
NF392_RS06915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NF392_RS06920	COG0704	Plays a role in the regulation of phosphate uptake
NF392_RS06925	COG1164	Oligoendopeptidase f
NF392_RS06960	COG2348	transferase activity, transferring amino-acyl groups
NF392_RS06965	COG2348	transferase activity, transferring amino-acyl groups
NF392_RS06975	COG0159	tryptophan synthase activity
NF392_RS06985	COG0135	phosphoribosylanthranilate isomerase activity
NF392_RS06990	COG0134	indole-3-glycerol-phosphate synthase activity
NF392_RS06995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NF392_RS07000	COG0512	Glutamine amidotransferase of anthranilate synthase
NF392_RS07005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NF392_RS07010	COG1363	Peptidase, m42
NF392_RS07015	COG0287	Prephenate dehydrogenase
NF392_RS07020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NF392_RS07025	COG1942	4-Oxalocrotonate Tautomerase
NF392_RS07040	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NF392_RS07040	COG0392	lysyltransferase activity
NF392_RS07045	COG0628	permease
NF392_RS07050	COG3711	transcriptional antiterminator
NF392_RS07055	COG1115	amino acid carrier protein
NF392_RS07060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NF392_RS07065	COG0187	DNA topoisomerase II activity
NF392_RS07070	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NF392_RS07080	COG0824	Thioesterase
NF392_RS07085	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NF392_RS07090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NF392_RS07095	COG1970	mechanosensitive ion channel activity
NF392_RS07100	COG0419	ATPase involved in DNA repair
NF392_RS07105	COG0420	3'-5' exonuclease activity
NF392_RS07110	COG4846	Membrane protein involved in cytochrome C biogenesis
NF392_RS07120	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NF392_RS07125	COG4224	UPF0291 protein
NF392_RS07135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NF392_RS07140	COG2340	Cysteine-rich secretory protein family
NF392_RS07145	COG0516	GMP reductase activity
NF392_RS07150	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NF392_RS07160	COG0753	catalase activity
NF392_RS07165	COG0833	amino acid
NF392_RS07180	COG0083	homoserine kinase activity
NF392_RS07185	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NF392_RS07190	COG0460	homoserine dehydrogenase
NF392_RS07195	COG0527	aspartate kinase activity
NF392_RS07210	COG1525	nuclease
NF392_RS07225	COG2197	response regulator
NF392_RS07230	COG4585	Histidine kinase
NF392_RS07240	COG1131	(ABC) transporter
NF392_RS07245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NF392_RS07305	COG0789	Transcriptional regulator
NF392_RS07310	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NF392_RS07315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NF392_RS07320	COG0386	Belongs to the glutathione peroxidase family
NF392_RS07325	COG1923	regulation of RNA biosynthetic process
NF392_RS07330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NF392_RS07340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NF392_RS07345	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NF392_RS07350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NF392_RS07360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NF392_RS07365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NF392_RS07375	COG4550	Control of competence regulator ComK, YlbF/YmcA
NF392_RS07380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NF392_RS07390	COG4195	phage-related replication protein
NF392_RS07395	COG1013	pyruvate-flavodoxin oxidoreductase activity
NF392_RS07400	COG0674	pyruvate-flavodoxin oxidoreductase activity
NF392_RS07400	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NF392_RS07405	COG1692	metallophosphoesterase
NF392_RS07415	COG1418	mRNA catabolic process
NF392_RS07420	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NF392_RS07425	COG1058	Belongs to the CinA family
NF392_RS07425	COG1546	Belongs to the CinA family
NF392_RS07430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NF392_RS07445	COG0300	oxidoreductase activity
NF392_RS07450	COG0612	Peptidase, M16
NF392_RS07455	COG0612	Peptidase, M16
NF392_RS07460	COG2188	Transcriptional regulator
NF392_RS07465	COG1674	ftsk spoiiie
NF392_RS07470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NF392_RS07475	COG1185	polyribonucleotide nucleotidyltransferase activity
