locus-tag	class	description
BEK99_RS00025	COG0069	glutamate synthase activity
BEK99_RS00030	COG2814	Major facilitator Superfamily
BEK99_RS00040	COG2837	iron assimilation
BEK99_RS00045	COG0672	)-iron permease
BEK99_RS00050	COG0805	protein transport
BEK99_RS00055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BEK99_RS00060	COG4336	lyase activity
BEK99_RS00065	COG0753	catalase activity
BEK99_RS00075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BEK99_RS00120	COG0201	protein transport
BEK99_RS00130	COG1073	alpha beta
BEK99_RS00190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BEK99_RS00195	COG2011	ABC-type metal ion transport system permease component
BEK99_RS00230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BEK99_RS00235	COG1216	Glycosyl transferase, family 2
BEK99_RS00240	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BEK99_RS00255	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BEK99_RS00320	COG3961	Belongs to the TPP enzyme family
BEK99_RS00330	COG1510	regulation of RNA biosynthetic process
BEK99_RS00335	COG1012	belongs to the aldehyde dehydrogenase family
BEK99_RS00340	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BEK99_RS00345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BEK99_RS00350	COG1181	Belongs to the D-alanine--D-alanine ligase family
BEK99_RS00380	COG1368	sulfuric ester hydrolase activity
BEK99_RS00390	COG2409	Drug exporters of the RND superfamily
BEK99_RS00395	COG0463	Glycosyl transferase, family 2
BEK99_RS00395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BEK99_RS00400	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BEK99_RS00400	COG0463	Glycosyl transferase, family 2
BEK99_RS00410	COG0494	nUDIX hydrolase
BEK99_RS00420	COG0563	adenylate kinase activity
BEK99_RS00430	COG3588	fructose-bisphosphate aldolase
BEK99_RS00435	COG2258	MOSC domain
BEK99_RS00460	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BEK99_RS00465	COG1263	PTS System
BEK99_RS00465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BEK99_RS00470	COG1737	Transcriptional regulator
BEK99_RS00510	COG0582	viral genome integration into host DNA
BEK99_RS00515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BEK99_RS00515	COG2111	Na H antiporter
BEK99_RS00520	COG2111	Na H antiporter
BEK99_RS00525	COG1006	Multisubunit Na H antiporter MnhC subunit
BEK99_RS00535	COG1863	multisubunit Na H antiporter MnhE subunit
BEK99_RS00540	COG2212	antiporter activity
BEK99_RS00545	COG1320	monovalent cation:proton antiporter activity
BEK99_RS00560	COG1113	amino acid transport
BEK99_RS00585	COG2824	Alkylphosphonate utilization operon protein PhnA
BEK99_RS00595	COG2376	Dihydroxyacetone kinase
BEK99_RS00600	COG1461	Dihydroxyacetone kinase
BEK99_RS00615	COG0463	Glycosyl transferase, family 2
BEK99_RS00615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BEK99_RS00620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BEK99_RS00630	COG0531	amino acid
BEK99_RS00650	COG0463	Glycosyl transferase, family 2
BEK99_RS00655	COG0446	pyridine nucleotide-disulphide oxidoreductase
BEK99_RS00665	COG1959	2 iron, 2 sulfur cluster binding
BEK99_RS00670	COG1131	(ABC) transporter
BEK99_RS00690	COG1028	Short-chain dehydrogenase reductase Sdr
BEK99_RS00710	COG0318	PFAM AMP-dependent synthetase and ligase
BEK99_RS00715	COG0183	Belongs to the thiolase family
BEK99_RS00725	COG2235	arginine
BEK99_RS00730	COG2235	arginine
BEK99_RS00740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BEK99_RS00745	COG1438	arginine binding
BEK99_RS00760	COG2022	thiamine diphosphate biosynthetic process
BEK99_RS00770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BEK99_RS00790	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BEK99_RS00830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BEK99_RS00840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BEK99_RS00845	COG2508	Transcriptional regulator
BEK99_RS00850	COG1953	Uracil, thiamine, allantoin
BEK99_RS00860	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BEK99_RS00865	COG1984	allophanate hydrolase subunit 2
BEK99_RS00870	COG0439	Biotin carboxylase
BEK99_RS00875	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BEK99_RS00880	COG1914	H( )-stimulated, divalent metal cation uptake system
BEK99_RS00885	COG1070	Carbohydrate kinase
BEK99_RS00900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BEK99_RS00910	COG1695	Transcriptional regulator
BEK99_RS00935	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BEK99_RS00950	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BEK99_RS00965	COG3189	MarR family transcriptional regulator
BEK99_RS00990	COG0604	alcohol dehydrogenase
BEK99_RS00995	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BEK99_RS01000	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BEK99_RS01010	COG3001	Fructosamine kinase
BEK99_RS01025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BEK99_RS01040	COG3764	Sortase (surface protein transpeptidase)
BEK99_RS01045	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BEK99_RS01055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BEK99_RS01075	COG1136	(ABC) transporter
BEK99_RS01080	COG0577	efflux transmembrane transporter activity
BEK99_RS01085	COG0583	DNA-binding transcription factor activity
BEK99_RS01100	COG0028	Belongs to the TPP enzyme family
BEK99_RS01110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BEK99_RS01120	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BEK99_RS01125	COG1687	branched-chain amino acid
BEK99_RS01130	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BEK99_RS01155	COG1760	l-serine dehydratase
BEK99_RS01160	COG1760	l-serine dehydratase
BEK99_RS01170	COG0778	Nitroreductase
BEK99_RS01185	COG1132	(ABC) transporter
BEK99_RS01195	COG0803	Belongs to the bacterial solute-binding protein 9 family
BEK99_RS01200	COG1846	Transcriptional regulator
BEK99_RS01205	COG0346	lactoylglutathione lyase activity
BEK99_RS01210	COG2211	Major facilitator Superfamily
BEK99_RS01215	COG2207	Transcriptional regulator
BEK99_RS01225	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BEK99_RS01230	COG1131	(ABC) transporter
BEK99_RS01240	COG0586	Pfam SNARE associated Golgi protein
BEK99_RS01255	COG3527	Alpha-acetolactate decarboxylase
BEK99_RS01265	COG4876	unkown
BEK99_RS01270	COG0523	cobalamin synthesis protein
BEK99_RS01275	COG2357	RelA SpoT domain protein
BEK99_RS01290	COG2808	Putative FMN-binding domain
BEK99_RS01300	COG1070	Carbohydrate kinase
BEK99_RS01305	COG2610	gluconate transmembrane transporter activity
BEK99_RS01315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BEK99_RS01320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BEK99_RS01345	COG4619	ABC transporter
BEK99_RS01350	COG0390	transport system, permease component
BEK99_RS01355	COG2814	Major facilitator Superfamily
BEK99_RS01360	COG2272	Belongs to the type-B carboxylesterase lipase family
BEK99_RS01370	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BEK99_RS01380	COG1174	glycine betaine transport
BEK99_RS01390	COG1174	glycine betaine transport
BEK99_RS01400	COG1309	transcriptional regulator
BEK99_RS01415	COG1346	cytolysis
BEK99_RS01425	COG3279	Response regulator of the LytR AlgR family
BEK99_RS01430	COG3275	phosphorelay sensor kinase activity
BEK99_RS01450	COG0531	amino acid
BEK99_RS01455	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BEK99_RS01460	COG1113	amino acid transport
BEK99_RS01470	COG2814	Major facilitator Superfamily
BEK99_RS01480	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BEK99_RS01485	COG0741	lytic transglycosylase activity
BEK99_RS01490	COG0588	phosphoglycerate mutase activity
BEK99_RS01495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BEK99_RS01500	COG0765	amino acid transport
BEK99_RS01505	COG1126	abc transporter atp-binding protein
BEK99_RS01530	COG2353	YceI-like domain
BEK99_RS01545	COG2116	formate transmembrane transporter activity
BEK99_RS01560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BEK99_RS01565	COG2146	nitrite reductase [NAD(P)H] activity
BEK99_RS01570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BEK99_RS01570	COG1648	precorrin-2 dehydrogenase activity
BEK99_RS01575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BEK99_RS01580	COG1140	nitrate reductase beta subunit
BEK99_RS01590	COG2181	nitrate reductase activity
BEK99_RS01600	COG4585	Histidine kinase
BEK99_RS01605	COG2197	response regulator
BEK99_RS01610	COG2223	nitrite transmembrane transporter activity
BEK99_RS01615	COG0772	Belongs to the SEDS family
BEK99_RS01620	COG3425	synthase
BEK99_RS01640	COG1846	Transcriptional regulator
BEK99_RS01650	COG0697	spore germination
BEK99_RS01685	COG0492	ferredoxin-NADP+ reductase activity
BEK99_RS01690	COG2814	Major facilitator Superfamily
BEK99_RS01695	COG0604	alcohol dehydrogenase
BEK99_RS01705	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BEK99_RS01710	COG1620	l-lactate permease
BEK99_RS01715	COG0438	transferase activity, transferring glycosyl groups
BEK99_RS01725	COG3850	Histidine kinase
BEK99_RS01725	COG5002	protein histidine kinase activity
BEK99_RS01730	COG0745	RESPONSE REGULATOR receiver
BEK99_RS01735	COG0577	efflux transmembrane transporter activity
BEK99_RS01740	COG1136	(ABC) transporter
BEK99_RS01755	COG4640	response to antibiotic
BEK99_RS01760	COG2814	Major facilitator Superfamily
BEK99_RS01765	COG1033	growth of symbiont in host cell
BEK99_RS01765	COG2409	Drug exporters of the RND superfamily
BEK99_RS01775	COG1566	PFAM secretion protein HlyD family protein
BEK99_RS01780	COG2814	Major facilitator Superfamily
BEK99_RS01800	COG0598	Magnesium transport protein CorA
BEK99_RS01805	COG1304	FMN binding
BEK99_RS01815	COG1328	CTP reductase activity
BEK99_RS01820	COG0602	queuosine metabolic process
BEK99_RS01825	COG2094	Belongs to the DNA glycosylase MPG family
BEK99_RS01830	COG3152	Membrane
BEK99_RS01855	COG4152	abc transporter atp-binding protein
BEK99_RS01860	COG1668	transmembrane transport
BEK99_RS01865	COG1742	UPF0060 membrane protein
