locus-tag	class	description
BZ166_RS00015	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BZ166_RS00020	COG0564	pseudouridine synthase activity
BZ166_RS00040	COG3599	regulation of cell shape
BZ166_RS00050	COG0762	integral membrane protein
BZ166_RS00060	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BZ166_RS00065	COG1496	oxidoreductase activity
BZ166_RS00070	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BZ166_RS00075	COG0849	cell division
BZ166_RS00080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BZ166_RS00085	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BZ166_RS00095	COG0768	penicillin binding
BZ166_RS00100	COG4839	cell division protein FtsL
BZ166_RS00110	COG2001	Belongs to the MraZ family
BZ166_RS00115	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BZ166_RS00120	COG0454	-acetyltransferase
BZ166_RS00125	COG1011	Hydrolase
BZ166_RS00160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BZ166_RS00165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BZ166_RS00170	COG1053	succinate dehydrogenase
BZ166_RS00175	COG2009	succinate dehydrogenase
BZ166_RS00185	COG3118	belongs to the thioredoxin family
BZ166_RS00195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BZ166_RS00195	COG1796	DNA polymerase
BZ166_RS00205	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BZ166_RS00210	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BZ166_RS00215	COG0072	phenylalanine-tRNA ligase activity
BZ166_RS00220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BZ166_RS00225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ166_RS00235	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BZ166_RS00245	COG1323	Belongs to the UPF0348 family
BZ166_RS00255	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BZ166_RS00260	COG0742	ribosomal rna small subunit methyltransferase
BZ166_RS00270	COG4471	UPF0298 protein
BZ166_RS00280	COG3679	Belongs to the UPF0342 family
BZ166_RS00305	COG1612	heme a metabolic process
BZ166_RS00315	COG0772	Belongs to the SEDS family
BZ166_RS00320	COG4838	Belongs to the UPF0358 family
BZ166_RS00325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BZ166_RS00330	COG4896	Protein conserved in bacteria
BZ166_RS00335	COG1217	gtp-binding protein TYPA
BZ166_RS00345	COG0483	inositol monophosphate 1-phosphatase activity
BZ166_RS00350	COG4493	Belongs to the UPF0637 family
BZ166_RS00360	COG1914	H( )-stimulated, divalent metal cation uptake system
BZ166_RS00375	COG1177	transmembrane transport
BZ166_RS00395	COG4476	Belongs to the UPF0223 family
BZ166_RS00425	COG0242	peptide deformylase activity
BZ166_RS00435	COG5503	Protein of unknown function (DUF1447)
BZ166_RS00440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BZ166_RS00445	COG0569	domain protein
BZ166_RS00450	COG1294	oxidase, subunit
BZ166_RS00470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ166_RS00495	COG4172	Belongs to the ABC transporter superfamily
BZ166_RS00500	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BZ166_RS00540	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BZ166_RS00545	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BZ166_RS00550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BZ166_RS00555	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BZ166_RS00570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BZ166_RS00585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BZ166_RS00600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BZ166_RS00605	COG1316	TRANSCRIPTIONal
BZ166_RS00630	COG3594	Acyltransferase
BZ166_RS00635	COG0436	Aminotransferase
BZ166_RS00650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BZ166_RS00655	COG2267	carboxylic ester hydrolase activity
BZ166_RS00660	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BZ166_RS00670	COG1575	Belongs to the MenA family. Type 1 subfamily
BZ166_RS00680	COG2314	TM2 domain
BZ166_RS00700	COG4903	ComK protein
BZ166_RS00715	COG4873	Protein conserved in bacteria
BZ166_RS00725	COG0737	Belongs to the 5'-nucleotidase family
BZ166_RS00735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ166_RS00740	COG0861	Integral membrane protein TerC family
BZ166_RS00755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BZ166_RS00760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BZ166_RS00765	COG2814	Major facilitator Superfamily
BZ166_RS00770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BZ166_RS00800	COG2239	Acts as a magnesium transporter
BZ166_RS00805	COG0564	pseudouridine synthase activity
BZ166_RS00810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BZ166_RS00815	COG2357	RelA SpoT domain protein
BZ166_RS00825	COG4116	CYTH
BZ166_RS00835	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BZ166_RS00840	COG1164	Oligoendopeptidase f
BZ166_RS00850	COG4862	establishment of competence for transformation
BZ166_RS00855	COG1393	Belongs to the ArsC family
BZ166_RS00860	COG0180	Tryptophanyl-tRNA synthetase
BZ166_RS00880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ166_RS00885	COG0601	transmembrane transport
BZ166_RS00905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BZ166_RS00935	COG0561	phosphatase activity
BZ166_RS00940	COG0446	pyridine nucleotide-disulphide oxidoreductase
BZ166_RS00950	COG0179	Fumarylacetoacetate (FAA) hydrolase
BZ166_RS00955	COG2311	Membrane
BZ166_RS00965	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BZ166_RS00980	COG0398	Pfam SNARE associated Golgi protein
BZ166_RS00985	COG0166	Belongs to the GPI family
BZ166_RS00990	COG0137	argininosuccinate synthase activity
BZ166_RS00995	COG0165	Argininosuccinate lyase
BZ166_RS01015	COG0584	glycerophosphoryl diester phosphodiesterase
BZ166_RS01025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BZ166_RS01030	COG1902	pentaerythritol trinitrate reductase activity
BZ166_RS01035	COG1098	S1 RNA binding domain
BZ166_RS01040	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZ166_RS01055	COG2111	Na H antiporter
BZ166_RS01060	COG1006	Multisubunit Na H antiporter MnhC subunit
BZ166_RS01065	COG0651	ATP synthesis coupled electron transport
BZ166_RS01070	COG2212	antiporter activity
BZ166_RS01075	COG1320	monovalent cation:proton antiporter activity
BZ166_RS01095	COG2056	Na+-H+ antiporter family
BZ166_RS01105	COG1252	NADH dehydrogenase
BZ166_RS01110	COG0316	Belongs to the HesB IscA family
BZ166_RS01115	COG4844	belongs to the
BZ166_RS01120	COG1252	NADH dehydrogenase
BZ166_RS01125	COG4837	Protein of unknown function (DUF1462)
BZ166_RS01130	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BZ166_RS01140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BZ166_RS01145	COG1696	Membrane protein involved in D-alanine export
BZ166_RS01165	COG0647	UMP catabolic process
BZ166_RS01170	COG2445	Protein of unknown function DUF86
BZ166_RS01180	COG4470	Protein conserved in bacteria
BZ166_RS01190	COG0737	Belongs to the 5'-nucleotidase family
BZ166_RS01195	COG0730	response to heat
BZ166_RS01200	COG1801	Protein of unknown function DUF72
BZ166_RS01205	COG2070	2-Nitropropane dioxygenase
BZ166_RS01210	COG1253	flavin adenine dinucleotide binding
BZ166_RS01220	COG0822	iron-sulfur transferase activity
BZ166_RS01230	COG0719	Fe-S assembly protein
BZ166_RS01235	COG0396	ATPase activity
BZ166_RS01245	COG1464	Belongs to the NlpA lipoprotein family
BZ166_RS01250	COG2011	ABC-type metal ion transport system permease component
BZ166_RS01255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BZ166_RS01260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZ166_RS01265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BZ166_RS01270	COG0509	glycine decarboxylation via glycine cleavage system
BZ166_RS01280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZ166_RS01285	COG0778	Nitroreductase
BZ166_RS01295	COG1764	response to oxidative stress
BZ166_RS01325	COG2314	TM2 domain
BZ166_RS01360	COG0346	lactoylglutathione lyase activity
BZ166_RS01385	COG1288	antiporter activity
BZ166_RS01405	COG0584	glycerophosphoryl diester phosphodiesterase
BZ166_RS01465	COG2329	Antibiotic biosynthesis monooxygenase
BZ166_RS01480	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BZ166_RS01485	COG0557	exoribonuclease II activity
BZ166_RS01490	COG1647	Serine aminopeptidase, S33
BZ166_RS01495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZ166_RS01505	COG0148	phosphopyruvate hydratase activity
BZ166_RS01515	COG0149	triose-phosphate isomerase activity