NF392_RS07480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NF392_RS07485	COG0196	riboflavin kinase activity
NF392_RS07490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NF392_RS07495	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NF392_RS07500	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NF392_RS07505	COG1358	cellular component organization or biogenesis
NF392_RS07510	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NF392_RS07515	COG0195	Participates in both transcription termination and antitermination
NF392_RS07520	COG0779	Required for maturation of 30S ribosomal subunits
NF392_RS07525	COG2176	DNA-directed DNA polymerase activity
NF392_RS07530	COG0442	prolyl-tRNA aminoacylation
NF392_RS07540	COG4589	Belongs to the CDS family
NF392_RS07545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NF392_RS07550	COG0233	cytoplasmic translational termination
NF392_RS07555	COG0528	UMP kinase activity
NF392_RS07560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NF392_RS07565	COG0052	Belongs to the universal ribosomal protein uS2 family
NF392_RS07580	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NF392_RS07585	COG4974	Belongs to the 'phage' integrase family
NF392_RS07590	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NF392_RS07595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NF392_RS07600	COG0758	DNA mediated transformation
NF392_RS07605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NF392_RS07610	COG0045	succinate-CoA ligase (ADP-forming) activity
NF392_RS07615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NF392_RS07625	COG4485	Bacterial membrane protein, YfhO
NF392_RS07645	COG0335	large ribosomal subunit rRNA binding
NF392_RS07650	COG0336	Belongs to the RNA methyltransferase TrmD family
NF392_RS07655	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NF392_RS07660	COG0228	four-way junction DNA binding
NF392_RS07665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NF392_RS07670	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NF392_RS07675	COG0552	protein localization to endoplasmic reticulum
NF392_RS07680	COG1196	nuclear chromosome segregation
NF392_RS07685	COG0571	ribonuclease III activity
NF392_RS07690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NF392_RS07695	COG1028	Short-chain dehydrogenase reductase Sdr
NF392_RS07705	COG0416	fatty acid biosynthetic process
NF392_RS07710	COG1349	DNA-binding transcription factor activity
NF392_RS07715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NF392_RS07735	COG1461	Dihydroxyacetone kinase
NF392_RS07740	COG1302	Protein conserved in bacteria
NF392_RS07745	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NF392_RS07750	COG1564	THIamine pyrophosphokinase
NF392_RS07755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NF392_RS07760	COG1162	GTPase activity
NF392_RS07765	COG2807	transmembrane transport
NF392_RS07775	COG0631	protein serine/threonine phosphatase activity
NF392_RS07780	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NF392_RS07785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NF392_RS07785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NF392_RS07790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NF392_RS07795	COG0242	peptide deformylase activity
NF392_RS07805	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NF392_RS07810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NF392_RS07815	COG1758	RNA polymerase activity
NF392_RS07820	COG0194	GDP metabolic process
NF392_RS07825	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NF392_RS07840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NF392_RS07845	COG0284	orotidine-5'-phosphate decarboxylase activity
NF392_RS07850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NF392_RS07855	COG0505	Belongs to the CarA family
NF392_RS07860	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NF392_RS07865	COG0540	Belongs to the ATCase OTCase family
NF392_RS07870	COG2233	PERMEase
NF392_RS07875	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NF392_RS07880	COG0564	pseudouridine synthase activity
NF392_RS07885	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NF392_RS07895	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NF392_RS07900	COG3599	regulation of cell shape
NF392_RS07910	COG0762	integral membrane protein
NF392_RS07915	COG1799	cell septum assembly
