locus-tag	class	description
EH162_RS00100	COG0756	dUTP diphosphatase activity
EH162_RS00180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EH162_RS00240	COG4873	Protein conserved in bacteria
EH162_RS00250	COG0737	Belongs to the 5'-nucleotidase family
EH162_RS00255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EH162_RS00260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH162_RS00265	COG0861	Integral membrane protein TerC family
EH162_RS00270	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EH162_RS00280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EH162_RS00285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EH162_RS00290	COG2814	Major facilitator Superfamily
EH162_RS00295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EH162_RS00300	COG2382	esterase
EH162_RS00305	COG0628	permease
EH162_RS00340	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EH162_RS00345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EH162_RS00350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EH162_RS00385	COG0475	glutathione-regulated potassium exporter activity
EH162_RS00385	COG0569	domain protein
EH162_RS00390	COG2239	Acts as a magnesium transporter
EH162_RS00395	COG0564	pseudouridine synthase activity
EH162_RS00400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EH162_RS00405	COG2357	RelA SpoT domain protein
EH162_RS00420	COG2346	COG2346, Truncated hemoglobins
EH162_RS00425	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EH162_RS00430	COG1164	Oligoendopeptidase f
EH162_RS00440	COG4862	establishment of competence for transformation
EH162_RS00450	COG1393	Belongs to the ArsC family
EH162_RS00455	COG0180	Tryptophanyl-tRNA synthetase
EH162_RS00460	COG4166	transmembrane transport
EH162_RS00465	COG4608	Belongs to the ABC transporter superfamily
EH162_RS00470	COG0444	Belongs to the ABC transporter superfamily
EH162_RS00475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH162_RS00480	COG0601	transmembrane transport
EH162_RS00495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EH162_RS00525	COG0542	response to heat
EH162_RS00540	COG0561	phosphatase activity
EH162_RS00545	COG0446	pyridine nucleotide-disulphide oxidoreductase
EH162_RS00555	COG0179	Fumarylacetoacetate (FAA) hydrolase
EH162_RS00560	COG1074	ATP-dependent DNA helicase activity
EH162_RS00565	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EH162_RS00580	COG0398	Pfam SNARE associated Golgi protein
EH162_RS00590	COG0166	Belongs to the GPI family
EH162_RS00595	COG0137	argininosuccinate synthase activity
EH162_RS00600	COG0165	Argininosuccinate lyase
EH162_RS00605	COG0584	glycerophosphoryl diester phosphodiesterase
EH162_RS00615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH162_RS00620	COG1902	pentaerythritol trinitrate reductase activity
EH162_RS00630	COG1098	S1 RNA binding domain
EH162_RS00635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH162_RS00645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH162_RS00645	COG2111	Na H antiporter
EH162_RS00650	COG2111	Na H antiporter
EH162_RS00655	COG1006	Multisubunit Na H antiporter MnhC subunit
EH162_RS00660	COG0651	ATP synthesis coupled electron transport
EH162_RS00665	COG1863	multisubunit Na H antiporter MnhE subunit
EH162_RS00670	COG2212	antiporter activity
EH162_RS00675	COG1320	monovalent cation:proton antiporter activity
EH162_RS00685	COG2050	protein possibly involved in aromatic compounds catabolism
EH162_RS00690	COG2056	Na+-H+ antiporter family
EH162_RS00695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EH162_RS00700	COG1252	NADH dehydrogenase
EH162_RS00705	COG0316	Belongs to the HesB IscA family
EH162_RS00710	COG4844	belongs to the
EH162_RS00715	COG1252	NADH dehydrogenase
EH162_RS00720	COG4837	Protein of unknown function (DUF1462)
EH162_RS00725	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EH162_RS00730	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EH162_RS00735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH162_RS00740	COG1696	Membrane protein involved in D-alanine export
EH162_RS00745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH162_RS00755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH162_RS00760	COG0647	UMP catabolic process
EH162_RS00765	COG2445	Protein of unknown function DUF86
EH162_RS00775	COG4470	Protein conserved in bacteria
EH162_RS00780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EH162_RS00785	COG0737	Belongs to the 5'-nucleotidase family
EH162_RS00790	COG0730	response to heat
EH162_RS00795	COG1801	Protein of unknown function DUF72
EH162_RS00800	COG1253	flavin adenine dinucleotide binding
EH162_RS00815	COG0719	Fe-S assembly protein
EH162_RS00820	COG0822	iron-sulfur transferase activity
EH162_RS00825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH162_RS00830	COG0719	Fe-S assembly protein
EH162_RS00835	COG0396	ATPase activity
EH162_RS00845	COG3237	CsbD-like
EH162_RS00855	COG1464	Belongs to the NlpA lipoprotein family
EH162_RS00860	COG2011	ABC-type metal ion transport system permease component
EH162_RS00865	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH162_RS00875	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EH162_RS00885	COG0509	glycine decarboxylation via glycine cleavage system
EH162_RS00890	COG1393	Belongs to the ArsC family
EH162_RS00895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH162_RS00905	COG0710	3-dehydroquinate dehydratase activity
EH162_RS00910	COG1764	response to oxidative stress
EH162_RS00965	COG4195	phage-related replication protein
EH162_RS00980	COG1278	Cold shock
EH162_RS01025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EH162_RS01065	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EH162_RS01070	COG0557	exoribonuclease II activity
EH162_RS01075	COG1647	Serine aminopeptidase, S33
EH162_RS01080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EH162_RS01090	COG0148	phosphopyruvate hydratase activity
EH162_RS01095	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EH162_RS01100	COG0149	triose-phosphate isomerase activity
EH162_RS01105	COG0126	phosphoglycerate kinase activity
EH162_RS01110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EH162_RS01130	COG1090	epimerase
EH162_RS01140	COG0740	serine-type endopeptidase activity
EH162_RS01150	COG1481	regulation of sporulation
EH162_RS01155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EH162_RS01160	COG1660	Displays ATPase and GTPase activities
EH162_RS01165	COG0492	ferredoxin-NADP+ reductase activity
EH162_RS01180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EH162_RS01185	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EH162_RS01190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EH162_RS01195	COG0556	nucleotide-excision repair
EH162_RS01215	COG1388	LysM domain
EH162_RS01215	COG3942	CHAP domain
EH162_RS01225	COG0653	protein targeting
EH162_RS01230	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EH162_RS01235	COG1040	competence protein
EH162_RS01240	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EH162_RS01250	COG1739	Uncharacterized protein family UPF0029
EH162_RS01255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH162_RS01260	COG2199	diguanylate cyclase activity
EH162_RS01275	COG2195	Cleaves the N-terminal amino acid of tripeptides
EH162_RS01280	COG1929	Belongs to the glycerate kinase type-1 family
EH162_RS01300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EH162_RS01315	COG4604	ABC transporter, ATP-binding protein
EH162_RS01320	COG4605	iron ion homeostasis
EH162_RS01325	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH162_RS01335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EH162_RS01340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EH162_RS01345	COG1780	Probably involved in ribonucleotide reductase function
EH162_RS01355	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EH162_RS01360	COG3104	oligopeptide transport
EH162_RS01365	COG1597	lipid kinase activity
EH162_RS01370	COG1454	alcohol dehydrogenase
EH162_RS01370	COG1012	belongs to the aldehyde dehydrogenase family
EH162_RS01375	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EH162_RS01380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH162_RS01385	COG1174	glycine betaine transport
EH162_RS01395	COG0514	ATP-dependent DNA helicase (RecQ)
EH162_RS01400	COG0488	(ABC) transporter
EH162_RS01420	COG1368	sulfuric ester hydrolase activity
EH162_RS01430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EH162_RS01445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EH162_RS01455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EH162_RS01460	COG0720	synthase
EH162_RS01465	COG0602	queuosine metabolic process
EH162_RS01495	COG0745	RESPONSE REGULATOR receiver
EH162_RS01500	COG5002	protein histidine kinase activity
EH162_RS01505	COG0463	Glycosyl transferase, family 2
EH162_RS01515	COG0656	L-ascorbic acid biosynthetic process
EH162_RS01520	COG1253	flavin adenine dinucleotide binding
EH162_RS01525	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EH162_RS01530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH162_RS01530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH162_RS01530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH162_RS01535	COG1105	Belongs to the carbohydrate kinase PfkB family
EH162_RS01540	COG1349	DNA-binding transcription factor activity
EH162_RS01550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EH162_RS01575	COG0415	Belongs to the DNA photolyase family
EH162_RS01580	COG0471	metal ion transport
EH162_RS01585	COG0039	L-malate dehydrogenase activity
EH162_RS01610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EH162_RS01615	COG4988	ABC transporter
EH162_RS01620	COG1968	undecaprenyl-diphosphatase activity
EH162_RS01635	COG1671	Belongs to the UPF0178 family
EH162_RS01640	COG1611	Belongs to the LOG family
EH162_RS01665	COG2839	Protein conserved in bacteria
EH162_RS01670	COG2814	Major facilitator Superfamily
EH162_RS01675	COG0583	DNA-binding transcription factor activity
EH162_RS01695	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EH162_RS01705	COG0217	transcriptional regulatory protein
EH162_RS01725	COG1388	LysM domain
EH162_RS01725	COG3942	CHAP domain
EH162_RS01730	COG0306	phosphate transporter
EH162_RS01735	COG1392	Phosphate transport regulator
EH162_RS01740	COG0577	efflux transmembrane transporter activity
EH162_RS01745	COG1136	(ABC) transporter
EH162_RS01750	COG2205	protein histidine kinase activity
EH162_RS01755	COG0745	RESPONSE REGULATOR receiver
EH162_RS01760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH162_RS01775	COG3949	Membrane
EH162_RS01785	COG1120	ATPase activity