BZ166_RS01520	COG0126	phosphoglycerate kinase activity
BZ166_RS01525	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BZ166_RS01550	COG1090	epimerase
BZ166_RS01560	COG0740	serine-type endopeptidase activity
BZ166_RS01695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BZ166_RS01705	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BZ166_RS01710	COG1660	Displays ATPase and GTPase activities
BZ166_RS01715	COG0492	ferredoxin-NADP+ reductase activity
BZ166_RS01725	COG0110	maltose O-acetyltransferase activity
BZ166_RS01730	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BZ166_RS01735	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BZ166_RS01745	COG0556	nucleotide-excision repair
BZ166_RS01765	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BZ166_RS01770	COG0653	protein targeting
BZ166_RS01775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BZ166_RS01795	COG1739	Uncharacterized protein family UPF0029
BZ166_RS01800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BZ166_RS01805	COG2199	diguanylate cyclase activity
BZ166_RS01825	COG1929	Belongs to the glycerate kinase type-1 family
BZ166_RS01860	COG4607	ABC-type enterochelin transport system periplasmic component
BZ166_RS01865	COG4604	ABC transporter, ATP-binding protein
BZ166_RS01870	COG4605	iron ion homeostasis
BZ166_RS01880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZ166_RS01890	COG1780	Probably involved in ribonucleotide reductase function
BZ166_RS01905	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BZ166_RS01915	COG3104	oligopeptide transport
BZ166_RS01920	COG1597	lipid kinase activity
BZ166_RS01930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BZ166_RS01935	COG1174	glycine betaine transport
BZ166_RS01940	COG0517	IMP dehydrogenase activity
BZ166_RS01940	COG1125	glycine betaine transport
BZ166_RS01960	COG1368	sulfuric ester hydrolase activity
BZ166_RS01990	COG0512	Glutamine amidotransferase of anthranilate synthase
BZ166_RS01990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BZ166_RS01995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BZ166_RS02000	COG0720	synthase
BZ166_RS02005	COG0602	queuosine metabolic process
BZ166_RS02020	COG0463	Glycosyl transferase, family 2
BZ166_RS02025	COG0656	L-ascorbic acid biosynthetic process
BZ166_RS02030	COG1253	flavin adenine dinucleotide binding
BZ166_RS02055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BZ166_RS02090	COG0039	L-malate dehydrogenase activity
BZ166_RS02095	COG0586	Pfam SNARE associated Golgi protein
BZ166_RS02105	COG4989	oxidoreductase activity
BZ166_RS02110	COG0523	cobalamin synthesis protein
BZ166_RS02120	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BZ166_RS02125	COG4988	ABC transporter
BZ166_RS02130	COG1968	undecaprenyl-diphosphatase activity
BZ166_RS02140	COG1671	Belongs to the UPF0178 family
BZ166_RS02145	COG1611	Belongs to the LOG family
BZ166_RS02150	COG1279	arginine transmembrane transporter activity
BZ166_RS02185	COG2814	Major facilitator Superfamily
BZ166_RS02190	COG2839	Protein conserved in bacteria
BZ166_RS02200	COG0583	DNA-binding transcription factor activity
BZ166_RS02210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BZ166_RS02220	COG0217	transcriptional regulatory protein
BZ166_RS02240	COG1388	LysM domain
BZ166_RS02240	COG3942	CHAP domain
BZ166_RS02245	COG0306	phosphate transporter
BZ166_RS02250	COG1392	Phosphate transport regulator
BZ166_RS02255	COG2205	protein histidine kinase activity
BZ166_RS02260	COG0745	RESPONSE REGULATOR receiver
BZ166_RS02275	COG0657	acetylesterase activity
BZ166_RS02280	COG3949	Membrane
BZ166_RS02295	COG1461	Dihydroxyacetone kinase
BZ166_RS02315	COG1120	ATPase activity
BZ166_RS02320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BZ166_RS02330	COG1132	(ABC) transporter
BZ166_RS02340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BZ166_RS02350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BZ166_RS02355	COG1682	transport, permease protein
BZ166_RS02360	COG1134	teichoic acid transport
BZ166_RS02365	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BZ166_RS02375	COG1321	iron dependent repressor
BZ166_RS02380	COG1121	(ABC) transporter
BZ166_RS02385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ166_RS02400	COG1320	monovalent cation:proton antiporter activity
BZ166_RS02415	COG0651	ATP synthesis coupled electron transport
BZ166_RS02420	COG1006	Multisubunit Na H antiporter MnhC subunit
BZ166_RS02425	COG2111	Na H antiporter
BZ166_RS02430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BZ166_RS02430	COG2111	Na H antiporter
BZ166_RS02495	COG4139	cobalamin transport
BZ166_RS02500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZ166_RS02505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BZ166_RS02510	COG0018	arginyl-trna synthetase
BZ166_RS02530	COG0456	acetyltransferase
BZ166_RS02540	COG0667	Aldo Keto reductase
BZ166_RS02565	COG4844	belongs to the
BZ166_RS02580	COG0083	homoserine kinase activity
BZ166_RS02585	COG0095	Lipoate-protein ligase
BZ166_RS02590	COG0280	phosphate acetyltransferase
BZ166_RS02595	COG3253	May function as heme-dependent peroxidase
BZ166_RS02615	COG2363	Small membrane protein
BZ166_RS02625	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BZ166_RS02660	COG0183	Belongs to the thiolase family
BZ166_RS02675	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BZ166_RS02680	COG0363	glucosamine-6-phosphate deaminase activity
BZ166_RS02690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BZ166_RS02695	COG1469	GTP cyclohydrolase I activity
BZ166_RS02710	COG0431	NADPH-dependent FMN reductase
BZ166_RS02715	COG0561	phosphatase activity
BZ166_RS02725	COG1428	Deoxynucleoside kinase
BZ166_RS02745	COG4297	protein containing double-stranded beta helix domain
BZ166_RS02750	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZ166_RS02755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ166_RS02765	COG0583	DNA-binding transcription factor activity
BZ166_RS02770	COG2814	Major facilitator Superfamily
BZ166_RS02790	COG0010	Belongs to the arginase family
BZ166_RS02800	COG3949	Membrane
BZ166_RS02805	COG2271	Major facilitator Superfamily
BZ166_RS02810	COG1233	COG1233 Phytoene dehydrogenase and related
BZ166_RS02815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BZ166_RS02820	COG1012	belongs to the aldehyde dehydrogenase family
BZ166_RS02830	COG1028	Short-chain dehydrogenase reductase Sdr
BZ166_RS02860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ166_RS02930	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BZ166_RS02955	COG1473	amidohydrolase
BZ166_RS02960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BZ166_RS02965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BZ166_RS02970	COG0049	tRNA binding
BZ166_RS02975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BZ166_RS02990	COG0085	RNA polymerase activity
BZ166_RS03000	COG0222	ribosome binding
BZ166_RS03005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BZ166_RS03010	COG0081	regulation of translation
BZ166_RS03015	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BZ166_RS03020	COG0250	Participates in transcription elongation, termination and antitermination
BZ166_RS03025	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZ166_RS03030	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BZ166_RS03045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ166_RS03050	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BZ166_RS03055	COG0215	cysteine-tRNA ligase activity
BZ166_RS03060	COG1045	serine acetyltransferase
BZ166_RS03070	COG4956	integral membrane protein (PIN domain superfamily)
BZ166_RS03075	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BZ166_RS03080	COG0542	response to heat
BZ166_RS03090	COG3880	PFAM UvrB UvrC protein
BZ166_RS03095	COG4463	regulation of RNA biosynthetic process
BZ166_RS03100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZ166_RS03105	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BZ166_RS03110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BZ166_RS03200	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BZ166_RS03205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BZ166_RS03225	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BZ166_RS03240	COG0037	tRNA processing
BZ166_RS03245	COG1098	S1 RNA binding domain
