locus-tag	class	description
MUA44_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MUA44_RS00010	COG0592	DNA-directed DNA polymerase activity
MUA44_RS00015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MUA44_RS00015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MUA44_RS00020	COG2501	S4 domain
MUA44_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MUA44_RS00030	COG0187	DNA topoisomerase II activity
MUA44_RS00040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MUA44_RS00045	COG2986	histidine ammonia-lyase
MUA44_RS00055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MUA44_RS00065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MUA44_RS00070	COG4241	membrane
MUA44_RS00075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MUA44_RS00080	COG0359	binds to the 23S rRNA
MUA44_RS00090	COG0305	Participates in initiation and elongation during chromosome replication
MUA44_RS00095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MUA44_RS00100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MUA44_RS00120	COG0745	RESPONSE REGULATOR receiver
MUA44_RS00125	COG5002	protein histidine kinase activity
MUA44_RS00130	COG4863	YycH protein
MUA44_RS00140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MUA44_RS00150	COG1196	nuclear chromosome segregation
MUA44_RS00160	COG0693	protein deglycase activity
MUA44_RS00190	COG3832	glyoxalase III activity
MUA44_RS00205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUA44_RS00250	COG0747	negative chemotaxis
MUA44_RS00260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUA44_RS00265	COG4172	Belongs to the ABC transporter superfamily
MUA44_RS00270	COG1124	(ABC) transporter
MUA44_RS00285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUA44_RS00305	COG0659	secondary active sulfate transmembrane transporter activity
MUA44_RS00320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA44_RS00325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MUA44_RS00345	COG4975	Glucose uptake
MUA44_RS00365	COG0202	RNA polymerase activity
MUA44_RS00380	COG0513	Belongs to the DEAD box helicase family
MUA44_RS00400	COG0531	amino acid
MUA44_RS00410	COG2357	RelA SpoT domain protein
MUA44_RS00415	COG2217	Heavy metal translocating P-type atpase
MUA44_RS00435	COG4409	exo-alpha-(2->6)-sialidase activity
MUA44_RS00465	COG2188	Transcriptional regulator
MUA44_RS00475	COG2723	6-phospho-beta-galactosidase activity
MUA44_RS00495	COG0454	-acetyltransferase
MUA44_RS00505	COG0201	protein transport
MUA44_RS00515	COG1073	alpha beta
MUA44_RS00525	COG0653	protein targeting
MUA44_RS00540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MUA44_RS00555	COG3655	Transcriptional regulator
MUA44_RS00560	COG3177	Filamentation induced by cAMP protein fic
MUA44_RS00565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MUA44_RS00580	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MUA44_RS00585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUA44_RS00605	COG2235	arginine
MUA44_RS00620	COG2197	response regulator
MUA44_RS00625	COG2203	Gaf domain
MUA44_RS00625	COG4585	Histidine kinase
MUA44_RS00630	COG0842	Transport permease protein
MUA44_RS00635	COG1131	(ABC) transporter
MUA44_RS00655	COG0431	NADPH-dependent FMN reductase
MUA44_RS00665	COG4932	domain protein
MUA44_RS00665	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MUA44_RS00665	COG3583	domain protein
MUA44_RS00685	COG1353	crispr-associated protein
MUA44_RS00690	COG1421	Csm2 Type III-A
MUA44_RS00695	COG1337	RAMP superfamily
MUA44_RS00700	COG1567	CRISPR-associated RAMP protein, Csm4 family
MUA44_RS00705	COG1332	CRISPR-associated RAMP protein, Csm5 family
MUA44_RS00720	COG2226	methyltransferase
MUA44_RS00730	COG2508	Transcriptional regulator
MUA44_RS00735	COG1953	Uracil, thiamine, allantoin
MUA44_RS00740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUA44_RS00745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA44_RS00755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA44_RS00760	COG3257	ureidoglycine aminohydrolase activity
MUA44_RS00765	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MUA44_RS00770	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MUA44_RS00775	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MUA44_RS00780	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MUA44_RS00795	COG2807	transmembrane transport
MUA44_RS00825	COG0657	acetylesterase activity
MUA44_RS00845	COG1609	Transcriptional regulator
MUA44_RS00855	COG0673	inositol 2-dehydrogenase activity
MUA44_RS00865	COG0366	Alpha amylase catalytic
MUA44_RS00875	COG3833	ABC-type maltose transport systems, permease component
MUA44_RS00880	COG1175	transmembrane transport
MUA44_RS00890	COG3842	ATPase activity
MUA44_RS00895	COG0475	glutathione-regulated potassium exporter activity
MUA44_RS00900	COG0490	domain, Protein
MUA44_RS00910	COG0346	lactoylglutathione lyase activity
MUA44_RS00920	COG0366	Alpha amylase catalytic
MUA44_RS00925	COG2188	Transcriptional regulator
MUA44_RS00930	COG2222	sugar isomerase
MUA44_RS00935	COG1105	Belongs to the carbohydrate kinase PfkB family
MUA44_RS00940	COG3684	Belongs to the aldolase LacD family
MUA44_RS00950	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA44_RS00950	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA44_RS00955	COG3715	PTS system
MUA44_RS00960	COG3716	PTS system mannose fructose sorbose family IID component
MUA44_RS00970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MUA44_RS01000	COG3314	Sporulation integral membrane protein YlbJ
MUA44_RS01020	COG1063	alcohol dehydrogenase
MUA44_RS01030	COG1620	l-lactate permease
MUA44_RS01035	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MUA44_RS01040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MUA44_RS01045	COG0156	8-amino-7-oxononanoate synthase activity
MUA44_RS01090	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MUA44_RS01100	COG2910	NAD(P)H-binding
MUA44_RS01105	COG2814	Major facilitator Superfamily
MUA44_RS01110	COG1335	isochorismatase
MUA44_RS01115	COG1309	transcriptional regulator
MUA44_RS01125	COG0076	glutamate decarboxylase activity
MUA44_RS01130	COG0076	glutamate decarboxylase activity
MUA44_RS01145	COG2318	DinB family
MUA44_RS01150	COG0753	catalase activity
MUA44_RS01160	COG0783	Belongs to the Dps family
MUA44_RS01170	COG0436	Aminotransferase
MUA44_RS01195	COG1136	(ABC) transporter
MUA44_RS01205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUA44_RS01220	COG2814	Major facilitator Superfamily
MUA44_RS01235	COG0431	NADPH-dependent FMN reductase
MUA44_RS01250	COG1755	Isoprenylcysteine carboxyl methyltransferase
MUA44_RS01275	COG0579	oxidoreductase
MUA44_RS01295	COG1073	alpha beta
MUA44_RS01315	COG0438	transferase activity, transferring glycosyl groups
MUA44_RS01330	COG0183	Belongs to the thiolase family
MUA44_RS01345	COG0318	PFAM AMP-dependent synthetase and ligase
MUA44_RS01355	COG2814	Major facilitator Superfamily
MUA44_RS01360	COG1960	acyl-CoA dehydrogenase activity
MUA44_RS01365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MUA44_RS01395	COG1609	Transcriptional regulator
MUA44_RS01400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUA44_RS01405	COG1869	D-ribose catabolic process
MUA44_RS01410	COG1129	ABC transporter
MUA44_RS01415	COG1172	Belongs to the binding-protein-dependent transport system permease family
MUA44_RS01420	COG1879	ABC-type sugar transport system periplasmic component
MUA44_RS01430	COG2409	Drug exporters of the RND superfamily
MUA44_RS01465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA44_RS01465	COG3711	transcriptional antiterminator
MUA44_RS01470	COG2213	PTS system mannitol-specific
MUA44_RS01470	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA44_RS01475	COG3414	Phosphotransferase system galactitol-specific IIB component
MUA44_RS01480	COG3775	system Galactitol-specific IIC component
MUA44_RS01485	COG1063	alcohol dehydrogenase
MUA44_RS01495	COG1063	alcohol dehydrogenase
MUA44_RS01500	COG3711	transcriptional antiterminator
MUA44_RS01505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA44_RS01515	COG3037	sugar-specific permease SgaT UlaA
MUA44_RS01525	COG1328	CTP reductase activity
MUA44_RS01535	COG3443	Belongs to the bacterial solute-binding protein 9 family
MUA44_RS01535	COG0803	Belongs to the bacterial solute-binding protein 9 family
MUA44_RS01570	COG2972	Histidine kinase
MUA44_RS01585	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA44_RS01590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MUA44_RS01595	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MUA44_RS01600	COG0477	Major facilitator Superfamily
MUA44_RS01605	COG2211	Major facilitator Superfamily
MUA44_RS01610	COG3250	beta-galactosidase activity
MUA44_RS01615	COG1957	nucleoside hydrolase
MUA44_RS01630	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MUA44_RS01635	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
MUA44_RS01640	COG2807	transmembrane transport
MUA44_RS01645	COG1396	sequence-specific DNA binding
MUA44_RS01665	COG1785	Belongs to the alkaline phosphatase family
MUA44_RS01670	COG0494	nUDIX hydrolase
MUA44_RS01675	COG0556	nucleotide-excision repair
MUA44_RS01690	COG1510	regulation of RNA biosynthetic process
MUA44_RS01695	COG1012	belongs to the aldehyde dehydrogenase family
MUA44_RS01700	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MUA44_RS01710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUA44_RS01720	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MUA44_RS01735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUA44_RS01740	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MUA44_RS01745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MUA44_RS01750	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MUA44_RS01770	COG1511	domain protein
MUA44_RS01795	COG2376	Dihydroxyacetone kinase
