locus-tag	class	description
EL289_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EL289_RS00010	COG0592	DNA-directed DNA polymerase activity
EL289_RS00015	COG2501	S4 domain
EL289_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EL289_RS00025	COG0187	DNA topoisomerase II activity
EL289_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EL289_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EL289_RS00050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EL289_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EL289_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EL289_RS00075	COG0359	binds to the 23S rRNA
EL289_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
EL289_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EL289_RS00100	COG0745	RESPONSE REGULATOR receiver
EL289_RS00105	COG5002	protein histidine kinase activity
EL289_RS00110	COG4863	YycH protein
EL289_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EL289_RS00125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EL289_RS00145	COG3425	synthase
EL289_RS00155	COG0584	glycerophosphoryl diester phosphodiesterase
EL289_RS00160	COG2030	dehydratase
EL289_RS00280	COG3586	endonuclease activity
EL289_RS00305	COG1757	Na H antiporter
EL289_RS00315	COG1755	Isoprenylcysteine carboxyl methyltransferase
EL289_RS00320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EL289_RS00355	COG1136	(ABC) transporter
EL289_RS00360	COG1959	2 iron, 2 sulfur cluster binding
EL289_RS00365	COG2910	NAD(P)H-binding
EL289_RS00415	COG1129	ABC transporter
EL289_RS00430	COG1132	(ABC) transporter
EL289_RS00430	COG2375	cellular response to nickel ion
EL289_RS00435	COG1132	(ABC) transporter
EL289_RS00460	COG1021	2,3-dihydroxybenzoate-AMP ligase
EL289_RS00465	COG3433	isochorismatase activity
EL289_RS00465	COG2226	methyltransferase
EL289_RS00465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EL289_RS00480	COG0745	RESPONSE REGULATOR receiver
EL289_RS00485	COG2205	protein histidine kinase activity
EL289_RS00495	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EL289_RS00500	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EL289_RS00515	COG0747	negative chemotaxis
EL289_RS00520	COG0601	transmembrane transport
EL289_RS00530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EL289_RS00535	COG1124	(ABC) transporter
EL289_RS00580	COG0601	transmembrane transport
EL289_RS00590	COG0444	Belongs to the ABC transporter superfamily
EL289_RS00595	COG1124	(ABC) transporter
EL289_RS00620	COG1114	Component of the transport system for branched-chain amino acids
EL289_RS00630	COG1288	antiporter activity
EL289_RS00640	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EL289_RS00650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EL289_RS00675	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EL289_RS00680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EL289_RS00710	COG2814	Major facilitator Superfamily
EL289_RS00715	COG0583	DNA-binding transcription factor activity
EL289_RS00735	COG1131	(ABC) transporter
EL289_RS00745	COG2205	protein histidine kinase activity
EL289_RS00780	COG2814	Major facilitator Superfamily
EL289_RS00805	COG1012	belongs to the aldehyde dehydrogenase family
EL289_RS00810	COG2318	DinB family
EL289_RS00815	COG4221	oxidoreductase activity
EL289_RS00820	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EL289_RS00825	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EL289_RS00830	COG2962	Rard protein
EL289_RS00835	COG2409	Drug exporters of the RND superfamily
EL289_RS00835	COG1033	growth of symbiont in host cell
EL289_RS00850	COG0471	metal ion transport
EL289_RS00870	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EL289_RS00885	COG1054	Belongs to the UPF0176 family
EL289_RS00890	COG3386	PFAM SMP-30 Gluconolaconase
EL289_RS00900	COG2353	YceI-like domain
EL289_RS00910	COG0579	oxidoreductase
EL289_RS00920	COG1686	Belongs to the peptidase S11 family
EL289_RS00945	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EL289_RS00950	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EL289_RS00955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EL289_RS00960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EL289_RS00965	COG0131	Imidazoleglycerol-phosphate dehydratase
EL289_RS00970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EL289_RS00975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EL289_RS00980	COG0107	imidazoleglycerol-phosphate synthase activity
EL289_RS00985	COG0140	phosphoribosyl-ATP diphosphatase activity
EL289_RS00985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EL289_RS01010	COG0726	polysaccharide deacetylase
EL289_RS01020	COG1215	transferase activity, transferring glycosyl groups
EL289_RS01055	COG0456	acetyltransferase
EL289_RS01085	COG0737	Belongs to the 5'-nucleotidase family
EL289_RS01100	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EL289_RS01105	COG3639	organic phosphonate transmembrane transporter activity
EL289_RS01170	COG0604	alcohol dehydrogenase
EL289_RS01190	COG2409	Drug exporters of the RND superfamily
EL289_RS01200	COG0583	DNA-binding transcription factor activity
EL289_RS01205	COG3842	ATPase activity
EL289_RS01210	COG1840	ABC-type Fe3 transport system, periplasmic component
EL289_RS01220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EL289_RS01230	COG1764	response to oxidative stress
EL289_RS01265	COG3942	CHAP domain
EL289_RS01265	COG1705	Flagellar rod assembly protein muramidase FlgJ
EL289_RS01275	COG1482	cell wall glycoprotein biosynthetic process
EL289_RS01280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL289_RS01280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL289_RS01280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL289_RS01285	COG3711	transcriptional antiterminator
EL289_RS01285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL289_RS01295	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EL289_RS01415	COG2235	arginine
EL289_RS01435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EL289_RS01455	COG2843	Capsule synthesis protein
EL289_RS01475	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EL289_RS01480	COG3961	Belongs to the TPP enzyme family
EL289_RS01485	COG1846	Transcriptional regulator
EL289_RS01490	COG4195	phage-related replication protein
EL289_RS01495	COG4195	phage-related replication protein
EL289_RS01500	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EL289_RS01575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EL289_RS01580	COG0110	maltose O-acetyltransferase activity
EL289_RS01585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EL289_RS01590	COG1316	TRANSCRIPTIONal
EL289_RS01595	COG1785	Belongs to the alkaline phosphatase family
EL289_RS01605	COG2205	protein histidine kinase activity
EL289_RS01610	COG1136	(ABC) transporter
EL289_RS01625	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EL289_RS01650	COG1846	Transcriptional regulator
EL289_RS01660	COG0386	Belongs to the glutathione peroxidase family
EL289_RS01665	COG0175	sulfate reduction
EL289_RS01670	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EL289_RS01675	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EL289_RS01690	COG0730	response to heat
EL289_RS01695	COG2046	Belongs to the sulfate adenylyltransferase family
EL289_RS01700	COG0529	Catalyzes the synthesis of activated sulfate
EL289_RS01710	COG3942	CHAP domain
EL289_RS01720	COG1328	CTP reductase activity
EL289_RS01725	COG0602	queuosine metabolic process
EL289_RS01730	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EL289_RS01740	COG1510	regulation of RNA biosynthetic process
EL289_RS01745	COG1012	belongs to the aldehyde dehydrogenase family
EL289_RS01750	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EL289_RS01755	COG1473	amidohydrolase
EL289_RS01775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EL289_RS01780	COG0574	Belongs to the PEP-utilizing enzyme family
EL289_RS01780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EL289_RS01785	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EL289_RS01790	COG0579	oxidoreductase
EL289_RS01820	COG3588	fructose-bisphosphate aldolase
EL289_RS01835	COG0446	pyridine nucleotide-disulphide oxidoreductase
EL289_RS01870	COG0531	amino acid
EL289_RS01880	COG0583	DNA-binding transcription factor activity
EL289_RS01885	COG0039	L-malate dehydrogenase activity
EL289_RS01890	COG0028	Belongs to the TPP enzyme family
EL289_RS01895	COG3527	Alpha-acetolactate decarboxylase
EL289_RS01905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EL289_RS01910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EL289_RS01925	COG4640	response to antibiotic
EL289_RS01935	COG4640	response to antibiotic
EL289_RS01960	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EL289_RS01970	COG0167	dihydroorotate dehydrogenase activity
EL289_RS01975	COG3001	Fructosamine kinase
EL289_RS01990	COG0596	Alpha beta hydrolase
EL289_RS02035	COG1113	amino acid transport
EL289_RS02050	COG0741	lytic transglycosylase activity
EL289_RS02080	COG0436	Aminotransferase
EL289_RS02085	COG2608	mercury ion transmembrane transporter activity
EL289_RS02090	COG2217	Heavy metal translocating P-type atpase
EL289_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
EL289_RS02120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EL289_RS02125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EL289_RS02130	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EL289_RS02135	COG1012	belongs to the aldehyde dehydrogenase family
EL289_RS02170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EL289_RS02175	COG3425	synthase
EL289_RS02195	COG0583	DNA-binding transcription factor activity
EL289_RS02200	COG1380	Effector of murein hydrolase LrgA
EL289_RS02205	COG1346	cytolysis
EL289_RS02210	COG0028	Belongs to the TPP enzyme family
EL289_RS02215	COG2190	(PTS) system
EL289_RS02215	COG1263	PTS System
EL289_RS02215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL289_RS02235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL289_RS02240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EL289_RS02245	COG0657	acetylesterase activity
EL289_RS02250	COG0697	spore germination
EL289_RS02255	COG1917	Cupin 2, conserved barrel domain protein
EL289_RS02255	COG2207	Transcriptional regulator
EL289_RS02265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EL289_RS02275	COG2843	Capsule synthesis protein
EL289_RS02290	COG4975	Glucose uptake
EL289_RS02295	COG1869	D-ribose catabolic process
EL289_RS02305	COG1070	Carbohydrate kinase
EL289_RS02320	COG1760	l-serine dehydratase
EL289_RS02325	COG1760	l-serine dehydratase
EL289_RS02340	COG3764	Sortase (surface protein transpeptidase)
EL289_RS02345	COG0561	phosphatase activity
EL289_RS02350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EL289_RS02355	COG0778	Nitroreductase
EL289_RS02360	COG1012	belongs to the aldehyde dehydrogenase family
EL289_RS02365	COG2514	catechol 2,3-dioxygenase activity
EL289_RS02385	COG3949	Membrane
EL289_RS02395	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EL289_RS02400	COG0586	Pfam SNARE associated Golgi protein
EL289_RS02405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EL289_RS02410	COG2022	thiamine diphosphate biosynthetic process
EL289_RS02420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EL289_RS02430	COG2271	Major facilitator Superfamily
EL289_RS02445	COG4876	unkown
EL289_RS02450	COG2357	RelA SpoT domain protein
EL289_RS02465	COG1802	Transcriptional regulator
EL289_RS02470	COG1070	Carbohydrate kinase
EL289_RS02475	COG2610	gluconate transmembrane transporter activity
EL289_RS02480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EL289_RS02485	COG1216	Glycosyl transferase, family 2
EL289_RS02505	COG4221	oxidoreductase activity
EL289_RS02510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EL289_RS02515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EL289_RS02520	COG0248	Ppx GppA phosphatase
EL289_RS02525	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EL289_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
EL289_RS02540	COG1363	Peptidase, m42
EL289_RS02545	COG4808	Protein conserved in bacteria
EL289_RS02550	COG0069	glutamate synthase activity
EL289_RS02565	COG4619	ABC transporter
EL289_RS02570	COG0390	transport system, permease component
EL289_RS02575	COG2205	protein histidine kinase activity
EL289_RS02580	COG0745	RESPONSE REGULATOR receiver
EL289_RS02590	COG2814	Major facilitator Superfamily
EL289_RS02595	COG2272	Belongs to the type-B carboxylesterase lipase family
EL289_RS02600	COG0531	amino acid
EL289_RS02605	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EL289_RS02610	COG1063	alcohol dehydrogenase
EL289_RS02630	COG1174	glycine betaine transport
EL289_RS02635	COG1346	cytolysis
EL289_RS02640	COG1380	Effector of murein hydrolase LrgA
EL289_RS02650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EL289_RS02665	COG0706	membrane insertase activity
EL289_RS02675	COG0531	amino acid
EL289_RS02685	COG1113	amino acid transport
EL289_RS02705	COG2814	Major facilitator Superfamily
EL289_RS02715	COG1929	Belongs to the glycerate kinase type-1 family
EL289_RS02730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EL289_RS02735	COG0588	phosphoglycerate mutase activity
EL289_RS02745	COG2814	Major facilitator Superfamily
EL289_RS02750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL289_RS02755	COG0765	amino acid transport
EL289_RS02760	COG1126	abc transporter atp-binding protein
EL289_RS02770	COG2348	transferase activity, transferring amino-acyl groups
EL289_RS02800	COG2116	formate transmembrane transporter activity
EL289_RS02805	COG0454	-acetyltransferase
EL289_RS02810	COG0747	negative chemotaxis
EL289_RS02825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EL289_RS02830	COG2146	nitrite reductase [NAD(P)H] activity
EL289_RS02840	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EL289_RS02845	COG1140	nitrate reductase beta subunit
EL289_RS02855	COG2181	nitrate reductase activity
EL289_RS02865	COG4585	Histidine kinase
EL289_RS02870	COG2197	response regulator
EL289_RS02875	COG2223	nitrite transmembrane transporter activity
EL289_RS02885	COG1846	Transcriptional regulator
EL289_RS02890	COG0778	Nitroreductase
EL289_RS02940	COG1028	Short-chain dehydrogenase reductase Sdr
EL289_RS02950	COG0534	Mate efflux family protein
EL289_RS02970	COG0492	ferredoxin-NADP+ reductase activity
EL289_RS02980	COG0604	alcohol dehydrogenase
EL289_RS02985	COG2822	iron ion transport
EL289_RS02995	COG0672	)-iron permease
EL289_RS03000	COG0805	protein transport
EL289_RS03005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EL289_RS03015	COG0463	Glycosyl transferase, family 2
EL289_RS03015	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EL289_RS03025	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EL289_RS03025	COG0463	Glycosyl transferase, family 2
EL289_RS03030	COG1620	l-lactate permease
EL289_RS03040	COG0579	oxidoreductase
EL289_RS03045	COG3850	Histidine kinase
EL289_RS03045	COG5002	protein histidine kinase activity
EL289_RS03050	COG0745	RESPONSE REGULATOR receiver
EL289_RS03055	COG0577	efflux transmembrane transporter activity
EL289_RS03060	COG1136	(ABC) transporter
EL289_RS03075	COG4640	response to antibiotic
EL289_RS03080	COG2814	Major facilitator Superfamily
EL289_RS03090	COG1566	PFAM secretion protein HlyD family protein
EL289_RS03095	COG2814	Major facilitator Superfamily
EL289_RS03120	COG0598	Magnesium transport protein CorA
EL289_RS03125	COG1304	FMN binding
EL289_RS03130	COG0786	glutamate:sodium symporter activity
EL289_RS03135	COG2094	Belongs to the DNA glycosylase MPG family
EL289_RS03140	COG3152	Membrane
EL289_RS03155	COG1069	ribulokinase activity
EL289_RS03160	COG4152	abc transporter atp-binding protein
EL289_RS03165	COG1668	transmembrane transport
EL289_RS03170	COG1742	UPF0060 membrane protein
EL289_RS03175	COG2017	converts alpha-aldose to the beta-anomer
EL289_RS03180	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EL289_RS03185	COG1266	CAAX protease self-immunity
EL289_RS03190	COG0010	Belongs to the arginase family
EL289_RS03210	COG1473	amidohydrolase
EL289_RS03215	COG1028	Short-chain dehydrogenase reductase Sdr
EL289_RS03235	COG1737	Transcriptional regulator
EL289_RS03240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL289_RS03240	COG1263	PTS System
EL289_RS03250	COG0385	Bile acid
EL289_RS03255	COG0546	phosphoglycolate phosphatase activity
EL289_RS03275	COG1113	amino acid transport
EL289_RS03285	COG1263	PTS System
EL289_RS03285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL289_RS03290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EL289_RS03310	COG2378	regulation of single-species biofilm formation
EL289_RS03320	COG1316	TRANSCRIPTIONal
EL289_RS03350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EL289_RS03355	COG2076	Multidrug Resistance protein
EL289_RS03360	COG2076	Multidrug Resistance protein
EL289_RS03365	COG3942	CHAP domain
EL289_RS03380	COG1757	Na H antiporter
EL289_RS03385	COG3942	CHAP domain
EL289_RS03395	COG1846	Transcriptional regulator
EL289_RS03410	COG0829	nickel cation binding
EL289_RS03420	COG0830	nickel cation binding
EL289_RS03425	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EL289_RS03430	COG0804	urea catabolic process
EL289_RS03435	COG0832	Belongs to the urease beta subunit family
EL289_RS03440	COG0831	urea catabolic process
EL289_RS03445	COG4413	Urea transporter
EL289_RS03450	COG1960	acyl-CoA dehydrogenase activity
EL289_RS03455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EL289_RS03465	COG1268	BioY protein
EL289_RS03475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EL289_RS03480	COG0725	ABC transporter, periplasmic molybdate-binding protein
EL289_RS03485	COG4149	molybdate abc transporter
EL289_RS03490	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EL289_RS03495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EL289_RS03500	COG0521	Mo-molybdopterin cofactor biosynthetic process
EL289_RS03505	COG0315	cyclic pyranopterin monophosphate synthase activity
EL289_RS03510	COG0303	'Molybdopterin
EL289_RS03530	COG0746	molybdenum cofactor guanylyltransferase activity
EL289_RS03535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EL289_RS03545	COG2814	Major facilitator Superfamily
EL289_RS03565	COG2348	transferase activity, transferring amino-acyl groups
EL289_RS03570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EL289_RS03590	COG4975	Glucose uptake
EL289_RS03600	COG0551	DNA topoisomerase type I activity
EL289_RS03600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EL289_RS03605	COG2252	PERMEase
EL289_RS03620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EL289_RS03625	COG0088	Forms part of the polypeptide exit tunnel
EL289_RS03630	COG0089	rRNA binding
EL289_RS03635	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EL289_RS03640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EL289_RS03655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EL289_RS03665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EL289_RS03670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EL289_RS03675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EL289_RS03680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EL289_RS03685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EL289_RS03690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EL289_RS03695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EL289_RS03700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EL289_RS03705	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EL289_RS03710	COG1841	ribosomal large subunit assembly
EL289_RS03715	COG0200	Binds to the 23S rRNA
EL289_RS03720	COG0201	protein transport
EL289_RS03725	COG0563	adenylate kinase activity
EL289_RS03730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EL289_RS03735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EL289_RS03740	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EL289_RS03750	COG0202	RNA polymerase activity
EL289_RS03755	COG0203	ribosomal protein L17
EL289_RS03760	COG1122	ATPase activity
EL289_RS03765	COG1122	ATPase activity
EL289_RS03775	COG0101	tRNA pseudouridine synthase activity
EL289_RS03780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EL289_RS03790	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EL289_RS03795	COG1349	DNA-binding transcription factor activity
EL289_RS03800	COG0698	ribose 5-phosphate isomerase
EL289_RS03825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL289_RS03825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL289_RS03830	COG2723	6-phospho-beta-galactosidase activity
EL289_RS03840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EL289_RS03845	COG2130	NADP-dependent
EL289_RS03850	COG0604	alcohol dehydrogenase
EL289_RS03865	COG1302	Protein conserved in bacteria
EL289_RS03870	COG4264	IucA IucC family
EL289_RS03875	COG2814	Major facilitator Superfamily
EL289_RS03880	COG4264	IucA IucC family
EL289_RS03885	COG3457	Alanine racemase
EL289_RS03890	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EL289_RS03895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL289_RS03900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL289_RS03905	COG3314	Sporulation integral membrane protein YlbJ
EL289_RS03910	COG2329	Antibiotic biosynthesis monooxygenase
EL289_RS03920	COG1988	membrane-bound metal-dependent
EL289_RS03925	COG4284	Utp--glucose-1-phosphate uridylyltransferase
EL289_RS03945	COG2814	Major facilitator Superfamily
EL289_RS03950	COG0489	protein tyrosine kinase activity
EL289_RS04005	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EL289_RS04015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EL289_RS04030	COG3711	transcriptional antiterminator
EL289_RS04040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EL289_RS04045	COG0561	phosphatase activity
EL289_RS04065	COG0640	Transcriptional regulator
EL289_RS04070	COG0702	epimerase
EL289_RS04075	COG1482	cell wall glycoprotein biosynthetic process
EL289_RS04095	COG0783	Belongs to the Dps family
EL289_RS04100	COG0813	purine-nucleoside phosphorylase activity
EL289_RS04105	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EL289_RS04110	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EL289_RS04115	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EL289_RS04125	COG1854	S-ribosylhomocysteine lyase activity
EL289_RS04145	COG5146	pantothenate kinase activity
EL289_RS04150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EL289_RS04155	COG3343	RNA polymerase activity
EL289_RS04160	COG0504	CTP synthase activity
EL289_RS04175	COG0191	fructose-bisphosphate aldolase activity
EL289_RS04180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EL289_RS04190	COG1012	belongs to the aldehyde dehydrogenase family
EL289_RS04195	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EL289_RS04200	COG0254	rRNA binding
EL289_RS04205	COG1435	thymidine kinase activity
EL289_RS04215	COG2890	protein-(glutamine-N5) methyltransferase activity
EL289_RS04220	COG0009	L-threonylcarbamoyladenylate synthase
EL289_RS04225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EL289_RS04230	COG4475	Protein of unknown function (DUF436)
EL289_RS04235	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EL289_RS04240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EL289_RS04245	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EL289_RS04255	COG0356	it plays a direct role in the translocation of protons across the membrane
EL289_RS04265	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EL289_RS04270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EL289_RS04275	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EL289_RS04280	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EL289_RS04285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EL289_RS04290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EL289_RS04305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EL289_RS04315	COG0629	single-stranded DNA binding
EL289_RS04320	COG1388	LysM domain
EL289_RS04325	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EL289_RS04335	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EL289_RS04340	COG0352	thiamine-phosphate diphosphorylase activity
EL289_RS04345	COG0706	membrane insertase activity
EL289_RS04350	COG1418	mRNA catabolic process
EL289_RS04355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EL289_RS04360	COG1937	Protein conserved in bacteria
EL289_RS04375	COG0772	Belongs to the SEDS family
EL289_RS04380	COG1181	Belongs to the D-alanine--D-alanine ligase family
EL289_RS04385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EL289_RS04390	COG0513	Belongs to the DEAD box helicase family
EL289_RS04405	COG3402	PFAM membrane-flanked domain
EL289_RS04410	COG0736	holo-[acyl-carrier-protein] synthase activity
EL289_RS04415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EL289_RS04425	COG2337	Toxic component of a toxin-antitoxin (TA) module
EL289_RS04430	COG2208	phosphoserine phosphatase activity
EL289_RS04445	COG1191	sigma factor activity
EL289_RS04450	COG2183	response to ionizing radiation
EL289_RS04455	COG3091	SprT-like family
EL289_RS04495	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EL289_RS04500	COG0473	3-isopropylmalate dehydrogenase activity
EL289_RS04505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EL289_RS04510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EL289_RS04520	COG0028	Belongs to the TPP enzyme family
EL289_RS04525	COG0129	dihydroxy-acid dehydratase activity
EL289_RS04530	COG0802	atpase or kinase
EL289_RS04535	COG1214	PFAM Peptidase M22, glycoprotease
EL289_RS04540	COG0456	acetyltransferase
EL289_RS04545	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EL289_RS04550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EL289_RS04555	COG0488	(ABC) transporter
EL289_RS04560	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EL289_RS04570	COG2391	methyltransferase activity
EL289_RS04575	COG0425	Belongs to the sulfur carrier protein TusA family
EL289_RS04580	COG0004	ammonium transporteR
EL289_RS04585	COG1621	beta-fructofuranosidase activity
EL289_RS04590	COG3279	Response regulator of the LytR AlgR family
EL289_RS04635	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EL289_RS04640	COG0459	protein refolding
EL289_RS04645	COG0582	viral genome integration into host DNA
EL289_RS04740	COG3682	Transcriptional regulator
EL289_RS04780	COG1725	Transcriptional regulator
EL289_RS04795	COG1131	(ABC) transporter
EL289_RS04845	COG4974	Belongs to the 'phage' integrase family
EL289_RS04875	COG3682	Transcriptional regulator
EL289_RS04885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EL289_RS04890	COG2706	6-phosphogluconolactonase activity
EL289_RS04895	COG1012	belongs to the aldehyde dehydrogenase family
EL289_RS04900	COG1227	inorganic diphosphatase activity
EL289_RS04905	COG1335	isochorismatase
EL289_RS04915	COG0077	Prephenate dehydratase
EL289_RS04925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EL289_RS04930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EL289_RS04935	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EL289_RS04950	COG4496	protein, YerC YecD
EL289_RS04955	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EL289_RS04960	COG0210	DNA helicase
EL289_RS04965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EL289_RS04975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EL289_RS04980	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EL289_RS04985	COG0154	amidase activity
EL289_RS04990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EL289_RS04995	COG1597	lipid kinase activity
EL289_RS05000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EL289_RS05020	COG1528	Iron-storage protein
EL289_RS05040	COG4129	membrane
EL289_RS05045	COG0024	Methionine aminopeptidase
EL289_RS05065	COG2197	response regulator
EL289_RS05070	COG1295	ribonuclease BN
EL289_RS05080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EL289_RS05085	COG4840	Belongs to the UPF0435 family
EL289_RS05090	COG2309	aminopeptidase activity
EL289_RS05095	COG1607	acyl-coa hydrolase
EL289_RS05100	COG0535	radical SAM domain protein
EL289_RS05110	COG0693	protein deglycase activity
EL289_RS05115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EL289_RS05120	COG2137	regulation of response to DNA damage stimulus
EL289_RS05130	COG1388	LysM domain
EL289_RS05130	COG1134	teichoic acid transport
EL289_RS05140	COG1988	membrane-bound metal-dependent
EL289_RS05150	COG3557	Belongs to the UPF0374 family
EL289_RS05160	COG4129	membrane
EL289_RS05165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EL289_RS05170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EL289_RS05175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EL289_RS05180	COG0735	belongs to the Fur family
EL289_RS05355	COG0765	amino acid transport
EL289_RS05360	COG1126	abc transporter atp-binding protein
EL289_RS05365	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EL289_RS05375	COG0363	glucosamine-6-phosphate deaminase activity
EL289_RS05390	COG0114	fumarate hydratase activity
EL289_RS05395	COG0564	pseudouridine synthase activity
EL289_RS05400	COG2203	Gaf domain
EL289_RS05400	COG4585	Histidine kinase
EL289_RS05405	COG2197	response regulator
EL289_RS05415	COG4399	Belongs to the UPF0754 family
EL289_RS05420	COG3679	Belongs to the UPF0342 family
EL289_RS05425	COG0420	3'-5' exonuclease activity
EL289_RS05435	COG3481	metal-dependent phosphohydrolase, HD sub domain
EL289_RS05445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EL289_RS05460	COG0537	adenosine 5'-monophosphoramidase activity
EL289_RS05465	COG1131	(ABC) transporter
EL289_RS05470	COG4473	ABC transporter
EL289_RS05475	COG2329	Antibiotic biosynthesis monooxygenase
EL289_RS05480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EL289_RS05485	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EL289_RS05490	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EL289_RS05495	COG3545	Serine hydrolase
EL289_RS05545	COG0318	PFAM AMP-dependent synthetase and ligase
EL289_RS05560	COG0494	nUDIX hydrolase
EL289_RS05565	COG1506	peptidase
EL289_RS05575	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EL289_RS05585	COG0656	L-ascorbic acid biosynthetic process
EL289_RS05590	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EL289_RS05595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EL289_RS05605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EL289_RS05630	COG3266	domain, Protein
EL289_RS05630	COG4193	domain, Protein
EL289_RS05630	COG5632	N-Acetylmuramoyl-L-alanine amidase
EL289_RS05640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EL289_RS05640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EL289_RS05650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EL289_RS05650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EL289_RS05655	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EL289_RS05660	COG0506	proline dehydrogenase activity
EL289_RS05665	COG2267	carboxylic ester hydrolase activity
EL289_RS05675	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EL289_RS05680	COG1242	4 iron, 4 sulfur cluster binding
EL289_RS05685	COG2814	Major facilitator Superfamily
EL289_RS05690	COG0495	leucyl-tRNA aminoacylation
EL289_RS05705	COG2081	HI0933 family
EL289_RS05710	COG2244	polysaccharide biosynthetic process
EL289_RS05715	COG1187	pseudouridine synthase activity
EL289_RS05725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EL289_RS05730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EL289_RS05735	COG0510	thiamine kinase activity
EL289_RS05740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EL289_RS05745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EL289_RS05755	COG1363	Peptidase, m42
EL289_RS05760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL289_RS05765	COG4848	Belongs to the UPF0354 family
EL289_RS05770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL289_RS05775	COG1674	ftsk spoiiie
EL289_RS05780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EL289_RS05785	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EL289_RS05795	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EL289_RS05795	COG1605	Chorismate mutase
EL289_RS05800	COG1609	Transcriptional regulator
EL289_RS05810	COG0454	-acetyltransferase
EL289_RS05815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EL289_RS05820	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EL289_RS05830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EL289_RS05840	COG0477	Major facilitator Superfamily
EL289_RS05845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EL289_RS05850	COG0204	Acyl-transferase
EL289_RS05855	COG1263	PTS System
EL289_RS05855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL289_RS05865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EL289_RS05875	COG1764	response to oxidative stress
EL289_RS05880	COG0584	glycerophosphoryl diester phosphodiesterase
EL289_RS05885	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EL289_RS05895	COG1956	GAF domain-containing protein
EL289_RS05900	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EL289_RS05905	COG1104	cysteine desulfurase activity
EL289_RS05910	COG0301	tRNA thio-modification
EL289_RS05920	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EL289_RS05925	COG0827	DNA restriction-modification system
EL289_RS05930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EL289_RS05935	COG0589	response to stress
EL289_RS05945	COG0006	proline dipeptidase activity
EL289_RS05950	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EL289_RS05960	COG4109	DRTGG domain
EL289_RS05965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EL289_RS05970	COG0587	DNA-directed DNA polymerase activity
EL289_RS05975	COG0281	malic enzyme
EL289_RS05980	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EL289_RS05990	COG0205	6-phosphofructokinase activity
EL289_RS05995	COG0469	pyruvate kinase activity
EL289_RS06000	COG1113	amino acid transport
EL289_RS06005	COG0372	Belongs to the citrate synthase family
EL289_RS06010	COG0538	isocitrate dehydrogenase activity
EL289_RS06015	COG0745	RESPONSE REGULATOR receiver
EL289_RS06020	COG5002	protein histidine kinase activity
EL289_RS06025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL289_RS06025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL289_RS06030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EL289_RS06035	COG0237	dephospho-CoA kinase activity
EL289_RS06040	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EL289_RS06045	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EL289_RS06050	COG3611	Membrane attachment protein
EL289_RS06055	COG1484	DNA-dependent DNA replication
EL289_RS06060	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EL289_RS06065	COG0833	amino acid
EL289_RS06070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EL289_RS06075	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EL289_RS06080	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EL289_RS06085	COG4112	unkown
EL289_RS06095	COG0544	peptidyl-prolyl cis-trans isomerase activity
EL289_RS06100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EL289_RS06105	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EL289_RS06110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EL289_RS06115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EL289_RS06120	COG0181	hydroxymethylbilane synthase activity
EL289_RS06130	COG0113	porphobilinogen synthase activity
EL289_RS06135	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EL289_RS06145	COG2818	Glycosylase
EL289_RS06150	COG0525	valine-tRNA ligase activity
EL289_RS06155	COG0285	dihydrofolate synthase activity
EL289_RS06165	COG2003	Belongs to the UPF0758 family
EL289_RS06205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EL289_RS06235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EL289_RS06240	COG2868	ribosomal protein
EL289_RS06245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EL289_RS06250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EL289_RS06255	COG4492	Belongs to the UPF0735 family
EL289_RS06260	COG0632	four-way junction helicase activity
EL289_RS06265	COG2255	four-way junction helicase activity
EL289_RS06275	COG0343	queuine tRNA-ribosyltransferase activity
EL289_RS06280	COG1862	Preprotein translocase
EL289_RS06285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EL289_RS06285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EL289_RS06290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EL289_RS06290	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EL289_RS06300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EL289_RS06305	COG1490	D-aminoacyl-tRNA deacylase activity
EL289_RS06310	COG0860	N-Acetylmuramoyl-L-alanine amidase
EL289_RS06320	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EL289_RS06330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EL289_RS06335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EL289_RS06340	COG1959	2 iron, 2 sulfur cluster binding
EL289_RS06355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EL289_RS06360	COG1104	cysteine desulfurase activity
EL289_RS06365	COG0482	sulfurtransferase activity
EL289_RS06375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EL289_RS06380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EL289_RS06385	COG4472	Bacterial protein of unknown function (DUF965)
EL289_RS06390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EL289_RS06395	COG3906	Belongs to the UPF0473 family
EL289_RS06405	COG0826	peptidase U32
EL289_RS06410	COG0826	peptidase U32
EL289_RS06415	COG0572	uridine kinase
EL289_RS06420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EL289_RS06425	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EL289_RS06430	COG1984	allophanate hydrolase subunit 2
EL289_RS06435	COG0511	ligase activity, forming carbon-carbon bonds
EL289_RS06440	COG0439	Biotin carboxylase
EL289_RS06445	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EL289_RS06450	COG1914	H( )-stimulated, divalent metal cation uptake system
EL289_RS06455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EL289_RS06460	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EL289_RS06465	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EL289_RS06475	COG1534	Rna-binding protein
EL289_RS06480	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EL289_RS06485	COG1713	HD superfamily hydrolase involved in NAD metabolism
EL289_RS06490	COG0799	negative regulation of ribosome biogenesis
EL289_RS06495	COG4106	trans-aconitate 2-methyltransferase activity
EL289_RS06500	COG1596	polysaccharide export
EL289_RS06500	COG1555	photosystem II stabilization
EL289_RS06505	COG2131	deaminase
EL289_RS06510	COG0658	competence protein
EL289_RS06510	COG2333	competence protein COMEC
EL289_RS06515	COG1466	dna polymerase III delta subunit
EL289_RS06520	COG0268	Binds directly to 16S ribosomal RNA
EL289_RS06525	COG0481	GTPase activity
EL289_RS06530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EL289_RS06535	COG1420	regulation of RNA biosynthetic process
EL289_RS06540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EL289_RS06545	COG0443	Heat shock 70 kDa protein
EL289_RS06550	COG0484	heat shock protein binding
EL289_RS06555	COG2264	protein methyltransferase activity
EL289_RS06560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EL289_RS06565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EL289_RS06575	COG1030	water channel activity
EL289_RS06580	COG4864	UPF0365 protein
EL289_RS06590	COG1702	phosphate starvation-inducible protein PhoH
EL289_RS06595	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EL289_RS06610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EL289_RS06615	COG1381	Involved in DNA repair and RecF pathway recombination
EL289_RS06620	COG0423	glycine-tRNA ligase activity
EL289_RS06625	COG0517	IMP dehydrogenase activity
EL289_RS06630	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EL289_RS06635	COG0358	DNA primase activity
EL289_RS06640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EL289_RS06645	COG2384	SAM-dependent methyltransferase
EL289_RS06650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EL289_RS06655	COG0513	Belongs to the DEAD box helicase family
EL289_RS06660	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EL289_RS06665	COG1121	(ABC) transporter
EL289_RS06670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EL289_RS06685	COG0768	penicillin binding
EL289_RS06690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EL289_RS06695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EL289_RS06700	COG0457	Tetratricopeptide repeat
EL289_RS06700	COG0705	Rhomboid family
EL289_RS06705	COG4483	Protein conserved in bacteria
EL289_RS06710	COG1940	carbohydrate kinase activity
EL289_RS06715	COG0011	TIGRFAM Protein of
EL289_RS06720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EL289_RS06725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EL289_RS06730	COG1459	type II secretion system
EL289_RS06735	COG4537	Required for transformation and DNA binding
EL289_RS06760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EL289_RS06765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EL289_RS06770	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EL289_RS06775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EL289_RS06780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL289_RS06785	COG0095	Lipoate-protein ligase
EL289_RS06800	COG0006	proline dipeptidase activity
EL289_RS06805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EL289_RS06810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EL289_RS06815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EL289_RS06820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EL289_RS06825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EL289_RS06830	COG0511	ligase activity, forming carbon-carbon bonds
EL289_RS06835	COG0439	Biotin carboxylase
EL289_RS06840	COG1302	Protein conserved in bacteria
EL289_RS06845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EL289_RS06850	COG1570	exodeoxyribonuclease VII activity
EL289_RS06860	COG0142	geranyltranstransferase activity
EL289_RS06865	COG1438	arginine binding
EL289_RS06870	COG0497	DNA recombination
EL289_RS06875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EL289_RS06880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EL289_RS06885	COG0022	dehydrogenase e1 component
EL289_RS06890	COG0508	dehydrogenase complex catalyzes the overall conversion of
EL289_RS06900	COG4129	membrane
EL289_RS06905	COG2195	Cleaves the N-terminal amino acid of tripeptides
EL289_RS06910	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EL289_RS06920	COG0366	Alpha amylase catalytic
EL289_RS06930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EL289_RS06935	COG1234	tRNA 3'-trailer cleavage
EL289_RS06940	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EL289_RS06945	COG0300	oxidoreductase activity
EL289_RS06950	COG0667	Aldo Keto reductase
EL289_RS06955	COG0494	nUDIX hydrolase
EL289_RS06960	COG0735	belongs to the Fur family
EL289_RS06965	COG4974	Belongs to the 'phage' integrase family
EL289_RS06975	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EL289_RS06980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EL289_RS06985	COG1187	pseudouridine synthase activity
EL289_RS06990	COG0745	RESPONSE REGULATOR receiver
EL289_RS07005	COG1141	Ferredoxin
EL289_RS07015	COG0514	ATP-dependent DNA helicase (RecQ)
EL289_RS07020	COG1388	LysM domain
EL289_RS07020	COG1388	LysM domain
EL289_RS07025	COG0492	ferredoxin-NADP+ reductase activity
EL289_RS07030	COG0252	asparaginase activity
EL289_RS07035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EL289_RS07040	COG0539	negative regulation of cytoplasmic translation
EL289_RS07045	COG1160	GTP binding
EL289_RS07050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EL289_RS07065	COG2226	methyltransferase
EL289_RS07075	COG0105	UTP biosynthetic process
EL289_RS07080	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EL289_RS07085	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EL289_RS07090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EL289_RS07100	COG5582	Belongs to the UPF0302 family
EL289_RS07105	COG4347	Protein of unknown function (DUF1405)
EL289_RS07110	COG2738	Putative neutral zinc metallopeptidase
EL289_RS07115	COG1694	Mazg nucleotide pyrophosphohydrolase
EL289_RS07120	COG0438	transferase activity, transferring glycosyl groups
EL289_RS07125	COG0617	tRNA 3'-terminal CCA addition
EL289_RS07130	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EL289_RS07130	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EL289_RS07135	COG1199	ATP-dependent helicase activity
EL289_RS07135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EL289_RS07140	COG0017	Asparaginyl-tRNA synthetase
EL289_RS07145	COG3935	DnaD domain protein
EL289_RS07150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EL289_RS07160	COG4499	WXG100 protein secretion system (Wss), protein YukC
EL289_RS07160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EL289_RS07165	COG3331	DNA recombination
EL289_RS07175	COG4474	Belongs to the UPF0398 family
EL289_RS07180	COG3599	regulation of cell shape
EL289_RS07190	COG0116	Belongs to the methyltransferase superfamily
EL289_RS07200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EL289_RS07205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL289_RS07210	COG1511	domain protein
EL289_RS07210	COG4372	Transposase
EL289_RS07210	COG1196	nuclear chromosome segregation
EL289_RS07220	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EL289_RS07230	COG1413	lyase activity
EL289_RS07235	COG1413	lyase activity
EL289_RS07265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL289_RS07270	COG2190	(PTS) system
EL289_RS07275	COG4479	Belongs to the UPF0346 family
EL289_RS07280	COG0793	Belongs to the peptidase S41A family
EL289_RS07290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EL289_RS07295	COG0671	phosphoesterase, PA-phosphatase related
EL289_RS07300	COG3842	ATPase activity
EL289_RS07305	COG4209	transmembrane transport
EL289_RS07315	COG0395	ABC-type sugar transport system, permease component
EL289_RS07325	COG0534	Mate efflux family protein
EL289_RS07330	COG1349	DNA-binding transcription factor activity
EL289_RS07335	COG0745	RESPONSE REGULATOR receiver
EL289_RS07340	COG5002	protein histidine kinase activity
EL289_RS07345	COG0567	Dehydrogenase, E1 component
EL289_RS07355	COG3177	Filamentation induced by cAMP protein fic
EL289_RS07360	COG1131	(ABC) transporter
EL289_RS07385	COG0714	Associated with various cellular activities
EL289_RS07390	COG4548	von Willebrand factor, type A
EL289_RS07395	COG1114	Component of the transport system for branched-chain amino acids
EL289_RS07400	COG3853	Toxic anion resistance protein (TelA)
EL289_RS07410	COG1254	Belongs to the acylphosphatase family
EL289_RS07420	COG1278	Cold shock
EL289_RS07435	COG1473	amidohydrolase
EL289_RS07440	COG2171	N-acyltransferase activity
EL289_RS07445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EL289_RS07450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EL289_RS07455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EL289_RS07460	COG0527	aspartate kinase activity
EL289_RS07465	COG0488	(ABC) transporter
EL289_RS07470	COG2996	Protein conserved in bacteria
EL289_RS07490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EL289_RS07495	COG0573	inorganic phosphate transmembrane transporter activity
EL289_RS07500	COG0581	inorganic phosphate transmembrane transporter activity
EL289_RS07505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EL289_RS07510	COG0704	Plays a role in the regulation of phosphate uptake
EL289_RS07515	COG1164	Oligoendopeptidase f
EL289_RS07550	COG2348	transferase activity, transferring amino-acyl groups
EL289_RS07555	COG2348	transferase activity, transferring amino-acyl groups
EL289_RS07565	COG0159	tryptophan synthase activity
EL289_RS07570	COG0133	tryptophan synthase activity
EL289_RS07575	COG0135	phosphoribosylanthranilate isomerase activity
EL289_RS07580	COG0134	indole-3-glycerol-phosphate synthase activity
EL289_RS07585	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EL289_RS07590	COG0512	Glutamine amidotransferase of anthranilate synthase
EL289_RS07595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EL289_RS07600	COG1363	Peptidase, m42
EL289_RS07605	COG0287	Prephenate dehydrogenase
EL289_RS07610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EL289_RS07615	COG1942	4-Oxalocrotonate Tautomerase
EL289_RS07630	COG0392	lysyltransferase activity
EL289_RS07630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EL289_RS07635	COG0628	permease
EL289_RS07640	COG3711	transcriptional antiterminator
EL289_RS07645	COG1115	amino acid carrier protein
EL289_RS07650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EL289_RS07655	COG0187	DNA topoisomerase II activity
EL289_RS07660	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EL289_RS07670	COG0824	Thioesterase
EL289_RS07675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EL289_RS07680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EL289_RS07685	COG1970	mechanosensitive ion channel activity
EL289_RS07690	COG0419	ATPase involved in DNA repair
EL289_RS07695	COG0420	3'-5' exonuclease activity
EL289_RS07700	COG4846	Membrane protein involved in cytochrome C biogenesis
EL289_RS07710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EL289_RS07715	COG4224	UPF0291 protein
EL289_RS07725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EL289_RS07730	COG2340	Cysteine-rich secretory protein family
EL289_RS07735	COG0516	GMP reductase activity
EL289_RS07740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EL289_RS07755	COG0833	amino acid
EL289_RS07770	COG0083	homoserine kinase activity
EL289_RS07775	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EL289_RS07780	COG0460	homoserine dehydrogenase
EL289_RS07785	COG0527	aspartate kinase activity
EL289_RS07800	COG1525	nuclease
EL289_RS07815	COG2197	response regulator
EL289_RS07820	COG4585	Histidine kinase
EL289_RS07830	COG1131	(ABC) transporter
EL289_RS07835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EL289_RS07890	COG0174	glutamine synthetase
EL289_RS07895	COG0789	Transcriptional regulator
EL289_RS07900	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EL289_RS07905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EL289_RS07910	COG0386	Belongs to the glutathione peroxidase family
EL289_RS07915	COG1923	regulation of RNA biosynthetic process
EL289_RS07920	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EL289_RS07930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EL289_RS07935	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EL289_RS07940	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EL289_RS07945	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EL289_RS07950	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EL289_RS07955	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EL289_RS07965	COG4550	Control of competence regulator ComK, YlbF/YmcA
EL289_RS07970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EL289_RS07980	COG4195	phage-related replication protein
EL289_RS07985	COG1013	pyruvate-flavodoxin oxidoreductase activity
EL289_RS07990	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EL289_RS07990	COG0674	pyruvate-flavodoxin oxidoreductase activity
EL289_RS07995	COG1692	metallophosphoesterase
EL289_RS08005	COG1418	mRNA catabolic process
EL289_RS08010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EL289_RS08015	COG1058	Belongs to the CinA family
EL289_RS08015	COG1546	Belongs to the CinA family
EL289_RS08020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EL289_RS08035	COG0300	oxidoreductase activity
EL289_RS08040	COG0612	Peptidase, M16
EL289_RS08045	COG0612	Peptidase, M16
EL289_RS08050	COG2188	Transcriptional regulator
EL289_RS08055	COG1674	ftsk spoiiie
EL289_RS08060	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EL289_RS08070	COG1185	polyribonucleotide nucleotidyltransferase activity
EL289_RS08075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EL289_RS08080	COG0196	riboflavin kinase activity
EL289_RS08085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EL289_RS08090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EL289_RS08095	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EL289_RS08105	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EL289_RS08110	COG0195	Participates in both transcription termination and antitermination
EL289_RS08115	COG0779	Required for maturation of 30S ribosomal subunits
