locus-tag	class	description
EGX68_RS00010	COG1131	(ABC) transporter
EGX68_RS00050	COG3226	Transcriptional regulator
EGX68_RS00085	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EGX68_RS00090	COG1733	regulation of RNA biosynthetic process
EGX68_RS00100	COG1063	alcohol dehydrogenase
EGX68_RS00105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX68_RS00105	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX68_RS00110	COG0693	protein deglycase activity
EGX68_RS00115	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EGX68_RS00185	COG1475	DNA binding
EGX68_RS00200	COG0175	sulfate reduction
EGX68_RS00205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGX68_RS00210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX68_RS00215	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGX68_RS00225	COG1648	precorrin-2 dehydrogenase activity
EGX68_RS00230	COG0730	response to heat
EGX68_RS00235	COG2046	Belongs to the sulfate adenylyltransferase family
EGX68_RS00240	COG0529	Catalyzes the synthesis of activated sulfate
EGX68_RS00280	COG0772	Belongs to the SEDS family
EGX68_RS00305	COG2814	Major facilitator Superfamily
EGX68_RS00315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGX68_RS00330	COG1136	(ABC) transporter
EGX68_RS00335	COG0577	efflux transmembrane transporter activity
EGX68_RS00335	COG1136	(ABC) transporter
EGX68_RS00340	COG1131	(ABC) transporter
EGX68_RS00350	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX68_RS00355	COG3002	Belongs to the UPF0753 family
EGX68_RS00360	COG5609	conserved protein (DUF2294)
EGX68_RS00365	COG0668	transmembrane transport
EGX68_RS00370	COG4481	Protein conserved in bacteria
EGX68_RS00375	COG0012	GTP binding
EGX68_RS00385	COG0360	Binds together with S18 to 16S ribosomal RNA
EGX68_RS00395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGX68_RS00430	COG0456	acetyltransferase
EGX68_RS00515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGX68_RS00520	COG4195	phage-related replication protein
EGX68_RS00545	COG2076	Multidrug Resistance protein
EGX68_RS00550	COG2076	Multidrug Resistance protein
EGX68_RS00555	COG1280	lysine exporter protein (LysE YggA)
EGX68_RS00580	COG3634	alkyl hydroperoxide reductase activity
EGX68_RS00585	COG0450	alkyl hydroperoxide reductase
EGX68_RS00590	COG3620	sequence-specific DNA binding
EGX68_RS00595	COG0753	catalase activity
EGX68_RS00600	COG0778	Nitroreductase
EGX68_RS00630	COG1823	symporter activity
EGX68_RS00650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX68_RS00655	COG2233	PERMEase
EGX68_RS00660	COG0517	IMP dehydrogenase activity
EGX68_RS00660	COG0516	GMP reductase activity
EGX68_RS00665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGX68_RS00665	COG0519	Catalyzes the synthesis of GMP from XMP
EGX68_RS00705	COG1764	response to oxidative stress
EGX68_RS00755	COG2814	Major facilitator Superfamily
EGX68_RS00760	COG2508	Transcriptional regulator
EGX68_RS00765	COG1953	Uracil, thiamine, allantoin
EGX68_RS00770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EGX68_RS00775	COG1115	amino acid carrier protein
EGX68_RS00780	COG0406	alpha-ribazole phosphatase activity
EGX68_RS00795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGX68_RS00800	COG3257	ureidoglycine aminohydrolase activity
EGX68_RS00805	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EGX68_RS00810	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EGX68_RS00815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGX68_RS00835	COG2807	transmembrane transport
EGX68_RS00845	COG1647	Serine aminopeptidase, S33
EGX68_RS00850	COG5646	InterPro IPR014922
EGX68_RS00855	COG1114	Component of the transport system for branched-chain amino acids
EGX68_RS00860	COG0733	neurotransmitter:sodium symporter activity
EGX68_RS00865	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EGX68_RS00885	COG0129	dihydroxy-acid dehydratase activity
EGX68_RS00895	COG1388	LysM domain
EGX68_RS00895	COG3942	CHAP domain
EGX68_RS00905	COG0494	nUDIX hydrolase
EGX68_RS00925	COG0583	DNA-binding transcription factor activity
EGX68_RS00930	COG0069	glutamate synthase activity
EGX68_RS00930	COG0067	glutamate synthase
EGX68_RS00930	COG0070	glutamate synthase
EGX68_RS00935	COG0493	'glutamate synthase
EGX68_RS00945	COG1263	PTS System
EGX68_RS00945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX68_RS00950	COG0366	Alpha amylase catalytic
EGX68_RS00955	COG2188	Transcriptional regulator
EGX68_RS00970	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGX68_RS00975	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EGX68_RS00980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EGX68_RS01000	COG1982	Orn Lys Arg decarboxylase major
EGX68_RS01005	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EGX68_RS01010	COG3870	Protein conserved in bacteria
EGX68_RS01015	COG0470	DNA polymerase III
EGX68_RS01020	COG1774	PSP1 C-terminal conserved region
EGX68_RS01025	COG4467	Involved in initiation control of chromosome replication
EGX68_RS01030	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EGX68_RS01035	COG2827	Endonuclease containing a URI domain
EGX68_RS01040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGX68_RS01045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX68_RS01045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX68_RS01050	COG0084	hydrolase, TatD family'
EGX68_RS01055	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EGX68_RS01060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGX68_RS01065	COG4466	Protein conserved in bacteria
EGX68_RS01070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EGX68_RS01075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX68_RS01080	COG0251	oxidation-reduction process
EGX68_RS01085	COG2088	sporulation resulting in formation of a cellular spore
EGX68_RS01110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGX68_RS01115	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGX68_RS01120	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EGX68_RS01125	COG0193	aminoacyl-tRNA hydrolase activity
EGX68_RS01130	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGX68_RS01135	COG2244	polysaccharide biosynthetic process
EGX68_RS01140	COG3956	TIGRFAM MazG family protein
EGX68_RS01145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGX68_RS01155	COG1098	S1 RNA binding domain
EGX68_RS01170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGX68_RS01175	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EGX68_RS01195	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGX68_RS01200	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGX68_RS01285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX68_RS01290	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EGX68_RS01295	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EGX68_RS01300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX68_RS01305	COG4463	regulation of RNA biosynthetic process
EGX68_RS01310	COG3880	PFAM UvrB UvrC protein
EGX68_RS01315	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EGX68_RS01320	COG0542	response to heat
EGX68_RS01325	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EGX68_RS01330	COG4956	integral membrane protein (PIN domain superfamily)
EGX68_RS01335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGX68_RS01340	COG1045	serine acetyltransferase
EGX68_RS01345	COG0215	cysteine-tRNA ligase activity
EGX68_RS01350	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EGX68_RS01355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX68_RS01370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGX68_RS01380	COG0250	Participates in transcription elongation, termination and antitermination
EGX68_RS01385	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EGX68_RS01390	COG0081	regulation of translation
EGX68_RS01395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EGX68_RS01400	COG0222	ribosome binding
EGX68_RS01405	COG2813	Specifically methylates the guanine in position
EGX68_RS01410	COG0085	RNA polymerase activity
EGX68_RS01415	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EGX68_RS01425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGX68_RS01430	COG0049	tRNA binding
EGX68_RS01435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EGX68_RS01440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EGX68_RS01445	COG1473	amidohydrolase
EGX68_RS01480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EGX68_RS01485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EGX68_RS01505	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX68_RS01535	COG0583	DNA-binding transcription factor activity
EGX68_RS01550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX68_RS01575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX68_RS01580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX68_RS01585	COG4297	protein containing double-stranded beta helix domain
EGX68_RS01590	COG0546	phosphoglycolate phosphatase activity
EGX68_RS01600	COG1428	Deoxynucleoside kinase
EGX68_RS01605	COG1428	Deoxynucleoside kinase
EGX68_RS01615	COG0561	phosphatase activity
EGX68_RS01620	COG0431	NADPH-dependent FMN reductase
EGX68_RS01635	COG1469	GTP cyclohydrolase I activity
EGX68_RS01640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGX68_RS01650	COG0363	glucosamine-6-phosphate deaminase activity
EGX68_RS01655	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EGX68_RS01665	COG0318	PFAM AMP-dependent synthetase and ligase
EGX68_RS01670	COG0183	Belongs to the thiolase family
EGX68_RS01705	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EGX68_RS01715	COG2363	Small membrane protein
EGX68_RS01735	COG3253	May function as heme-dependent peroxidase
EGX68_RS01740	COG0280	phosphate acetyltransferase
EGX68_RS01745	COG0095	Lipoate-protein ligase
EGX68_RS01765	COG4844	belongs to the
EGX68_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
EGX68_RS01790	COG0667	Aldo Keto reductase
EGX68_RS01795	COG0655	NAD(P)H dehydrogenase (quinone) activity
EGX68_RS01805	COG1078	dGTPase activity
EGX68_RS01820	COG0018	arginyl-trna synthetase
EGX68_RS01825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX68_RS01830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX68_RS01925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX68_RS01925	COG2111	Na H antiporter
EGX68_RS01930	COG2111	Na H antiporter
EGX68_RS01935	COG1006	Multisubunit Na H antiporter MnhC subunit
EGX68_RS01940	COG0651	ATP synthesis coupled electron transport
EGX68_RS01945	COG1863	multisubunit Na H antiporter MnhE subunit
EGX68_RS01950	COG2212	antiporter activity
EGX68_RS01955	COG1320	monovalent cation:proton antiporter activity
EGX68_RS01965	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX68_RS01970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX68_RS01975	COG1121	(ABC) transporter
EGX68_RS01980	COG1321	iron dependent repressor
EGX68_RS01990	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EGX68_RS01995	COG1134	teichoic acid transport
EGX68_RS02000	COG1682	transport, permease protein
EGX68_RS02005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX68_RS02015	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EGX68_RS02020	COG1686	Belongs to the peptidase S11 family
EGX68_RS02025	COG1132	(ABC) transporter
EGX68_RS02030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX68_RS02035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGX68_RS02040	COG1120	ATPase activity
EGX68_RS02045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX68_RS02050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX68_RS02060	COG1461	Dihydroxyacetone kinase
EGX68_RS02065	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EGX68_RS02075	COG3949	Membrane
EGX68_RS02080	COG0657	acetylesterase activity
EGX68_RS02090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX68_RS02095	COG0745	RESPONSE REGULATOR receiver
EGX68_RS02100	COG2205	protein histidine kinase activity
EGX68_RS02105	COG1392	Phosphate transport regulator
EGX68_RS02110	COG0306	phosphate transporter
EGX68_RS02115	COG3942	CHAP domain
EGX68_RS02115	COG1388	LysM domain
EGX68_RS02150	COG0217	transcriptional regulatory protein
EGX68_RS02160	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EGX68_RS02170	COG0583	DNA-binding transcription factor activity
EGX68_RS02180	COG2839	Protein conserved in bacteria
EGX68_RS02185	COG2814	Major facilitator Superfamily
EGX68_RS02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX68_RS02230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX68_RS02235	COG1279	arginine transmembrane transporter activity
EGX68_RS02240	COG1611	Belongs to the LOG family
EGX68_RS02245	COG1671	Belongs to the UPF0178 family
EGX68_RS02255	COG1968	undecaprenyl-diphosphatase activity
EGX68_RS02260	COG4988	ABC transporter
EGX68_RS02265	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGX68_RS02275	COG0523	cobalamin synthesis protein
EGX68_RS02280	COG4989	oxidoreductase activity
EGX68_RS02290	COG0586	Pfam SNARE associated Golgi protein
EGX68_RS02295	COG0039	L-malate dehydrogenase activity
EGX68_RS02325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX68_RS02330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGX68_RS02335	COG1349	DNA-binding transcription factor activity
EGX68_RS02340	COG1105	Belongs to the carbohydrate kinase PfkB family
EGX68_RS02345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX68_RS02345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX68_RS02345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX68_RS02350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGX68_RS02355	COG1253	flavin adenine dinucleotide binding
EGX68_RS02360	COG0656	L-ascorbic acid biosynthetic process
EGX68_RS02365	COG0463	Glycosyl transferase, family 2
EGX68_RS02385	COG0720	synthase
EGX68_RS02390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EGX68_RS02395	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX68_RS02395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX68_RS02400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGX68_RS02410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGX68_RS02420	COG1368	sulfuric ester hydrolase activity
EGX68_RS02430	COG0488	(ABC) transporter
EGX68_RS02435	COG0514	ATP-dependent DNA helicase (RecQ)
EGX68_RS02440	COG1125	glycine betaine transport
EGX68_RS02440	COG0517	IMP dehydrogenase activity
EGX68_RS02445	COG1174	glycine betaine transport
EGX68_RS02450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGX68_RS02460	COG1597	lipid kinase activity
EGX68_RS02465	COG3104	oligopeptide transport
EGX68_RS02470	COG3104	oligopeptide transport
EGX68_RS02475	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EGX68_RS02480	COG0697	spore germination
EGX68_RS02490	COG1780	Probably involved in ribonucleotide reductase function
EGX68_RS02495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX68_RS02500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX68_RS02505	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX68_RS02510	COG4605	iron ion homeostasis
EGX68_RS02515	COG4604	ABC transporter, ATP-binding protein
EGX68_RS02520	COG4607	ABC-type enterochelin transport system periplasmic component
EGX68_RS02535	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGX68_RS02555	COG1929	Belongs to the glycerate kinase type-1 family
EGX68_RS02560	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX68_RS02580	COG2199	diguanylate cyclase activity
EGX68_RS02585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGX68_RS02590	COG1739	Uncharacterized protein family UPF0029
EGX68_RS02605	COG1040	competence protein
EGX68_RS02610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGX68_RS02615	COG0653	protein targeting
EGX68_RS02625	COG3942	CHAP domain
EGX68_RS02625	COG1388	LysM domain
EGX68_RS02640	COG0556	nucleotide-excision repair
EGX68_RS02645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX68_RS02650	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EGX68_RS02655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EGX68_RS02660	COG0110	maltose O-acetyltransferase activity
EGX68_RS02670	COG0492	ferredoxin-NADP+ reductase activity
EGX68_RS02675	COG1660	Displays ATPase and GTPase activities
EGX68_RS02680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EGX68_RS02685	COG1481	regulation of sporulation
EGX68_RS02690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGX68_RS02815	COG0740	serine-type endopeptidase activity
EGX68_RS02825	COG1090	epimerase
EGX68_RS02850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGX68_RS02855	COG0126	phosphoglycerate kinase activity
EGX68_RS02860	COG0149	triose-phosphate isomerase activity
EGX68_RS02865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EGX68_RS02870	COG0148	phosphopyruvate hydratase activity
EGX68_RS02880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX68_RS02885	COG1647	Serine aminopeptidase, S33
EGX68_RS02890	COG0557	exoribonuclease II activity
EGX68_RS02895	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EGX68_RS03020	COG2329	Antibiotic biosynthesis monooxygenase
EGX68_RS03045	COG0346	lactoylglutathione lyase activity
EGX68_RS03130	COG1288	antiporter activity
EGX68_RS03155	COG0346	lactoylglutathione lyase activity
EGX68_RS03190	COG2314	TM2 domain
EGX68_RS03205	COG2851	Citrate transporter
EGX68_RS03220	COG1764	response to oxidative stress
EGX68_RS03225	COG0710	3-dehydroquinate dehydratase activity
EGX68_RS03230	COG0778	Nitroreductase
EGX68_RS03245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX68_RS03250	COG1393	Belongs to the ArsC family
EGX68_RS03255	COG0509	glycine decarboxylation via glycine cleavage system
EGX68_RS03260	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EGX68_RS03265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX68_RS03270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGX68_RS03275	COG2011	ABC-type metal ion transport system permease component
EGX68_RS03280	COG1464	Belongs to the NlpA lipoprotein family
EGX68_RS03290	COG0396	ATPase activity
EGX68_RS03295	COG0719	Fe-S assembly protein
EGX68_RS03305	COG0822	iron-sulfur transferase activity
EGX68_RS03310	COG0719	Fe-S assembly protein
EGX68_RS03400	COG0305	Participates in initiation and elongation during chromosome replication
EGX68_RS03455	COG0756	dUTP diphosphatase activity
EGX68_RS03590	COG1388	LysM domain
EGX68_RS03590	COG5632	N-Acetylmuramoyl-L-alanine amidase
EGX68_RS03600	COG1253	flavin adenine dinucleotide binding
EGX68_RS03605	COG2070	2-Nitropropane dioxygenase
EGX68_RS03610	COG1801	Protein of unknown function DUF72
EGX68_RS03615	COG0730	response to heat
EGX68_RS03620	COG0737	Belongs to the 5'-nucleotidase family
EGX68_RS03625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGX68_RS03630	COG4470	Protein conserved in bacteria
EGX68_RS03640	COG2445	Protein of unknown function DUF86
EGX68_RS03645	COG0647	UMP catabolic process
EGX68_RS03665	COG1696	Membrane protein involved in D-alanine export
EGX68_RS03670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX68_RS03675	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EGX68_RS03680	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EGX68_RS03685	COG4837	Protein of unknown function (DUF1462)
EGX68_RS03690	COG1252	NADH dehydrogenase
EGX68_RS03695	COG4844	belongs to the
EGX68_RS03700	COG0316	Belongs to the HesB IscA family
EGX68_RS03705	COG1252	NADH dehydrogenase
EGX68_RS03710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGX68_RS03715	COG2056	Na+-H+ antiporter family
EGX68_RS03720	COG2050	protein possibly involved in aromatic compounds catabolism
EGX68_RS03730	COG1320	monovalent cation:proton antiporter activity
EGX68_RS03735	COG2212	antiporter activity
EGX68_RS03740	COG1863	multisubunit Na H antiporter MnhE subunit
EGX68_RS03745	COG0651	ATP synthesis coupled electron transport
EGX68_RS03750	COG1006	Multisubunit Na H antiporter MnhC subunit
EGX68_RS03755	COG2111	Na H antiporter
EGX68_RS03760	COG2111	Na H antiporter
EGX68_RS03760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX68_RS03770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX68_RS03775	COG1098	S1 RNA binding domain
EGX68_RS03780	COG1902	pentaerythritol trinitrate reductase activity
EGX68_RS03785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGX68_RS03795	COG0584	glycerophosphoryl diester phosphodiesterase
EGX68_RS03805	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX68_RS03815	COG0165	Argininosuccinate lyase
EGX68_RS03820	COG0137	argininosuccinate synthase activity
EGX68_RS03825	COG0166	Belongs to the GPI family
EGX68_RS03830	COG0398	Pfam SNARE associated Golgi protein
EGX68_RS03845	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EGX68_RS03850	COG1074	ATP-dependent DNA helicase activity
EGX68_RS03855	COG2311	Membrane
EGX68_RS03860	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGX68_RS03870	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX68_RS03875	COG0561	phosphatase activity
EGX68_RS03905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGX68_RS03925	COG0601	transmembrane transport
EGX68_RS03930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX68_RS03935	COG0444	Belongs to the ABC transporter superfamily
EGX68_RS03940	COG4608	Belongs to the ABC transporter superfamily
EGX68_RS03945	COG4166	transmembrane transport
EGX68_RS03950	COG0180	Tryptophanyl-tRNA synthetase
EGX68_RS03955	COG1393	Belongs to the ArsC family
EGX68_RS03960	COG4862	establishment of competence for transformation
EGX68_RS03970	COG1164	Oligoendopeptidase f
EGX68_RS03990	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EGX68_RS03995	COG2346	COG2346, Truncated hemoglobins
EGX68_RS04000	COG4116	CYTH
EGX68_RS04010	COG2357	RelA SpoT domain protein
EGX68_RS04015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGX68_RS04020	COG0564	pseudouridine synthase activity
EGX68_RS04025	COG2239	Acts as a magnesium transporter
EGX68_RS04030	COG0475	glutathione-regulated potassium exporter activity
EGX68_RS04030	COG0569	domain protein
EGX68_RS04040	COG0628	permease
EGX68_RS04045	COG1115	amino acid carrier protein
EGX68_RS04050	COG2382	esterase
EGX68_RS04055	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EGX68_RS04060	COG2814	Major facilitator Superfamily
EGX68_RS04065	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGX68_RS04070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX68_RS04080	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EGX68_RS04085	COG0861	Integral membrane protein TerC family
EGX68_RS04090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX68_RS04095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGX68_RS04100	COG0737	Belongs to the 5'-nucleotidase family
EGX68_RS04110	COG4873	Protein conserved in bacteria
EGX68_RS04125	COG4903	ComK protein
EGX68_RS04150	COG2314	TM2 domain
EGX68_RS04155	COG0456	acetyltransferase
EGX68_RS04160	COG1575	Belongs to the MenA family. Type 1 subfamily
EGX68_RS04165	COG1169	isochorismate synthase
EGX68_RS04170	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EGX68_RS04175	COG2267	carboxylic ester hydrolase activity
EGX68_RS04180	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EGX68_RS04190	COG0436	Aminotransferase
EGX68_RS04195	COG3594	Acyltransferase
EGX68_RS04235	COG1316	TRANSCRIPTIONal
EGX68_RS04240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGX68_RS04255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGX68_RS04260	COG1845	cytochrome c oxidase, subunit III
EGX68_RS04265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGX68_RS04270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGX68_RS04280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EGX68_RS04285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGX68_RS04290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGX68_RS04295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EGX68_RS04300	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGX68_RS04305	COG0047	phosphoribosylformylglycinamidine synthase activity
EGX68_RS04310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGX68_RS04320	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGX68_RS04330	COG0138	bifunctional purine biosynthesis protein purh
EGX68_RS04340	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EGX68_RS04345	COG4172	Belongs to the ABC transporter superfamily
EGX68_RS04365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EGX68_RS04375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX68_RS04380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX68_RS04390	COG1271	oxidase subunit
EGX68_RS04395	COG1294	oxidase, subunit
EGX68_RS04400	COG0569	domain protein
EGX68_RS04405	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EGX68_RS04410	COG5503	Protein of unknown function (DUF1447)
EGX68_RS04420	COG0242	peptide deformylase activity
EGX68_RS04440	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX68_RS04450	COG4476	Belongs to the UPF0223 family
EGX68_RS04460	COG3842	ATPase activity
EGX68_RS04465	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX68_RS04470	COG1177	transmembrane transport
EGX68_RS04475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EGX68_RS04485	COG1914	H( )-stimulated, divalent metal cation uptake system
EGX68_RS04495	COG4493	Belongs to the UPF0637 family
EGX68_RS04500	COG0483	inositol monophosphate 1-phosphatase activity
EGX68_RS04510	COG1217	gtp-binding protein TYPA
EGX68_RS04515	COG4896	Protein conserved in bacteria
EGX68_RS04520	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGX68_RS04525	COG4838	Belongs to the UPF0358 family
EGX68_RS04530	COG0772	Belongs to the SEDS family
EGX68_RS04540	COG1612	heme a metabolic process
EGX68_RS04545	COG0109	protoheme IX farnesyltransferase activity
EGX68_RS04555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX68_RS04565	COG3679	Belongs to the UPF0342 family
EGX68_RS04585	COG0742	ribosomal rna small subunit methyltransferase
EGX68_RS04590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EGX68_RS04600	COG1323	Belongs to the UPF0348 family
EGX68_RS04610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGX68_RS04620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX68_RS04625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EGX68_RS04630	COG0072	phenylalanine-tRNA ligase activity
EGX68_RS04635	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGX68_RS04640	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EGX68_RS04650	COG1796	DNA polymerase
EGX68_RS04650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EGX68_RS04655	COG1193	negative regulation of DNA recombination
EGX68_RS04660	COG3118	belongs to the thioredoxin family
EGX68_RS04665	COG0322	excinuclease ABC activity
EGX68_RS04670	COG2009	succinate dehydrogenase
EGX68_RS04675	COG1053	succinate dehydrogenase
EGX68_RS04680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGX68_RS04685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGX68_RS04720	COG1011	Hydrolase
EGX68_RS04725	COG0454	-acetyltransferase
EGX68_RS04730	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EGX68_RS04735	COG2001	Belongs to the MraZ family
EGX68_RS04740	COG0275	rRNA processing
EGX68_RS04745	COG4839	cell division protein FtsL
EGX68_RS04750	COG0768	penicillin binding
EGX68_RS04755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGX68_RS04760	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGX68_RS04765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGX68_RS04770	COG0849	cell division
EGX68_RS04775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGX68_RS04780	COG1496	oxidoreductase activity
EGX68_RS04785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGX68_RS04790	COG1799	cell septum assembly
EGX68_RS04795	COG0762	integral membrane protein
EGX68_RS04805	COG3599	regulation of cell shape
EGX68_RS04810	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGX68_RS04820	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EGX68_RS04825	COG0564	pseudouridine synthase activity
EGX68_RS04830	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EGX68_RS04835	COG2233	PERMEase
EGX68_RS04840	COG0540	Belongs to the ATCase OTCase family
EGX68_RS04850	COG0505	Belongs to the CarA family
EGX68_RS04855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGX68_RS04860	COG0284	orotidine-5'-phosphate decarboxylase activity
EGX68_RS04865	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EGX68_RS04875	COG2814	Major facilitator Superfamily
EGX68_RS04880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGX68_RS04890	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EGX68_RS04895	COG0194	GDP metabolic process
EGX68_RS04900	COG1758	RNA polymerase activity
EGX68_RS04905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGX68_RS04910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGX68_RS04930	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EGX68_RS04935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGX68_RS04935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGX68_RS04940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EGX68_RS04945	COG0631	protein serine/threonine phosphatase activity
EGX68_RS04955	COG1162	GTPase activity
EGX68_RS04960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGX68_RS04965	COG1564	THIamine pyrophosphokinase
EGX68_RS04970	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EGX68_RS04975	COG1302	Protein conserved in bacteria
EGX68_RS04980	COG1461	Dihydroxyacetone kinase
EGX68_RS04985	COG1760	l-serine dehydratase
EGX68_RS04990	COG1760	l-serine dehydratase
EGX68_RS04995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX68_RS05005	COG1349	DNA-binding transcription factor activity
EGX68_RS05010	COG0416	fatty acid biosynthetic process
EGX68_RS05025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX68_RS05030	COG0571	ribonuclease III activity
EGX68_RS05035	COG1196	nuclear chromosome segregation
EGX68_RS05040	COG0552	protein localization to endoplasmic reticulum
EGX68_RS05045	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EGX68_RS05050	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGX68_RS05070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX68_RS05075	COG1028	Short-chain dehydrogenase reductase Sdr
EGX68_RS05080	COG0228	four-way junction DNA binding
EGX68_RS05085	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EGX68_RS05090	COG0336	Belongs to the RNA methyltransferase TrmD family
EGX68_RS05095	COG0335	large ribosomal subunit rRNA binding
EGX68_RS05105	COG4485	Bacterial membrane protein, YfhO
EGX68_RS05115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGX68_RS05120	COG0045	succinate-CoA ligase (ADP-forming) activity
EGX68_RS05130	COG0758	DNA mediated transformation
EGX68_RS05135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX68_RS05140	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EGX68_RS05145	COG4974	Belongs to the 'phage' integrase family
EGX68_RS05150	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EGX68_RS05155	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EGX68_RS05160	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EGX68_RS05165	COG0052	Belongs to the universal ribosomal protein uS2 family
EGX68_RS05170	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EGX68_RS05175	COG0528	UMP kinase activity
EGX68_RS05180	COG0233	cytoplasmic translational termination
EGX68_RS05185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGX68_RS05190	COG4589	Belongs to the CDS family
EGX68_RS05200	COG0442	prolyl-tRNA aminoacylation
EGX68_RS05205	COG2176	DNA-directed DNA polymerase activity
EGX68_RS05210	COG0779	Required for maturation of 30S ribosomal subunits
EGX68_RS05215	COG0195	Participates in both transcription termination and antitermination
EGX68_RS05220	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EGX68_RS05225	COG1358	cellular component organization or biogenesis
EGX68_RS05230	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EGX68_RS05250	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EGX68_RS05255	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGX68_RS05260	COG0196	riboflavin kinase activity
EGX68_RS05265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EGX68_RS05270	COG1185	polyribonucleotide nucleotidyltransferase activity
EGX68_RS05275	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EGX68_RS05280	COG1674	ftsk spoiiie
EGX68_RS05290	COG0612	Peptidase, M16
EGX68_RS05295	COG0612	Peptidase, M16
EGX68_RS05300	COG0300	oxidoreductase activity
EGX68_RS05310	COG1426	Protein conserved in bacteria
EGX68_RS05320	COG1546	Belongs to the CinA family
EGX68_RS05320	COG1058	Belongs to the CinA family
EGX68_RS05325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGX68_RS05330	COG1418	mRNA catabolic process
EGX68_RS05340	COG1692	metallophosphoesterase
EGX68_RS05345	COG0674	pyruvate-flavodoxin oxidoreductase activity
EGX68_RS05345	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EGX68_RS05350	COG1013	pyruvate-flavodoxin oxidoreductase activity
EGX68_RS05365	COG1959	2 iron, 2 sulfur cluster binding
EGX68_RS05375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGX68_RS05380	COG4550	Control of competence regulator ComK, YlbF/YmcA
EGX68_RS05390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EGX68_RS05395	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGX68_RS05405	COG1619	proteins homologs of microcin C7 resistance protein MccF
EGX68_RS05410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGX68_RS05415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX68_RS05420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX68_RS05430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EGX68_RS05435	COG1923	regulation of RNA biosynthetic process
EGX68_RS05440	COG0386	Belongs to the glutathione peroxidase family
EGX68_RS05445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGX68_RS05450	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EGX68_RS05455	COG0789	Transcriptional regulator
EGX68_RS05460	COG0174	glutamine synthetase
EGX68_RS05515	COG0527	aspartate kinase activity
EGX68_RS05520	COG0460	homoserine dehydrogenase
EGX68_RS05525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EGX68_RS05530	COG0083	homoserine kinase activity
EGX68_RS05535	COG0561	phosphatase activity
EGX68_RS05550	COG1522	sequence-specific DNA binding
EGX68_RS05560	COG0833	amino acid
EGX68_RS05565	COG0753	catalase activity
EGX68_RS05575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGX68_RS05580	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGX68_RS05585	COG0516	GMP reductase activity
EGX68_RS05595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGX68_RS05615	COG3763	UPF0154 protein
EGX68_RS05625	COG4846	Membrane protein involved in cytochrome C biogenesis
EGX68_RS05630	COG0420	3'-5' exonuclease activity
EGX68_RS05635	COG0419	ATPase involved in DNA repair
EGX68_RS05640	COG1970	mechanosensitive ion channel activity
EGX68_RS05645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX68_RS05650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGX68_RS05655	COG0824	Thioesterase
EGX68_RS05660	COG4841	protein insertion into membrane
EGX68_RS05665	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EGX68_RS05675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX68_RS05680	COG1115	amino acid carrier protein
EGX68_RS05685	COG0628	permease
EGX68_RS05700	COG1609	Transcriptional regulator
EGX68_RS05705	COG1869	D-ribose catabolic process
EGX68_RS05710	COG1129	ABC transporter
EGX68_RS05715	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX68_RS05720	COG1879	ABC-type sugar transport system periplasmic component
EGX68_RS05735	COG1942	4-Oxalocrotonate Tautomerase
EGX68_RS05740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGX68_RS05750	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EGX68_RS05755	COG0287	Prephenate dehydrogenase
EGX68_RS05760	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGX68_RS05765	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX68_RS05770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX68_RS05775	COG0134	indole-3-glycerol-phosphate synthase activity
EGX68_RS05785	COG0133	tryptophan synthase activity
EGX68_RS05790	COG0159	tryptophan synthase activity
EGX68_RS05800	COG2348	transferase activity, transferring amino-acyl groups
EGX68_RS05805	COG2348	transferase activity, transferring amino-acyl groups
EGX68_RS05820	COG0789	Transcriptional regulator
EGX68_RS05835	COG0704	Plays a role in the regulation of phosphate uptake
EGX68_RS05840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGX68_RS05845	COG0581	inorganic phosphate transmembrane transporter activity
EGX68_RS05850	COG0573	inorganic phosphate transmembrane transporter activity
EGX68_RS05855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGX68_RS05860	COG2996	Protein conserved in bacteria
EGX68_RS05865	COG0488	(ABC) transporter
EGX68_RS05875	COG0527	aspartate kinase activity
EGX68_RS05880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX68_RS05885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX68_RS05890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGX68_RS05900	COG1473	amidohydrolase
EGX68_RS05915	COG1278	Cold shock
EGX68_RS05925	COG1254	Belongs to the acylphosphatase family
EGX68_RS05935	COG3853	Toxic anion resistance protein (TelA)
EGX68_RS05940	COG1114	Component of the transport system for branched-chain amino acids
EGX68_RS05945	COG4548	von Willebrand factor, type A
EGX68_RS05950	COG0714	Associated with various cellular activities
EGX68_RS05985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGX68_RS05990	COG0673	inositol 2-dehydrogenase activity
EGX68_RS06010	COG2207	Transcriptional regulator
EGX68_RS06010	COG1917	Cupin 2, conserved barrel domain protein
EGX68_RS06020	COG1396	sequence-specific DNA binding
EGX68_RS06025	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX68_RS06030	COG0567	Dehydrogenase, E1 component
EGX68_RS06035	COG5002	protein histidine kinase activity
EGX68_RS06040	COG0745	RESPONSE REGULATOR receiver
EGX68_RS06045	COG0671	phosphoesterase, PA-phosphatase related
EGX68_RS06050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGX68_RS06060	COG0793	Belongs to the peptidase S41A family
EGX68_RS06065	COG4479	Belongs to the UPF0346 family
EGX68_RS06075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGX68_RS06095	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EGX68_RS06105	COG1413	lyase activity
EGX68_RS06110	COG1413	lyase activity
EGX68_RS06120	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGX68_RS06125	COG3545	Serine hydrolase
EGX68_RS06130	COG0328	RNA-DNA hybrid ribonuclease activity
EGX68_RS06135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX68_RS06140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EGX68_RS06150	COG2962	Rard protein
EGX68_RS06155	COG0116	Belongs to the methyltransferase superfamily
EGX68_RS06165	COG3599	regulation of cell shape
EGX68_RS06170	COG4474	Belongs to the UPF0398 family
EGX68_RS06180	COG3331	DNA recombination
EGX68_RS06185	COG4499	WXG100 protein secretion system (Wss), protein YukC
EGX68_RS06185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX68_RS06195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX68_RS06200	COG3935	DnaD domain protein
EGX68_RS06205	COG0017	Asparaginyl-tRNA synthetase
EGX68_RS06210	COG1199	ATP-dependent helicase activity
EGX68_RS06210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGX68_RS06220	COG0617	tRNA 3'-terminal CCA addition
EGX68_RS06225	COG0438	transferase activity, transferring glycosyl groups
EGX68_RS06230	COG1694	Mazg nucleotide pyrophosphohydrolase
EGX68_RS06235	COG2738	Putative neutral zinc metallopeptidase
EGX68_RS06240	COG4347	Protein of unknown function (DUF1405)
EGX68_RS06245	COG5582	Belongs to the UPF0302 family
EGX68_RS06255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGX68_RS06260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EGX68_RS06265	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EGX68_RS06270	COG0105	UTP biosynthetic process
EGX68_RS06275	COG0142	geranyltranstransferase activity
EGX68_RS06280	COG2226	methyltransferase
EGX68_RS06295	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EGX68_RS06300	COG1160	GTP binding
EGX68_RS06305	COG0539	negative regulation of cytoplasmic translation
EGX68_RS06310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EGX68_RS06315	COG0252	asparaginase activity
EGX68_RS06320	COG0492	ferredoxin-NADP+ reductase activity
EGX68_RS06345	COG0514	ATP-dependent DNA helicase (RecQ)
EGX68_RS06355	COG1141	Ferredoxin
EGX68_RS06370	COG0745	RESPONSE REGULATOR receiver
EGX68_RS06375	COG1187	pseudouridine synthase activity
EGX68_RS06380	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGX68_RS06385	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EGX68_RS06395	COG4974	Belongs to the 'phage' integrase family
EGX68_RS06400	COG0735	belongs to the Fur family
EGX68_RS06405	COG0494	nUDIX hydrolase
EGX68_RS06410	COG0667	Aldo Keto reductase
EGX68_RS06420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGX68_RS06425	COG1234	tRNA 3'-trailer cleavage
EGX68_RS06430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGX68_RS06440	COG0366	Alpha amylase catalytic
EGX68_RS06450	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX68_RS06455	COG4129	membrane
EGX68_RS06465	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX68_RS06470	COG0022	dehydrogenase e1 component
EGX68_RS06475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGX68_RS06480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX68_RS06485	COG0280	phosphate acetyltransferase
EGX68_RS06490	COG0497	DNA recombination
EGX68_RS06495	COG1438	arginine binding
EGX68_RS06505	COG1722	exodeoxyribonuclease VII activity
EGX68_RS06510	COG1570	exodeoxyribonuclease VII activity
EGX68_RS06515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGX68_RS06520	COG1302	Protein conserved in bacteria
EGX68_RS06525	COG0439	Biotin carboxylase
EGX68_RS06530	COG0511	ligase activity, forming carbon-carbon bonds
EGX68_RS06535	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EGX68_RS06540	COG0006	proline dipeptidase activity
EGX68_RS06555	COG0095	Lipoate-protein ligase
EGX68_RS06560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX68_RS06570	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGX68_RS06575	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGX68_RS06580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGX68_RS06585	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EGX68_RS06605	COG4537	Required for transformation and DNA binding
EGX68_RS06615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX68_RS06620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX68_RS06625	COG0011	TIGRFAM Protein of
EGX68_RS06630	COG1940	carbohydrate kinase activity
EGX68_RS06635	COG4483	Protein conserved in bacteria
EGX68_RS06640	COG0457	Tetratricopeptide repeat
EGX68_RS06640	COG0705	Rhomboid family
EGX68_RS06645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGX68_RS06650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGX68_RS06655	COG0768	penicillin binding
EGX68_RS06660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGX68_RS06670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX68_RS06675	COG1121	(ABC) transporter
EGX68_RS06680	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EGX68_RS06685	COG0513	Belongs to the DEAD box helicase family
EGX68_RS06695	COG2384	SAM-dependent methyltransferase
EGX68_RS06700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGX68_RS06710	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EGX68_RS06715	COG0517	IMP dehydrogenase activity
EGX68_RS06720	COG0423	glycine-tRNA ligase activity
EGX68_RS06725	COG1381	Involved in DNA repair and RecF pathway recombination
EGX68_RS06730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGX68_RS06750	COG1702	phosphate starvation-inducible protein PhoH
EGX68_RS06760	COG4864	UPF0365 protein
EGX68_RS06770	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EGX68_RS06780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGX68_RS06785	COG2264	protein methyltransferase activity
EGX68_RS06790	COG0484	heat shock protein binding
EGX68_RS06795	COG0443	Heat shock 70 kDa protein
EGX68_RS06800	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGX68_RS06805	COG1420	regulation of RNA biosynthetic process
EGX68_RS06810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX68_RS06815	COG0481	GTPase activity
EGX68_RS06820	COG0268	Binds directly to 16S ribosomal RNA
EGX68_RS06825	COG1466	dna polymerase III delta subunit
EGX68_RS06835	COG2131	deaminase
EGX68_RS06850	COG2226	methyltransferase
EGX68_RS06855	COG0799	negative regulation of ribosome biogenesis
EGX68_RS06860	COG1713	HD superfamily hydrolase involved in NAD metabolism
EGX68_RS06865	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EGX68_RS06870	COG1534	Rna-binding protein
EGX68_RS06875	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGX68_RS06880	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EGX68_RS06885	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EGX68_RS06890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGX68_RS06895	COG1914	H( )-stimulated, divalent metal cation uptake system
EGX68_RS06900	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EGX68_RS06905	COG0439	Biotin carboxylase
EGX68_RS06915	COG1984	allophanate hydrolase subunit 2
EGX68_RS06920	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGX68_RS06925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX68_RS06930	COG0572	uridine kinase
EGX68_RS06935	COG0826	peptidase U32
EGX68_RS06940	COG0826	peptidase U32
EGX68_RS06945	COG4122	O-methyltransferase activity
EGX68_RS06950	COG3906	Belongs to the UPF0473 family
EGX68_RS06955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGX68_RS06960	COG4472	Bacterial protein of unknown function (DUF965)
EGX68_RS06965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EGX68_RS06970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX68_RS06980	COG0482	sulfurtransferase activity
EGX68_RS06985	COG1104	cysteine desulfurase activity
EGX68_RS06990	COG0488	(ABC) transporter
EGX68_RS06995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX68_RS07005	COG1959	2 iron, 2 sulfur cluster binding
EGX68_RS07010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGX68_RS07015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGX68_RS07025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EGX68_RS07030	COG0124	histidyl-tRNA synthetase
EGX68_RS07035	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX68_RS07040	COG1490	D-aminoacyl-tRNA deacylase activity
EGX68_RS07045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX68_RS07050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX68_RS07055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGX68_RS07055	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EGX68_RS07060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX68_RS07060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX68_RS07065	COG1862	Preprotein translocase
EGX68_RS07070	COG0343	queuine tRNA-ribosyltransferase activity
EGX68_RS07075	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EGX68_RS07080	COG2255	four-way junction helicase activity
EGX68_RS07085	COG0632	four-way junction helicase activity
EGX68_RS07090	COG4492	Belongs to the UPF0735 family
EGX68_RS07095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGX68_RS07105	COG2868	ribosomal protein
EGX68_RS07110	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EGX68_RS07120	COG1792	Involved in formation and maintenance of cell shape
EGX68_RS07135	COG2003	Belongs to the UPF0758 family
EGX68_RS07185	COG0285	dihydrofolate synthase activity
EGX68_RS07190	COG0525	valine-tRNA ligase activity
EGX68_RS07195	COG2818	Glycosylase
EGX68_RS07205	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGX68_RS07210	COG0113	porphobilinogen synthase activity
EGX68_RS07220	COG0181	hydroxymethylbilane synthase activity
EGX68_RS07225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX68_RS07230	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EGX68_RS07235	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EGX68_RS07240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EGX68_RS07245	COG0544	peptidyl-prolyl cis-trans isomerase activity
EGX68_RS07255	COG4112	unkown
EGX68_RS07260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EGX68_RS07265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EGX68_RS07270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EGX68_RS07275	COG0833	amino acid
EGX68_RS07280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EGX68_RS07285	COG1484	DNA-dependent DNA replication
EGX68_RS07295	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EGX68_RS07300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGX68_RS07305	COG0237	dephospho-CoA kinase activity
EGX68_RS07315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX68_RS07315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX68_RS07320	COG5002	protein histidine kinase activity
EGX68_RS07325	COG0745	RESPONSE REGULATOR receiver
EGX68_RS07330	COG0538	isocitrate dehydrogenase activity
EGX68_RS07335	COG0372	Belongs to the citrate synthase family
EGX68_RS07340	COG1113	amino acid transport
EGX68_RS07350	COG0469	pyruvate kinase activity
EGX68_RS07355	COG0205	6-phosphofructokinase activity
EGX68_RS07360	COG0825	malonyl-CoA metabolic process
EGX68_RS07365	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EGX68_RS07370	COG0281	malic enzyme
EGX68_RS07375	COG0587	DNA-directed DNA polymerase activity
EGX68_RS07380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EGX68_RS07385	COG4109	DRTGG domain
EGX68_RS07395	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EGX68_RS07400	COG0006	proline dipeptidase activity
EGX68_RS07405	COG3142	Participates in the control of copper homeostasis
EGX68_RS07410	COG0686	Belongs to the AlaDH PNT family
EGX68_RS07415	COG0589	response to stress
EGX68_RS07425	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGX68_RS07435	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EGX68_RS07440	COG1714	RDD family
EGX68_RS07445	COG0616	signal peptide processing
EGX68_RS07455	COG0301	tRNA thio-modification
EGX68_RS07460	COG1104	cysteine desulfurase activity
EGX68_RS07465	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EGX68_RS07470	COG1956	GAF domain-containing protein
EGX68_RS07480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGX68_RS07490	COG0584	glycerophosphoryl diester phosphodiesterase
EGX68_RS07495	COG1764	response to oxidative stress
EGX68_RS07500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EGX68_RS07505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGX68_RS07520	COG0204	Acyl-transferase
EGX68_RS07525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX68_RS07530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGX68_RS07535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX68_RS07540	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EGX68_RS07545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGX68_RS07550	COG0454	-acetyltransferase
EGX68_RS07555	COG0123	including yeast histone deacetylase and acetoin utilization protein
EGX68_RS07560	COG1609	Transcriptional regulator
EGX68_RS07565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EGX68_RS07565	COG1605	Chorismate mutase
EGX68_RS07575	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EGX68_RS07580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGX68_RS07585	COG1674	ftsk spoiiie
EGX68_RS07590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX68_RS07595	COG4848	Belongs to the UPF0354 family
EGX68_RS07600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX68_RS07605	COG1363	Peptidase, m42
EGX68_RS07615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX68_RS07620	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGX68_RS07625	COG0510	thiamine kinase activity
EGX68_RS07630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX68_RS07635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGX68_RS07645	COG1187	pseudouridine synthase activity
EGX68_RS07650	COG2244	polysaccharide biosynthetic process
EGX68_RS07655	COG2081	HI0933 family
EGX68_RS07670	COG0495	leucyl-tRNA aminoacylation
EGX68_RS07675	COG2814	Major facilitator Superfamily
EGX68_RS07680	COG1242	4 iron, 4 sulfur cluster binding
EGX68_RS07685	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EGX68_RS07695	COG0039	L-malate dehydrogenase activity
EGX68_RS07700	COG2267	carboxylic ester hydrolase activity
EGX68_RS07705	COG0506	proline dehydrogenase activity
EGX68_RS07710	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EGX68_RS07715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX68_RS07715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX68_RS07720	COG0307	riboflavin synthase, alpha
EGX68_RS07725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX68_RS07725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX68_RS07755	COG5632	N-Acetylmuramoyl-L-alanine amidase
EGX68_RS07755	COG3266	domain, Protein
EGX68_RS07755	COG4193	domain, Protein
EGX68_RS07765	COG1595	DNA-templated transcription, initiation
EGX68_RS07780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGX68_RS07790	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX68_RS07795	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX68_RS07800	COG0656	L-ascorbic acid biosynthetic process
EGX68_RS07810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EGX68_RS07815	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EGX68_RS07820	COG1506	peptidase
EGX68_RS07830	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EGX68_RS07890	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EGX68_RS07895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGX68_RS07900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EGX68_RS07910	COG4473	ABC transporter
EGX68_RS07915	COG1131	(ABC) transporter
EGX68_RS07920	COG0537	adenosine 5'-monophosphoramidase activity
EGX68_RS07935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX68_RS07970	COG4717	serine-type aminopeptidase activity
EGX68_RS07975	COG0420	3'-5' exonuclease activity
EGX68_RS07980	COG3679	Belongs to the UPF0342 family
EGX68_RS07985	COG4399	Belongs to the UPF0754 family
EGX68_RS07995	COG0788	formyltetrahydrofolate deformylase activity
EGX68_RS08015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGX68_RS08025	COG1301	dicarboxylic acid transport
EGX68_RS08030	COG2197	response regulator
EGX68_RS08035	COG2203	Gaf domain
EGX68_RS08035	COG4585	Histidine kinase
EGX68_RS08040	COG0564	pseudouridine synthase activity
EGX68_RS08045	COG0114	fumarate hydratase activity
EGX68_RS08060	COG0363	glucosamine-6-phosphate deaminase activity
EGX68_RS08070	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGX68_RS08075	COG1126	abc transporter atp-binding protein
EGX68_RS08080	COG0765	amino acid transport
EGX68_RS08235	COG0735	belongs to the Fur family
EGX68_RS08240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX68_RS08245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGX68_RS08250	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGX68_RS08255	COG4129	membrane
EGX68_RS08265	COG3557	Belongs to the UPF0374 family
EGX68_RS08275	COG1988	membrane-bound metal-dependent
EGX68_RS08285	COG1134	teichoic acid transport
EGX68_RS08295	COG2137	regulation of response to DNA damage stimulus
EGX68_RS08300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX68_RS08305	COG0693	protein deglycase activity
EGX68_RS08315	COG0535	radical SAM domain protein
EGX68_RS08320	COG1607	acyl-coa hydrolase
EGX68_RS08325	COG2309	aminopeptidase activity
EGX68_RS08330	COG4840	Belongs to the UPF0435 family
EGX68_RS08335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX68_RS08345	COG1295	ribonuclease BN
EGX68_RS08350	COG2197	response regulator
EGX68_RS08355	COG4585	Histidine kinase
EGX68_RS08370	COG0024	Methionine aminopeptidase
EGX68_RS08375	COG4129	membrane
EGX68_RS08390	COG1528	Iron-storage protein
EGX68_RS08400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGX68_RS08410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGX68_RS08415	COG1597	lipid kinase activity
EGX68_RS08420	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGX68_RS08425	COG0154	amidase activity
EGX68_RS08430	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGX68_RS08435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX68_RS08440	COG4851	CamS sex pheromone cAM373 precursor
EGX68_RS08445	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGX68_RS08460	COG4496	protein, YerC YecD
EGX68_RS08465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGX68_RS08475	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EGX68_RS08480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGX68_RS08485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EGX68_RS08495	COG0077	Prephenate dehydratase
EGX68_RS08500	COG0471	metal ion transport
EGX68_RS08510	COG1335	isochorismatase
EGX68_RS08515	COG1227	inorganic diphosphatase activity
EGX68_RS08520	COG1012	belongs to the aldehyde dehydrogenase family
EGX68_RS08525	COG2706	6-phosphogluconolactonase activity
EGX68_RS08565	COG1131	(ABC) transporter
EGX68_RS08575	COG1131	(ABC) transporter
EGX68_RS08580	COG1725	Transcriptional regulator
EGX68_RS08605	COG0459	protein refolding
EGX68_RS08610	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EGX68_RS08630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX68_RS08635	COG4512	PFAM Accessory gene regulator B
EGX68_RS08645	COG3290	protein histidine kinase activity
EGX68_RS08650	COG3279	Response regulator of the LytR AlgR family
EGX68_RS08655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX68_RS08660	COG1621	beta-fructofuranosidase activity
EGX68_RS08665	COG0425	Belongs to the sulfur carrier protein TusA family
EGX68_RS08670	COG2391	methyltransferase activity
EGX68_RS08675	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EGX68_RS08680	COG0488	(ABC) transporter
EGX68_RS08685	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EGX68_RS08695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EGX68_RS08700	COG0456	acetyltransferase
EGX68_RS08705	COG1214	PFAM Peptidase M22, glycoprotease
EGX68_RS08710	COG0802	atpase or kinase
EGX68_RS08715	COG0129	dihydroxy-acid dehydratase activity
EGX68_RS08720	COG0028	Belongs to the TPP enzyme family
EGX68_RS08725	COG0440	acetolactate synthase activity
EGX68_RS08730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EGX68_RS08735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGX68_RS08740	COG0473	3-isopropylmalate dehydrogenase activity
EGX68_RS08745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGX68_RS08750	COG0066	3-isopropylmalate dehydratase activity
EGX68_RS08755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGX68_RS08785	COG3091	SprT-like family
EGX68_RS08790	COG2183	response to ionizing radiation
EGX68_RS08795	COG1191	sigma factor activity
EGX68_RS08810	COG2208	phosphoserine phosphatase activity
EGX68_RS08815	COG2337	Toxic component of a toxin-antitoxin (TA) module
EGX68_RS08825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGX68_RS08835	COG3402	PFAM membrane-flanked domain
EGX68_RS08840	COG3428	Bacterial PH domain
EGX68_RS08850	COG0513	Belongs to the DEAD box helicase family
EGX68_RS08855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGX68_RS08860	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGX68_RS08865	COG0772	Belongs to the SEDS family
EGX68_RS08880	COG1937	Protein conserved in bacteria
EGX68_RS08890	COG1418	mRNA catabolic process
EGX68_RS08895	COG0706	membrane insertase activity
EGX68_RS08900	COG0352	thiamine-phosphate diphosphorylase activity
EGX68_RS08905	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EGX68_RS08915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EGX68_RS08920	COG1388	LysM domain
EGX68_RS08925	COG0629	single-stranded DNA binding
EGX68_RS08935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGX68_RS08940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGX68_RS08950	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EGX68_RS08955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EGX68_RS08960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EGX68_RS08965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EGX68_RS08970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGX68_RS08975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EGX68_RS08980	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGX68_RS08985	COG0356	it plays a direct role in the translocation of protons across the membrane
EGX68_RS08995	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGX68_RS09000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EGX68_RS09005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGX68_RS09010	COG4475	Protein of unknown function (DUF436)
EGX68_RS09015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX68_RS09020	COG0009	L-threonylcarbamoyladenylate synthase
EGX68_RS09025	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX68_RS09030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EGX68_RS09035	COG1435	thymidine kinase activity
EGX68_RS09040	COG0254	rRNA binding
EGX68_RS09045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGX68_RS09065	COG1012	belongs to the aldehyde dehydrogenase family
EGX68_RS09075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGX68_RS09080	COG0191	fructose-bisphosphate aldolase activity
EGX68_RS09090	COG0504	CTP synthase activity
EGX68_RS09095	COG3343	RNA polymerase activity
EGX68_RS09100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX68_RS09110	COG5146	pantothenate kinase activity
EGX68_RS09130	COG1854	S-ribosylhomocysteine lyase activity
EGX68_RS09140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EGX68_RS09145	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EGX68_RS09150	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGX68_RS09160	COG0783	Belongs to the Dps family
EGX68_RS09165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX68_RS09180	COG2855	membrane
EGX68_RS09190	COG1482	cell wall glycoprotein biosynthetic process
EGX68_RS09195	COG2186	Transcriptional regulator
EGX68_RS09200	COG0702	epimerase
EGX68_RS09205	COG0640	Transcriptional regulator
EGX68_RS09225	COG0561	phosphatase activity
EGX68_RS09230	COG1119	ATPase activity
EGX68_RS09245	COG2213	PTS system mannitol-specific
EGX68_RS09250	COG3711	transcriptional antiterminator
EGX68_RS09260	COG0246	Mannitol dehydrogenase
EGX68_RS09265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGX68_RS09275	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EGX68_RS09330	COG0489	protein tyrosine kinase activity
EGX68_RS09345	COG1272	protein, Hemolysin III
EGX68_RS09350	COG4284	Utp--glucose-1-phosphate uridylyltransferase
EGX68_RS09355	COG1988	membrane-bound metal-dependent
EGX68_RS09365	COG2329	Antibiotic biosynthesis monooxygenase
EGX68_RS09370	COG3314	Sporulation integral membrane protein YlbJ
EGX68_RS09375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX68_RS09380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX68_RS09385	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EGX68_RS09395	COG4264	IucA IucC family
EGX68_RS09400	COG2814	Major facilitator Superfamily
EGX68_RS09405	COG4264	IucA IucC family
EGX68_RS09410	COG1302	Protein conserved in bacteria
EGX68_RS09425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX68_RS09430	COG0604	alcohol dehydrogenase
EGX68_RS09435	COG2130	NADP-dependent
EGX68_RS09440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX68_RS09455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EGX68_RS09460	COG0101	tRNA pseudouridine synthase activity
EGX68_RS09470	COG1122	ATPase activity
EGX68_RS09475	COG1122	ATPase activity
EGX68_RS09480	COG0203	ribosomal protein L17
EGX68_RS09485	COG0202	RNA polymerase activity
EGX68_RS09495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EGX68_RS09500	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX68_RS09510	COG0563	adenylate kinase activity
EGX68_RS09515	COG0201	protein transport
EGX68_RS09520	COG0200	Binds to the 23S rRNA
EGX68_RS09525	COG1841	ribosomal large subunit assembly
EGX68_RS09530	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EGX68_RS09535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EGX68_RS09540	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EGX68_RS09545	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EGX68_RS09550	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGX68_RS09555	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EGX68_RS09560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EGX68_RS09565	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGX68_RS09570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGX68_RS09575	COG0255	Belongs to the universal ribosomal protein uL29 family
EGX68_RS09580	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGX68_RS09585	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EGX68_RS09590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EGX68_RS09595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGX68_RS09600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EGX68_RS09605	COG0089	rRNA binding
EGX68_RS09610	COG0088	Forms part of the polypeptide exit tunnel
EGX68_RS09615	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EGX68_RS09620	COG0051	transcription antitermination factor activity, RNA binding
EGX68_RS09630	COG2252	PERMEase
EGX68_RS09635	COG0551	DNA topoisomerase type I activity
EGX68_RS09635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX68_RS09645	COG4975	Glucose uptake
EGX68_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
EGX68_RS09675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX68_RS09680	COG2348	transferase activity, transferring amino-acyl groups
EGX68_RS09700	COG2814	Major facilitator Superfamily
EGX68_RS09710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGX68_RS09715	COG0746	molybdenum cofactor guanylyltransferase activity
EGX68_RS09730	COG1763	Mo-molybdopterin cofactor biosynthetic process
EGX68_RS09740	COG0315	cyclic pyranopterin monophosphate synthase activity
EGX68_RS09745	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGX68_RS09750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGX68_RS09765	COG4149	molybdate abc transporter
EGX68_RS09770	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGX68_RS09775	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EGX68_RS09780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGX68_RS09785	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EGX68_RS09790	COG1609	Transcriptional regulator
EGX68_RS09795	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EGX68_RS09805	COG1268	BioY protein
EGX68_RS09810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX68_RS09815	COG1960	acyl-CoA dehydrogenase activity
EGX68_RS09820	COG1126	abc transporter atp-binding protein
EGX68_RS09830	COG0765	amino acid transport
EGX68_RS09835	COG0765	amino acid transport
EGX68_RS09860	COG3942	CHAP domain
EGX68_RS09865	COG1757	Na H antiporter
EGX68_RS09885	COG2076	Multidrug Resistance protein
EGX68_RS09890	COG2076	Multidrug Resistance protein
EGX68_RS09895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX68_RS09920	COG3383	formate dehydrogenase (NAD+) activity
EGX68_RS09925	COG1316	TRANSCRIPTIONal
EGX68_RS09955	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EGX68_RS09960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX68_RS09960	COG1263	PTS System
EGX68_RS09965	COG1737	Transcriptional regulator
EGX68_RS09970	COG1785	Belongs to the alkaline phosphatase family
EGX68_RS09975	COG1113	amino acid transport
EGX68_RS10000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX68_RS10005	COG0385	Bile acid
EGX68_RS10015	COG1263	PTS System
EGX68_RS10015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX68_RS10020	COG1737	Transcriptional regulator
EGX68_RS10035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGX68_RS10040	COG1028	Short-chain dehydrogenase reductase Sdr
EGX68_RS10045	COG1473	amidohydrolase
EGX68_RS10050	COG0659	secondary active sulfate transmembrane transporter activity
EGX68_RS10055	COG1228	amidohydrolase
EGX68_RS10060	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EGX68_RS10065	COG3314	Sporulation integral membrane protein YlbJ
EGX68_RS10070	COG0583	DNA-binding transcription factor activity
EGX68_RS10075	COG0010	Belongs to the arginase family
EGX68_RS10080	COG1266	CAAX protease self-immunity
EGX68_RS10085	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGX68_RS10095	COG2017	converts alpha-aldose to the beta-anomer
EGX68_RS10100	COG1668	transmembrane transport
EGX68_RS10105	COG4152	abc transporter atp-binding protein
EGX68_RS10110	COG1069	ribulokinase activity
EGX68_RS10120	COG2094	Belongs to the DNA glycosylase MPG family
EGX68_RS10125	COG1757	Na H antiporter
EGX68_RS10140	COG1695	Transcriptional regulator
EGX68_RS10145	COG0786	glutamate:sodium symporter activity
EGX68_RS10150	COG1304	FMN binding
EGX68_RS10155	COG0598	Magnesium transport protein CorA
EGX68_RS10180	COG2814	Major facilitator Superfamily
EGX68_RS10185	COG1566	PFAM secretion protein HlyD family protein
EGX68_RS10195	COG2814	Major facilitator Superfamily
EGX68_RS10200	COG4640	response to antibiotic
EGX68_RS10215	COG1136	(ABC) transporter
EGX68_RS10220	COG0577	efflux transmembrane transporter activity
EGX68_RS10225	COG0745	RESPONSE REGULATOR receiver
EGX68_RS10230	COG3850	Histidine kinase
EGX68_RS10230	COG5002	protein histidine kinase activity
EGX68_RS10240	COG0438	transferase activity, transferring glycosyl groups
EGX68_RS10245	COG1620	l-lactate permease
EGX68_RS10250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX68_RS10265	COG0604	alcohol dehydrogenase
EGX68_RS10270	COG2814	Major facilitator Superfamily
EGX68_RS10300	COG0492	ferredoxin-NADP+ reductase activity
EGX68_RS10320	COG0698	ribose 5-phosphate isomerase
EGX68_RS10335	COG1063	alcohol dehydrogenase
EGX68_RS10340	COG1349	DNA-binding transcription factor activity
EGX68_RS10345	COG1288	antiporter activity
EGX68_RS10350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX68_RS10355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX68_RS10360	COG1283	sodium-dependent phosphate transmembrane transporter activity
EGX68_RS10395	COG1846	Transcriptional regulator
EGX68_RS10400	COG0071	Belongs to the small heat shock protein (HSP20) family
EGX68_RS10415	COG0454	-acetyltransferase
EGX68_RS10420	COG2116	formate transmembrane transporter activity
EGX68_RS10440	COG3443	Belongs to the bacterial solute-binding protein 9 family
EGX68_RS10440	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX68_RS10445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX68_RS10460	COG2814	Major facilitator Superfamily
EGX68_RS10470	COG0588	phosphoglycerate mutase activity
EGX68_RS10475	COG1388	LysM domain
EGX68_RS10480	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EGX68_RS10490	COG2814	Major facilitator Superfamily
EGX68_RS10505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGX68_RS10510	COG0706	membrane insertase activity
EGX68_RS10520	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EGX68_RS10540	COG4187	Peptidase family M20/M25/M40
EGX68_RS10550	COG3275	phosphorelay sensor kinase activity
EGX68_RS10555	COG3279	Response regulator of the LytR AlgR family
EGX68_RS10565	COG1346	cytolysis
EGX68_RS10575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGX68_RS10575	COG1116	anion transmembrane transporter activity
EGX68_RS10585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX68_RS10610	COG1174	glycine betaine transport
EGX68_RS10620	COG1174	glycine betaine transport
EGX68_RS10635	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGX68_RS10640	COG3246	L-lysine catabolic process to acetate
EGX68_RS10650	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EGX68_RS10655	COG2851	Citrate transporter
EGX68_RS10660	COG2814	Major facilitator Superfamily
EGX68_RS10665	COG0390	transport system, permease component
EGX68_RS10670	COG4619	ABC transporter
EGX68_RS10680	COG0069	glutamate synthase activity
EGX68_RS10690	COG1363	Peptidase, m42
EGX68_RS10695	COG1028	Short-chain dehydrogenase reductase Sdr
EGX68_RS10705	COG0248	Ppx GppA phosphatase
EGX68_RS10710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGX68_RS10715	COG3048	D-serine ammonia-lyase activity
EGX68_RS10725	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EGX68_RS10730	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGX68_RS10735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGX68_RS10740	COG0131	Imidazoleglycerol-phosphate dehydratase
EGX68_RS10745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGX68_RS10750	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EGX68_RS10755	COG0107	imidazoleglycerol-phosphate synthase activity
EGX68_RS10770	COG4221	oxidoreductase activity
EGX68_RS10800	COG3250	beta-galactosidase activity
EGX68_RS10805	COG2211	Major facilitator Superfamily
EGX68_RS10810	COG2207	Transcriptional regulator
EGX68_RS10815	COG3949	Membrane
EGX68_RS10820	COG2610	gluconate transmembrane transporter activity
EGX68_RS10825	COG1070	Carbohydrate kinase
EGX68_RS10830	COG1802	Transcriptional regulator
EGX68_RS10840	COG2357	RelA SpoT domain protein
EGX68_RS10845	COG4876	unkown
EGX68_RS10865	COG3527	Alpha-acetolactate decarboxylase
EGX68_RS10885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX68_RS10890	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EGX68_RS10895	COG3949	Membrane
EGX68_RS10900	COG0400	carboxylic ester hydrolase activity
EGX68_RS10905	COG0346	lactoylglutathione lyase activity
EGX68_RS10910	COG0346	lactoylglutathione lyase activity
EGX68_RS10915	COG1846	Transcriptional regulator
EGX68_RS10925	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX68_RS10935	COG1132	(ABC) transporter
EGX68_RS10945	COG2514	catechol 2,3-dioxygenase activity
EGX68_RS10950	COG0778	Nitroreductase
EGX68_RS10955	COG0561	phosphatase activity
EGX68_RS10965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX68_RS10975	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGX68_RS10980	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EGX68_RS10985	COG3764	Sortase (surface protein transpeptidase)
EGX68_RS11005	COG1063	alcohol dehydrogenase
EGX68_RS11010	COG1070	Carbohydrate kinase
EGX68_RS11020	COG1609	Transcriptional regulator
EGX68_RS11030	COG1129	ABC transporter
EGX68_RS11050	COG3949	Membrane
EGX68_RS11070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGX68_RS11080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGX68_RS11085	COG0657	acetylesterase activity
EGX68_RS11100	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EGX68_RS11110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX68_RS11115	COG1288	antiporter activity
EGX68_RS11120	COG0028	Belongs to the TPP enzyme family
EGX68_RS11135	COG0583	DNA-binding transcription factor activity
EGX68_RS11140	COG1757	Na H antiporter
EGX68_RS11145	COG3386	PFAM SMP-30 Gluconolaconase
EGX68_RS11160	COG3425	synthase
EGX68_RS11165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX68_RS11170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX68_RS11185	COG1473	amidohydrolase
EGX68_RS11200	COG2409	Drug exporters of the RND superfamily
EGX68_RS11210	COG1012	belongs to the aldehyde dehydrogenase family
EGX68_RS11225	COG4336	lyase activity
EGX68_RS11240	COG5505	Protein of unknown function (DUF819)
EGX68_RS11245	COG0471	metal ion transport
EGX68_RS11255	COG1028	Short-chain dehydrogenase reductase Sdr
EGX68_RS11260	COG0577	efflux transmembrane transporter activity
EGX68_RS11265	COG1136	(ABC) transporter
EGX68_RS11270	COG0659	secondary active sulfate transmembrane transporter activity
EGX68_RS11275	COG2217	Heavy metal translocating P-type atpase
EGX68_RS11280	COG2608	mercury ion transmembrane transporter activity
EGX68_RS11290	COG0436	Aminotransferase
EGX68_RS11295	COG1388	LysM domain
EGX68_RS11310	COG3189	MarR family transcriptional regulator
EGX68_RS11330	COG0697	spore germination
EGX68_RS11355	COG3001	Fructosamine kinase
EGX68_RS11360	COG0167	dihydroorotate dehydrogenase activity
EGX68_RS11370	COG0561	phosphatase activity
EGX68_RS11385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX68_RS11410	COG0747	negative chemotaxis
EGX68_RS11415	COG4413	Urea transporter
EGX68_RS11420	COG0831	urea catabolic process
EGX68_RS11425	COG0832	Belongs to the urease beta subunit family
EGX68_RS11430	COG0804	urea catabolic process
EGX68_RS11435	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EGX68_RS11440	COG0830	nickel cation binding
EGX68_RS11445	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EGX68_RS11450	COG0829	nickel cation binding
EGX68_RS11460	COG3949	Membrane
EGX68_RS11470	COG1309	transcriptional regulator
EGX68_RS11485	COG1309	transcriptional regulator
EGX68_RS11515	COG1482	cell wall glycoprotein biosynthetic process
EGX68_RS11520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX68_RS11520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX68_RS11520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX68_RS11530	COG0039	L-malate dehydrogenase activity
EGX68_RS11535	COG1464	Belongs to the NlpA lipoprotein family
EGX68_RS11550	COG1028	Short-chain dehydrogenase reductase Sdr
EGX68_RS11560	COG1956	GAF domain-containing protein
EGX68_RS11570	COG1028	Short-chain dehydrogenase reductase Sdr
EGX68_RS11575	COG0302	gtp cyclohydrolase
EGX68_RS11580	COG1794	racemase activity, acting on amino acids and derivatives
EGX68_RS11590	COG3226	Transcriptional regulator
EGX68_RS11595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGX68_RS11605	COG3037	sugar-specific permease SgaT UlaA
EGX68_RS11615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX68_RS11620	COG3711	transcriptional antiterminator
EGX68_RS11655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX68_RS11670	COG0363	glucosamine-6-phosphate deaminase activity
EGX68_RS11690	COG1620	l-lactate permease
EGX68_RS11700	COG0431	NADPH-dependent FMN reductase
EGX68_RS11705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGX68_RS11710	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGX68_RS11725	COG2610	gluconate transmembrane transporter activity
EGX68_RS11730	COG1131	(ABC) transporter
EGX68_RS11750	COG0477	Major facilitator Superfamily
EGX68_RS11755	COG1957	nucleoside hydrolase
EGX68_RS11760	COG2843	Capsule synthesis protein
EGX68_RS11765	COG0778	Nitroreductase
EGX68_RS11770	COG0463	Glycosyl transferase, family 2
EGX68_RS11770	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX68_RS11775	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EGX68_RS11780	COG1012	belongs to the aldehyde dehydrogenase family
EGX68_RS11785	COG1510	regulation of RNA biosynthetic process
EGX68_RS11790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX68_RS11800	COG3588	fructose-bisphosphate aldolase
EGX68_RS11810	COG0531	amino acid
EGX68_RS11815	COG1012	belongs to the aldehyde dehydrogenase family
EGX68_RS11820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGX68_RS11825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX68_RS11835	COG2807	transmembrane transport
EGX68_RS11840	COG1476	TRANSCRIPTIONal
EGX68_RS11865	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EGX68_RS11870	COG0574	Belongs to the PEP-utilizing enzyme family
EGX68_RS11870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX68_RS11875	COG3835	regulator
EGX68_RS11890	COG0673	inositol 2-dehydrogenase activity
EGX68_RS11915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX68_RS11930	COG3961	Belongs to the TPP enzyme family
EGX68_RS11935	COG1846	Transcriptional regulator
EGX68_RS11940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGX68_RS11955	COG0584	glycerophosphoryl diester phosphodiesterase
EGX68_RS11970	COG2814	Major facilitator Superfamily
EGX68_RS11985	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EGX68_RS11995	COG1328	CTP reductase activity
EGX68_RS12000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGX68_RS12005	COG2022	thiamine diphosphate biosynthetic process
EGX68_RS12020	COG1070	Carbohydrate kinase
EGX68_RS12030	COG1917	Cupin 2, conserved barrel domain protein
EGX68_RS12030	COG2207	Transcriptional regulator
EGX68_RS12045	COG1511	domain protein
EGX68_RS12045	COG1511	domain protein
EGX68_RS12055	COG1228	amidohydrolase
EGX68_RS12070	COG1054	Belongs to the UPF0176 family
EGX68_RS12075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGX68_RS12080	COG1388	LysM domain
EGX68_RS12130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGX68_RS12135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX68_RS12140	COG1388	LysM domain
EGX68_RS12145	COG1388	LysM domain
EGX68_RS12170	COG0730	response to heat
EGX68_RS12175	COG1937	Protein conserved in bacteria
EGX68_RS12180	COG2210	Belongs to the sulfur carrier protein TusA family
EGX68_RS12185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX68_RS12215	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EGX68_RS12220	COG0785	Cytochrome C biogenesis protein
EGX68_RS12255	COG0640	Transcriptional regulator
EGX68_RS12275	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX68_RS12285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX68_RS12290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX68_RS12300	COG0659	secondary active sulfate transmembrane transporter activity
EGX68_RS12305	COG0589	response to stress
EGX68_RS12335	COG0706	membrane insertase activity
EGX68_RS12350	COG3093	addiction module antidote protein HigA
EGX68_RS12370	COG1733	regulation of RNA biosynthetic process
EGX68_RS12385	COG0583	DNA-binding transcription factor activity
EGX68_RS12390	COG1607	acyl-coa hydrolase
EGX68_RS12400	COG1063	alcohol dehydrogenase
EGX68_RS12455	COG0583	DNA-binding transcription factor activity
EGX68_RS12475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX68_RS12520	COG1388	LysM domain
EGX68_RS12525	COG0564	pseudouridine synthase activity
EGX68_RS12530	COG1388	LysM domain
EGX68_RS12535	COG2318	DinB family
EGX68_RS12540	COG0471	metal ion transport
EGX68_RS12545	COG1028	Short-chain dehydrogenase reductase Sdr
EGX68_RS12550	COG0579	oxidoreductase
EGX68_RS12565	COG3655	Transcriptional regulator
EGX68_RS12575	COG1511	domain protein
EGX68_RS12585	COG0640	Transcriptional regulator
EGX68_RS12595	COG3711	transcriptional antiterminator
EGX68_RS12605	COG2723	6-phospho-beta-galactosidase activity
EGX68_RS12610	COG2723	6-phospho-beta-galactosidase activity
EGX68_RS12615	COG0402	S-adenosylhomocysteine deaminase activity
EGX68_RS12625	COG1876	peptidase activity
EGX68_RS12630	COG0438	transferase activity, transferring glycosyl groups
EGX68_RS12715	COG0702	epimerase
EGX68_RS12725	COG0789	Transcriptional regulator
EGX68_RS12785	COG1620	l-lactate permease
EGX68_RS12790	COG3527	Alpha-acetolactate decarboxylase
EGX68_RS12795	COG0028	Belongs to the TPP enzyme family
EGX68_RS12800	COG0579	oxidoreductase
EGX68_RS12870	COG2801	Transposase and inactivated derivatives
EGX68_RS12900	COG1316	TRANSCRIPTIONal
EGX68_RS12905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGX68_RS12910	COG0110	maltose O-acetyltransferase activity
EGX68_RS12915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGX68_RS12935	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGX68_RS12985	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EGX68_RS12995	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EGX68_RS13055	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EGX68_RS13060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGX68_RS13075	COG5002	protein histidine kinase activity
EGX68_RS13080	COG0745	RESPONSE REGULATOR receiver
EGX68_RS13085	COG0477	Major facilitator Superfamily
EGX68_RS13110	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGX68_RS13115	COG0305	Participates in initiation and elongation during chromosome replication
EGX68_RS13120	COG0359	binds to the 23S rRNA
EGX68_RS13125	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EGX68_RS13135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGX68_RS13145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGX68_RS13150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EGX68_RS13155	COG2986	histidine ammonia-lyase
EGX68_RS13160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGX68_RS13170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX68_RS13175	COG0187	DNA topoisomerase II activity
EGX68_RS13180	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGX68_RS13185	COG2501	S4 domain
EGX68_RS13190	COG0592	DNA-directed DNA polymerase activity
EGX68_RS13195	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGX68_RS13205	COG0594	ribonuclease P activity
EGX68_RS13210	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EGX68_RS13220	COG0357	Ribosomal RNA small subunit methyltransferase G
EGX68_RS13225	COG1475	DNA binding
EGX68_RS13230	COG1966	Carbon starvation protein
EGX68_RS13240	COG2271	Major facilitator Superfamily
EGX68_RS13275	COG0531	amino acid
EGX68_RS13295	COG0384	phenazine biosynthesis protein PhzF
EGX68_RS13310	COG0789	Transcriptional regulator
EGX68_RS13320	COG0318	PFAM AMP-dependent synthetase and ligase
EGX68_RS13325	COG1960	acyl-CoA dehydrogenase activity
EGX68_RS13330	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGX68_RS13330	COG1024	Enoyl-CoA hydratase
EGX68_RS13335	COG0183	Belongs to the thiolase family
EGX68_RS13355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGX68_RS13365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EGX68_RS13370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EGX68_RS13370	COG0646	methionine synthase
EGX68_RS13375	COG0626	cystathionine gamma-synthase activity
EGX68_RS13380	COG0626	cystathionine gamma-synthase activity