MUA44_RS01800	COG1461	Dihydroxyacetone kinase
MUA44_RS01805	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
MUA44_RS01810	COG2824	Alkylphosphonate utilization operon protein PhnA
MUA44_RS01815	COG1012	belongs to the aldehyde dehydrogenase family
MUA44_RS01840	COG0596	Alpha beta hydrolase
MUA44_RS01845	COG0789	Transcriptional regulator
MUA44_RS01850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA44_RS01850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA44_RS01850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA44_RS01860	COG3942	CHAP domain
MUA44_RS01860	COG1705	Flagellar rod assembly protein muramidase FlgJ
MUA44_RS01870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MUA44_RS01875	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MUA44_RS01880	COG0747	negative chemotaxis
MUA44_RS01905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA44_RS01905	COG0463	Glycosyl transferase, family 2
MUA44_RS01910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA44_RS01910	COG0463	Glycosyl transferase, family 2
MUA44_RS01915	COG0438	transferase activity, transferring glycosyl groups
MUA44_RS01920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUA44_RS01925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA44_RS01940	COG3181	Tripartite tricarboxylate transporter family receptor
MUA44_RS01945	COG0778	Nitroreductase
MUA44_RS01950	COG3001	Fructosamine kinase
MUA44_RS01975	COG1136	(ABC) transporter
MUA44_RS01980	COG0577	efflux transmembrane transporter activity
MUA44_RS02000	COG4413	Urea transporter
MUA44_RS02010	COG0832	Belongs to the urease beta subunit family
MUA44_RS02015	COG0804	urea catabolic process
MUA44_RS02020	COG0717	Belongs to the dCTP deaminase family
MUA44_RS02025	COG0523	cobalamin synthesis protein
MUA44_RS02050	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUA44_RS02060	COG0583	DNA-binding transcription factor activity
MUA44_RS02070	COG1346	cytolysis
MUA44_RS02090	COG1846	Transcriptional regulator
MUA44_RS02095	COG0778	Nitroreductase
MUA44_RS02100	COG2357	RelA SpoT domain protein
MUA44_RS02135	COG1349	DNA-binding transcription factor activity
MUA44_RS02140	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
MUA44_RS02145	COG1070	Carbohydrate kinase
MUA44_RS02150	COG0235	Class ii aldolase
MUA44_RS02165	COG1012	belongs to the aldehyde dehydrogenase family
MUA44_RS02175	COG1028	Short-chain dehydrogenase reductase Sdr
MUA44_RS02190	COG3835	regulator
MUA44_RS02205	COG3961	Belongs to the TPP enzyme family
MUA44_RS02210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MUA44_RS02215	COG0512	Glutamine amidotransferase of anthranilate synthase
MUA44_RS02225	COG0134	indole-3-glycerol-phosphate synthase activity
MUA44_RS02230	COG0135	phosphoribosylanthranilate isomerase activity
MUA44_RS02235	COG0133	tryptophan synthase activity
MUA44_RS02240	COG0159	tryptophan synthase activity
MUA44_RS02260	COG0277	FAD linked oxidase domain protein
MUA44_RS02265	COG0247	lactate metabolic process
MUA44_RS02270	COG1132	(ABC) transporter
MUA44_RS02275	COG1132	(ABC) transporter
MUA44_RS02280	COG0789	Transcriptional regulator
MUA44_RS02285	COG0346	lactoylglutathione lyase activity
MUA44_RS02290	COG3871	stress protein (general stress protein 26)
MUA44_RS02295	COG1115	amino acid carrier protein
MUA44_RS02300	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
MUA44_RS02305	COG2814	Major facilitator Superfamily
MUA44_RS02310	COG2271	Major facilitator Superfamily
MUA44_RS02315	COG3764	Sortase (surface protein transpeptidase)
MUA44_RS02320	COG1929	Belongs to the glycerate kinase type-1 family
MUA44_RS02330	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MUA44_RS02350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MUA44_RS02355	COG0702	epimerase
MUA44_RS02370	COG0444	Belongs to the ABC transporter superfamily
MUA44_RS02375	COG4608	Belongs to the ABC transporter superfamily
MUA44_RS02380	COG0601	transmembrane transport
MUA44_RS02385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUA44_RS02400	COG1760	l-serine dehydratase
MUA44_RS02405	COG1760	l-serine dehydratase
MUA44_RS02435	COG0471	metal ion transport
MUA44_RS02440	COG2116	formate transmembrane transporter activity
MUA44_RS02445	COG0454	-acetyltransferase
MUA44_RS02455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MUA44_RS02455	COG1648	precorrin-2 dehydrogenase activity
MUA44_RS02460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUA44_RS02465	COG2146	nitrite reductase [NAD(P)H] activity
MUA44_RS02470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MUA44_RS02470	COG1648	precorrin-2 dehydrogenase activity
MUA44_RS02475	COG0737	Belongs to the 5'-nucleotidase family
MUA44_RS02480	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MUA44_RS02485	COG1140	nitrate reductase beta subunit
MUA44_RS02495	COG2181	nitrate reductase activity
MUA44_RS02505	COG4585	Histidine kinase
MUA44_RS02510	COG2197	response regulator
MUA44_RS02515	COG2223	nitrite transmembrane transporter activity
MUA44_RS02520	COG4187	Peptidase family M20/M25/M40
MUA44_RS02530	COG0039	L-malate dehydrogenase activity
MUA44_RS02535	COG1363	Peptidase, m42
MUA44_RS02540	COG0697	spore germination
MUA44_RS02550	COG2807	transmembrane transport
MUA44_RS02560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA44_RS02560	COG1263	PTS System
MUA44_RS02575	COG1283	sodium-dependent phosphate transmembrane transporter activity
MUA44_RS02605	COG2814	Major facilitator Superfamily
MUA44_RS02610	COG0604	alcohol dehydrogenase
MUA44_RS02625	COG1620	l-lactate permease
MUA44_RS02630	COG0438	transferase activity, transferring glycosyl groups
MUA44_RS02635	COG0579	oxidoreductase
MUA44_RS02650	COG0577	efflux transmembrane transporter activity
MUA44_RS02660	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MUA44_RS02675	COG4640	response to antibiotic
MUA44_RS02685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MUA44_RS02695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA44_RS02720	COG1304	FMN binding
MUA44_RS02725	COG0523	cobalamin synthesis protein
MUA44_RS02730	COG0786	glutamate:sodium symporter activity
MUA44_RS02735	COG2207	Transcriptional regulator
MUA44_RS02760	COG1757	Na H antiporter
MUA44_RS02765	COG2094	Belongs to the DNA glycosylase MPG family
MUA44_RS02770	COG3152	Membrane
MUA44_RS02775	COG1288	antiporter activity
MUA44_RS02780	COG4152	abc transporter atp-binding protein
MUA44_RS02785	COG1668	transmembrane transport
MUA44_RS02790	COG1742	UPF0060 membrane protein
MUA44_RS02795	COG2017	converts alpha-aldose to the beta-anomer
MUA44_RS02800	COG2258	MOSC domain
MUA44_RS02805	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MUA44_RS02815	COG1266	CAAX protease self-immunity
MUA44_RS02820	COG0583	DNA-binding transcription factor activity
MUA44_RS02825	COG3314	Sporulation integral membrane protein YlbJ
MUA44_RS02830	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MUA44_RS02835	COG1228	amidohydrolase
MUA44_RS02840	COG0659	secondary active sulfate transmembrane transporter activity
MUA44_RS02845	COG1473	amidohydrolase
MUA44_RS02865	COG0385	Bile acid
MUA44_RS02875	COG0346	lactoylglutathione lyase activity
MUA44_RS02880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUA44_RS02905	COG1113	amino acid transport
MUA44_RS02930	COG1316	TRANSCRIPTIONal
MUA44_RS02945	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MUA44_RS02950	COG3383	formate dehydrogenase (NAD+) activity
MUA44_RS02975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA44_RS02980	COG2076	Multidrug Resistance protein
MUA44_RS02985	COG2076	Multidrug Resistance protein
MUA44_RS02990	COG3942	CHAP domain
MUA44_RS03000	COG1757	Na H antiporter
MUA44_RS03010	COG3942	CHAP domain
MUA44_RS03030	COG1960	acyl-CoA dehydrogenase activity
MUA44_RS03035	COG2832	Protein of unknown function (DUF454)
MUA44_RS03040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MUA44_RS03045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUA44_RS03055	COG2186	Transcriptional regulator
MUA44_RS03065	COG1268	BioY protein
MUA44_RS03080	COG1609	Transcriptional regulator
MUA44_RS03085	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MUA44_RS03090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MUA44_RS03095	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MUA44_RS03100	COG0725	ABC transporter, periplasmic molybdate-binding protein
MUA44_RS03105	COG4149	molybdate abc transporter
MUA44_RS03110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MUA44_RS03115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MUA44_RS03130	COG0303	'Molybdopterin
MUA44_RS03140	COG0314	molybdopterin synthase activity
MUA44_RS03150	COG0746	molybdenum cofactor guanylyltransferase activity
MUA44_RS03155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MUA44_RS03180	COG2348	transferase activity, transferring amino-acyl groups
MUA44_RS03185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUA44_RS03190	COG0436	Aminotransferase
MUA44_RS03215	COG0551	DNA topoisomerase type I activity
MUA44_RS03215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUA44_RS03220	COG2252	PERMEase
MUA44_RS03235	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MUA44_RS03240	COG0088	Forms part of the polypeptide exit tunnel
MUA44_RS03245	COG0089	rRNA binding
MUA44_RS03250	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MUA44_RS03255	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MUA44_RS03260	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MUA44_RS03265	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MUA44_RS03270	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MUA44_RS03275	COG0255	Belongs to the universal ribosomal protein uL29 family