BEK99_RS01870	COG2017	converts alpha-aldose to the beta-anomer
BEK99_RS01875	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BEK99_RS01880	COG1266	CAAX protease self-immunity
BEK99_RS01885	COG0010	Belongs to the arginase family
BEK99_RS01890	COG0583	DNA-binding transcription factor activity
BEK99_RS01895	COG3314	Sporulation integral membrane protein YlbJ
BEK99_RS01900	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BEK99_RS01910	COG0659	secondary active sulfate transmembrane transporter activity
BEK99_RS01915	COG1473	amidohydrolase
BEK99_RS01920	COG1028	Short-chain dehydrogenase reductase Sdr
BEK99_RS01925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEK99_RS01940	COG2271	Major facilitator Superfamily
BEK99_RS01950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BEK99_RS01975	COG1113	amino acid transport
BEK99_RS01980	COG1737	Transcriptional regulator
BEK99_RS02015	COG3383	formate dehydrogenase (NAD+) activity
BEK99_RS02040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BEK99_RS02045	COG2076	Multidrug Resistance protein
BEK99_RS02050	COG2076	Multidrug Resistance protein
BEK99_RS02065	COG1757	Na H antiporter
BEK99_RS02075	COG3942	CHAP domain
BEK99_RS02105	COG0830	nickel cation binding
BEK99_RS02110	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BEK99_RS02115	COG0804	urea catabolic process
BEK99_RS02125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BEK99_RS02130	COG1960	acyl-CoA dehydrogenase activity
BEK99_RS02135	COG1957	nucleoside hydrolase
BEK99_RS02140	COG1268	BioY protein
BEK99_RS02150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BEK99_RS02155	COG1609	Transcriptional regulator
BEK99_RS02160	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BEK99_RS02165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BEK99_RS02170	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BEK99_RS02180	COG4149	molybdate abc transporter
BEK99_RS02185	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BEK99_RS02190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BEK99_RS02195	COG0521	Mo-molybdopterin cofactor biosynthetic process
BEK99_RS02200	COG0315	cyclic pyranopterin monophosphate synthase activity
BEK99_RS02215	COG0314	molybdopterin synthase activity
BEK99_RS02225	COG0746	molybdenum cofactor guanylyltransferase activity
BEK99_RS02230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BEK99_RS02240	COG2814	Major facilitator Superfamily
BEK99_RS02260	COG2348	transferase activity, transferring amino-acyl groups
BEK99_RS02265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BEK99_RS02295	COG4975	Glucose uptake
BEK99_RS02305	COG0551	DNA topoisomerase type I activity
BEK99_RS02305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BEK99_RS02310	COG2252	PERMEase
BEK99_RS02325	COG0051	transcription antitermination factor activity, RNA binding
BEK99_RS02330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BEK99_RS02335	COG0088	Forms part of the polypeptide exit tunnel
BEK99_RS02340	COG0089	rRNA binding
BEK99_RS02345	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BEK99_RS02350	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BEK99_RS02355	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BEK99_RS02360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BEK99_RS02365	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BEK99_RS02375	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BEK99_RS02380	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BEK99_RS02385	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BEK99_RS02390	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BEK99_RS02395	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BEK99_RS02400	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BEK99_RS02405	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BEK99_RS02410	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BEK99_RS02415	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BEK99_RS02420	COG1841	ribosomal large subunit assembly
BEK99_RS02425	COG0200	Binds to the 23S rRNA
BEK99_RS02430	COG0201	protein transport
BEK99_RS02435	COG0563	adenylate kinase activity
BEK99_RS02445	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BEK99_RS02450	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BEK99_RS02455	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BEK99_RS02460	COG0202	RNA polymerase activity
BEK99_RS02465	COG0203	ribosomal protein L17
BEK99_RS02485	COG0101	tRNA pseudouridine synthase activity
BEK99_RS02490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BEK99_RS02495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BEK99_RS02500	COG1846	Transcriptional regulator
BEK99_RS02505	COG2814	Major facilitator Superfamily
BEK99_RS02510	COG1335	isochorismatase
BEK99_RS02530	COG2318	DinB family
BEK99_RS02540	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BEK99_RS02545	COG2130	NADP-dependent
BEK99_RS02555	COG2130	NADP-dependent
BEK99_RS02560	COG0604	alcohol dehydrogenase
BEK99_RS02580	COG1302	Protein conserved in bacteria
BEK99_RS02590	COG2814	Major facilitator Superfamily
BEK99_RS02595	COG4264	IucA IucC family
BEK99_RS02600	COG3457	Alanine racemase
BEK99_RS02605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BEK99_RS02610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEK99_RS02615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEK99_RS02620	COG3314	Sporulation integral membrane protein YlbJ
BEK99_RS02625	COG2329	Antibiotic biosynthesis monooxygenase
BEK99_RS02640	COG1988	membrane-bound metal-dependent
BEK99_RS02645	COG4284	Utp--glucose-1-phosphate uridylyltransferase
BEK99_RS02665	COG2814	Major facilitator Superfamily
BEK99_RS02670	COG0489	protein tyrosine kinase activity
BEK99_RS02720	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BEK99_RS02725	COG4856	YbbR-like protein
BEK99_RS02730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BEK99_RS02735	COG1285	pathogenesis
BEK99_RS02745	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BEK99_RS02750	COG3711	transcriptional antiterminator
BEK99_RS02790	COG0640	Transcriptional regulator
BEK99_RS02795	COG0702	epimerase
BEK99_RS02800	COG2186	Transcriptional regulator
BEK99_RS02805	COG1482	cell wall glycoprotein biosynthetic process
BEK99_RS02825	COG0783	Belongs to the Dps family
BEK99_RS02830	COG1876	peptidase activity
BEK99_RS02835	COG0813	purine-nucleoside phosphorylase activity
BEK99_RS02840	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BEK99_RS02850	COG1854	S-ribosylhomocysteine lyase activity
BEK99_RS02865	COG5146	pantothenate kinase activity
BEK99_RS02875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BEK99_RS02880	COG3343	RNA polymerase activity
BEK99_RS02885	COG0504	CTP synthase activity
BEK99_RS02895	COG0191	fructose-bisphosphate aldolase activity
BEK99_RS02900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BEK99_RS02910	COG1012	belongs to the aldehyde dehydrogenase family
BEK99_RS02915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BEK99_RS02920	COG0254	rRNA binding
BEK99_RS02930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BEK99_RS02935	COG2890	protein-(glutamine-N5) methyltransferase activity
BEK99_RS02940	COG0009	L-threonylcarbamoyladenylate synthase
BEK99_RS02945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BEK99_RS02950	COG4475	Protein of unknown function (DUF436)
BEK99_RS02955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BEK99_RS02960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BEK99_RS02965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BEK99_RS02975	COG0356	it plays a direct role in the translocation of protons across the membrane
BEK99_RS02980	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BEK99_RS02985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BEK99_RS02990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BEK99_RS03000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BEK99_RS03005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BEK99_RS03010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BEK99_RS03020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BEK99_RS03030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BEK99_RS03040	COG0629	single-stranded DNA binding
BEK99_RS03045	COG1388	LysM domain
BEK99_RS03050	COG1388	LysM domain
BEK99_RS03060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BEK99_RS03070	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BEK99_RS03075	COG0352	thiamine-phosphate diphosphorylase activity
BEK99_RS03080	COG0706	membrane insertase activity
BEK99_RS03090	COG1418	mRNA catabolic process
BEK99_RS03100	COG1937	Protein conserved in bacteria
BEK99_RS03115	COG2217	Heavy metal translocating P-type atpase
BEK99_RS03120	COG0772	Belongs to the SEDS family
BEK99_RS03125	COG1181	Belongs to the D-alanine--D-alanine ligase family
BEK99_RS03130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BEK99_RS03150	COG3402	PFAM membrane-flanked domain
BEK99_RS03155	COG0736	holo-[acyl-carrier-protein] synthase activity
BEK99_RS03160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BEK99_RS03175	COG2208	phosphoserine phosphatase activity
BEK99_RS03190	COG1191	sigma factor activity
BEK99_RS03195	COG2183	response to ionizing radiation
BEK99_RS03235	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BEK99_RS03240	COG0473	3-isopropylmalate dehydrogenase activity
BEK99_RS03245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BEK99_RS03250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BEK99_RS03255	COG0440	acetolactate synthase activity
BEK99_RS03260	COG0028	Belongs to the TPP enzyme family
BEK99_RS03265	COG0129	dihydroxy-acid dehydratase activity
BEK99_RS03270	COG0802	atpase or kinase
BEK99_RS03275	COG1214	PFAM Peptidase M22, glycoprotease
BEK99_RS03280	COG0456	acetyltransferase
BEK99_RS03285	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BEK99_RS03290	COG0488	(ABC) transporter