NF392_RS07920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NF392_RS07925	COG1496	oxidoreductase activity
NF392_RS07930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NF392_RS07935	COG0849	cell division
NF392_RS07940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NF392_RS07945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NF392_RS07950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NF392_RS07955	COG0768	penicillin binding
NF392_RS07960	COG4839	cell division protein FtsL
NF392_RS07965	COG0275	rRNA processing
NF392_RS07975	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NF392_RS07980	COG0454	-acetyltransferase
NF392_RS07985	COG1011	Hydrolase
NF392_RS08030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NF392_RS08035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NF392_RS08040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NF392_RS08045	COG1053	succinate dehydrogenase
NF392_RS08050	COG2009	succinate dehydrogenase
NF392_RS08055	COG0322	excinuclease ABC activity
NF392_RS08060	COG3118	belongs to the thioredoxin family
NF392_RS08065	COG1193	negative regulation of DNA recombination
NF392_RS08070	COG1796	DNA polymerase
NF392_RS08070	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NF392_RS08080	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NF392_RS08085	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NF392_RS08090	COG0072	phenylalanine-tRNA ligase activity
NF392_RS08090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF392_RS08095	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NF392_RS08100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NF392_RS08110	COG4509	Sortase family
NF392_RS08155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NF392_RS08170	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NF392_RS08175	COG0742	ribosomal rna small subunit methyltransferase
NF392_RS08185	COG4471	UPF0298 protein
NF392_RS08190	COG0584	glycerophosphoryl diester phosphodiesterase
NF392_RS08195	COG3679	Belongs to the UPF0342 family
NF392_RS08210	COG0109	protoheme IX farnesyltransferase activity
NF392_RS08215	COG1612	heme a metabolic process
NF392_RS08225	COG0772	Belongs to the SEDS family
NF392_RS08230	COG4838	Belongs to the UPF0358 family
NF392_RS08235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NF392_RS08240	COG4896	Protein conserved in bacteria
NF392_RS08245	COG1217	gtp-binding protein TYPA
NF392_RS08255	COG0483	inositol monophosphate 1-phosphatase activity
NF392_RS08260	COG4493	Belongs to the UPF0637 family
NF392_RS08265	COG1914	H( )-stimulated, divalent metal cation uptake system
NF392_RS08285	COG1177	transmembrane transport
NF392_RS08290	COG1176	ABC-type spermidine putrescine transport system, permease component I
NF392_RS08305	COG4476	Belongs to the UPF0223 family
NF392_RS08315	COG0508	dehydrogenase complex catalyzes the overall conversion of
NF392_RS08320	COG0022	dehydrogenase e1 component
NF392_RS08325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NF392_RS08335	COG0242	peptide deformylase activity
NF392_RS08340	COG5503	Protein of unknown function (DUF1447)
NF392_RS08345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NF392_RS08355	COG0569	domain protein
NF392_RS08360	COG1294	oxidase, subunit
NF392_RS08365	COG1271	oxidase subunit
NF392_RS08380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF392_RS08390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NF392_RS08410	COG4172	Belongs to the ABC transporter superfamily
NF392_RS08415	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NF392_RS08420	COG0151	Belongs to the GarS family
NF392_RS08425	COG0138	bifunctional purine biosynthesis protein purh
NF392_RS08430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NF392_RS08435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NF392_RS08440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NF392_RS08445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NF392_RS08450	COG0047	phosphoribosylformylglycinamidine synthase activity
NF392_RS08455	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NF392_RS08460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NF392_RS08465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NF392_RS08470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NF392_RS08475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NF392_RS08480	COG1017	nitric oxide dioxygenase activity