MUA44_RS03285	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MUA44_RS03300	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MUA44_RS03305	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MUA44_RS03310	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MUA44_RS03320	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MUA44_RS03325	COG1841	ribosomal large subunit assembly
MUA44_RS03335	COG0201	protein transport
MUA44_RS03350	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MUA44_RS03360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MUA44_RS03365	COG0202	RNA polymerase activity
MUA44_RS03370	COG0203	ribosomal protein L17
MUA44_RS03375	COG1122	ATPase activity
MUA44_RS03380	COG1122	ATPase activity
MUA44_RS03390	COG0101	tRNA pseudouridine synthase activity
MUA44_RS03395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MUA44_RS03400	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MUA44_RS03410	COG1335	isochorismatase
MUA44_RS03425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUA44_RS03440	COG1302	Protein conserved in bacteria
MUA44_RS03445	COG2814	Major facilitator Superfamily
MUA44_RS03450	COG4264	IucA IucC family
MUA44_RS03455	COG2814	Major facilitator Superfamily
MUA44_RS03460	COG4264	IucA IucC family
MUA44_RS03465	COG3457	Alanine racemase
MUA44_RS03470	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MUA44_RS03475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA44_RS03480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA44_RS03485	COG3314	Sporulation integral membrane protein YlbJ
MUA44_RS03495	COG1988	membrane-bound metal-dependent
MUA44_RS03500	COG4284	Utp--glucose-1-phosphate uridylyltransferase
MUA44_RS03505	COG1272	protein, Hemolysin III
MUA44_RS03525	COG2814	Major facilitator Superfamily
MUA44_RS03530	COG0489	protein tyrosine kinase activity
MUA44_RS03595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUA44_RS03600	COG0246	Mannitol dehydrogenase
MUA44_RS03610	COG3711	transcriptional antiterminator
MUA44_RS03630	COG1119	ATPase activity
MUA44_RS03635	COG0561	phosphatase activity
MUA44_RS03645	COG2186	Transcriptional regulator
MUA44_RS03650	COG1482	cell wall glycoprotein biosynthetic process
MUA44_RS03665	COG1757	Na H antiporter
MUA44_RS03675	COG0813	purine-nucleoside phosphorylase activity
MUA44_RS03680	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MUA44_RS03710	COG5146	pantothenate kinase activity
MUA44_RS03725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUA44_RS03735	COG0504	CTP synthase activity
MUA44_RS03740	COG2271	Major facilitator Superfamily
MUA44_RS03745	COG4821	SIS domain
MUA44_RS03750	COG0191	fructose-bisphosphate aldolase activity
MUA44_RS03755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUA44_RS03760	COG1733	regulation of RNA biosynthetic process
MUA44_RS03770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MUA44_RS03775	COG0254	rRNA binding
MUA44_RS03785	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MUA44_RS03790	COG2890	protein-(glutamine-N5) methyltransferase activity
MUA44_RS03795	COG0009	L-threonylcarbamoyladenylate synthase
MUA44_RS03800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA44_RS03805	COG4475	Protein of unknown function (DUF436)
MUA44_RS03810	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MUA44_RS03815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MUA44_RS03820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MUA44_RS03830	COG0356	it plays a direct role in the translocation of protons across the membrane
MUA44_RS03835	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUA44_RS03845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUA44_RS03855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MUA44_RS03860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MUA44_RS03885	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MUA44_RS03900	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MUA44_RS03915	COG0352	thiamine-phosphate diphosphorylase activity
MUA44_RS03920	COG0706	membrane insertase activity
MUA44_RS03925	COG1418	mRNA catabolic process
MUA44_RS03930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUA44_RS03935	COG1937	Protein conserved in bacteria
MUA44_RS03950	COG2217	Heavy metal translocating P-type atpase
MUA44_RS03965	COG0772	Belongs to the SEDS family
MUA44_RS03970	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUA44_RS03975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MUA44_RS03980	COG0513	Belongs to the DEAD box helicase family
MUA44_RS03995	COG3402	PFAM membrane-flanked domain
MUA44_RS04000	COG0736	holo-[acyl-carrier-protein] synthase activity
MUA44_RS04005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MUA44_RS04015	COG2337	Toxic component of a toxin-antitoxin (TA) module
MUA44_RS04020	COG2208	phosphoserine phosphatase activity
MUA44_RS04025	COG1366	Belongs to the anti-sigma-factor antagonist family
MUA44_RS04035	COG1191	sigma factor activity
MUA44_RS04040	COG2183	response to ionizing radiation
MUA44_RS04045	COG3091	SprT-like family
MUA44_RS04085	COG0066	3-isopropylmalate dehydratase activity
MUA44_RS04090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MUA44_RS04095	COG0473	3-isopropylmalate dehydrogenase activity
MUA44_RS04100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUA44_RS04105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MUA44_RS04115	COG0028	Belongs to the TPP enzyme family
MUA44_RS04120	COG0129	dihydroxy-acid dehydratase activity
MUA44_RS04125	COG0802	atpase or kinase
MUA44_RS04130	COG1214	PFAM Peptidase M22, glycoprotease
MUA44_RS04135	COG0456	acetyltransferase
MUA44_RS04140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MUA44_RS04145	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MUA44_RS04150	COG0488	(ABC) transporter
MUA44_RS04155	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MUA44_RS04160	COG0425	Belongs to the sulfur carrier protein TusA family
MUA44_RS04165	COG2391	methyltransferase activity
MUA44_RS04170	COG1609	Transcriptional regulator
MUA44_RS04175	COG1621	beta-fructofuranosidase activity
MUA44_RS04200	COG4512	PFAM Accessory gene regulator B
MUA44_RS04235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA44_RS04240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MUA44_RS04265	COG1131	(ABC) transporter
MUA44_RS04285	COG2610	gluconate transmembrane transporter activity
MUA44_RS04320	COG2706	6-phosphogluconolactonase activity
MUA44_RS04325	COG1012	belongs to the aldehyde dehydrogenase family
MUA44_RS04335	COG1227	inorganic diphosphatase activity
MUA44_RS04340	COG1335	isochorismatase
MUA44_RS04350	COG0077	Prephenate dehydratase
MUA44_RS04360	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MUA44_RS04370	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MUA44_RS04380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MUA44_RS04385	COG4496	protein, YerC YecD
MUA44_RS04390	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MUA44_RS04395	COG0210	DNA helicase
MUA44_RS04400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MUA44_RS04405	COG4851	CamS sex pheromone cAM373 precursor
MUA44_RS04410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUA44_RS04415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUA44_RS04425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUA44_RS04430	COG1597	lipid kinase activity
MUA44_RS04435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MUA44_RS04445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUA44_RS04455	COG1528	Iron-storage protein
MUA44_RS04470	COG4129	membrane
MUA44_RS04475	COG0024	Methionine aminopeptidase
MUA44_RS04500	COG0288	reversible hydration of carbon dioxide
MUA44_RS04505	COG1295	ribonuclease BN
MUA44_RS04520	COG4840	Belongs to the UPF0435 family
MUA44_RS04525	COG2309	aminopeptidase activity
MUA44_RS04530	COG1607	acyl-coa hydrolase
MUA44_RS04540	COG0535	radical SAM domain protein
MUA44_RS04550	COG0693	protein deglycase activity
MUA44_RS04555	COG0028	Belongs to the TPP enzyme family
MUA44_RS04560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUA44_RS04575	COG1134	teichoic acid transport
MUA44_RS04575	COG1388	LysM domain
MUA44_RS04585	COG1988	membrane-bound metal-dependent
MUA44_RS04590	COG1194	a g-specific adenine glycosylase
MUA44_RS04595	COG3557	Belongs to the UPF0374 family
MUA44_RS04605	COG0069	glutamate synthase activity
MUA44_RS04610	COG4129	membrane
MUA44_RS04615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUA44_RS04620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MUA44_RS04625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA44_RS04630	COG0735	belongs to the Fur family
MUA44_RS04790	COG0765	amino acid transport
MUA44_RS04795	COG1126	abc transporter atp-binding protein
MUA44_RS04800	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MUA44_RS04805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MUA44_RS04810	COG0363	glucosamine-6-phosphate deaminase activity
MUA44_RS04825	COG0114	fumarate hydratase activity
MUA44_RS04830	COG0248	Ppx GppA phosphatase
MUA44_RS04835	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MUA44_RS04840	COG0564	pseudouridine synthase activity
MUA44_RS04845	COG4585	Histidine kinase
MUA44_RS04845	COG2203	Gaf domain
MUA44_RS04850	COG2197	response regulator
MUA44_RS04860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MUA44_RS04875	COG4399	Belongs to the UPF0754 family
MUA44_RS04880	COG3679	Belongs to the UPF0342 family
MUA44_RS04885	COG0420	3'-5' exonuclease activity
MUA44_RS04895	COG3481	metal-dependent phosphohydrolase, HD sub domain
MUA44_RS04900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MUA44_RS04905	COG2814	Major facilitator Superfamily
MUA44_RS04915	COG1846	Transcriptional regulator
MUA44_RS04925	COG0537	adenosine 5'-monophosphoramidase activity
MUA44_RS04930	COG1131	(ABC) transporter
MUA44_RS04935	COG4473	ABC transporter