BEK99_RS03295	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BEK99_RS03300	COG0425	Belongs to the sulfur carrier protein TusA family
BEK99_RS03305	COG2391	methyltransferase activity
BEK99_RS03310	COG1621	beta-fructofuranosidase activity
BEK99_RS03315	COG3279	Response regulator of the LytR AlgR family
BEK99_RS03330	COG4512	PFAM Accessory gene regulator B
BEK99_RS03355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BEK99_RS03360	COG0459	protein refolding
BEK99_RS03395	COG1725	Transcriptional regulator
BEK99_RS03400	COG1131	(ABC) transporter
BEK99_RS03410	COG1131	(ABC) transporter
BEK99_RS03455	COG2706	6-phosphogluconolactonase activity
BEK99_RS03470	COG1335	isochorismatase
BEK99_RS03475	COG1227	inorganic diphosphatase activity
BEK99_RS03480	COG1012	belongs to the aldehyde dehydrogenase family
BEK99_RS03490	COG0077	Prephenate dehydratase
BEK99_RS03500	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BEK99_RS03505	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BEK99_RS03510	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BEK99_RS03520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BEK99_RS03525	COG4496	protein, YerC YecD
BEK99_RS03530	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BEK99_RS03540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BEK99_RS03545	COG4851	CamS sex pheromone cAM373 precursor
BEK99_RS03555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEK99_RS03560	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BEK99_RS03570	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BEK99_RS03575	COG1597	lipid kinase activity
BEK99_RS03590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BEK99_RS03635	COG2197	response regulator
BEK99_RS03640	COG0288	reversible hydration of carbon dioxide
BEK99_RS03645	COG1295	ribonuclease BN
BEK99_RS03660	COG4840	Belongs to the UPF0435 family
BEK99_RS03665	COG2309	aminopeptidase activity
BEK99_RS03670	COG1607	acyl-coa hydrolase
BEK99_RS03675	COG0535	radical SAM domain protein
BEK99_RS03685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BEK99_RS03690	COG2137	regulation of response to DNA damage stimulus
BEK99_RS03710	COG1988	membrane-bound metal-dependent
BEK99_RS03720	COG3557	Belongs to the UPF0374 family
BEK99_RS03730	COG4129	membrane
BEK99_RS03740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BEK99_RS03750	COG0735	belongs to the Fur family
BEK99_RS03900	COG0765	amino acid transport
BEK99_RS03905	COG1126	abc transporter atp-binding protein
BEK99_RS03910	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BEK99_RS03920	COG0363	glucosamine-6-phosphate deaminase activity
BEK99_RS03930	COG0114	fumarate hydratase activity
BEK99_RS03935	COG0564	pseudouridine synthase activity
BEK99_RS03945	COG2197	response regulator
BEK99_RS03950	COG1301	dicarboxylic acid transport
BEK99_RS03960	COG4399	Belongs to the UPF0754 family
BEK99_RS03965	COG3679	Belongs to the UPF0342 family
BEK99_RS03970	COG0420	3'-5' exonuclease activity
BEK99_RS03980	COG3481	metal-dependent phosphohydrolase, HD sub domain
BEK99_RS03985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BEK99_RS04000	COG0537	adenosine 5'-monophosphoramidase activity
BEK99_RS04005	COG1131	(ABC) transporter
BEK99_RS04010	COG4473	ABC transporter
BEK99_RS04020	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BEK99_RS04025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BEK99_RS04030	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BEK99_RS04040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BEK99_RS04045	COG0157	Belongs to the NadC ModD family
BEK99_RS04060	COG1827	regulation of RNA biosynthetic process
BEK99_RS04065	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BEK99_RS04175	COG0629	single-stranded DNA binding
BEK99_RS04435	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BEK99_RS04445	COG1506	peptidase
BEK99_RS04450	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BEK99_RS04455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BEK99_RS04470	COG0656	L-ascorbic acid biosynthetic process
BEK99_RS04475	COG1397	ADP-ribosylglycohydrolase
BEK99_RS04480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BEK99_RS04495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BEK99_RS04510	COG1595	DNA-templated transcription, initiation
BEK99_RS04530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BEK99_RS04530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BEK99_RS04535	COG0307	riboflavin synthase, alpha
BEK99_RS04545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BEK99_RS04550	COG0506	proline dehydrogenase activity
BEK99_RS04555	COG2267	carboxylic ester hydrolase activity
BEK99_RS04565	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BEK99_RS04570	COG1242	4 iron, 4 sulfur cluster binding
BEK99_RS04575	COG2814	Major facilitator Superfamily
BEK99_RS04590	COG2081	HI0933 family
BEK99_RS04595	COG2244	polysaccharide biosynthetic process
BEK99_RS04600	COG1187	pseudouridine synthase activity
BEK99_RS04610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BEK99_RS04620	COG0510	thiamine kinase activity
BEK99_RS04625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BEK99_RS04630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEK99_RS04635	COG5584	Small secreted protein
BEK99_RS04640	COG1363	Peptidase, m42
BEK99_RS04645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEK99_RS04650	COG4848	Belongs to the UPF0354 family
BEK99_RS04655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEK99_RS04665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BEK99_RS04670	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BEK99_RS04680	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BEK99_RS04680	COG1605	Chorismate mutase
BEK99_RS04685	COG1609	Transcriptional regulator
BEK99_RS04695	COG0454	-acetyltransferase
BEK99_RS04705	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BEK99_RS04715	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BEK99_RS04720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BEK99_RS04725	COG0204	Acyl-transferase
BEK99_RS04740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BEK99_RS04745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BEK99_RS04750	COG1764	response to oxidative stress
BEK99_RS04755	COG0584	glycerophosphoryl diester phosphodiesterase
BEK99_RS04760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BEK99_RS04765	COG1956	GAF domain-containing protein
BEK99_RS04770	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BEK99_RS04775	COG1104	cysteine desulfurase activity
BEK99_RS04780	COG0301	tRNA thio-modification
BEK99_RS04790	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BEK99_RS04795	COG0827	DNA restriction-modification system
BEK99_RS04805	COG0589	response to stress
BEK99_RS04810	COG0686	Belongs to the AlaDH PNT family
BEK99_RS04815	COG0006	proline dipeptidase activity
BEK99_RS04820	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BEK99_RS04845	COG0281	malic enzyme
BEK99_RS04855	COG0825	malonyl-CoA metabolic process
BEK99_RS04860	COG0205	6-phosphofructokinase activity
BEK99_RS04865	COG0469	pyruvate kinase activity
BEK99_RS04870	COG1113	amino acid transport
BEK99_RS04875	COG0372	Belongs to the citrate synthase family
BEK99_RS04885	COG0745	RESPONSE REGULATOR receiver
BEK99_RS04890	COG5002	protein histidine kinase activity
BEK99_RS04915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BEK99_RS04920	COG3611	Membrane attachment protein
BEK99_RS04925	COG1484	DNA-dependent DNA replication
BEK99_RS04930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BEK99_RS04935	COG0833	amino acid
BEK99_RS04940	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BEK99_RS04945	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BEK99_RS04950	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BEK99_RS04955	COG4112	unkown
BEK99_RS04965	COG0544	peptidyl-prolyl cis-trans isomerase activity
BEK99_RS04970	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BEK99_RS04975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BEK99_RS04980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BEK99_RS04985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BEK99_RS04990	COG0181	hydroxymethylbilane synthase activity
BEK99_RS05005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BEK99_RS05010	COG3180	Ammonia monooxygenase
BEK99_RS05015	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BEK99_RS05020	COG2818	Glycosylase
BEK99_RS05025	COG0525	valine-tRNA ligase activity
BEK99_RS05030	COG0285	dihydrofolate synthase activity
BEK99_RS05040	COG2003	Belongs to the UPF0758 family
BEK99_RS05050	COG1792	Involved in formation and maintenance of cell shape
BEK99_RS05065	COG2868	ribosomal protein
BEK99_RS05070	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BEK99_RS05075	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BEK99_RS05080	COG4492	Belongs to the UPF0735 family
BEK99_RS05085	COG0632	four-way junction helicase activity
BEK99_RS05090	COG2255	four-way junction helicase activity
BEK99_RS05095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BEK99_RS05100	COG0343	queuine tRNA-ribosyltransferase activity
BEK99_RS05105	COG1862	Preprotein translocase
BEK99_RS05110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BEK99_RS05110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BEK99_RS05115	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BEK99_RS05115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BEK99_RS05120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BEK99_RS05130	COG1490	D-aminoacyl-tRNA deacylase activity
BEK99_RS05135	COG0860	N-Acetylmuramoyl-L-alanine amidase
BEK99_RS05140	COG0124	histidyl-tRNA synthetase
BEK99_RS05145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BEK99_RS05155	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BEK99_RS05165	COG1959	2 iron, 2 sulfur cluster binding
BEK99_RS05170	COG3237	CsbD-like
BEK99_RS05175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEK99_RS05180	COG1104	cysteine desulfurase activity