BZ166_RS03255	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BZ166_RS03260	COG3956	TIGRFAM MazG family protein
BZ166_RS03265	COG2244	polysaccharide biosynthetic process
BZ166_RS03275	COG0193	aminoacyl-tRNA hydrolase activity
BZ166_RS03280	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BZ166_RS03285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZ166_RS03295	COG2088	sporulation resulting in formation of a cellular spore
BZ166_RS03300	COG0251	oxidation-reduction process
BZ166_RS03310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BZ166_RS03315	COG4466	Protein conserved in bacteria
BZ166_RS03325	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BZ166_RS03330	COG0084	hydrolase, TatD family'
BZ166_RS03340	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BZ166_RS03345	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BZ166_RS03350	COG4467	Involved in initiation control of chromosome replication
BZ166_RS03360	COG0470	DNA polymerase III
BZ166_RS03365	COG3870	Protein conserved in bacteria
BZ166_RS03375	COG1982	Orn Lys Arg decarboxylase major
BZ166_RS03395	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BZ166_RS03400	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BZ166_RS03405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BZ166_RS03410	COG3153	acetyltransferase
BZ166_RS03420	COG2188	Transcriptional regulator
BZ166_RS03425	COG0366	Alpha amylase catalytic
BZ166_RS03440	COG0493	'glutamate synthase
BZ166_RS03445	COG0067	glutamate synthase
BZ166_RS03445	COG0069	glutamate synthase activity
BZ166_RS03445	COG0070	glutamate synthase
BZ166_RS03450	COG0583	DNA-binding transcription factor activity
BZ166_RS03475	COG1051	belongs to the nudix hydrolase family
BZ166_RS03485	COG3942	CHAP domain
BZ166_RS03485	COG1388	LysM domain
BZ166_RS03495	COG0129	dihydroxy-acid dehydratase activity
BZ166_RS03510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BZ166_RS03515	COG0733	neurotransmitter:sodium symporter activity
BZ166_RS03520	COG1114	Component of the transport system for branched-chain amino acids
BZ166_RS03525	COG5646	InterPro IPR014922
BZ166_RS03530	COG1647	Serine aminopeptidase, S33
BZ166_RS03545	COG0549	Belongs to the carbamate kinase family
BZ166_RS03560	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BZ166_RS03570	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BZ166_RS03575	COG3257	ureidoglycine aminohydrolase activity
BZ166_RS03620	COG2814	Major facilitator Superfamily
BZ166_RS03665	COG1764	response to oxidative stress
BZ166_RS03695	COG0516	GMP reductase activity
BZ166_RS03695	COG0517	IMP dehydrogenase activity
BZ166_RS03700	COG2233	PERMEase
BZ166_RS03705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BZ166_RS03725	COG1823	symporter activity
BZ166_RS03735	COG1760	l-serine dehydratase
BZ166_RS03740	COG1760	l-serine dehydratase
BZ166_RS03765	COG3620	sequence-specific DNA binding
BZ166_RS03770	COG0450	alkyl hydroperoxide reductase
BZ166_RS03775	COG3634	alkyl hydroperoxide reductase activity
BZ166_RS03800	COG1280	lysine exporter protein (LysE YggA)
BZ166_RS03805	COG2076	Multidrug Resistance protein
BZ166_RS03810	COG2076	Multidrug Resistance protein
BZ166_RS03825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ166_RS03845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BZ166_RS03860	COG4193	domain, Protein
BZ166_RS03860	COG5632	N-Acetylmuramoyl-L-alanine amidase
BZ166_RS03860	COG3266	domain, Protein
BZ166_RS03870	COG1476	TRANSCRIPTIONal
BZ166_RS03935	COG0456	acetyltransferase
BZ166_RS03965	COG2176	DNA-directed DNA polymerase activity
BZ166_RS03980	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BZ166_RS03990	COG0360	Binds together with S18 to 16S ribosomal RNA
BZ166_RS04005	COG4481	Protein conserved in bacteria
BZ166_RS04010	COG0668	transmembrane transport
BZ166_RS04015	COG5609	conserved protein (DUF2294)
BZ166_RS04020	COG3002	Belongs to the UPF0753 family
BZ166_RS04040	COG1131	(ABC) transporter
BZ166_RS04050	COG1136	(ABC) transporter
BZ166_RS04065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BZ166_RS04075	COG2814	Major facilitator Superfamily
BZ166_RS04120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BZ166_RS04130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BZ166_RS04140	COG0529	Catalyzes the synthesis of activated sulfate
BZ166_RS04150	COG0730	response to heat
BZ166_RS04165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BZ166_RS04180	COG0175	sulfate reduction
BZ166_RS04200	COG1017	nitric oxide dioxygenase activity
BZ166_RS04200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ166_RS04205	COG1475	DNA binding
BZ166_RS04230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BZ166_RS04240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BZ166_RS04265	COG1024	Enoyl-CoA hydratase
BZ166_RS04265	COG1250	3-hydroxyacyl-CoA dehydrogenase
BZ166_RS04270	COG1960	acyl-CoA dehydrogenase activity
BZ166_RS04285	COG0789	Transcriptional regulator
BZ166_RS04295	COG1028	Short-chain dehydrogenase reductase Sdr
BZ166_RS04310	COG0384	phenazine biosynthesis protein PhzF
BZ166_RS04320	COG0561	phosphatase activity
BZ166_RS04340	COG0531	amino acid
BZ166_RS04375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ166_RS04385	COG2271	Major facilitator Superfamily
BZ166_RS04395	COG1966	Carbon starvation protein
BZ166_RS04400	COG1475	DNA binding
BZ166_RS04405	COG0357	Ribosomal RNA small subunit methyltransferase G
BZ166_RS04410	COG0445	tRNA wobble uridine modification
BZ166_RS04415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BZ166_RS04420	COG0594	ribonuclease P activity
BZ166_RS04430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BZ166_RS04440	COG2501	S4 domain
BZ166_RS04445	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BZ166_RS04455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BZ166_RS04465	COG2986	histidine ammonia-lyase
BZ166_RS04475	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BZ166_RS04485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BZ166_RS04495	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BZ166_RS04500	COG0359	binds to the 23S rRNA
BZ166_RS04505	COG0305	Participates in initiation and elongation during chromosome replication
BZ166_RS04510	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BZ166_RS04515	COG1819	glycosyl
BZ166_RS04535	COG5002	protein histidine kinase activity
BZ166_RS04550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BZ166_RS04555	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BZ166_RS04635	COG0640	Transcriptional regulator
BZ166_RS04655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BZ166_RS04745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BZ166_RS04755	COG4975	Glucose uptake
BZ166_RS04785	COG2160	L-arabinose isomerase activity
BZ166_RS04800	COG1609	Transcriptional regulator
BZ166_RS04820	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BZ166_RS04840	COG1959	2 iron, 2 sulfur cluster binding
BZ166_RS04845	COG2910	NAD(P)H-binding
BZ166_RS04875	COG3942	CHAP domain
BZ166_RS04875	COG1705	Flagellar rod assembly protein muramidase FlgJ
BZ166_RS04895	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BZ166_RS04915	COG0583	DNA-binding transcription factor activity
BZ166_RS04925	COG2814	Major facilitator Superfamily
BZ166_RS04965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZ166_RS04975	COG1447	Phosphotransferase system cellobiose-specific component IIA
BZ166_RS04995	COG1129	ABC transporter
BZ166_RS05030	COG0583	DNA-binding transcription factor activity
BZ166_RS05065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ166_RS05080	COG0471	metal ion transport
BZ166_RS05085	COG1028	Short-chain dehydrogenase reductase Sdr
BZ166_RS05095	COG3711	transcriptional antiterminator
BZ166_RS05105	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BZ166_RS05115	COG0438	transferase activity, transferring glycosyl groups
BZ166_RS05130	COG1686	Belongs to the peptidase S11 family
BZ166_RS05135	COG0402	S-adenosylhomocysteine deaminase activity
BZ166_RS05160	COG2207	Transcriptional regulator
BZ166_RS05170	COG3250	beta-galactosidase activity
BZ166_RS05180	COG3655	Transcriptional regulator
BZ166_RS05200	COG1028	Short-chain dehydrogenase reductase Sdr
BZ166_RS05205	COG0471	metal ion transport
BZ166_RS05210	COG2318	DinB family
BZ166_RS05215	COG1388	LysM domain
BZ166_RS05225	COG1388	LysM domain
BZ166_RS05230	COG1388	LysM domain
