locus-tag	class	description
LGV34_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGV34_RS00010	COG0592	DNA-directed DNA polymerase activity
LGV34_RS00015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGV34_RS00030	COG0187	DNA topoisomerase II activity
LGV34_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGV34_RS00040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGV34_RS00045	COG2986	histidine ammonia-lyase
LGV34_RS00050	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGV34_RS00055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LGV34_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LGV34_RS00070	COG4241	membrane
LGV34_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LGV34_RS00080	COG0359	binds to the 23S rRNA
LGV34_RS00085	COG0305	Participates in initiation and elongation during chromosome replication
LGV34_RS00090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGV34_RS00110	COG0745	RESPONSE REGULATOR receiver
LGV34_RS00115	COG5002	protein histidine kinase activity
LGV34_RS00120	COG4863	YycH protein
LGV34_RS00130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGV34_RS00155	COG0789	Transcriptional regulator
LGV34_RS00165	COG0702	epimerase
LGV34_RS00170	COG2130	NADP-dependent
LGV34_RS00185	COG0702	epimerase
LGV34_RS00190	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LGV34_RS00250	COG0270	DNA (cytosine-5-)-methyltransferase activity
LGV34_RS00290	COG0745	RESPONSE REGULATOR receiver
LGV34_RS00295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGV34_RS00300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGV34_RS00305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LGV34_RS00310	COG2188	Transcriptional regulator
LGV34_RS00315	COG2222	sugar isomerase
LGV34_RS00320	COG3684	Belongs to the aldolase LacD family
LGV34_RS00330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGV34_RS00330	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGV34_RS00335	COG3715	PTS system
LGV34_RS00340	COG3716	PTS system mannose fructose sorbose family IID component
LGV34_RS00350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGV34_RS00355	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LGV34_RS00360	COG0039	L-malate dehydrogenase activity
LGV34_RS00365	COG1328	CTP reductase activity
LGV34_RS00370	COG0602	queuosine metabolic process
LGV34_RS00400	COG1705	Flagellar rod assembly protein muramidase FlgJ
LGV34_RS00400	COG3942	CHAP domain
LGV34_RS00415	COG4716	Myosin-crossreactive antigen
LGV34_RS00435	COG2723	6-phospho-beta-galactosidase activity
LGV34_RS00440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGV34_RS00450	COG3655	Transcriptional regulator
LGV34_RS00455	COG2311	Membrane
LGV34_RS00465	COG2188	Transcriptional regulator
LGV34_RS00470	COG0813	purine-nucleoside phosphorylase activity
LGV34_RS00475	COG2814	Major facilitator Superfamily
LGV34_RS00500	COG1401	restriction endodeoxyribonuclease activity
LGV34_RS00505	COG4268	DNA restriction-modification system
LGV34_RS00520	COG0415	Belongs to the DNA photolyase family
LGV34_RS00555	COG1174	glycine betaine transport
LGV34_RS00565	COG1174	glycine betaine transport
LGV34_RS00585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGV34_RS00605	COG2235	arginine
LGV34_RS00610	COG1438	arginine binding
LGV34_RS00615	COG2814	Major facilitator Superfamily
LGV34_RS00625	COG0579	oxidoreductase
LGV34_RS00630	COG1755	Isoprenylcysteine carboxyl methyltransferase
LGV34_RS00635	COG1113	amino acid transport
LGV34_RS00645	COG1473	amidohydrolase
LGV34_RS00675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGV34_RS00685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGV34_RS00690	COG1335	isochorismatase
LGV34_RS00700	COG1914	H( )-stimulated, divalent metal cation uptake system
LGV34_RS00705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGV34_RS00710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LGV34_RS00715	COG0156	8-amino-7-oxononanoate synthase activity
LGV34_RS00725	COG1620	l-lactate permease
LGV34_RS00730	COG3391	amine dehydrogenase activity
LGV34_RS00745	COG1073	alpha beta
LGV34_RS00755	COG0653	protein targeting
LGV34_RS00760	COG0438	transferase activity, transferring glycosyl groups
LGV34_RS00770	COG0384	phenazine biosynthesis protein PhzF
LGV34_RS00795	COG0563	adenylate kinase activity
LGV34_RS00805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGV34_RS00810	COG0730	response to heat
LGV34_RS00815	COG1937	Protein conserved in bacteria
LGV34_RS00820	COG2210	Belongs to the sulfur carrier protein TusA family
LGV34_RS00825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGV34_RS00830	COG1609	Transcriptional regulator
LGV34_RS00835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGV34_RS00840	COG1869	D-ribose catabolic process
LGV34_RS00845	COG1129	ABC transporter
LGV34_RS00850	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGV34_RS00855	COG1879	ABC-type sugar transport system periplasmic component
LGV34_RS00860	COG2814	Major facilitator Superfamily
LGV34_RS00865	COG0583	DNA-binding transcription factor activity
LGV34_RS00870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGV34_RS00875	COG0025	NhaP-type Na H and K H
LGV34_RS00880	COG3314	Sporulation integral membrane protein YlbJ
LGV34_RS00890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGV34_RS00900	COG3037	sugar-specific permease SgaT UlaA
LGV34_RS00945	COG2814	Major facilitator Superfamily
LGV34_RS00950	COG1335	isochorismatase
LGV34_RS01005	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGV34_RS01025	COG2814	Major facilitator Superfamily
LGV34_RS01030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGV34_RS01050	COG1115	amino acid carrier protein
LGV34_RS01060	COG0668	transmembrane transport
LGV34_RS01075	COG4195	phage-related replication protein
LGV34_RS01095	COG2843	Capsule synthesis protein
LGV34_RS01105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LGV34_RS01125	COG2205	protein histidine kinase activity
LGV34_RS01130	COG0745	RESPONSE REGULATOR receiver
LGV34_RS01135	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGV34_RS01145	COG0586	Pfam SNARE associated Golgi protein
LGV34_RS01150	COG1785	Belongs to the alkaline phosphatase family
LGV34_RS01155	COG1785	Belongs to the alkaline phosphatase family
LGV34_RS01165	COG0494	nUDIX hydrolase
LGV34_RS01170	COG0513	Belongs to the DEAD box helicase family
LGV34_RS01195	COG1510	regulation of RNA biosynthetic process
LGV34_RS01200	COG1012	belongs to the aldehyde dehydrogenase family
LGV34_RS01205	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGV34_RS01245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGV34_RS01250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGV34_RS01275	COG2271	Major facilitator Superfamily
LGV34_RS01280	COG0529	Catalyzes the synthesis of activated sulfate
LGV34_RS01285	COG2046	Belongs to the sulfate adenylyltransferase family
LGV34_RS01290	COG0730	response to heat
LGV34_RS01300	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGV34_RS01305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGV34_RS01310	COG0175	sulfate reduction
LGV34_RS01315	COG2376	Dihydroxyacetone kinase
LGV34_RS01320	COG1461	Dihydroxyacetone kinase
LGV34_RS01335	COG2824	Alkylphosphonate utilization operon protein PhnA
LGV34_RS01340	COG1012	belongs to the aldehyde dehydrogenase family
LGV34_RS01350	COG0596	Alpha beta hydrolase
LGV34_RS01360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGV34_RS01360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGV34_RS01360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGV34_RS01365	COG3942	CHAP domain
LGV34_RS01365	COG1705	Flagellar rod assembly protein muramidase FlgJ
LGV34_RS01385	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGV34_RS01390	COG0747	negative chemotaxis
LGV34_RS01415	COG0463	Glycosyl transferase, family 2
LGV34_RS01415	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LGV34_RS01435	COG1263	PTS System
LGV34_RS01435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGV34_RS01465	COG3001	Fructosamine kinase
LGV34_RS01485	COG1136	(ABC) transporter
LGV34_RS01490	COG1136	(ABC) transporter
LGV34_RS01490	COG0577	efflux transmembrane transporter activity
LGV34_RS01505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGV34_RS01515	COG0745	RESPONSE REGULATOR receiver
LGV34_RS01520	COG5002	protein histidine kinase activity
LGV34_RS01540	COG4413	Urea transporter
LGV34_RS01550	COG0832	Belongs to the urease beta subunit family
LGV34_RS01555	COG0804	urea catabolic process
LGV34_RS01560	COG0717	Belongs to the dCTP deaminase family
LGV34_RS01565	COG0523	cobalamin synthesis protein
LGV34_RS01575	COG1114	Component of the transport system for branched-chain amino acids
LGV34_RS01580	COG3189	MarR family transcriptional regulator
LGV34_RS01595	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGV34_RS01600	COG4605	iron ion homeostasis
LGV34_RS01605	COG4604	ABC transporter, ATP-binding protein
LGV34_RS01610	COG4607	ABC-type enterochelin transport system periplasmic component
LGV34_RS01620	COG1846	Transcriptional regulator
LGV34_RS01625	COG0778	Nitroreductase
LGV34_RS01630	COG2357	RelA SpoT domain protein