BEK99_RS05185	COG0482	sulfurtransferase activity
BEK99_RS05195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BEK99_RS05200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BEK99_RS05205	COG4472	Bacterial protein of unknown function (DUF965)
BEK99_RS05210	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BEK99_RS05215	COG3906	Belongs to the UPF0473 family
BEK99_RS05220	COG4122	O-methyltransferase activity
BEK99_RS05230	COG0826	peptidase U32
BEK99_RS05235	COG0572	uridine kinase
BEK99_RS05240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BEK99_RS05245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BEK99_RS05250	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BEK99_RS05255	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BEK99_RS05260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BEK99_RS05265	COG1534	Rna-binding protein
BEK99_RS05270	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BEK99_RS05275	COG1713	HD superfamily hydrolase involved in NAD metabolism
BEK99_RS05280	COG0799	negative regulation of ribosome biogenesis
BEK99_RS05285	COG2226	methyltransferase
BEK99_RS05290	COG1596	polysaccharide export
BEK99_RS05290	COG1555	photosystem II stabilization
BEK99_RS05295	COG2131	deaminase
BEK99_RS05310	COG0268	Binds directly to 16S ribosomal RNA
BEK99_RS05320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BEK99_RS05325	COG1420	regulation of RNA biosynthetic process
BEK99_RS05330	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BEK99_RS05335	COG0443	Heat shock 70 kDa protein
BEK99_RS05340	COG0484	heat shock protein binding
BEK99_RS05345	COG2264	protein methyltransferase activity
BEK99_RS05350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BEK99_RS05355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BEK99_RS05370	COG4864	UPF0365 protein
BEK99_RS05380	COG1702	phosphate starvation-inducible protein PhoH
BEK99_RS05385	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BEK99_RS05390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BEK99_RS05400	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BEK99_RS05410	COG0423	glycine-tRNA ligase activity
BEK99_RS05415	COG0517	IMP dehydrogenase activity
BEK99_RS05420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BEK99_RS05430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BEK99_RS05435	COG2384	SAM-dependent methyltransferase
BEK99_RS05445	COG0513	Belongs to the DEAD box helicase family
BEK99_RS05450	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BEK99_RS05455	COG1121	(ABC) transporter
BEK99_RS05460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BEK99_RS05475	COG0768	penicillin binding
BEK99_RS05480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BEK99_RS05490	COG4483	Protein conserved in bacteria
BEK99_RS05495	COG1940	carbohydrate kinase activity
BEK99_RS05500	COG0011	TIGRFAM Protein of
BEK99_RS05505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEK99_RS05510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BEK99_RS05540	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BEK99_RS05545	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BEK99_RS05555	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BEK99_RS05560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BEK99_RS05565	COG0095	Lipoate-protein ligase
BEK99_RS05580	COG0006	proline dipeptidase activity
BEK99_RS05585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BEK99_RS05590	COG0511	ligase activity, forming carbon-carbon bonds
BEK99_RS05595	COG0439	Biotin carboxylase
BEK99_RS05605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BEK99_RS05610	COG1570	exodeoxyribonuclease VII activity
BEK99_RS05625	COG1438	arginine binding
BEK99_RS05630	COG0497	DNA recombination
BEK99_RS05635	COG0280	phosphate acetyltransferase
BEK99_RS05640	COG3426	butyrate kinase activity
BEK99_RS05645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BEK99_RS05650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BEK99_RS05655	COG0022	dehydrogenase e1 component
BEK99_RS05660	COG0508	dehydrogenase complex catalyzes the overall conversion of
BEK99_RS05670	COG4129	membrane
BEK99_RS05680	COG2195	Cleaves the N-terminal amino acid of tripeptides
BEK99_RS05685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BEK99_RS05695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BEK99_RS05700	COG1234	tRNA 3'-trailer cleavage
BEK99_RS05720	COG0494	nUDIX hydrolase
BEK99_RS05725	COG0735	belongs to the Fur family
BEK99_RS05730	COG4974	Belongs to the 'phage' integrase family
BEK99_RS05740	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BEK99_RS05745	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BEK99_RS05750	COG1187	pseudouridine synthase activity
BEK99_RS05755	COG0745	RESPONSE REGULATOR receiver
BEK99_RS05770	COG1141	Ferredoxin
BEK99_RS05780	COG0514	ATP-dependent DNA helicase (RecQ)
BEK99_RS05785	COG1388	LysM domain
BEK99_RS05785	COG1388	LysM domain
BEK99_RS05790	COG0492	ferredoxin-NADP+ reductase activity
BEK99_RS05800	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BEK99_RS05805	COG0539	negative regulation of cytoplasmic translation
BEK99_RS05810	COG1160	GTP binding
BEK99_RS05815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BEK99_RS05830	COG2226	methyltransferase
BEK99_RS05835	COG0142	geranyltranstransferase activity
BEK99_RS05840	COG0105	UTP biosynthetic process
BEK99_RS05845	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BEK99_RS05850	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BEK99_RS05855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BEK99_RS05865	COG5582	Belongs to the UPF0302 family
BEK99_RS05870	COG4347	Protein of unknown function (DUF1405)
BEK99_RS05875	COG2738	Putative neutral zinc metallopeptidase
BEK99_RS05880	COG1694	Mazg nucleotide pyrophosphohydrolase
BEK99_RS05885	COG0438	transferase activity, transferring glycosyl groups
BEK99_RS05890	COG0617	tRNA 3'-terminal CCA addition
BEK99_RS05900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BEK99_RS05900	COG1199	ATP-dependent helicase activity
BEK99_RS05905	COG0017	Asparaginyl-tRNA synthetase
BEK99_RS05910	COG3935	DnaD domain protein
BEK99_RS05915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BEK99_RS05925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BEK99_RS05925	COG4499	WXG100 protein secretion system (Wss), protein YukC
BEK99_RS05930	COG3331	DNA recombination
BEK99_RS05940	COG4474	Belongs to the UPF0398 family
BEK99_RS05945	COG3599	regulation of cell shape
BEK99_RS05955	COG0116	Belongs to the methyltransferase superfamily
BEK99_RS05960	COG2962	Rard protein
BEK99_RS05965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BEK99_RS05970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BEK99_RS05975	COG0328	RNA-DNA hybrid ribonuclease activity
BEK99_RS05980	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BEK99_RS05985	COG1413	lyase activity
BEK99_RS06015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BEK99_RS06020	COG2190	(PTS) system
BEK99_RS06025	COG4479	Belongs to the UPF0346 family
BEK99_RS06030	COG0793	Belongs to the peptidase S41A family
BEK99_RS06040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BEK99_RS06045	COG0671	phosphoesterase, PA-phosphatase related
BEK99_RS06050	COG0745	RESPONSE REGULATOR receiver
BEK99_RS06055	COG5002	protein histidine kinase activity
BEK99_RS06060	COG0567	Dehydrogenase, E1 component
BEK99_RS06085	COG0714	Associated with various cellular activities
BEK99_RS06090	COG4548	von Willebrand factor, type A
BEK99_RS06095	COG1114	Component of the transport system for branched-chain amino acids
BEK99_RS06100	COG1597	lipid kinase activity
BEK99_RS06105	COG3853	Toxic anion resistance protein (TelA)
BEK99_RS06140	COG1473	amidohydrolase
BEK99_RS06145	COG2171	N-acyltransferase activity
BEK99_RS06150	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BEK99_RS06155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BEK99_RS06160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BEK99_RS06165	COG0527	aspartate kinase activity
BEK99_RS06170	COG0488	(ABC) transporter
BEK99_RS06175	COG2996	Protein conserved in bacteria
BEK99_RS06180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BEK99_RS06185	COG0573	inorganic phosphate transmembrane transporter activity
BEK99_RS06190	COG0581	inorganic phosphate transmembrane transporter activity
BEK99_RS06195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BEK99_RS06200	COG0704	Plays a role in the regulation of phosphate uptake
BEK99_RS06205	COG1164	Oligoendopeptidase f
BEK99_RS06245	COG2348	transferase activity, transferring amino-acyl groups
BEK99_RS06250	COG2348	transferase activity, transferring amino-acyl groups
BEK99_RS06255	COG0159	tryptophan synthase activity
BEK99_RS06265	COG0135	phosphoribosylanthranilate isomerase activity
BEK99_RS06270	COG0134	indole-3-glycerol-phosphate synthase activity
BEK99_RS06275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BEK99_RS06285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BEK99_RS06290	COG1363	Peptidase, m42
BEK99_RS06295	COG0287	Prephenate dehydrogenase
BEK99_RS06300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BEK99_RS06340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BEK99_RS06340	COG1263	PTS System
BEK99_RS06340	COG2190	(PTS) system
BEK99_RS06345	COG3711	transcriptional antiterminator
BEK99_RS06350	COG1115	amino acid carrier protein
BEK99_RS06355	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BEK99_RS06360	COG0187	DNA topoisomerase II activity
BEK99_RS06365	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BEK99_RS06370	COG4841	protein insertion into membrane
BEK99_RS06375	COG0824	Thioesterase
BEK99_RS06380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BEK99_RS06385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BEK99_RS06390	COG1970	mechanosensitive ion channel activity
BEK99_RS06400	COG0420	3'-5' exonuclease activity
BEK99_RS06405	COG4846	Membrane protein involved in cytochrome C biogenesis
BEK99_RS06410	COG3763	UPF0154 protein
BEK99_RS06415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BEK99_RS06420	COG4224	UPF0291 protein
BEK99_RS06430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BEK99_RS06435	COG2340	Cysteine-rich secretory protein family
BEK99_RS06440	COG0516	GMP reductase activity
BEK99_RS06445	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BEK99_RS06455	COG0833	amino acid
BEK99_RS06465	COG0561	phosphatase activity
BEK99_RS06470	COG0083	homoserine kinase activity
BEK99_RS06475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BEK99_RS06480	COG0460	homoserine dehydrogenase
BEK99_RS06485	COG0527	aspartate kinase activity
BEK99_RS06510	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BEK99_RS06515	COG1525	nuclease
BEK99_RS06525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BEK99_RS06535	COG0789	Transcriptional regulator
BEK99_RS06545	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BEK99_RS06550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BEK99_RS06560	COG1923	regulation of RNA biosynthetic process
BEK99_RS06565	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BEK99_RS06570	COG2267	carboxylic ester hydrolase activity
BEK99_RS06575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BEK99_RS06580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BEK99_RS06585	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BEK99_RS06595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BEK99_RS06600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BEK99_RS06605	COG0584	glycerophosphoryl diester phosphodiesterase
BEK99_RS06615	COG4550	Control of competence regulator ComK, YlbF/YmcA
BEK99_RS06625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BEK99_RS06640	COG0444	Belongs to the ABC transporter superfamily
BEK99_RS06660	COG1013	pyruvate-flavodoxin oxidoreductase activity
BEK99_RS06665	COG0674	pyruvate-flavodoxin oxidoreductase activity
BEK99_RS06665	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BEK99_RS06670	COG1692	metallophosphoesterase
BEK99_RS06680	COG0583	DNA-binding transcription factor activity
BEK99_RS06690	COG1418	mRNA catabolic process
BEK99_RS06695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BEK99_RS06700	COG1546	Belongs to the CinA family
BEK99_RS06700	COG1058	Belongs to the CinA family
BEK99_RS06720	COG0300	oxidoreductase activity
BEK99_RS06725	COG0612	Peptidase, M16
BEK99_RS06730	COG0612	Peptidase, M16
BEK99_RS06735	COG2188	Transcriptional regulator
BEK99_RS06745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BEK99_RS06750	COG1185	polyribonucleotide nucleotidyltransferase activity
BEK99_RS06755	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BEK99_RS06760	COG0196	riboflavin kinase activity
BEK99_RS06765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BEK99_RS06770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BEK99_RS06795	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BEK99_RS06800	COG1358	cellular component organization or biogenesis
BEK99_RS06805	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BEK99_RS06810	COG0195	Participates in both transcription termination and antitermination
BEK99_RS06815	COG0779	Required for maturation of 30S ribosomal subunits
BEK99_RS06820	COG2176	DNA-directed DNA polymerase activity
BEK99_RS06825	COG0442	prolyl-tRNA aminoacylation
BEK99_RS06835	COG4589	Belongs to the CDS family
BEK99_RS06845	COG0233	cytoplasmic translational termination
BEK99_RS06850	COG0528	UMP kinase activity
BEK99_RS06855	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BEK99_RS06860	COG0052	Belongs to the universal ribosomal protein uS2 family
BEK99_RS06865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BEK99_RS06870	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BEK99_RS06875	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BEK99_RS06880	COG4974	Belongs to the 'phage' integrase family
BEK99_RS06885	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BEK99_RS06890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BEK99_RS06900	COG0045	succinate-CoA ligase (ADP-forming) activity
BEK99_RS06905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BEK99_RS06930	COG4149	molybdate abc transporter
BEK99_RS06940	COG1349	DNA-binding transcription factor activity
BEK99_RS06960	COG4485	Bacterial membrane protein, YfhO
BEK99_RS06985	COG0335	large ribosomal subunit rRNA binding
BEK99_RS06990	COG0336	Belongs to the RNA methyltransferase TrmD family
BEK99_RS06995	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BEK99_RS07000	COG0228	four-way junction DNA binding
BEK99_RS07010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BEK99_RS07015	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BEK99_RS07020	COG0552	protein localization to endoplasmic reticulum
BEK99_RS07025	COG1196	nuclear chromosome segregation
BEK99_RS07030	COG0571	ribonuclease III activity
BEK99_RS07035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BEK99_RS07050	COG0416	fatty acid biosynthetic process
BEK99_RS07055	COG1349	DNA-binding transcription factor activity
BEK99_RS07065	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BEK99_RS07075	COG1760	l-serine dehydratase
BEK99_RS07080	COG1461	Dihydroxyacetone kinase
BEK99_RS07085	COG1302	Protein conserved in bacteria
BEK99_RS07090	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BEK99_RS07105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BEK99_RS07110	COG1162	GTPase activity
BEK99_RS07120	COG0631	protein serine/threonine phosphatase activity
BEK99_RS07125	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BEK99_RS07130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BEK99_RS07130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BEK99_RS07135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BEK99_RS07160	COG2910	NAD(P)H-binding
BEK99_RS07165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BEK99_RS07170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BEK99_RS07180	COG1758	RNA polymerase activity
BEK99_RS07215	COG0284	orotidine-5'-phosphate decarboxylase activity
BEK99_RS07220	COG0167	dihydroorotate dehydrogenase activity
BEK99_RS07225	COG0543	2 iron, 2 sulfur cluster binding
BEK99_RS07230	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BEK99_RS07235	COG0505	Belongs to the CarA family
BEK99_RS07245	COG0540	Belongs to the ATCase OTCase family
BEK99_RS07250	COG2233	PERMEase
BEK99_RS07255	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BEK99_RS07260	COG0564	pseudouridine synthase activity
BEK99_RS07265	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BEK99_RS07270	COG3942	CHAP domain
BEK99_RS07280	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BEK99_RS07285	COG3599	regulation of cell shape
BEK99_RS07295	COG0762	integral membrane protein
BEK99_RS07300	COG1799	cell septum assembly
BEK99_RS07305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BEK99_RS07310	COG1496	oxidoreductase activity
BEK99_RS07320	COG0849	cell division
BEK99_RS07325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BEK99_RS07330	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BEK99_RS07335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BEK99_RS07340	COG0768	penicillin binding
BEK99_RS07345	COG4839	cell division protein FtsL
BEK99_RS07350	COG0275	rRNA processing
BEK99_RS07355	COG2001	Belongs to the MraZ family
BEK99_RS07360	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BEK99_RS07365	COG0454	-acetyltransferase
BEK99_RS07370	COG1011	Hydrolase
BEK99_RS07435	COG2153	protein acetylation
BEK99_RS07465	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BEK99_RS07480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BEK99_RS07485	COG1053	succinate dehydrogenase
BEK99_RS07490	COG2009	succinate dehydrogenase
BEK99_RS07495	COG0322	excinuclease ABC activity
BEK99_RS07500	COG3118	belongs to the thioredoxin family
BEK99_RS07505	COG1193	negative regulation of DNA recombination
BEK99_RS07510	COG1796	DNA polymerase
BEK99_RS07510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BEK99_RS07525	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BEK99_RS07535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BEK99_RS07540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BEK99_RS07545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BEK99_RS07555	COG1323	Belongs to the UPF0348 family
BEK99_RS07565	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BEK99_RS07570	COG0742	ribosomal rna small subunit methyltransferase
BEK99_RS07580	COG4471	UPF0298 protein
BEK99_RS07585	COG0584	glycerophosphoryl diester phosphodiesterase
BEK99_RS07590	COG3679	Belongs to the UPF0342 family
BEK99_RS07605	COG0109	protoheme IX farnesyltransferase activity
BEK99_RS07610	COG1612	heme a metabolic process
BEK99_RS07620	COG0772	Belongs to the SEDS family
BEK99_RS07625	COG4838	Belongs to the UPF0358 family
BEK99_RS07630	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BEK99_RS07640	COG1217	gtp-binding protein TYPA
BEK99_RS07650	COG0483	inositol monophosphate 1-phosphatase activity
BEK99_RS07655	COG4493	Belongs to the UPF0637 family
BEK99_RS07660	COG1914	H( )-stimulated, divalent metal cation uptake system
BEK99_RS07680	COG1177	transmembrane transport
BEK99_RS07685	COG1176	ABC-type spermidine putrescine transport system, permease component I
BEK99_RS07690	COG3842	ATPase activity
BEK99_RS07700	COG4476	Belongs to the UPF0223 family
BEK99_RS07715	COG0022	dehydrogenase e1 component
BEK99_RS07730	COG0242	peptide deformylase activity
BEK99_RS07740	COG5503	Protein of unknown function (DUF1447)
BEK99_RS07750	COG1733	regulation of RNA biosynthetic process
BEK99_RS07755	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BEK99_RS07765	COG0569	domain protein
BEK99_RS07770	COG1294	oxidase, subunit
BEK99_RS07775	COG1271	oxidase subunit
BEK99_RS07785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BEK99_RS07820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BEK99_RS07830	COG0151	Belongs to the GarS family
BEK99_RS07835	COG0138	bifunctional purine biosynthesis protein purh
BEK99_RS07840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BEK99_RS07845	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BEK99_RS07850	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BEK99_RS07855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BEK99_RS07870	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BEK99_RS07875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BEK99_RS07880	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BEK99_RS07885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BEK99_RS07890	COG1363	Peptidase, m42
BEK99_RS07895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BEK99_RS07895	COG1017	nitric oxide dioxygenase activity
BEK99_RS07915	COG1845	cytochrome c oxidase, subunit III
BEK99_RS07920	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BEK99_RS07930	COG1349	DNA-binding transcription factor activity
BEK99_RS07940	COG0698	ribose 5-phosphate isomerase
BEK99_RS07960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BEK99_RS07965	COG2723	6-phospho-beta-galactosidase activity
BEK99_RS07970	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BEK99_RS07970	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BEK99_RS07975	COG1447	Phosphotransferase system cellobiose-specific component IIA
BEK99_RS07990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BEK99_RS07995	COG1316	TRANSCRIPTIONal
BEK99_RS08025	COG0436	Aminotransferase
BEK99_RS08030	COG1846	Transcriptional regulator
BEK99_RS08035	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BEK99_RS08045	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BEK99_RS08050	COG1169	isochorismate synthase
BEK99_RS08055	COG1575	Belongs to the MenA family. Type 1 subfamily
BEK99_RS08065	COG2314	TM2 domain
BEK99_RS08080	COG4873	Protein conserved in bacteria
BEK99_RS08110	COG3177	Filamentation induced by cAMP protein fic
BEK99_RS08125	COG2267	carboxylic ester hydrolase activity
BEK99_RS08135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BEK99_RS08140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BEK99_RS08145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BEK99_RS08150	COG0131	Imidazoleglycerol-phosphate dehydratase
BEK99_RS08160	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BEK99_RS08165	COG0107	imidazoleglycerol-phosphate synthase activity
BEK99_RS08185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BEK99_RS08195	COG0861	Integral membrane protein TerC family
BEK99_RS08200	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BEK99_RS08210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BEK99_RS08215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BEK99_RS08220	COG2814	Major facilitator Superfamily
BEK99_RS08230	COG2382	esterase
BEK99_RS08235	COG1115	amino acid carrier protein
BEK99_RS08240	COG0628	permease
BEK99_RS08245	COG2814	Major facilitator Superfamily
BEK99_RS08255	COG0475	glutathione-regulated potassium exporter activity
BEK99_RS08255	COG0569	domain protein
BEK99_RS08260	COG2239	Acts as a magnesium transporter
BEK99_RS08265	COG0564	pseudouridine synthase activity
BEK99_RS08270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BEK99_RS08275	COG2357	RelA SpoT domain protein
BEK99_RS08285	COG4116	CYTH
BEK99_RS08290	COG2346	COG2346, Truncated hemoglobins
BEK99_RS08310	COG1164	Oligoendopeptidase f
BEK99_RS08315	COG4862	establishment of competence for transformation
BEK99_RS08320	COG1393	Belongs to the ArsC family
BEK99_RS08330	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BEK99_RS08335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEK99_RS08340	COG4166	transmembrane transport
BEK99_RS08345	COG4608	Belongs to the ABC transporter superfamily
BEK99_RS08350	COG0444	Belongs to the ABC transporter superfamily
BEK99_RS08355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BEK99_RS08360	COG0601	transmembrane transport
BEK99_RS08380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BEK99_RS08390	COG0542	response to heat
BEK99_RS08400	COG2151	metal-sulfur cluster biosynthetic enzyme
BEK99_RS08405	COG0561	phosphatase activity
BEK99_RS08410	COG0446	pyridine nucleotide-disulphide oxidoreductase
BEK99_RS08420	COG0179	Fumarylacetoacetate (FAA) hydrolase
BEK99_RS08425	COG1074	ATP-dependent DNA helicase activity
BEK99_RS08430	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BEK99_RS08445	COG0398	Pfam SNARE associated Golgi protein
BEK99_RS08455	COG0137	argininosuccinate synthase activity
BEK99_RS08460	COG0165	Argininosuccinate lyase
BEK99_RS08475	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BEK99_RS08480	COG1012	belongs to the aldehyde dehydrogenase family
BEK99_RS08485	COG1902	pentaerythritol trinitrate reductase activity
BEK99_RS08490	COG1098	S1 RNA binding domain
BEK99_RS08495	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BEK99_RS08505	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BEK99_RS08515	COG2111	Na H antiporter
BEK99_RS08515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BEK99_RS08520	COG2111	Na H antiporter
BEK99_RS08525	COG1006	Multisubunit Na H antiporter MnhC subunit
BEK99_RS08530	COG0651	ATP synthesis coupled electron transport
BEK99_RS08535	COG1863	multisubunit Na H antiporter MnhE subunit
BEK99_RS08540	COG2212	antiporter activity
BEK99_RS08555	COG2050	protein possibly involved in aromatic compounds catabolism
BEK99_RS08560	COG2056	Na+-H+ antiporter family
BEK99_RS08565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BEK99_RS08570	COG1252	NADH dehydrogenase
BEK99_RS08575	COG0316	Belongs to the HesB IscA family
BEK99_RS08580	COG4844	belongs to the
BEK99_RS08585	COG1252	NADH dehydrogenase
BEK99_RS08590	COG0519	Catalyzes the synthesis of GMP from XMP
BEK99_RS08595	COG4837	Protein of unknown function (DUF1462)
BEK99_RS08600	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BEK99_RS08605	COG0789	Transcriptional regulator
BEK99_RS08610	COG2217	Heavy metal translocating P-type atpase
BEK99_RS08615	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BEK99_RS08620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BEK99_RS08625	COG1696	Membrane protein involved in D-alanine export
BEK99_RS08640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BEK99_RS08645	COG0647	UMP catabolic process
BEK99_RS08650	COG2445	Protein of unknown function DUF86
BEK99_RS08660	COG4470	Protein conserved in bacteria
BEK99_RS08665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BEK99_RS08675	COG0730	response to heat
BEK99_RS08680	COG1801	Protein of unknown function DUF72
BEK99_RS08690	COG4536	flavin adenine dinucleotide binding
BEK99_RS08710	COG1388	LysM domain
BEK99_RS08710	COG5632	N-Acetylmuramoyl-L-alanine amidase
BEK99_RS08735	COG4632	Exopolysaccharide biosynthesis protein
BEK99_RS08735	COG5434	Belongs to the glycosyl hydrolase 28 family
BEK99_RS08800	COG0740	serine-type endopeptidase activity
BEK99_RS08845	COG0756	dUTP diphosphatase activity
BEK99_RS08895	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BEK99_RS08960	COG3617	BRO family, N-terminal domain
BEK99_RS09000	COG4974	Belongs to the 'phage' integrase family
BEK99_RS09005	COG0719	Fe-S assembly protein
BEK99_RS09010	COG0822	iron-sulfur transferase activity
BEK99_RS09015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BEK99_RS09020	COG0719	Fe-S assembly protein
BEK99_RS09025	COG0396	ATPase activity
BEK99_RS09030	COG1464	Belongs to the NlpA lipoprotein family
BEK99_RS09035	COG2011	ABC-type metal ion transport system permease component
BEK99_RS09040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BEK99_RS09050	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BEK99_RS09055	COG0509	glycine decarboxylation via glycine cleavage system
BEK99_RS09060	COG1393	Belongs to the ArsC family
BEK99_RS09065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BEK99_RS09075	COG0710	3-dehydroquinate dehydratase activity
BEK99_RS09105	COG1704	LemA family
BEK99_RS09110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BEK99_RS09130	COG1278	Cold shock
BEK99_RS09145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BEK99_RS09155	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BEK99_RS09160	COG0557	exoribonuclease II activity
BEK99_RS09165	COG1647	Serine aminopeptidase, S33
BEK99_RS09170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BEK99_RS09180	COG0148	phosphopyruvate hydratase activity
BEK99_RS09185	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BEK99_RS09190	COG0149	triose-phosphate isomerase activity
BEK99_RS09195	COG0126	phosphoglycerate kinase activity
BEK99_RS09200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BEK99_RS09225	COG0740	serine-type endopeptidase activity
BEK99_RS09235	COG1114	Component of the transport system for branched-chain amino acids
BEK99_RS09240	COG2814	Major facilitator Superfamily
BEK99_RS09245	COG1481	regulation of sporulation
BEK99_RS09250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BEK99_RS09255	COG1660	Displays ATPase and GTPase activities
BEK99_RS09270	COG0110	maltose O-acetyltransferase activity
BEK99_RS09275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BEK99_RS09305	COG3942	CHAP domain
BEK99_RS09310	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BEK99_RS09315	COG0653	protein targeting
BEK99_RS09320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BEK99_RS09330	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BEK99_RS09340	COG1739	Uncharacterized protein family UPF0029
BEK99_RS09345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BEK99_RS09350	COG2199	diguanylate cyclase activity
BEK99_RS09365	COG2195	Cleaves the N-terminal amino acid of tripeptides
BEK99_RS09370	COG1929	Belongs to the glycerate kinase type-1 family
BEK99_RS09405	COG4607	ABC-type enterochelin transport system periplasmic component
BEK99_RS09410	COG4604	ABC transporter, ATP-binding protein
BEK99_RS09415	COG4605	iron ion homeostasis