NF392_RS08480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NF392_RS08490	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NF392_RS08495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NF392_RS08505	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NF392_RS08520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NF392_RS08525	COG1316	TRANSCRIPTIONal
NF392_RS08550	COG3594	Acyltransferase
NF392_RS08555	COG0436	Aminotransferase
NF392_RS08560	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NF392_RS08570	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NF392_RS08575	COG1169	isochorismate synthase
NF392_RS08580	COG1575	Belongs to the MenA family. Type 1 subfamily
NF392_RS08670	COG1388	LysM domain
NF392_RS08670	COG5632	N-Acetylmuramoyl-L-alanine amidase
NF392_RS08860	COG0756	dUTP diphosphatase activity
NF392_RS08905	COG1484	DNA-dependent DNA replication
NF392_RS09040	COG4873	Protein conserved in bacteria
NF392_RS09050	COG0737	Belongs to the 5'-nucleotidase family
NF392_RS09055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NF392_RS09060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NF392_RS09065	COG0861	Integral membrane protein TerC family
NF392_RS09070	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NF392_RS09080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NF392_RS09085	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NF392_RS09090	COG2814	Major facilitator Superfamily
NF392_RS09095	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NF392_RS09100	COG2382	esterase
NF392_RS09105	COG0628	permease
NF392_RS09115	COG0569	domain protein
NF392_RS09115	COG0475	glutathione-regulated potassium exporter activity
NF392_RS09120	COG2239	Acts as a magnesium transporter
NF392_RS09125	COG0564	pseudouridine synthase activity
NF392_RS09130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NF392_RS09135	COG2357	RelA SpoT domain protein
NF392_RS09145	COG4116	CYTH
NF392_RS09150	COG2346	COG2346, Truncated hemoglobins
NF392_RS09155	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NF392_RS09160	COG1164	Oligoendopeptidase f
NF392_RS09170	COG4862	establishment of competence for transformation
NF392_RS09175	COG1393	Belongs to the ArsC family
NF392_RS09180	COG0180	Tryptophanyl-tRNA synthetase
NF392_RS09190	COG0601	transmembrane transport
NF392_RS09195	COG4608	Belongs to the ABC transporter superfamily
NF392_RS09200	COG0444	Belongs to the ABC transporter superfamily
NF392_RS09205	COG0747	negative chemotaxis
NF392_RS09215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NF392_RS09225	COG1881	PFAM PEBP family protein
NF392_RS09230	COG0542	response to heat
NF392_RS09245	COG0561	phosphatase activity
NF392_RS09250	COG0446	pyridine nucleotide-disulphide oxidoreductase
NF392_RS09260	COG0179	Fumarylacetoacetate (FAA) hydrolase
NF392_RS09265	COG1074	ATP-dependent DNA helicase activity
NF392_RS09270	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NF392_RS09285	COG0398	Pfam SNARE associated Golgi protein
NF392_RS09290	COG0166	Belongs to the GPI family
NF392_RS09295	COG0137	argininosuccinate synthase activity
NF392_RS09300	COG0165	Argininosuccinate lyase
NF392_RS09305	COG0584	glycerophosphoryl diester phosphodiesterase
NF392_RS09320	COG1902	pentaerythritol trinitrate reductase activity
NF392_RS09325	COG1098	S1 RNA binding domain
NF392_RS09330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NF392_RS09340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NF392_RS09340	COG2111	Na H antiporter
NF392_RS09345	COG2111	Na H antiporter
NF392_RS09350	COG1006	Multisubunit Na H antiporter MnhC subunit
NF392_RS09355	COG0651	ATP synthesis coupled electron transport
NF392_RS09360	COG1863	multisubunit Na H antiporter MnhE subunit
NF392_RS09365	COG2212	antiporter activity
NF392_RS09370	COG1320	monovalent cation:proton antiporter activity
NF392_RS09380	COG2050	protein possibly involved in aromatic compounds catabolism
NF392_RS09385	COG2056	Na+-H+ antiporter family
NF392_RS09390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NF392_RS09395	COG1252	NADH dehydrogenase
NF392_RS09400	COG0316	Belongs to the HesB IscA family
NF392_RS09405	COG4844	belongs to the
NF392_RS09410	COG1252	NADH dehydrogenase
NF392_RS09415	COG4837	Protein of unknown function (DUF1462)