LGV34_RS01635	COG0739	heme binding
LGV34_RS01645	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGV34_RS01655	COG3942	CHAP domain
LGV34_RS01670	COG2267	carboxylic ester hydrolase activity
LGV34_RS01675	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LGV34_RS01680	COG2814	Major facilitator Superfamily
LGV34_RS01695	COG1028	Short-chain dehydrogenase reductase Sdr
LGV34_RS01700	COG0753	catalase activity
LGV34_RS01720	COG1028	Short-chain dehydrogenase reductase Sdr
LGV34_RS01745	COG0494	nUDIX hydrolase
LGV34_RS01760	COG3835	regulator
LGV34_RS01775	COG3961	Belongs to the TPP enzyme family
LGV34_RS01780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LGV34_RS01785	COG0512	Glutamine amidotransferase of anthranilate synthase
LGV34_RS01790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGV34_RS01795	COG0134	indole-3-glycerol-phosphate synthase activity
LGV34_RS01800	COG0135	phosphoribosylanthranilate isomerase activity
LGV34_RS01805	COG0133	tryptophan synthase activity
LGV34_RS01810	COG0159	tryptophan synthase activity
LGV34_RS01815	COG1011	Hydrolase
LGV34_RS01830	COG1132	(ABC) transporter
LGV34_RS01835	COG1132	(ABC) transporter
LGV34_RS01840	COG0789	Transcriptional regulator
LGV34_RS01845	COG0346	lactoylglutathione lyase activity
LGV34_RS01850	COG3871	stress protein (general stress protein 26)
LGV34_RS01855	COG1115	amino acid carrier protein
LGV34_RS01865	COG2814	Major facilitator Superfamily
LGV34_RS01870	COG2271	Major facilitator Superfamily
LGV34_RS01875	COG3764	Sortase (surface protein transpeptidase)
LGV34_RS01880	COG1929	Belongs to the glycerate kinase type-1 family
LGV34_RS01900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGV34_RS01910	COG0702	epimerase
LGV34_RS01920	COG3775	system Galactitol-specific IIC component
LGV34_RS01940	COG1760	l-serine dehydratase
LGV34_RS01945	COG1760	l-serine dehydratase
LGV34_RS01970	COG3201	nicotinamide mononucleotide transporter
LGV34_RS01975	COG0471	metal ion transport
LGV34_RS01990	COG0454	-acetyltransferase
LGV34_RS02005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGV34_RS02010	COG2146	nitrite reductase [NAD(P)H] activity
LGV34_RS02015	COG1648	precorrin-2 dehydrogenase activity
LGV34_RS02015	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGV34_RS02030	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LGV34_RS02035	COG1140	nitrate reductase beta subunit
LGV34_RS02040	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LGV34_RS02045	COG2181	nitrate reductase activity
LGV34_RS02055	COG4585	Histidine kinase
LGV34_RS02060	COG2197	response regulator
LGV34_RS02065	COG2223	nitrite transmembrane transporter activity
LGV34_RS02070	COG4187	Peptidase family M20/M25/M40
LGV34_RS02080	COG1363	Peptidase, m42
LGV34_RS02085	COG0697	spore germination
LGV34_RS02105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGV34_RS02120	COG1846	Transcriptional regulator
LGV34_RS02125	COG1283	sodium-dependent phosphate transmembrane transporter activity
LGV34_RS02150	COG0492	ferredoxin-NADP+ reductase activity
LGV34_RS02155	COG2814	Major facilitator Superfamily
LGV34_RS02160	COG0604	alcohol dehydrogenase
LGV34_RS02175	COG1620	l-lactate permease
LGV34_RS02185	COG0579	oxidoreductase
LGV34_RS02200	COG0577	efflux transmembrane transporter activity
LGV34_RS02205	COG1136	(ABC) transporter
LGV34_RS02210	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LGV34_RS02225	COG4640	response to antibiotic
LGV34_RS02240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGV34_RS02245	COG0657	acetylesterase activity
LGV34_RS02265	COG1304	FMN binding
LGV34_RS02270	COG0523	cobalamin synthesis protein
LGV34_RS02275	COG0786	glutamate:sodium symporter activity
LGV34_RS02280	COG2207	Transcriptional regulator
LGV34_RS02290	COG1757	Na H antiporter
LGV34_RS02295	COG2094	Belongs to the DNA glycosylase MPG family
LGV34_RS02300	COG3152	Membrane
LGV34_RS02305	COG4152	abc transporter atp-binding protein
LGV34_RS02310	COG1668	transmembrane transport
LGV34_RS02315	COG1742	UPF0060 membrane protein
LGV34_RS02320	COG1476	TRANSCRIPTIONal
LGV34_RS02330	COG2258	MOSC domain
LGV34_RS02335	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGV34_RS02350	COG0583	DNA-binding transcription factor activity
LGV34_RS02355	COG3314	Sporulation integral membrane protein YlbJ
LGV34_RS02360	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGV34_RS02365	COG1228	amidohydrolase
LGV34_RS02370	COG0659	secondary active sulfate transmembrane transporter activity
LGV34_RS02405	COG0346	lactoylglutathione lyase activity
LGV34_RS02410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGV34_RS02435	COG1113	amino acid transport
LGV34_RS02445	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LGV34_RS02470	COG0483	inositol monophosphate 1-phosphatase activity
LGV34_RS02475	COG1316	TRANSCRIPTIONal
LGV34_RS02485	COG3383	formate dehydrogenase (NAD+) activity
LGV34_RS02515	COG3942	CHAP domain
LGV34_RS02530	COG1757	Na H antiporter
LGV34_RS02540	COG3942	CHAP domain
LGV34_RS02565	COG1960	acyl-CoA dehydrogenase activity
LGV34_RS02570	COG2832	Protein of unknown function (DUF454)
LGV34_RS02575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LGV34_RS02580	COG1268	BioY protein
LGV34_RS02595	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGV34_RS02600	COG4149	molybdate abc transporter
LGV34_RS02605	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LGV34_RS02610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGV34_RS02615	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGV34_RS02620	COG0315	cyclic pyranopterin monophosphate synthase activity
LGV34_RS02645	COG0746	molybdenum cofactor guanylyltransferase activity
LGV34_RS02650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGV34_RS02675	COG2348	transferase activity, transferring amino-acyl groups
LGV34_RS02680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGV34_RS02685	COG0436	Aminotransferase
LGV34_RS02715	COG2252	PERMEase
LGV34_RS02725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGV34_RS02730	COG0088	Forms part of the polypeptide exit tunnel
LGV34_RS02735	COG0089	rRNA binding
LGV34_RS02740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGV34_RS02745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGV34_RS02750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGV34_RS02755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LGV34_RS02765	COG0255	Belongs to the universal ribosomal protein uL29 family
LGV34_RS02775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGV34_RS02780	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LGV34_RS02790	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LGV34_RS02795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LGV34_RS02810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGV34_RS02815	COG1841	ribosomal large subunit assembly
LGV34_RS02825	COG0201	protein transport
LGV34_RS02840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGV34_RS02850	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LGV34_RS02855	COG0202	RNA polymerase activity
LGV34_RS02860	COG0203	ribosomal protein L17
LGV34_RS02865	COG1122	ATPase activity
LGV34_RS02870	COG1122	ATPase activity
LGV34_RS02880	COG0101	tRNA pseudouridine synthase activity
LGV34_RS02890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGV34_RS02900	COG0698	ribose 5-phosphate isomerase
LGV34_RS02925	COG2723	6-phospho-beta-galactosidase activity
LGV34_RS02930	COG0604	alcohol dehydrogenase
LGV34_RS02935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGV34_RS02945	COG2814	Major facilitator Superfamily
LGV34_RS02950	COG4264	IucA IucC family
LGV34_RS02955	COG2814	Major facilitator Superfamily
LGV34_RS02960	COG4264	IucA IucC family
LGV34_RS02965	COG3457	Alanine racemase
LGV34_RS02970	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LGV34_RS02975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGV34_RS02980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGV34_RS02990	COG1988	membrane-bound metal-dependent
LGV34_RS02995	COG4284	Utp--glucose-1-phosphate uridylyltransferase
LGV34_RS03000	COG1272	protein, Hemolysin III
LGV34_RS03020	COG2814	Major facilitator Superfamily
LGV34_RS03025	COG0489	protein tyrosine kinase activity
LGV34_RS03090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGV34_RS03110	COG1119	ATPase activity
LGV34_RS03125	COG2186	Transcriptional regulator
LGV34_RS03130	COG1482	cell wall glycoprotein biosynthetic process
LGV34_RS03145	COG1757	Na H antiporter
LGV34_RS03155	COG0813	purine-nucleoside phosphorylase activity
LGV34_RS03190	COG5146	pantothenate kinase activity
LGV34_RS03205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGV34_RS03215	COG0504	CTP synthase activity
LGV34_RS03225	COG0191	fructose-bisphosphate aldolase activity
LGV34_RS03230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGV34_RS03235	COG1733	regulation of RNA biosynthetic process
LGV34_RS03245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGV34_RS03250	COG0254	rRNA binding
LGV34_RS03255	COG1435	thymidine kinase activity
LGV34_RS03260	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGV34_RS03265	COG2890	protein-(glutamine-N5) methyltransferase activity