EH162_RS01790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EH162_RS01800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH162_RS01805	COG1132	(ABC) transporter
EH162_RS01820	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EH162_RS01830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EH162_RS01835	COG1682	transport, permease protein
EH162_RS01840	COG1134	teichoic acid transport
EH162_RS01845	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EH162_RS01855	COG1321	iron dependent repressor
EH162_RS01860	COG1121	(ABC) transporter
EH162_RS01865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH162_RS01870	COG0803	Belongs to the bacterial solute-binding protein 9 family
EH162_RS01880	COG1320	monovalent cation:proton antiporter activity
EH162_RS01885	COG2212	antiporter activity
EH162_RS01890	COG1863	multisubunit Na H antiporter MnhE subunit
EH162_RS01895	COG0651	ATP synthesis coupled electron transport
EH162_RS01900	COG1006	Multisubunit Na H antiporter MnhC subunit
EH162_RS01905	COG2111	Na H antiporter
EH162_RS01910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH162_RS01910	COG2111	Na H antiporter
EH162_RS01960	COG0596	Alpha beta hydrolase
EH162_RS01980	COG0546	phosphoglycolate phosphatase activity
EH162_RS01985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH162_RS01990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH162_RS02005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EH162_RS02010	COG0018	arginyl-trna synthetase
EH162_RS02035	COG1064	alcohol dehydrogenase
EH162_RS02040	COG3875	lactate racemase activity
EH162_RS02045	COG1606	tRNA processing
EH162_RS02050	COG1691	(AIR) carboxylase
EH162_RS02055	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EH162_RS02065	COG1078	dGTPase activity
EH162_RS02075	COG0667	Aldo Keto reductase
EH162_RS02085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH162_RS02090	COG4844	belongs to the
EH162_RS02110	COG0095	Lipoate-protein ligase
EH162_RS02115	COG0280	phosphate acetyltransferase
EH162_RS02120	COG3253	May function as heme-dependent peroxidase
EH162_RS02135	COG0531	amino acid
EH162_RS02140	COG2363	Small membrane protein
EH162_RS02150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EH162_RS02160	COG0351	phosphomethylpyrimidine kinase
EH162_RS02180	COG0183	Belongs to the thiolase family
EH162_RS02185	COG0318	PFAM AMP-dependent synthetase and ligase
EH162_RS02195	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EH162_RS02200	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EH162_RS02205	COG0363	glucosamine-6-phosphate deaminase activity
EH162_RS02215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EH162_RS02220	COG1469	GTP cyclohydrolase I activity
EH162_RS02230	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EH162_RS02235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EH162_RS02240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EH162_RS02255	COG0431	NADPH-dependent FMN reductase
EH162_RS02260	COG0561	phosphatase activity
EH162_RS02275	COG1428	Deoxynucleoside kinase
EH162_RS02280	COG1428	Deoxynucleoside kinase
EH162_RS02290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH162_RS02295	COG0546	phosphoglycolate phosphatase activity
EH162_RS02300	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EH162_RS02305	COG1063	alcohol dehydrogenase
EH162_RS02310	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EH162_RS02315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EH162_RS02320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH162_RS02340	COG1473	amidohydrolase
EH162_RS02345	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EH162_RS02350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EH162_RS02360	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EH162_RS02370	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EH162_RS02375	COG0085	RNA polymerase activity
EH162_RS02380	COG2813	Specifically methylates the guanine in position
EH162_RS02385	COG0222	ribosome binding
EH162_RS02390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EH162_RS02400	COG0081	regulation of translation
EH162_RS02405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EH162_RS02410	COG0250	Participates in transcription elongation, termination and antitermination
EH162_RS02415	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EH162_RS02420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EH162_RS02430	COG3688	RNA-binding protein containing a PIN domain
EH162_RS02435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH162_RS02440	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EH162_RS02445	COG0215	cysteine-tRNA ligase activity
EH162_RS02450	COG1045	serine acetyltransferase
EH162_RS02455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH162_RS02460	COG4956	integral membrane protein (PIN domain superfamily)
EH162_RS02465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EH162_RS02470	COG0542	response to heat
EH162_RS02475	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EH162_RS02480	COG3880	PFAM UvrB UvrC protein
EH162_RS02485	COG4463	regulation of RNA biosynthetic process
EH162_RS02490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH162_RS02500	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EH162_RS02505	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EH162_RS02510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EH162_RS02595	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EH162_RS02600	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EH162_RS02605	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EH162_RS02610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EH162_RS02615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH162_RS02620	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EH162_RS02625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH162_RS02630	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EH162_RS02635	COG0037	tRNA processing
EH162_RS02640	COG1098	S1 RNA binding domain
EH162_RS02650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EH162_RS02655	COG3956	TIGRFAM MazG family protein
EH162_RS02660	COG2244	polysaccharide biosynthetic process
EH162_RS02665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EH162_RS02670	COG0193	aminoacyl-tRNA hydrolase activity
EH162_RS02675	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EH162_RS02680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EH162_RS02685	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EH162_RS02690	COG2088	sporulation resulting in formation of a cellular spore
EH162_RS02695	COG0251	oxidation-reduction process
EH162_RS02700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EH162_RS02705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EH162_RS02710	COG4466	Protein conserved in bacteria
EH162_RS02715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EH162_RS02720	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EH162_RS02725	COG0084	hydrolase, TatD family'
EH162_RS02730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH162_RS02730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH162_RS02735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EH162_RS02740	COG2827	Endonuclease containing a URI domain
EH162_RS02745	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EH162_RS02750	COG4467	Involved in initiation control of chromosome replication
EH162_RS02755	COG1774	PSP1 C-terminal conserved region
EH162_RS02760	COG0470	DNA polymerase III
EH162_RS02765	COG3870	Protein conserved in bacteria
EH162_RS02770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EH162_RS02775	COG1982	Orn Lys Arg decarboxylase major
EH162_RS02800	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EH162_RS02805	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EH162_RS02810	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EH162_RS02830	COG2855	membrane
EH162_RS02835	COG0583	DNA-binding transcription factor activity
EH162_RS02845	COG0493	'glutamate synthase
EH162_RS02850	COG0067	glutamate synthase
EH162_RS02850	COG0069	glutamate synthase activity
EH162_RS02850	COG0070	glutamate synthase
EH162_RS02855	COG0583	DNA-binding transcription factor activity
EH162_RS02880	COG0438	transferase activity, transferring glycosyl groups
EH162_RS02885	COG1388	LysM domain
EH162_RS02885	COG3942	CHAP domain
EH162_RS02895	COG2011	ABC-type metal ion transport system permease component
EH162_RS02900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EH162_RS02905	COG0626	cystathionine gamma-synthase activity
EH162_RS02910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH162_RS02920	COG0733	neurotransmitter:sodium symporter activity
EH162_RS02930	COG1647	Serine aminopeptidase, S33
EH162_RS02945	COG5609	conserved protein (DUF2294)
EH162_RS02955	COG3002	Belongs to the UPF0753 family
EH162_RS02960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH162_RS02980	COG0523	cobalamin synthesis protein
EH162_RS02995	COG0655	NAD(P)H dehydrogenase (quinone) activity
EH162_RS03030	COG0519	Catalyzes the synthesis of GMP from XMP
EH162_RS03030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EH162_RS03035	COG0517	IMP dehydrogenase activity
EH162_RS03035	COG0516	GMP reductase activity
EH162_RS03040	COG2233	PERMEase
EH162_RS03045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EH162_RS03060	COG5183	chlorophyll binding
EH162_RS03070	COG1823	symporter activity
EH162_RS03075	COG0778	Nitroreductase
EH162_RS03085	COG0450	alkyl hydroperoxide reductase
EH162_RS03090	COG3634	alkyl hydroperoxide reductase activity
EH162_RS03120	COG1280	lysine exporter protein (LysE YggA)
EH162_RS03145	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EH162_RS03155	COG0360	Binds together with S18 to 16S ribosomal RNA
EH162_RS03170	COG0012	GTP binding
EH162_RS03175	COG4481	Protein conserved in bacteria
EH162_RS03180	COG0668	transmembrane transport
EH162_RS03185	COG1475	DNA binding
EH162_RS03195	COG0626	cystathionine gamma-synthase activity
EH162_RS03200	COG0626	cystathionine gamma-synthase activity
EH162_RS03205	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EH162_RS03205	COG0646	methionine synthase
EH162_RS03210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EH162_RS03220	COG0183	Belongs to the thiolase family
EH162_RS03235	COG1476	TRANSCRIPTIONal
EH162_RS03245	COG4555	ABC transporter
EH162_RS03310	COG1136	(ABC) transporter
EH162_RS03315	COG0577	efflux transmembrane transporter activity
EH162_RS03330	COG0577	efflux transmembrane transporter activity
EH162_RS03335	COG1136	(ABC) transporter
EH162_RS03375	COG1475	DNA binding
EH162_RS03380	COG0357	Ribosomal RNA small subunit methyltransferase G