MUA44_RS04945	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MUA44_RS04955	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MUA44_RS04960	COG3545	Serine hydrolase
MUA44_RS05010	COG0582	viral genome integration into host DNA
MUA44_RS05025	COG1396	sequence-specific DNA binding
MUA44_RS05035	COG3561	AntA/AntB antirepressor
MUA44_RS05125	COG0305	Participates in initiation and elongation during chromosome replication
MUA44_RS05155	COG0756	dUTP diphosphatase activity
MUA44_RS05260	COG0739	heme binding
MUA44_RS05295	COG1388	LysM domain
MUA44_RS05295	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUA44_RS05325	COG0588	phosphoglycerate mutase activity
MUA44_RS05335	COG3037	sugar-specific permease SgaT UlaA
MUA44_RS05355	COG3623	hexulose-6-phosphate isomerase
MUA44_RS05360	COG0235	Class ii aldolase
MUA44_RS05380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MUA44_RS05385	COG0494	nUDIX hydrolase
MUA44_RS05390	COG1506	peptidase
MUA44_RS05400	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MUA44_RS05405	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MUA44_RS05415	COG0656	L-ascorbic acid biosynthetic process
MUA44_RS05435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MUA44_RS05460	COG3266	domain, Protein
MUA44_RS05460	COG4193	domain, Protein
MUA44_RS05460	COG5632	N-Acetylmuramoyl-L-alanine amidase
MUA44_RS05470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUA44_RS05470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUA44_RS05475	COG0307	riboflavin synthase, alpha
MUA44_RS05480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUA44_RS05480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUA44_RS05485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MUA44_RS05500	COG2267	carboxylic ester hydrolase activity
MUA44_RS05505	COG0039	L-malate dehydrogenase activity
MUA44_RS05515	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MUA44_RS05520	COG1242	4 iron, 4 sulfur cluster binding
MUA44_RS05525	COG2814	Major facilitator Superfamily
MUA44_RS05530	COG0495	leucyl-tRNA aminoacylation
MUA44_RS05535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUA44_RS05540	COG2081	HI0933 family
MUA44_RS05545	COG2244	polysaccharide biosynthetic process
MUA44_RS05550	COG1187	pseudouridine synthase activity
MUA44_RS05560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA44_RS05565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUA44_RS05570	COG0510	thiamine kinase activity
MUA44_RS05575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MUA44_RS05580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUA44_RS05590	COG1363	Peptidase, m42
MUA44_RS05595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA44_RS05600	COG4848	Belongs to the UPF0354 family
MUA44_RS05605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUA44_RS05610	COG1674	ftsk spoiiie
MUA44_RS05615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MUA44_RS05620	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MUA44_RS05630	COG1605	Chorismate mutase
MUA44_RS05630	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MUA44_RS05635	COG1609	Transcriptional regulator
MUA44_RS05640	COG0123	including yeast histone deacetylase and acetoin utilization protein
MUA44_RS05645	COG0454	-acetyltransferase
MUA44_RS05650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUA44_RS05655	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MUA44_RS05660	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MUA44_RS05670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUA44_RS05675	COG0204	Acyl-transferase
MUA44_RS05685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MUA44_RS05690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MUA44_RS05695	COG1764	response to oxidative stress
MUA44_RS05755	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MUA44_RS05760	COG1956	GAF domain-containing protein
MUA44_RS05765	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MUA44_RS05770	COG1104	cysteine desulfurase activity
MUA44_RS05775	COG0301	tRNA thio-modification
MUA44_RS05785	COG0616	signal peptide processing
MUA44_RS05790	COG1714	RDD family
MUA44_RS05795	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MUA44_RS05800	COG0827	DNA restriction-modification system
MUA44_RS05805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MUA44_RS05810	COG0589	response to stress
MUA44_RS05815	COG0686	Belongs to the AlaDH PNT family
MUA44_RS05820	COG3142	Participates in the control of copper homeostasis
MUA44_RS05830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MUA44_RS05840	COG4109	DRTGG domain
MUA44_RS05845	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MUA44_RS05850	COG0587	DNA-directed DNA polymerase activity
MUA44_RS05855	COG0281	malic enzyme
MUA44_RS05860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MUA44_RS05865	COG0825	malonyl-CoA metabolic process
MUA44_RS05870	COG0205	6-phosphofructokinase activity
MUA44_RS05875	COG0469	pyruvate kinase activity
MUA44_RS05880	COG0372	Belongs to the citrate synthase family
MUA44_RS05885	COG0538	isocitrate dehydrogenase activity
MUA44_RS05890	COG0745	RESPONSE REGULATOR receiver
MUA44_RS05895	COG5002	protein histidine kinase activity
MUA44_RS05900	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA44_RS05900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA44_RS05910	COG0237	dephospho-CoA kinase activity
MUA44_RS05915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MUA44_RS05925	COG3611	Membrane attachment protein
MUA44_RS05930	COG1484	DNA-dependent DNA replication
MUA44_RS05940	COG0833	amino acid
MUA44_RS05950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MUA44_RS05955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MUA44_RS05975	COG0544	peptidyl-prolyl cis-trans isomerase activity
MUA44_RS05985	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MUA44_RS05990	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MUA44_RS06000	COG0181	hydroxymethylbilane synthase activity
MUA44_RS06015	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUA44_RS06025	COG2818	Glycosylase
MUA44_RS06030	COG0525	valine-tRNA ligase activity
MUA44_RS06035	COG0285	dihydrofolate synthase activity
MUA44_RS06050	COG2003	Belongs to the UPF0758 family
MUA44_RS06085	COG2868	ribosomal protein
MUA44_RS06095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MUA44_RS06105	COG0632	four-way junction helicase activity
MUA44_RS06115	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MUA44_RS06125	COG1862	Preprotein translocase
MUA44_RS06130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUA44_RS06130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUA44_RS06135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MUA44_RS06135	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MUA44_RS06140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA44_RS06150	COG1490	D-aminoacyl-tRNA deacylase activity
MUA44_RS06155	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUA44_RS06165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MUA44_RS06175	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MUA44_RS06180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MUA44_RS06185	COG1959	2 iron, 2 sulfur cluster binding
MUA44_RS06195	COG3237	CsbD-like
MUA44_RS06205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUA44_RS06210	COG1104	cysteine desulfurase activity
MUA44_RS06215	COG0482	sulfurtransferase activity
MUA44_RS06225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MUA44_RS06230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MUA44_RS06235	COG4472	Bacterial protein of unknown function (DUF965)
MUA44_RS06240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MUA44_RS06245	COG3906	Belongs to the UPF0473 family
MUA44_RS06250	COG4122	O-methyltransferase activity
MUA44_RS06255	COG0826	peptidase U32
MUA44_RS06260	COG0826	peptidase U32
MUA44_RS06265	COG0572	uridine kinase
MUA44_RS06275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MUA44_RS06280	COG1984	allophanate hydrolase subunit 2
MUA44_RS06285	COG0511	ligase activity, forming carbon-carbon bonds
MUA44_RS06290	COG0439	Biotin carboxylase
MUA44_RS06295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MUA44_RS06300	COG1914	H( )-stimulated, divalent metal cation uptake system
MUA44_RS06305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MUA44_RS06310	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MUA44_RS06315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MUA44_RS06320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUA44_RS06325	COG1534	Rna-binding protein
MUA44_RS06335	COG1713	HD superfamily hydrolase involved in NAD metabolism
MUA44_RS06340	COG0799	negative regulation of ribosome biogenesis
MUA44_RS06345	COG2226	methyltransferase
MUA44_RS06350	COG1596	polysaccharide export
MUA44_RS06350	COG1555	photosystem II stabilization
MUA44_RS06355	COG2131	deaminase
MUA44_RS06360	COG2333	competence protein COMEC
MUA44_RS06360	COG0658	competence protein
MUA44_RS06365	COG1466	dna polymerase III delta subunit
MUA44_RS06370	COG0268	Binds directly to 16S ribosomal RNA
MUA44_RS06380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MUA44_RS06400	COG0484	heat shock protein binding
MUA44_RS06405	COG2264	protein methyltransferase activity
MUA44_RS06410	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MUA44_RS06415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUA44_RS06425	COG1030	water channel activity
MUA44_RS06430	COG4864	UPF0365 protein
MUA44_RS06440	COG1702	phosphate starvation-inducible protein PhoH
MUA44_RS06450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MUA44_RS06455	COG0295	cytidine deaminase activity
MUA44_RS06460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MUA44_RS06465	COG1381	Involved in DNA repair and RecF pathway recombination
MUA44_RS06470	COG0423	glycine-tRNA ligase activity
MUA44_RS06475	COG0517	IMP dehydrogenase activity
MUA44_RS06480	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MUA44_RS06485	COG0358	DNA primase activity
MUA44_RS06490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MUA44_RS06495	COG2384	SAM-dependent methyltransferase
MUA44_RS06500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MUA44_RS06505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MUA44_RS06510	COG0513	Belongs to the DEAD box helicase family
MUA44_RS06515	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MUA44_RS06520	COG1121	(ABC) transporter
MUA44_RS06525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUA44_RS06530	COG0735	belongs to the Fur family
MUA44_RS06535	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MUA44_RS06545	COG0768	penicillin binding
MUA44_RS06550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MUA44_RS06555	COG0573	inorganic phosphate transmembrane transporter activity
MUA44_RS06560	COG0581	inorganic phosphate transmembrane transporter activity
MUA44_RS06565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MUA44_RS06570	COG0704	Plays a role in the regulation of phosphate uptake
MUA44_RS06580	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MUA44_RS06585	COG0705	Rhomboid family
MUA44_RS06585	COG0457	Tetratricopeptide repeat
MUA44_RS06590	COG4483	Protein conserved in bacteria
MUA44_RS06595	COG1940	carbohydrate kinase activity
MUA44_RS06600	COG0011	TIGRFAM Protein of
MUA44_RS06605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUA44_RS06610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MUA44_RS06640	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MUA44_RS06645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MUA44_RS06655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUA44_RS06660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUA44_RS06665	COG0095	Lipoate-protein ligase
MUA44_RS06680	COG0006	proline dipeptidase activity
MUA44_RS06685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MUA44_RS06690	COG0511	ligase activity, forming carbon-carbon bonds
MUA44_RS06695	COG0439	Biotin carboxylase
MUA44_RS06700	COG1302	Protein conserved in bacteria
MUA44_RS06710	COG1570	exodeoxyribonuclease VII activity
MUA44_RS06725	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MUA44_RS06730	COG1438	arginine binding
MUA44_RS06735	COG0497	DNA recombination
MUA44_RS06740	COG0280	phosphate acetyltransferase
MUA44_RS06745	COG3426	butyrate kinase activity
MUA44_RS06750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUA44_RS06755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MUA44_RS06760	COG0022	dehydrogenase e1 component
MUA44_RS06765	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUA44_RS06775	COG4129	membrane
MUA44_RS06785	COG2195	Cleaves the N-terminal amino acid of tripeptides
MUA44_RS06805	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MUA44_RS06810	COG1234	tRNA 3'-trailer cleavage
MUA44_RS06815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MUA44_RS06825	COG0667	Aldo Keto reductase
MUA44_RS06830	COG0494	nUDIX hydrolase
MUA44_RS06835	COG0735	belongs to the Fur family
MUA44_RS06850	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MUA44_RS06855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MUA44_RS06860	COG1187	pseudouridine synthase activity
MUA44_RS06865	COG0745	RESPONSE REGULATOR receiver
MUA44_RS06880	COG1141	Ferredoxin
MUA44_RS06890	COG0514	ATP-dependent DNA helicase (RecQ)
MUA44_RS06900	COG0492	ferredoxin-NADP+ reductase activity
MUA44_RS06910	COG0252	asparaginase activity
MUA44_RS06920	COG0539	negative regulation of cytoplasmic translation
MUA44_RS06925	COG1160	GTP binding
MUA44_RS06930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MUA44_RS06945	COG2226	methyltransferase
MUA44_RS06950	COG0142	geranyltranstransferase activity
MUA44_RS06955	COG0105	UTP biosynthetic process
MUA44_RS06965	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MUA44_RS06975	COG0457	Tetratricopeptide repeat
MUA44_RS06985	COG4347	Protein of unknown function (DUF1405)
MUA44_RS06995	COG1694	Mazg nucleotide pyrophosphohydrolase
MUA44_RS07000	COG0438	transferase activity, transferring glycosyl groups
MUA44_RS07005	COG0617	tRNA 3'-terminal CCA addition
MUA44_RS07020	COG0017	Asparaginyl-tRNA synthetase
MUA44_RS07025	COG3935	DnaD domain protein
MUA44_RS07030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MUA44_RS07040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUA44_RS07040	COG4499	WXG100 protein secretion system (Wss), protein YukC
MUA44_RS07055	COG4474	Belongs to the UPF0398 family
MUA44_RS07060	COG3599	regulation of cell shape
MUA44_RS07070	COG0116	Belongs to the methyltransferase superfamily
MUA44_RS07075	COG2962	Rard protein
MUA44_RS07080	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MUA44_RS07085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA44_RS07095	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MUA44_RS07105	COG1413	lyase activity
MUA44_RS07140	COG2190	(PTS) system
MUA44_RS07150	COG0793	Belongs to the peptidase S41A family
MUA44_RS07160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUA44_RS07165	COG0671	phosphoesterase, PA-phosphatase related
MUA44_RS07175	COG5002	protein histidine kinase activity
MUA44_RS07180	COG0567	Dehydrogenase, E1 component
MUA44_RS07205	COG0714	Associated with various cellular activities
MUA44_RS07210	COG4548	von Willebrand factor, type A
MUA44_RS07215	COG1114	Component of the transport system for branched-chain amino acids
MUA44_RS07220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUA44_RS07225	COG3853	Toxic anion resistance protein (TelA)
MUA44_RS07245	COG1278	Cold shock
MUA44_RS07260	COG1473	amidohydrolase
MUA44_RS07265	COG2171	N-acyltransferase activity
MUA44_RS07270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MUA44_RS07275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUA44_RS07280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MUA44_RS07285	COG0488	(ABC) transporter
MUA44_RS07290	COG2996	Protein conserved in bacteria
MUA44_RS07320	COG1363	Peptidase, m42
MUA44_RS07325	COG0287	Prephenate dehydrogenase
MUA44_RS07330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUA44_RS07360	COG0628	permease
MUA44_RS07370	COG3711	transcriptional antiterminator
MUA44_RS07375	COG1115	amino acid carrier protein
MUA44_RS07380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MUA44_RS07390	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MUA44_RS07395	COG4841	protein insertion into membrane
MUA44_RS07400	COG0824	Thioesterase
MUA44_RS07410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUA44_RS07415	COG1970	mechanosensitive ion channel activity
MUA44_RS07420	COG0419	ATPase involved in DNA repair
MUA44_RS07425	COG0420	3'-5' exonuclease activity
MUA44_RS07430	COG4846	Membrane protein involved in cytochrome C biogenesis
MUA44_RS07435	COG3763	UPF0154 protein
MUA44_RS07445	COG4224	UPF0291 protein
MUA44_RS07455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUA44_RS07465	COG0516	GMP reductase activity
MUA44_RS07470	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MUA44_RS07480	COG0833	amino acid
MUA44_RS07495	COG0083	homoserine kinase activity
MUA44_RS07500	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUA44_RS07505	COG0460	homoserine dehydrogenase
MUA44_RS07510	COG0527	aspartate kinase activity
MUA44_RS07530	COG1525	nuclease
MUA44_RS07560	COG0584	glycerophosphoryl diester phosphodiesterase
MUA44_RS07605	COG0789	Transcriptional regulator
MUA44_RS07610	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MUA44_RS07615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MUA44_RS07620	COG0386	Belongs to the glutathione peroxidase family
MUA44_RS07630	COG2267	carboxylic ester hydrolase activity
MUA44_RS07635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MUA44_RS07640	COG1923	regulation of RNA biosynthetic process
MUA44_RS07645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MUA44_RS07655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MUA44_RS07660	COG1619	proteins homologs of microcin C7 resistance protein MccF
MUA44_RS07665	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MUA44_RS07670	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MUA44_RS07690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUA44_RS07700	COG1013	pyruvate-flavodoxin oxidoreductase activity
MUA44_RS07705	COG0674	pyruvate-flavodoxin oxidoreductase activity
MUA44_RS07705	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MUA44_RS07710	COG1692	metallophosphoesterase
MUA44_RS07730	COG1418	mRNA catabolic process
MUA44_RS07735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MUA44_RS07740	COG1058	Belongs to the CinA family
MUA44_RS07740	COG1546	Belongs to the CinA family
MUA44_RS07760	COG0300	oxidoreductase activity
MUA44_RS07765	COG0612	Peptidase, M16
MUA44_RS07770	COG0612	Peptidase, M16
MUA44_RS07775	COG2188	Transcriptional regulator
MUA44_RS07790	COG1185	polyribonucleotide nucleotidyltransferase activity
MUA44_RS07800	COG0196	riboflavin kinase activity
MUA44_RS07805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MUA44_RS07810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MUA44_RS07830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MUA44_RS07835	COG1358	cellular component organization or biogenesis
MUA44_RS07840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MUA44_RS07845	COG0195	Participates in both transcription termination and antitermination
MUA44_RS07850	COG0779	Required for maturation of 30S ribosomal subunits
MUA44_RS07860	COG0442	prolyl-tRNA aminoacylation
MUA44_RS07870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MUA44_RS07875	COG4589	Belongs to the CDS family
MUA44_RS07885	COG0233	cytoplasmic translational termination
MUA44_RS07890	COG0528	UMP kinase activity