LGV34_RS03270	COG0009	L-threonylcarbamoyladenylate synthase
LGV34_RS03280	COG4475	Protein of unknown function (DUF436)
LGV34_RS03285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LGV34_RS03290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGV34_RS03295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGV34_RS03305	COG0356	it plays a direct role in the translocation of protons across the membrane
LGV34_RS03310	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LGV34_RS03315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGV34_RS03320	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LGV34_RS03325	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGV34_RS03330	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGV34_RS03350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGV34_RS03360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGV34_RS03385	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LGV34_RS03395	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LGV34_RS03400	COG0352	thiamine-phosphate diphosphorylase activity
LGV34_RS03405	COG0706	membrane insertase activity
LGV34_RS03410	COG1418	mRNA catabolic process
LGV34_RS03420	COG1937	Protein conserved in bacteria
LGV34_RS03430	COG2608	mercury ion transmembrane transporter activity
LGV34_RS03435	COG2217	Heavy metal translocating P-type atpase
LGV34_RS03445	COG0772	Belongs to the SEDS family
LGV34_RS03450	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGV34_RS03455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGV34_RS03460	COG0513	Belongs to the DEAD box helicase family
LGV34_RS03480	COG0736	holo-[acyl-carrier-protein] synthase activity
LGV34_RS03495	COG2337	Toxic component of a toxin-antitoxin (TA) module
LGV34_RS03500	COG2208	phosphoserine phosphatase activity
LGV34_RS03515	COG1191	sigma factor activity
LGV34_RS03520	COG2183	response to ionizing radiation
LGV34_RS03555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LGV34_RS03560	COG0066	3-isopropylmalate dehydratase activity
LGV34_RS03565	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGV34_RS03570	COG0473	3-isopropylmalate dehydrogenase activity
LGV34_RS03575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LGV34_RS03590	COG0028	Belongs to the TPP enzyme family
LGV34_RS03595	COG0129	dihydroxy-acid dehydratase activity
LGV34_RS03600	COG0802	atpase or kinase
LGV34_RS03605	COG1214	PFAM Peptidase M22, glycoprotease
LGV34_RS03610	COG0456	acetyltransferase
LGV34_RS03615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGV34_RS03620	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGV34_RS03625	COG0488	(ABC) transporter
LGV34_RS03635	COG2391	methyltransferase activity
LGV34_RS03640	COG0425	Belongs to the sulfur carrier protein TusA family
LGV34_RS03645	COG1621	beta-fructofuranosidase activity
LGV34_RS03665	COG4512	PFAM Accessory gene regulator B
LGV34_RS03685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LGV34_RS03725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGV34_RS03730	COG1131	(ABC) transporter
LGV34_RS03740	COG1802	Transcriptional regulator
LGV34_RS03745	COG1070	Carbohydrate kinase
LGV34_RS03750	COG2610	gluconate transmembrane transporter activity
LGV34_RS03755	COG4876	unkown
LGV34_RS03795	COG2706	6-phosphogluconolactonase activity
LGV34_RS03800	COG1012	belongs to the aldehyde dehydrogenase family
LGV34_RS03810	COG1227	inorganic diphosphatase activity
LGV34_RS03815	COG1335	isochorismatase
LGV34_RS03825	COG0077	Prephenate dehydratase
LGV34_RS03835	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGV34_RS03840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGV34_RS03845	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
LGV34_RS03860	COG4496	protein, YerC YecD
LGV34_RS03865	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LGV34_RS03870	COG0210	DNA helicase
LGV34_RS03875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGV34_RS03880	COG4851	CamS sex pheromone cAM373 precursor
LGV34_RS03885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGV34_RS03890	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LGV34_RS03900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LGV34_RS03905	COG1597	lipid kinase activity
LGV34_RS03910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGV34_RS03925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGV34_RS03935	COG1528	Iron-storage protein
LGV34_RS03950	COG4129	membrane
LGV34_RS03955	COG0024	Methionine aminopeptidase
LGV34_RS03980	COG0288	reversible hydration of carbon dioxide
LGV34_RS03985	COG1295	ribonuclease BN
LGV34_RS03995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LGV34_RS04000	COG4840	Belongs to the UPF0435 family
LGV34_RS04005	COG2309	aminopeptidase activity
LGV34_RS04010	COG1607	acyl-coa hydrolase
LGV34_RS04015	COG0535	radical SAM domain protein
LGV34_RS04025	COG0693	protein deglycase activity
LGV34_RS04030	COG0028	Belongs to the TPP enzyme family
LGV34_RS04035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGV34_RS04040	COG2137	regulation of response to DNA damage stimulus
LGV34_RS04050	COG1388	LysM domain
LGV34_RS04050	COG1134	teichoic acid transport
LGV34_RS04060	COG1988	membrane-bound metal-dependent
LGV34_RS04065	COG1194	a g-specific adenine glycosylase
LGV34_RS04070	COG3557	Belongs to the UPF0374 family
LGV34_RS04080	COG0069	glutamate synthase activity
LGV34_RS04085	COG4129	membrane
LGV34_RS04090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGV34_RS04095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGV34_RS04100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGV34_RS04105	COG0735	belongs to the Fur family
LGV34_RS04270	COG0765	amino acid transport
LGV34_RS04275	COG1126	abc transporter atp-binding protein
LGV34_RS04280	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGV34_RS04285	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGV34_RS04290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGV34_RS04295	COG0363	glucosamine-6-phosphate deaminase activity
LGV34_RS04310	COG0114	fumarate hydratase activity
LGV34_RS04315	COG0248	Ppx GppA phosphatase
LGV34_RS04320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGV34_RS04325	COG0564	pseudouridine synthase activity
LGV34_RS04330	COG4585	Histidine kinase
LGV34_RS04330	COG2203	Gaf domain
LGV34_RS04335	COG2197	response regulator
LGV34_RS04345	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGV34_RS04355	COG1301	dicarboxylic acid transport
LGV34_RS04395	COG3679	Belongs to the UPF0342 family
LGV34_RS04400	COG0420	3'-5' exonuclease activity
LGV34_RS04405	COG4717	serine-type aminopeptidase activity
LGV34_RS04410	COG3481	metal-dependent phosphohydrolase, HD sub domain
LGV34_RS04415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGV34_RS04425	COG1846	Transcriptional regulator
LGV34_RS04435	COG0537	adenosine 5'-monophosphoramidase activity
LGV34_RS04440	COG1131	(ABC) transporter
LGV34_RS04455	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGV34_RS04460	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LGV34_RS04465	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGV34_RS04545	COG1028	Short-chain dehydrogenase reductase Sdr
LGV34_RS04560	COG1302	Protein conserved in bacteria
LGV34_RS04565	COG0318	PFAM AMP-dependent synthetase and ligase
LGV34_RS04575	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LGV34_RS04585	COG1506	peptidase
LGV34_RS04590	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGV34_RS04595	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGV34_RS04605	COG0656	L-ascorbic acid biosynthetic process
LGV34_RS04610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LGV34_RS04615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LGV34_RS04625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGV34_RS04640	COG1595	DNA-templated transcription, initiation
LGV34_RS04650	COG4193	domain, Protein
LGV34_RS04650	COG3266	domain, Protein
LGV34_RS04650	COG5632	N-Acetylmuramoyl-L-alanine amidase
LGV34_RS04660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGV34_RS04660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGV34_RS04665	COG0307	riboflavin synthase, alpha
LGV34_RS04670	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGV34_RS04670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGV34_RS04675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGV34_RS04680	COG0506	proline dehydrogenase activity
LGV34_RS04695	COG2267	carboxylic ester hydrolase activity
LGV34_RS04700	COG0039	L-malate dehydrogenase activity
LGV34_RS04710	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LGV34_RS04715	COG1242	4 iron, 4 sulfur cluster binding
LGV34_RS04720	COG2814	Major facilitator Superfamily
LGV34_RS04725	COG0495	leucyl-tRNA aminoacylation
LGV34_RS04730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGV34_RS04735	COG2081	HI0933 family
LGV34_RS04740	COG2244	polysaccharide biosynthetic process
LGV34_RS04745	COG1187	pseudouridine synthase activity
LGV34_RS04755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGV34_RS04760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGV34_RS04765	COG0510	thiamine kinase activity