NF392_RS09420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NF392_RS09425	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NF392_RS09435	COG1696	Membrane protein involved in D-alanine export
NF392_RS09440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NF392_RS09450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NF392_RS09455	COG0647	UMP catabolic process
NF392_RS09460	COG2445	Protein of unknown function DUF86
NF392_RS09470	COG4470	Protein conserved in bacteria
NF392_RS09475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NF392_RS09480	COG0737	Belongs to the 5'-nucleotidase family
NF392_RS09485	COG0730	response to heat
NF392_RS09490	COG1801	Protein of unknown function DUF72
NF392_RS09495	COG2070	2-Nitropropane dioxygenase
NF392_RS09500	COG1253	flavin adenine dinucleotide binding
NF392_RS09505	COG0719	Fe-S assembly protein
NF392_RS09510	COG0822	iron-sulfur transferase activity
NF392_RS09515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NF392_RS09520	COG0719	Fe-S assembly protein
NF392_RS09525	COG0396	ATPase activity
NF392_RS09545	COG1464	Belongs to the NlpA lipoprotein family
NF392_RS09550	COG2011	ABC-type metal ion transport system permease component
NF392_RS09555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NF392_RS09565	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NF392_RS09570	COG0509	glycine decarboxylation via glycine cleavage system
NF392_RS09575	COG1393	Belongs to the ArsC family
NF392_RS09580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NF392_RS09590	COG0710	3-dehydroquinate dehydratase activity
NF392_RS09595	COG1764	response to oxidative stress
NF392_RS09605	COG1279	arginine transmembrane transporter activity
NF392_RS09610	COG0406	alpha-ribazole phosphatase activity
NF392_RS09650	COG4195	phage-related replication protein
NF392_RS09670	COG1278	Cold shock
NF392_RS09690	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NF392_RS09695	COG0557	exoribonuclease II activity
NF392_RS09700	COG1647	Serine aminopeptidase, S33
NF392_RS09705	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NF392_RS09715	COG0148	phosphopyruvate hydratase activity
NF392_RS09720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NF392_RS09725	COG0149	triose-phosphate isomerase activity
NF392_RS09730	COG0126	phosphoglycerate kinase activity
NF392_RS09735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NF392_RS09740	COG2390	Transcriptional regulator
NF392_RS09755	COG1090	epimerase
NF392_RS09775	COG1481	regulation of sporulation
NF392_RS09780	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NF392_RS09785	COG1660	Displays ATPase and GTPase activities
NF392_RS09790	COG0492	ferredoxin-NADP+ reductase activity
NF392_RS09805	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NF392_RS09810	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NF392_RS09815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NF392_RS09820	COG0556	nucleotide-excision repair
NF392_RS09835	COG3942	CHAP domain
NF392_RS09835	COG1388	LysM domain
NF392_RS09845	COG0653	protein targeting
NF392_RS09855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NF392_RS09860	COG1040	competence protein
NF392_RS09865	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NF392_RS09875	COG1739	Uncharacterized protein family UPF0029
NF392_RS09880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NF392_RS09900	COG2195	Cleaves the N-terminal amino acid of tripeptides
NF392_RS09905	COG1929	Belongs to the glycerate kinase type-1 family
NF392_RS09925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NF392_RS09935	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF392_RS09940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NF392_RS09945	COG1780	Probably involved in ribonucleotide reductase function
NF392_RS09960	COG3104	oligopeptide transport
NF392_RS09965	COG1597	lipid kinase activity
NF392_RS09975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NF392_RS09980	COG1174	glycine betaine transport
NF392_RS09990	COG0514	ATP-dependent DNA helicase (RecQ)
NF392_RS09995	COG0488	(ABC) transporter
NF392_RS10005	COG1368	sulfuric ester hydrolase activity
NF392_RS10015	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NF392_RS10025	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NF392_RS10035	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NF392_RS10040	COG0720	synthase
NF392_RS10045	COG0602	queuosine metabolic process
NF392_RS10065	COG0745	RESPONSE REGULATOR receiver