BEK99_RS09420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEK99_RS09425	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BEK99_RS09430	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BEK99_RS09435	COG1780	Probably involved in ribonucleotide reductase function
BEK99_RS09440	COG0697	spore germination
BEK99_RS09445	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BEK99_RS09450	COG3104	oligopeptide transport
BEK99_RS09455	COG3104	oligopeptide transport
BEK99_RS09465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BEK99_RS09470	COG1174	glycine betaine transport
BEK99_RS09480	COG0514	ATP-dependent DNA helicase (RecQ)
BEK99_RS09485	COG0488	(ABC) transporter
BEK99_RS09490	COG1368	sulfuric ester hydrolase activity
BEK99_RS09500	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BEK99_RS09515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BEK99_RS09515	COG0512	Glutamine amidotransferase of anthranilate synthase
BEK99_RS09520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BEK99_RS09525	COG0720	synthase
BEK99_RS09530	COG0602	queuosine metabolic process
BEK99_RS09545	COG0656	L-ascorbic acid biosynthetic process
BEK99_RS09550	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BEK99_RS09575	COG1253	flavin adenine dinucleotide binding
BEK99_RS09580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BEK99_RS09580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BEK99_RS09580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BEK99_RS09585	COG1105	Belongs to the carbohydrate kinase PfkB family
BEK99_RS09590	COG1349	DNA-binding transcription factor activity
BEK99_RS09595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BEK99_RS09610	COG1464	Belongs to the NlpA lipoprotein family
BEK99_RS09630	COG0471	metal ion transport
BEK99_RS09635	COG0039	L-malate dehydrogenase activity
BEK99_RS09640	COG0586	Pfam SNARE associated Golgi protein
BEK99_RS09650	COG4989	oxidoreductase activity
BEK99_RS09655	COG0523	cobalamin synthesis protein
BEK99_RS09665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BEK99_RS09670	COG4988	ABC transporter
BEK99_RS09675	COG1968	undecaprenyl-diphosphatase activity
BEK99_RS09685	COG1671	Belongs to the UPF0178 family
BEK99_RS09715	COG2839	Protein conserved in bacteria
BEK99_RS09720	COG2814	Major facilitator Superfamily
BEK99_RS09725	COG0583	DNA-binding transcription factor activity
BEK99_RS09740	COG0217	transcriptional regulatory protein
BEK99_RS09765	COG3942	CHAP domain
BEK99_RS09765	COG1388	LysM domain
BEK99_RS09770	COG1733	regulation of RNA biosynthetic process
BEK99_RS09780	COG0656	L-ascorbic acid biosynthetic process
BEK99_RS09785	COG0306	phosphate transporter
BEK99_RS09790	COG1392	Phosphate transport regulator
BEK99_RS09805	COG2205	protein histidine kinase activity
BEK99_RS09810	COG0745	RESPONSE REGULATOR receiver
BEK99_RS09825	COG3949	Membrane
BEK99_RS09835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEK99_RS09840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BEK99_RS09845	COG1120	ATPase activity
BEK99_RS09850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BEK99_RS09855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BEK99_RS09860	COG1132	(ABC) transporter
BEK99_RS09865	COG1686	Belongs to the peptidase S11 family
BEK99_RS09870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BEK99_RS09880	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BEK99_RS09885	COG1682	transport, permease protein
BEK99_RS09895	COG5609	conserved protein (DUF2294)
BEK99_RS09900	COG3949	Membrane
BEK99_RS09910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BEK99_RS09915	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BEK99_RS09920	COG0110	maltose O-acetyltransferase activity
BEK99_RS09930	COG1247	-acetyltransferase
BEK99_RS09935	COG0671	phosphoesterase, PA-phosphatase related
BEK99_RS09945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BEK99_RS09950	COG0803	Belongs to the bacterial solute-binding protein 9 family
BEK99_RS09955	COG0025	NhaP-type Na H and K H
BEK99_RS10005	COG0546	phosphoglycolate phosphatase activity
BEK99_RS10010	COG4139	cobalamin transport
BEK99_RS10015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BEK99_RS10020	COG0018	arginyl-trna synthetase
BEK99_RS10030	COG1473	amidohydrolase
BEK99_RS10035	COG4115	mRNA cleavage
BEK99_RS10055	COG1279	arginine transmembrane transporter activity
BEK99_RS10065	COG1078	dGTPase activity
BEK99_RS10070	COG0519	Catalyzes the synthesis of GMP from XMP
BEK99_RS10085	COG4844	belongs to the
BEK99_RS10105	COG0095	Lipoate-protein ligase
BEK99_RS10110	COG0280	phosphate acetyltransferase
BEK99_RS10115	COG3253	May function as heme-dependent peroxidase
BEK99_RS10120	COG2966	Psort location CytoplasmicMembrane, score
BEK99_RS10135	COG0586	Pfam SNARE associated Golgi protein
BEK99_RS10140	COG0531	amino acid
BEK99_RS10145	COG2363	Small membrane protein
BEK99_RS10155	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BEK99_RS10165	COG0477	Major facilitator Superfamily
BEK99_RS10170	COG1469	GTP cyclohydrolase I activity
BEK99_RS10175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BEK99_RS10180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BEK99_RS10185	COG0363	glucosamine-6-phosphate deaminase activity
BEK99_RS10190	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BEK99_RS10195	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BEK99_RS10200	COG0431	NADPH-dependent FMN reductase
BEK99_RS10205	COG0561	phosphatase activity
BEK99_RS10215	COG1428	Deoxynucleoside kinase
BEK99_RS10220	COG1428	Deoxynucleoside kinase
BEK99_RS10225	COG0561	phosphatase activity
BEK99_RS10235	COG0546	phosphoglycolate phosphatase activity
BEK99_RS10240	COG2832	Protein of unknown function (DUF454)
BEK99_RS10245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BEK99_RS10250	COG1619	proteins homologs of microcin C7 resistance protein MccF
BEK99_RS10270	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BEK99_RS10280	COG1473	amidohydrolase
BEK99_RS10285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BEK99_RS10290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BEK99_RS10295	COG0049	tRNA binding
BEK99_RS10300	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BEK99_RS10315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BEK99_RS10320	COG0085	RNA polymerase activity
BEK99_RS10325	COG2813	Specifically methylates the guanine in position
BEK99_RS10335	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BEK99_RS10340	COG0081	regulation of translation
BEK99_RS10345	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BEK99_RS10350	COG0250	Participates in transcription elongation, termination and antitermination
BEK99_RS10355	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BEK99_RS10370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BEK99_RS10375	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BEK99_RS10380	COG0215	cysteine-tRNA ligase activity
BEK99_RS10385	COG1045	serine acetyltransferase
BEK99_RS10390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BEK99_RS10395	COG4956	integral membrane protein (PIN domain superfamily)
BEK99_RS10400	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BEK99_RS10405	COG0542	response to heat
BEK99_RS10410	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BEK99_RS10415	COG3880	PFAM UvrB UvrC protein
BEK99_RS10425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BEK99_RS10440	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BEK99_RS10445	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BEK99_RS10460	COG2814	Major facilitator Superfamily
BEK99_RS10545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BEK99_RS10550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BEK99_RS10555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BEK99_RS10560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BEK99_RS10575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BEK99_RS10580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BEK99_RS10595	COG1098	S1 RNA binding domain
BEK99_RS10605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BEK99_RS10610	COG3956	TIGRFAM MazG family protein
BEK99_RS10615	COG2244	polysaccharide biosynthetic process
BEK99_RS10620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BEK99_RS10625	COG0193	aminoacyl-tRNA hydrolase activity
BEK99_RS10630	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BEK99_RS10640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BEK99_RS10645	COG2088	sporulation resulting in formation of a cellular spore
BEK99_RS10650	COG0251	oxidation-reduction process
BEK99_RS10655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BEK99_RS10665	COG4466	Protein conserved in bacteria
BEK99_RS10670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BEK99_RS10675	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BEK99_RS10680	COG0084	hydrolase, TatD family'
BEK99_RS10685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEK99_RS10685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BEK99_RS10730	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BEK99_RS10735	COG2827	Endonuclease containing a URI domain
BEK99_RS10750	COG1774	PSP1 C-terminal conserved region
BEK99_RS10760	COG3870	Protein conserved in bacteria
BEK99_RS10770	COG1982	Orn Lys Arg decarboxylase major
BEK99_RS10790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BEK99_RS10795	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BEK99_RS10800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BEK99_RS10815	COG2814	Major facilitator Superfamily
BEK99_RS10820	COG0583	DNA-binding transcription factor activity
BEK99_RS10835	COG0640	Transcriptional regulator
BEK99_RS10840	COG2188	Transcriptional regulator
BEK99_RS10845	COG0366	Alpha amylase catalytic
BEK99_RS10855	COG0346	lactoylglutathione lyase activity
BEK99_RS10865	COG0493	'glutamate synthase
BEK99_RS10870	COG0067	glutamate synthase
BEK99_RS10870	COG0070	glutamate synthase