LGV34_RS04770	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LGV34_RS04775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGV34_RS04785	COG1363	Peptidase, m42
LGV34_RS04790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGV34_RS04795	COG4848	Belongs to the UPF0354 family
LGV34_RS04800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGV34_RS04805	COG1674	ftsk spoiiie
LGV34_RS04810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGV34_RS04825	COG1605	Chorismate mutase
LGV34_RS04825	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LGV34_RS04830	COG1609	Transcriptional regulator
LGV34_RS04835	COG0123	including yeast histone deacetylase and acetoin utilization protein
LGV34_RS04840	COG0454	-acetyltransferase
LGV34_RS04845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGV34_RS04850	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGV34_RS04855	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGV34_RS04865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGV34_RS04870	COG0204	Acyl-transferase
LGV34_RS04880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGV34_RS04885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LGV34_RS04890	COG1764	response to oxidative stress
LGV34_RS04895	COG0584	glycerophosphoryl diester phosphodiesterase
LGV34_RS04905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGV34_RS04910	COG1956	GAF domain-containing protein
LGV34_RS04915	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LGV34_RS04920	COG1104	cysteine desulfurase activity
LGV34_RS04925	COG0301	tRNA thio-modification
LGV34_RS04930	COG0730	response to heat
LGV34_RS04935	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGV34_RS04940	COG0827	DNA restriction-modification system
LGV34_RS04945	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGV34_RS04950	COG0589	response to stress
LGV34_RS04965	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LGV34_RS04975	COG4109	DRTGG domain
LGV34_RS04980	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LGV34_RS04985	COG0587	DNA-directed DNA polymerase activity
LGV34_RS04990	COG0281	malic enzyme
LGV34_RS04995	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LGV34_RS05000	COG0825	malonyl-CoA metabolic process
LGV34_RS05005	COG0205	6-phosphofructokinase activity
LGV34_RS05010	COG0469	pyruvate kinase activity
LGV34_RS05015	COG0372	Belongs to the citrate synthase family
LGV34_RS05020	COG0538	isocitrate dehydrogenase activity
LGV34_RS05025	COG0745	RESPONSE REGULATOR receiver
LGV34_RS05030	COG5002	protein histidine kinase activity
LGV34_RS05035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGV34_RS05035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGV34_RS05040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LGV34_RS05045	COG0237	dephospho-CoA kinase activity
LGV34_RS05050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGV34_RS05055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGV34_RS05060	COG3611	Membrane attachment protein
LGV34_RS05065	COG1484	DNA-dependent DNA replication
LGV34_RS05070	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LGV34_RS05075	COG0833	amino acid
LGV34_RS05080	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LGV34_RS05085	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LGV34_RS05105	COG0544	peptidyl-prolyl cis-trans isomerase activity
LGV34_RS05115	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGV34_RS05120	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGV34_RS05125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGV34_RS05130	COG0181	hydroxymethylbilane synthase activity
LGV34_RS05155	COG2818	Glycosylase
LGV34_RS05160	COG0525	valine-tRNA ligase activity
LGV34_RS05165	COG0285	dihydrofolate synthase activity
LGV34_RS05175	COG2003	Belongs to the UPF0758 family
LGV34_RS05200	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LGV34_RS05205	COG2868	ribosomal protein
LGV34_RS05210	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LGV34_RS05220	COG4492	Belongs to the UPF0735 family
LGV34_RS05245	COG1862	Preprotein translocase
LGV34_RS05250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGV34_RS05250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGV34_RS05255	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LGV34_RS05255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGV34_RS05260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGV34_RS05270	COG1490	D-aminoacyl-tRNA deacylase activity
LGV34_RS05280	COG0124	histidyl-tRNA synthetase
LGV34_RS05285	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGV34_RS05295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGV34_RS05300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGV34_RS05305	COG1959	2 iron, 2 sulfur cluster binding
LGV34_RS05320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGV34_RS05325	COG1104	cysteine desulfurase activity
LGV34_RS05330	COG0482	sulfurtransferase activity
LGV34_RS05340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGV34_RS05350	COG4472	Bacterial protein of unknown function (DUF965)
LGV34_RS05355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGV34_RS05360	COG3906	Belongs to the UPF0473 family
LGV34_RS05365	COG4122	O-methyltransferase activity
LGV34_RS05370	COG0826	peptidase U32
LGV34_RS05375	COG0826	peptidase U32
LGV34_RS05380	COG0572	uridine kinase
LGV34_RS05385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGV34_RS05390	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGV34_RS05395	COG1984	allophanate hydrolase subunit 2
LGV34_RS05400	COG0511	ligase activity, forming carbon-carbon bonds
LGV34_RS05405	COG0439	Biotin carboxylase
LGV34_RS05410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGV34_RS05415	COG1914	H( )-stimulated, divalent metal cation uptake system
LGV34_RS05420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGV34_RS05425	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LGV34_RS05430	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LGV34_RS05440	COG1534	Rna-binding protein
LGV34_RS05450	COG1713	HD superfamily hydrolase involved in NAD metabolism
LGV34_RS05455	COG0799	negative regulation of ribosome biogenesis
LGV34_RS05460	COG2226	methyltransferase
LGV34_RS05465	COG1596	polysaccharide export
LGV34_RS05465	COG1555	photosystem II stabilization
LGV34_RS05470	COG2131	deaminase
LGV34_RS05475	COG2333	competence protein COMEC
LGV34_RS05475	COG0658	competence protein
LGV34_RS05480	COG1466	dna polymerase III delta subunit
LGV34_RS05485	COG0268	Binds directly to 16S ribosomal RNA
LGV34_RS05495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGV34_RS05500	COG1420	regulation of RNA biosynthetic process
LGV34_RS05510	COG0443	Heat shock 70 kDa protein
LGV34_RS05515	COG0484	heat shock protein binding
LGV34_RS05520	COG2264	protein methyltransferase activity
LGV34_RS05525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGV34_RS05530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGV34_RS05540	COG1030	water channel activity
LGV34_RS05545	COG4864	UPF0365 protein
LGV34_RS05555	COG1702	phosphate starvation-inducible protein PhoH
LGV34_RS05560	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGV34_RS05570	COG0295	cytidine deaminase activity
LGV34_RS05575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGV34_RS05585	COG0423	glycine-tRNA ligase activity
LGV34_RS05590	COG0517	IMP dehydrogenase activity
LGV34_RS05595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGV34_RS05600	COG0358	DNA primase activity
LGV34_RS05605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGV34_RS05610	COG2384	SAM-dependent methyltransferase
LGV34_RS05615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGV34_RS05620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGV34_RS05625	COG0513	Belongs to the DEAD box helicase family
LGV34_RS05630	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGV34_RS05635	COG1121	(ABC) transporter
LGV34_RS05640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGV34_RS05650	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LGV34_RS05660	COG0768	penicillin binding
LGV34_RS05665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGV34_RS05670	COG0573	inorganic phosphate transmembrane transporter activity
LGV34_RS05675	COG0581	inorganic phosphate transmembrane transporter activity
LGV34_RS05680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LGV34_RS05685	COG0704	Plays a role in the regulation of phosphate uptake
LGV34_RS05690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGV34_RS05695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGV34_RS05700	COG0457	Tetratricopeptide repeat
LGV34_RS05700	COG0705	Rhomboid family
LGV34_RS05705	COG4483	Protein conserved in bacteria
LGV34_RS05710	COG1940	carbohydrate kinase activity
LGV34_RS05715	COG0011	TIGRFAM Protein of
LGV34_RS05720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGV34_RS05725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGV34_RS05730	COG1459	type II secretion system
LGV34_RS05735	COG4537	Required for transformation and DNA binding