MUA44_RS07895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MUA44_RS07900	COG0052	Belongs to the universal ribosomal protein uS2 family
MUA44_RS07905	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MUA44_RS07910	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MUA44_RS07915	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MUA44_RS07920	COG4974	Belongs to the 'phage' integrase family
MUA44_RS07925	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MUA44_RS07930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUA44_RS07935	COG0758	DNA mediated transformation
MUA44_RS07945	COG0045	succinate-CoA ligase (ADP-forming) activity
MUA44_RS07955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUA44_RS07970	COG4485	Bacterial membrane protein, YfhO
MUA44_RS07995	COG0336	Belongs to the RNA methyltransferase TrmD family
MUA44_RS08000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MUA44_RS08005	COG0228	four-way junction DNA binding
MUA44_RS08035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MUA44_RS08040	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MUA44_RS08045	COG0552	protein localization to endoplasmic reticulum
MUA44_RS08050	COG1196	nuclear chromosome segregation
MUA44_RS08055	COG0571	ribonuclease III activity
MUA44_RS08060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUA44_RS08075	COG0416	fatty acid biosynthetic process
MUA44_RS08080	COG1349	DNA-binding transcription factor activity
MUA44_RS08090	COG1760	l-serine dehydratase
MUA44_RS08095	COG1760	l-serine dehydratase
MUA44_RS08100	COG1461	Dihydroxyacetone kinase
MUA44_RS08105	COG1302	Protein conserved in bacteria
MUA44_RS08120	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MUA44_RS08125	COG1162	GTPase activity
MUA44_RS08130	COG2124	cytochrome p450
MUA44_RS08145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MUA44_RS08150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUA44_RS08150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MUA44_RS08155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MUA44_RS08160	COG0242	peptide deformylase activity
MUA44_RS08165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MUA44_RS08170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MUA44_RS08175	COG1758	RNA polymerase activity
MUA44_RS08200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MUA44_RS08205	COG0284	orotidine-5'-phosphate decarboxylase activity
MUA44_RS08210	COG0167	dihydroorotate dehydrogenase activity
MUA44_RS08220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MUA44_RS08225	COG0505	Belongs to the CarA family
MUA44_RS08245	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MUA44_RS08250	COG0564	pseudouridine synthase activity
MUA44_RS08255	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MUA44_RS08260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MUA44_RS08265	COG3599	regulation of cell shape
MUA44_RS08275	COG0673	inositol 2-dehydrogenase activity
MUA44_RS08285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUA44_RS08290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUA44_RS08305	COG0762	integral membrane protein
MUA44_RS08310	COG1799	cell septum assembly
MUA44_RS08315	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MUA44_RS08325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MUA44_RS08330	COG0849	cell division
MUA44_RS08340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MUA44_RS08350	COG0768	penicillin binding
MUA44_RS08355	COG4839	cell division protein FtsL
MUA44_RS08360	COG0275	rRNA processing
MUA44_RS08365	COG2001	Belongs to the MraZ family
MUA44_RS08370	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MUA44_RS08375	COG0454	-acetyltransferase
MUA44_RS08380	COG1011	Hydrolase
MUA44_RS08390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUA44_RS08445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MUA44_RS08450	COG1053	succinate dehydrogenase
MUA44_RS08455	COG2009	succinate dehydrogenase
MUA44_RS08460	COG0322	excinuclease ABC activity
MUA44_RS08465	COG3118	belongs to the thioredoxin family
MUA44_RS08470	COG1193	negative regulation of DNA recombination
MUA44_RS08475	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MUA44_RS08475	COG1796	DNA polymerase
MUA44_RS08490	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUA44_RS08505	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MUA44_RS08510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUA44_RS08515	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MUA44_RS08535	COG0742	ribosomal rna small subunit methyltransferase
MUA44_RS08545	COG4471	UPF0298 protein
MUA44_RS08550	COG0584	glycerophosphoryl diester phosphodiesterase
MUA44_RS08555	COG3679	Belongs to the UPF0342 family
MUA44_RS08575	COG0109	protoheme IX farnesyltransferase activity
MUA44_RS08580	COG1612	heme a metabolic process
MUA44_RS08600	COG0772	Belongs to the SEDS family
MUA44_RS08605	COG4838	Belongs to the UPF0358 family
MUA44_RS08610	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MUA44_RS08615	COG4896	Protein conserved in bacteria
MUA44_RS08620	COG1902	pentaerythritol trinitrate reductase activity
MUA44_RS08625	COG1217	gtp-binding protein TYPA
MUA44_RS08635	COG0483	inositol monophosphate 1-phosphatase activity
MUA44_RS08640	COG4493	Belongs to the UPF0637 family
MUA44_RS08655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MUA44_RS08660	COG1177	transmembrane transport
MUA44_RS08670	COG3842	ATPase activity
MUA44_RS08680	COG4476	Belongs to the UPF0223 family
MUA44_RS08720	COG5503	Protein of unknown function (DUF1447)
MUA44_RS08725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MUA44_RS08730	COG0569	domain protein
MUA44_RS08735	COG1294	oxidase, subunit
MUA44_RS08740	COG1271	oxidase subunit
MUA44_RS08745	COG1393	Belongs to the ArsC family
MUA44_RS08750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUA44_RS08755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA44_RS08765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MUA44_RS08785	COG4172	Belongs to the ABC transporter superfamily
MUA44_RS08795	COG0151	Belongs to the GarS family
MUA44_RS08800	COG0138	bifunctional purine biosynthesis protein purh
MUA44_RS08810	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MUA44_RS08815	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MUA44_RS08825	COG0047	phosphoribosylformylglycinamidine synthase activity
MUA44_RS08830	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUA44_RS08835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MUA44_RS08840	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MUA44_RS08845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MUA44_RS08850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MUA44_RS08855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MUA44_RS08855	COG1017	nitric oxide dioxygenase activity
MUA44_RS08865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MUA44_RS08875	COG1845	cytochrome c oxidase, subunit III
MUA44_RS08880	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MUA44_RS08900	COG1134	teichoic acid transport
MUA44_RS08925	COG1215	transferase activity, transferring glycosyl groups
MUA44_RS08940	COG1682	transport, permease protein
MUA44_RS08945	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MUA44_RS08955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUA44_RS08960	COG1316	TRANSCRIPTIONal
MUA44_RS08990	COG3594	Acyltransferase
MUA44_RS08995	COG0436	Aminotransferase
MUA44_RS09000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MUA44_RS09010	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MUA44_RS09015	COG1169	isochorismate synthase
MUA44_RS09020	COG1575	Belongs to the MenA family. Type 1 subfamily
MUA44_RS09025	COG0390	transport system, permease component
MUA44_RS09030	COG4619	ABC transporter
MUA44_RS09050	COG4873	Protein conserved in bacteria
MUA44_RS09070	COG1388	LysM domain
MUA44_RS09070	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUA44_RS09105	COG0739	heme binding
MUA44_RS09160	COG4695	Portal protein
MUA44_RS09215	COG0756	dUTP diphosphatase activity
MUA44_RS09250	COG1484	DNA-dependent DNA replication
MUA44_RS09350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUA44_RS09375	COG0582	viral genome integration into host DNA
MUA44_RS09400	COG3266	domain, Protein
MUA44_RS09400	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
MUA44_RS09400	COG4932	domain protein
MUA44_RS09405	COG0737	Belongs to the 5'-nucleotidase family
MUA44_RS09415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUA44_RS09420	COG1696	Membrane protein involved in D-alanine export
MUA44_RS09430	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MUA44_RS09435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUA44_RS09440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUA44_RS09445	COG0861	Integral membrane protein TerC family
MUA44_RS09450	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MUA44_RS09460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MUA44_RS09465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUA44_RS09470	COG2814	Major facilitator Superfamily
MUA44_RS09480	COG3715	PTS system
MUA44_RS09485	COG3716	PTS system mannose fructose sorbose family IID component
MUA44_RS09490	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MUA44_RS09495	COG2382	esterase
MUA44_RS09505	COG0628	permease
MUA44_RS09515	COG0569	domain protein
MUA44_RS09515	COG0475	glutathione-regulated potassium exporter activity
MUA44_RS09520	COG2239	Acts as a magnesium transporter
MUA44_RS09525	COG0564	pseudouridine synthase activity
MUA44_RS09535	COG2357	RelA SpoT domain protein
MUA44_RS09550	COG2346	COG2346, Truncated hemoglobins
MUA44_RS09555	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MUA44_RS09560	COG1164	Oligoendopeptidase f
MUA44_RS09575	COG1393	Belongs to the ArsC family
MUA44_RS09580	COG0180	Tryptophanyl-tRNA synthetase
MUA44_RS09585	COG4166	transmembrane transport
MUA44_RS09590	COG4608	Belongs to the ABC transporter superfamily
MUA44_RS09595	COG0444	Belongs to the ABC transporter superfamily
MUA44_RS09600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUA44_RS09605	COG0601	transmembrane transport
MUA44_RS09635	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MUA44_RS09655	COG0561	phosphatase activity
MUA44_RS09660	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUA44_RS09670	COG0179	Fumarylacetoacetate (FAA) hydrolase
MUA44_RS09680	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MUA44_RS09695	COG0166	Belongs to the GPI family
MUA44_RS09700	COG0137	argininosuccinate synthase activity
MUA44_RS09710	COG0584	glycerophosphoryl diester phosphodiesterase
MUA44_RS09730	COG1012	belongs to the aldehyde dehydrogenase family
MUA44_RS09735	COG1098	S1 RNA binding domain
MUA44_RS09745	COG1278	Cold shock
MUA44_RS09755	COG1278	Cold shock
MUA44_RS09775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MUA44_RS09785	COG2111	Na H antiporter
MUA44_RS09785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUA44_RS09790	COG2111	Na H antiporter
MUA44_RS09795	COG1006	Multisubunit Na H antiporter MnhC subunit
MUA44_RS09800	COG0651	ATP synthesis coupled electron transport
MUA44_RS09805	COG1863	multisubunit Na H antiporter MnhE subunit
MUA44_RS09810	COG2212	antiporter activity
MUA44_RS09815	COG1320	monovalent cation:proton antiporter activity
MUA44_RS09825	COG2056	Na+-H+ antiporter family
MUA44_RS09830	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MUA44_RS09835	COG1252	NADH dehydrogenase
MUA44_RS09840	COG0316	Belongs to the HesB IscA family
MUA44_RS09845	COG4844	belongs to the
MUA44_RS09850	COG1252	NADH dehydrogenase
MUA44_RS09855	COG4837	Protein of unknown function (DUF1462)
MUA44_RS09860	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MUA44_RS09865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA44_RS09870	COG0647	UMP catabolic process
MUA44_RS09875	COG2445	Protein of unknown function DUF86
MUA44_RS09885	COG4470	Protein conserved in bacteria
MUA44_RS09890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MUA44_RS09895	COG0737	Belongs to the 5'-nucleotidase family
MUA44_RS09900	COG0730	response to heat
MUA44_RS09905	COG1801	Protein of unknown function DUF72
MUA44_RS09915	COG2070	2-Nitropropane dioxygenase
MUA44_RS09920	COG1253	flavin adenine dinucleotide binding
MUA44_RS09930	COG0719	Fe-S assembly protein
MUA44_RS09935	COG0822	iron-sulfur transferase activity
MUA44_RS09945	COG0719	Fe-S assembly protein
MUA44_RS09950	COG0396	ATPase activity
MUA44_RS09965	COG1464	Belongs to the NlpA lipoprotein family
MUA44_RS09970	COG1464	Belongs to the NlpA lipoprotein family
MUA44_RS09975	COG2011	ABC-type metal ion transport system permease component
MUA44_RS09990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MUA44_RS10000	COG1393	Belongs to the ArsC family
MUA44_RS10005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA44_RS10015	COG0710	3-dehydroquinate dehydratase activity
MUA44_RS10025	COG1764	response to oxidative stress
MUA44_RS10040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MUA44_RS10070	COG0557	exoribonuclease II activity
MUA44_RS10075	COG1647	Serine aminopeptidase, S33
MUA44_RS10080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MUA44_RS10095	COG0148	phosphopyruvate hydratase activity
MUA44_RS10100	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MUA44_RS10105	COG0149	triose-phosphate isomerase activity
MUA44_RS10110	COG0126	phosphoglycerate kinase activity
MUA44_RS10135	COG1090	epimerase
MUA44_RS10145	COG0740	serine-type endopeptidase activity
MUA44_RS10165	COG1481	regulation of sporulation
MUA44_RS10170	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MUA44_RS10175	COG1660	Displays ATPase and GTPase activities
MUA44_RS10190	COG0110	maltose O-acetyltransferase activity
MUA44_RS10195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MUA44_RS10200	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MUA44_RS10235	COG0653	protein targeting
MUA44_RS10240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MUA44_RS10250	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MUA44_RS10260	COG1739	Uncharacterized protein family UPF0029
MUA44_RS10265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUA44_RS10270	COG2199	diguanylate cyclase activity
MUA44_RS10285	COG2195	Cleaves the N-terminal amino acid of tripeptides
MUA44_RS10290	COG1929	Belongs to the glycerate kinase type-1 family
MUA44_RS10295	COG3118	belongs to the thioredoxin family
MUA44_RS10310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MUA44_RS10320	COG0494	nUDIX hydrolase
MUA44_RS10325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUA44_RS10330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUA44_RS10350	COG3104	oligopeptide transport
MUA44_RS10355	COG3104	oligopeptide transport
MUA44_RS10370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUA44_RS10375	COG1174	glycine betaine transport
MUA44_RS10380	COG1125	glycine betaine transport
MUA44_RS10380	COG0517	IMP dehydrogenase activity
MUA44_RS10385	COG0514	ATP-dependent DNA helicase (RecQ)
MUA44_RS10390	COG0488	(ABC) transporter
MUA44_RS10400	COG1368	sulfuric ester hydrolase activity
MUA44_RS10410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MUA44_RS10430	COG0512	Glutamine amidotransferase of anthranilate synthase
MUA44_RS10440	COG0720	synthase
MUA44_RS10445	COG0602	queuosine metabolic process
MUA44_RS10460	COG0463	Glycosyl transferase, family 2
MUA44_RS10465	COG1253	flavin adenine dinucleotide binding
MUA44_RS10470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA44_RS10470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA44_RS10470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA44_RS10475	COG1105	Belongs to the carbohydrate kinase PfkB family
MUA44_RS10480	COG1349	DNA-binding transcription factor activity
MUA44_RS10500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MUA44_RS10505	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA44_RS10525	COG0039	L-malate dehydrogenase activity
MUA44_RS10545	COG4989	oxidoreductase activity
MUA44_RS10550	COG0523	cobalamin synthesis protein
MUA44_RS10560	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MUA44_RS10565	COG4988	ABC transporter
MUA44_RS10570	COG1968	undecaprenyl-diphosphatase activity
MUA44_RS10580	COG1671	Belongs to the UPF0178 family
MUA44_RS10585	COG1611	Belongs to the LOG family
MUA44_RS10615	COG2839	Protein conserved in bacteria
MUA44_RS10620	COG2814	Major facilitator Superfamily
MUA44_RS10625	COG0583	DNA-binding transcription factor activity
MUA44_RS10640	COG0217	transcriptional regulatory protein
MUA44_RS10645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MUA44_RS10650	COG2022	thiamine diphosphate biosynthetic process
MUA44_RS10660	COG0352	thiamine-phosphate diphosphorylase activity
MUA44_RS10670	COG1388	LysM domain
MUA44_RS10670	COG3942	CHAP domain
MUA44_RS10675	COG0306	phosphate transporter
MUA44_RS10680	COG1392	Phosphate transport regulator
MUA44_RS10685	COG0577	efflux transmembrane transporter activity
MUA44_RS10690	COG1136	(ABC) transporter
MUA44_RS10700	COG0745	RESPONSE REGULATOR receiver
MUA44_RS10705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUA44_RS10720	COG3949	Membrane
MUA44_RS10725	COG0477	Major facilitator Superfamily
MUA44_RS10735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA44_RS10740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA44_RS10745	COG1120	ATPase activity
MUA44_RS10750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MUA44_RS10755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUA44_RS10775	COG1132	(ABC) transporter
MUA44_RS10780	COG1686	Belongs to the peptidase S11 family
MUA44_RS10785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MUA44_RS10790	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA44_RS10795	COG1682	transport, permease protein
MUA44_RS10805	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MUA44_RS10810	COG0110	maltose O-acetyltransferase activity
MUA44_RS10820	COG1475	DNA binding
MUA44_RS10825	COG0019	diaminopimelate decarboxylase activity
MUA44_RS10835	COG4264	IucA IucC family
MUA44_RS10840	COG4264	IucA IucC family
MUA44_RS10845	COG2814	Major facilitator Superfamily
MUA44_RS10850	COG4264	IucA IucC family
MUA44_RS10855	COG2423	ornithine cyclodeaminase activity
MUA44_RS10865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MUA44_RS10870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA44_RS10875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA44_RS10885	COG1121	(ABC) transporter
MUA44_RS10890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUA44_RS10895	COG0803	Belongs to the bacterial solute-binding protein 9 family
MUA44_RS10900	COG1320	monovalent cation:proton antiporter activity
MUA44_RS10905	COG2212	antiporter activity
MUA44_RS10910	COG1863	multisubunit Na H antiporter MnhE subunit
MUA44_RS10920	COG1006	Multisubunit Na H antiporter MnhC subunit
MUA44_RS10925	COG2111	Na H antiporter
MUA44_RS10930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUA44_RS10930	COG2111	Na H antiporter
MUA44_RS10975	COG2267	carboxylic ester hydrolase activity
MUA44_RS10980	COG0546	phosphoglycolate phosphatase activity
MUA44_RS10985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA44_RS10990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MUA44_RS10995	COG2822	iron ion transport
MUA44_RS11000	COG2837	iron assimilation
MUA44_RS11005	COG0672	)-iron permease
MUA44_RS11010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MUA44_RS11020	COG0018	arginyl-trna synthetase
MUA44_RS11035	COG1078	dGTPase activity
MUA44_RS11045	COG4844	belongs to the
MUA44_RS11105	COG0471	metal ion transport
MUA44_RS11135	COG0280	phosphate acetyltransferase
MUA44_RS11140	COG0095	Lipoate-protein ligase
MUA44_RS11145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA44_RS11160	COG2814	Major facilitator Superfamily
MUA44_RS11165	COG1566	PFAM secretion protein HlyD family protein
MUA44_RS11175	COG2311	Membrane
MUA44_RS11190	COG2363	Small membrane protein
MUA44_RS11200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MUA44_RS11220	COG0183	Belongs to the thiolase family
MUA44_RS11225	COG0318	PFAM AMP-dependent synthetase and ligase
MUA44_RS11230	COG0588	phosphoglycerate mutase activity
MUA44_RS11235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MUA44_RS11240	COG3314	Sporulation integral membrane protein YlbJ
MUA44_RS11245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MUA44_RS11255	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MUA44_RS11270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA44_RS11270	COG1263	PTS System
MUA44_RS11270	COG2190	(PTS) system
MUA44_RS11285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUA44_RS11290	COG1469	GTP cyclohydrolase I activity
MUA44_RS11295	COG1136	(ABC) transporter
MUA44_RS11295	COG0577	efflux transmembrane transporter activity
MUA44_RS11305	COG0561	phosphatase activity
MUA44_RS11315	COG1428	Deoxynucleoside kinase
MUA44_RS11320	COG1428	Deoxynucleoside kinase
MUA44_RS11325	COG0546	phosphoglycolate phosphatase activity
MUA44_RS11335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUA44_RS11340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUA44_RS11350	COG1473	amidohydrolase
MUA44_RS11355	COG3527	Alpha-acetolactate decarboxylase
MUA44_RS11360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MUA44_RS11365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MUA44_RS11370	COG0049	tRNA binding
MUA44_RS11375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MUA44_RS11385	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MUA44_RS11390	COG0085	RNA polymerase activity
MUA44_RS11395	COG2813	Specifically methylates the guanine in position
MUA44_RS11405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MUA44_RS11410	COG0081	regulation of translation
MUA44_RS11415	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MUA44_RS11420	COG0250	Participates in transcription elongation, termination and antitermination
MUA44_RS11425	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MUA44_RS11430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUA44_RS11450	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MUA44_RS11455	COG0215	cysteine-tRNA ligase activity
MUA44_RS11465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MUA44_RS11475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MUA44_RS11480	COG4956	integral membrane protein (PIN domain superfamily)
MUA44_RS11485	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MUA44_RS11490	COG0542	response to heat
MUA44_RS11495	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MUA44_RS11500	COG3880	PFAM UvrB UvrC protein
MUA44_RS11510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUA44_RS11520	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MUA44_RS11525	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MUA44_RS11530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUA44_RS11535	COG1289	transmembrane transporter activity
MUA44_RS11625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MUA44_RS11630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MUA44_RS11650	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MUA44_RS11655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MUA44_RS11670	COG1098	S1 RNA binding domain
MUA44_RS11680	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MUA44_RS11685	COG3956	TIGRFAM MazG family protein
MUA44_RS11690	COG2244	polysaccharide biosynthetic process
MUA44_RS11695	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MUA44_RS11700	COG0193	aminoacyl-tRNA hydrolase activity
MUA44_RS11710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MUA44_RS11715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MUA44_RS11720	COG2088	sporulation resulting in formation of a cellular spore
MUA44_RS11725	COG0251	oxidation-reduction process
MUA44_RS11730	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA44_RS11735	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MUA44_RS11740	COG4466	Protein conserved in bacteria
MUA44_RS11745	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MUA44_RS11750	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MUA44_RS11755	COG0084	hydrolase, TatD family'
MUA44_RS11765	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MUA44_RS11770	COG2827	Endonuclease containing a URI domain
MUA44_RS11775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MUA44_RS11780	COG4467	Involved in initiation control of chromosome replication
MUA44_RS11785	COG1774	PSP1 C-terminal conserved region
MUA44_RS11790	COG0470	DNA polymerase III
MUA44_RS11795	COG3870	Protein conserved in bacteria
MUA44_RS11800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MUA44_RS11805	COG1982	Orn Lys Arg decarboxylase major
MUA44_RS11825	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MUA44_RS11830	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MUA44_RS11835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MUA44_RS11850	COG2188	Transcriptional regulator
MUA44_RS11855	COG0366	Alpha amylase catalytic
MUA44_RS11860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA44_RS11860	COG1263	PTS System
MUA44_RS11875	COG0493	'glutamate synthase
MUA44_RS11880	COG0070	glutamate synthase
MUA44_RS11880	COG0069	glutamate synthase activity
MUA44_RS11880	COG0067	glutamate synthase
MUA44_RS11885	COG0583	DNA-binding transcription factor activity
MUA44_RS11900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MUA44_RS11915	COG1309	transcriptional regulator
MUA44_RS11925	COG0732	type I restriction modification DNA specificity domain
MUA44_RS11935	COG0626	cystathionine gamma-synthase activity
MUA44_RS11940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MUA44_RS11945	COG2272	Belongs to the type-B carboxylesterase lipase family
MUA44_RS11950	COG0733	neurotransmitter:sodium symporter activity
MUA44_RS11960	COG0745	RESPONSE REGULATOR receiver
MUA44_RS11965	COG2205	protein histidine kinase activity
MUA44_RS11970	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MUA44_RS11975	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MUA44_RS11985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MUA44_RS11990	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MUA44_RS11995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUA44_RS11995	COG0574	Belongs to the PEP-utilizing enzyme family
MUA44_RS12025	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MUA44_RS12035	COG1486	melibiose metabolic process
MUA44_RS12040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA44_RS12040	COG1263	PTS System
MUA44_RS12055	COG2814	Major facilitator Superfamily
MUA44_RS12070	COG1124	(ABC) transporter
MUA44_RS12075	COG0444	Belongs to the ABC transporter superfamily
MUA44_RS12080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MUA44_RS12085	COG0601	transmembrane transport
MUA44_RS12090	COG0747	negative chemotaxis
MUA44_RS12110	COG0346	lactoylglutathione lyase activity
MUA44_RS12145	COG1525	nuclease
MUA44_RS12165	COG0519	Catalyzes the synthesis of GMP from XMP
MUA44_RS12165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUA44_RS12170	COG0517	IMP dehydrogenase activity
MUA44_RS12170	COG0516	GMP reductase activity
MUA44_RS12175	COG2233	PERMEase
MUA44_RS12195	COG5183	chlorophyll binding
MUA44_RS12200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUA44_RS12205	COG1823	symporter activity
MUA44_RS12210	COG1136	(ABC) transporter
MUA44_RS12210	COG0577	efflux transmembrane transporter activity
MUA44_RS12225	COG0778	Nitroreductase
MUA44_RS12230	COG0450	alkyl hydroperoxide reductase
MUA44_RS12235	COG3634	alkyl hydroperoxide reductase activity
MUA44_RS12245	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MUA44_RS12255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MUA44_RS12260	COG2011	ABC-type metal ion transport system permease component
MUA44_RS12265	COG1464	Belongs to the NlpA lipoprotein family
MUA44_RS12270	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MUA44_RS12275	COG0753	catalase activity
MUA44_RS12295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MUA44_RS12305	COG0360	Binds together with S18 to 16S ribosomal RNA
MUA44_RS12325	COG0012	GTP binding
MUA44_RS12330	COG4481	Protein conserved in bacteria
MUA44_RS12335	COG0668	transmembrane transport
MUA44_RS12340	COG1475	DNA binding
MUA44_RS12345	COG0626	cystathionine gamma-synthase activity
MUA44_RS12350	COG0626	cystathionine gamma-synthase activity
MUA44_RS12355	COG0646	methionine synthase
MUA44_RS12355	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MUA44_RS12360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MUA44_RS12370	COG0829	nickel cation binding
MUA44_RS12380	COG0830	nickel cation binding
MUA44_RS12385	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MUA44_RS12395	COG0534	Mate efflux family protein
MUA44_RS12400	COG1966	Carbon starvation protein
MUA44_RS12410	COG2388	GCN5-related N-acetyl-transferase
MUA44_RS12415	COG1846	Transcriptional regulator
MUA44_RS12420	COG0346	lactoylglutathione lyase activity
MUA44_RS12425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MUA44_RS12430	COG0400	carboxylic ester hydrolase activity
MUA44_RS12445	COG1131	(ABC) transporter
MUA44_RS12480	COG0357	Ribosomal RNA small subunit methyltransferase G
MUA44_RS12485	COG0445	tRNA wobble uridine modification
MUA44_RS12490	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MUA44_RS12495	COG0594	ribonuclease P activity