EL289_RS08120	COG2176	DNA-directed DNA polymerase activity
EL289_RS08125	COG0442	prolyl-tRNA aminoacylation
EL289_RS08135	COG4589	Belongs to the CDS family
EL289_RS08140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EL289_RS08145	COG0233	cytoplasmic translational termination
EL289_RS08150	COG0528	UMP kinase activity
EL289_RS08155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EL289_RS08160	COG0052	Belongs to the universal ribosomal protein uS2 family
EL289_RS08175	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EL289_RS08180	COG4974	Belongs to the 'phage' integrase family
EL289_RS08185	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EL289_RS08190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EL289_RS08195	COG0758	DNA mediated transformation
EL289_RS08200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EL289_RS08205	COG0045	succinate-CoA ligase (ADP-forming) activity
EL289_RS08210	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EL289_RS08220	COG4485	Bacterial membrane protein, YfhO
EL289_RS08230	COG0335	large ribosomal subunit rRNA binding
EL289_RS08235	COG0336	Belongs to the RNA methyltransferase TrmD family
EL289_RS08240	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EL289_RS08245	COG0228	four-way junction DNA binding
EL289_RS08250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EL289_RS08255	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EL289_RS08260	COG0552	protein localization to endoplasmic reticulum
EL289_RS08265	COG1196	nuclear chromosome segregation
EL289_RS08270	COG0571	ribonuclease III activity
EL289_RS08275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EL289_RS08290	COG0416	fatty acid biosynthetic process
EL289_RS08295	COG1349	DNA-binding transcription factor activity
EL289_RS08300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EL289_RS08315	COG1461	Dihydroxyacetone kinase
EL289_RS08320	COG1302	Protein conserved in bacteria
EL289_RS08325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EL289_RS08330	COG1564	THIamine pyrophosphokinase
EL289_RS08335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EL289_RS08340	COG1162	GTPase activity
EL289_RS08345	COG2807	transmembrane transport
EL289_RS08355	COG0631	protein serine/threonine phosphatase activity
EL289_RS08360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EL289_RS08365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EL289_RS08365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EL289_RS08370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EL289_RS08375	COG0242	peptide deformylase activity
EL289_RS08390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EL289_RS08395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EL289_RS08400	COG1758	RNA polymerase activity
EL289_RS08405	COG0194	GDP metabolic process
EL289_RS08410	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EL289_RS08425	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EL289_RS08430	COG0284	orotidine-5'-phosphate decarboxylase activity
EL289_RS08435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EL289_RS08440	COG0505	Belongs to the CarA family
EL289_RS08445	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EL289_RS08450	COG0540	Belongs to the ATCase OTCase family
EL289_RS08455	COG2233	PERMEase
EL289_RS08460	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EL289_RS08465	COG0564	pseudouridine synthase activity
EL289_RS08470	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EL289_RS08485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EL289_RS08490	COG3599	regulation of cell shape
EL289_RS08500	COG0762	integral membrane protein
EL289_RS08505	COG1799	cell septum assembly
EL289_RS08510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EL289_RS08515	COG1496	oxidoreductase activity
EL289_RS08520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EL289_RS08525	COG0849	cell division
EL289_RS08530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EL289_RS08535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EL289_RS08540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EL289_RS08545	COG0768	penicillin binding
EL289_RS08550	COG4839	cell division protein FtsL
EL289_RS08555	COG0275	rRNA processing
EL289_RS08565	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EL289_RS08570	COG0454	-acetyltransferase
EL289_RS08575	COG1011	Hydrolase
EL289_RS08615	COG1388	LysM domain
EL289_RS08615	COG0860	N-Acetylmuramoyl-L-alanine amidase
EL289_RS08650	COG5434	Belongs to the glycosyl hydrolase 28 family
EL289_RS08670	COG5280	Phage tail tape measure protein TP901
EL289_RS08670	COG3953	SLT domain
EL289_RS08755	COG0756	dUTP diphosphatase activity
EL289_RS08820	COG1484	DNA-dependent DNA replication
EL289_RS08890	COG3561	AntA/AntB antirepressor
EL289_RS08900	COG1396	sequence-specific DNA binding
EL289_RS08920	COG0582	viral genome integration into host DNA
EL289_RS08930	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EL289_RS08935	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EL289_RS08940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EL289_RS08945	COG1053	succinate dehydrogenase
EL289_RS08950	COG2009	succinate dehydrogenase
EL289_RS08955	COG0322	excinuclease ABC activity
EL289_RS08960	COG3118	belongs to the thioredoxin family
EL289_RS08965	COG1193	negative regulation of DNA recombination
EL289_RS08970	COG1796	DNA polymerase
EL289_RS08970	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EL289_RS08980	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EL289_RS08985	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EL289_RS08990	COG0072	phenylalanine-tRNA ligase activity
EL289_RS08990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL289_RS08995	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EL289_RS09000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EL289_RS09010	COG4509	Sortase family
EL289_RS09015	COG1120	ATPase activity
EL289_RS09040	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EL289_RS09040	COG3583	domain protein
EL289_RS09040	COG4932	domain protein
EL289_RS09055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EL289_RS09075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EL289_RS09080	COG0742	ribosomal rna small subunit methyltransferase
EL289_RS09090	COG4471	UPF0298 protein
EL289_RS09095	COG0584	glycerophosphoryl diester phosphodiesterase
EL289_RS09140	COG3679	Belongs to the UPF0342 family
EL289_RS09155	COG0109	protoheme IX farnesyltransferase activity
EL289_RS09160	COG1612	heme a metabolic process
EL289_RS09170	COG0772	Belongs to the SEDS family
EL289_RS09175	COG4838	Belongs to the UPF0358 family
EL289_RS09180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EL289_RS09185	COG4896	Protein conserved in bacteria
EL289_RS09190	COG1217	gtp-binding protein TYPA
EL289_RS09200	COG0483	inositol monophosphate 1-phosphatase activity
EL289_RS09205	COG4493	Belongs to the UPF0637 family
EL289_RS09210	COG1914	H( )-stimulated, divalent metal cation uptake system
EL289_RS09230	COG1177	transmembrane transport
EL289_RS09235	COG1176	ABC-type spermidine putrescine transport system, permease component I
EL289_RS09245	COG1396	sequence-specific DNA binding
EL289_RS09245	COG3800	Transcriptional regulator
EL289_RS09250	COG4476	Belongs to the UPF0223 family
EL289_RS09260	COG0508	dehydrogenase complex catalyzes the overall conversion of
EL289_RS09265	COG0022	dehydrogenase e1 component
EL289_RS09270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EL289_RS09280	COG0242	peptide deformylase activity
EL289_RS09285	COG5503	Protein of unknown function (DUF1447)
EL289_RS09290	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EL289_RS09295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EL289_RS09300	COG0569	domain protein
EL289_RS09305	COG1294	oxidase, subunit
EL289_RS09310	COG1271	oxidase subunit
EL289_RS09325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL289_RS09335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EL289_RS09355	COG4172	Belongs to the ABC transporter superfamily
EL289_RS09360	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EL289_RS09365	COG0151	Belongs to the GarS family
EL289_RS09370	COG0138	bifunctional purine biosynthesis protein purh
EL289_RS09375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EL289_RS09380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EL289_RS09385	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EL289_RS09390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EL289_RS09395	COG0047	phosphoribosylformylglycinamidine synthase activity
EL289_RS09400	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EL289_RS09405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EL289_RS09410	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EL289_RS09415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EL289_RS09420	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EL289_RS09425	COG1017	nitric oxide dioxygenase activity
EL289_RS09425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EL289_RS09435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EL289_RS09440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EL289_RS09450	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EL289_RS09465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EL289_RS09470	COG1316	TRANSCRIPTIONal
EL289_RS09490	COG1846	Transcriptional regulator
EL289_RS09495	COG3594	Acyltransferase
EL289_RS09500	COG0436	Aminotransferase
EL289_RS09505	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EL289_RS09515	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EL289_RS09520	COG1169	isochorismate synthase
EL289_RS09525	COG1575	Belongs to the MenA family. Type 1 subfamily
EL289_RS09570	COG4873	Protein conserved in bacteria
EL289_RS09580	COG0737	Belongs to the 5'-nucleotidase family
EL289_RS09585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EL289_RS09590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EL289_RS09595	COG0861	Integral membrane protein TerC family
EL289_RS09600	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EL289_RS09610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EL289_RS09615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EL289_RS09620	COG2814	Major facilitator Superfamily
EL289_RS09625	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EL289_RS09630	COG2382	esterase
EL289_RS09635	COG0628	permease
EL289_RS09645	COG0475	glutathione-regulated potassium exporter activity
EL289_RS09645	COG0569	domain protein
EL289_RS09650	COG2239	Acts as a magnesium transporter
EL289_RS09655	COG0564	pseudouridine synthase activity
EL289_RS09665	COG2357	RelA SpoT domain protein
EL289_RS09680	COG2346	COG2346, Truncated hemoglobins
EL289_RS09685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EL289_RS09690	COG1164	Oligoendopeptidase f
EL289_RS09700	COG4862	establishment of competence for transformation
EL289_RS09705	COG1393	Belongs to the ArsC family
EL289_RS09710	COG0180	Tryptophanyl-tRNA synthetase
EL289_RS09715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EL289_RS09720	COG0601	transmembrane transport
EL289_RS09725	COG4608	Belongs to the ABC transporter superfamily
EL289_RS09730	COG0444	Belongs to the ABC transporter superfamily
EL289_RS09745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EL289_RS09755	COG1881	PFAM PEBP family protein
EL289_RS09760	COG0542	response to heat
EL289_RS09775	COG0561	phosphatase activity
EL289_RS09780	COG0446	pyridine nucleotide-disulphide oxidoreductase
EL289_RS09790	COG0179	Fumarylacetoacetate (FAA) hydrolase
EL289_RS09795	COG1074	ATP-dependent DNA helicase activity
EL289_RS09800	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EL289_RS09815	COG0398	Pfam SNARE associated Golgi protein
EL289_RS09820	COG0166	Belongs to the GPI family
EL289_RS09825	COG0137	argininosuccinate synthase activity
EL289_RS09830	COG0165	Argininosuccinate lyase
EL289_RS09835	COG0584	glycerophosphoryl diester phosphodiesterase
EL289_RS09850	COG1902	pentaerythritol trinitrate reductase activity
EL289_RS09855	COG1098	S1 RNA binding domain
EL289_RS09860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EL289_RS09870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EL289_RS09870	COG2111	Na H antiporter
EL289_RS09875	COG2111	Na H antiporter
EL289_RS09880	COG1006	Multisubunit Na H antiporter MnhC subunit
EL289_RS09885	COG0651	ATP synthesis coupled electron transport
EL289_RS09890	COG1863	multisubunit Na H antiporter MnhE subunit
EL289_RS09895	COG2212	antiporter activity
EL289_RS09900	COG1320	monovalent cation:proton antiporter activity
EL289_RS09910	COG2050	protein possibly involved in aromatic compounds catabolism
EL289_RS09915	COG2056	Na+-H+ antiporter family
EL289_RS09920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EL289_RS09925	COG1252	NADH dehydrogenase
EL289_RS09930	COG0316	Belongs to the HesB IscA family
EL289_RS09935	COG4844	belongs to the
EL289_RS09940	COG1252	NADH dehydrogenase
EL289_RS09945	COG4837	Protein of unknown function (DUF1462)
EL289_RS09950	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EL289_RS09955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EL289_RS09965	COG1696	Membrane protein involved in D-alanine export
EL289_RS09970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EL289_RS09985	COG0647	UMP catabolic process
EL289_RS09990	COG2445	Protein of unknown function DUF86
EL289_RS10000	COG4470	Protein conserved in bacteria
EL289_RS10005	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EL289_RS10010	COG0737	Belongs to the 5'-nucleotidase family
EL289_RS10015	COG0730	response to heat
EL289_RS10020	COG1801	Protein of unknown function DUF72
EL289_RS10025	COG2070	2-Nitropropane dioxygenase
EL289_RS10030	COG1253	flavin adenine dinucleotide binding
EL289_RS10120	COG3942	CHAP domain
EL289_RS10120	COG1388	LysM domain
EL289_RS10130	COG0719	Fe-S assembly protein
EL289_RS10135	COG0822	iron-sulfur transferase activity
EL289_RS10140	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EL289_RS10145	COG0719	Fe-S assembly protein
EL289_RS10150	COG0396	ATPase activity
EL289_RS10165	COG1464	Belongs to the NlpA lipoprotein family
EL289_RS10170	COG2011	ABC-type metal ion transport system permease component
EL289_RS10175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EL289_RS10185	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EL289_RS10190	COG0509	glycine decarboxylation via glycine cleavage system
EL289_RS10195	COG1393	Belongs to the ArsC family
EL289_RS10200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL289_RS10210	COG0710	3-dehydroquinate dehydratase activity
EL289_RS10215	COG1764	response to oxidative stress
EL289_RS10225	COG1279	arginine transmembrane transporter activity
EL289_RS10230	COG0406	alpha-ribazole phosphatase activity
EL289_RS10265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EL289_RS10270	COG4195	phage-related replication protein
EL289_RS10295	COG1278	Cold shock
EL289_RS10345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EL289_RS10350	COG0557	exoribonuclease II activity
EL289_RS10355	COG1647	Serine aminopeptidase, S33
EL289_RS10360	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EL289_RS10370	COG0148	phosphopyruvate hydratase activity
EL289_RS10375	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EL289_RS10380	COG0149	triose-phosphate isomerase activity
EL289_RS10385	COG0126	phosphoglycerate kinase activity
EL289_RS10390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EL289_RS10410	COG1090	epimerase
EL289_RS10420	COG0740	serine-type endopeptidase activity
EL289_RS10430	COG1481	regulation of sporulation
EL289_RS10435	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EL289_RS10440	COG1660	Displays ATPase and GTPase activities
EL289_RS10445	COG0492	ferredoxin-NADP+ reductase activity
EL289_RS10460	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EL289_RS10465	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EL289_RS10470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EL289_RS10475	COG0556	nucleotide-excision repair
EL289_RS10490	COG1388	LysM domain
EL289_RS10490	COG3942	CHAP domain
EL289_RS10500	COG0653	protein targeting
EL289_RS10510	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EL289_RS10515	COG1040	competence protein
EL289_RS10520	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EL289_RS10530	COG1739	Uncharacterized protein family UPF0029
EL289_RS10535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EL289_RS10540	COG2199	diguanylate cyclase activity
EL289_RS10555	COG2195	Cleaves the N-terminal amino acid of tripeptides
EL289_RS10560	COG1929	Belongs to the glycerate kinase type-1 family
EL289_RS10580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EL289_RS10595	COG4604	ABC transporter, ATP-binding protein
EL289_RS10600	COG4605	iron ion homeostasis
EL289_RS10605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL289_RS10615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EL289_RS10620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EL289_RS10625	COG1780	Probably involved in ribonucleotide reductase function
EL289_RS10635	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EL289_RS10640	COG3104	oligopeptide transport
EL289_RS10645	COG1597	lipid kinase activity
EL289_RS10655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EL289_RS10660	COG1174	glycine betaine transport
EL289_RS10670	COG0514	ATP-dependent DNA helicase (RecQ)
EL289_RS10675	COG0488	(ABC) transporter
EL289_RS10685	COG1368	sulfuric ester hydrolase activity
EL289_RS10710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EL289_RS10720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EL289_RS10725	COG0720	synthase
EL289_RS10730	COG0602	queuosine metabolic process
EL289_RS10750	COG0745	RESPONSE REGULATOR receiver
EL289_RS10755	COG5002	protein histidine kinase activity
EL289_RS10760	COG0463	Glycosyl transferase, family 2
EL289_RS10765	COG0656	L-ascorbic acid biosynthetic process
EL289_RS10770	COG1253	flavin adenine dinucleotide binding
EL289_RS10775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EL289_RS10780	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL289_RS10780	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL289_RS10780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL289_RS10785	COG1105	Belongs to the carbohydrate kinase PfkB family
EL289_RS10790	COG1349	DNA-binding transcription factor activity
EL289_RS10795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EL289_RS10825	COG0415	Belongs to the DNA photolyase family
EL289_RS10830	COG0471	metal ion transport
EL289_RS10835	COG0039	L-malate dehydrogenase activity
EL289_RS10845	COG0523	cobalamin synthesis protein
EL289_RS10855	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EL289_RS10860	COG4988	ABC transporter
EL289_RS10865	COG1968	undecaprenyl-diphosphatase activity
EL289_RS10875	COG1671	Belongs to the UPF0178 family
EL289_RS10880	COG1611	Belongs to the LOG family
EL289_RS10885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EL289_RS10910	COG2839	Protein conserved in bacteria
EL289_RS10915	COG2814	Major facilitator Superfamily
EL289_RS10920	COG0583	DNA-binding transcription factor activity
EL289_RS10935	COG0217	transcriptional regulatory protein
EL289_RS10945	COG1917	Cupin 2, conserved barrel domain protein
EL289_RS10945	COG4977	sequence-specific DNA binding
EL289_RS10955	COG3942	CHAP domain
EL289_RS10955	COG1388	LysM domain
EL289_RS10960	COG0306	phosphate transporter
EL289_RS10965	COG1392	Phosphate transport regulator
EL289_RS10970	COG0577	efflux transmembrane transporter activity
EL289_RS10975	COG1136	(ABC) transporter
EL289_RS10980	COG2205	protein histidine kinase activity
EL289_RS10985	COG0745	RESPONSE REGULATOR receiver
EL289_RS10990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EL289_RS11000	COG0657	acetylesterase activity
EL289_RS11005	COG3949	Membrane
EL289_RS11015	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EL289_RS11020	COG1461	Dihydroxyacetone kinase
EL289_RS11025	COG2376	Dihydroxyacetone kinase
EL289_RS11030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL289_RS11035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL289_RS11040	COG1120	ATPase activity
EL289_RS11045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EL289_RS11055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EL289_RS11060	COG1132	(ABC) transporter
EL289_RS11065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EL289_RS11075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EL289_RS11080	COG1682	transport, permease protein
EL289_RS11085	COG1134	teichoic acid transport
EL289_RS11090	COG5609	conserved protein (DUF2294)
EL289_RS11100	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EL289_RS11110	COG1321	iron dependent repressor
EL289_RS11115	COG1121	(ABC) transporter
EL289_RS11120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EL289_RS11125	COG0803	Belongs to the bacterial solute-binding protein 9 family
EL289_RS11135	COG1320	monovalent cation:proton antiporter activity
EL289_RS11140	COG2212	antiporter activity
EL289_RS11145	COG1863	multisubunit Na H antiporter MnhE subunit
EL289_RS11150	COG0651	ATP synthesis coupled electron transport
EL289_RS11155	COG1006	Multisubunit Na H antiporter MnhC subunit
EL289_RS11160	COG2111	Na H antiporter
EL289_RS11165	COG2111	Na H antiporter
EL289_RS11165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EL289_RS11170	COG0582	viral genome integration into host DNA
EL289_RS11200	COG0596	Alpha beta hydrolase
EL289_RS11215	COG2267	carboxylic ester hydrolase activity
EL289_RS11220	COG0546	phosphoglycolate phosphatase activity
EL289_RS11225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL289_RS11230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EL289_RS11245	COG0789	Transcriptional regulator
EL289_RS11250	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EL289_RS11255	COG0018	arginyl-trna synthetase
EL289_RS11275	COG3875	lactate racemase activity
EL289_RS11280	COG1606	tRNA processing
EL289_RS11285	COG1691	(AIR) carboxylase
EL289_RS11290	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EL289_RS11305	COG1078	dGTPase activity
EL289_RS11315	COG0655	NAD(P)H dehydrogenase (quinone) activity
EL289_RS11325	COG0667	Aldo Keto reductase
EL289_RS11340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EL289_RS11345	COG4844	belongs to the
EL289_RS11365	COG0095	Lipoate-protein ligase
EL289_RS11370	COG0280	phosphate acetyltransferase
EL289_RS11375	COG3253	May function as heme-dependent peroxidase
EL289_RS11395	COG2363	Small membrane protein
EL289_RS11405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EL289_RS11410	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EL289_RS11415	COG0351	phosphomethylpyrimidine kinase
EL289_RS11420	COG0477	Major facilitator Superfamily
EL289_RS11435	COG0183	Belongs to the thiolase family
EL289_RS11440	COG0318	PFAM AMP-dependent synthetase and ligase
EL289_RS11455	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EL289_RS11460	COG0363	glucosamine-6-phosphate deaminase activity
EL289_RS11470	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EL289_RS11480	COG2271	Major facilitator Superfamily
EL289_RS11490	COG0431	NADPH-dependent FMN reductase
EL289_RS11495	COG0561	phosphatase activity
EL289_RS11505	COG1428	Deoxynucleoside kinase
EL289_RS11510	COG1428	Deoxynucleoside kinase
EL289_RS11515	COG1028	Short-chain dehydrogenase reductase Sdr
EL289_RS11520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EL289_RS11525	COG0546	phosphoglycolate phosphatase activity
EL289_RS11530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EL289_RS11540	COG0737	Belongs to the 5'-nucleotidase family
EL289_RS11545	COG1069	ribulokinase activity
EL289_RS11550	COG1063	alcohol dehydrogenase
EL289_RS11555	COG2814	Major facilitator Superfamily
EL289_RS11560	COG1349	DNA-binding transcription factor activity
EL289_RS11590	COG1473	amidohydrolase
EL289_RS11595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EL289_RS11600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EL289_RS11610	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EL289_RS11620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EL289_RS11625	COG0085	RNA polymerase activity
EL289_RS11630	COG2813	Specifically methylates the guanine in position
EL289_RS11635	COG0222	ribosome binding
EL289_RS11640	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EL289_RS11650	COG0081	regulation of translation
EL289_RS11655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EL289_RS11660	COG0250	Participates in transcription elongation, termination and antitermination
EL289_RS11665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EL289_RS11670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EL289_RS11680	COG3688	RNA-binding protein containing a PIN domain
EL289_RS11685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EL289_RS11690	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EL289_RS11695	COG0215	cysteine-tRNA ligase activity
EL289_RS11700	COG1045	serine acetyltransferase
EL289_RS11705	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EL289_RS11710	COG4956	integral membrane protein (PIN domain superfamily)
EL289_RS11715	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EL289_RS11720	COG0542	response to heat
EL289_RS11725	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EL289_RS11730	COG3880	PFAM UvrB UvrC protein
EL289_RS11740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EL289_RS11745	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EL289_RS11750	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EL289_RS11755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EL289_RS11825	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EL289_RS11830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EL289_RS11835	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EL289_RS11840	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EL289_RS11850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EL289_RS11855	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EL289_RS11860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EL289_RS11870	COG0037	tRNA processing
EL289_RS11875	COG1098	S1 RNA binding domain
EL289_RS11885	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EL289_RS11890	COG3956	TIGRFAM MazG family protein
EL289_RS11895	COG2244	polysaccharide biosynthetic process
EL289_RS11900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EL289_RS11905	COG0193	aminoacyl-tRNA hydrolase activity
EL289_RS11910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EL289_RS11915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EL289_RS11920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EL289_RS11925	COG2088	sporulation resulting in formation of a cellular spore
EL289_RS11930	COG0251	oxidation-reduction process
EL289_RS11935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EL289_RS11940	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EL289_RS11945	COG4466	Protein conserved in bacteria
EL289_RS11950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EL289_RS11955	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EL289_RS11960	COG0084	hydrolase, TatD family'
EL289_RS11965	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL289_RS11965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL289_RS11970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EL289_RS11975	COG2827	Endonuclease containing a URI domain
EL289_RS11980	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EL289_RS11985	COG4467	Involved in initiation control of chromosome replication
EL289_RS11990	COG1774	PSP1 C-terminal conserved region
EL289_RS11995	COG0470	DNA polymerase III
EL289_RS12000	COG3870	Protein conserved in bacteria
EL289_RS12005	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EL289_RS12010	COG1982	Orn Lys Arg decarboxylase major
EL289_RS12035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EL289_RS12040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EL289_RS12045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EL289_RS12060	COG2188	Transcriptional regulator
EL289_RS12065	COG0366	Alpha amylase catalytic
EL289_RS12070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL289_RS12070	COG1263	PTS System
EL289_RS12080	COG0493	'glutamate synthase
EL289_RS12085	COG0069	glutamate synthase activity
EL289_RS12085	COG0070	glutamate synthase
EL289_RS12085	COG0067	glutamate synthase
EL289_RS12090	COG0583	DNA-binding transcription factor activity
EL289_RS12105	COG0456	acetyltransferase
EL289_RS12120	COG0438	transferase activity, transferring glycosyl groups
EL289_RS12125	COG1388	LysM domain
EL289_RS12125	COG3942	CHAP domain
EL289_RS12135	COG2011	ABC-type metal ion transport system permease component
EL289_RS12140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EL289_RS12145	COG0626	cystathionine gamma-synthase activity
EL289_RS12150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EL289_RS12165	COG0733	neurotransmitter:sodium symporter activity
EL289_RS12175	COG1647	Serine aminopeptidase, S33
EL289_RS12195	COG5609	conserved protein (DUF2294)
EL289_RS12200	COG3002	Belongs to the UPF0753 family
EL289_RS12205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EL289_RS12225	COG2814	Major facilitator Superfamily
EL289_RS12230	COG0523	cobalamin synthesis protein
EL289_RS12240	COG2211	Major facilitator Superfamily
EL289_RS12250	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EL289_RS12265	COG0519	Catalyzes the synthesis of GMP from XMP
EL289_RS12265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EL289_RS12270	COG0516	GMP reductase activity
EL289_RS12270	COG0517	IMP dehydrogenase activity
EL289_RS12275	COG2233	PERMEase
EL289_RS12280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EL289_RS12295	COG5183	chlorophyll binding
EL289_RS12300	COG1823	symporter activity
EL289_RS12305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EL289_RS12310	COG0778	Nitroreductase
EL289_RS12320	COG0450	alkyl hydroperoxide reductase
EL289_RS12325	COG3634	alkyl hydroperoxide reductase activity
EL289_RS12345	COG1280	lysine exporter protein (LysE YggA)
EL289_RS12490	COG0582	viral genome integration into host DNA
EL289_RS12500	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EL289_RS12510	COG0360	Binds together with S18 to 16S ribosomal RNA
EL289_RS12525	COG0012	GTP binding
EL289_RS12530	COG4481	Protein conserved in bacteria
EL289_RS12535	COG0668	transmembrane transport
EL289_RS12540	COG1475	DNA binding
EL289_RS12550	COG0626	cystathionine gamma-synthase activity
EL289_RS12555	COG0626	cystathionine gamma-synthase activity
EL289_RS12560	COG0646	methionine synthase
EL289_RS12560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EL289_RS12565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EL289_RS12575	COG0183	Belongs to the thiolase family
EL289_RS12590	COG1476	TRANSCRIPTIONal
EL289_RS12600	COG1131	(ABC) transporter
EL289_RS12610	COG2814	Major facilitator Superfamily
EL289_RS12650	COG1136	(ABC) transporter
EL289_RS12655	COG0577	efflux transmembrane transporter activity
EL289_RS12680	COG0577	efflux transmembrane transporter activity
EL289_RS12685	COG1136	(ABC) transporter
EL289_RS12690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL289_RS12740	COG1475	DNA binding
EL289_RS12745	COG0357	Ribosomal RNA small subunit methyltransferase G
EL289_RS12750	COG0445	tRNA wobble uridine modification
EL289_RS12755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EL289_RS12760	COG0594	ribonuclease P activity