LGV34_RS05750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGV34_RS05755	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGV34_RS05760	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LGV34_RS05765	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LGV34_RS05770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGV34_RS05775	COG0095	Lipoate-protein ligase
LGV34_RS05790	COG0006	proline dipeptidase activity
LGV34_RS05795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGV34_RS05800	COG0511	ligase activity, forming carbon-carbon bonds
LGV34_RS05805	COG0439	Biotin carboxylase
LGV34_RS05810	COG1302	Protein conserved in bacteria
LGV34_RS05815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGV34_RS05825	COG1722	exodeoxyribonuclease VII activity
LGV34_RS05835	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGV34_RS05840	COG1438	arginine binding
LGV34_RS05845	COG0497	DNA recombination
LGV34_RS05850	COG0280	phosphate acetyltransferase
LGV34_RS05860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGV34_RS05865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LGV34_RS05870	COG0022	dehydrogenase e1 component
LGV34_RS05875	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGV34_RS05885	COG4129	membrane
LGV34_RS05895	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGV34_RS05910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGV34_RS05915	COG1234	tRNA 3'-trailer cleavage
LGV34_RS05920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGV34_RS05925	COG0667	Aldo Keto reductase
LGV34_RS05930	COG0494	nUDIX hydrolase
LGV34_RS05935	COG0735	belongs to the Fur family
LGV34_RS05940	COG4974	Belongs to the 'phage' integrase family
LGV34_RS05950	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LGV34_RS05955	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LGV34_RS05960	COG1187	pseudouridine synthase activity
LGV34_RS05965	COG0745	RESPONSE REGULATOR receiver
LGV34_RS05970	COG5002	protein histidine kinase activity
LGV34_RS05980	COG1141	Ferredoxin
LGV34_RS05990	COG0514	ATP-dependent DNA helicase (RecQ)
LGV34_RS06000	COG0492	ferredoxin-NADP+ reductase activity
LGV34_RS06010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LGV34_RS06015	COG0539	negative regulation of cytoplasmic translation
LGV34_RS06040	COG2226	methyltransferase
LGV34_RS06045	COG0142	geranyltranstransferase activity
LGV34_RS06050	COG0105	UTP biosynthetic process
LGV34_RS06055	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LGV34_RS06060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LGV34_RS06065	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGV34_RS06070	COG0457	Tetratricopeptide repeat
LGV34_RS06075	COG5582	Belongs to the UPF0302 family
LGV34_RS06080	COG4347	Protein of unknown function (DUF1405)
LGV34_RS06085	COG2738	Putative neutral zinc metallopeptidase
LGV34_RS06090	COG1694	Mazg nucleotide pyrophosphohydrolase
LGV34_RS06095	COG0438	transferase activity, transferring glycosyl groups
LGV34_RS06100	COG0617	tRNA 3'-terminal CCA addition
LGV34_RS06115	COG0017	Asparaginyl-tRNA synthetase
LGV34_RS06120	COG3935	DnaD domain protein
LGV34_RS06125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGV34_RS06135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGV34_RS06135	COG4499	WXG100 protein secretion system (Wss), protein YukC
LGV34_RS06140	COG3331	DNA recombination
LGV34_RS06150	COG4474	Belongs to the UPF0398 family
LGV34_RS06155	COG3599	regulation of cell shape
LGV34_RS06165	COG0116	Belongs to the methyltransferase superfamily
LGV34_RS06170	COG2962	Rard protein
LGV34_RS06175	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LGV34_RS06180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGV34_RS06190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGV34_RS06200	COG1413	lyase activity
LGV34_RS06210	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LGV34_RS06230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGV34_RS06240	COG4479	Belongs to the UPF0346 family
LGV34_RS06245	COG0793	Belongs to the peptidase S41A family
LGV34_RS06260	COG0671	phosphoesterase, PA-phosphatase related
LGV34_RS06270	COG5002	protein histidine kinase activity
LGV34_RS06275	COG0567	Dehydrogenase, E1 component
LGV34_RS06295	COG0714	Associated with various cellular activities
LGV34_RS06300	COG4548	von Willebrand factor, type A
LGV34_RS06305	COG1114	Component of the transport system for branched-chain amino acids
LGV34_RS06310	COG3853	Toxic anion resistance protein (TelA)
LGV34_RS06330	COG1278	Cold shock
LGV34_RS06345	COG1473	amidohydrolase
LGV34_RS06350	COG2171	N-acyltransferase activity
LGV34_RS06355	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LGV34_RS06360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGV34_RS06365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGV34_RS06370	COG0488	(ABC) transporter
LGV34_RS06375	COG2996	Protein conserved in bacteria
LGV34_RS06385	COG1164	Oligoendopeptidase f
LGV34_RS06400	COG2348	transferase activity, transferring amino-acyl groups
LGV34_RS06405	COG0287	Prephenate dehydrogenase
LGV34_RS06410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGV34_RS06440	COG0628	permease
LGV34_RS06450	COG3711	transcriptional antiterminator
LGV34_RS06455	COG1115	amino acid carrier protein
LGV34_RS06460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGV34_RS06465	COG0187	DNA topoisomerase II activity
LGV34_RS06470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGV34_RS06475	COG4841	protein insertion into membrane
LGV34_RS06480	COG0824	Thioesterase
LGV34_RS06490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGV34_RS06495	COG1970	mechanosensitive ion channel activity
LGV34_RS06500	COG0419	ATPase involved in DNA repair
LGV34_RS06505	COG0420	3'-5' exonuclease activity
LGV34_RS06510	COG4846	Membrane protein involved in cytochrome C biogenesis
LGV34_RS06515	COG3763	UPF0154 protein
LGV34_RS06525	COG4224	UPF0291 protein
LGV34_RS06535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGV34_RS06545	COG0516	GMP reductase activity
LGV34_RS06550	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LGV34_RS06560	COG0753	catalase activity
LGV34_RS06565	COG0833	amino acid
LGV34_RS06575	COG0561	phosphatase activity
LGV34_RS06580	COG0083	homoserine kinase activity
LGV34_RS06585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LGV34_RS06590	COG0460	homoserine dehydrogenase
LGV34_RS06595	COG0527	aspartate kinase activity
LGV34_RS06620	COG2197	response regulator
LGV34_RS06625	COG4585	Histidine kinase
LGV34_RS06635	COG4172	Belongs to the ABC transporter superfamily
LGV34_RS06650	COG0789	Transcriptional regulator
LGV34_RS06655	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LGV34_RS06660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGV34_RS06665	COG0386	Belongs to the glutathione peroxidase family
LGV34_RS06670	COG1923	regulation of RNA biosynthetic process
LGV34_RS06680	COG2267	carboxylic ester hydrolase activity
LGV34_RS06685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGV34_RS06695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGV34_RS06700	COG1619	proteins homologs of microcin C7 resistance protein MccF
LGV34_RS06710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LGV34_RS06730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGV34_RS06740	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGV34_RS06745	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGV34_RS06745	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGV34_RS06750	COG1692	metallophosphoesterase
LGV34_RS06770	COG1418	mRNA catabolic process
LGV34_RS06775	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGV34_RS06780	COG1546	Belongs to the CinA family
LGV34_RS06780	COG1058	Belongs to the CinA family
LGV34_RS06800	COG0300	oxidoreductase activity
LGV34_RS06805	COG0612	Peptidase, M16
LGV34_RS06810	COG0612	Peptidase, M16
LGV34_RS06815	COG2188	Transcriptional regulator
LGV34_RS06825	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LGV34_RS06835	COG1185	polyribonucleotide nucleotidyltransferase activity
LGV34_RS06845	COG0196	riboflavin kinase activity
LGV34_RS06850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LGV34_RS06855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGV34_RS06865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LGV34_RS06870	COG1358	cellular component organization or biogenesis
LGV34_RS06875	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LGV34_RS06880	COG0195	Participates in both transcription termination and antitermination
LGV34_RS06885	COG0779	Required for maturation of 30S ribosomal subunits
LGV34_RS06895	COG0442	prolyl-tRNA aminoacylation
LGV34_RS06905	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LGV34_RS06910	COG4589	Belongs to the CDS family
LGV34_RS06915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LGV34_RS06920	COG0233	cytoplasmic translational termination
LGV34_RS06925	COG0528	UMP kinase activity
LGV34_RS06930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGV34_RS06935	COG0052	Belongs to the universal ribosomal protein uS2 family
LGV34_RS06940	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LGV34_RS06945	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGV34_RS06955	COG4974	Belongs to the 'phage' integrase family
LGV34_RS06960	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LGV34_RS06965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGV34_RS06970	COG0758	DNA mediated transformation
LGV34_RS06980	COG0045	succinate-CoA ligase (ADP-forming) activity
LGV34_RS06990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGV34_RS07005	COG4485	Bacterial membrane protein, YfhO
LGV34_RS07010	COG4485	Bacterial membrane protein, YfhO
LGV34_RS07015	COG0671	phosphoesterase, PA-phosphatase related
LGV34_RS07020	COG0335	large ribosomal subunit rRNA binding
LGV34_RS07025	COG0336	Belongs to the RNA methyltransferase TrmD family
LGV34_RS07035	COG0228	four-way junction DNA binding
LGV34_RS07040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGV34_RS07045	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LGV34_RS07050	COG0552	protein localization to endoplasmic reticulum
LGV34_RS07055	COG1196	nuclear chromosome segregation
LGV34_RS07060	COG0571	ribonuclease III activity
LGV34_RS07065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGV34_RS07070	COG1028	Short-chain dehydrogenase reductase Sdr
LGV34_RS07085	COG1349	DNA-binding transcription factor activity
LGV34_RS07095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGV34_RS07100	COG1760	l-serine dehydratase
LGV34_RS07105	COG1760	l-serine dehydratase
LGV34_RS07115	COG1302	Protein conserved in bacteria
LGV34_RS07125	COG1564	THIamine pyrophosphokinase
LGV34_RS07130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGV34_RS07135	COG1162	GTPase activity
LGV34_RS07140	COG2124	cytochrome p450
LGV34_RS07155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGV34_RS07160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGV34_RS07160	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGV34_RS07165	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGV34_RS07170	COG0242	peptide deformylase activity
LGV34_RS07175	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGV34_RS07180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGV34_RS07185	COG1758	RNA polymerase activity
LGV34_RS07195	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LGV34_RS07205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGV34_RS07215	COG0167	dihydroorotate dehydrogenase activity
LGV34_RS07225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGV34_RS07230	COG0505	Belongs to the CarA family
LGV34_RS07240	COG0540	Belongs to the ATCase OTCase family
LGV34_RS07250	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LGV34_RS07255	COG0564	pseudouridine synthase activity
LGV34_RS07260	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGV34_RS07270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LGV34_RS07275	COG3599	regulation of cell shape
LGV34_RS07285	COG0762	integral membrane protein
LGV34_RS07290	COG1799	cell septum assembly
LGV34_RS07295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGV34_RS07300	COG1496	oxidoreductase activity
LGV34_RS07305	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGV34_RS07310	COG0849	cell division
LGV34_RS07320	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LGV34_RS07330	COG0768	penicillin binding
LGV34_RS07335	COG4839	cell division protein FtsL
LGV34_RS07340	COG0275	rRNA processing
LGV34_RS07345	COG2001	Belongs to the MraZ family
LGV34_RS07350	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LGV34_RS07355	COG0454	-acetyltransferase
LGV34_RS07375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGV34_RS07395	COG2348	transferase activity, transferring amino-acyl groups
LGV34_RS07430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGV34_RS07435	COG1053	succinate dehydrogenase
LGV34_RS07440	COG2009	succinate dehydrogenase
LGV34_RS07445	COG0322	excinuclease ABC activity
LGV34_RS07450	COG3118	belongs to the thioredoxin family
LGV34_RS07455	COG1193	negative regulation of DNA recombination
LGV34_RS07460	COG1796	DNA polymerase
LGV34_RS07460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LGV34_RS07470	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGV34_RS07475	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGV34_RS07480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGV34_RS07480	COG0072	phenylalanine-tRNA ligase activity
LGV34_RS07485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LGV34_RS07490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGV34_RS07495	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGV34_RS07505	COG1323	Belongs to the UPF0348 family
LGV34_RS07510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LGV34_RS07515	COG0742	ribosomal rna small subunit methyltransferase
LGV34_RS07530	COG0584	glycerophosphoryl diester phosphodiesterase
LGV34_RS07535	COG3679	Belongs to the UPF0342 family
LGV34_RS07550	COG0109	protoheme IX farnesyltransferase activity
LGV34_RS07555	COG1612	heme a metabolic process
LGV34_RS07565	COG0772	Belongs to the SEDS family
LGV34_RS07570	COG4838	Belongs to the UPF0358 family
LGV34_RS07575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGV34_RS07580	COG4896	Protein conserved in bacteria
LGV34_RS07585	COG1902	pentaerythritol trinitrate reductase activity
LGV34_RS07590	COG1217	gtp-binding protein TYPA
LGV34_RS07600	COG0483	inositol monophosphate 1-phosphatase activity
LGV34_RS07605	COG4493	Belongs to the UPF0637 family
LGV34_RS07620	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGV34_RS07625	COG1177	transmembrane transport
LGV34_RS07635	COG3842	ATPase activity
LGV34_RS07645	COG4476	Belongs to the UPF0223 family
LGV34_RS07655	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGV34_RS07675	COG0242	peptide deformylase activity
LGV34_RS07685	COG5503	Protein of unknown function (DUF1447)
LGV34_RS07690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LGV34_RS07695	COG0569	domain protein
LGV34_RS07700	COG1294	oxidase, subunit
LGV34_RS07705	COG1271	oxidase subunit
LGV34_RS07715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGV34_RS07730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGV34_RS07745	COG4721	ABC-type cobalt transport system, permease component
LGV34_RS07750	COG1122	ATPase activity
LGV34_RS07760	COG0151	Belongs to the GarS family
LGV34_RS07765	COG0138	bifunctional purine biosynthesis protein purh
LGV34_RS07775	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGV34_RS07780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGV34_RS07785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LGV34_RS07795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LGV34_RS07800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LGV34_RS07810	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGV34_RS07815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGV34_RS07820	COG1017	nitric oxide dioxygenase activity
LGV34_RS07820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGV34_RS07840	COG1845	cytochrome c oxidase, subunit III
LGV34_RS07845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGV34_RS07860	COG1134	teichoic acid transport
LGV34_RS07870	COG1682	transport, permease protein
LGV34_RS07880	COG1215	transferase activity, transferring glycosyl groups
LGV34_RS07890	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGV34_RS07905	COG5632	N-Acetylmuramoyl-L-alanine amidase
LGV34_RS07905	COG1388	LysM domain
LGV34_RS07910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGV34_RS07915	COG1316	TRANSCRIPTIONal
LGV34_RS07935	COG3594	Acyltransferase
LGV34_RS07940	COG0436	Aminotransferase
LGV34_RS07945	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGV34_RS07950	COG0596	Alpha beta hydrolase
LGV34_RS07955	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGV34_RS07960	COG1169	isochorismate synthase
LGV34_RS07965	COG1575	Belongs to the MenA family. Type 1 subfamily
LGV34_RS07970	COG0390	transport system, permease component
LGV34_RS07975	COG4619	ABC transporter
LGV34_RS07980	COG0456	acetyltransferase
LGV34_RS08020	COG4873	Protein conserved in bacteria
LGV34_RS08030	COG0737	Belongs to the 5'-nucleotidase family
LGV34_RS08035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGV34_RS08040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGV34_RS08045	COG0861	Integral membrane protein TerC family
LGV34_RS08060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGV34_RS08065	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGV34_RS08070	COG2814	Major facilitator Superfamily
LGV34_RS08075	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGV34_RS08080	COG2382	esterase
LGV34_RS08085	COG1115	amino acid carrier protein
LGV34_RS08090	COG0628	permease
LGV34_RS08100	COG0569	domain protein
LGV34_RS08100	COG0475	glutathione-regulated potassium exporter activity
LGV34_RS08105	COG2239	Acts as a magnesium transporter
LGV34_RS08110	COG0564	pseudouridine synthase activity
LGV34_RS08115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGV34_RS08120	COG2357	RelA SpoT domain protein
LGV34_RS08135	COG2346	COG2346, Truncated hemoglobins
LGV34_RS08140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LGV34_RS08145	COG1164	Oligoendopeptidase f
LGV34_RS08160	COG1393	Belongs to the ArsC family
LGV34_RS08170	COG4166	transmembrane transport
LGV34_RS08175	COG4608	Belongs to the ABC transporter superfamily
LGV34_RS08180	COG0444	Belongs to the ABC transporter superfamily
LGV34_RS08185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGV34_RS08190	COG0601	transmembrane transport
LGV34_RS08215	COG0542	response to heat
LGV34_RS08220	COG2151	metal-sulfur cluster biosynthetic enzyme
LGV34_RS08225	COG0561	phosphatase activity
LGV34_RS08230	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGV34_RS08240	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGV34_RS08250	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LGV34_RS08260	COG0681	Belongs to the peptidase S26 family
LGV34_RS08265	COG0166	Belongs to the GPI family
LGV34_RS08270	COG0137	argininosuccinate synthase activity
LGV34_RS08275	COG0165	Argininosuccinate lyase
LGV34_RS08280	COG0584	glycerophosphoryl diester phosphodiesterase
LGV34_RS08295	COG1012	belongs to the aldehyde dehydrogenase family
LGV34_RS08300	COG1098	S1 RNA binding domain
LGV34_RS08320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGV34_RS08330	COG2111	Na H antiporter
LGV34_RS08330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGV34_RS08335	COG2111	Na H antiporter
LGV34_RS08340	COG1006	Multisubunit Na H antiporter MnhC subunit
LGV34_RS08345	COG0651	ATP synthesis coupled electron transport
LGV34_RS08350	COG1863	multisubunit Na H antiporter MnhE subunit
LGV34_RS08355	COG2212	antiporter activity
LGV34_RS08360	COG1320	monovalent cation:proton antiporter activity
LGV34_RS08365	COG2050	protein possibly involved in aromatic compounds catabolism
LGV34_RS08370	COG2056	Na+-H+ antiporter family
LGV34_RS08375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGV34_RS08380	COG1252	NADH dehydrogenase
LGV34_RS08385	COG0316	Belongs to the HesB IscA family
LGV34_RS08390	COG4844	belongs to the
LGV34_RS08395	COG1252	NADH dehydrogenase
LGV34_RS08400	COG4837	Protein of unknown function (DUF1462)
LGV34_RS08405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LGV34_RS08410	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LGV34_RS08420	COG1696	Membrane protein involved in D-alanine export
LGV34_RS08425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGV34_RS08435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGV34_RS08445	COG2445	Protein of unknown function DUF86
LGV34_RS08455	COG0706	membrane insertase activity
LGV34_RS08460	COG0706	membrane insertase activity
LGV34_RS08465	COG4470	Protein conserved in bacteria
LGV34_RS08475	COG0737	Belongs to the 5'-nucleotidase family
LGV34_RS08480	COG0730	response to heat
LGV34_RS08485	COG1801	Protein of unknown function DUF72
LGV34_RS08495	COG2070	2-Nitropropane dioxygenase
LGV34_RS08500	COG1253	flavin adenine dinucleotide binding
LGV34_RS08520	COG1388	LysM domain
LGV34_RS08520	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGV34_RS08610	COG4695	Portal protein
LGV34_RS08710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGV34_RS08825	COG0719	Fe-S assembly protein
LGV34_RS08830	COG0822	iron-sulfur transferase activity
LGV34_RS08840	COG0719	Fe-S assembly protein
LGV34_RS08845	COG0396	ATPase activity
LGV34_RS08855	COG1464	Belongs to the NlpA lipoprotein family
LGV34_RS08860	COG2011	ABC-type metal ion transport system permease component
LGV34_RS08865	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LGV34_RS08870	COG0492	ferredoxin-NADP+ reductase activity
LGV34_RS08870	COG3118	belongs to the thioredoxin family
LGV34_RS08885	COG1393	Belongs to the ArsC family
LGV34_RS08890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGV34_RS08900	COG0710	3-dehydroquinate dehydratase activity
LGV34_RS08905	COG1764	response to oxidative stress
LGV34_RS08920	COG0477	Major facilitator Superfamily
LGV34_RS08925	COG2217	Heavy metal translocating P-type atpase
LGV34_RS08965	COG0557	exoribonuclease II activity
LGV34_RS08970	COG1647	Serine aminopeptidase, S33
LGV34_RS08975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGV34_RS08985	COG0148	phosphopyruvate hydratase activity
LGV34_RS08990	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGV34_RS08995	COG0149	triose-phosphate isomerase activity
LGV34_RS09000	COG0126	phosphoglycerate kinase activity
LGV34_RS09025	COG1090	epimerase
LGV34_RS09050	COG1278	Cold shock
LGV34_RS09060	COG0740	serine-type endopeptidase activity
LGV34_RS09065	COG1481	regulation of sporulation
LGV34_RS09070	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGV34_RS09075	COG1660	Displays ATPase and GTPase activities
LGV34_RS09080	COG0492	ferredoxin-NADP+ reductase activity
LGV34_RS09090	COG0110	maltose O-acetyltransferase activity
LGV34_RS09095	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGV34_RS09100	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LGV34_RS09140	COG0653	protein targeting
LGV34_RS09145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGV34_RS09165	COG1739	Uncharacterized protein family UPF0029
LGV34_RS09170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGV34_RS09175	COG2199	diguanylate cyclase activity
LGV34_RS09190	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGV34_RS09195	COG1929	Belongs to the glycerate kinase type-1 family
LGV34_RS09215	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGV34_RS09225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGV34_RS09230	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGV34_RS09235	COG1780	Probably involved in ribonucleotide reductase function
LGV34_RS09245	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LGV34_RS09250	COG3104	oligopeptide transport
LGV34_RS09275	COG1174	glycine betaine transport
LGV34_RS09280	COG0517	IMP dehydrogenase activity
LGV34_RS09280	COG1125	glycine betaine transport
LGV34_RS09285	COG0514	ATP-dependent DNA helicase (RecQ)
LGV34_RS09290	COG0488	(ABC) transporter
LGV34_RS09300	COG1368	sulfuric ester hydrolase activity
LGV34_RS09320	COG0512	Glutamine amidotransferase of anthranilate synthase
LGV34_RS09320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LGV34_RS09325	COG0512	Glutamine amidotransferase of anthranilate synthase
LGV34_RS09325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGV34_RS09335	COG0720	synthase
LGV34_RS09340	COG0602	queuosine metabolic process
LGV34_RS09355	COG0463	Glycosyl transferase, family 2
LGV34_RS09360	COG1253	flavin adenine dinucleotide binding
LGV34_RS09365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGV34_RS09365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGV34_RS09365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGV34_RS09370	COG1105	Belongs to the carbohydrate kinase PfkB family
LGV34_RS09375	COG1349	DNA-binding transcription factor activity
LGV34_RS09380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGV34_RS09385	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LGV34_RS09405	COG1266	CAAX protease self-immunity
LGV34_RS09410	COG0039	L-malate dehydrogenase activity
LGV34_RS09420	COG4989	oxidoreductase activity
LGV34_RS09425	COG0523	cobalamin synthesis protein
LGV34_RS09435	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGV34_RS09440	COG4988	ABC transporter
LGV34_RS09445	COG1968	undecaprenyl-diphosphatase activity
LGV34_RS09465	COG1671	Belongs to the UPF0178 family
LGV34_RS09470	COG1611	Belongs to the LOG family
LGV34_RS09500	COG2839	Protein conserved in bacteria
LGV34_RS09505	COG2814	Major facilitator Superfamily
LGV34_RS09510	COG0583	DNA-binding transcription factor activity
LGV34_RS09520	COG0217	transcriptional regulatory protein
LGV34_RS09530	COG2022	thiamine diphosphate biosynthetic process
LGV34_RS09550	COG3942	CHAP domain
LGV34_RS09550	COG1388	LysM domain
LGV34_RS09555	COG0306	phosphate transporter
LGV34_RS09560	COG1392	Phosphate transport regulator
LGV34_RS09565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGV34_RS09580	COG3949	Membrane
LGV34_RS09585	COG0477	Major facilitator Superfamily
LGV34_RS09595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGV34_RS09600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGV34_RS09605	COG1120	ATPase activity
LGV34_RS09610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LGV34_RS09615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGV34_RS09635	COG1132	(ABC) transporter
LGV34_RS09640	COG1686	Belongs to the peptidase S11 family
LGV34_RS09645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGV34_RS09650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LGV34_RS09655	COG1682	transport, permease protein
LGV34_RS09660	COG1134	teichoic acid transport
LGV34_RS09665	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LGV34_RS09680	COG1321	iron dependent repressor
LGV34_RS09685	COG1121	(ABC) transporter
LGV34_RS09690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGV34_RS09695	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGV34_RS09700	COG1320	monovalent cation:proton antiporter activity
LGV34_RS09705	COG2212	antiporter activity
LGV34_RS09710	COG1863	multisubunit Na H antiporter MnhE subunit
LGV34_RS09715	COG0651	ATP synthesis coupled electron transport
LGV34_RS09720	COG1006	Multisubunit Na H antiporter MnhC subunit
LGV34_RS09725	COG2111	Na H antiporter
LGV34_RS09730	COG2111	Na H antiporter
LGV34_RS09730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGV34_RS09735	COG0582	viral genome integration into host DNA
LGV34_RS09765	COG0596	Alpha beta hydrolase
LGV34_RS09790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGV34_RS09795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LGV34_RS09815	COG1078	dGTPase activity
LGV34_RS09825	COG0655	NAD(P)H dehydrogenase (quinone) activity
LGV34_RS09830	COG4844	belongs to the
LGV34_RS09835	COG0471	metal ion transport
LGV34_RS09850	COG0531	amino acid
LGV34_RS09860	COG0280	phosphate acetyltransferase
LGV34_RS09865	COG0095	Lipoate-protein ligase
LGV34_RS09870	COG2814	Major facilitator Superfamily
LGV34_RS09875	COG1566	PFAM secretion protein HlyD family protein
LGV34_RS09890	COG0531	amino acid
LGV34_RS09895	COG2363	Small membrane protein
LGV34_RS09905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LGV34_RS09925	COG0183	Belongs to the thiolase family
LGV34_RS09930	COG0318	PFAM AMP-dependent synthetase and ligase
LGV34_RS09940	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGV34_RS09945	COG0363	glucosamine-6-phosphate deaminase activity
LGV34_RS09955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LGV34_RS09960	COG1469	GTP cyclohydrolase I activity
LGV34_RS09965	COG0431	NADPH-dependent FMN reductase
LGV34_RS09970	COG0561	phosphatase activity
LGV34_RS09980	COG1428	Deoxynucleoside kinase
LGV34_RS09985	COG1428	Deoxynucleoside kinase
LGV34_RS09995	COG1609	Transcriptional regulator
LGV34_RS10000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGV34_RS10005	COG0561	phosphatase activity
LGV34_RS10010	COG0673	inositol 2-dehydrogenase activity
LGV34_RS10015	COG0738	Major facilitator superfamily
LGV34_RS10025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGV34_RS10035	COG1473	amidohydrolase
LGV34_RS10040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGV34_RS10045	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LGV34_RS10050	COG0049	tRNA binding
LGV34_RS10055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGV34_RS10065	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGV34_RS10075	COG2813	Specifically methylates the guanine in position
LGV34_RS10085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGV34_RS10090	COG0081	regulation of translation
LGV34_RS10095	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGV34_RS10105	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGV34_RS10110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGV34_RS10125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGV34_RS10130	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LGV34_RS10135	COG0215	cysteine-tRNA ligase activity
LGV34_RS10160	COG4956	integral membrane protein (PIN domain superfamily)
LGV34_RS10165	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LGV34_RS10170	COG0542	response to heat
LGV34_RS10175	COG3869	Catalyzes the specific phosphorylation of arginine residues in
LGV34_RS10190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGV34_RS10200	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LGV34_RS10205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGV34_RS10295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGV34_RS10300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGV34_RS10305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGV34_RS10325	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LGV34_RS10330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LGV34_RS10345	COG1098	S1 RNA binding domain
LGV34_RS10355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGV34_RS10360	COG3956	TIGRFAM MazG family protein
LGV34_RS10365	COG2244	polysaccharide biosynthetic process
LGV34_RS10370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGV34_RS10375	COG0193	aminoacyl-tRNA hydrolase activity
LGV34_RS10385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGV34_RS10390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LGV34_RS10395	COG2088	sporulation resulting in formation of a cellular spore
LGV34_RS10400	COG0251	oxidation-reduction process
LGV34_RS10405	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGV34_RS10410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LGV34_RS10415	COG4466	Protein conserved in bacteria
LGV34_RS10420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGV34_RS10425	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LGV34_RS10430	COG0084	hydrolase, TatD family'
LGV34_RS10440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGV34_RS10445	COG2827	Endonuclease containing a URI domain
LGV34_RS10450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LGV34_RS10460	COG1774	PSP1 C-terminal conserved region
LGV34_RS10465	COG0470	DNA polymerase III
LGV34_RS10470	COG3870	Protein conserved in bacteria
LGV34_RS10475	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGV34_RS10480	COG1982	Orn Lys Arg decarboxylase major
LGV34_RS10505	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGV34_RS10510	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LGV34_RS10515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LGV34_RS10530	COG2188	Transcriptional regulator
LGV34_RS10535	COG0366	Alpha amylase catalytic
LGV34_RS10540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGV34_RS10540	COG1263	PTS System
LGV34_RS10560	COG0070	glutamate synthase
LGV34_RS10560	COG0067	glutamate synthase
LGV34_RS10560	COG0069	glutamate synthase activity
LGV34_RS10595	COG1309	transcriptional regulator
LGV34_RS10605	COG1388	LysM domain
LGV34_RS10605	COG3942	CHAP domain
LGV34_RS10610	COG0626	cystathionine gamma-synthase activity
LGV34_RS10615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGV34_RS10625	COG2272	Belongs to the type-B carboxylesterase lipase family
LGV34_RS10630	COG0733	neurotransmitter:sodium symporter activity
LGV34_RS10635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGV34_RS10640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGV34_RS10640	COG0574	Belongs to the PEP-utilizing enzyme family
LGV34_RS10650	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGV34_RS10655	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGV34_RS10665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGV34_RS10680	COG2076	Multidrug Resistance protein
LGV34_RS10685	COG2076	Multidrug Resistance protein
LGV34_RS10695	COG1124	(ABC) transporter
LGV34_RS10700	COG0444	Belongs to the ABC transporter superfamily
LGV34_RS10705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGV34_RS10710	COG0601	transmembrane transport
LGV34_RS10715	COG0747	negative chemotaxis
LGV34_RS10740	COG1011	Hydrolase
LGV34_RS10765	COG1846	Transcriptional regulator
LGV34_RS10770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGV34_RS10780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGV34_RS10785	COG1609	Transcriptional regulator
LGV34_RS10795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGV34_RS10795	COG0519	Catalyzes the synthesis of GMP from XMP
LGV34_RS10800	COG0516	GMP reductase activity
LGV34_RS10800	COG0517	IMP dehydrogenase activity
LGV34_RS10805	COG2233	PERMEase
LGV34_RS10810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGV34_RS10830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGV34_RS10835	COG1823	symporter activity
LGV34_RS10840	COG0778	Nitroreductase
LGV34_RS10850	COG0450	alkyl hydroperoxide reductase
LGV34_RS10855	COG3634	alkyl hydroperoxide reductase activity
LGV34_RS10870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LGV34_RS10880	COG3850	Histidine kinase
LGV34_RS10880	COG5002	protein histidine kinase activity
LGV34_RS10885	COG0745	RESPONSE REGULATOR receiver
LGV34_RS10895	COG1929	Belongs to the glycerate kinase type-1 family
LGV34_RS10915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LGV34_RS10920	COG2011	ABC-type metal ion transport system permease component
LGV34_RS10925	COG1464	Belongs to the NlpA lipoprotein family
LGV34_RS10935	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGV34_RS10945	COG0360	Binds together with S18 to 16S ribosomal RNA
LGV34_RS10950	COG2910	NAD(P)H-binding
LGV34_RS10955	COG0012	GTP binding
LGV34_RS10960	COG4481	Protein conserved in bacteria
LGV34_RS10965	COG0668	transmembrane transport
LGV34_RS10970	COG1475	DNA binding
LGV34_RS10975	COG0626	cystathionine gamma-synthase activity
LGV34_RS10980	COG0626	cystathionine gamma-synthase activity
LGV34_RS10985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LGV34_RS10985	COG0646	methionine synthase
LGV34_RS11000	COG1279	arginine transmembrane transporter activity
LGV34_RS11005	COG0829	nickel cation binding
LGV34_RS11015	COG0830	nickel cation binding
LGV34_RS11020	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LGV34_RS11025	COG1966	Carbon starvation protein
LGV34_RS11030	COG2353	YceI-like domain
LGV34_RS11045	COG2388	GCN5-related N-acetyl-transferase
LGV34_RS11060	COG1846	Transcriptional regulator
LGV34_RS11065	COG0346	lactoylglutathione lyase activity
LGV34_RS11070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LGV34_RS11075	COG0400	carboxylic ester hydrolase activity
LGV34_RS11080	COG1475	DNA binding
LGV34_RS11085	COG0357	Ribosomal RNA small subunit methyltransferase G
LGV34_RS11090	COG0445	tRNA wobble uridine modification
LGV34_RS11095	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGV34_RS11100	COG0594	ribonuclease P activity