BZ166_RS05235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BZ166_RS05245	COG1054	Belongs to the UPF0176 family
BZ166_RS05260	COG1511	domain protein
BZ166_RS05260	COG1511	domain protein
BZ166_RS05275	COG2207	Transcriptional regulator
BZ166_RS05275	COG1917	Cupin 2, conserved barrel domain protein
BZ166_RS05300	COG2022	thiamine diphosphate biosynthetic process
BZ166_RS05320	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BZ166_RS05325	COG4932	domain protein
BZ166_RS05325	COG3583	domain protein
BZ166_RS05325	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZ166_RS05330	COG0431	NADPH-dependent FMN reductase
BZ166_RS05340	COG0346	lactoylglutathione lyase activity
BZ166_RS05355	COG3583	domain protein
BZ166_RS05355	COG4932	domain protein
BZ166_RS05355	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZ166_RS05430	COG0477	Major facilitator Superfamily
BZ166_RS05440	COG2814	Major facilitator Superfamily
BZ166_RS05460	COG0584	glycerophosphoryl diester phosphodiesterase
BZ166_RS05480	COG1846	Transcriptional regulator
BZ166_RS05485	COG3961	Belongs to the TPP enzyme family
BZ166_RS05525	COG0673	inositol 2-dehydrogenase activity
BZ166_RS05535	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BZ166_RS05540	COG1691	(AIR) carboxylase
BZ166_RS05545	COG1606	tRNA processing
BZ166_RS05565	COG3835	regulator
BZ166_RS05570	COG0574	Belongs to the PEP-utilizing enzyme family
BZ166_RS05570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZ166_RS05575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BZ166_RS05600	COG1476	TRANSCRIPTIONal
BZ166_RS05605	COG2807	transmembrane transport
BZ166_RS05615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZ166_RS05620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BZ166_RS05655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ166_RS05660	COG1510	regulation of RNA biosynthetic process
BZ166_RS05665	COG1012	belongs to the aldehyde dehydrogenase family
BZ166_RS05670	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BZ166_RS05675	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BZ166_RS05675	COG0463	Glycosyl transferase, family 2
BZ166_RS05680	COG0778	Nitroreductase
BZ166_RS05690	COG1957	nucleoside hydrolase
BZ166_RS05695	COG0477	Major facilitator Superfamily
BZ166_RS05730	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BZ166_RS05740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BZ166_RS05750	COG0431	NADPH-dependent FMN reductase
BZ166_RS05760	COG1414	Transcriptional regulator
BZ166_RS05775	COG1620	l-lactate permease
BZ166_RS05805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZ166_RS05845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ166_RS05855	COG3037	sugar-specific permease SgaT UlaA
BZ166_RS05880	COG1464	Belongs to the NlpA lipoprotein family
BZ166_RS05885	COG0039	L-malate dehydrogenase activity
BZ166_RS05890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ166_RS05890	COG3711	transcriptional antiterminator
BZ166_RS05895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ166_RS05895	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ166_RS05895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ166_RS05900	COG1482	cell wall glycoprotein biosynthetic process
BZ166_RS05930	COG1309	transcriptional regulator
BZ166_RS05945	COG1309	transcriptional regulator
BZ166_RS05955	COG3949	Membrane
BZ166_RS05965	COG0829	nickel cation binding
BZ166_RS05970	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BZ166_RS05975	COG0830	nickel cation binding
BZ166_RS05980	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BZ166_RS05985	COG0804	urea catabolic process
BZ166_RS05990	COG0832	Belongs to the urease beta subunit family
BZ166_RS05995	COG0831	urea catabolic process
BZ166_RS06000	COG4413	Urea transporter
BZ166_RS06045	COG0561	phosphatase activity
BZ166_RS06055	COG0167	dihydroorotate dehydrogenase activity
BZ166_RS06060	COG3001	Fructosamine kinase
BZ166_RS06070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BZ166_RS06085	COG0697	spore germination
BZ166_RS06105	COG3189	MarR family transcriptional regulator
BZ166_RS06135	COG2608	mercury ion transmembrane transporter activity
BZ166_RS06140	COG2217	Heavy metal translocating P-type atpase
BZ166_RS06150	COG1136	(ABC) transporter
BZ166_RS06205	COG1012	belongs to the aldehyde dehydrogenase family
BZ166_RS06215	COG2409	Drug exporters of the RND superfamily
BZ166_RS06230	COG1473	amidohydrolase
BZ166_RS06250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZ166_RS06260	COG3425	synthase
BZ166_RS06275	COG3386	PFAM SMP-30 Gluconolaconase
BZ166_RS06285	COG0583	DNA-binding transcription factor activity
BZ166_RS06300	COG0028	Belongs to the TPP enzyme family
BZ166_RS06310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ166_RS06320	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BZ166_RS06335	COG0657	acetylesterase activity
BZ166_RS06350	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BZ166_RS06370	COG3949	Membrane
BZ166_RS06390	COG1129	ABC transporter
BZ166_RS06410	COG1070	Carbohydrate kinase
BZ166_RS06415	COG1063	alcohol dehydrogenase
BZ166_RS06440	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BZ166_RS06455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BZ166_RS06465	COG0561	phosphatase activity
BZ166_RS06470	COG0778	Nitroreductase
BZ166_RS06475	COG2514	catechol 2,3-dioxygenase activity
BZ166_RS06485	COG1132	(ABC) transporter
BZ166_RS06500	COG1012	belongs to the aldehyde dehydrogenase family
BZ166_RS06505	COG1846	Transcriptional regulator
BZ166_RS06510	COG0346	lactoylglutathione lyase activity
BZ166_RS06515	COG0346	lactoylglutathione lyase activity
BZ166_RS06520	COG0400	carboxylic ester hydrolase activity
BZ166_RS06530	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BZ166_RS06540	COG0586	Pfam SNARE associated Golgi protein
BZ166_RS06545	COG2271	Major facilitator Superfamily
BZ166_RS06575	COG4876	unkown
BZ166_RS06580	COG2357	RelA SpoT domain protein
BZ166_RS06590	COG1802	Transcriptional regulator
BZ166_RS06595	COG1070	Carbohydrate kinase
BZ166_RS06600	COG2610	gluconate transmembrane transporter activity
BZ166_RS06605	COG3949	Membrane
BZ166_RS06620	COG3250	beta-galactosidase activity
BZ166_RS06665	COG0107	imidazoleglycerol-phosphate synthase activity
BZ166_RS06675	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BZ166_RS06680	COG0131	Imidazoleglycerol-phosphate dehydratase
BZ166_RS06685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BZ166_RS06695	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BZ166_RS06710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BZ166_RS06720	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BZ166_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
BZ166_RS06730	COG1363	Peptidase, m42
BZ166_RS06740	COG0069	glutamate synthase activity
BZ166_RS06750	COG4619	ABC transporter
BZ166_RS06755	COG0390	transport system, permease component
BZ166_RS06760	COG2814	Major facilitator Superfamily
BZ166_RS06770	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BZ166_RS06780	COG1388	LysM domain
BZ166_RS06800	COG3682	Transcriptional regulator
BZ166_RS06835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZ166_RS06835	COG1116	anion transmembrane transporter activity
BZ166_RS06845	COG1346	cytolysis
BZ166_RS06855	COG3279	Response regulator of the LytR AlgR family
BZ166_RS06870	COG4187	Peptidase family M20/M25/M40
BZ166_RS06890	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BZ166_RS06900	COG0706	membrane insertase activity
BZ166_RS06905	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BZ166_RS06920	COG2814	Major facilitator Superfamily
BZ166_RS06930	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BZ166_RS06935	COG1388	LysM domain
BZ166_RS06940	COG0588	phosphoglycerate mutase activity
BZ166_RS06965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZ166_RS06970	COG0803	Belongs to the bacterial solute-binding protein 9 family
BZ166_RS06970	COG3443	Belongs to the bacterial solute-binding protein 9 family
BZ166_RS06990	COG2116	formate transmembrane transporter activity
BZ166_RS06995	COG0454	-acetyltransferase
BZ166_RS07015	COG1846	Transcriptional regulator
BZ166_RS07050	COG1283	sodium-dependent phosphate transmembrane transporter activity
BZ166_RS07060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BZ166_RS07065	COG1288	antiporter activity
BZ166_RS07080	COG2376	Dihydroxyacetone kinase
BZ166_RS07090	COG0698	ribose 5-phosphate isomerase
BZ166_RS07125	COG0604	alcohol dehydrogenase
BZ166_RS07140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BZ166_RS07145	COG1620	l-lactate permease
BZ166_RS07165	COG0745	RESPONSE REGULATOR receiver
BZ166_RS07170	COG0577	efflux transmembrane transporter activity
BZ166_RS07175	COG1136	(ABC) transporter
BZ166_RS07190	COG4640	response to antibiotic
BZ166_RS07205	COG1566	PFAM secretion protein HlyD family protein
BZ166_RS07210	COG2814	Major facilitator Superfamily
BZ166_RS07235	COG0598	Magnesium transport protein CorA
BZ166_RS07250	COG1695	Transcriptional regulator
BZ166_RS07265	COG1757	Na H antiporter
BZ166_RS07280	COG4152	abc transporter atp-binding protein
BZ166_RS07285	COG1668	transmembrane transport
BZ166_RS07290	COG2017	converts alpha-aldose to the beta-anomer
BZ166_RS07295	COG2258	MOSC domain
BZ166_RS07300	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BZ166_RS07305	COG1266	CAAX protease self-immunity
BZ166_RS07310	COG0010	Belongs to the arginase family
BZ166_RS07320	COG3314	Sporulation integral membrane protein YlbJ
BZ166_RS07325	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BZ166_RS07330	COG1228	amidohydrolase
BZ166_RS07335	COG0659	secondary active sulfate transmembrane transporter activity
BZ166_RS07340	COG1473	amidohydrolase
BZ166_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
BZ166_RS07350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BZ166_RS07365	COG1737	Transcriptional regulator
BZ166_RS07380	COG0385	Bile acid
BZ166_RS07430	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BZ166_RS07460	COG1316	TRANSCRIPTIONal
BZ166_RS07480	COG4193	domain, Protein
BZ166_RS07490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ166_RS07495	COG2076	Multidrug Resistance protein
BZ166_RS07500	COG2076	Multidrug Resistance protein
BZ166_RS07525	COG3942	CHAP domain
BZ166_RS07565	COG1126	abc transporter atp-binding protein
BZ166_RS07570	COG1960	acyl-CoA dehydrogenase activity
BZ166_RS07575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZ166_RS07580	COG1268	BioY protein
BZ166_RS07590	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BZ166_RS07595	COG1609	Transcriptional regulator
BZ166_RS07600	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BZ166_RS07605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BZ166_RS07610	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BZ166_RS07615	COG0725	ABC transporter, periplasmic molybdate-binding protein
BZ166_RS07620	COG4149	molybdate abc transporter
BZ166_RS07635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BZ166_RS07640	COG0521	Mo-molybdopterin cofactor biosynthetic process
BZ166_RS07645	COG0315	cyclic pyranopterin monophosphate synthase activity
BZ166_RS07655	COG1763	Mo-molybdopterin cofactor biosynthetic process
BZ166_RS07670	COG0746	molybdenum cofactor guanylyltransferase activity
BZ166_RS07675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BZ166_RS07685	COG2814	Major facilitator Superfamily
BZ166_RS07705	COG2348	transferase activity, transferring amino-acyl groups
BZ166_RS07730	COG4975	Glucose uptake
BZ166_RS07755	COG0051	transcription antitermination factor activity, RNA binding
BZ166_RS07760	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BZ166_RS07765	COG0088	Forms part of the polypeptide exit tunnel
BZ166_RS07770	COG0089	rRNA binding
BZ166_RS07775	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BZ166_RS07780	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BZ166_RS07785	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BZ166_RS07790	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BZ166_RS07795	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BZ166_RS07800	COG0255	Belongs to the universal ribosomal protein uL29 family
BZ166_RS07805	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BZ166_RS07810	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BZ166_RS07815	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BZ166_RS07820	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BZ166_RS07825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BZ166_RS07830	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BZ166_RS07835	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BZ166_RS07840	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BZ166_RS07845	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BZ166_RS07850	COG1841	ribosomal large subunit assembly
BZ166_RS07860	COG0201	protein transport
BZ166_RS07865	COG0563	adenylate kinase activity
BZ166_RS07875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BZ166_RS07880	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BZ166_RS07890	COG0202	RNA polymerase activity
BZ166_RS07895	COG0203	ribosomal protein L17
BZ166_RS07900	COG1122	ATPase activity
BZ166_RS07915	COG0101	tRNA pseudouridine synthase activity
BZ166_RS07920	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BZ166_RS07940	COG2130	NADP-dependent
BZ166_RS07945	COG0604	alcohol dehydrogenase
BZ166_RS07950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ166_RS07965	COG1302	Protein conserved in bacteria
BZ166_RS07970	COG4264	IucA IucC family
BZ166_RS07980	COG4264	IucA IucC family
BZ166_RS07985	COG3457	Alanine racemase
BZ166_RS07990	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BZ166_RS07995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ166_RS08005	COG3314	Sporulation integral membrane protein YlbJ
BZ166_RS08010	COG2329	Antibiotic biosynthesis monooxygenase
BZ166_RS08025	COG4284	Utp--glucose-1-phosphate uridylyltransferase
BZ166_RS08045	COG2814	Major facilitator Superfamily
BZ166_RS08105	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BZ166_RS08120	COG0246	Mannitol dehydrogenase
BZ166_RS08135	COG2213	PTS system mannitol-specific
BZ166_RS08145	COG1119	ATPase activity
BZ166_RS08150	COG0561	phosphatase activity
BZ166_RS08175	COG0702	epimerase
BZ166_RS08215	COG0783	Belongs to the Dps family
BZ166_RS08225	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BZ166_RS08230	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BZ166_RS08235	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BZ166_RS08245	COG1854	S-ribosylhomocysteine lyase activity
BZ166_RS08275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ166_RS08280	COG3343	RNA polymerase activity
BZ166_RS08285	COG0504	CTP synthase activity
BZ166_RS08295	COG0191	fructose-bisphosphate aldolase activity
BZ166_RS08310	COG1012	belongs to the aldehyde dehydrogenase family
BZ166_RS08315	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BZ166_RS08320	COG0254	rRNA binding
BZ166_RS08345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BZ166_RS08355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BZ166_RS08360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BZ166_RS08365	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BZ166_RS08375	COG0356	it plays a direct role in the translocation of protons across the membrane
BZ166_RS08380	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BZ166_RS08385	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BZ166_RS08390	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BZ166_RS08395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BZ166_RS08400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BZ166_RS08405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BZ166_RS08410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BZ166_RS08420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BZ166_RS08425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BZ166_RS08435	COG0629	single-stranded DNA binding
BZ166_RS08440	COG1388	LysM domain
BZ166_RS08445	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BZ166_RS08455	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BZ166_RS08460	COG0352	thiamine-phosphate diphosphorylase activity
BZ166_RS08465	COG0706	membrane insertase activity
BZ166_RS08470	COG1418	mRNA catabolic process
BZ166_RS08480	COG1937	Protein conserved in bacteria
BZ166_RS08500	COG1181	Belongs to the D-alanine--D-alanine ligase family
BZ166_RS08525	COG3402	PFAM membrane-flanked domain
BZ166_RS08565	COG1191	sigma factor activity
BZ166_RS08570	COG2183	response to ionizing radiation
BZ166_RS08605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BZ166_RS08625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BZ166_RS08630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BZ166_RS08635	COG0440	acetolactate synthase activity
BZ166_RS08650	COG0802	atpase or kinase
BZ166_RS08655	COG1214	PFAM Peptidase M22, glycoprotease
BZ166_RS08660	COG0456	acetyltransferase
BZ166_RS08665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BZ166_RS08675	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BZ166_RS08680	COG0488	(ABC) transporter
BZ166_RS08690	COG2391	methyltransferase activity
BZ166_RS08695	COG0425	Belongs to the sulfur carrier protein TusA family
BZ166_RS08700	COG1621	beta-fructofuranosidase activity
BZ166_RS08705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ166_RS08710	COG3279	Response regulator of the LytR AlgR family
BZ166_RS08715	COG3290	protein histidine kinase activity
BZ166_RS08725	COG4512	PFAM Accessory gene regulator B
BZ166_RS08730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ166_RS08760	COG0459	protein refolding
BZ166_RS08780	COG1725	Transcriptional regulator
BZ166_RS08795	COG1131	(ABC) transporter
BZ166_RS08840	COG1012	belongs to the aldehyde dehydrogenase family
BZ166_RS08845	COG1227	inorganic diphosphatase activity
BZ166_RS08850	COG1335	isochorismatase
BZ166_RS08865	COG0077	Prephenate dehydratase
BZ166_RS08875	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BZ166_RS08880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BZ166_RS08885	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BZ166_RS08895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BZ166_RS08900	COG4496	protein, YerC YecD
BZ166_RS08910	COG0210	DNA helicase
BZ166_RS08915	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BZ166_RS08920	COG4851	CamS sex pheromone cAM373 precursor
BZ166_RS08930	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BZ166_RS08935	COG0154	amidase activity
BZ166_RS08940	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BZ166_RS08945	COG1597	lipid kinase activity
BZ166_RS08950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BZ166_RS08960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BZ166_RS08970	COG1528	Iron-storage protein
BZ166_RS08985	COG4129	membrane
BZ166_RS08990	COG0024	Methionine aminopeptidase
BZ166_RS09005	COG4585	Histidine kinase
BZ166_RS09015	COG1295	ribonuclease BN
BZ166_RS09030	COG4840	Belongs to the UPF0435 family
BZ166_RS09035	COG2309	aminopeptidase activity
BZ166_RS09040	COG1607	acyl-coa hydrolase
BZ166_RS09045	COG0535	radical SAM domain protein
BZ166_RS09055	COG0693	protein deglycase activity
BZ166_RS09060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BZ166_RS09065	COG2137	regulation of response to DNA damage stimulus
BZ166_RS09085	COG1988	membrane-bound metal-dependent
BZ166_RS09115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BZ166_RS09120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ166_RS09125	COG0735	belongs to the Fur family
BZ166_RS09280	COG0765	amino acid transport
BZ166_RS09300	COG0363	glucosamine-6-phosphate deaminase activity
BZ166_RS09320	COG0564	pseudouridine synthase activity
BZ166_RS09325	COG2203	Gaf domain
BZ166_RS09325	COG4585	Histidine kinase
BZ166_RS09330	COG2197	response regulator
BZ166_RS09335	COG1301	dicarboxylic acid transport
BZ166_RS09355	COG0788	formyltetrahydrofolate deformylase activity
BZ166_RS09365	COG4399	Belongs to the UPF0754 family
BZ166_RS09370	COG3679	Belongs to the UPF0342 family
BZ166_RS09390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ166_RS09405	COG0537	adenosine 5'-monophosphoramidase activity
BZ166_RS09410	COG1131	(ABC) transporter
BZ166_RS09415	COG4473	ABC transporter
BZ166_RS09425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BZ166_RS09430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BZ166_RS09435	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BZ166_RS09495	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BZ166_RS09505	COG1506	peptidase
BZ166_RS09510	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BZ166_RS09515	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BZ166_RS09525	COG0656	L-ascorbic acid biosynthetic process
BZ166_RS09530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BZ166_RS09535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BZ166_RS09545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZ166_RS09570	COG5632	N-Acetylmuramoyl-L-alanine amidase
BZ166_RS09570	COG3266	domain, Protein
BZ166_RS09570	COG4193	domain, Protein
BZ166_RS09585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZ166_RS09585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZ166_RS09590	COG0307	riboflavin synthase, alpha
BZ166_RS09595	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZ166_RS09595	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZ166_RS09600	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BZ166_RS09610	COG2267	carboxylic ester hydrolase activity
BZ166_RS09625	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BZ166_RS09630	COG1242	4 iron, 4 sulfur cluster binding
BZ166_RS09635	COG2814	Major facilitator Superfamily
BZ166_RS09640	COG0495	leucyl-tRNA aminoacylation
BZ166_RS09660	COG2244	polysaccharide biosynthetic process
BZ166_RS09665	COG1187	pseudouridine synthase activity
BZ166_RS09675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BZ166_RS09685	COG0510	thiamine kinase activity
BZ166_RS09690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BZ166_RS09695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZ166_RS09700	COG5584	Small secreted protein
BZ166_RS09705	COG1363	Peptidase, m42
BZ166_RS09710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZ166_RS09720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZ166_RS09730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BZ166_RS09735	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BZ166_RS09745	COG1605	Chorismate mutase
BZ166_RS09745	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BZ166_RS09750	COG1609	Transcriptional regulator
BZ166_RS09755	COG0123	including yeast histone deacetylase and acetoin utilization protein
BZ166_RS09765	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BZ166_RS09775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BZ166_RS09785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ166_RS09790	COG0204	Acyl-transferase
BZ166_RS09795	COG1263	PTS System
BZ166_RS09795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ166_RS09815	COG1764	response to oxidative stress
BZ166_RS09830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BZ166_RS09840	COG1956	GAF domain-containing protein
BZ166_RS09845	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BZ166_RS09855	COG0301	tRNA thio-modification
BZ166_RS09870	COG1714	RDD family
BZ166_RS09875	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BZ166_RS09880	COG0827	DNA restriction-modification system
BZ166_RS09885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BZ166_RS09895	COG0589	response to stress
BZ166_RS09900	COG0686	Belongs to the AlaDH PNT family
BZ166_RS09905	COG3142	Participates in the control of copper homeostasis
BZ166_RS09910	COG0006	proline dipeptidase activity
BZ166_RS09930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BZ166_RS09940	COG0281	malic enzyme
BZ166_RS09945	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BZ166_RS09950	COG0825	malonyl-CoA metabolic process
BZ166_RS09955	COG0205	6-phosphofructokinase activity
BZ166_RS09960	COG0469	pyruvate kinase activity
BZ166_RS09970	COG0372	Belongs to the citrate synthase family
BZ166_RS09975	COG0538	isocitrate dehydrogenase activity
BZ166_RS09980	COG0745	RESPONSE REGULATOR receiver
BZ166_RS09985	COG5002	protein histidine kinase activity
BZ166_RS09990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ166_RS09990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ166_RS10000	COG0237	dephospho-CoA kinase activity
BZ166_RS10005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BZ166_RS10010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BZ166_RS10020	COG1484	DNA-dependent DNA replication
BZ166_RS10030	COG0833	amino acid
BZ166_RS10035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BZ166_RS10040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BZ166_RS10045	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BZ166_RS10050	COG4112	unkown
BZ166_RS10065	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BZ166_RS10070	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BZ166_RS10080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ166_RS10095	COG0113	porphobilinogen synthase activity
BZ166_RS10110	COG2818	Glycosylase
BZ166_RS10120	COG0285	dihydrofolate synthase activity
BZ166_RS10130	COG0656	L-ascorbic acid biosynthetic process
BZ166_RS10165	COG2249	NAD(P)H dehydrogenase (quinone) activity
BZ166_RS10200	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BZ166_RS10205	COG2868	ribosomal protein
BZ166_RS10215	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BZ166_RS10220	COG4492	Belongs to the UPF0735 family
BZ166_RS10225	COG0632	four-way junction helicase activity
BZ166_RS10230	COG2255	four-way junction helicase activity
BZ166_RS10235	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BZ166_RS10245	COG1862	Preprotein translocase
BZ166_RS10255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BZ166_RS10255	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BZ166_RS10260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BZ166_RS10270	COG1490	D-aminoacyl-tRNA deacylase activity
BZ166_RS10275	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZ166_RS10295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BZ166_RS10300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZ166_RS10305	COG1959	2 iron, 2 sulfur cluster binding
BZ166_RS10315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BZ166_RS10325	COG0488	(ABC) transporter
BZ166_RS10330	COG1104	cysteine desulfurase activity
BZ166_RS10335	COG0482	sulfurtransferase activity
BZ166_RS10345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BZ166_RS10350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BZ166_RS10355	COG4472	Bacterial protein of unknown function (DUF965)
BZ166_RS10360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BZ166_RS10365	COG3906	Belongs to the UPF0473 family
BZ166_RS10370	COG4122	O-methyltransferase activity
BZ166_RS10375	COG0826	peptidase U32
BZ166_RS10385	COG0572	uridine kinase
BZ166_RS10390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ166_RS10395	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BZ166_RS10415	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BZ166_RS10420	COG1914	H( )-stimulated, divalent metal cation uptake system
BZ166_RS10425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BZ166_RS10430	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BZ166_RS10435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BZ166_RS10440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BZ166_RS10445	COG1534	Rna-binding protein
BZ166_RS10450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BZ166_RS10455	COG1713	HD superfamily hydrolase involved in NAD metabolism
BZ166_RS10460	COG0799	negative regulation of ribosome biogenesis
BZ166_RS10480	COG0658	competence protein
BZ166_RS10480	COG2333	competence protein COMEC
BZ166_RS10485	COG1466	dna polymerase III delta subunit
BZ166_RS10490	COG0268	Binds directly to 16S ribosomal RNA
BZ166_RS10495	COG0481	GTPase activity
BZ166_RS10500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZ166_RS10505	COG1420	regulation of RNA biosynthetic process
BZ166_RS10510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BZ166_RS10515	COG0443	Heat shock 70 kDa protein
BZ166_RS10520	COG0484	heat shock protein binding
BZ166_RS10525	COG2264	protein methyltransferase activity
BZ166_RS10530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BZ166_RS10535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BZ166_RS10540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BZ166_RS10545	COG1030	water channel activity
BZ166_RS10550	COG4864	UPF0365 protein
BZ166_RS10560	COG1702	phosphate starvation-inducible protein PhoH
BZ166_RS10580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BZ166_RS10585	COG1381	Involved in DNA repair and RecF pathway recombination
BZ166_RS10590	COG0423	glycine-tRNA ligase activity
BZ166_RS10595	COG0517	IMP dehydrogenase activity
BZ166_RS10600	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BZ166_RS10610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZ166_RS10615	COG2384	SAM-dependent methyltransferase
BZ166_RS10625	COG0513	Belongs to the DEAD box helicase family
BZ166_RS10630	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BZ166_RS10635	COG1121	(ABC) transporter
BZ166_RS10640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ166_RS10650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZ166_RS10655	COG0768	penicillin binding
BZ166_RS10660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BZ166_RS10665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BZ166_RS10670	COG0457	Tetratricopeptide repeat
BZ166_RS10670	COG0705	Rhomboid family
BZ166_RS10675	COG4483	Protein conserved in bacteria
BZ166_RS10680	COG1940	carbohydrate kinase activity
BZ166_RS10685	COG0011	TIGRFAM Protein of
BZ166_RS10695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BZ166_RS10700	COG1459	type II secretion system
BZ166_RS10705	COG4537	Required for transformation and DNA binding
BZ166_RS10735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BZ166_RS10745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BZ166_RS10750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BZ166_RS10755	COG0095	Lipoate-protein ligase
BZ166_RS10775	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BZ166_RS10780	COG0511	ligase activity, forming carbon-carbon bonds
BZ166_RS10785	COG0439	Biotin carboxylase
BZ166_RS10790	COG1302	Protein conserved in bacteria
BZ166_RS10795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BZ166_RS10800	COG1570	exodeoxyribonuclease VII activity
BZ166_RS10805	COG1722	exodeoxyribonuclease VII activity
BZ166_RS10820	COG0497	DNA recombination
BZ166_RS10825	COG0280	phosphate acetyltransferase
BZ166_RS10855	COG4129	membrane
BZ166_RS10860	COG2195	Cleaves the N-terminal amino acid of tripeptides
BZ166_RS10870	COG0366	Alpha amylase catalytic
BZ166_RS10880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BZ166_RS10885	COG1234	tRNA 3'-trailer cleavage
BZ166_RS10890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BZ166_RS10895	COG1028	Short-chain dehydrogenase reductase Sdr
BZ166_RS10910	COG0735	belongs to the Fur family
BZ166_RS10915	COG4974	Belongs to the 'phage' integrase family
BZ166_RS10925	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BZ166_RS10930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BZ166_RS10935	COG1187	pseudouridine synthase activity
BZ166_RS10940	COG0745	RESPONSE REGULATOR receiver
BZ166_RS10955	COG1141	Ferredoxin
BZ166_RS10975	COG0492	ferredoxin-NADP+ reductase activity
BZ166_RS10985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BZ166_RS10990	COG0539	negative regulation of cytoplasmic translation
BZ166_RS10995	COG1160	GTP binding
BZ166_RS11000	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BZ166_RS11015	COG2226	methyltransferase
BZ166_RS11020	COG0142	geranyltranstransferase activity
BZ166_RS11025	COG0105	UTP biosynthetic process
BZ166_RS11035	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BZ166_RS11040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BZ166_RS11050	COG5582	Belongs to the UPF0302 family
BZ166_RS11055	COG4347	Protein of unknown function (DUF1405)
BZ166_RS11060	COG2738	Putative neutral zinc metallopeptidase
BZ166_RS11065	COG1694	Mazg nucleotide pyrophosphohydrolase
BZ166_RS11070	COG0438	transferase activity, transferring glycosyl groups
BZ166_RS11095	COG3935	DnaD domain protein
BZ166_RS11110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BZ166_RS11110	COG4499	WXG100 protein secretion system (Wss), protein YukC
BZ166_RS11125	COG4474	Belongs to the UPF0398 family
BZ166_RS11130	COG3599	regulation of cell shape
BZ166_RS11140	COG0116	Belongs to the methyltransferase superfamily
BZ166_RS11155	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BZ166_RS11160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ166_RS11165	COG0328	RNA-DNA hybrid ribonuclease activity
BZ166_RS11170	COG3545	Serine hydrolase
BZ166_RS11175	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BZ166_RS11185	COG1413	lyase activity
BZ166_RS11190	COG1413	lyase activity
BZ166_RS11200	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BZ166_RS11215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BZ166_RS11215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BZ166_RS11225	COG4479	Belongs to the UPF0346 family