NF392_RS10070	COG5002	protein histidine kinase activity
NF392_RS10075	COG0463	Glycosyl transferase, family 2
NF392_RS10080	COG0656	L-ascorbic acid biosynthetic process
NF392_RS10085	COG1253	flavin adenine dinucleotide binding
NF392_RS10090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NF392_RS10095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF392_RS10095	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NF392_RS10095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NF392_RS10100	COG1105	Belongs to the carbohydrate kinase PfkB family
NF392_RS10105	COG1349	DNA-binding transcription factor activity
NF392_RS10110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NF392_RS10140	COG0415	Belongs to the DNA photolyase family
NF392_RS10145	COG0471	metal ion transport
NF392_RS10150	COG0039	L-malate dehydrogenase activity
NF392_RS10170	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NF392_RS10175	COG4988	ABC transporter
NF392_RS10180	COG1968	undecaprenyl-diphosphatase activity
NF392_RS10190	COG1671	Belongs to the UPF0178 family
NF392_RS10195	COG1611	Belongs to the LOG family
NF392_RS10200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NF392_RS10225	COG2839	Protein conserved in bacteria
NF392_RS10235	COG0583	DNA-binding transcription factor activity
NF392_RS10250	COG0217	transcriptional regulatory protein
NF392_RS10260	COG4977	sequence-specific DNA binding
NF392_RS10260	COG1917	Cupin 2, conserved barrel domain protein
NF392_RS10270	COG3942	CHAP domain
NF392_RS10270	COG1388	LysM domain
NF392_RS10275	COG0306	phosphate transporter
NF392_RS10280	COG1392	Phosphate transport regulator
NF392_RS10285	COG0577	efflux transmembrane transporter activity
NF392_RS10290	COG1136	(ABC) transporter
NF392_RS10295	COG2205	protein histidine kinase activity
NF392_RS10300	COG0745	RESPONSE REGULATOR receiver
NF392_RS10305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NF392_RS10315	COG0657	acetylesterase activity
NF392_RS10320	COG3949	Membrane
NF392_RS10330	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NF392_RS10340	COG2376	Dihydroxyacetone kinase
NF392_RS10345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF392_RS10350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF392_RS10355	COG1120	ATPase activity
NF392_RS10360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NF392_RS10370	COG4974	Belongs to the 'phage' integrase family
NF392_RS10400	COG3682	Transcriptional regulator
NF392_RS10405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF392_RS10410	COG1132	(ABC) transporter
NF392_RS10415	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NF392_RS10425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NF392_RS10430	COG1682	transport, permease protein
NF392_RS10435	COG1134	teichoic acid transport
NF392_RS10440	COG5609	conserved protein (DUF2294)
NF392_RS10450	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NF392_RS10460	COG1321	iron dependent repressor
NF392_RS10465	COG1121	(ABC) transporter
NF392_RS10470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NF392_RS10475	COG0803	Belongs to the bacterial solute-binding protein 9 family
NF392_RS10485	COG1320	monovalent cation:proton antiporter activity
NF392_RS10490	COG2212	antiporter activity
NF392_RS10495	COG1863	multisubunit Na H antiporter MnhE subunit
NF392_RS10500	COG0651	ATP synthesis coupled electron transport
NF392_RS10505	COG1006	Multisubunit Na H antiporter MnhC subunit
NF392_RS10510	COG2111	Na H antiporter
NF392_RS10515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NF392_RS10515	COG2111	Na H antiporter
NF392_RS10550	COG0596	Alpha beta hydrolase
NF392_RS10575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NF392_RS10580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NF392_RS10590	COG0789	Transcriptional regulator
NF392_RS10600	COG0018	arginyl-trna synthetase
NF392_RS10615	COG3875	lactate racemase activity
NF392_RS10620	COG1606	tRNA processing
NF392_RS10625	COG1691	(AIR) carboxylase
NF392_RS10630	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NF392_RS10645	COG1078	dGTPase activity
NF392_RS10655	COG0655	NAD(P)H dehydrogenase (quinone) activity
NF392_RS10660	COG0667	Aldo Keto reductase
NF392_RS10670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NF392_RS10675	COG4844	belongs to the
NF392_RS10695	COG0095	Lipoate-protein ligase
NF392_RS10700	COG0280	phosphate acetyltransferase