BEK99_RS10870	COG0069	glutamate synthase activity
BEK99_RS10875	COG0583	DNA-binding transcription factor activity
BEK99_RS10905	COG4841	protein insertion into membrane
BEK99_RS10910	COG0494	nUDIX hydrolase
BEK99_RS10915	COG4841	protein insertion into membrane
BEK99_RS10925	COG0737	Belongs to the 5'-nucleotidase family
BEK99_RS10940	COG3246	L-lysine catabolic process to acetate
BEK99_RS10945	COG1250	3-hydroxyacyl-CoA dehydrogenase
BEK99_RS10955	COG1279	arginine transmembrane transporter activity
BEK99_RS10960	COG0626	cystathionine gamma-synthase activity
BEK99_RS10965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BEK99_RS10970	COG0733	neurotransmitter:sodium symporter activity
BEK99_RS10980	COG1647	Serine aminopeptidase, S33
BEK99_RS11025	COG0346	lactoylglutathione lyase activity
BEK99_RS11040	COG1695	Transcriptional regulator
BEK99_RS11045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BEK99_RS11070	COG0529	Catalyzes the synthesis of activated sulfate
BEK99_RS11075	COG2046	Belongs to the sulfate adenylyltransferase family
BEK99_RS11080	COG0730	response to heat
BEK99_RS11085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BEK99_RS11095	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BEK99_RS11100	COG0175	sulfate reduction
BEK99_RS11110	COG1216	Glycosyl transferase, family 2
BEK99_RS11130	COG2514	catechol 2,3-dioxygenase activity
BEK99_RS11135	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BEK99_RS11135	COG0519	Catalyzes the synthesis of GMP from XMP
BEK99_RS11140	COG0516	GMP reductase activity
BEK99_RS11140	COG0517	IMP dehydrogenase activity
BEK99_RS11145	COG2233	PERMEase
BEK99_RS11150	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BEK99_RS11170	COG1823	symporter activity
BEK99_RS11175	COG0778	Nitroreductase
BEK99_RS11185	COG0450	alkyl hydroperoxide reductase
BEK99_RS11190	COG3634	alkyl hydroperoxide reductase activity
BEK99_RS11210	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BEK99_RS11215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BEK99_RS11240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BEK99_RS11250	COG0360	Binds together with S18 to 16S ribosomal RNA
BEK99_RS11270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BEK99_RS11295	COG0012	GTP binding
BEK99_RS11300	COG4481	Protein conserved in bacteria
BEK99_RS11305	COG0668	transmembrane transport
BEK99_RS11310	COG1475	DNA binding
BEK99_RS11315	COG0626	cystathionine gamma-synthase activity
BEK99_RS11320	COG0646	methionine synthase
BEK99_RS11320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BEK99_RS11335	COG0436	Aminotransferase
BEK99_RS11350	COG1475	DNA binding
BEK99_RS11355	COG0357	Ribosomal RNA small subunit methyltransferase G
BEK99_RS11360	COG0445	tRNA wobble uridine modification
BEK99_RS11365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BEK99_RS11370	COG0594	ribonuclease P activity
BEK99_RS11380	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BEK99_RS11385	COG0592	DNA-directed DNA polymerase activity
BEK99_RS11395	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BEK99_RS11400	COG0187	DNA topoisomerase II activity
BEK99_RS11410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BEK99_RS11425	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BEK99_RS11440	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BEK99_RS11445	COG0359	binds to the 23S rRNA
BEK99_RS11450	COG0305	Participates in initiation and elongation during chromosome replication
BEK99_RS11475	COG0745	RESPONSE REGULATOR receiver
BEK99_RS11485	COG4863	YycH protein
BEK99_RS11495	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BEK99_RS11500	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BEK99_RS11510	COG0640	Transcriptional regulator
BEK99_RS11515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BEK99_RS11535	COG0640	Transcriptional regulator
BEK99_RS11555	COG2003	Belongs to the UPF0758 family
BEK99_RS11615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BEK99_RS11620	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BEK99_RS11625	COG0022	dehydrogenase e1 component
BEK99_RS11630	COG0508	dehydrogenase complex catalyzes the overall conversion of
BEK99_RS11635	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BEK99_RS11690	COG2003	Belongs to the UPF0758 family
BEK99_RS11715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BEK99_RS11725	COG2217	Heavy metal translocating P-type atpase
BEK99_RS11730	COG2217	Heavy metal translocating P-type atpase
BEK99_RS11735	COG1388	LysM domain
BEK99_RS11745	COG1937	Protein conserved in bacteria
BEK99_RS11750	COG2210	Belongs to the sulfur carrier protein TusA family
BEK99_RS11755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BEK99_RS11765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BEK99_RS11770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BEK99_RS11780	COG0789	Transcriptional regulator
BEK99_RS11790	COG0702	epimerase
BEK99_RS11795	COG2130	NADP-dependent
BEK99_RS11810	COG0702	epimerase
BEK99_RS11815	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BEK99_RS11850	COG0415	Belongs to the DNA photolyase family
BEK99_RS11870	COG0477	Major facilitator Superfamily
BEK99_RS11880	COG0076	glutamate decarboxylase activity
BEK99_RS11895	COG2814	Major facilitator Superfamily
BEK99_RS11905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BEK99_RS11905	COG3711	transcriptional antiterminator
BEK99_RS11910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BEK99_RS11910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BEK99_RS11910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BEK99_RS11915	COG1482	cell wall glycoprotein biosynthetic process
BEK99_RS11925	COG0640	Transcriptional regulator
BEK99_RS11960	COG1705	Flagellar rod assembly protein muramidase FlgJ
BEK99_RS11960	COG3942	CHAP domain
BEK99_RS12020	COG1136	(ABC) transporter
BEK99_RS12045	COG1609	Transcriptional regulator
BEK99_RS12055	COG1869	D-ribose catabolic process
BEK99_RS12070	COG0183	Belongs to the thiolase family
BEK99_RS12080	COG1960	acyl-CoA dehydrogenase activity
BEK99_RS12085	COG0318	PFAM AMP-dependent synthetase and ligase
BEK99_RS12105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BEK99_RS12140	COG0598	Magnesium transport protein CorA
BEK99_RS12150	COG0363	glucosamine-6-phosphate deaminase activity
BEK99_RS12155	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BEK99_RS12160	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BEK99_RS12160	COG0517	IMP dehydrogenase activity
BEK99_RS12170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BEK99_RS12175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEK99_RS12195	COG2226	methyltransferase
BEK99_RS12210	COG0778	Nitroreductase
BEK99_RS12245	COG1012	belongs to the aldehyde dehydrogenase family
BEK99_RS12255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BEK99_RS12260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BEK99_RS12285	COG1028	Short-chain dehydrogenase reductase Sdr
BEK99_RS12295	COG1012	belongs to the aldehyde dehydrogenase family
BEK99_RS12305	COG2851	Citrate transporter
BEK99_RS12325	COG1472	Belongs to the glycosyl hydrolase 3 family
BEK99_RS12335	COG0730	response to heat
BEK99_RS12350	COG0753	catalase activity
BEK99_RS12355	COG1063	alcohol dehydrogenase
BEK99_RS12370	COG1902	pentaerythritol trinitrate reductase activity
BEK99_RS12370	COG0446	pyridine nucleotide-disulphide oxidoreductase
BEK99_RS12375	COG0640	Transcriptional regulator
BEK99_RS12385	COG4640	response to antibiotic
BEK99_RS12405	COG1401	restriction endodeoxyribonuclease activity
BEK99_RS12430	COG3732	PTS system glucitol sorbitol-specific
BEK99_RS12435	COG3730	PTS system glucitol sorbitol-specific
BEK99_RS12460	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BEK99_RS12495	COG1966	Carbon starvation protein
BEK99_RS12545	COG2388	GCN5-related N-acetyl-transferase
BEK99_RS12550	COG0346	lactoylglutathione lyase activity
BEK99_RS12560	COG0789	Transcriptional regulator
BEK99_RS12570	COG0477	Major facilitator Superfamily
BEK99_RS12580	COG0667	Aldo Keto reductase
BEK99_RS12590	COG1028	Short-chain dehydrogenase reductase Sdr
BEK99_RS12600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BEK99_RS12625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BEK99_RS12630	COG1028	Short-chain dehydrogenase reductase Sdr
BEK99_RS12655	COG1288	antiporter activity
BEK99_RS12665	COG3871	stress protein (general stress protein 26)
BEK99_RS12670	COG1929	Belongs to the glycerate kinase type-1 family
BEK99_RS12675	COG1511	domain protein
BEK99_RS12685	COG0604	alcohol dehydrogenase
BEK99_RS12690	COG0300	oxidoreductase activity
BEK99_RS12700	COG0579	oxidoreductase
BEK99_RS12705	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BEK99_RS12720	COG0561	phosphatase activity
BEK99_RS12725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BEK99_RS12730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BEK99_RS12740	COG1757	Na H antiporter
BEK99_RS12745	COG2326	polyphosphate kinase activity
BEK99_RS12755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BEK99_RS12770	COG0596	Alpha beta hydrolase
BEK99_RS12780	COG4195	phage-related replication protein
BEK99_RS12810	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BEK99_RS12845	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BEK99_RS12850	COG0549	Belongs to the carbamate kinase family
BEK99_RS12855	COG1288	antiporter activity
BEK99_RS12865	COG1288	antiporter activity
BEK99_RS12875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BEK99_RS12890	COG0706	membrane insertase activity
BEK99_RS12905	COG0583	DNA-binding transcription factor activity
BEK99_RS12910	COG3842	ATPase activity
BEK99_RS12915	COG1840	ABC-type Fe3 transport system, periplasmic component
BEK99_RS12950	COG1028	Short-chain dehydrogenase reductase Sdr
BEK99_RS12975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BEK99_RS12980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BEK99_RS12995	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring