locus-tag	class	description
KFV34_RS00085	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFV34_RS00090	COG0592	DNA-directed DNA polymerase activity
KFV34_RS00095	COG2501	S4 domain
KFV34_RS00100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFV34_RS00105	COG0187	DNA topoisomerase II activity
KFV34_RS00110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KFV34_RS00115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFV34_RS00120	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KFV34_RS00140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFV34_RS00150	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KFV34_RS00155	COG0359	binds to the 23S rRNA
KFV34_RS00160	COG0305	Participates in initiation and elongation during chromosome replication
KFV34_RS00165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFV34_RS00180	COG0745	RESPONSE REGULATOR receiver
KFV34_RS00185	COG5002	protein histidine kinase activity
KFV34_RS00190	COG4863	YycH protein
KFV34_RS00200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KFV34_RS00205	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFV34_RS00210	COG1396	sequence-specific DNA binding
KFV34_RS00235	COG2113	Glycine betaine
KFV34_RS00240	COG2409	Drug exporters of the RND superfamily
KFV34_RS00250	COG2205	protein histidine kinase activity
KFV34_RS00260	COG1131	(ABC) transporter
KFV34_RS00265	COG0745	RESPONSE REGULATOR receiver
KFV34_RS00270	COG0076	glutamate decarboxylase activity
KFV34_RS00310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV34_RS00320	COG1215	transferase activity, transferring glycosyl groups
KFV34_RS00320	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV34_RS00360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFV34_RS00385	COG0640	Transcriptional regulator
KFV34_RS00390	COG2217	Heavy metal translocating P-type atpase
KFV34_RS00410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFV34_RS00410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFV34_RS00445	COG2003	Belongs to the UPF0758 family
KFV34_RS00470	COG0730	response to heat
KFV34_RS00480	COG1388	LysM domain
KFV34_RS00495	COG3425	synthase
KFV34_RS00500	COG0584	glycerophosphoryl diester phosphodiesterase
KFV34_RS00505	COG2030	dehydratase
KFV34_RS00530	COG1940	carbohydrate kinase activity
KFV34_RS00530	COG1846	Transcriptional regulator
KFV34_RS00540	COG2210	Belongs to the sulfur carrier protein TusA family
KFV34_RS00545	COG1937	Protein conserved in bacteria
KFV34_RS00585	COG2003	Belongs to the UPF0758 family
KFV34_RS00645	COG1396	sequence-specific DNA binding
KFV34_RS00670	COG2070	2-Nitropropane dioxygenase
KFV34_RS00680	COG0477	Major facilitator Superfamily
KFV34_RS00750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFV34_RS00755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFV34_RS00775	COG2217	Heavy metal translocating P-type atpase
KFV34_RS00780	COG2132	Multicopper oxidase
KFV34_RS00785	COG1388	LysM domain
KFV34_RS00795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFV34_RS00800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KFV34_RS00820	COG0640	Transcriptional regulator
KFV34_RS00840	COG0668	transmembrane transport
KFV34_RS00845	COG0561	phosphatase activity
KFV34_RS00875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFV34_RS00880	COG0579	oxidoreductase
KFV34_RS00885	COG1028	Short-chain dehydrogenase reductase Sdr
KFV34_RS00895	COG1755	Isoprenylcysteine carboxyl methyltransferase
KFV34_RS00905	COG4753	response regulator
KFV34_RS00905	COG2207	Transcriptional regulator
KFV34_RS00935	COG4932	domain protein
KFV34_RS00935	COG3583	domain protein
KFV34_RS00935	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KFV34_RS00935	COG3583	domain protein
KFV34_RS00935	COG4932	domain protein
KFV34_RS00935	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KFV34_RS00945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFV34_RS00950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KFV34_RS00955	COG0156	8-amino-7-oxononanoate synthase activity
KFV34_RS00960	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KFV34_RS00985	COG0523	cobalamin synthesis protein
KFV34_RS01000	COG0803	Belongs to the bacterial solute-binding protein 9 family
KFV34_RS01010	COG1053	succinate dehydrogenase
KFV34_RS01010	COG3976	FMN-binding domain protein
KFV34_RS01010	COG0431	NADPH-dependent FMN reductase
KFV34_RS01020	COG1028	Short-chain dehydrogenase reductase Sdr
KFV34_RS01025	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KFV34_RS01055	COG0601	transmembrane transport
KFV34_RS01065	COG0444	Belongs to the ABC transporter superfamily
KFV34_RS01070	COG1124	(ABC) transporter
KFV34_RS01080	COG1882	Formate acetyltransferase
KFV34_RS01085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KFV34_RS01090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFV34_RS01095	COG1114	Component of the transport system for branched-chain amino acids
KFV34_RS01100	COG1309	transcriptional regulator
KFV34_RS01105	COG3246	L-lysine catabolic process to acetate
KFV34_RS01110	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFV34_RS01145	COG1288	antiporter activity
KFV34_RS01150	COG0549	Belongs to the carbamate kinase family
KFV34_RS01155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFV34_RS01170	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KFV34_RS01175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFV34_RS01185	COG2376	Dihydroxyacetone kinase
KFV34_RS01190	COG1461	Dihydroxyacetone kinase
KFV34_RS01195	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
KFV34_RS01210	COG2814	Major facilitator Superfamily
KFV34_RS01240	COG2814	Major facilitator Superfamily
KFV34_RS01255	COG2962	Rard protein
KFV34_RS01260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KFV34_RS01265	COG0471	metal ion transport
KFV34_RS01270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFV34_RS01275	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFV34_RS01280	COG0022	dehydrogenase e1 component
KFV34_RS01285	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFV34_RS01310	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KFV34_RS01315	COG1054	Belongs to the UPF0176 family
KFV34_RS01320	COG3386	PFAM SMP-30 Gluconolaconase
KFV34_RS01325	COG2353	YceI-like domain
KFV34_RS01330	COG0579	oxidoreductase
KFV34_RS01355	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KFV34_RS01360	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFV34_RS01365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KFV34_RS01370	COG0131	Imidazoleglycerol-phosphate dehydratase
KFV34_RS01375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KFV34_RS01380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KFV34_RS01385	COG0107	imidazoleglycerol-phosphate synthase activity
KFV34_RS01390	COG0140	phosphoribosyl-ATP diphosphatase activity
KFV34_RS01390	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFV34_RS01395	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KFV34_RS01400	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KFV34_RS01410	COG0726	polysaccharide deacetylase
KFV34_RS01435	COG2814	Major facilitator Superfamily
KFV34_RS01440	COG0737	Belongs to the 5'-nucleotidase family
KFV34_RS01455	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KFV34_RS01460	COG3639	organic phosphonate transmembrane transporter activity
KFV34_RS01480	COG0201	protein transport
KFV34_RS01490	COG1073	alpha beta
KFV34_RS01500	COG0653	protein targeting
KFV34_RS01505	COG0438	transferase activity, transferring glycosyl groups
KFV34_RS01530	COG2814	Major facilitator Superfamily
KFV34_RS01535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KFV34_RS01550	COG1764	response to oxidative stress
KFV34_RS01560	COG1705	Flagellar rod assembly protein muramidase FlgJ
KFV34_RS01560	COG3942	CHAP domain
KFV34_RS01570	COG1482	cell wall glycoprotein biosynthetic process
KFV34_RS01575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFV34_RS01575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFV34_RS01575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFV34_RS01580	COG3711	transcriptional antiterminator
KFV34_RS01580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFV34_RS01615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFV34_RS01620	COG3227	Zinc metalloprotease (Elastase)
KFV34_RS01625	COG1438	arginine binding
KFV34_RS01630	COG2235	arginine
KFV34_RS01635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFV34_RS01645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFV34_RS01655	COG2843	Capsule synthesis protein
KFV34_RS01660	COG3961	Belongs to the TPP enzyme family
KFV34_RS01685	COG1196	nuclear chromosome segregation
KFV34_RS01695	COG4195	phage-related replication protein
KFV34_RS01710	COG0702	epimerase
KFV34_RS01715	COG1785	Belongs to the alkaline phosphatase family
KFV34_RS01735	COG2205	protein histidine kinase activity
KFV34_RS01740	COG1136	(ABC) transporter
KFV34_RS01755	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFV34_RS01780	COG1846	Transcriptional regulator
KFV34_RS01790	COG0386	Belongs to the glutathione peroxidase family
KFV34_RS01795	COG0175	sulfate reduction
KFV34_RS01800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFV34_RS01805	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFV34_RS01820	COG0730	response to heat
KFV34_RS01825	COG2046	Belongs to the sulfate adenylyltransferase family
KFV34_RS01830	COG0529	Catalyzes the synthesis of activated sulfate
KFV34_RS01840	COG1328	CTP reductase activity
KFV34_RS01845	COG0602	queuosine metabolic process
KFV34_RS01850	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KFV34_RS01860	COG1510	regulation of RNA biosynthetic process
KFV34_RS01865	COG1012	belongs to the aldehyde dehydrogenase family
KFV34_RS01870	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KFV34_RS01875	COG1473	amidohydrolase
KFV34_RS01890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFV34_RS01895	COG0574	Belongs to the PEP-utilizing enzyme family
KFV34_RS01895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFV34_RS01900	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFV34_RS01905	COG0579	oxidoreductase
KFV34_RS01915	COG3588	fructose-bisphosphate aldolase
KFV34_RS01920	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFV34_RS01950	COG0531	amino acid
KFV34_RS01955	COG0583	DNA-binding transcription factor activity
KFV34_RS01960	COG0039	L-malate dehydrogenase activity
KFV34_RS01965	COG0028	Belongs to the TPP enzyme family
KFV34_RS01970	COG3527	Alpha-acetolactate decarboxylase
KFV34_RS01980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFV34_RS01985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KFV34_RS01990	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KFV34_RS02005	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFV34_RS02020	COG0167	dihydroorotate dehydrogenase activity
KFV34_RS02025	COG3001	Fructosamine kinase
KFV34_RS02030	COG1113	amino acid transport
KFV34_RS02045	COG0741	lytic transglycosylase activity
KFV34_RS02055	COG3942	CHAP domain
KFV34_RS02060	COG0436	Aminotransferase
KFV34_RS02070	COG2608	mercury ion transmembrane transporter activity
KFV34_RS02075	COG2217	Heavy metal translocating P-type atpase
KFV34_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
KFV34_RS02090	COG1012	belongs to the aldehyde dehydrogenase family
KFV34_RS02115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KFV34_RS02120	COG3425	synthase
KFV34_RS02140	COG0583	DNA-binding transcription factor activity
KFV34_RS02145	COG1380	Effector of murein hydrolase LrgA
KFV34_RS02150	COG1346	cytolysis
KFV34_RS02155	COG0028	Belongs to the TPP enzyme family
KFV34_RS02160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KFV34_RS02160	COG1263	PTS System
KFV34_RS02160	COG2190	(PTS) system
KFV34_RS02175	COG1063	alcohol dehydrogenase
KFV34_RS02185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KFV34_RS02200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFV34_RS02210	COG2843	Capsule synthesis protein
KFV34_RS02225	COG4975	Glucose uptake
KFV34_RS02230	COG1869	D-ribose catabolic process
KFV34_RS02240	COG1070	Carbohydrate kinase
KFV34_RS02255	COG1760	l-serine dehydratase
KFV34_RS02260	COG1760	l-serine dehydratase
KFV34_RS02285	COG3764	Sortase (surface protein transpeptidase)
KFV34_RS02295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFV34_RS02300	COG0778	Nitroreductase
KFV34_RS02305	COG1012	belongs to the aldehyde dehydrogenase family
KFV34_RS02315	COG2514	catechol 2,3-dioxygenase activity
KFV34_RS02330	COG1012	belongs to the aldehyde dehydrogenase family
KFV34_RS02335	COG3949	Membrane
KFV34_RS02345	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
KFV34_RS02350	COG0586	Pfam SNARE associated Golgi protein
KFV34_RS02355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFV34_RS02360	COG2022	thiamine diphosphate biosynthetic process
KFV34_RS02370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFV34_RS02380	COG2271	Major facilitator Superfamily
KFV34_RS02395	COG4876	unkown
KFV34_RS02400	COG2357	RelA SpoT domain protein
KFV34_RS02415	COG0789	Transcriptional regulator
KFV34_RS02420	COG2271	Major facilitator Superfamily
KFV34_RS02425	COG1802	Transcriptional regulator
KFV34_RS02435	COG2610	gluconate transmembrane transporter activity
KFV34_RS02440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KFV34_RS02445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFV34_RS02450	COG0438	transferase activity, transferring glycosyl groups
KFV34_RS02455	COG0494	nUDIX hydrolase
KFV34_RS02460	COG0556	nucleotide-excision repair
KFV34_RS02475	COG4221	oxidoreductase activity
KFV34_RS02480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFV34_RS02485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFV34_RS02495	COG1028	Short-chain dehydrogenase reductase Sdr
KFV34_RS02505	COG1363	Peptidase, m42
KFV34_RS02515	COG0069	glutamate synthase activity
KFV34_RS02530	COG4619	ABC transporter
KFV34_RS02535	COG0390	transport system, permease component
KFV34_RS02540	COG2814	Major facilitator Superfamily
KFV34_RS02545	COG2272	Belongs to the type-B carboxylesterase lipase family
KFV34_RS02550	COG0531	amino acid
KFV34_RS02560	COG1063	alcohol dehydrogenase
KFV34_RS02580	COG1174	glycine betaine transport
KFV34_RS02585	COG1346	cytolysis
KFV34_RS02590	COG1380	Effector of murein hydrolase LrgA
KFV34_RS02595	COG3279	Response regulator of the LytR AlgR family
KFV34_RS02600	COG3275	phosphorelay sensor kinase activity
KFV34_RS02610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KFV34_RS02615	COG0706	membrane insertase activity
KFV34_RS02625	COG0531	amino acid
KFV34_RS02630	COG1113	amino acid transport
KFV34_RS02655	COG1929	Belongs to the glycerate kinase type-1 family
KFV34_RS02670	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KFV34_RS02675	COG0588	phosphoglycerate mutase activity
KFV34_RS02685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KFV34_RS02690	COG0765	amino acid transport
KFV34_RS02695	COG1126	abc transporter atp-binding protein
KFV34_RS02705	COG2348	transferase activity, transferring amino-acyl groups
KFV34_RS02725	COG2116	formate transmembrane transporter activity
KFV34_RS02730	COG0454	-acetyltransferase
KFV34_RS02740	COG0747	negative chemotaxis
KFV34_RS02750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFV34_RS02755	COG2146	nitrite reductase [NAD(P)H] activity
KFV34_RS02765	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KFV34_RS02770	COG1140	nitrate reductase beta subunit
KFV34_RS02780	COG2181	nitrate reductase activity
KFV34_RS02790	COG4585	Histidine kinase
KFV34_RS02795	COG2197	response regulator
KFV34_RS02800	COG2223	nitrite transmembrane transporter activity
KFV34_RS02805	COG1846	Transcriptional regulator
KFV34_RS02830	COG3871	stress protein (general stress protein 26)
KFV34_RS02845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KFV34_RS02845	COG1263	PTS System
KFV34_RS02880	COG0604	alcohol dehydrogenase
KFV34_RS02885	COG0456	acetyltransferase
KFV34_RS02890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV34_RS02890	COG0463	Glycosyl transferase, family 2
KFV34_RS02900	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV34_RS02900	COG0463	Glycosyl transferase, family 2
KFV34_RS02905	COG1620	l-lactate permease
KFV34_RS02910	COG0438	transferase activity, transferring glycosyl groups
KFV34_RS02915	COG0579	oxidoreductase
KFV34_RS02920	COG5002	protein histidine kinase activity
KFV34_RS02920	COG3850	Histidine kinase
KFV34_RS02925	COG0745	RESPONSE REGULATOR receiver
KFV34_RS02930	COG0577	efflux transmembrane transporter activity
KFV34_RS02935	COG1136	(ABC) transporter
KFV34_RS02950	COG4640	response to antibiotic
KFV34_RS02955	COG2814	Major facilitator Superfamily
KFV34_RS02965	COG1566	PFAM secretion protein HlyD family protein
KFV34_RS02970	COG2814	Major facilitator Superfamily
KFV34_RS02980	COG0657	acetylesterase activity
KFV34_RS02995	COG0598	Magnesium transport protein CorA
KFV34_RS03000	COG1304	FMN binding
KFV34_RS03005	COG0786	glutamate:sodium symporter activity
KFV34_RS03025	COG2094	Belongs to the DNA glycosylase MPG family
KFV34_RS03035	COG1069	ribulokinase activity
KFV34_RS03040	COG2017	converts alpha-aldose to the beta-anomer
KFV34_RS03045	COG2258	MOSC domain
KFV34_RS03050	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFV34_RS03060	COG1266	CAAX protease self-immunity
KFV34_RS03065	COG0010	Belongs to the arginase family
KFV34_RS03070	COG1473	amidohydrolase
KFV34_RS03075	COG1028	Short-chain dehydrogenase reductase Sdr
KFV34_RS03080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KFV34_RS03110	COG1737	Transcriptional regulator
KFV34_RS03115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KFV34_RS03115	COG1263	PTS System
KFV34_RS03125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFV34_RS03150	COG1113	amino acid transport
KFV34_RS03160	COG1263	PTS System
KFV34_RS03160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KFV34_RS03165	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KFV34_RS03180	COG1266	CAAX protease self-immunity
KFV34_RS03185	COG2378	regulation of single-species biofilm formation
KFV34_RS03190	COG0483	inositol monophosphate 1-phosphatase activity
KFV34_RS03195	COG1316	TRANSCRIPTIONal
KFV34_RS03215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFV34_RS03220	COG2076	Multidrug Resistance protein
KFV34_RS03225	COG2076	Multidrug Resistance protein
KFV34_RS03230	COG3942	CHAP domain
KFV34_RS03245	COG1757	Na H antiporter
KFV34_RS03250	COG3942	CHAP domain
KFV34_RS03275	COG0829	nickel cation binding
KFV34_RS03280	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KFV34_RS03285	COG0830	nickel cation binding
KFV34_RS03290	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KFV34_RS03295	COG0804	urea catabolic process
KFV34_RS03300	COG0832	Belongs to the urease beta subunit family
KFV34_RS03305	COG0831	urea catabolic process
KFV34_RS03315	COG1960	acyl-CoA dehydrogenase activity
KFV34_RS03325	COG1268	BioY protein
KFV34_RS03340	COG0725	ABC transporter, periplasmic molybdate-binding protein
KFV34_RS03345	COG4149	molybdate abc transporter
KFV34_RS03350	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KFV34_RS03355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFV34_RS03360	COG0521	Mo-molybdopterin cofactor biosynthetic process
KFV34_RS03365	COG0315	cyclic pyranopterin monophosphate synthase activity
KFV34_RS03370	COG0303	'Molybdopterin
KFV34_RS03380	COG0314	molybdopterin synthase activity
KFV34_RS03390	COG0746	molybdenum cofactor guanylyltransferase activity
KFV34_RS03395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFV34_RS03415	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFV34_RS03420	COG0561	phosphatase activity
KFV34_RS03435	COG0542	response to heat
KFV34_RS03450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFV34_RS03465	COG0601	transmembrane transport
KFV34_RS03470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFV34_RS03475	COG0444	Belongs to the ABC transporter superfamily
KFV34_RS03480	COG4608	Belongs to the ABC transporter superfamily
KFV34_RS03485	COG4166	transmembrane transport
KFV34_RS03490	COG0180	Tryptophanyl-tRNA synthetase
KFV34_RS03495	COG1393	Belongs to the ArsC family
KFV34_RS03505	COG4862	establishment of competence for transformation
KFV34_RS03515	COG1164	Oligoendopeptidase f
KFV34_RS03520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KFV34_RS03525	COG2346	COG2346, Truncated hemoglobins
KFV34_RS03540	COG2357	RelA SpoT domain protein
KFV34_RS03545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KFV34_RS03550	COG0564	pseudouridine synthase activity
KFV34_RS03555	COG2239	Acts as a magnesium transporter
KFV34_RS03560	COG0475	glutathione-regulated potassium exporter activity
KFV34_RS03560	COG0569	domain protein
KFV34_RS03615	COG0628	permease
KFV34_RS03620	COG2382	esterase
KFV34_RS03625	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KFV34_RS03630	COG2814	Major facilitator Superfamily
KFV34_RS03635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KFV34_RS03640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFV34_RS03650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFV34_RS03655	COG0861	Integral membrane protein TerC family
KFV34_RS03660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFV34_RS03665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFV34_RS03680	COG4873	Protein conserved in bacteria
KFV34_RS03740	COG2314	TM2 domain
KFV34_RS03745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KFV34_RS03750	COG1575	Belongs to the MenA family. Type 1 subfamily
KFV34_RS03755	COG1169	isochorismate synthase
KFV34_RS03760	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KFV34_RS03770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KFV34_RS03775	COG0436	Aminotransferase
KFV34_RS03780	COG3594	Acyltransferase
KFV34_RS03805	COG1316	TRANSCRIPTIONal
KFV34_RS03820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KFV34_RS03825	COG1845	cytochrome c oxidase, subunit III
KFV34_RS03830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFV34_RS03835	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KFV34_RS03845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFV34_RS03850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KFV34_RS03855	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KFV34_RS03860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KFV34_RS03865	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFV34_RS03870	COG0047	phosphoribosylformylglycinamidine synthase activity
KFV34_RS03875	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFV34_RS03880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KFV34_RS03885	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KFV34_RS03890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFV34_RS03895	COG0138	bifunctional purine biosynthesis protein purh
KFV34_RS03900	COG0151	Belongs to the GarS family
KFV34_RS03905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KFV34_RS03910	COG4172	Belongs to the ABC transporter superfamily
KFV34_RS03920	COG4716	Myosin-crossreactive antigen
KFV34_RS03945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFV34_RS03950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFV34_RS03960	COG1271	oxidase subunit
KFV34_RS03965	COG1294	oxidase, subunit
KFV34_RS03970	COG0569	domain protein
KFV34_RS03975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KFV34_RS03980	COG5503	Protein of unknown function (DUF1447)
KFV34_RS03985	COG0242	peptide deformylase activity
KFV34_RS03995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFV34_RS04000	COG0022	dehydrogenase e1 component
KFV34_RS04005	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFV34_RS04015	COG4476	Belongs to the UPF0223 family
KFV34_RS04025	COG3842	ATPase activity
KFV34_RS04030	COG1176	ABC-type spermidine putrescine transport system, permease component I
KFV34_RS04055	COG1914	H( )-stimulated, divalent metal cation uptake system
KFV34_RS04060	COG4493	Belongs to the UPF0637 family
KFV34_RS04065	COG0483	inositol monophosphate 1-phosphatase activity
KFV34_RS04075	COG1217	gtp-binding protein TYPA
KFV34_RS04090	COG4896	Protein conserved in bacteria
KFV34_RS04095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KFV34_RS04100	COG4838	Belongs to the UPF0358 family
KFV34_RS04105	COG0772	Belongs to the SEDS family
KFV34_RS04115	COG1612	heme a metabolic process
KFV34_RS04120	COG0109	protoheme IX farnesyltransferase activity
KFV34_RS04130	COG2340	Cysteine-rich secretory protein family
KFV34_RS04135	COG3679	Belongs to the UPF0342 family
KFV34_RS04140	COG0584	glycerophosphoryl diester phosphodiesterase
KFV34_RS04145	COG4471	UPF0298 protein
KFV34_RS04155	COG0742	ribosomal rna small subunit methyltransferase
KFV34_RS04160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KFV34_RS04165	COG1323	Belongs to the UPF0348 family
KFV34_RS04175	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KFV34_RS04185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFV34_RS04190	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFV34_RS04195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFV34_RS04195	COG0072	phenylalanine-tRNA ligase activity
KFV34_RS04200	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFV34_RS04205	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KFV34_RS04215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KFV34_RS04215	COG1796	DNA polymerase
KFV34_RS04220	COG1193	negative regulation of DNA recombination
KFV34_RS04225	COG3118	belongs to the thioredoxin family
KFV34_RS04230	COG0322	excinuclease ABC activity
KFV34_RS04235	COG2009	succinate dehydrogenase
KFV34_RS04240	COG1053	succinate dehydrogenase
KFV34_RS04245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KFV34_RS04250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KFV34_RS04255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFV34_RS04285	COG1011	Hydrolase
KFV34_RS04290	COG0454	-acetyltransferase
KFV34_RS04295	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KFV34_RS04300	COG2001	Belongs to the MraZ family
KFV34_RS04305	COG0275	rRNA processing
KFV34_RS04310	COG4839	cell division protein FtsL
KFV34_RS04315	COG0768	penicillin binding
KFV34_RS04320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFV34_RS04325	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFV34_RS04330	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFV34_RS04335	COG0849	cell division
KFV34_RS04340	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KFV34_RS04345	COG1496	oxidoreductase activity
KFV34_RS04350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KFV34_RS04355	COG1799	cell septum assembly
KFV34_RS04360	COG0762	integral membrane protein
KFV34_RS04370	COG3599	regulation of cell shape
KFV34_RS04375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KFV34_RS04385	COG1388	LysM domain
KFV34_RS04385	COG3942	CHAP domain
KFV34_RS04390	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KFV34_RS04395	COG0564	pseudouridine synthase activity
KFV34_RS04400	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KFV34_RS04405	COG2233	PERMEase
KFV34_RS04410	COG0540	Belongs to the ATCase OTCase family
KFV34_RS04415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFV34_RS04420	COG0505	Belongs to the CarA family
KFV34_RS04425	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFV34_RS04430	COG0284	orotidine-5'-phosphate decarboxylase activity
KFV34_RS04435	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFV34_RS04455	COG0194	GDP metabolic process
KFV34_RS04460	COG1758	RNA polymerase activity
KFV34_RS04465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFV34_RS04470	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFV34_RS04480	COG0242	peptide deformylase activity
KFV34_RS04485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFV34_RS04490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KFV34_RS04490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFV34_RS04495	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFV34_RS04500	COG0631	protein serine/threonine phosphatase activity
KFV34_RS04510	COG1162	GTPase activity
KFV34_RS04515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KFV34_RS04525	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KFV34_RS04530	COG1302	Protein conserved in bacteria
KFV34_RS04535	COG1461	Dihydroxyacetone kinase
KFV34_RS04540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFV34_RS04545	COG1349	DNA-binding transcription factor activity
KFV34_RS04550	COG0416	fatty acid biosynthetic process
KFV34_RS04560	COG1028	Short-chain dehydrogenase reductase Sdr
KFV34_RS04565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFV34_RS04570	COG0571	ribonuclease III activity
KFV34_RS04575	COG1196	nuclear chromosome segregation
KFV34_RS04580	COG0552	protein localization to endoplasmic reticulum
KFV34_RS04585	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KFV34_RS04590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFV34_RS04595	COG0228	four-way junction DNA binding
KFV34_RS04600	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFV34_RS04605	COG0336	Belongs to the RNA methyltransferase TrmD family
KFV34_RS04610	COG0335	large ribosomal subunit rRNA binding
KFV34_RS04620	COG4485	Bacterial membrane protein, YfhO
KFV34_RS04630	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFV34_RS04635	COG0045	succinate-CoA ligase (ADP-forming) activity
KFV34_RS04640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KFV34_RS04645	COG0758	DNA mediated transformation
KFV34_RS04650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFV34_RS04655	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KFV34_RS04660	COG4974	Belongs to the 'phage' integrase family
KFV34_RS04665	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KFV34_RS04670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KFV34_RS04675	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KFV34_RS04680	COG0052	Belongs to the universal ribosomal protein uS2 family
KFV34_RS04685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFV34_RS04690	COG0528	UMP kinase activity
KFV34_RS04695	COG0233	cytoplasmic translational termination
KFV34_RS04700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KFV34_RS04705	COG4589	Belongs to the CDS family
KFV34_RS04715	COG0442	prolyl-tRNA aminoacylation
KFV34_RS04720	COG2176	DNA-directed DNA polymerase activity
KFV34_RS04725	COG0779	Required for maturation of 30S ribosomal subunits
KFV34_RS04730	COG0195	Participates in both transcription termination and antitermination
KFV34_RS04735	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KFV34_RS04740	COG1358	cellular component organization or biogenesis
KFV34_RS04745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KFV34_RS04750	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KFV34_RS04755	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KFV34_RS04760	COG0196	riboflavin kinase activity
KFV34_RS04765	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KFV34_RS04770	COG1185	polyribonucleotide nucleotidyltransferase activity
KFV34_RS04775	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KFV34_RS04780	COG1674	ftsk spoiiie
KFV34_RS04785	COG2188	Transcriptional regulator
KFV34_RS04790	COG0612	Peptidase, M16
KFV34_RS04795	COG0612	Peptidase, M16
KFV34_RS04800	COG0300	oxidoreductase activity
KFV34_RS04815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFV34_RS04825	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFV34_RS04830	COG1418	mRNA catabolic process
KFV34_RS04840	COG1692	metallophosphoesterase
KFV34_RS04845	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KFV34_RS04845	COG0674	pyruvate-flavodoxin oxidoreductase activity
KFV34_RS04850	COG1013	pyruvate-flavodoxin oxidoreductase activity
KFV34_RS04855	COG4195	phage-related replication protein
KFV34_RS04865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFV34_RS04870	COG4550	Control of competence regulator ComK, YlbF/YmcA
KFV34_RS04880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFV34_RS04885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFV34_RS04890	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KFV34_RS04895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KFV34_RS04900	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KFV34_RS04905	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KFV34_RS04915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFV34_RS04920	COG1923	regulation of RNA biosynthetic process
KFV34_RS04925	COG0386	Belongs to the glutathione peroxidase family
KFV34_RS04930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFV34_RS04935	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KFV34_RS04940	COG0789	Transcriptional regulator
KFV34_RS04945	COG0174	glutamine synthetase
KFV34_RS05005	COG0629	single-stranded DNA binding
KFV34_RS05030	COG1595	DNA-templated transcription, initiation
KFV34_RS05150	COG4824	toxin secretion phage lysis holin
KFV34_RS05210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFV34_RS05215	COG1131	(ABC) transporter
KFV34_RS05225	COG4585	Histidine kinase
KFV34_RS05230	COG2197	response regulator
KFV34_RS05240	COG1525	nuclease
KFV34_RS05255	COG0527	aspartate kinase activity
KFV34_RS05260	COG0460	homoserine dehydrogenase
KFV34_RS05265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFV34_RS05270	COG0083	homoserine kinase activity
KFV34_RS05285	COG0833	amino acid
KFV34_RS05290	COG0753	catalase activity
KFV34_RS05300	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFV34_RS05305	COG0516	GMP reductase activity
KFV34_RS05310	COG2340	Cysteine-rich secretory protein family
KFV34_RS05315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFV34_RS05325	COG4224	UPF0291 protein
KFV34_RS05330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFV34_RS05340	COG4846	Membrane protein involved in cytochrome C biogenesis
KFV34_RS05345	COG0420	3'-5' exonuclease activity
KFV34_RS05350	COG0419	ATPase involved in DNA repair
KFV34_RS05355	COG1970	mechanosensitive ion channel activity
KFV34_RS05360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KFV34_RS05365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KFV34_RS05370	COG0824	Thioesterase
KFV34_RS05380	COG4841	protein insertion into membrane
KFV34_RS05385	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KFV34_RS05390	COG0187	DNA topoisomerase II activity
KFV34_RS05395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KFV34_RS05400	COG1115	amino acid carrier protein
KFV34_RS05405	COG3711	transcriptional antiterminator
KFV34_RS05410	COG0628	permease
KFV34_RS05415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KFV34_RS05415	COG0392	lysyltransferase activity
KFV34_RS05430	COG1942	4-Oxalocrotonate Tautomerase
KFV34_RS05435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFV34_RS05440	COG0287	Prephenate dehydrogenase
KFV34_RS05445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFV34_RS05450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFV34_RS05450	COG0512	Glutamine amidotransferase of anthranilate synthase
KFV34_RS05455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFV34_RS05460	COG0134	indole-3-glycerol-phosphate synthase activity
KFV34_RS05465	COG0135	phosphoribosylanthranilate isomerase activity
KFV34_RS05470	COG0133	tryptophan synthase activity
KFV34_RS05475	COG0159	tryptophan synthase activity
KFV34_RS05485	COG2348	transferase activity, transferring amino-acyl groups
KFV34_RS05490	COG2348	transferase activity, transferring amino-acyl groups
KFV34_RS05500	COG4607	ABC-type enterochelin transport system periplasmic component
KFV34_RS05535	COG0704	Plays a role in the regulation of phosphate uptake
KFV34_RS05540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KFV34_RS05545	COG0581	inorganic phosphate transmembrane transporter activity
KFV34_RS05550	COG0573	inorganic phosphate transmembrane transporter activity
KFV34_RS05555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFV34_RS05560	COG2996	Protein conserved in bacteria
KFV34_RS05565	COG0488	(ABC) transporter
KFV34_RS05570	COG0527	aspartate kinase activity
KFV34_RS05575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KFV34_RS05580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFV34_RS05585	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KFV34_RS05590	COG2171	N-acyltransferase activity
KFV34_RS05595	COG1473	amidohydrolase
KFV34_RS05615	COG1131	(ABC) transporter
KFV34_RS05630	COG1278	Cold shock
KFV34_RS05640	COG1254	Belongs to the acylphosphatase family
KFV34_RS05650	COG3853	Toxic anion resistance protein (TelA)
KFV34_RS05655	COG1114	Component of the transport system for branched-chain amino acids
KFV34_RS05660	COG4548	von Willebrand factor, type A
KFV34_RS05665	COG0714	Associated with various cellular activities
KFV34_RS05690	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFV34_RS05695	COG0567	Dehydrogenase, E1 component
KFV34_RS05700	COG5002	protein histidine kinase activity
KFV34_RS05705	COG0745	RESPONSE REGULATOR receiver
KFV34_RS05710	COG1349	DNA-binding transcription factor activity
KFV34_RS05715	COG0534	Mate efflux family protein
KFV34_RS05725	COG0395	ABC-type sugar transport system, permease component
KFV34_RS05735	COG4209	transmembrane transport
KFV34_RS05740	COG3842	ATPase activity
KFV34_RS05745	COG0671	phosphoesterase, PA-phosphatase related
KFV34_RS05750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KFV34_RS05760	COG0793	Belongs to the peptidase S41A family
KFV34_RS05765	COG4479	Belongs to the UPF0346 family
KFV34_RS05770	COG2190	(PTS) system
KFV34_RS05775	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFV34_RS05800	COG1136	(ABC) transporter
KFV34_RS05815	COG1413	lyase activity
KFV34_RS05825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KFV34_RS05840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFV34_RS05845	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KFV34_RS05855	COG0116	Belongs to the methyltransferase superfamily
KFV34_RS05865	COG3599	regulation of cell shape
KFV34_RS05870	COG4474	Belongs to the UPF0398 family
KFV34_RS05880	COG3331	DNA recombination
KFV34_RS05885	COG4499	WXG100 protein secretion system (Wss), protein YukC
KFV34_RS05885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFV34_RS05895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFV34_RS05900	COG3935	DnaD domain protein
KFV34_RS05905	COG0017	Asparaginyl-tRNA synthetase
KFV34_RS05910	COG1199	ATP-dependent helicase activity
KFV34_RS05910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFV34_RS05915	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFV34_RS05915	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFV34_RS05920	COG0617	tRNA 3'-terminal CCA addition
KFV34_RS05925	COG0438	transferase activity, transferring glycosyl groups
KFV34_RS05930	COG1694	Mazg nucleotide pyrophosphohydrolase
KFV34_RS05935	COG2738	Putative neutral zinc metallopeptidase
KFV34_RS05940	COG4347	Protein of unknown function (DUF1405)
KFV34_RS05945	COG5582	Belongs to the UPF0302 family
KFV34_RS05955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KFV34_RS05960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KFV34_RS05965	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KFV34_RS05970	COG0105	UTP biosynthetic process
KFV34_RS05980	COG2226	methyltransferase
KFV34_RS05995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFV34_RS06000	COG1160	GTP binding
KFV34_RS06005	COG0539	negative regulation of cytoplasmic translation
KFV34_RS06010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFV34_RS06015	COG0252	asparaginase activity
KFV34_RS06020	COG0492	ferredoxin-NADP+ reductase activity
KFV34_RS06025	COG1388	LysM domain
KFV34_RS06030	COG0514	ATP-dependent DNA helicase (RecQ)
KFV34_RS06040	COG1141	Ferredoxin
KFV34_RS06055	COG0745	RESPONSE REGULATOR receiver
KFV34_RS06060	COG1187	pseudouridine synthase activity
KFV34_RS06065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFV34_RS06070	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFV34_RS06075	COG1547	Domain of unknown function (DUF309)
KFV34_RS06080	COG4974	Belongs to the 'phage' integrase family
KFV34_RS06085	COG0735	belongs to the Fur family
KFV34_RS06090	COG0494	nUDIX hydrolase
KFV34_RS06095	COG0667	Aldo Keto reductase
KFV34_RS06100	COG1028	Short-chain dehydrogenase reductase Sdr
KFV34_RS06105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KFV34_RS06110	COG1234	tRNA 3'-trailer cleavage
KFV34_RS06115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFV34_RS06125	COG0366	Alpha amylase catalytic
KFV34_RS06130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KFV34_RS06135	COG2195	Cleaves the N-terminal amino acid of tripeptides
KFV34_RS06145	COG4129	membrane
KFV34_RS06155	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFV34_RS06160	COG0022	dehydrogenase e1 component
KFV34_RS06165	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFV34_RS06170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFV34_RS06175	COG0497	DNA recombination
KFV34_RS06180	COG1438	arginine binding
KFV34_RS06190	COG1722	exodeoxyribonuclease VII activity
KFV34_RS06195	COG1570	exodeoxyribonuclease VII activity
KFV34_RS06200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFV34_RS06205	COG1302	Protein conserved in bacteria
KFV34_RS06210	COG0439	Biotin carboxylase
KFV34_RS06215	COG0511	ligase activity, forming carbon-carbon bonds
KFV34_RS06220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFV34_RS06225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFV34_RS06230	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KFV34_RS06235	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KFV34_RS06240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFV34_RS06245	COG0006	proline dipeptidase activity
KFV34_RS06260	COG0095	Lipoate-protein ligase
KFV34_RS06265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFV34_RS06275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFV34_RS06280	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFV34_RS06285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KFV34_RS06290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KFV34_RS06310	COG4537	Required for transformation and DNA binding
KFV34_RS06315	COG1459	type II secretion system
KFV34_RS06320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFV34_RS06330	COG0011	TIGRFAM Protein of
KFV34_RS06335	COG1940	carbohydrate kinase activity
KFV34_RS06340	COG4483	Protein conserved in bacteria
KFV34_RS06350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFV34_RS06355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KFV34_RS06360	COG0768	penicillin binding
KFV34_RS06365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFV34_RS06370	COG0735	belongs to the Fur family
KFV34_RS06375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KFV34_RS06380	COG1121	(ABC) transporter
KFV34_RS06385	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KFV34_RS06390	COG0513	Belongs to the DEAD box helicase family
KFV34_RS06395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KFV34_RS06400	COG2384	SAM-dependent methyltransferase
KFV34_RS06405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFV34_RS06410	COG0358	DNA primase activity
KFV34_RS06415	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFV34_RS06420	COG0517	IMP dehydrogenase activity
KFV34_RS06425	COG0423	glycine-tRNA ligase activity
KFV34_RS06430	COG1381	Involved in DNA repair and RecF pathway recombination
KFV34_RS06435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KFV34_RS06440	COG0295	cytidine deaminase activity
KFV34_RS06445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KFV34_RS06450	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KFV34_RS06455	COG1702	phosphate starvation-inducible protein PhoH
KFV34_RS06465	COG4864	UPF0365 protein
KFV34_RS06470	COG1030	water channel activity
KFV34_RS06480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFV34_RS06485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFV34_RS06490	COG2264	protein methyltransferase activity
KFV34_RS06495	COG0484	heat shock protein binding
KFV34_RS06500	COG0443	Heat shock 70 kDa protein
KFV34_RS06505	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFV34_RS06510	COG1420	regulation of RNA biosynthetic process
KFV34_RS06515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFV34_RS06520	COG0481	GTPase activity
KFV34_RS06525	COG0268	Binds directly to 16S ribosomal RNA
KFV34_RS06530	COG1466	dna polymerase III delta subunit
KFV34_RS06535	COG2333	competence protein COMEC
KFV34_RS06535	COG0658	competence protein
KFV34_RS06540	COG2131	deaminase
KFV34_RS06550	COG2226	methyltransferase
KFV34_RS06555	COG0799	negative regulation of ribosome biogenesis
KFV34_RS06560	COG1713	HD superfamily hydrolase involved in NAD metabolism
KFV34_RS06565	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFV34_RS06570	COG1534	Rna-binding protein
KFV34_RS06575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KFV34_RS06580	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KFV34_RS06585	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KFV34_RS06590	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KFV34_RS06595	COG1914	H( )-stimulated, divalent metal cation uptake system
KFV34_RS06600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KFV34_RS06605	COG0439	Biotin carboxylase
KFV34_RS06610	COG0511	ligase activity, forming carbon-carbon bonds
KFV34_RS06615	COG1984	allophanate hydrolase subunit 2
KFV34_RS06620	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KFV34_RS06630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFV34_RS06635	COG0572	uridine kinase
KFV34_RS06640	COG0826	peptidase U32
KFV34_RS06645	COG0826	peptidase U32
KFV34_RS06655	COG3906	Belongs to the UPF0473 family
KFV34_RS06660	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFV34_RS06665	COG4472	Bacterial protein of unknown function (DUF965)
KFV34_RS06670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KFV34_RS06675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFV34_RS06685	COG0482	sulfurtransferase activity
KFV34_RS06690	COG1104	cysteine desulfurase activity
KFV34_RS06695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFV34_RS06705	COG1959	2 iron, 2 sulfur cluster binding
KFV34_RS06710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFV34_RS06715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KFV34_RS06725	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KFV34_RS06730	COG0124	histidyl-tRNA synthetase
KFV34_RS06735	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFV34_RS06740	COG1490	D-aminoacyl-tRNA deacylase activity
KFV34_RS06745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFV34_RS06750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KFV34_RS06755	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KFV34_RS06755	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KFV34_RS06760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFV34_RS06760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFV34_RS06765	COG1862	Preprotein translocase
KFV34_RS06770	COG0343	queuine tRNA-ribosyltransferase activity
KFV34_RS06775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFV34_RS06780	COG2255	four-way junction helicase activity
KFV34_RS06785	COG0632	four-way junction helicase activity
KFV34_RS06790	COG4492	Belongs to the UPF0735 family
KFV34_RS06795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFV34_RS06800	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KFV34_RS06805	COG2868	ribosomal protein
KFV34_RS06810	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KFV34_RS06820	COG1792	Involved in formation and maintenance of cell shape
KFV34_RS06840	COG2003	Belongs to the UPF0758 family
KFV34_RS06850	COG0285	dihydrofolate synthase activity
KFV34_RS06855	COG0525	valine-tRNA ligase activity
KFV34_RS06860	COG2818	Glycosylase
KFV34_RS06870	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFV34_RS06875	COG0113	porphobilinogen synthase activity
KFV34_RS06885	COG0181	hydroxymethylbilane synthase activity
KFV34_RS06895	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFV34_RS06900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KFV34_RS06905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFV34_RS06910	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFV34_RS06920	COG4112	unkown
KFV34_RS06925	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFV34_RS06930	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KFV34_RS06935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFV34_RS06940	COG0833	amino acid
KFV34_RS06945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KFV34_RS06950	COG1484	DNA-dependent DNA replication
KFV34_RS06955	COG3611	Membrane attachment protein
KFV34_RS06960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFV34_RS06965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFV34_RS06975	COG0237	dephospho-CoA kinase activity
KFV34_RS06980	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFV34_RS06985	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFV34_RS06985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFV34_RS06990	COG5002	protein histidine kinase activity
KFV34_RS06995	COG0745	RESPONSE REGULATOR receiver
KFV34_RS07000	COG0538	isocitrate dehydrogenase activity
KFV34_RS07005	COG0372	Belongs to the citrate synthase family
KFV34_RS07010	COG1113	amino acid transport
KFV34_RS07015	COG0469	pyruvate kinase activity
KFV34_RS07020	COG0205	6-phosphofructokinase activity
KFV34_RS07025	COG0825	malonyl-CoA metabolic process
KFV34_RS07030	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFV34_RS07035	COG0281	malic enzyme
KFV34_RS07040	COG0587	DNA-directed DNA polymerase activity
KFV34_RS07045	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KFV34_RS07050	COG4109	DRTGG domain
KFV34_RS07060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KFV34_RS07065	COG0006	proline dipeptidase activity
KFV34_RS07070	COG0686	Belongs to the AlaDH PNT family
KFV34_RS07075	COG0589	response to stress
KFV34_RS07085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KFV34_RS07090	COG0827	DNA restriction-modification system
KFV34_RS07095	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KFV34_RS07105	COG0301	tRNA thio-modification
KFV34_RS07115	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KFV34_RS07120	COG1956	GAF domain-containing protein
KFV34_RS07125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KFV34_RS07130	COG0584	glycerophosphoryl diester phosphodiesterase
KFV34_RS07135	COG1764	response to oxidative stress
KFV34_RS07140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KFV34_RS07145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFV34_RS07155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KFV34_RS07155	COG1263	PTS System
KFV34_RS07160	COG0204	Acyl-transferase
KFV34_RS07165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFV34_RS07170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFV34_RS07180	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KFV34_RS07185	COG1609	Transcriptional regulator
KFV34_RS07190	COG1605	Chorismate mutase
KFV34_RS07190	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KFV34_RS07200	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KFV34_RS07205	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFV34_RS07210	COG1674	ftsk spoiiie
KFV34_RS07215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFV34_RS07220	COG4848	Belongs to the UPF0354 family
KFV34_RS07225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFV34_RS07230	COG1363	Peptidase, m42
KFV34_RS07240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KFV34_RS07245	COG0510	thiamine kinase activity
KFV34_RS07250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFV34_RS07255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFV34_RS07265	COG1187	pseudouridine synthase activity
KFV34_RS07270	COG2244	polysaccharide biosynthetic process
KFV34_RS07275	COG2081	HI0933 family
KFV34_RS07290	COG0495	leucyl-tRNA aminoacylation
KFV34_RS07295	COG2814	Major facilitator Superfamily
KFV34_RS07300	COG1242	4 iron, 4 sulfur cluster binding
KFV34_RS07305	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KFV34_RS07320	COG2267	carboxylic ester hydrolase activity
KFV34_RS07325	COG0506	proline dehydrogenase activity
KFV34_RS07330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFV34_RS07335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFV34_RS07335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFV34_RS07345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFV34_RS07345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFV34_RS07355	COG3266	domain, Protein
KFV34_RS07355	COG5632	N-Acetylmuramoyl-L-alanine amidase
KFV34_RS07355	COG4193	domain, Protein
KFV34_RS07380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFV34_RS07390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFV34_RS07395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFV34_RS07410	COG0656	L-ascorbic acid biosynthetic process
KFV34_RS07420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFV34_RS07425	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KFV34_RS07430	COG1506	peptidase
KFV34_RS07435	COG0494	nUDIX hydrolase
KFV34_RS07440	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KFV34_RS07450	COG0318	PFAM AMP-dependent synthetase and ligase
KFV34_RS07555	COG3942	CHAP domain
KFV34_RS07710	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KFV34_RS07715	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFV34_RS07720	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFV34_RS07725	COG2329	Antibiotic biosynthesis monooxygenase
KFV34_RS07735	COG4473	ABC transporter
KFV34_RS07740	COG1131	(ABC) transporter
KFV34_RS07745	COG0537	adenosine 5'-monophosphoramidase activity
KFV34_RS07760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFV34_RS07770	COG3481	metal-dependent phosphohydrolase, HD sub domain
KFV34_RS07780	COG0420	3'-5' exonuclease activity
KFV34_RS07785	COG3679	Belongs to the UPF0342 family
KFV34_RS07790	COG4399	Belongs to the UPF0754 family
KFV34_RS07800	COG2197	response regulator
KFV34_RS07805	COG4585	Histidine kinase
KFV34_RS07805	COG2203	Gaf domain
KFV34_RS07815	COG0114	fumarate hydratase activity
KFV34_RS07840	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFV34_RS07850	COG1126	abc transporter atp-binding protein
KFV34_RS07855	COG0765	amino acid transport
KFV34_RS07885	COG4824	toxin secretion phage lysis holin
KFV34_RS07985	COG1595	DNA-templated transcription, initiation
KFV34_RS08255	COG0735	belongs to the Fur family
KFV34_RS08260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFV34_RS08265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFV34_RS08270	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFV34_RS08275	COG4129	membrane
KFV34_RS08285	COG3557	Belongs to the UPF0374 family
KFV34_RS08300	COG1988	membrane-bound metal-dependent
KFV34_RS08310	COG1388	LysM domain
KFV34_RS08310	COG1134	teichoic acid transport
KFV34_RS08320	COG2137	regulation of response to DNA damage stimulus
KFV34_RS08325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFV34_RS08330	COG0693	protein deglycase activity
KFV34_RS08340	COG0535	radical SAM domain protein
KFV34_RS08345	COG1607	acyl-coa hydrolase
KFV34_RS08350	COG2309	aminopeptidase activity
KFV34_RS08355	COG4840	Belongs to the UPF0435 family
KFV34_RS08360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFV34_RS08370	COG1295	ribonuclease BN
KFV34_RS08375	COG2197	response regulator
KFV34_RS08380	COG4585	Histidine kinase
KFV34_RS08395	COG0024	Methionine aminopeptidase
KFV34_RS08400	COG4129	membrane
KFV34_RS08420	COG1528	Iron-storage protein
KFV34_RS08430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFV34_RS08440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KFV34_RS08445	COG1597	lipid kinase activity
KFV34_RS08450	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFV34_RS08455	COG0154	amidase activity
KFV34_RS08460	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFV34_RS08465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFV34_RS08470	COG4851	CamS sex pheromone cAM373 precursor
KFV34_RS08475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFV34_RS08480	COG0210	DNA helicase
KFV34_RS08485	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KFV34_RS08490	COG4496	protein, YerC YecD
KFV34_RS08495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KFV34_RS08505	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KFV34_RS08510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFV34_RS08515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KFV34_RS08525	COG0077	Prephenate dehydratase
KFV34_RS08535	COG1335	isochorismatase
KFV34_RS08540	COG1227	inorganic diphosphatase activity
KFV34_RS08545	COG1012	belongs to the aldehyde dehydrogenase family
KFV34_RS08550	COG2706	6-phosphogluconolactonase activity
KFV34_RS08555	COG3682	Transcriptional regulator
KFV34_RS08585	COG4974	Belongs to the 'phage' integrase family
KFV34_RS08635	COG1131	(ABC) transporter
KFV34_RS08645	COG1131	(ABC) transporter
KFV34_RS08650	COG1725	Transcriptional regulator
KFV34_RS08775	COG3617	BRO family, N-terminal domain
KFV34_RS08790	COG0582	viral genome integration into host DNA
KFV34_RS08795	COG0459	protein refolding
KFV34_RS08800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KFV34_RS08840	COG3279	Response regulator of the LytR AlgR family
KFV34_RS08845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFV34_RS08850	COG1621	beta-fructofuranosidase activity
KFV34_RS08855	COG1609	Transcriptional regulator
KFV34_RS08860	COG0004	ammonium transporteR
KFV34_RS08865	COG0425	Belongs to the sulfur carrier protein TusA family
KFV34_RS08875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFV34_RS08915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFV34_RS08940	COG1780	Probably involved in ribonucleotide reductase function
KFV34_RS08980	COG0270	DNA (cytosine-5-)-methyltransferase activity
KFV34_RS08985	COG2226	methyltransferase
KFV34_RS09050	COG0587	DNA-directed DNA polymerase activity
KFV34_RS09055	COG0587	DNA-directed DNA polymerase activity
KFV34_RS09085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KFV34_RS09130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFV34_RS09265	COG0456	acetyltransferase
KFV34_RS09315	COG2887	Belongs to the helicase family. UvrD subfamily
KFV34_RS09415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFV34_RS09425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFV34_RS09455	COG4373	Mu-like prophage FluMu protein gp28
KFV34_RS09525	COG0582	viral genome integration into host DNA
KFV34_RS09540	COG2433	Pfam Transposase IS66
KFV34_RS09580	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFV34_RS09580	COG1388	LysM domain
KFV34_RS09620	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KFV34_RS09625	COG0488	(ABC) transporter
KFV34_RS09630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFV34_RS09635	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KFV34_RS09640	COG0456	acetyltransferase
KFV34_RS09645	COG1214	PFAM Peptidase M22, glycoprotease
KFV34_RS09650	COG0802	atpase or kinase
KFV34_RS09655	COG0129	dihydroxy-acid dehydratase activity
KFV34_RS09660	COG0028	Belongs to the TPP enzyme family
KFV34_RS09670	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFV34_RS09675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFV34_RS09680	COG0473	3-isopropylmalate dehydrogenase activity
KFV34_RS09685	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFV34_RS09690	COG0066	3-isopropylmalate dehydratase activity
KFV34_RS09695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFV34_RS09725	COG3091	SprT-like family
KFV34_RS09730	COG2183	response to ionizing radiation
KFV34_RS09735	COG1191	sigma factor activity
KFV34_RS09750	COG2208	phosphoserine phosphatase activity
KFV34_RS09755	COG2337	Toxic component of a toxin-antitoxin (TA) module
KFV34_RS09765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KFV34_RS09770	COG0736	holo-[acyl-carrier-protein] synthase activity
KFV34_RS09775	COG3402	PFAM membrane-flanked domain
KFV34_RS09780	COG3428	Bacterial PH domain
KFV34_RS09790	COG0513	Belongs to the DEAD box helicase family
KFV34_RS09795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFV34_RS09800	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFV34_RS09805	COG0772	Belongs to the SEDS family
KFV34_RS09820	COG1937	Protein conserved in bacteria
KFV34_RS09825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFV34_RS09830	COG1418	mRNA catabolic process
KFV34_RS09835	COG0706	membrane insertase activity
KFV34_RS09840	COG0352	thiamine-phosphate diphosphorylase activity
KFV34_RS09845	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KFV34_RS09855	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KFV34_RS09860	COG1388	LysM domain
KFV34_RS09865	COG0629	single-stranded DNA binding
KFV34_RS09875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFV34_RS09880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFV34_RS09890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFV34_RS09895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KFV34_RS09900	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KFV34_RS09905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFV34_RS09910	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFV34_RS09915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFV34_RS09925	COG0356	it plays a direct role in the translocation of protons across the membrane
KFV34_RS09935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KFV34_RS09940	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KFV34_RS09945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KFV34_RS09950	COG4475	Protein of unknown function (DUF436)
KFV34_RS09955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFV34_RS09960	COG0009	L-threonylcarbamoyladenylate synthase
KFV34_RS09965	COG2890	protein-(glutamine-N5) methyltransferase activity
KFV34_RS09970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFV34_RS09975	COG1435	thymidine kinase activity
KFV34_RS09980	COG0254	rRNA binding
KFV34_RS09985	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFV34_RS09990	COG1012	belongs to the aldehyde dehydrogenase family
KFV34_RS09995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFV34_RS10000	COG0191	fructose-bisphosphate aldolase activity
KFV34_RS10010	COG0504	CTP synthase activity
KFV34_RS10015	COG3343	RNA polymerase activity
KFV34_RS10025	COG5146	pantothenate kinase activity
KFV34_RS10045	COG1854	S-ribosylhomocysteine lyase activity
KFV34_RS10055	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KFV34_RS10060	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KFV34_RS10065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KFV34_RS10070	COG0813	purine-nucleoside phosphorylase activity
KFV34_RS10075	COG0783	Belongs to the Dps family
KFV34_RS10095	COG1482	cell wall glycoprotein biosynthetic process
KFV34_RS10100	COG0702	epimerase
KFV34_RS10105	COG0640	Transcriptional regulator
KFV34_RS10125	COG0561	phosphatase activity
KFV34_RS10130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFV34_RS10135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFV34_RS10145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KFV34_RS10195	COG0489	protein tyrosine kinase activity
KFV34_RS10200	COG2814	Major facilitator Superfamily
KFV34_RS10220	COG4284	Utp--glucose-1-phosphate uridylyltransferase
KFV34_RS10225	COG1988	membrane-bound metal-dependent
KFV34_RS10235	COG2329	Antibiotic biosynthesis monooxygenase
KFV34_RS10240	COG3314	Sporulation integral membrane protein YlbJ
KFV34_RS10245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFV34_RS10250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFV34_RS10255	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KFV34_RS10260	COG3457	Alanine racemase
KFV34_RS10265	COG4264	IucA IucC family
KFV34_RS10270	COG2814	Major facilitator Superfamily
KFV34_RS10275	COG4264	IucA IucC family
KFV34_RS10280	COG1302	Protein conserved in bacteria
KFV34_RS10295	COG0604	alcohol dehydrogenase
KFV34_RS10300	COG2130	NADP-dependent
KFV34_RS10305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFV34_RS10315	COG2723	6-phospho-beta-galactosidase activity
KFV34_RS10320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KFV34_RS10320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KFV34_RS10325	COG1447	Phosphotransferase system cellobiose-specific component IIA
KFV34_RS10330	COG3684	Belongs to the aldolase LacD family
KFV34_RS10335	COG1105	Belongs to the carbohydrate kinase PfkB family
KFV34_RS10340	COG0698	ribose 5-phosphate isomerase
KFV34_RS10345	COG0698	ribose 5-phosphate isomerase
KFV34_RS10350	COG1349	DNA-binding transcription factor activity
KFV34_RS10355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KFV34_RS10360	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KFV34_RS10365	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KFV34_RS10370	COG0101	tRNA pseudouridine synthase activity
KFV34_RS10380	COG1122	ATPase activity
KFV34_RS10385	COG1122	ATPase activity
KFV34_RS10390	COG0203	ribosomal protein L17
KFV34_RS10395	COG0202	RNA polymerase activity
KFV34_RS10400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KFV34_RS10405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KFV34_RS10410	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KFV34_RS10415	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KFV34_RS10420	COG0563	adenylate kinase activity
KFV34_RS10425	COG0201	protein transport
KFV34_RS10430	COG0200	Binds to the 23S rRNA
KFV34_RS10435	COG1841	ribosomal large subunit assembly
KFV34_RS10440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KFV34_RS10445	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KFV34_RS10450	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KFV34_RS10455	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KFV34_RS10460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFV34_RS10465	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFV34_RS10470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFV34_RS10475	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KFV34_RS10480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFV34_RS10490	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KFV34_RS10495	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KFV34_RS10500	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KFV34_RS10505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KFV34_RS10510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFV34_RS10515	COG0089	rRNA binding
KFV34_RS10520	COG0088	Forms part of the polypeptide exit tunnel
KFV34_RS10525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KFV34_RS10540	COG2252	PERMEase
KFV34_RS10545	COG0551	DNA topoisomerase type I activity
KFV34_RS10545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFV34_RS10550	COG4975	Glucose uptake
KFV34_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
KFV34_RS10575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFV34_RS10580	COG2348	transferase activity, transferring amino-acyl groups
KFV34_RS10595	COG2814	Major facilitator Superfamily
KFV34_RS10620	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFV34_RS10625	COG1074	ATP-dependent DNA helicase activity
KFV34_RS10630	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KFV34_RS10645	COG0398	Pfam SNARE associated Golgi protein
KFV34_RS10650	COG0166	Belongs to the GPI family
KFV34_RS10655	COG0137	argininosuccinate synthase activity
KFV34_RS10660	COG0165	Argininosuccinate lyase
KFV34_RS10665	COG0584	glycerophosphoryl diester phosphodiesterase
KFV34_RS10675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFV34_RS10685	COG1902	pentaerythritol trinitrate reductase activity
KFV34_RS10690	COG1098	S1 RNA binding domain
KFV34_RS10695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFV34_RS10705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFV34_RS10705	COG2111	Na H antiporter
KFV34_RS10710	COG2111	Na H antiporter
KFV34_RS10715	COG1006	Multisubunit Na H antiporter MnhC subunit
KFV34_RS10720	COG0651	ATP synthesis coupled electron transport
KFV34_RS10725	COG1863	multisubunit Na H antiporter MnhE subunit
KFV34_RS10730	COG2212	antiporter activity
KFV34_RS10735	COG1320	monovalent cation:proton antiporter activity
KFV34_RS10745	COG2050	protein possibly involved in aromatic compounds catabolism
KFV34_RS10750	COG2056	Na+-H+ antiporter family
KFV34_RS10755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFV34_RS10760	COG1252	NADH dehydrogenase
KFV34_RS10765	COG0316	Belongs to the HesB IscA family
KFV34_RS10770	COG4844	belongs to the
KFV34_RS10775	COG1252	NADH dehydrogenase
KFV34_RS10780	COG4837	Protein of unknown function (DUF1462)
KFV34_RS10785	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KFV34_RS10790	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KFV34_RS10795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFV34_RS10800	COG1696	Membrane protein involved in D-alanine export
KFV34_RS10805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFV34_RS10815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFV34_RS10820	COG0647	UMP catabolic process
KFV34_RS10825	COG2445	Protein of unknown function DUF86
KFV34_RS10835	COG4470	Protein conserved in bacteria
KFV34_RS10840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KFV34_RS10845	COG0737	Belongs to the 5'-nucleotidase family
KFV34_RS10850	COG0730	response to heat
KFV34_RS10855	COG1801	Protein of unknown function DUF72
KFV34_RS10860	COG1253	flavin adenine dinucleotide binding
KFV34_RS10875	COG0719	Fe-S assembly protein
KFV34_RS10880	COG0822	iron-sulfur transferase activity
KFV34_RS10885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFV34_RS10890	COG0719	Fe-S assembly protein
KFV34_RS10895	COG0396	ATPase activity
KFV34_RS10905	COG3237	CsbD-like
KFV34_RS10915	COG1464	Belongs to the NlpA lipoprotein family
KFV34_RS10920	COG2011	ABC-type metal ion transport system permease component
KFV34_RS10925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFV34_RS10935	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KFV34_RS10940	COG0509	glycine decarboxylation via glycine cleavage system
KFV34_RS10945	COG1393	Belongs to the ArsC family
KFV34_RS10950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFV34_RS10960	COG0710	3-dehydroquinate dehydratase activity
KFV34_RS10965	COG1764	response to oxidative stress
KFV34_RS11010	COG4195	phage-related replication protein
KFV34_RS11025	COG1278	Cold shock
KFV34_RS11055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFV34_RS11095	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFV34_RS11100	COG0557	exoribonuclease II activity
KFV34_RS11105	COG1647	Serine aminopeptidase, S33
KFV34_RS11110	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFV34_RS11120	COG0148	phosphopyruvate hydratase activity
KFV34_RS11125	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KFV34_RS11130	COG0149	triose-phosphate isomerase activity
KFV34_RS11135	COG0126	phosphoglycerate kinase activity
KFV34_RS11140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFV34_RS11160	COG1090	epimerase
KFV34_RS11170	COG0740	serine-type endopeptidase activity
KFV34_RS11180	COG1481	regulation of sporulation
KFV34_RS11185	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KFV34_RS11190	COG1660	Displays ATPase and GTPase activities
KFV34_RS11195	COG0492	ferredoxin-NADP+ reductase activity
KFV34_RS11210	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KFV34_RS11215	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KFV34_RS11220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFV34_RS11225	COG0556	nucleotide-excision repair
KFV34_RS11240	COG3942	CHAP domain
KFV34_RS11240	COG1388	LysM domain
KFV34_RS11250	COG0653	protein targeting
KFV34_RS11255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KFV34_RS11260	COG1040	competence protein
KFV34_RS11265	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KFV34_RS11275	COG1739	Uncharacterized protein family UPF0029
KFV34_RS11280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFV34_RS11285	COG2199	diguanylate cyclase activity
KFV34_RS11300	COG2195	Cleaves the N-terminal amino acid of tripeptides
KFV34_RS11305	COG1929	Belongs to the glycerate kinase type-1 family
KFV34_RS11325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFV34_RS11340	COG4604	ABC transporter, ATP-binding protein
KFV34_RS11350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFV34_RS11360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFV34_RS11365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFV34_RS11370	COG1780	Probably involved in ribonucleotide reductase function
KFV34_RS11380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFV34_RS11385	COG3104	oligopeptide transport
KFV34_RS11395	COG1597	lipid kinase activity
KFV34_RS11400	COG1012	belongs to the aldehyde dehydrogenase family
KFV34_RS11400	COG1454	alcohol dehydrogenase
KFV34_RS11405	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KFV34_RS11410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFV34_RS11415	COG1174	glycine betaine transport
KFV34_RS11425	COG0514	ATP-dependent DNA helicase (RecQ)
KFV34_RS11430	COG0488	(ABC) transporter
KFV34_RS11445	COG1368	sulfuric ester hydrolase activity
KFV34_RS11455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KFV34_RS11470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFV34_RS11480	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFV34_RS11485	COG0720	synthase
KFV34_RS11490	COG0602	queuosine metabolic process
KFV34_RS11515	COG0745	RESPONSE REGULATOR receiver
KFV34_RS11520	COG5002	protein histidine kinase activity
KFV34_RS11525	COG0463	Glycosyl transferase, family 2
KFV34_RS11530	COG0656	L-ascorbic acid biosynthetic process
KFV34_RS11535	COG1253	flavin adenine dinucleotide binding
KFV34_RS11540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KFV34_RS11545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFV34_RS11545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KFV34_RS11545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFV34_RS11550	COG1105	Belongs to the carbohydrate kinase PfkB family
KFV34_RS11555	COG1349	DNA-binding transcription factor activity
KFV34_RS11560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KFV34_RS11585	COG0415	Belongs to the DNA photolyase family
KFV34_RS11595	COG0471	metal ion transport
KFV34_RS11600	COG0039	L-malate dehydrogenase activity
KFV34_RS11620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KFV34_RS11625	COG4988	ABC transporter
KFV34_RS11630	COG1968	undecaprenyl-diphosphatase activity
KFV34_RS11645	COG1671	Belongs to the UPF0178 family
KFV34_RS11650	COG1611	Belongs to the LOG family
KFV34_RS11675	COG2839	Protein conserved in bacteria
KFV34_RS11680	COG2814	Major facilitator Superfamily
KFV34_RS11685	COG0583	DNA-binding transcription factor activity
KFV34_RS11705	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KFV34_RS11715	COG0217	transcriptional regulatory protein
KFV34_RS11735	COG1388	LysM domain
KFV34_RS11735	COG3942	CHAP domain
KFV34_RS11740	COG0306	phosphate transporter
KFV34_RS11745	COG1392	Phosphate transport regulator
KFV34_RS11750	COG0577	efflux transmembrane transporter activity
KFV34_RS11755	COG1136	(ABC) transporter
KFV34_RS11760	COG2205	protein histidine kinase activity
KFV34_RS11765	COG0745	RESPONSE REGULATOR receiver
KFV34_RS11770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFV34_RS11785	COG3949	Membrane
KFV34_RS11795	COG1120	ATPase activity
KFV34_RS11800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KFV34_RS11805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFV34_RS11815	COG1132	(ABC) transporter
KFV34_RS11820	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KFV34_RS11830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV34_RS11835	COG1682	transport, permease protein
KFV34_RS11840	COG1134	teichoic acid transport
KFV34_RS11845	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KFV34_RS11855	COG1321	iron dependent repressor
KFV34_RS11860	COG1121	(ABC) transporter
KFV34_RS11865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KFV34_RS11870	COG0803	Belongs to the bacterial solute-binding protein 9 family
KFV34_RS11880	COG1320	monovalent cation:proton antiporter activity
KFV34_RS11885	COG2212	antiporter activity
KFV34_RS11890	COG1863	multisubunit Na H antiporter MnhE subunit
KFV34_RS11895	COG0651	ATP synthesis coupled electron transport
KFV34_RS11900	COG1006	Multisubunit Na H antiporter MnhC subunit
KFV34_RS11905	COG2111	Na H antiporter
KFV34_RS11910	COG2111	Na H antiporter
KFV34_RS11910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFV34_RS11940	COG0596	Alpha beta hydrolase
KFV34_RS11960	COG0546	phosphoglycolate phosphatase activity
KFV34_RS11965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFV34_RS11970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KFV34_RS11980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFV34_RS11985	COG0018	arginyl-trna synthetase
KFV34_RS12000	COG1064	alcohol dehydrogenase
KFV34_RS12005	COG3875	lactate racemase activity
KFV34_RS12010	COG1606	tRNA processing
KFV34_RS12015	COG1691	(AIR) carboxylase
KFV34_RS12020	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KFV34_RS12030	COG1078	dGTPase activity
KFV34_RS12040	COG0667	Aldo Keto reductase
KFV34_RS12050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFV34_RS12055	COG4844	belongs to the
KFV34_RS12075	COG0095	Lipoate-protein ligase
KFV34_RS12080	COG0280	phosphate acetyltransferase
KFV34_RS12085	COG3253	May function as heme-dependent peroxidase
KFV34_RS12110	COG0531	amino acid
KFV34_RS12115	COG2363	Small membrane protein
KFV34_RS12125	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFV34_RS12135	COG0351	phosphomethylpyrimidine kinase
KFV34_RS12155	COG0183	Belongs to the thiolase family
KFV34_RS12160	COG0318	PFAM AMP-dependent synthetase and ligase
KFV34_RS12175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KFV34_RS12180	COG0363	glucosamine-6-phosphate deaminase activity
KFV34_RS12190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KFV34_RS12195	COG1469	GTP cyclohydrolase I activity
KFV34_RS12220	COG0431	NADPH-dependent FMN reductase
KFV34_RS12225	COG0561	phosphatase activity
KFV34_RS12235	COG1428	Deoxynucleoside kinase
KFV34_RS12240	COG1428	Deoxynucleoside kinase
KFV34_RS12245	COG1028	Short-chain dehydrogenase reductase Sdr
KFV34_RS12250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFV34_RS12255	COG0546	phosphoglycolate phosphatase activity
KFV34_RS12260	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFV34_RS12265	COG1063	alcohol dehydrogenase
KFV34_RS12270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFV34_RS12275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFV34_RS12280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFV34_RS12300	COG1473	amidohydrolase
KFV34_RS12305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFV34_RS12310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFV34_RS12320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KFV34_RS12330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFV34_RS12335	COG0085	RNA polymerase activity
KFV34_RS12340	COG2813	Specifically methylates the guanine in position
KFV34_RS12345	COG0222	ribosome binding
KFV34_RS12350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KFV34_RS12355	COG0081	regulation of translation
KFV34_RS12360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFV34_RS12365	COG0250	Participates in transcription elongation, termination and antitermination
KFV34_RS12370	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFV34_RS12375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KFV34_RS12385	COG3688	RNA-binding protein containing a PIN domain
KFV34_RS12390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFV34_RS12395	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KFV34_RS12400	COG0215	cysteine-tRNA ligase activity
KFV34_RS12405	COG1045	serine acetyltransferase
KFV34_RS12410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFV34_RS12415	COG4956	integral membrane protein (PIN domain superfamily)
KFV34_RS12420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KFV34_RS12425	COG0542	response to heat
KFV34_RS12430	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KFV34_RS12435	COG3880	PFAM UvrB UvrC protein
KFV34_RS12440	COG4463	regulation of RNA biosynthetic process
KFV34_RS12445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFV34_RS12455	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KFV34_RS12460	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KFV34_RS12465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFV34_RS12535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KFV34_RS12540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFV34_RS12545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFV34_RS12550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFV34_RS12555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KFV34_RS12560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFV34_RS12565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFV34_RS12570	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFV34_RS12575	COG0037	tRNA processing
KFV34_RS12580	COG1098	S1 RNA binding domain
KFV34_RS12590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KFV34_RS12595	COG3956	TIGRFAM MazG family protein
KFV34_RS12600	COG2244	polysaccharide biosynthetic process
KFV34_RS12605	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFV34_RS12610	COG0193	aminoacyl-tRNA hydrolase activity
KFV34_RS12615	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KFV34_RS12620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFV34_RS12625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFV34_RS12630	COG2088	sporulation resulting in formation of a cellular spore
KFV34_RS12635	COG0251	oxidation-reduction process
KFV34_RS12640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KFV34_RS12645	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KFV34_RS12650	COG4466	Protein conserved in bacteria
KFV34_RS12655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFV34_RS12660	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KFV34_RS12665	COG0084	hydrolase, TatD family'
KFV34_RS12670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFV34_RS12670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFV34_RS12675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KFV34_RS12680	COG2827	Endonuclease containing a URI domain
KFV34_RS12685	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KFV34_RS12690	COG4467	Involved in initiation control of chromosome replication
KFV34_RS12695	COG1774	PSP1 C-terminal conserved region
KFV34_RS12700	COG0470	DNA polymerase III
KFV34_RS12705	COG3870	Protein conserved in bacteria
KFV34_RS12710	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFV34_RS12715	COG1982	Orn Lys Arg decarboxylase major
KFV34_RS12740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KFV34_RS12745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KFV34_RS12750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KFV34_RS12770	COG2855	membrane
KFV34_RS12775	COG0583	DNA-binding transcription factor activity
KFV34_RS12785	COG0493	'glutamate synthase
KFV34_RS12790	COG0067	glutamate synthase
KFV34_RS12790	COG0069	glutamate synthase activity
KFV34_RS12790	COG0070	glutamate synthase
KFV34_RS12795	COG0583	DNA-binding transcription factor activity
KFV34_RS12820	COG0438	transferase activity, transferring glycosyl groups
KFV34_RS12825	COG1388	LysM domain
KFV34_RS12825	COG3942	CHAP domain
KFV34_RS12835	COG2011	ABC-type metal ion transport system permease component
KFV34_RS12840	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFV34_RS12845	COG0626	cystathionine gamma-synthase activity
KFV34_RS12850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KFV34_RS12860	COG0733	neurotransmitter:sodium symporter activity
KFV34_RS12870	COG1647	Serine aminopeptidase, S33
KFV34_RS12885	COG5609	conserved protein (DUF2294)
KFV34_RS12890	COG3002	Belongs to the UPF0753 family
KFV34_RS12895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFV34_RS12915	COG0523	cobalamin synthesis protein
KFV34_RS12955	COG0519	Catalyzes the synthesis of GMP from XMP
KFV34_RS12955	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFV34_RS12960	COG0516	GMP reductase activity
KFV34_RS12960	COG0517	IMP dehydrogenase activity
KFV34_RS12965	COG2233	PERMEase
KFV34_RS12970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KFV34_RS12985	COG5183	chlorophyll binding
KFV34_RS12990	COG1823	symporter activity
KFV34_RS12995	COG0778	Nitroreductase
KFV34_RS13005	COG0450	alkyl hydroperoxide reductase
KFV34_RS13010	COG3634	alkyl hydroperoxide reductase activity
KFV34_RS13030	COG1280	lysine exporter protein (LysE YggA)
KFV34_RS13045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KFV34_RS13055	COG0360	Binds together with S18 to 16S ribosomal RNA
KFV34_RS13070	COG0012	GTP binding
KFV34_RS13075	COG4481	Protein conserved in bacteria
KFV34_RS13080	COG0668	transmembrane transport
KFV34_RS13085	COG1475	DNA binding
KFV34_RS13090	COG0626	cystathionine gamma-synthase activity
KFV34_RS13095	COG0626	cystathionine gamma-synthase activity
KFV34_RS13100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFV34_RS13100	COG0646	methionine synthase
KFV34_RS13105	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KFV34_RS13115	COG0183	Belongs to the thiolase family
KFV34_RS13130	COG1476	TRANSCRIPTIONal
KFV34_RS13170	COG1136	(ABC) transporter
KFV34_RS13175	COG0577	efflux transmembrane transporter activity
KFV34_RS13190	COG0577	efflux transmembrane transporter activity
KFV34_RS13195	COG1136	(ABC) transporter
KFV34_RS13230	COG1475	DNA binding
KFV34_RS13235	COG0357	Ribosomal RNA small subunit methyltransferase G
KFV34_RS13240	COG0445	tRNA wobble uridine modification
KFV34_RS13245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KFV34_RS13250	COG0594	ribonuclease P activity
KFV34_RS13340	COG2314	TM2 domain