NF392_RS10705	COG3253	May function as heme-dependent peroxidase
NF392_RS10725	COG2363	Small membrane protein
NF392_RS10735	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NF392_RS10740	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NF392_RS10745	COG0351	phosphomethylpyrimidine kinase
NF392_RS10775	COG0183	Belongs to the thiolase family
NF392_RS10780	COG0318	PFAM AMP-dependent synthetase and ligase
NF392_RS10795	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NF392_RS10800	COG0363	glucosamine-6-phosphate deaminase activity
NF392_RS10805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NF392_RS10810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NF392_RS10820	COG2271	Major facilitator Superfamily
NF392_RS10825	COG0438	transferase activity, transferring glycosyl groups
NF392_RS10830	COG0431	NADPH-dependent FMN reductase
NF392_RS10835	COG0561	phosphatase activity
NF392_RS10845	COG1428	Deoxynucleoside kinase
NF392_RS10850	COG1428	Deoxynucleoside kinase
NF392_RS10860	COG0546	phosphoglycolate phosphatase activity
NF392_RS10870	COG0582	viral genome integration into host DNA
NF392_RS10875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NF392_RS10915	COG1473	amidohydrolase
NF392_RS10920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NF392_RS10925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NF392_RS10935	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NF392_RS10945	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NF392_RS10950	COG0085	RNA polymerase activity
NF392_RS10955	COG2813	Specifically methylates the guanine in position
NF392_RS10960	COG0222	ribosome binding
NF392_RS10965	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NF392_RS10970	COG0081	regulation of translation
NF392_RS10975	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NF392_RS10980	COG0250	Participates in transcription elongation, termination and antitermination
NF392_RS10985	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NF392_RS10990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NF392_RS11000	COG3688	RNA-binding protein containing a PIN domain
NF392_RS11010	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NF392_RS11015	COG0215	cysteine-tRNA ligase activity
NF392_RS11020	COG1045	serine acetyltransferase
NF392_RS11025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NF392_RS11030	COG4956	integral membrane protein (PIN domain superfamily)
NF392_RS11035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NF392_RS11040	COG0542	response to heat
NF392_RS11045	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NF392_RS11050	COG3880	PFAM UvrB UvrC protein
NF392_RS11055	COG4463	regulation of RNA biosynthetic process
NF392_RS11060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NF392_RS11065	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NF392_RS11070	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NF392_RS11075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NF392_RS11160	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NF392_RS11165	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NF392_RS11170	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NF392_RS11180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NF392_RS11185	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NF392_RS11190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NF392_RS11195	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NF392_RS11200	COG0037	tRNA processing
NF392_RS11205	COG1098	S1 RNA binding domain
NF392_RS11215	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NF392_RS11220	COG3956	TIGRFAM MazG family protein
NF392_RS11225	COG2244	polysaccharide biosynthetic process
NF392_RS11230	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NF392_RS11240	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NF392_RS11245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NF392_RS11250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NF392_RS11255	COG2088	sporulation resulting in formation of a cellular spore
NF392_RS11260	COG0251	oxidation-reduction process
NF392_RS11265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NF392_RS11270	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NF392_RS11275	COG4466	Protein conserved in bacteria
NF392_RS11280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NF392_RS11285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NF392_RS11290	COG0084	hydrolase, TatD family'
NF392_RS11295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF392_RS11295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NF392_RS11300	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NF392_RS11305	COG2827	Endonuclease containing a URI domain
NF392_RS11310	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NF392_RS11315	COG4467	Involved in initiation control of chromosome replication
NF392_RS11320	COG1774	PSP1 C-terminal conserved region
NF392_RS11325	COG0470	DNA polymerase III
NF392_RS11330	COG3870	Protein conserved in bacteria
NF392_RS11335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NF392_RS11340	COG1982	Orn Lys Arg decarboxylase major
NF392_RS11365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NF392_RS11370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NF392_RS11375	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NF392_RS11395	COG0493	'glutamate synthase
NF392_RS11400	COG0069	glutamate synthase activity
NF392_RS11400	COG0070	glutamate synthase
NF392_RS11400	COG0067	glutamate synthase
NF392_RS11405	COG0583	DNA-binding transcription factor activity
NF392_RS11435	COG0438	transferase activity, transferring glycosyl groups
NF392_RS11440	COG3942	CHAP domain
NF392_RS11440	COG1388	LysM domain
NF392_RS11450	COG0626	cystathionine gamma-synthase activity
NF392_RS11455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NF392_RS11470	COG0733	neurotransmitter:sodium symporter activity
NF392_RS11480	COG1647	Serine aminopeptidase, S33
NF392_RS11505	COG5609	conserved protein (DUF2294)
NF392_RS11510	COG3002	Belongs to the UPF0753 family
NF392_RS11515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NF392_RS11535	COG0523	cobalamin synthesis protein
NF392_RS11545	COG2211	Major facilitator Superfamily
NF392_RS11555	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NF392_RS11580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NF392_RS11580	COG0519	Catalyzes the synthesis of GMP from XMP
NF392_RS11585	COG0516	GMP reductase activity
NF392_RS11585	COG0517	IMP dehydrogenase activity
NF392_RS11590	COG2233	PERMEase
NF392_RS11595	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NF392_RS11610	COG5183	chlorophyll binding
NF392_RS11615	COG1823	symporter activity
NF392_RS11620	COG0778	Nitroreductase
NF392_RS11630	COG0450	alkyl hydroperoxide reductase
NF392_RS11635	COG3634	alkyl hydroperoxide reductase activity
NF392_RS11655	COG1280	lysine exporter protein (LysE YggA)
NF392_RS11700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NF392_RS11710	COG0360	Binds together with S18 to 16S ribosomal RNA
NF392_RS11720	COG1011	Hydrolase
NF392_RS11745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NF392_RS11765	COG0012	GTP binding
NF392_RS11770	COG4481	Protein conserved in bacteria
NF392_RS11775	COG0668	transmembrane transport
NF392_RS11780	COG1475	DNA binding
NF392_RS11785	COG0626	cystathionine gamma-synthase activity
NF392_RS11790	COG0626	cystathionine gamma-synthase activity
NF392_RS11795	COG0646	methionine synthase
NF392_RS11795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NF392_RS11800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NF392_RS11810	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NF392_RS11815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NF392_RS11820	COG0183	Belongs to the thiolase family
NF392_RS11825	COG0346	lactoylglutathione lyase activity
NF392_RS11840	COG0583	DNA-binding transcription factor activity
NF392_RS11845	COG0281	malic enzyme
NF392_RS11855	COG0657	acetylesterase activity
NF392_RS11860	COG2271	Major facilitator Superfamily
NF392_RS11895	COG1136	(ABC) transporter
NF392_RS11900	COG0577	efflux transmembrane transporter activity
NF392_RS11930	COG0577	efflux transmembrane transporter activity
NF392_RS11935	COG1136	(ABC) transporter
NF392_RS11940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NF392_RS11970	COG0546	phosphoglycolate phosphatase activity
NF392_RS11975	COG0300	oxidoreductase activity
NF392_RS11980	COG1475	DNA binding
NF392_RS11985	COG0357	Ribosomal RNA small subunit methyltransferase G
NF392_RS11990	COG0445	tRNA wobble uridine modification
NF392_RS11995	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NF392_RS12000	COG0594	ribonuclease P activity
NF392_RS12050	COG0583	DNA-binding transcription factor activity