EH162_RS03385	COG0445	tRNA wobble uridine modification
EH162_RS03390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EH162_RS03395	COG0594	ribonuclease P activity
EH162_RS03405	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EH162_RS03410	COG0592	DNA-directed DNA polymerase activity
EH162_RS03415	COG2501	S4 domain
EH162_RS03420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH162_RS03425	COG0187	DNA topoisomerase II activity
EH162_RS03430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EH162_RS03435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EH162_RS03440	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EH162_RS03460	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EH162_RS03470	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EH162_RS03475	COG0359	binds to the 23S rRNA
EH162_RS03480	COG0305	Participates in initiation and elongation during chromosome replication
EH162_RS03485	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EH162_RS03505	COG0745	RESPONSE REGULATOR receiver
EH162_RS03510	COG5002	protein histidine kinase activity
EH162_RS03515	COG4863	YycH protein
EH162_RS03525	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EH162_RS03530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EH162_RS03535	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EH162_RS03560	COG3425	synthase
EH162_RS03570	COG0584	glycerophosphoryl diester phosphodiesterase
EH162_RS03575	COG2030	dehydratase
EH162_RS03665	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EH162_RS03675	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EH162_RS03680	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH162_RS03685	COG0210	DNA helicase
EH162_RS03695	COG0076	glutamate decarboxylase activity
EH162_RS03730	COG1131	(ABC) transporter
EH162_RS03745	COG0745	RESPONSE REGULATOR receiver
EH162_RS03750	COG5002	protein histidine kinase activity
EH162_RS03780	COG2217	Heavy metal translocating P-type atpase
EH162_RS03785	COG1388	LysM domain
EH162_RS03790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH162_RS03795	COG2210	Belongs to the sulfur carrier protein TusA family
EH162_RS03800	COG1937	Protein conserved in bacteria
EH162_RS03805	COG0730	response to heat
EH162_RS03810	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EH162_RS03815	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EH162_RS03835	COG0640	Transcriptional regulator
EH162_RS03840	COG0701	Predicted permease
EH162_RS03860	COG0668	transmembrane transport
EH162_RS03865	COG0561	phosphatase activity
EH162_RS03905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH162_RS03910	COG0579	oxidoreductase
EH162_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
EH162_RS03935	COG1755	Isoprenylcysteine carboxyl methyltransferase
EH162_RS03945	COG4753	response regulator
EH162_RS03945	COG2207	Transcriptional regulator
EH162_RS03950	COG2972	Histidine kinase
EH162_RS04015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EH162_RS04020	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EH162_RS04025	COG0156	8-amino-7-oxononanoate synthase activity
EH162_RS04030	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EH162_RS04055	COG0523	cobalamin synthesis protein
EH162_RS04080	COG0431	NADPH-dependent FMN reductase
EH162_RS04080	COG1053	succinate dehydrogenase
EH162_RS04080	COG3976	FMN-binding domain protein
EH162_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
EH162_RS04130	COG0601	transmembrane transport
EH162_RS04140	COG0444	Belongs to the ABC transporter superfamily
EH162_RS04145	COG1124	(ABC) transporter
EH162_RS04155	COG1882	Formate acetyltransferase
EH162_RS04160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EH162_RS04165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH162_RS04170	COG1114	Component of the transport system for branched-chain amino acids
EH162_RS04175	COG1309	transcriptional regulator
EH162_RS04180	COG3246	L-lysine catabolic process to acetate
EH162_RS04185	COG1250	3-hydroxyacyl-CoA dehydrogenase
EH162_RS04220	COG1288	antiporter activity
EH162_RS04225	COG0549	Belongs to the carbamate kinase family
EH162_RS04230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EH162_RS04240	COG0346	lactoylglutathione lyase activity
EH162_RS04245	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EH162_RS04250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EH162_RS04260	COG2376	Dihydroxyacetone kinase
EH162_RS04265	COG1461	Dihydroxyacetone kinase
EH162_RS04270	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EH162_RS04280	COG2814	Major facilitator Superfamily
EH162_RS04285	COG0583	DNA-binding transcription factor activity
EH162_RS04295	COG2814	Major facilitator Superfamily
EH162_RS04330	COG2814	Major facilitator Superfamily
EH162_RS04345	COG2962	Rard protein
EH162_RS04350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH162_RS04355	COG0471	metal ion transport
EH162_RS04360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH162_RS04365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EH162_RS04370	COG0022	dehydrogenase e1 component
EH162_RS04375	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH162_RS04395	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EH162_RS04400	COG1054	Belongs to the UPF0176 family
EH162_RS04405	COG3386	PFAM SMP-30 Gluconolaconase
EH162_RS04410	COG2353	YceI-like domain
EH162_RS04420	COG0579	oxidoreductase
EH162_RS04445	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EH162_RS04450	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EH162_RS04455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EH162_RS04460	COG0131	Imidazoleglycerol-phosphate dehydratase
EH162_RS04465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EH162_RS04470	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EH162_RS04475	COG0107	imidazoleglycerol-phosphate synthase activity
EH162_RS04480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EH162_RS04480	COG0140	phosphoribosyl-ATP diphosphatase activity
EH162_RS04485	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EH162_RS04495	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EH162_RS04505	COG0726	polysaccharide deacetylase
EH162_RS04515	COG1215	transferase activity, transferring glycosyl groups
EH162_RS04520	COG1309	transcriptional regulator
EH162_RS04535	COG2814	Major facilitator Superfamily
EH162_RS04540	COG0737	Belongs to the 5'-nucleotidase family
EH162_RS04555	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EH162_RS04560	COG3639	organic phosphonate transmembrane transporter activity
EH162_RS04580	COG0201	protein transport
EH162_RS04590	COG1073	alpha beta
EH162_RS04600	COG0653	protein targeting
EH162_RS04605	COG0438	transferase activity, transferring glycosyl groups
EH162_RS04630	COG2814	Major facilitator Superfamily
EH162_RS04635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH162_RS04650	COG1764	response to oxidative stress
EH162_RS04660	COG1705	Flagellar rod assembly protein muramidase FlgJ
EH162_RS04660	COG3942	CHAP domain
EH162_RS04670	COG1482	cell wall glycoprotein biosynthetic process
EH162_RS04675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH162_RS04675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EH162_RS04675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH162_RS04680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH162_RS04680	COG3711	transcriptional antiterminator
EH162_RS04710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH162_RS04720	COG1438	arginine binding
EH162_RS04725	COG2235	arginine
EH162_RS04730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EH162_RS04740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH162_RS04750	COG2843	Capsule synthesis protein
EH162_RS04760	COG3961	Belongs to the TPP enzyme family
EH162_RS04810	COG4195	phage-related replication protein
EH162_RS04820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EH162_RS04825	COG0702	epimerase
EH162_RS04830	COG1785	Belongs to the alkaline phosphatase family
EH162_RS04845	COG2205	protein histidine kinase activity
EH162_RS04850	COG1136	(ABC) transporter
EH162_RS04875	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EH162_RS04900	COG1846	Transcriptional regulator
EH162_RS04905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH162_RS04910	COG0386	Belongs to the glutathione peroxidase family
EH162_RS04920	COG0175	sulfate reduction
EH162_RS04925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EH162_RS04930	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH162_RS04945	COG0730	response to heat
EH162_RS04950	COG2046	Belongs to the sulfate adenylyltransferase family
EH162_RS04955	COG0529	Catalyzes the synthesis of activated sulfate
EH162_RS04965	COG1328	CTP reductase activity
EH162_RS04970	COG0602	queuosine metabolic process
EH162_RS04975	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EH162_RS04990	COG1510	regulation of RNA biosynthetic process
EH162_RS04995	COG1012	belongs to the aldehyde dehydrogenase family
EH162_RS05000	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EH162_RS05005	COG1473	amidohydrolase
EH162_RS05020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EH162_RS05025	COG0574	Belongs to the PEP-utilizing enzyme family
EH162_RS05025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH162_RS05030	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EH162_RS05035	COG0579	oxidoreductase
EH162_RS05045	COG3588	fructose-bisphosphate aldolase
EH162_RS05055	COG0446	pyridine nucleotide-disulphide oxidoreductase
EH162_RS05090	COG0531	amino acid
EH162_RS05095	COG0583	DNA-binding transcription factor activity
EH162_RS05100	COG0039	L-malate dehydrogenase activity
EH162_RS05105	COG0028	Belongs to the TPP enzyme family
EH162_RS05110	COG3527	Alpha-acetolactate decarboxylase
EH162_RS05120	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EH162_RS05125	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EH162_RS05130	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EH162_RS05145	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EH162_RS05155	COG0167	dihydroorotate dehydrogenase activity
EH162_RS05160	COG3001	Fructosamine kinase
EH162_RS05165	COG1113	amino acid transport
EH162_RS05185	COG0741	lytic transglycosylase activity
EH162_RS05195	COG3942	CHAP domain
EH162_RS05200	COG0436	Aminotransferase
EH162_RS05210	COG2608	mercury ion transmembrane transporter activity
EH162_RS05215	COG2217	Heavy metal translocating P-type atpase
EH162_RS05225	COG1028	Short-chain dehydrogenase reductase Sdr
EH162_RS05230	COG1012	belongs to the aldehyde dehydrogenase family
EH162_RS05255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EH162_RS05260	COG3425	synthase
EH162_RS05280	COG0583	DNA-binding transcription factor activity
EH162_RS05285	COG1380	Effector of murein hydrolase LrgA
EH162_RS05290	COG1346	cytolysis
EH162_RS05295	COG0028	Belongs to the TPP enzyme family
EH162_RS05300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH162_RS05300	COG1263	PTS System
EH162_RS05300	COG2190	(PTS) system
EH162_RS05315	COG1063	alcohol dehydrogenase
EH162_RS05320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH162_RS05325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EH162_RS05340	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EH162_RS05350	COG2843	Capsule synthesis protein
EH162_RS05365	COG4975	Glucose uptake
EH162_RS05370	COG1869	D-ribose catabolic process
EH162_RS05385	COG1070	Carbohydrate kinase
EH162_RS05405	COG1760	l-serine dehydratase
EH162_RS05410	COG1760	l-serine dehydratase
EH162_RS05425	COG3764	Sortase (surface protein transpeptidase)
EH162_RS05435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH162_RS05440	COG0778	Nitroreductase
EH162_RS05450	COG1012	belongs to the aldehyde dehydrogenase family
EH162_RS05460	COG2514	catechol 2,3-dioxygenase activity
EH162_RS05475	COG1012	belongs to the aldehyde dehydrogenase family
EH162_RS05480	COG3949	Membrane
EH162_RS05495	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EH162_RS05500	COG0586	Pfam SNARE associated Golgi protein
EH162_RS05505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EH162_RS05510	COG2022	thiamine diphosphate biosynthetic process
EH162_RS05520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH162_RS05535	COG2271	Major facilitator Superfamily
EH162_RS05550	COG4876	unkown
EH162_RS05555	COG2357	RelA SpoT domain protein
EH162_RS05575	COG0789	Transcriptional regulator
EH162_RS05580	COG2271	Major facilitator Superfamily
EH162_RS05585	COG1802	Transcriptional regulator
EH162_RS05595	COG2610	gluconate transmembrane transporter activity
EH162_RS05600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EH162_RS05605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EH162_RS05610	COG0438	transferase activity, transferring glycosyl groups
EH162_RS05615	COG0494	nUDIX hydrolase
EH162_RS05620	COG0556	nucleotide-excision repair
EH162_RS05635	COG4221	oxidoreductase activity
EH162_RS05640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH162_RS05645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EH162_RS05650	COG0248	Ppx GppA phosphatase
EH162_RS05655	COG1028	Short-chain dehydrogenase reductase Sdr
EH162_RS05665	COG1363	Peptidase, m42
EH162_RS05675	COG0069	glutamate synthase activity
EH162_RS05700	COG4619	ABC transporter
EH162_RS05705	COG0390	transport system, permease component
EH162_RS05710	COG2814	Major facilitator Superfamily
EH162_RS05715	COG2272	Belongs to the type-B carboxylesterase lipase family
EH162_RS05720	COG0531	amino acid
EH162_RS05725	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EH162_RS05730	COG1063	alcohol dehydrogenase
EH162_RS05750	COG1174	glycine betaine transport
EH162_RS05755	COG1346	cytolysis
EH162_RS05760	COG1380	Effector of murein hydrolase LrgA
EH162_RS05765	COG3279	Response regulator of the LytR AlgR family
EH162_RS05770	COG3275	phosphorelay sensor kinase activity
EH162_RS05780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EH162_RS05785	COG0706	membrane insertase activity
EH162_RS05795	COG0531	amino acid
EH162_RS05800	COG1113	amino acid transport
EH162_RS05825	COG1929	Belongs to the glycerate kinase type-1 family
EH162_RS05840	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EH162_RS05845	COG0588	phosphoglycerate mutase activity
EH162_RS05855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH162_RS05860	COG0765	amino acid transport
EH162_RS05865	COG1126	abc transporter atp-binding protein
EH162_RS05890	COG2116	formate transmembrane transporter activity
EH162_RS05895	COG0454	-acetyltransferase
EH162_RS05900	COG0747	negative chemotaxis
EH162_RS05915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH162_RS05920	COG2146	nitrite reductase [NAD(P)H] activity
EH162_RS05930	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EH162_RS05935	COG1140	nitrate reductase beta subunit
EH162_RS05945	COG2181	nitrate reductase activity
EH162_RS05955	COG4585	Histidine kinase
EH162_RS05960	COG2197	response regulator
EH162_RS05965	COG2223	nitrite transmembrane transporter activity
EH162_RS05970	COG1846	Transcriptional regulator
EH162_RS05975	COG0778	Nitroreductase
EH162_RS05995	COG3871	stress protein (general stress protein 26)
EH162_RS06010	COG1263	PTS System
EH162_RS06010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH162_RS06055	COG0604	alcohol dehydrogenase
EH162_RS06060	COG0456	acetyltransferase
EH162_RS06065	COG0463	Glycosyl transferase, family 2
EH162_RS06065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EH162_RS06075	COG0463	Glycosyl transferase, family 2
EH162_RS06075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EH162_RS06080	COG1620	l-lactate permease
EH162_RS06085	COG0438	transferase activity, transferring glycosyl groups
EH162_RS06090	COG0579	oxidoreductase
EH162_RS06095	COG5002	protein histidine kinase activity
EH162_RS06095	COG3850	Histidine kinase
EH162_RS06100	COG0745	RESPONSE REGULATOR receiver
EH162_RS06105	COG0577	efflux transmembrane transporter activity
EH162_RS06110	COG1136	(ABC) transporter
EH162_RS06125	COG4640	response to antibiotic
EH162_RS06130	COG2814	Major facilitator Superfamily
EH162_RS06140	COG1566	PFAM secretion protein HlyD family protein
EH162_RS06145	COG2814	Major facilitator Superfamily
EH162_RS06160	COG0657	acetylesterase activity
EH162_RS06175	COG0598	Magnesium transport protein CorA
EH162_RS06180	COG1304	FMN binding
EH162_RS06185	COG0786	glutamate:sodium symporter activity
EH162_RS06205	COG2094	Belongs to the DNA glycosylase MPG family
EH162_RS06230	COG1069	ribulokinase activity
EH162_RS06235	COG2017	converts alpha-aldose to the beta-anomer
EH162_RS06240	COG2258	MOSC domain
EH162_RS06245	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EH162_RS06260	COG1266	CAAX protease self-immunity
EH162_RS06265	COG0010	Belongs to the arginase family
EH162_RS06270	COG1473	amidohydrolase
EH162_RS06275	COG1028	Short-chain dehydrogenase reductase Sdr
EH162_RS06280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH162_RS06300	COG1737	Transcriptional regulator
EH162_RS06305	COG1263	PTS System
EH162_RS06305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH162_RS06315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH162_RS06340	COG1113	amino acid transport
EH162_RS06350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH162_RS06350	COG1263	PTS System
EH162_RS06355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EH162_RS06370	COG1266	CAAX protease self-immunity
EH162_RS06375	COG2378	regulation of single-species biofilm formation
EH162_RS06380	COG0483	inositol monophosphate 1-phosphatase activity
EH162_RS06385	COG1316	TRANSCRIPTIONal
EH162_RS06410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH162_RS06415	COG2076	Multidrug Resistance protein
EH162_RS06420	COG2076	Multidrug Resistance protein
EH162_RS06425	COG3942	CHAP domain
EH162_RS06440	COG1757	Na H antiporter
EH162_RS06445	COG3942	CHAP domain
EH162_RS06470	COG0829	nickel cation binding
EH162_RS06475	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EH162_RS06480	COG0830	nickel cation binding
EH162_RS06485	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EH162_RS06490	COG0804	urea catabolic process
EH162_RS06495	COG0832	Belongs to the urease beta subunit family
EH162_RS06500	COG0831	urea catabolic process
EH162_RS06515	COG1960	acyl-CoA dehydrogenase activity
EH162_RS06520	COG1957	nucleoside hydrolase
EH162_RS06525	COG1268	BioY protein
EH162_RS06535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EH162_RS06545	COG0725	ABC transporter, periplasmic molybdate-binding protein
EH162_RS06550	COG4149	molybdate abc transporter
EH162_RS06555	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EH162_RS06560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EH162_RS06565	COG0521	Mo-molybdopterin cofactor biosynthetic process
EH162_RS06570	COG0315	cyclic pyranopterin monophosphate synthase activity
EH162_RS06575	COG0303	'Molybdopterin
EH162_RS06585	COG0314	molybdopterin synthase activity
EH162_RS06595	COG0746	molybdenum cofactor guanylyltransferase activity
EH162_RS06600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EH162_RS06625	COG2814	Major facilitator Superfamily
EH162_RS06640	COG2348	transferase activity, transferring amino-acyl groups
EH162_RS06645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH162_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
EH162_RS06670	COG4975	Glucose uptake
EH162_RS06675	COG0551	DNA topoisomerase type I activity
EH162_RS06675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH162_RS06680	COG2252	PERMEase
EH162_RS06695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EH162_RS06700	COG0088	Forms part of the polypeptide exit tunnel
EH162_RS06705	COG0089	rRNA binding
EH162_RS06710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EH162_RS06715	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EH162_RS06720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EH162_RS06725	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EH162_RS06730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EH162_RS06740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EH162_RS06745	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EH162_RS06750	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EH162_RS06755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EH162_RS06760	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EH162_RS06765	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EH162_RS06770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EH162_RS06775	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EH162_RS06780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EH162_RS06785	COG1841	ribosomal large subunit assembly
EH162_RS06790	COG0200	Binds to the 23S rRNA
EH162_RS06795	COG0201	protein transport
EH162_RS06800	COG0563	adenylate kinase activity
EH162_RS06805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EH162_RS06810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EH162_RS06815	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EH162_RS06820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EH162_RS06825	COG0202	RNA polymerase activity
EH162_RS06830	COG0203	ribosomal protein L17
EH162_RS06835	COG1122	ATPase activity
EH162_RS06840	COG1122	ATPase activity
EH162_RS06850	COG0101	tRNA pseudouridine synthase activity
EH162_RS06855	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EH162_RS06860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EH162_RS06865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EH162_RS06870	COG1349	DNA-binding transcription factor activity
EH162_RS06875	COG0698	ribose 5-phosphate isomerase
EH162_RS06880	COG0698	ribose 5-phosphate isomerase
EH162_RS06885	COG1105	Belongs to the carbohydrate kinase PfkB family
EH162_RS06890	COG3684	Belongs to the aldolase LacD family
EH162_RS06895	COG1447	Phosphotransferase system cellobiose-specific component IIA
EH162_RS06900	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH162_RS06900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EH162_RS06905	COG2723	6-phospho-beta-galactosidase activity
EH162_RS06915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH162_RS06920	COG2130	NADP-dependent
EH162_RS06925	COG0604	alcohol dehydrogenase
EH162_RS06940	COG1302	Protein conserved in bacteria
EH162_RS06945	COG4264	IucA IucC family
EH162_RS06950	COG2814	Major facilitator Superfamily
EH162_RS06955	COG4264	IucA IucC family
EH162_RS06960	COG3457	Alanine racemase
EH162_RS06965	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EH162_RS06970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH162_RS06975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH162_RS06980	COG3314	Sporulation integral membrane protein YlbJ
EH162_RS06985	COG2329	Antibiotic biosynthesis monooxygenase
EH162_RS06995	COG1988	membrane-bound metal-dependent
EH162_RS07000	COG4284	Utp--glucose-1-phosphate uridylyltransferase
EH162_RS07020	COG2814	Major facilitator Superfamily
EH162_RS07025	COG0489	protein tyrosine kinase activity
EH162_RS07075	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EH162_RS07085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EH162_RS07090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EH162_RS07095	COG0561	phosphatase activity
EH162_RS07115	COG0640	Transcriptional regulator
EH162_RS07120	COG0702	epimerase
EH162_RS07130	COG1482	cell wall glycoprotein biosynthetic process
EH162_RS07155	COG0783	Belongs to the Dps family
EH162_RS07160	COG0813	purine-nucleoside phosphorylase activity
EH162_RS07165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EH162_RS07170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EH162_RS07175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EH162_RS07185	COG1854	S-ribosylhomocysteine lyase activity
EH162_RS07205	COG5146	pantothenate kinase activity
EH162_RS07215	COG3343	RNA polymerase activity
EH162_RS07220	COG0504	CTP synthase activity
EH162_RS07230	COG0191	fructose-bisphosphate aldolase activity
EH162_RS07235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EH162_RS07245	COG1012	belongs to the aldehyde dehydrogenase family
EH162_RS07250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EH162_RS07255	COG0254	rRNA binding
EH162_RS07265	COG1435	thymidine kinase activity
EH162_RS07270	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EH162_RS07275	COG2890	protein-(glutamine-N5) methyltransferase activity
EH162_RS07285	COG0009	L-threonylcarbamoyladenylate synthase
EH162_RS07290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EH162_RS07295	COG4475	Protein of unknown function (DUF436)
EH162_RS07300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EH162_RS07305	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EH162_RS07310	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EH162_RS07320	COG0356	it plays a direct role in the translocation of protons across the membrane
EH162_RS07330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EH162_RS07335	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EH162_RS07340	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EH162_RS07345	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EH162_RS07350	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EH162_RS07355	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EH162_RS07365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EH162_RS07370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EH162_RS07380	COG0629	single-stranded DNA binding
EH162_RS07385	COG1388	LysM domain
EH162_RS07390	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EH162_RS07400	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EH162_RS07405	COG0352	thiamine-phosphate diphosphorylase activity
EH162_RS07410	COG0706	membrane insertase activity
EH162_RS07415	COG1418	mRNA catabolic process
EH162_RS07420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH162_RS07425	COG1937	Protein conserved in bacteria
EH162_RS07440	COG0772	Belongs to the SEDS family
EH162_RS07445	COG1181	Belongs to the D-alanine--D-alanine ligase family
EH162_RS07450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EH162_RS07455	COG0513	Belongs to the DEAD box helicase family
EH162_RS07465	COG3428	Bacterial PH domain
EH162_RS07470	COG3402	PFAM membrane-flanked domain
EH162_RS07475	COG0736	holo-[acyl-carrier-protein] synthase activity
EH162_RS07480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EH162_RS07490	COG2337	Toxic component of a toxin-antitoxin (TA) module
EH162_RS07495	COG2208	phosphoserine phosphatase activity
EH162_RS07510	COG1191	sigma factor activity
EH162_RS07515	COG2183	response to ionizing radiation
EH162_RS07520	COG3091	SprT-like family
EH162_RS07560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EH162_RS07565	COG0066	3-isopropylmalate dehydratase activity
EH162_RS07570	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EH162_RS07575	COG0473	3-isopropylmalate dehydrogenase activity
EH162_RS07580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH162_RS07585	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EH162_RS07595	COG0028	Belongs to the TPP enzyme family
EH162_RS07600	COG0129	dihydroxy-acid dehydratase activity
EH162_RS07605	COG0802	atpase or kinase
EH162_RS07610	COG1214	PFAM Peptidase M22, glycoprotease
EH162_RS07615	COG0456	acetyltransferase
EH162_RS07620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EH162_RS07625	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EH162_RS07630	COG0488	(ABC) transporter
EH162_RS07635	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EH162_RS07645	COG2391	methyltransferase activity
EH162_RS07650	COG0425	Belongs to the sulfur carrier protein TusA family
EH162_RS07655	COG0004	ammonium transporteR
EH162_RS07660	COG1609	Transcriptional regulator
EH162_RS07670	COG1621	beta-fructofuranosidase activity
EH162_RS07675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH162_RS07680	COG3279	Response regulator of the LytR AlgR family
EH162_RS07720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EH162_RS07725	COG0459	protein refolding
EH162_RS07745	COG1725	Transcriptional regulator
EH162_RS07750	COG1131	(ABC) transporter
EH162_RS07760	COG1131	(ABC) transporter
EH162_RS07840	COG3682	Transcriptional regulator
EH162_RS07850	COG2706	6-phosphogluconolactonase activity
EH162_RS07855	COG1012	belongs to the aldehyde dehydrogenase family
EH162_RS07860	COG1227	inorganic diphosphatase activity
EH162_RS07865	COG1335	isochorismatase
EH162_RS07875	COG0077	Prephenate dehydratase
EH162_RS07885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EH162_RS07890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EH162_RS07895	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EH162_RS07905	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EH162_RS07910	COG4496	protein, YerC YecD
EH162_RS07915	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EH162_RS07920	COG0210	DNA helicase
EH162_RS07925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EH162_RS07930	COG4851	CamS sex pheromone cAM373 precursor
EH162_RS07935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EH162_RS07940	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EH162_RS07945	COG0154	amidase activity
EH162_RS07950	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EH162_RS07955	COG1597	lipid kinase activity
EH162_RS07960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH162_RS07970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EH162_RS07980	COG1528	Iron-storage protein
EH162_RS08000	COG4129	membrane
EH162_RS08005	COG0024	Methionine aminopeptidase
EH162_RS08020	COG4585	Histidine kinase
EH162_RS08025	COG2197	response regulator
EH162_RS08030	COG1295	ribonuclease BN
EH162_RS08040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EH162_RS08045	COG4840	Belongs to the UPF0435 family
EH162_RS08050	COG2309	aminopeptidase activity
EH162_RS08055	COG1607	acyl-coa hydrolase
EH162_RS08060	COG0535	radical SAM domain protein
EH162_RS08070	COG0693	protein deglycase activity
EH162_RS08075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EH162_RS08080	COG2137	regulation of response to DNA damage stimulus
EH162_RS08090	COG1388	LysM domain
EH162_RS08090	COG1134	teichoic acid transport
EH162_RS08100	COG1988	membrane-bound metal-dependent
EH162_RS08110	COG3557	Belongs to the UPF0374 family
EH162_RS08120	COG4129	membrane
EH162_RS08125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EH162_RS08130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH162_RS08135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH162_RS08140	COG0735	belongs to the Fur family
EH162_RS08305	COG0765	amino acid transport
EH162_RS08310	COG1126	abc transporter atp-binding protein
EH162_RS08315	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EH162_RS08340	COG0114	fumarate hydratase activity
EH162_RS08345	COG0564	pseudouridine synthase activity
EH162_RS08350	COG2203	Gaf domain
EH162_RS08350	COG4585	Histidine kinase
EH162_RS08355	COG2197	response regulator
EH162_RS08370	COG4399	Belongs to the UPF0754 family
EH162_RS08375	COG3679	Belongs to the UPF0342 family
EH162_RS08380	COG0420	3'-5' exonuclease activity
EH162_RS08390	COG3481	metal-dependent phosphohydrolase, HD sub domain
EH162_RS08400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH162_RS08415	COG0537	adenosine 5'-monophosphoramidase activity
EH162_RS08420	COG1131	(ABC) transporter
EH162_RS08425	COG4473	ABC transporter
EH162_RS08435	COG2329	Antibiotic biosynthesis monooxygenase
EH162_RS08440	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EH162_RS08445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH162_RS08450	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EH162_RS08550	COG0318	PFAM AMP-dependent synthetase and ligase
EH162_RS08560	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EH162_RS08565	COG0494	nUDIX hydrolase
EH162_RS08570	COG1506	peptidase
EH162_RS08575	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EH162_RS08580	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EH162_RS08590	COG0656	L-ascorbic acid biosynthetic process
EH162_RS08595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EH162_RS08600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EH162_RS08610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH162_RS08640	COG5632	N-Acetylmuramoyl-L-alanine amidase
EH162_RS08640	COG4193	domain, Protein
EH162_RS08640	COG3266	domain, Protein
EH162_RS08650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH162_RS08650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH162_RS08660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH162_RS08660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH162_RS08665	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EH162_RS08675	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EH162_RS08680	COG1242	4 iron, 4 sulfur cluster binding
EH162_RS08685	COG2814	Major facilitator Superfamily
EH162_RS08690	COG0495	leucyl-tRNA aminoacylation
EH162_RS08705	COG2081	HI0933 family
EH162_RS08710	COG2244	polysaccharide biosynthetic process
EH162_RS08715	COG1187	pseudouridine synthase activity
EH162_RS08725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EH162_RS08730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EH162_RS08735	COG0510	thiamine kinase activity
EH162_RS08740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EH162_RS08750	COG1363	Peptidase, m42
EH162_RS08755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH162_RS08760	COG4848	Belongs to the UPF0354 family
EH162_RS08765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH162_RS08770	COG1674	ftsk spoiiie
EH162_RS08775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EH162_RS08780	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EH162_RS08790	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EH162_RS08790	COG1605	Chorismate mutase
EH162_RS08795	COG1609	Transcriptional regulator
EH162_RS08800	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EH162_RS08810	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EH162_RS08815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH162_RS08820	COG0204	Acyl-transferase
EH162_RS08825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EH162_RS08825	COG1263	PTS System
EH162_RS08835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH162_RS08840	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EH162_RS08845	COG1764	response to oxidative stress
EH162_RS08850	COG0584	glycerophosphoryl diester phosphodiesterase
EH162_RS08855	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EH162_RS08865	COG1956	GAF domain-containing protein
EH162_RS08870	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EH162_RS08880	COG0301	tRNA thio-modification
EH162_RS08890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EH162_RS08895	COG0827	DNA restriction-modification system
EH162_RS08900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EH162_RS08905	COG0589	response to stress
EH162_RS08910	COG0686	Belongs to the AlaDH PNT family
EH162_RS08915	COG0006	proline dipeptidase activity
EH162_RS08920	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EH162_RS08930	COG4109	DRTGG domain
EH162_RS08935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EH162_RS08940	COG0587	DNA-directed DNA polymerase activity
EH162_RS08945	COG0281	malic enzyme
EH162_RS08950	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EH162_RS08955	COG0825	malonyl-CoA metabolic process
EH162_RS08960	COG0205	6-phosphofructokinase activity
EH162_RS08965	COG0469	pyruvate kinase activity
EH162_RS08970	COG1113	amino acid transport
EH162_RS08975	COG0372	Belongs to the citrate synthase family
EH162_RS08980	COG0538	isocitrate dehydrogenase activity
EH162_RS08985	COG0745	RESPONSE REGULATOR receiver
EH162_RS08990	COG5002	protein histidine kinase activity
EH162_RS08995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH162_RS08995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH162_RS09000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EH162_RS09005	COG0237	dephospho-CoA kinase activity
EH162_RS09015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EH162_RS09020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EH162_RS09025	COG3611	Membrane attachment protein
EH162_RS09030	COG1484	DNA-dependent DNA replication
EH162_RS09035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EH162_RS09040	COG0833	amino acid
EH162_RS09045	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EH162_RS09050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EH162_RS09055	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EH162_RS09060	COG4112	unkown
EH162_RS09070	COG0544	peptidyl-prolyl cis-trans isomerase activity
EH162_RS09075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EH162_RS09080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EH162_RS09085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EH162_RS09095	COG0181	hydroxymethylbilane synthase activity
EH162_RS09105	COG0113	porphobilinogen synthase activity
EH162_RS09110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EH162_RS09120	COG2818	Glycosylase
EH162_RS09125	COG0525	valine-tRNA ligase activity
EH162_RS09130	COG0285	dihydrofolate synthase activity
EH162_RS09140	COG2003	Belongs to the UPF0758 family
EH162_RS09170	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EH162_RS09175	COG2868	ribosomal protein
EH162_RS09180	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EH162_RS09185	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EH162_RS09190	COG4492	Belongs to the UPF0735 family
EH162_RS09195	COG0632	four-way junction helicase activity
EH162_RS09200	COG2255	four-way junction helicase activity
EH162_RS09205	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EH162_RS09210	COG0343	queuine tRNA-ribosyltransferase activity
EH162_RS09215	COG1862	Preprotein translocase
EH162_RS09220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH162_RS09220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH162_RS09225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EH162_RS09225	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EH162_RS09230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EH162_RS09240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EH162_RS09245	COG1490	D-aminoacyl-tRNA deacylase activity
EH162_RS09250	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH162_RS09255	COG0124	histidyl-tRNA synthetase
EH162_RS09260	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EH162_RS09270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EH162_RS09275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EH162_RS09280	COG1959	2 iron, 2 sulfur cluster binding
EH162_RS09290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH162_RS09295	COG1104	cysteine desulfurase activity
EH162_RS09300	COG0482	sulfurtransferase activity
EH162_RS09310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EH162_RS09315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EH162_RS09320	COG4472	Bacterial protein of unknown function (DUF965)
EH162_RS09325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EH162_RS09330	COG3906	Belongs to the UPF0473 family
EH162_RS09340	COG0826	peptidase U32
EH162_RS09345	COG0826	peptidase U32
EH162_RS09350	COG0572	uridine kinase
EH162_RS09355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EH162_RS09365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EH162_RS09370	COG1984	allophanate hydrolase subunit 2
EH162_RS09375	COG0511	ligase activity, forming carbon-carbon bonds
EH162_RS09380	COG0439	Biotin carboxylase
EH162_RS09385	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EH162_RS09390	COG1914	H( )-stimulated, divalent metal cation uptake system
EH162_RS09395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EH162_RS09400	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EH162_RS09405	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EH162_RS09410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EH162_RS09415	COG1534	Rna-binding protein
EH162_RS09420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EH162_RS09425	COG1713	HD superfamily hydrolase involved in NAD metabolism
EH162_RS09430	COG0799	negative regulation of ribosome biogenesis
EH162_RS09435	COG2226	methyltransferase
EH162_RS09445	COG2131	deaminase
EH162_RS09450	COG2333	competence protein COMEC
EH162_RS09450	COG0658	competence protein
EH162_RS09455	COG1466	dna polymerase III delta subunit
EH162_RS09465	COG0268	Binds directly to 16S ribosomal RNA
EH162_RS09470	COG0481	GTPase activity
EH162_RS09475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH162_RS09480	COG1420	regulation of RNA biosynthetic process
EH162_RS09485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EH162_RS09490	COG0443	Heat shock 70 kDa protein
EH162_RS09495	COG0484	heat shock protein binding
EH162_RS09500	COG2264	protein methyltransferase activity
EH162_RS09505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EH162_RS09510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH162_RS09520	COG1030	water channel activity
EH162_RS09525	COG4864	UPF0365 protein
EH162_RS09535	COG1702	phosphate starvation-inducible protein PhoH
EH162_RS09540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EH162_RS09545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EH162_RS09550	COG0295	cytidine deaminase activity
EH162_RS09555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EH162_RS09560	COG1381	Involved in DNA repair and RecF pathway recombination
EH162_RS09565	COG0423	glycine-tRNA ligase activity
EH162_RS09570	COG0517	IMP dehydrogenase activity
EH162_RS09575	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EH162_RS09580	COG0358	DNA primase activity
EH162_RS09585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH162_RS09590	COG2384	SAM-dependent methyltransferase
EH162_RS09595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EH162_RS09600	COG0513	Belongs to the DEAD box helicase family
EH162_RS09605	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EH162_RS09610	COG1121	(ABC) transporter
EH162_RS09615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH162_RS09620	COG0735	belongs to the Fur family
EH162_RS09625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EH162_RS09640	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EH162_RS09645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EH162_RS09655	COG4483	Protein conserved in bacteria
EH162_RS09660	COG1940	carbohydrate kinase activity
EH162_RS09665	COG0011	TIGRFAM Protein of
EH162_RS09675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EH162_RS09680	COG1459	type II secretion system
EH162_RS09685	COG4537	Required for transformation and DNA binding
EH162_RS09710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EH162_RS09715	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EH162_RS09720	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EH162_RS09725	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EH162_RS09735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH162_RS09740	COG0095	Lipoate-protein ligase
EH162_RS09755	COG0006	proline dipeptidase activity
EH162_RS09760	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EH162_RS09765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EH162_RS09770	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EH162_RS09775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EH162_RS09780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH162_RS09785	COG0511	ligase activity, forming carbon-carbon bonds
EH162_RS09790	COG0439	Biotin carboxylase
EH162_RS09795	COG1302	Protein conserved in bacteria
EH162_RS09800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH162_RS09805	COG1570	exodeoxyribonuclease VII activity
EH162_RS09810	COG1722	exodeoxyribonuclease VII activity
EH162_RS09820	COG1438	arginine binding
EH162_RS09825	COG0497	DNA recombination
EH162_RS09830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH162_RS09835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EH162_RS09840	COG0022	dehydrogenase e1 component
EH162_RS09845	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH162_RS09855	COG4129	membrane
EH162_RS09860	COG2195	Cleaves the N-terminal amino acid of tripeptides
EH162_RS09865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EH162_RS09870	COG0366	Alpha amylase catalytic
EH162_RS09885	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EH162_RS09890	COG1234	tRNA 3'-trailer cleavage
EH162_RS09895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EH162_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
EH162_RS09905	COG0667	Aldo Keto reductase
EH162_RS09910	COG0494	nUDIX hydrolase
EH162_RS09915	COG0735	belongs to the Fur family
EH162_RS09920	COG4974	Belongs to the 'phage' integrase family
EH162_RS09925	COG1547	Domain of unknown function (DUF309)
EH162_RS09930	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EH162_RS09935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EH162_RS09940	COG1187	pseudouridine synthase activity
EH162_RS09945	COG0745	RESPONSE REGULATOR receiver
EH162_RS09965	COG1141	Ferredoxin
EH162_RS09975	COG0514	ATP-dependent DNA helicase (RecQ)
EH162_RS09980	COG1388	LysM domain
EH162_RS09985	COG0492	ferredoxin-NADP+ reductase activity
EH162_RS09990	COG0252	asparaginase activity
EH162_RS09995	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EH162_RS10000	COG0539	negative regulation of cytoplasmic translation
EH162_RS10005	COG1160	GTP binding
EH162_RS10010	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EH162_RS10025	COG2226	methyltransferase
EH162_RS10035	COG0105	UTP biosynthetic process
EH162_RS10040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EH162_RS10045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EH162_RS10050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EH162_RS10060	COG5582	Belongs to the UPF0302 family
EH162_RS10065	COG4347	Protein of unknown function (DUF1405)
EH162_RS10070	COG2738	Putative neutral zinc metallopeptidase
EH162_RS10075	COG1694	Mazg nucleotide pyrophosphohydrolase
EH162_RS10080	COG0438	transferase activity, transferring glycosyl groups
EH162_RS10085	COG0617	tRNA 3'-terminal CCA addition
EH162_RS10090	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EH162_RS10090	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EH162_RS10095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EH162_RS10095	COG1199	ATP-dependent helicase activity
EH162_RS10100	COG0017	Asparaginyl-tRNA synthetase
EH162_RS10105	COG3935	DnaD domain protein
EH162_RS10110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EH162_RS10120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EH162_RS10120	COG4499	WXG100 protein secretion system (Wss), protein YukC
EH162_RS10125	COG3331	DNA recombination
EH162_RS10135	COG4474	Belongs to the UPF0398 family
EH162_RS10140	COG3599	regulation of cell shape
EH162_RS10150	COG0116	Belongs to the methyltransferase superfamily
EH162_RS10160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EH162_RS10165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH162_RS10170	COG1196	nuclear chromosome segregation
EH162_RS10170	COG4372	Transposase
EH162_RS10170	COG1511	domain protein
EH162_RS10180	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EH162_RS10190	COG1413	lyase activity
EH162_RS10205	COG1136	(ABC) transporter
EH162_RS10230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH162_RS10235	COG2190	(PTS) system
EH162_RS10240	COG4479	Belongs to the UPF0346 family
EH162_RS10245	COG0793	Belongs to the peptidase S41A family
EH162_RS10260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EH162_RS10265	COG0671	phosphoesterase, PA-phosphatase related
EH162_RS10280	COG0745	RESPONSE REGULATOR receiver
EH162_RS10285	COG5002	protein histidine kinase activity
EH162_RS10295	COG0567	Dehydrogenase, E1 component
EH162_RS10300	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH162_RS10320	COG0714	Associated with various cellular activities
EH162_RS10325	COG4548	von Willebrand factor, type A
EH162_RS10330	COG1114	Component of the transport system for branched-chain amino acids
EH162_RS10335	COG3853	Toxic anion resistance protein (TelA)
EH162_RS10345	COG1254	Belongs to the acylphosphatase family
EH162_RS10355	COG1278	Cold shock
EH162_RS10380	COG1131	(ABC) transporter
EH162_RS10405	COG1473	amidohydrolase
EH162_RS10410	COG2171	N-acyltransferase activity
EH162_RS10415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EH162_RS10420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH162_RS10425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EH162_RS10430	COG0527	aspartate kinase activity
EH162_RS10435	COG0488	(ABC) transporter
EH162_RS10440	COG2996	Protein conserved in bacteria
EH162_RS10445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH162_RS10450	COG0573	inorganic phosphate transmembrane transporter activity
EH162_RS10455	COG0581	inorganic phosphate transmembrane transporter activity
EH162_RS10460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH162_RS10465	COG0704	Plays a role in the regulation of phosphate uptake
EH162_RS10505	COG2348	transferase activity, transferring amino-acyl groups
EH162_RS10510	COG2348	transferase activity, transferring amino-acyl groups
EH162_RS10525	COG0159	tryptophan synthase activity
EH162_RS10530	COG0133	tryptophan synthase activity
EH162_RS10535	COG0135	phosphoribosylanthranilate isomerase activity
EH162_RS10540	COG0134	indole-3-glycerol-phosphate synthase activity
EH162_RS10545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH162_RS10550	COG0512	Glutamine amidotransferase of anthranilate synthase
EH162_RS10550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH162_RS10555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EH162_RS10560	COG0287	Prephenate dehydrogenase
EH162_RS10565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EH162_RS10570	COG1942	4-Oxalocrotonate Tautomerase
EH162_RS10590	COG0392	lysyltransferase activity
EH162_RS10590	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EH162_RS10595	COG0628	permease
EH162_RS10600	COG3711	transcriptional antiterminator
EH162_RS10605	COG1115	amino acid carrier protein
EH162_RS10610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EH162_RS10615	COG0187	DNA topoisomerase II activity
EH162_RS10620	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EH162_RS10625	COG4841	protein insertion into membrane
EH162_RS10630	COG0824	Thioesterase
EH162_RS10635	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EH162_RS10640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EH162_RS10645	COG1970	mechanosensitive ion channel activity
EH162_RS10650	COG0419	ATPase involved in DNA repair
EH162_RS10655	COG0420	3'-5' exonuclease activity
EH162_RS10660	COG4846	Membrane protein involved in cytochrome C biogenesis
EH162_RS10670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EH162_RS10675	COG4224	UPF0291 protein
EH162_RS10685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EH162_RS10690	COG2340	Cysteine-rich secretory protein family
EH162_RS10695	COG0516	GMP reductase activity
EH162_RS10700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EH162_RS10710	COG0753	catalase activity
EH162_RS10715	COG0833	amino acid
EH162_RS10730	COG0083	homoserine kinase activity
EH162_RS10735	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EH162_RS10740	COG0460	homoserine dehydrogenase
EH162_RS10745	COG0527	aspartate kinase activity
EH162_RS10770	COG1525	nuclease
EH162_RS10785	COG2197	response regulator
EH162_RS10790	COG4585	Histidine kinase
EH162_RS10800	COG1131	(ABC) transporter
EH162_RS10805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH162_RS10850	COG0174	glutamine synthetase
EH162_RS10855	COG0789	Transcriptional regulator
EH162_RS10860	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EH162_RS10865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EH162_RS10870	COG0386	Belongs to the glutathione peroxidase family
EH162_RS10875	COG1923	regulation of RNA biosynthetic process
EH162_RS10880	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EH162_RS10890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EH162_RS10895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EH162_RS10900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EH162_RS10905	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EH162_RS10910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EH162_RS10915	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EH162_RS10925	COG4550	Control of competence regulator ComK, YlbF/YmcA
EH162_RS10930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH162_RS10940	COG4195	phage-related replication protein
EH162_RS10945	COG1013	pyruvate-flavodoxin oxidoreductase activity
EH162_RS10950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EH162_RS10950	COG0674	pyruvate-flavodoxin oxidoreductase activity
EH162_RS10955	COG1692	metallophosphoesterase
EH162_RS10965	COG1418	mRNA catabolic process
EH162_RS10970	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EH162_RS10975	COG1546	Belongs to the CinA family
EH162_RS10975	COG1058	Belongs to the CinA family
EH162_RS10980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EH162_RS10995	COG0300	oxidoreductase activity
EH162_RS11000	COG0612	Peptidase, M16
EH162_RS11005	COG0612	Peptidase, M16
EH162_RS11010	COG2188	Transcriptional regulator
EH162_RS11015	COG1674	ftsk spoiiie
EH162_RS11020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EH162_RS11025	COG1185	polyribonucleotide nucleotidyltransferase activity
EH162_RS11030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EH162_RS11035	COG0196	riboflavin kinase activity
EH162_RS11040	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EH162_RS11045	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EH162_RS11050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EH162_RS11055	COG1358	cellular component organization or biogenesis
EH162_RS11060	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EH162_RS11065	COG0195	Participates in both transcription termination and antitermination
EH162_RS11070	COG0779	Required for maturation of 30S ribosomal subunits
EH162_RS11075	COG2176	DNA-directed DNA polymerase activity
EH162_RS11080	COG0442	prolyl-tRNA aminoacylation
EH162_RS11090	COG4589	Belongs to the CDS family
EH162_RS11095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EH162_RS11100	COG0233	cytoplasmic translational termination
EH162_RS11105	COG0528	UMP kinase activity
EH162_RS11110	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EH162_RS11115	COG0052	Belongs to the universal ribosomal protein uS2 family
EH162_RS11120	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EH162_RS11125	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EH162_RS11130	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EH162_RS11135	COG4974	Belongs to the 'phage' integrase family
EH162_RS11140	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EH162_RS11145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH162_RS11150	COG0758	DNA mediated transformation
EH162_RS11155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EH162_RS11160	COG0045	succinate-CoA ligase (ADP-forming) activity
EH162_RS11165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EH162_RS11180	COG4485	Bacterial membrane protein, YfhO
EH162_RS11190	COG0335	large ribosomal subunit rRNA binding
EH162_RS11195	COG0336	Belongs to the RNA methyltransferase TrmD family
EH162_RS11200	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EH162_RS11205	COG0228	four-way junction DNA binding
EH162_RS11210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EH162_RS11215	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EH162_RS11220	COG0552	protein localization to endoplasmic reticulum
EH162_RS11225	COG1196	nuclear chromosome segregation
EH162_RS11230	COG0571	ribonuclease III activity
EH162_RS11235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH162_RS11240	COG1028	Short-chain dehydrogenase reductase Sdr
EH162_RS11250	COG0416	fatty acid biosynthetic process
EH162_RS11255	COG1349	DNA-binding transcription factor activity
EH162_RS11260	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EH162_RS11265	COG1461	Dihydroxyacetone kinase
EH162_RS11270	COG1302	Protein conserved in bacteria
EH162_RS11275	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EH162_RS11285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EH162_RS11290	COG1162	GTPase activity
EH162_RS11300	COG0631	protein serine/threonine phosphatase activity
EH162_RS11305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EH162_RS11310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH162_RS11310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH162_RS11315	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EH162_RS11320	COG0242	peptide deformylase activity
EH162_RS11330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EH162_RS11335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EH162_RS11340	COG1758	RNA polymerase activity
EH162_RS11345	COG0194	GDP metabolic process
EH162_RS11365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EH162_RS11370	COG0284	orotidine-5'-phosphate decarboxylase activity
EH162_RS11375	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EH162_RS11380	COG0505	Belongs to the CarA family
EH162_RS11385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EH162_RS11390	COG0540	Belongs to the ATCase OTCase family
EH162_RS11395	COG2233	PERMEase
EH162_RS11400	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EH162_RS11405	COG0564	pseudouridine synthase activity
EH162_RS11410	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EH162_RS11415	COG3942	CHAP domain
EH162_RS11415	COG1388	LysM domain
EH162_RS11425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EH162_RS11430	COG3599	regulation of cell shape
EH162_RS11440	COG0762	integral membrane protein
EH162_RS11445	COG1799	cell septum assembly
EH162_RS11450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EH162_RS11455	COG1496	oxidoreductase activity
EH162_RS11475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EH162_RS11480	COG0849	cell division
EH162_RS11485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EH162_RS11490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EH162_RS11495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH162_RS11500	COG0768	penicillin binding
EH162_RS11505	COG4839	cell division protein FtsL
EH162_RS11510	COG0275	rRNA processing
EH162_RS11515	COG2001	Belongs to the MraZ family
EH162_RS11520	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EH162_RS11525	COG0454	-acetyltransferase
EH162_RS11530	COG1011	Hydrolase
EH162_RS11565	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EH162_RS11570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EH162_RS11575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EH162_RS11580	COG1053	succinate dehydrogenase
EH162_RS11585	COG2009	succinate dehydrogenase
EH162_RS11595	COG0322	excinuclease ABC activity
EH162_RS11600	COG3118	belongs to the thioredoxin family
EH162_RS11605	COG1193	negative regulation of DNA recombination
EH162_RS11610	COG1796	DNA polymerase
EH162_RS11610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EH162_RS11620	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EH162_RS11625	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EH162_RS11630	COG0072	phenylalanine-tRNA ligase activity
EH162_RS11630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH162_RS11635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EH162_RS11640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH162_RS11650	COG3583	domain protein
EH162_RS11650	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EH162_RS11650	COG4932	domain protein
EH162_RS11655	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EH162_RS11670	COG1323	Belongs to the UPF0348 family
EH162_RS11675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EH162_RS11680	COG0742	ribosomal rna small subunit methyltransferase
EH162_RS11690	COG4471	UPF0298 protein
EH162_RS11700	COG0584	glycerophosphoryl diester phosphodiesterase
EH162_RS11705	COG3679	Belongs to the UPF0342 family
EH162_RS11710	COG2340	Cysteine-rich secretory protein family
EH162_RS11720	COG0109	protoheme IX farnesyltransferase activity
EH162_RS11725	COG1612	heme a metabolic process
EH162_RS11735	COG0772	Belongs to the SEDS family
EH162_RS11740	COG4838	Belongs to the UPF0358 family
EH162_RS11745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EH162_RS11750	COG4896	Protein conserved in bacteria
EH162_RS11765	COG1217	gtp-binding protein TYPA
EH162_RS11775	COG0483	inositol monophosphate 1-phosphatase activity
EH162_RS11780	COG4493	Belongs to the UPF0637 family
EH162_RS11785	COG1914	H( )-stimulated, divalent metal cation uptake system
EH162_RS11810	COG1176	ABC-type spermidine putrescine transport system, permease component I
EH162_RS11815	COG3842	ATPase activity
EH162_RS11825	COG4476	Belongs to the UPF0223 family
EH162_RS11835	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH162_RS11840	COG0022	dehydrogenase e1 component
EH162_RS11845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EH162_RS11855	COG0242	peptide deformylase activity
EH162_RS11860	COG5503	Protein of unknown function (DUF1447)
EH162_RS11865	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EH162_RS11870	COG0569	domain protein
EH162_RS11875	COG1294	oxidase, subunit
EH162_RS11880	COG1271	oxidase subunit
EH162_RS11890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH162_RS11895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EH162_RS11905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EH162_RS11920	COG4716	Myosin-crossreactive antigen
EH162_RS11930	COG4172	Belongs to the ABC transporter superfamily
EH162_RS11935	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EH162_RS11940	COG0151	Belongs to the GarS family
EH162_RS11945	COG0138	bifunctional purine biosynthesis protein purh
EH162_RS11950	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EH162_RS11955	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EH162_RS11960	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EH162_RS11965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EH162_RS11970	COG0047	phosphoribosylformylglycinamidine synthase activity
EH162_RS11975	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EH162_RS11980	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EH162_RS11985	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EH162_RS11990	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EH162_RS11995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EH162_RS12005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH162_RS12010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EH162_RS12015	COG1845	cytochrome c oxidase, subunit III
EH162_RS12020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EH162_RS12045	COG1316	TRANSCRIPTIONal
EH162_RS12070	COG3594	Acyltransferase
EH162_RS12075	COG0436	Aminotransferase
EH162_RS12080	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EH162_RS12090	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EH162_RS12095	COG1169	isochorismate synthase
EH162_RS12105	COG1575	Belongs to the MenA family. Type 1 subfamily
EH162_RS12115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH162_RS12125	COG2314	TM2 domain
EH162_RS12170	COG5632	N-Acetylmuramoyl-L-alanine amidase
EH162_RS12170	COG1388	LysM domain
EH162_RS12195	COG4195	phage-related replication protein
EH162_RS12275	COG1686	Belongs to the peptidase S11 family
EH162_RS12380	COG3764	Sortase (surface protein transpeptidase)
EH162_RS12425	COG1388	LysM domain
EH162_RS12425	COG3942	CHAP domain
EH162_RS12480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EH162_RS12510	COG0456	acetyltransferase
EH162_RS12645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EH162_RS12730	COG0577	efflux transmembrane transporter activity
EH162_RS12730	COG1136	(ABC) transporter