locus-tag	class	description
KFV47_RS00005	COG0592	DNA-directed DNA polymerase activity
KFV47_RS00010	COG2501	S4 domain
KFV47_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFV47_RS00020	COG0187	DNA topoisomerase II activity
KFV47_RS00025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KFV47_RS00030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFV47_RS00035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KFV47_RS00055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFV47_RS00065	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KFV47_RS00070	COG0359	binds to the 23S rRNA
KFV47_RS00075	COG0305	Participates in initiation and elongation during chromosome replication
KFV47_RS00080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFV47_RS00095	COG0745	RESPONSE REGULATOR receiver
KFV47_RS00100	COG5002	protein histidine kinase activity
KFV47_RS00105	COG4863	YycH protein
KFV47_RS00115	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KFV47_RS00120	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFV47_RS00125	COG1396	sequence-specific DNA binding
KFV47_RS00150	COG2113	Glycine betaine
KFV47_RS00155	COG2409	Drug exporters of the RND superfamily
KFV47_RS00165	COG2205	protein histidine kinase activity
KFV47_RS00175	COG1131	(ABC) transporter
KFV47_RS00180	COG0745	RESPONSE REGULATOR receiver
KFV47_RS00185	COG0076	glutamate decarboxylase activity
KFV47_RS00225	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV47_RS00235	COG1215	transferase activity, transferring glycosyl groups
KFV47_RS00235	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV47_RS00275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFV47_RS00300	COG0640	Transcriptional regulator
KFV47_RS00305	COG2217	Heavy metal translocating P-type atpase
KFV47_RS00325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFV47_RS00325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFV47_RS00360	COG2003	Belongs to the UPF0758 family
KFV47_RS00385	COG0730	response to heat
KFV47_RS00395	COG1388	LysM domain
KFV47_RS00410	COG3425	synthase
KFV47_RS00415	COG0584	glycerophosphoryl diester phosphodiesterase
KFV47_RS00420	COG2030	dehydratase
KFV47_RS00445	COG1846	Transcriptional regulator
KFV47_RS00445	COG1940	carbohydrate kinase activity
KFV47_RS00455	COG2210	Belongs to the sulfur carrier protein TusA family
KFV47_RS00460	COG1937	Protein conserved in bacteria
KFV47_RS00500	COG2003	Belongs to the UPF0758 family
KFV47_RS00560	COG1396	sequence-specific DNA binding
KFV47_RS00580	COG2070	2-Nitropropane dioxygenase
KFV47_RS00590	COG0477	Major facilitator Superfamily
KFV47_RS00660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFV47_RS00665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFV47_RS00685	COG2217	Heavy metal translocating P-type atpase
KFV47_RS00690	COG2132	Multicopper oxidase
KFV47_RS00695	COG1388	LysM domain
KFV47_RS00705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFV47_RS00710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KFV47_RS00730	COG0640	Transcriptional regulator
KFV47_RS00750	COG0668	transmembrane transport
KFV47_RS00755	COG0561	phosphatase activity
KFV47_RS00785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFV47_RS00790	COG0579	oxidoreductase
KFV47_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
KFV47_RS00805	COG1755	Isoprenylcysteine carboxyl methyltransferase
KFV47_RS00815	COG2207	Transcriptional regulator
KFV47_RS00815	COG4753	response regulator
KFV47_RS00845	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KFV47_RS00845	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KFV47_RS00845	COG3583	domain protein
KFV47_RS00845	COG4932	domain protein
KFV47_RS00845	COG3583	domain protein
KFV47_RS00845	COG4932	domain protein
KFV47_RS00855	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFV47_RS00860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KFV47_RS00865	COG0156	8-amino-7-oxononanoate synthase activity
KFV47_RS00870	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KFV47_RS00895	COG0523	cobalamin synthesis protein
KFV47_RS00910	COG0803	Belongs to the bacterial solute-binding protein 9 family
KFV47_RS00920	COG0431	NADPH-dependent FMN reductase
KFV47_RS00920	COG3976	FMN-binding domain protein
KFV47_RS00920	COG1053	succinate dehydrogenase
KFV47_RS00930	COG1028	Short-chain dehydrogenase reductase Sdr
KFV47_RS00935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KFV47_RS00965	COG0601	transmembrane transport
KFV47_RS00975	COG0444	Belongs to the ABC transporter superfamily
KFV47_RS00980	COG1124	(ABC) transporter
KFV47_RS00990	COG1882	Formate acetyltransferase
KFV47_RS00995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KFV47_RS01000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFV47_RS01005	COG1114	Component of the transport system for branched-chain amino acids
KFV47_RS01010	COG1309	transcriptional regulator
KFV47_RS01015	COG3246	L-lysine catabolic process to acetate
KFV47_RS01020	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFV47_RS01055	COG1288	antiporter activity
KFV47_RS01060	COG0549	Belongs to the carbamate kinase family
KFV47_RS01080	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KFV47_RS01085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFV47_RS01095	COG2376	Dihydroxyacetone kinase
KFV47_RS01100	COG1461	Dihydroxyacetone kinase
KFV47_RS01105	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
KFV47_RS01120	COG2814	Major facilitator Superfamily
KFV47_RS01150	COG2814	Major facilitator Superfamily
KFV47_RS01165	COG2962	Rard protein
KFV47_RS01170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KFV47_RS01175	COG0471	metal ion transport
KFV47_RS01180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFV47_RS01185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFV47_RS01190	COG0022	dehydrogenase e1 component
KFV47_RS01195	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFV47_RS01220	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KFV47_RS01225	COG1054	Belongs to the UPF0176 family
KFV47_RS01230	COG3386	PFAM SMP-30 Gluconolaconase
KFV47_RS01235	COG2353	YceI-like domain
KFV47_RS01240	COG0579	oxidoreductase
KFV47_RS01265	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KFV47_RS01270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFV47_RS01275	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KFV47_RS01280	COG0131	Imidazoleglycerol-phosphate dehydratase
KFV47_RS01285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KFV47_RS01290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KFV47_RS01295	COG0107	imidazoleglycerol-phosphate synthase activity
KFV47_RS01300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFV47_RS01300	COG0140	phosphoribosyl-ATP diphosphatase activity
KFV47_RS01305	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KFV47_RS01310	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KFV47_RS01320	COG0726	polysaccharide deacetylase
KFV47_RS01345	COG2814	Major facilitator Superfamily
KFV47_RS01350	COG0737	Belongs to the 5'-nucleotidase family
KFV47_RS01365	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KFV47_RS01370	COG3639	organic phosphonate transmembrane transporter activity
KFV47_RS01390	COG0201	protein transport
KFV47_RS01400	COG1073	alpha beta
KFV47_RS01410	COG0653	protein targeting
KFV47_RS01415	COG0438	transferase activity, transferring glycosyl groups
KFV47_RS01440	COG2814	Major facilitator Superfamily
KFV47_RS01445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KFV47_RS01460	COG1764	response to oxidative stress
KFV47_RS01470	COG1705	Flagellar rod assembly protein muramidase FlgJ
KFV47_RS01470	COG3942	CHAP domain
KFV47_RS01480	COG1482	cell wall glycoprotein biosynthetic process
KFV47_RS01485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFV47_RS01485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFV47_RS01485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFV47_RS01490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFV47_RS01490	COG3711	transcriptional antiterminator
KFV47_RS01525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFV47_RS01530	COG3227	Zinc metalloprotease (Elastase)
KFV47_RS01535	COG1438	arginine binding
KFV47_RS01540	COG2235	arginine
KFV47_RS01545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFV47_RS01555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFV47_RS01565	COG2843	Capsule synthesis protein
KFV47_RS01570	COG3961	Belongs to the TPP enzyme family
KFV47_RS01595	COG1196	nuclear chromosome segregation
KFV47_RS01605	COG4195	phage-related replication protein
KFV47_RS01620	COG0702	epimerase
KFV47_RS01625	COG1785	Belongs to the alkaline phosphatase family
KFV47_RS01645	COG2205	protein histidine kinase activity
KFV47_RS01650	COG1136	(ABC) transporter
KFV47_RS01665	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFV47_RS01690	COG1846	Transcriptional regulator
KFV47_RS01700	COG0386	Belongs to the glutathione peroxidase family
KFV47_RS01705	COG0175	sulfate reduction
KFV47_RS01710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFV47_RS01715	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFV47_RS01730	COG0730	response to heat
KFV47_RS01735	COG2046	Belongs to the sulfate adenylyltransferase family
KFV47_RS01740	COG0529	Catalyzes the synthesis of activated sulfate
KFV47_RS01750	COG1328	CTP reductase activity
KFV47_RS01755	COG0602	queuosine metabolic process
KFV47_RS01760	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KFV47_RS01770	COG1510	regulation of RNA biosynthetic process
KFV47_RS01775	COG1012	belongs to the aldehyde dehydrogenase family
KFV47_RS01780	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KFV47_RS01785	COG1473	amidohydrolase
KFV47_RS01800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFV47_RS01805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFV47_RS01805	COG0574	Belongs to the PEP-utilizing enzyme family
KFV47_RS01810	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFV47_RS01815	COG0579	oxidoreductase
KFV47_RS01825	COG3588	fructose-bisphosphate aldolase
KFV47_RS01830	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFV47_RS01860	COG0531	amino acid
KFV47_RS01865	COG0583	DNA-binding transcription factor activity
KFV47_RS01870	COG0039	L-malate dehydrogenase activity
KFV47_RS01875	COG0028	Belongs to the TPP enzyme family
KFV47_RS01880	COG3527	Alpha-acetolactate decarboxylase
KFV47_RS01890	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFV47_RS01895	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KFV47_RS01900	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KFV47_RS01915	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFV47_RS01930	COG0167	dihydroorotate dehydrogenase activity
KFV47_RS01935	COG3001	Fructosamine kinase
KFV47_RS01940	COG1113	amino acid transport
KFV47_RS01955	COG0741	lytic transglycosylase activity
KFV47_RS01965	COG3942	CHAP domain
KFV47_RS01970	COG0436	Aminotransferase
KFV47_RS01980	COG2608	mercury ion transmembrane transporter activity
KFV47_RS01985	COG2217	Heavy metal translocating P-type atpase
KFV47_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
KFV47_RS02000	COG1012	belongs to the aldehyde dehydrogenase family
KFV47_RS02025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KFV47_RS02030	COG3425	synthase
KFV47_RS02050	COG0583	DNA-binding transcription factor activity
KFV47_RS02055	COG1380	Effector of murein hydrolase LrgA
KFV47_RS02060	COG1346	cytolysis
KFV47_RS02065	COG0028	Belongs to the TPP enzyme family
KFV47_RS02070	COG1263	PTS System
KFV47_RS02070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KFV47_RS02070	COG2190	(PTS) system
KFV47_RS02085	COG1063	alcohol dehydrogenase
KFV47_RS02095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KFV47_RS02110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFV47_RS02120	COG2843	Capsule synthesis protein
KFV47_RS02135	COG4975	Glucose uptake
KFV47_RS02140	COG1869	D-ribose catabolic process
KFV47_RS02150	COG1070	Carbohydrate kinase
KFV47_RS02165	COG1760	l-serine dehydratase
KFV47_RS02170	COG1760	l-serine dehydratase
KFV47_RS02195	COG3764	Sortase (surface protein transpeptidase)
KFV47_RS02205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFV47_RS02210	COG0778	Nitroreductase
KFV47_RS02215	COG1012	belongs to the aldehyde dehydrogenase family
KFV47_RS02225	COG2514	catechol 2,3-dioxygenase activity
KFV47_RS02240	COG1012	belongs to the aldehyde dehydrogenase family
KFV47_RS02245	COG3949	Membrane
KFV47_RS02255	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
KFV47_RS02260	COG0586	Pfam SNARE associated Golgi protein
KFV47_RS02265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFV47_RS02270	COG2022	thiamine diphosphate biosynthetic process
KFV47_RS02280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFV47_RS02290	COG2271	Major facilitator Superfamily
KFV47_RS02305	COG4876	unkown
KFV47_RS02310	COG2357	RelA SpoT domain protein
KFV47_RS02325	COG0789	Transcriptional regulator
KFV47_RS02330	COG2271	Major facilitator Superfamily
KFV47_RS02335	COG1802	Transcriptional regulator
KFV47_RS02345	COG2610	gluconate transmembrane transporter activity
KFV47_RS02350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KFV47_RS02355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFV47_RS02360	COG0438	transferase activity, transferring glycosyl groups
KFV47_RS02365	COG0494	nUDIX hydrolase
KFV47_RS02370	COG0556	nucleotide-excision repair
KFV47_RS02385	COG4221	oxidoreductase activity
KFV47_RS02390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFV47_RS02395	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFV47_RS02405	COG1028	Short-chain dehydrogenase reductase Sdr
KFV47_RS02415	COG1363	Peptidase, m42
KFV47_RS02425	COG0069	glutamate synthase activity
KFV47_RS02440	COG4619	ABC transporter
KFV47_RS02445	COG0390	transport system, permease component
KFV47_RS02450	COG2814	Major facilitator Superfamily
KFV47_RS02455	COG2272	Belongs to the type-B carboxylesterase lipase family
KFV47_RS02460	COG0531	amino acid
KFV47_RS02470	COG1063	alcohol dehydrogenase
KFV47_RS02490	COG1174	glycine betaine transport
KFV47_RS02495	COG1346	cytolysis
KFV47_RS02500	COG1380	Effector of murein hydrolase LrgA
KFV47_RS02505	COG3279	Response regulator of the LytR AlgR family
KFV47_RS02510	COG3275	phosphorelay sensor kinase activity
KFV47_RS02520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KFV47_RS02525	COG0706	membrane insertase activity
KFV47_RS02535	COG0531	amino acid
KFV47_RS02540	COG1113	amino acid transport
KFV47_RS02565	COG1929	Belongs to the glycerate kinase type-1 family
KFV47_RS02580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KFV47_RS02585	COG0588	phosphoglycerate mutase activity
KFV47_RS02595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KFV47_RS02600	COG0765	amino acid transport
KFV47_RS02605	COG1126	abc transporter atp-binding protein
KFV47_RS02615	COG2348	transferase activity, transferring amino-acyl groups
KFV47_RS02635	COG2116	formate transmembrane transporter activity
KFV47_RS02640	COG0454	-acetyltransferase
KFV47_RS02650	COG0747	negative chemotaxis
KFV47_RS02660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFV47_RS02665	COG2146	nitrite reductase [NAD(P)H] activity
KFV47_RS02675	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KFV47_RS02680	COG1140	nitrate reductase beta subunit
KFV47_RS02690	COG2181	nitrate reductase activity
KFV47_RS02700	COG4585	Histidine kinase
KFV47_RS02705	COG2197	response regulator
KFV47_RS02710	COG2223	nitrite transmembrane transporter activity
KFV47_RS02715	COG1846	Transcriptional regulator
KFV47_RS02740	COG3871	stress protein (general stress protein 26)
KFV47_RS02755	COG1263	PTS System
KFV47_RS02755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KFV47_RS02790	COG0604	alcohol dehydrogenase
KFV47_RS02795	COG0456	acetyltransferase
KFV47_RS02800	COG0463	Glycosyl transferase, family 2
KFV47_RS02800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV47_RS02810	COG0463	Glycosyl transferase, family 2
KFV47_RS02810	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV47_RS02815	COG1620	l-lactate permease
KFV47_RS02820	COG0438	transferase activity, transferring glycosyl groups
KFV47_RS02825	COG0579	oxidoreductase
KFV47_RS02830	COG3850	Histidine kinase
KFV47_RS02830	COG5002	protein histidine kinase activity
KFV47_RS02835	COG0745	RESPONSE REGULATOR receiver
KFV47_RS02840	COG0577	efflux transmembrane transporter activity
KFV47_RS02845	COG1136	(ABC) transporter
KFV47_RS02860	COG4640	response to antibiotic
KFV47_RS02865	COG2814	Major facilitator Superfamily
KFV47_RS02875	COG1566	PFAM secretion protein HlyD family protein
KFV47_RS02880	COG2814	Major facilitator Superfamily
KFV47_RS02890	COG0657	acetylesterase activity
KFV47_RS02905	COG0598	Magnesium transport protein CorA
KFV47_RS02910	COG1304	FMN binding
KFV47_RS02915	COG0786	glutamate:sodium symporter activity
KFV47_RS02935	COG2094	Belongs to the DNA glycosylase MPG family
KFV47_RS02945	COG1069	ribulokinase activity
KFV47_RS02950	COG2017	converts alpha-aldose to the beta-anomer
KFV47_RS02955	COG2258	MOSC domain
KFV47_RS02960	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFV47_RS02970	COG1266	CAAX protease self-immunity
KFV47_RS02975	COG0010	Belongs to the arginase family
KFV47_RS02980	COG1473	amidohydrolase
KFV47_RS02985	COG1028	Short-chain dehydrogenase reductase Sdr
KFV47_RS02990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KFV47_RS03020	COG1737	Transcriptional regulator
KFV47_RS03025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KFV47_RS03025	COG1263	PTS System
KFV47_RS03035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFV47_RS03060	COG1113	amino acid transport
KFV47_RS03070	COG1263	PTS System
KFV47_RS03070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KFV47_RS03075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KFV47_RS03090	COG1266	CAAX protease self-immunity
KFV47_RS03095	COG2378	regulation of single-species biofilm formation
KFV47_RS03100	COG0483	inositol monophosphate 1-phosphatase activity
KFV47_RS03105	COG1316	TRANSCRIPTIONal
KFV47_RS03125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFV47_RS03130	COG2076	Multidrug Resistance protein
KFV47_RS03135	COG2076	Multidrug Resistance protein
KFV47_RS03140	COG3942	CHAP domain
KFV47_RS03155	COG1757	Na H antiporter
KFV47_RS03160	COG3942	CHAP domain
KFV47_RS03185	COG0829	nickel cation binding
KFV47_RS03190	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KFV47_RS03195	COG0830	nickel cation binding
KFV47_RS03200	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KFV47_RS03205	COG0804	urea catabolic process
KFV47_RS03210	COG0832	Belongs to the urease beta subunit family
KFV47_RS03215	COG0831	urea catabolic process
KFV47_RS03225	COG1960	acyl-CoA dehydrogenase activity
KFV47_RS03235	COG1268	BioY protein
KFV47_RS03250	COG0725	ABC transporter, periplasmic molybdate-binding protein
KFV47_RS03255	COG4149	molybdate abc transporter
KFV47_RS03260	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KFV47_RS03265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFV47_RS03270	COG0521	Mo-molybdopterin cofactor biosynthetic process
KFV47_RS03275	COG0315	cyclic pyranopterin monophosphate synthase activity
KFV47_RS03280	COG0303	'Molybdopterin
KFV47_RS03290	COG0314	molybdopterin synthase activity
KFV47_RS03300	COG0746	molybdenum cofactor guanylyltransferase activity
KFV47_RS03305	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFV47_RS03325	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFV47_RS03330	COG0561	phosphatase activity
KFV47_RS03345	COG0542	response to heat
KFV47_RS03360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFV47_RS03375	COG0601	transmembrane transport
KFV47_RS03380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFV47_RS03385	COG0444	Belongs to the ABC transporter superfamily
KFV47_RS03390	COG4608	Belongs to the ABC transporter superfamily
KFV47_RS03395	COG4166	transmembrane transport
KFV47_RS03400	COG0180	Tryptophanyl-tRNA synthetase
KFV47_RS03405	COG1393	Belongs to the ArsC family
KFV47_RS03415	COG4862	establishment of competence for transformation
KFV47_RS03425	COG1164	Oligoendopeptidase f
KFV47_RS03430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KFV47_RS03435	COG2346	COG2346, Truncated hemoglobins
KFV47_RS03450	COG2357	RelA SpoT domain protein
KFV47_RS03455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KFV47_RS03460	COG0564	pseudouridine synthase activity
KFV47_RS03465	COG2239	Acts as a magnesium transporter
KFV47_RS03470	COG0475	glutathione-regulated potassium exporter activity
KFV47_RS03470	COG0569	domain protein
KFV47_RS03525	COG0628	permease
KFV47_RS03530	COG2382	esterase
KFV47_RS03535	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KFV47_RS03540	COG2814	Major facilitator Superfamily
KFV47_RS03545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KFV47_RS03550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFV47_RS03560	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFV47_RS03565	COG0861	Integral membrane protein TerC family
KFV47_RS03570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFV47_RS03575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFV47_RS03590	COG4873	Protein conserved in bacteria
KFV47_RS03650	COG2314	TM2 domain
KFV47_RS03655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KFV47_RS03660	COG1575	Belongs to the MenA family. Type 1 subfamily
KFV47_RS03665	COG1169	isochorismate synthase
KFV47_RS03670	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KFV47_RS03680	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KFV47_RS03685	COG0436	Aminotransferase
KFV47_RS03690	COG3594	Acyltransferase
KFV47_RS03715	COG1316	TRANSCRIPTIONal
KFV47_RS03730	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KFV47_RS03735	COG1845	cytochrome c oxidase, subunit III
KFV47_RS03740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFV47_RS03745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KFV47_RS03755	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFV47_RS03760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KFV47_RS03765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KFV47_RS03770	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KFV47_RS03775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFV47_RS03780	COG0047	phosphoribosylformylglycinamidine synthase activity
KFV47_RS03785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFV47_RS03790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KFV47_RS03795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KFV47_RS03800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFV47_RS03805	COG0138	bifunctional purine biosynthesis protein purh
KFV47_RS03810	COG0151	Belongs to the GarS family
KFV47_RS03815	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KFV47_RS03820	COG4172	Belongs to the ABC transporter superfamily
KFV47_RS03830	COG4716	Myosin-crossreactive antigen
KFV47_RS03855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFV47_RS03860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFV47_RS03870	COG1271	oxidase subunit
KFV47_RS03875	COG1294	oxidase, subunit
KFV47_RS03880	COG0569	domain protein
KFV47_RS03885	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KFV47_RS03890	COG5503	Protein of unknown function (DUF1447)
KFV47_RS03895	COG0242	peptide deformylase activity
KFV47_RS03905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFV47_RS03910	COG0022	dehydrogenase e1 component
KFV47_RS03915	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFV47_RS03925	COG4476	Belongs to the UPF0223 family
KFV47_RS03935	COG3842	ATPase activity
KFV47_RS03940	COG1176	ABC-type spermidine putrescine transport system, permease component I
KFV47_RS03965	COG1914	H( )-stimulated, divalent metal cation uptake system
KFV47_RS03970	COG4493	Belongs to the UPF0637 family
KFV47_RS03975	COG0483	inositol monophosphate 1-phosphatase activity
KFV47_RS03985	COG1217	gtp-binding protein TYPA
KFV47_RS04000	COG4896	Protein conserved in bacteria
KFV47_RS04005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KFV47_RS04010	COG4838	Belongs to the UPF0358 family
KFV47_RS04015	COG0772	Belongs to the SEDS family
KFV47_RS04025	COG1612	heme a metabolic process
KFV47_RS04030	COG0109	protoheme IX farnesyltransferase activity
KFV47_RS04040	COG2340	Cysteine-rich secretory protein family
KFV47_RS04045	COG3679	Belongs to the UPF0342 family
KFV47_RS04050	COG0584	glycerophosphoryl diester phosphodiesterase
KFV47_RS04055	COG4471	UPF0298 protein
KFV47_RS04065	COG0742	ribosomal rna small subunit methyltransferase
KFV47_RS04070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KFV47_RS04075	COG1323	Belongs to the UPF0348 family
KFV47_RS04085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KFV47_RS04095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFV47_RS04100	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFV47_RS04105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFV47_RS04105	COG0072	phenylalanine-tRNA ligase activity
KFV47_RS04110	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFV47_RS04115	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KFV47_RS04125	COG1796	DNA polymerase
KFV47_RS04125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KFV47_RS04130	COG1193	negative regulation of DNA recombination
KFV47_RS04135	COG3118	belongs to the thioredoxin family
KFV47_RS04140	COG0322	excinuclease ABC activity
KFV47_RS04145	COG2009	succinate dehydrogenase
KFV47_RS04150	COG1053	succinate dehydrogenase
KFV47_RS04155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KFV47_RS04160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KFV47_RS04165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFV47_RS04195	COG1011	Hydrolase
KFV47_RS04200	COG0454	-acetyltransferase
KFV47_RS04205	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KFV47_RS04210	COG2001	Belongs to the MraZ family
KFV47_RS04215	COG0275	rRNA processing
KFV47_RS04220	COG4839	cell division protein FtsL
KFV47_RS04225	COG0768	penicillin binding
KFV47_RS04230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFV47_RS04235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFV47_RS04240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFV47_RS04245	COG0849	cell division
KFV47_RS04250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KFV47_RS04255	COG1496	oxidoreductase activity
KFV47_RS04260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KFV47_RS04265	COG1799	cell septum assembly
KFV47_RS04270	COG0762	integral membrane protein
KFV47_RS04280	COG3599	regulation of cell shape
KFV47_RS04285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KFV47_RS04295	COG3942	CHAP domain
KFV47_RS04295	COG1388	LysM domain
KFV47_RS04300	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KFV47_RS04305	COG0564	pseudouridine synthase activity
KFV47_RS04310	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KFV47_RS04315	COG2233	PERMEase
KFV47_RS04320	COG0540	Belongs to the ATCase OTCase family
KFV47_RS04325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFV47_RS04330	COG0505	Belongs to the CarA family
KFV47_RS04335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFV47_RS04340	COG0284	orotidine-5'-phosphate decarboxylase activity
KFV47_RS04345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFV47_RS04365	COG0194	GDP metabolic process
KFV47_RS04370	COG1758	RNA polymerase activity
KFV47_RS04375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFV47_RS04380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFV47_RS04390	COG0242	peptide deformylase activity
KFV47_RS04395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFV47_RS04400	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KFV47_RS04400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFV47_RS04405	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFV47_RS04410	COG0631	protein serine/threonine phosphatase activity
KFV47_RS04420	COG1162	GTPase activity
KFV47_RS04425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KFV47_RS04435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KFV47_RS04440	COG1302	Protein conserved in bacteria
KFV47_RS04445	COG1461	Dihydroxyacetone kinase
KFV47_RS04450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFV47_RS04455	COG1349	DNA-binding transcription factor activity
KFV47_RS04460	COG0416	fatty acid biosynthetic process
KFV47_RS04470	COG1028	Short-chain dehydrogenase reductase Sdr
KFV47_RS04475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFV47_RS04480	COG0571	ribonuclease III activity
KFV47_RS04485	COG1196	nuclear chromosome segregation
KFV47_RS04490	COG0552	protein localization to endoplasmic reticulum
KFV47_RS04495	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KFV47_RS04500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFV47_RS04505	COG0228	four-way junction DNA binding
KFV47_RS04510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFV47_RS04515	COG0336	Belongs to the RNA methyltransferase TrmD family
KFV47_RS04520	COG0335	large ribosomal subunit rRNA binding
KFV47_RS04530	COG4485	Bacterial membrane protein, YfhO
KFV47_RS04540	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFV47_RS04545	COG0045	succinate-CoA ligase (ADP-forming) activity
KFV47_RS04550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KFV47_RS04555	COG0758	DNA mediated transformation
KFV47_RS04560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFV47_RS04565	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KFV47_RS04570	COG4974	Belongs to the 'phage' integrase family
KFV47_RS04575	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KFV47_RS04580	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KFV47_RS04585	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KFV47_RS04590	COG0052	Belongs to the universal ribosomal protein uS2 family
KFV47_RS04595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFV47_RS04600	COG0528	UMP kinase activity
KFV47_RS04605	COG0233	cytoplasmic translational termination
KFV47_RS04610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KFV47_RS04615	COG4589	Belongs to the CDS family
KFV47_RS04625	COG0442	prolyl-tRNA aminoacylation
KFV47_RS04630	COG2176	DNA-directed DNA polymerase activity
KFV47_RS04635	COG0779	Required for maturation of 30S ribosomal subunits
KFV47_RS04640	COG0195	Participates in both transcription termination and antitermination
KFV47_RS04645	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KFV47_RS04650	COG1358	cellular component organization or biogenesis
KFV47_RS04655	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KFV47_RS04660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KFV47_RS04665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KFV47_RS04670	COG0196	riboflavin kinase activity
KFV47_RS04675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KFV47_RS04680	COG1185	polyribonucleotide nucleotidyltransferase activity
KFV47_RS04685	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KFV47_RS04690	COG1674	ftsk spoiiie
KFV47_RS04695	COG2188	Transcriptional regulator
KFV47_RS04700	COG0612	Peptidase, M16
KFV47_RS04705	COG0612	Peptidase, M16
KFV47_RS04710	COG0300	oxidoreductase activity
KFV47_RS04725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFV47_RS04735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFV47_RS04740	COG1418	mRNA catabolic process
KFV47_RS04750	COG1692	metallophosphoesterase
KFV47_RS04755	COG0674	pyruvate-flavodoxin oxidoreductase activity
KFV47_RS04755	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KFV47_RS04760	COG1013	pyruvate-flavodoxin oxidoreductase activity
KFV47_RS04765	COG4195	phage-related replication protein
KFV47_RS04775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFV47_RS04780	COG4550	Control of competence regulator ComK, YlbF/YmcA
KFV47_RS04790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFV47_RS04795	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFV47_RS04800	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KFV47_RS04805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KFV47_RS04810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KFV47_RS04815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KFV47_RS04825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFV47_RS04830	COG1923	regulation of RNA biosynthetic process
KFV47_RS04835	COG0386	Belongs to the glutathione peroxidase family
KFV47_RS04840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFV47_RS04845	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KFV47_RS04850	COG0789	Transcriptional regulator
KFV47_RS04855	COG0174	glutamine synthetase
KFV47_RS04915	COG0629	single-stranded DNA binding
KFV47_RS04940	COG1595	DNA-templated transcription, initiation
KFV47_RS05060	COG4824	toxin secretion phage lysis holin
KFV47_RS05120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFV47_RS05125	COG1131	(ABC) transporter
KFV47_RS05135	COG4585	Histidine kinase
KFV47_RS05140	COG2197	response regulator
KFV47_RS05150	COG1525	nuclease
KFV47_RS05165	COG0527	aspartate kinase activity
KFV47_RS05170	COG0460	homoserine dehydrogenase
KFV47_RS05175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFV47_RS05180	COG0083	homoserine kinase activity
KFV47_RS05195	COG0833	amino acid
KFV47_RS05200	COG0753	catalase activity
KFV47_RS05210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFV47_RS05215	COG0516	GMP reductase activity
KFV47_RS05220	COG2340	Cysteine-rich secretory protein family
KFV47_RS05225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFV47_RS05235	COG4224	UPF0291 protein
KFV47_RS05240	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFV47_RS05250	COG4846	Membrane protein involved in cytochrome C biogenesis
KFV47_RS05255	COG0420	3'-5' exonuclease activity
KFV47_RS05260	COG0419	ATPase involved in DNA repair
KFV47_RS05265	COG1970	mechanosensitive ion channel activity
KFV47_RS05270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KFV47_RS05275	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KFV47_RS05280	COG0824	Thioesterase
KFV47_RS05290	COG4841	protein insertion into membrane
KFV47_RS05295	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KFV47_RS05300	COG0187	DNA topoisomerase II activity
KFV47_RS05305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KFV47_RS05310	COG1115	amino acid carrier protein
KFV47_RS05315	COG3711	transcriptional antiterminator
KFV47_RS05320	COG0628	permease
KFV47_RS05325	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KFV47_RS05325	COG0392	lysyltransferase activity
KFV47_RS05340	COG1942	4-Oxalocrotonate Tautomerase
KFV47_RS05345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFV47_RS05350	COG0287	Prephenate dehydrogenase
KFV47_RS05355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFV47_RS05360	COG0512	Glutamine amidotransferase of anthranilate synthase
KFV47_RS05360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFV47_RS05365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFV47_RS05370	COG0134	indole-3-glycerol-phosphate synthase activity
KFV47_RS05375	COG0135	phosphoribosylanthranilate isomerase activity
KFV47_RS05380	COG0133	tryptophan synthase activity
KFV47_RS05385	COG0159	tryptophan synthase activity
KFV47_RS05395	COG2348	transferase activity, transferring amino-acyl groups
KFV47_RS05400	COG2348	transferase activity, transferring amino-acyl groups
KFV47_RS05410	COG4607	ABC-type enterochelin transport system periplasmic component
KFV47_RS05445	COG0704	Plays a role in the regulation of phosphate uptake
KFV47_RS05450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KFV47_RS05455	COG0581	inorganic phosphate transmembrane transporter activity
KFV47_RS05460	COG0573	inorganic phosphate transmembrane transporter activity
KFV47_RS05465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFV47_RS05470	COG2996	Protein conserved in bacteria
KFV47_RS05475	COG0488	(ABC) transporter
KFV47_RS05480	COG0527	aspartate kinase activity
KFV47_RS05485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KFV47_RS05490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFV47_RS05495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KFV47_RS05500	COG2171	N-acyltransferase activity
KFV47_RS05505	COG1473	amidohydrolase
KFV47_RS05525	COG1131	(ABC) transporter
KFV47_RS05540	COG1278	Cold shock
KFV47_RS05550	COG1254	Belongs to the acylphosphatase family
KFV47_RS05560	COG3853	Toxic anion resistance protein (TelA)
KFV47_RS05565	COG1114	Component of the transport system for branched-chain amino acids
KFV47_RS05570	COG4548	von Willebrand factor, type A
KFV47_RS05575	COG0714	Associated with various cellular activities
KFV47_RS05600	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFV47_RS05605	COG0567	Dehydrogenase, E1 component
KFV47_RS05610	COG5002	protein histidine kinase activity
KFV47_RS05615	COG0745	RESPONSE REGULATOR receiver
KFV47_RS05620	COG1349	DNA-binding transcription factor activity
KFV47_RS05625	COG0534	Mate efflux family protein
KFV47_RS05635	COG0395	ABC-type sugar transport system, permease component
KFV47_RS05645	COG4209	transmembrane transport
KFV47_RS05650	COG3842	ATPase activity
KFV47_RS05655	COG0671	phosphoesterase, PA-phosphatase related
KFV47_RS05660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KFV47_RS05670	COG0793	Belongs to the peptidase S41A family
KFV47_RS05675	COG4479	Belongs to the UPF0346 family
KFV47_RS05680	COG2190	(PTS) system
KFV47_RS05685	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFV47_RS05710	COG1136	(ABC) transporter
KFV47_RS05725	COG1413	lyase activity
KFV47_RS05735	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KFV47_RS05750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFV47_RS05755	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KFV47_RS05765	COG0116	Belongs to the methyltransferase superfamily
KFV47_RS05775	COG3599	regulation of cell shape
KFV47_RS05780	COG4474	Belongs to the UPF0398 family
KFV47_RS05790	COG3331	DNA recombination
KFV47_RS05795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFV47_RS05795	COG4499	WXG100 protein secretion system (Wss), protein YukC
KFV47_RS05805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFV47_RS05810	COG3935	DnaD domain protein
KFV47_RS05815	COG0017	Asparaginyl-tRNA synthetase
KFV47_RS05820	COG1199	ATP-dependent helicase activity
KFV47_RS05820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFV47_RS05825	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFV47_RS05825	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFV47_RS05830	COG0617	tRNA 3'-terminal CCA addition
KFV47_RS05835	COG0438	transferase activity, transferring glycosyl groups
KFV47_RS05840	COG1694	Mazg nucleotide pyrophosphohydrolase
KFV47_RS05845	COG2738	Putative neutral zinc metallopeptidase
KFV47_RS05850	COG4347	Protein of unknown function (DUF1405)
KFV47_RS05855	COG5582	Belongs to the UPF0302 family
KFV47_RS05865	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KFV47_RS05870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KFV47_RS05875	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KFV47_RS05880	COG0105	UTP biosynthetic process
KFV47_RS05890	COG2226	methyltransferase
KFV47_RS05905	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFV47_RS05910	COG1160	GTP binding
KFV47_RS05915	COG0539	negative regulation of cytoplasmic translation
KFV47_RS05920	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFV47_RS05925	COG0252	asparaginase activity
KFV47_RS05930	COG0492	ferredoxin-NADP+ reductase activity
KFV47_RS05935	COG1388	LysM domain
KFV47_RS05940	COG0514	ATP-dependent DNA helicase (RecQ)
KFV47_RS05950	COG1141	Ferredoxin
KFV47_RS05965	COG0745	RESPONSE REGULATOR receiver
KFV47_RS05970	COG1187	pseudouridine synthase activity
KFV47_RS05975	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFV47_RS05980	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFV47_RS05985	COG1547	Domain of unknown function (DUF309)
KFV47_RS05990	COG4974	Belongs to the 'phage' integrase family
KFV47_RS05995	COG0735	belongs to the Fur family
KFV47_RS06000	COG0494	nUDIX hydrolase
KFV47_RS06005	COG0667	Aldo Keto reductase
KFV47_RS06010	COG1028	Short-chain dehydrogenase reductase Sdr
KFV47_RS06015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KFV47_RS06020	COG1234	tRNA 3'-trailer cleavage
KFV47_RS06025	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFV47_RS06035	COG0366	Alpha amylase catalytic
KFV47_RS06040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KFV47_RS06045	COG2195	Cleaves the N-terminal amino acid of tripeptides
KFV47_RS06055	COG4129	membrane
KFV47_RS06065	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFV47_RS06070	COG0022	dehydrogenase e1 component
KFV47_RS06075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFV47_RS06080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFV47_RS06085	COG0497	DNA recombination
KFV47_RS06090	COG1438	arginine binding
KFV47_RS06100	COG1722	exodeoxyribonuclease VII activity
KFV47_RS06105	COG1570	exodeoxyribonuclease VII activity
KFV47_RS06110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFV47_RS06115	COG1302	Protein conserved in bacteria
KFV47_RS06120	COG0439	Biotin carboxylase
KFV47_RS06125	COG0511	ligase activity, forming carbon-carbon bonds
KFV47_RS06130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFV47_RS06135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFV47_RS06140	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KFV47_RS06145	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KFV47_RS06150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFV47_RS06155	COG0006	proline dipeptidase activity
KFV47_RS06170	COG0095	Lipoate-protein ligase
KFV47_RS06175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFV47_RS06185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFV47_RS06190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFV47_RS06195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KFV47_RS06200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KFV47_RS06220	COG4537	Required for transformation and DNA binding
KFV47_RS06225	COG1459	type II secretion system
KFV47_RS06230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFV47_RS06240	COG0011	TIGRFAM Protein of
KFV47_RS06245	COG1940	carbohydrate kinase activity
KFV47_RS06250	COG4483	Protein conserved in bacteria
KFV47_RS06260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFV47_RS06265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KFV47_RS06270	COG0768	penicillin binding
KFV47_RS06275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFV47_RS06280	COG0735	belongs to the Fur family
KFV47_RS06285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KFV47_RS06290	COG1121	(ABC) transporter
KFV47_RS06295	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KFV47_RS06300	COG0513	Belongs to the DEAD box helicase family
KFV47_RS06305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KFV47_RS06310	COG2384	SAM-dependent methyltransferase
KFV47_RS06315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFV47_RS06320	COG0358	DNA primase activity
KFV47_RS06325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFV47_RS06330	COG0517	IMP dehydrogenase activity
KFV47_RS06335	COG0423	glycine-tRNA ligase activity
KFV47_RS06340	COG1381	Involved in DNA repair and RecF pathway recombination
KFV47_RS06345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KFV47_RS06350	COG0295	cytidine deaminase activity
KFV47_RS06355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KFV47_RS06360	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KFV47_RS06365	COG1702	phosphate starvation-inducible protein PhoH
KFV47_RS06375	COG4864	UPF0365 protein
KFV47_RS06380	COG1030	water channel activity
KFV47_RS06390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFV47_RS06395	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFV47_RS06400	COG2264	protein methyltransferase activity
KFV47_RS06405	COG0484	heat shock protein binding
KFV47_RS06410	COG0443	Heat shock 70 kDa protein
KFV47_RS06415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFV47_RS06420	COG1420	regulation of RNA biosynthetic process
KFV47_RS06425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFV47_RS06430	COG0481	GTPase activity
KFV47_RS06435	COG0268	Binds directly to 16S ribosomal RNA
KFV47_RS06440	COG1466	dna polymerase III delta subunit
KFV47_RS06445	COG2333	competence protein COMEC
KFV47_RS06445	COG0658	competence protein
KFV47_RS06450	COG2131	deaminase
KFV47_RS06460	COG2226	methyltransferase
KFV47_RS06465	COG0799	negative regulation of ribosome biogenesis
KFV47_RS06470	COG1713	HD superfamily hydrolase involved in NAD metabolism
KFV47_RS06475	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFV47_RS06480	COG1534	Rna-binding protein
KFV47_RS06485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KFV47_RS06490	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KFV47_RS06495	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KFV47_RS06500	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KFV47_RS06505	COG1914	H( )-stimulated, divalent metal cation uptake system
KFV47_RS06510	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KFV47_RS06515	COG0439	Biotin carboxylase
KFV47_RS06520	COG0511	ligase activity, forming carbon-carbon bonds
KFV47_RS06525	COG1984	allophanate hydrolase subunit 2
KFV47_RS06530	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KFV47_RS06540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFV47_RS06545	COG0572	uridine kinase
KFV47_RS06550	COG0826	peptidase U32
KFV47_RS06555	COG0826	peptidase U32
KFV47_RS06565	COG3906	Belongs to the UPF0473 family
KFV47_RS06570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFV47_RS06575	COG4472	Bacterial protein of unknown function (DUF965)
KFV47_RS06580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KFV47_RS06585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFV47_RS06595	COG0482	sulfurtransferase activity
KFV47_RS06600	COG1104	cysteine desulfurase activity
KFV47_RS06605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFV47_RS06615	COG1959	2 iron, 2 sulfur cluster binding
KFV47_RS06620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFV47_RS06625	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KFV47_RS06635	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KFV47_RS06640	COG0124	histidyl-tRNA synthetase
KFV47_RS06645	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFV47_RS06650	COG1490	D-aminoacyl-tRNA deacylase activity
KFV47_RS06655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFV47_RS06660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KFV47_RS06665	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KFV47_RS06665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KFV47_RS06670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFV47_RS06670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFV47_RS06675	COG1862	Preprotein translocase
KFV47_RS06680	COG0343	queuine tRNA-ribosyltransferase activity
KFV47_RS06685	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFV47_RS06690	COG2255	four-way junction helicase activity
KFV47_RS06695	COG0632	four-way junction helicase activity
KFV47_RS06700	COG4492	Belongs to the UPF0735 family
KFV47_RS06705	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFV47_RS06710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KFV47_RS06715	COG2868	ribosomal protein
KFV47_RS06720	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KFV47_RS06730	COG1792	Involved in formation and maintenance of cell shape
KFV47_RS06750	COG2003	Belongs to the UPF0758 family
KFV47_RS06760	COG0285	dihydrofolate synthase activity
KFV47_RS06765	COG0525	valine-tRNA ligase activity
KFV47_RS06770	COG2818	Glycosylase
KFV47_RS06780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFV47_RS06785	COG0113	porphobilinogen synthase activity
KFV47_RS06795	COG0181	hydroxymethylbilane synthase activity
KFV47_RS06805	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFV47_RS06810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KFV47_RS06815	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFV47_RS06820	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFV47_RS06830	COG4112	unkown
KFV47_RS06835	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFV47_RS06840	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KFV47_RS06845	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFV47_RS06850	COG0833	amino acid
KFV47_RS06855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KFV47_RS06860	COG1484	DNA-dependent DNA replication
KFV47_RS06865	COG3611	Membrane attachment protein
KFV47_RS06870	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFV47_RS06875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFV47_RS06885	COG0237	dephospho-CoA kinase activity
KFV47_RS06890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFV47_RS06895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFV47_RS06895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFV47_RS06900	COG5002	protein histidine kinase activity
KFV47_RS06905	COG0745	RESPONSE REGULATOR receiver
KFV47_RS06910	COG0538	isocitrate dehydrogenase activity
KFV47_RS06915	COG0372	Belongs to the citrate synthase family
KFV47_RS06920	COG1113	amino acid transport
KFV47_RS06925	COG0469	pyruvate kinase activity
KFV47_RS06930	COG0205	6-phosphofructokinase activity
KFV47_RS06935	COG0825	malonyl-CoA metabolic process
KFV47_RS06940	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFV47_RS06945	COG0281	malic enzyme
KFV47_RS06950	COG0587	DNA-directed DNA polymerase activity
KFV47_RS06955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KFV47_RS06960	COG4109	DRTGG domain
KFV47_RS06970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KFV47_RS06975	COG0006	proline dipeptidase activity
KFV47_RS06980	COG0686	Belongs to the AlaDH PNT family
KFV47_RS06985	COG0589	response to stress
KFV47_RS06995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KFV47_RS07000	COG0827	DNA restriction-modification system
KFV47_RS07005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KFV47_RS07015	COG0301	tRNA thio-modification
KFV47_RS07025	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KFV47_RS07030	COG1956	GAF domain-containing protein
KFV47_RS07035	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KFV47_RS07040	COG0584	glycerophosphoryl diester phosphodiesterase
KFV47_RS07045	COG1764	response to oxidative stress
KFV47_RS07050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFV47_RS07055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFV47_RS07065	COG1263	PTS System
KFV47_RS07065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KFV47_RS07070	COG0204	Acyl-transferase
KFV47_RS07075	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFV47_RS07080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFV47_RS07090	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KFV47_RS07095	COG1609	Transcriptional regulator
KFV47_RS07100	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KFV47_RS07100	COG1605	Chorismate mutase
KFV47_RS07110	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KFV47_RS07115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFV47_RS07120	COG1674	ftsk spoiiie
KFV47_RS07125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFV47_RS07130	COG4848	Belongs to the UPF0354 family
KFV47_RS07135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFV47_RS07140	COG1363	Peptidase, m42
KFV47_RS07150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KFV47_RS07155	COG0510	thiamine kinase activity
KFV47_RS07160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFV47_RS07165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFV47_RS07175	COG1187	pseudouridine synthase activity
KFV47_RS07180	COG2244	polysaccharide biosynthetic process
KFV47_RS07185	COG2081	HI0933 family
KFV47_RS07200	COG0495	leucyl-tRNA aminoacylation
KFV47_RS07205	COG2814	Major facilitator Superfamily
KFV47_RS07210	COG1242	4 iron, 4 sulfur cluster binding
KFV47_RS07215	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KFV47_RS07230	COG2267	carboxylic ester hydrolase activity
KFV47_RS07235	COG0506	proline dehydrogenase activity
KFV47_RS07240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFV47_RS07245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFV47_RS07245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFV47_RS07255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFV47_RS07255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFV47_RS07265	COG3266	domain, Protein
KFV47_RS07265	COG4193	domain, Protein
KFV47_RS07265	COG5632	N-Acetylmuramoyl-L-alanine amidase
KFV47_RS07290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFV47_RS07300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFV47_RS07305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFV47_RS07320	COG0656	L-ascorbic acid biosynthetic process
KFV47_RS07330	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFV47_RS07335	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KFV47_RS07340	COG1506	peptidase
KFV47_RS07345	COG0494	nUDIX hydrolase
KFV47_RS07350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KFV47_RS07360	COG0318	PFAM AMP-dependent synthetase and ligase
KFV47_RS07465	COG3942	CHAP domain
KFV47_RS07620	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KFV47_RS07625	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFV47_RS07630	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFV47_RS07635	COG2329	Antibiotic biosynthesis monooxygenase
KFV47_RS07645	COG4473	ABC transporter
KFV47_RS07650	COG1131	(ABC) transporter
KFV47_RS07655	COG0537	adenosine 5'-monophosphoramidase activity
KFV47_RS07670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFV47_RS07680	COG3481	metal-dependent phosphohydrolase, HD sub domain
KFV47_RS07690	COG0420	3'-5' exonuclease activity
KFV47_RS07695	COG3679	Belongs to the UPF0342 family
KFV47_RS07700	COG4399	Belongs to the UPF0754 family
KFV47_RS07710	COG2197	response regulator
KFV47_RS07715	COG2203	Gaf domain
KFV47_RS07715	COG4585	Histidine kinase
KFV47_RS07725	COG0114	fumarate hydratase activity
KFV47_RS07750	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFV47_RS07760	COG1126	abc transporter atp-binding protein
KFV47_RS07765	COG0765	amino acid transport
KFV47_RS07795	COG4824	toxin secretion phage lysis holin
KFV47_RS07895	COG1595	DNA-templated transcription, initiation
KFV47_RS08165	COG0735	belongs to the Fur family
KFV47_RS08170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFV47_RS08175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFV47_RS08180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFV47_RS08185	COG4129	membrane
KFV47_RS08195	COG3557	Belongs to the UPF0374 family
KFV47_RS08210	COG1988	membrane-bound metal-dependent
KFV47_RS08220	COG1388	LysM domain
KFV47_RS08220	COG1134	teichoic acid transport
KFV47_RS08230	COG2137	regulation of response to DNA damage stimulus
KFV47_RS08235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFV47_RS08240	COG0693	protein deglycase activity
KFV47_RS08250	COG0535	radical SAM domain protein
KFV47_RS08255	COG1607	acyl-coa hydrolase
KFV47_RS08260	COG2309	aminopeptidase activity
KFV47_RS08265	COG4840	Belongs to the UPF0435 family
KFV47_RS08270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFV47_RS08280	COG1295	ribonuclease BN
KFV47_RS08285	COG2197	response regulator
KFV47_RS08290	COG4585	Histidine kinase
KFV47_RS08305	COG0024	Methionine aminopeptidase
KFV47_RS08310	COG4129	membrane
KFV47_RS08330	COG1528	Iron-storage protein
KFV47_RS08340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFV47_RS08350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KFV47_RS08355	COG1597	lipid kinase activity
KFV47_RS08360	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFV47_RS08365	COG0154	amidase activity
KFV47_RS08370	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFV47_RS08375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFV47_RS08380	COG4851	CamS sex pheromone cAM373 precursor
KFV47_RS08385	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFV47_RS08390	COG0210	DNA helicase
KFV47_RS08395	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KFV47_RS08400	COG4496	protein, YerC YecD
KFV47_RS08405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KFV47_RS08415	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KFV47_RS08420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFV47_RS08425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KFV47_RS08435	COG0077	Prephenate dehydratase
KFV47_RS08445	COG1335	isochorismatase
KFV47_RS08450	COG1227	inorganic diphosphatase activity
KFV47_RS08455	COG1012	belongs to the aldehyde dehydrogenase family
KFV47_RS08460	COG2706	6-phosphogluconolactonase activity
KFV47_RS08465	COG3682	Transcriptional regulator
KFV47_RS08495	COG4974	Belongs to the 'phage' integrase family
KFV47_RS08545	COG1131	(ABC) transporter
KFV47_RS08555	COG1131	(ABC) transporter
KFV47_RS08560	COG1725	Transcriptional regulator
KFV47_RS08680	COG3617	BRO family, N-terminal domain
KFV47_RS08695	COG0582	viral genome integration into host DNA
KFV47_RS08700	COG0459	protein refolding
KFV47_RS08705	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KFV47_RS08745	COG3279	Response regulator of the LytR AlgR family
KFV47_RS08750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFV47_RS08755	COG1621	beta-fructofuranosidase activity
KFV47_RS08760	COG1609	Transcriptional regulator
KFV47_RS08765	COG0004	ammonium transporteR
KFV47_RS08770	COG0425	Belongs to the sulfur carrier protein TusA family
KFV47_RS08780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFV47_RS08820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFV47_RS08845	COG1780	Probably involved in ribonucleotide reductase function
KFV47_RS08885	COG0270	DNA (cytosine-5-)-methyltransferase activity
KFV47_RS08890	COG2226	methyltransferase
KFV47_RS08955	COG0587	DNA-directed DNA polymerase activity
KFV47_RS08960	COG0587	DNA-directed DNA polymerase activity
KFV47_RS08990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KFV47_RS09035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFV47_RS09170	COG0456	acetyltransferase
KFV47_RS09270	COG2887	Belongs to the helicase family. UvrD subfamily
KFV47_RS09370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFV47_RS09380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFV47_RS09410	COG4373	Mu-like prophage FluMu protein gp28
KFV47_RS09480	COG0582	viral genome integration into host DNA
KFV47_RS09495	COG2433	Pfam Transposase IS66
KFV47_RS09535	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFV47_RS09535	COG1388	LysM domain
KFV47_RS09575	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KFV47_RS09580	COG0488	(ABC) transporter
KFV47_RS09585	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFV47_RS09590	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KFV47_RS09595	COG0456	acetyltransferase
KFV47_RS09600	COG1214	PFAM Peptidase M22, glycoprotease
KFV47_RS09605	COG0802	atpase or kinase
KFV47_RS09610	COG0129	dihydroxy-acid dehydratase activity
KFV47_RS09615	COG0028	Belongs to the TPP enzyme family
KFV47_RS09625	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFV47_RS09630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFV47_RS09635	COG0473	3-isopropylmalate dehydrogenase activity
KFV47_RS09640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFV47_RS09645	COG0066	3-isopropylmalate dehydratase activity
KFV47_RS09650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFV47_RS09680	COG3091	SprT-like family
KFV47_RS09685	COG2183	response to ionizing radiation
KFV47_RS09690	COG1191	sigma factor activity
KFV47_RS09705	COG2208	phosphoserine phosphatase activity
KFV47_RS09710	COG2337	Toxic component of a toxin-antitoxin (TA) module
KFV47_RS09720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KFV47_RS09725	COG0736	holo-[acyl-carrier-protein] synthase activity
KFV47_RS09730	COG3402	PFAM membrane-flanked domain
KFV47_RS09735	COG3428	Bacterial PH domain
KFV47_RS09745	COG0513	Belongs to the DEAD box helicase family
KFV47_RS09750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFV47_RS09755	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFV47_RS09760	COG0772	Belongs to the SEDS family
KFV47_RS09775	COG1937	Protein conserved in bacteria
KFV47_RS09780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFV47_RS09785	COG1418	mRNA catabolic process
KFV47_RS09790	COG0706	membrane insertase activity
KFV47_RS09795	COG0352	thiamine-phosphate diphosphorylase activity
KFV47_RS09800	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KFV47_RS09810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KFV47_RS09815	COG1388	LysM domain
KFV47_RS09820	COG0629	single-stranded DNA binding
KFV47_RS09830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFV47_RS09835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFV47_RS09845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFV47_RS09850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KFV47_RS09855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KFV47_RS09860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFV47_RS09865	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFV47_RS09870	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFV47_RS09880	COG0356	it plays a direct role in the translocation of protons across the membrane
KFV47_RS09890	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KFV47_RS09895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KFV47_RS09900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KFV47_RS09905	COG4475	Protein of unknown function (DUF436)
KFV47_RS09910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFV47_RS09915	COG0009	L-threonylcarbamoyladenylate synthase
KFV47_RS09920	COG2890	protein-(glutamine-N5) methyltransferase activity
KFV47_RS09925	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFV47_RS09930	COG1435	thymidine kinase activity
KFV47_RS09935	COG0254	rRNA binding
KFV47_RS09940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFV47_RS09945	COG1012	belongs to the aldehyde dehydrogenase family
KFV47_RS09950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFV47_RS09955	COG0191	fructose-bisphosphate aldolase activity
KFV47_RS09965	COG0504	CTP synthase activity
KFV47_RS09970	COG3343	RNA polymerase activity
KFV47_RS09980	COG5146	pantothenate kinase activity
KFV47_RS10000	COG1854	S-ribosylhomocysteine lyase activity
KFV47_RS10010	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KFV47_RS10015	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KFV47_RS10020	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KFV47_RS10025	COG0813	purine-nucleoside phosphorylase activity
KFV47_RS10030	COG0783	Belongs to the Dps family
KFV47_RS10050	COG1482	cell wall glycoprotein biosynthetic process
KFV47_RS10055	COG0702	epimerase
KFV47_RS10060	COG0640	Transcriptional regulator
KFV47_RS10080	COG0561	phosphatase activity
KFV47_RS10085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFV47_RS10090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFV47_RS10100	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KFV47_RS10150	COG0489	protein tyrosine kinase activity
KFV47_RS10155	COG2814	Major facilitator Superfamily
KFV47_RS10175	COG4284	Utp--glucose-1-phosphate uridylyltransferase
KFV47_RS10180	COG1988	membrane-bound metal-dependent
KFV47_RS10190	COG2329	Antibiotic biosynthesis monooxygenase
KFV47_RS10195	COG3314	Sporulation integral membrane protein YlbJ
KFV47_RS10200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFV47_RS10205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFV47_RS10210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KFV47_RS10215	COG3457	Alanine racemase
KFV47_RS10220	COG4264	IucA IucC family
KFV47_RS10225	COG2814	Major facilitator Superfamily
KFV47_RS10230	COG4264	IucA IucC family
KFV47_RS10235	COG1302	Protein conserved in bacteria
KFV47_RS10250	COG0604	alcohol dehydrogenase
KFV47_RS10255	COG2130	NADP-dependent
KFV47_RS10260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFV47_RS10270	COG2723	6-phospho-beta-galactosidase activity
KFV47_RS10275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KFV47_RS10275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KFV47_RS10280	COG1447	Phosphotransferase system cellobiose-specific component IIA
KFV47_RS10285	COG3684	Belongs to the aldolase LacD family
KFV47_RS10290	COG1105	Belongs to the carbohydrate kinase PfkB family
KFV47_RS10295	COG0698	ribose 5-phosphate isomerase
KFV47_RS10300	COG0698	ribose 5-phosphate isomerase
KFV47_RS10305	COG1349	DNA-binding transcription factor activity
KFV47_RS10310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KFV47_RS10315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KFV47_RS10320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KFV47_RS10325	COG0101	tRNA pseudouridine synthase activity
KFV47_RS10335	COG1122	ATPase activity
KFV47_RS10340	COG1122	ATPase activity
KFV47_RS10345	COG0203	ribosomal protein L17
KFV47_RS10350	COG0202	RNA polymerase activity
KFV47_RS10355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KFV47_RS10360	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KFV47_RS10365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KFV47_RS10370	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KFV47_RS10375	COG0563	adenylate kinase activity
KFV47_RS10380	COG0201	protein transport
KFV47_RS10385	COG0200	Binds to the 23S rRNA
KFV47_RS10390	COG1841	ribosomal large subunit assembly
KFV47_RS10395	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KFV47_RS10400	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KFV47_RS10405	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KFV47_RS10410	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KFV47_RS10415	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFV47_RS10420	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFV47_RS10425	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFV47_RS10430	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KFV47_RS10435	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFV47_RS10445	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KFV47_RS10450	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KFV47_RS10455	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KFV47_RS10460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KFV47_RS10465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFV47_RS10470	COG0089	rRNA binding
KFV47_RS10475	COG0088	Forms part of the polypeptide exit tunnel
KFV47_RS10480	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KFV47_RS10495	COG2252	PERMEase
KFV47_RS10500	COG0551	DNA topoisomerase type I activity
KFV47_RS10500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFV47_RS10505	COG4975	Glucose uptake
KFV47_RS10510	COG1028	Short-chain dehydrogenase reductase Sdr
KFV47_RS10530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFV47_RS10535	COG2348	transferase activity, transferring amino-acyl groups
KFV47_RS10550	COG2814	Major facilitator Superfamily
KFV47_RS10575	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFV47_RS10580	COG1074	ATP-dependent DNA helicase activity
KFV47_RS10585	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KFV47_RS10600	COG0398	Pfam SNARE associated Golgi protein
KFV47_RS10605	COG0166	Belongs to the GPI family
KFV47_RS10610	COG0137	argininosuccinate synthase activity
KFV47_RS10615	COG0165	Argininosuccinate lyase
KFV47_RS10620	COG0584	glycerophosphoryl diester phosphodiesterase
KFV47_RS10630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFV47_RS10640	COG1902	pentaerythritol trinitrate reductase activity
KFV47_RS10645	COG1098	S1 RNA binding domain
KFV47_RS10650	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFV47_RS10660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFV47_RS10660	COG2111	Na H antiporter
KFV47_RS10665	COG2111	Na H antiporter
KFV47_RS10670	COG1006	Multisubunit Na H antiporter MnhC subunit
KFV47_RS10675	COG0651	ATP synthesis coupled electron transport
KFV47_RS10680	COG1863	multisubunit Na H antiporter MnhE subunit
KFV47_RS10685	COG2212	antiporter activity
KFV47_RS10690	COG1320	monovalent cation:proton antiporter activity
KFV47_RS10700	COG2050	protein possibly involved in aromatic compounds catabolism
KFV47_RS10705	COG2056	Na+-H+ antiporter family
KFV47_RS10710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFV47_RS10715	COG1252	NADH dehydrogenase
KFV47_RS10720	COG0316	Belongs to the HesB IscA family
KFV47_RS10725	COG4844	belongs to the
KFV47_RS10730	COG1252	NADH dehydrogenase
KFV47_RS10735	COG4837	Protein of unknown function (DUF1462)
KFV47_RS10740	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KFV47_RS10745	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KFV47_RS10750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFV47_RS10755	COG1696	Membrane protein involved in D-alanine export
KFV47_RS10760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFV47_RS10770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFV47_RS10775	COG0647	UMP catabolic process
KFV47_RS10780	COG2445	Protein of unknown function DUF86
KFV47_RS10790	COG4470	Protein conserved in bacteria
KFV47_RS10795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KFV47_RS10800	COG0737	Belongs to the 5'-nucleotidase family
KFV47_RS10805	COG0730	response to heat
KFV47_RS10810	COG1801	Protein of unknown function DUF72
KFV47_RS10815	COG1253	flavin adenine dinucleotide binding
KFV47_RS10830	COG0719	Fe-S assembly protein
KFV47_RS10835	COG0822	iron-sulfur transferase activity
KFV47_RS10840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFV47_RS10845	COG0719	Fe-S assembly protein
KFV47_RS10850	COG0396	ATPase activity
KFV47_RS10860	COG3237	CsbD-like
KFV47_RS10870	COG1464	Belongs to the NlpA lipoprotein family
KFV47_RS10875	COG2011	ABC-type metal ion transport system permease component
KFV47_RS10880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFV47_RS10890	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KFV47_RS10895	COG0509	glycine decarboxylation via glycine cleavage system
KFV47_RS10900	COG1393	Belongs to the ArsC family
KFV47_RS10905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFV47_RS10915	COG0710	3-dehydroquinate dehydratase activity
KFV47_RS10920	COG1764	response to oxidative stress
KFV47_RS10965	COG4195	phage-related replication protein
KFV47_RS10980	COG1278	Cold shock
KFV47_RS11010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFV47_RS11050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFV47_RS11055	COG0557	exoribonuclease II activity
KFV47_RS11060	COG1647	Serine aminopeptidase, S33
KFV47_RS11065	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFV47_RS11075	COG0148	phosphopyruvate hydratase activity
KFV47_RS11080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KFV47_RS11085	COG0149	triose-phosphate isomerase activity
KFV47_RS11090	COG0126	phosphoglycerate kinase activity
KFV47_RS11095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFV47_RS11115	COG1090	epimerase
KFV47_RS11125	COG0740	serine-type endopeptidase activity
KFV47_RS11135	COG1481	regulation of sporulation
KFV47_RS11140	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KFV47_RS11145	COG1660	Displays ATPase and GTPase activities
KFV47_RS11150	COG0492	ferredoxin-NADP+ reductase activity
KFV47_RS11165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KFV47_RS11170	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KFV47_RS11175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFV47_RS11180	COG0556	nucleotide-excision repair
KFV47_RS11195	COG1388	LysM domain
KFV47_RS11195	COG3942	CHAP domain
KFV47_RS11205	COG0653	protein targeting
KFV47_RS11210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KFV47_RS11215	COG1040	competence protein
KFV47_RS11220	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KFV47_RS11230	COG1739	Uncharacterized protein family UPF0029
KFV47_RS11235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFV47_RS11240	COG2199	diguanylate cyclase activity
KFV47_RS11255	COG2195	Cleaves the N-terminal amino acid of tripeptides
KFV47_RS11260	COG1929	Belongs to the glycerate kinase type-1 family
KFV47_RS11280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFV47_RS11295	COG4604	ABC transporter, ATP-binding protein
KFV47_RS11305	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFV47_RS11315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFV47_RS11320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFV47_RS11325	COG1780	Probably involved in ribonucleotide reductase function
KFV47_RS11335	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFV47_RS11340	COG3104	oligopeptide transport
KFV47_RS11350	COG1597	lipid kinase activity
KFV47_RS11355	COG1454	alcohol dehydrogenase
KFV47_RS11355	COG1012	belongs to the aldehyde dehydrogenase family
KFV47_RS11360	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KFV47_RS11365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFV47_RS11370	COG1174	glycine betaine transport
KFV47_RS11380	COG0514	ATP-dependent DNA helicase (RecQ)
KFV47_RS11385	COG0488	(ABC) transporter
KFV47_RS11400	COG1368	sulfuric ester hydrolase activity
KFV47_RS11410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KFV47_RS11425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFV47_RS11435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFV47_RS11440	COG0720	synthase
KFV47_RS11445	COG0602	queuosine metabolic process
KFV47_RS11470	COG0745	RESPONSE REGULATOR receiver
KFV47_RS11475	COG5002	protein histidine kinase activity
KFV47_RS11480	COG0463	Glycosyl transferase, family 2
KFV47_RS11485	COG0656	L-ascorbic acid biosynthetic process
KFV47_RS11490	COG1253	flavin adenine dinucleotide binding
KFV47_RS11495	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KFV47_RS11500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFV47_RS11500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFV47_RS11500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFV47_RS11505	COG1105	Belongs to the carbohydrate kinase PfkB family
KFV47_RS11510	COG1349	DNA-binding transcription factor activity
KFV47_RS11515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KFV47_RS11540	COG0415	Belongs to the DNA photolyase family
KFV47_RS11550	COG0471	metal ion transport
KFV47_RS11555	COG0039	L-malate dehydrogenase activity
KFV47_RS11575	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KFV47_RS11580	COG4988	ABC transporter
KFV47_RS11585	COG1968	undecaprenyl-diphosphatase activity
KFV47_RS11600	COG1671	Belongs to the UPF0178 family
KFV47_RS11605	COG1611	Belongs to the LOG family
KFV47_RS11630	COG2839	Protein conserved in bacteria
KFV47_RS11635	COG2814	Major facilitator Superfamily
KFV47_RS11640	COG0583	DNA-binding transcription factor activity
KFV47_RS11660	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KFV47_RS11670	COG0217	transcriptional regulatory protein
KFV47_RS11690	COG3942	CHAP domain
KFV47_RS11690	COG1388	LysM domain
KFV47_RS11695	COG0306	phosphate transporter
KFV47_RS11700	COG1392	Phosphate transport regulator
KFV47_RS11705	COG0577	efflux transmembrane transporter activity
KFV47_RS11710	COG1136	(ABC) transporter
KFV47_RS11715	COG2205	protein histidine kinase activity
KFV47_RS11720	COG0745	RESPONSE REGULATOR receiver
KFV47_RS11725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFV47_RS11740	COG3949	Membrane
KFV47_RS11750	COG1120	ATPase activity
KFV47_RS11755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KFV47_RS11760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFV47_RS11770	COG1132	(ABC) transporter
KFV47_RS11775	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KFV47_RS11785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV47_RS11790	COG1682	transport, permease protein
KFV47_RS11795	COG1134	teichoic acid transport
KFV47_RS11800	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KFV47_RS11810	COG1321	iron dependent repressor
KFV47_RS11815	COG1121	(ABC) transporter
KFV47_RS11820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KFV47_RS11825	COG0803	Belongs to the bacterial solute-binding protein 9 family
KFV47_RS11835	COG1320	monovalent cation:proton antiporter activity
KFV47_RS11840	COG2212	antiporter activity
KFV47_RS11845	COG1863	multisubunit Na H antiporter MnhE subunit
KFV47_RS11850	COG0651	ATP synthesis coupled electron transport
KFV47_RS11855	COG1006	Multisubunit Na H antiporter MnhC subunit
KFV47_RS11860	COG2111	Na H antiporter
KFV47_RS11865	COG2111	Na H antiporter
KFV47_RS11865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFV47_RS11895	COG0596	Alpha beta hydrolase
KFV47_RS11915	COG0546	phosphoglycolate phosphatase activity
KFV47_RS11920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFV47_RS11925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KFV47_RS11935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFV47_RS11940	COG0018	arginyl-trna synthetase
KFV47_RS11955	COG1064	alcohol dehydrogenase
KFV47_RS11960	COG3875	lactate racemase activity
KFV47_RS11965	COG1606	tRNA processing
KFV47_RS11970	COG1691	(AIR) carboxylase
KFV47_RS11975	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KFV47_RS11985	COG1078	dGTPase activity
KFV47_RS11995	COG0667	Aldo Keto reductase
KFV47_RS12010	COG1388	LysM domain
KFV47_RS12010	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFV47_RS12020	COG4195	phage-related replication protein
KFV47_RS12060	COG4824	toxin secretion phage lysis holin
KFV47_RS12155	COG5484	DNA packaging
KFV47_RS12155	COG3728	DNA packaging
KFV47_RS12165	COG3331	DNA recombination
KFV47_RS12185	COG0756	dUTP diphosphatase activity
KFV47_RS12280	COG3561	AntA/AntB antirepressor
KFV47_RS12310	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFV47_RS12310	COG1388	LysM domain
KFV47_RS12320	COG4195	phage-related replication protein
KFV47_RS12360	COG4824	toxin secretion phage lysis holin
KFV47_RS12455	COG3728	DNA packaging
KFV47_RS12455	COG5484	DNA packaging
KFV47_RS12465	COG3331	DNA recombination
KFV47_RS12485	COG0756	dUTP diphosphatase activity
KFV47_RS12580	COG3561	AntA/AntB antirepressor
KFV47_RS12615	COG4844	belongs to the
KFV47_RS12635	COG0095	Lipoate-protein ligase
KFV47_RS12640	COG0280	phosphate acetyltransferase
KFV47_RS12645	COG3253	May function as heme-dependent peroxidase
KFV47_RS12670	COG0531	amino acid
KFV47_RS12675	COG2363	Small membrane protein
KFV47_RS12685	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFV47_RS12695	COG0351	phosphomethylpyrimidine kinase
KFV47_RS12715	COG0183	Belongs to the thiolase family
KFV47_RS12720	COG0318	PFAM AMP-dependent synthetase and ligase
KFV47_RS12735	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KFV47_RS12740	COG0363	glucosamine-6-phosphate deaminase activity
KFV47_RS12750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KFV47_RS12755	COG1469	GTP cyclohydrolase I activity
KFV47_RS12780	COG0431	NADPH-dependent FMN reductase
KFV47_RS12785	COG0561	phosphatase activity
KFV47_RS12795	COG1428	Deoxynucleoside kinase
KFV47_RS12800	COG1428	Deoxynucleoside kinase
KFV47_RS12805	COG1028	Short-chain dehydrogenase reductase Sdr
KFV47_RS12810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFV47_RS12815	COG0546	phosphoglycolate phosphatase activity
KFV47_RS12820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV47_RS12825	COG1063	alcohol dehydrogenase
KFV47_RS12830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFV47_RS12835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFV47_RS12840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFV47_RS12860	COG1473	amidohydrolase
KFV47_RS12865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFV47_RS12870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFV47_RS12880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KFV47_RS12890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFV47_RS12895	COG0085	RNA polymerase activity
KFV47_RS12900	COG2813	Specifically methylates the guanine in position
KFV47_RS12905	COG0222	ribosome binding
KFV47_RS12910	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KFV47_RS12915	COG0081	regulation of translation
KFV47_RS12920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFV47_RS12925	COG0250	Participates in transcription elongation, termination and antitermination
KFV47_RS12930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFV47_RS12935	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KFV47_RS12945	COG3688	RNA-binding protein containing a PIN domain
KFV47_RS12950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFV47_RS12955	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KFV47_RS12960	COG0215	cysteine-tRNA ligase activity
KFV47_RS12965	COG1045	serine acetyltransferase
KFV47_RS12970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFV47_RS12975	COG4956	integral membrane protein (PIN domain superfamily)
KFV47_RS12980	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KFV47_RS12985	COG0542	response to heat
KFV47_RS12990	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KFV47_RS12995	COG3880	PFAM UvrB UvrC protein
KFV47_RS13000	COG4463	regulation of RNA biosynthetic process
KFV47_RS13005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFV47_RS13015	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KFV47_RS13020	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KFV47_RS13025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFV47_RS13095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KFV47_RS13100	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFV47_RS13105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFV47_RS13110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFV47_RS13115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KFV47_RS13120	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFV47_RS13125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFV47_RS13130	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFV47_RS13135	COG0037	tRNA processing
KFV47_RS13140	COG1098	S1 RNA binding domain
KFV47_RS13150	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KFV47_RS13155	COG3956	TIGRFAM MazG family protein
KFV47_RS13160	COG2244	polysaccharide biosynthetic process
KFV47_RS13165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFV47_RS13170	COG0193	aminoacyl-tRNA hydrolase activity
KFV47_RS13175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KFV47_RS13180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFV47_RS13185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFV47_RS13190	COG2088	sporulation resulting in formation of a cellular spore
KFV47_RS13195	COG0251	oxidation-reduction process
KFV47_RS13200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KFV47_RS13205	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KFV47_RS13210	COG4466	Protein conserved in bacteria
KFV47_RS13215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFV47_RS13220	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KFV47_RS13225	COG0084	hydrolase, TatD family'
KFV47_RS13230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFV47_RS13230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFV47_RS13235	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KFV47_RS13240	COG2827	Endonuclease containing a URI domain
KFV47_RS13245	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KFV47_RS13250	COG4467	Involved in initiation control of chromosome replication
KFV47_RS13255	COG1774	PSP1 C-terminal conserved region
KFV47_RS13260	COG0470	DNA polymerase III
KFV47_RS13265	COG3870	Protein conserved in bacteria
KFV47_RS13270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFV47_RS13275	COG1982	Orn Lys Arg decarboxylase major
KFV47_RS13300	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KFV47_RS13305	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KFV47_RS13310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KFV47_RS13330	COG2855	membrane
KFV47_RS13335	COG0583	DNA-binding transcription factor activity
KFV47_RS13345	COG0493	'glutamate synthase
KFV47_RS13350	COG0069	glutamate synthase activity
KFV47_RS13350	COG0067	glutamate synthase
KFV47_RS13350	COG0070	glutamate synthase
KFV47_RS13355	COG0583	DNA-binding transcription factor activity
KFV47_RS13380	COG0438	transferase activity, transferring glycosyl groups
KFV47_RS13385	COG3942	CHAP domain
KFV47_RS13385	COG1388	LysM domain
KFV47_RS13395	COG2011	ABC-type metal ion transport system permease component
KFV47_RS13400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFV47_RS13405	COG0626	cystathionine gamma-synthase activity
KFV47_RS13410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KFV47_RS13420	COG0733	neurotransmitter:sodium symporter activity
KFV47_RS13430	COG1647	Serine aminopeptidase, S33
KFV47_RS13445	COG5609	conserved protein (DUF2294)
KFV47_RS13450	COG3002	Belongs to the UPF0753 family
KFV47_RS13455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFV47_RS13475	COG0523	cobalamin synthesis protein
KFV47_RS13515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFV47_RS13515	COG0519	Catalyzes the synthesis of GMP from XMP
KFV47_RS13520	COG0516	GMP reductase activity
KFV47_RS13520	COG0517	IMP dehydrogenase activity
KFV47_RS13525	COG2233	PERMEase
KFV47_RS13530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KFV47_RS13545	COG5183	chlorophyll binding
KFV47_RS13550	COG1823	symporter activity
KFV47_RS13555	COG0778	Nitroreductase
KFV47_RS13565	COG0450	alkyl hydroperoxide reductase
KFV47_RS13570	COG3634	alkyl hydroperoxide reductase activity
KFV47_RS13590	COG1280	lysine exporter protein (LysE YggA)
KFV47_RS13605	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KFV47_RS13615	COG0360	Binds together with S18 to 16S ribosomal RNA
KFV47_RS13630	COG0012	GTP binding
KFV47_RS13635	COG4481	Protein conserved in bacteria
KFV47_RS13640	COG0668	transmembrane transport
KFV47_RS13645	COG1475	DNA binding
KFV47_RS13650	COG0626	cystathionine gamma-synthase activity
KFV47_RS13655	COG0626	cystathionine gamma-synthase activity
KFV47_RS13660	COG0646	methionine synthase
KFV47_RS13660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFV47_RS13665	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KFV47_RS13675	COG0183	Belongs to the thiolase family
KFV47_RS13690	COG1476	TRANSCRIPTIONal
KFV47_RS13730	COG1136	(ABC) transporter
KFV47_RS13735	COG0577	efflux transmembrane transporter activity
KFV47_RS13750	COG0577	efflux transmembrane transporter activity
KFV47_RS13755	COG1136	(ABC) transporter
KFV47_RS13790	COG1475	DNA binding
KFV47_RS13795	COG0357	Ribosomal RNA small subunit methyltransferase G
KFV47_RS13800	COG0445	tRNA wobble uridine modification
KFV47_RS13805	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KFV47_RS13810	COG0594	ribonuclease P activity
KFV47_RS13820	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFV47_RS14085	COG2314	TM2 domain