BZ166_RS11230	COG0793	Belongs to the peptidase S41A family
BZ166_RS11240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BZ166_RS11250	COG0745	RESPONSE REGULATOR receiver
BZ166_RS11255	COG5002	protein histidine kinase activity
BZ166_RS11265	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZ166_RS11280	COG2207	Transcriptional regulator
BZ166_RS11280	COG1917	Cupin 2, conserved barrel domain protein
BZ166_RS11285	COG1082	Xylose isomerase domain protein TIM barrel
BZ166_RS11300	COG0673	inositol 2-dehydrogenase activity
BZ166_RS11330	COG4548	von Willebrand factor, type A
BZ166_RS11335	COG1114	Component of the transport system for branched-chain amino acids
BZ166_RS11340	COG3853	Toxic anion resistance protein (TelA)
BZ166_RS11350	COG1254	Belongs to the acylphosphatase family
BZ166_RS11360	COG1278	Cold shock
BZ166_RS11375	COG1473	amidohydrolase
BZ166_RS11385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BZ166_RS11390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BZ166_RS11395	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZ166_RS11410	COG0488	(ABC) transporter
BZ166_RS11415	COG2996	Protein conserved in bacteria
BZ166_RS11420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BZ166_RS11425	COG0573	inorganic phosphate transmembrane transporter activity
BZ166_RS11430	COG0581	inorganic phosphate transmembrane transporter activity
BZ166_RS11435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BZ166_RS11440	COG0704	Plays a role in the regulation of phosphate uptake
BZ166_RS11475	COG2348	transferase activity, transferring amino-acyl groups
BZ166_RS11485	COG0159	tryptophan synthase activity
BZ166_RS11490	COG0133	tryptophan synthase activity
BZ166_RS11500	COG0134	indole-3-glycerol-phosphate synthase activity
BZ166_RS11510	COG0512	Glutamine amidotransferase of anthranilate synthase
BZ166_RS11515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BZ166_RS11520	COG0287	Prephenate dehydrogenase
BZ166_RS11525	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BZ166_RS11535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BZ166_RS11540	COG1942	4-Oxalocrotonate Tautomerase
BZ166_RS11560	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ166_RS11565	COG1129	ABC transporter
BZ166_RS11570	COG1869	D-ribose catabolic process
BZ166_RS11595	COG1115	amino acid carrier protein
BZ166_RS11600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BZ166_RS11610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BZ166_RS11615	COG4841	protein insertion into membrane
BZ166_RS11620	COG0824	Thioesterase
BZ166_RS11625	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BZ166_RS11635	COG1970	mechanosensitive ion channel activity
BZ166_RS11640	COG0419	ATPase involved in DNA repair
BZ166_RS11645	COG0420	3'-5' exonuclease activity
BZ166_RS11650	COG4846	Membrane protein involved in cytochrome C biogenesis
BZ166_RS11660	COG3763	UPF0154 protein
BZ166_RS11680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BZ166_RS11690	COG0516	GMP reductase activity
BZ166_RS11695	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BZ166_RS11700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BZ166_RS11710	COG0753	catalase activity
BZ166_RS11715	COG0833	amino acid
BZ166_RS11725	COG0561	phosphatase activity
BZ166_RS11730	COG0083	homoserine kinase activity
BZ166_RS11735	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BZ166_RS11740	COG0460	homoserine dehydrogenase
BZ166_RS11745	COG0527	aspartate kinase activity
BZ166_RS11785	COG0174	glutamine synthetase
BZ166_RS11790	COG0789	Transcriptional regulator
BZ166_RS11800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BZ166_RS11805	COG0386	Belongs to the glutathione peroxidase family
BZ166_RS11810	COG1923	regulation of RNA biosynthetic process
BZ166_RS11815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BZ166_RS11825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZ166_RS11840	COG1619	proteins homologs of microcin C7 resistance protein MccF
BZ166_RS11850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BZ166_RS11855	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BZ166_RS11865	COG4550	Control of competence regulator ComK, YlbF/YmcA
BZ166_RS11870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BZ166_RS11885	COG1959	2 iron, 2 sulfur cluster binding
BZ166_RS11900	COG1013	pyruvate-flavodoxin oxidoreductase activity
BZ166_RS11920	COG1418	mRNA catabolic process
BZ166_RS11940	COG1426	Protein conserved in bacteria
BZ166_RS11955	COG0612	Peptidase, M16
BZ166_RS11960	COG0612	Peptidase, M16
BZ166_RS11975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BZ166_RS11980	COG1185	polyribonucleotide nucleotidyltransferase activity
BZ166_RS11985	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BZ166_RS11990	COG0196	riboflavin kinase activity
BZ166_RS11995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BZ166_RS12000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BZ166_RS12015	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BZ166_RS12020	COG1358	cellular component organization or biogenesis
BZ166_RS12025	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BZ166_RS12030	COG0195	Participates in both transcription termination and antitermination
BZ166_RS12035	COG0779	Required for maturation of 30S ribosomal subunits
BZ166_RS12060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BZ166_RS12065	COG0233	cytoplasmic translational termination
BZ166_RS12070	COG0528	UMP kinase activity
BZ166_RS12075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BZ166_RS12080	COG0052	Belongs to the universal ribosomal protein uS2 family
BZ166_RS12085	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BZ166_RS12090	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BZ166_RS12095	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BZ166_RS12100	COG4974	Belongs to the 'phage' integrase family
BZ166_RS12115	COG0758	DNA mediated transformation
BZ166_RS12130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BZ166_RS12140	COG4485	Bacterial membrane protein, YfhO
BZ166_RS12150	COG0335	large ribosomal subunit rRNA binding
BZ166_RS12155	COG0336	Belongs to the RNA methyltransferase TrmD family
BZ166_RS12160	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BZ166_RS12165	COG0228	four-way junction DNA binding
BZ166_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
BZ166_RS12175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BZ166_RS12180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BZ166_RS12185	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BZ166_RS12190	COG0552	protein localization to endoplasmic reticulum
BZ166_RS12200	COG0571	ribonuclease III activity
BZ166_RS12205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BZ166_RS12220	COG0416	fatty acid biosynthetic process
BZ166_RS12225	COG1349	DNA-binding transcription factor activity
BZ166_RS12235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BZ166_RS12240	COG1760	l-serine dehydratase
BZ166_RS12245	COG1760	l-serine dehydratase
BZ166_RS12255	COG1302	Protein conserved in bacteria
BZ166_RS12260	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BZ166_RS12265	COG1564	THIamine pyrophosphokinase
BZ166_RS12270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BZ166_RS12275	COG1162	GTPase activity
BZ166_RS12285	COG0631	protein serine/threonine phosphatase activity
BZ166_RS12295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BZ166_RS12295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BZ166_RS12300	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BZ166_RS12320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BZ166_RS12325	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BZ166_RS12330	COG1758	RNA polymerase activity
BZ166_RS12335	COG0194	GDP metabolic process
BZ166_RS12340	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BZ166_RS12355	COG2814	Major facilitator Superfamily
BZ166_RS12365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BZ166_RS12370	COG0284	orotidine-5'-phosphate decarboxylase activity
BZ166_RS12375	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BZ166_RS12390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ166_RS12465	COG1388	LysM domain
BZ166_RS12535	COG1136	(ABC) transporter
BZ166_RS12570	COG0463	Glycosyl transferase, family 2
BZ166_RS12570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC