locus-tag	class	description
EGX64_RS00015	COG2217	Heavy metal translocating P-type atpase
EGX64_RS00020	COG1937	Protein conserved in bacteria
EGX64_RS00030	COG1230	cation diffusion facilitator family transporter
EGX64_RS00050	COG0456	acetyltransferase
EGX64_RS00090	COG1132	(ABC) transporter
EGX64_RS00205	COG0154	amidase activity
EGX64_RS00210	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGX64_RS00215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX64_RS00220	COG4851	CamS sex pheromone cAM373 precursor
EGX64_RS00225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGX64_RS00230	COG0210	DNA helicase
EGX64_RS00235	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EGX64_RS00240	COG4496	protein, YerC YecD
EGX64_RS00245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGX64_RS00255	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EGX64_RS00260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGX64_RS00265	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EGX64_RS00275	COG0077	Prephenate dehydratase
EGX64_RS00285	COG1335	isochorismatase
EGX64_RS00290	COG1227	inorganic diphosphatase activity
EGX64_RS00295	COG1012	belongs to the aldehyde dehydrogenase family
EGX64_RS00300	COG2706	6-phosphogluconolactonase activity
EGX64_RS00345	COG1131	(ABC) transporter
EGX64_RS00355	COG1131	(ABC) transporter
EGX64_RS00360	COG1725	Transcriptional regulator
EGX64_RS00405	COG0582	viral genome integration into host DNA
EGX64_RS00410	COG0459	protein refolding
EGX64_RS00415	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EGX64_RS00450	COG3290	protein histidine kinase activity
EGX64_RS00455	COG3279	Response regulator of the LytR AlgR family
EGX64_RS00460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX64_RS00465	COG1621	beta-fructofuranosidase activity
EGX64_RS00475	COG1609	Transcriptional regulator
EGX64_RS00480	COG0004	ammonium transporteR
EGX64_RS00485	COG0425	Belongs to the sulfur carrier protein TusA family
EGX64_RS00490	COG2391	methyltransferase activity
EGX64_RS00500	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EGX64_RS00505	COG0488	(ABC) transporter
EGX64_RS00510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EGX64_RS00515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EGX64_RS00520	COG0456	acetyltransferase
EGX64_RS00525	COG1214	PFAM Peptidase M22, glycoprotease
EGX64_RS00530	COG0802	atpase or kinase
EGX64_RS00535	COG0129	dihydroxy-acid dehydratase activity
EGX64_RS00540	COG0028	Belongs to the TPP enzyme family
EGX64_RS00550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EGX64_RS00555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGX64_RS00560	COG0473	3-isopropylmalate dehydrogenase activity
EGX64_RS00565	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGX64_RS00570	COG0066	3-isopropylmalate dehydratase activity
EGX64_RS00575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGX64_RS00610	COG3091	SprT-like family
EGX64_RS00615	COG2183	response to ionizing radiation
EGX64_RS00620	COG1191	sigma factor activity
EGX64_RS00635	COG2208	phosphoserine phosphatase activity
EGX64_RS00640	COG2337	Toxic component of a toxin-antitoxin (TA) module
EGX64_RS00650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGX64_RS00655	COG0736	holo-[acyl-carrier-protein] synthase activity
EGX64_RS00660	COG3402	PFAM membrane-flanked domain
EGX64_RS00665	COG3428	Bacterial PH domain
EGX64_RS00675	COG0513	Belongs to the DEAD box helicase family
EGX64_RS00680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGX64_RS00685	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGX64_RS00690	COG0772	Belongs to the SEDS family
EGX64_RS00705	COG1937	Protein conserved in bacteria
EGX64_RS00710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX64_RS00715	COG1418	mRNA catabolic process
EGX64_RS00720	COG0706	membrane insertase activity
EGX64_RS00725	COG0352	thiamine-phosphate diphosphorylase activity
EGX64_RS00730	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EGX64_RS00740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EGX64_RS00745	COG1388	LysM domain
EGX64_RS00750	COG0629	single-stranded DNA binding
EGX64_RS00760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGX64_RS00765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGX64_RS00775	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EGX64_RS00780	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EGX64_RS00785	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EGX64_RS00790	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EGX64_RS00795	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGX64_RS00800	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EGX64_RS00810	COG0356	it plays a direct role in the translocation of protons across the membrane
EGX64_RS00820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGX64_RS00825	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EGX64_RS00830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGX64_RS00835	COG4475	Protein of unknown function (DUF436)
EGX64_RS00840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX64_RS00845	COG0009	L-threonylcarbamoyladenylate synthase
EGX64_RS00855	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX64_RS00860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EGX64_RS00865	COG1435	thymidine kinase activity
EGX64_RS00875	COG0254	rRNA binding
EGX64_RS00880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGX64_RS00885	COG1012	belongs to the aldehyde dehydrogenase family
EGX64_RS00895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGX64_RS00900	COG0191	fructose-bisphosphate aldolase activity
EGX64_RS00910	COG0504	CTP synthase activity
EGX64_RS00915	COG3343	RNA polymerase activity
EGX64_RS00925	COG5146	pantothenate kinase activity
EGX64_RS00945	COG1854	S-ribosylhomocysteine lyase activity
EGX64_RS00955	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EGX64_RS00960	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EGX64_RS00965	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGX64_RS00970	COG0813	purine-nucleoside phosphorylase activity
EGX64_RS00975	COG0783	Belongs to the Dps family
EGX64_RS01000	COG1482	cell wall glycoprotein biosynthetic process
EGX64_RS01010	COG0702	epimerase
EGX64_RS01015	COG0640	Transcriptional regulator
EGX64_RS01035	COG0561	phosphatase activity
EGX64_RS01040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGX64_RS01045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGX64_RS01055	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EGX64_RS01105	COG0489	protein tyrosine kinase activity
EGX64_RS01110	COG2814	Major facilitator Superfamily
EGX64_RS01130	COG4284	Utp--glucose-1-phosphate uridylyltransferase
EGX64_RS01135	COG1988	membrane-bound metal-dependent
EGX64_RS01145	COG2329	Antibiotic biosynthesis monooxygenase
EGX64_RS01150	COG3314	Sporulation integral membrane protein YlbJ
EGX64_RS01155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX64_RS01160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX64_RS01165	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EGX64_RS01170	COG3457	Alanine racemase
EGX64_RS01175	COG4264	IucA IucC family
EGX64_RS01180	COG2814	Major facilitator Superfamily
EGX64_RS01185	COG4264	IucA IucC family
EGX64_RS01190	COG1302	Protein conserved in bacteria
EGX64_RS01205	COG0604	alcohol dehydrogenase
EGX64_RS01210	COG2130	NADP-dependent
EGX64_RS01215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX64_RS01225	COG2723	6-phospho-beta-galactosidase activity
EGX64_RS01230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX64_RS01230	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX64_RS01235	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGX64_RS01240	COG3684	Belongs to the aldolase LacD family
EGX64_RS01245	COG1105	Belongs to the carbohydrate kinase PfkB family
EGX64_RS01250	COG0698	ribose 5-phosphate isomerase
EGX64_RS01255	COG0698	ribose 5-phosphate isomerase
EGX64_RS01260	COG1349	DNA-binding transcription factor activity
EGX64_RS01265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EGX64_RS01270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGX64_RS01275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EGX64_RS01280	COG0101	tRNA pseudouridine synthase activity
EGX64_RS01290	COG1122	ATPase activity
EGX64_RS01295	COG1122	ATPase activity
EGX64_RS01300	COG0203	ribosomal protein L17
EGX64_RS01305	COG0202	RNA polymerase activity
EGX64_RS01310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EGX64_RS01315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EGX64_RS01320	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX64_RS01325	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGX64_RS01330	COG0563	adenylate kinase activity
EGX64_RS01335	COG0201	protein transport
EGX64_RS01340	COG0200	Binds to the 23S rRNA
EGX64_RS01345	COG1841	ribosomal large subunit assembly
EGX64_RS01350	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EGX64_RS01355	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EGX64_RS01360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EGX64_RS01365	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EGX64_RS01370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGX64_RS01375	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EGX64_RS01380	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EGX64_RS01385	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGX64_RS01390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGX64_RS01400	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGX64_RS01405	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EGX64_RS01410	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EGX64_RS01415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGX64_RS01420	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EGX64_RS01425	COG0089	rRNA binding
EGX64_RS01430	COG0088	Forms part of the polypeptide exit tunnel
EGX64_RS01435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EGX64_RS01450	COG2252	PERMEase
EGX64_RS01455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX64_RS01455	COG0551	DNA topoisomerase type I activity
EGX64_RS01460	COG4975	Glucose uptake
EGX64_RS01465	COG1028	Short-chain dehydrogenase reductase Sdr
EGX64_RS01485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX64_RS01490	COG2348	transferase activity, transferring amino-acyl groups
EGX64_RS01505	COG2814	Major facilitator Superfamily
EGX64_RS01515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGX64_RS01520	COG0746	molybdenum cofactor guanylyltransferase activity
EGX64_RS01530	COG0314	molybdopterin synthase activity
EGX64_RS01540	COG0303	'Molybdopterin
EGX64_RS01545	COG0315	cyclic pyranopterin monophosphate synthase activity
EGX64_RS01550	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGX64_RS01555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGX64_RS01560	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EGX64_RS01565	COG4149	molybdate abc transporter
EGX64_RS01570	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGX64_RS01575	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EGX64_RS01585	COG1268	BioY protein
EGX64_RS01595	COG1960	acyl-CoA dehydrogenase activity
EGX64_RS01610	COG0831	urea catabolic process
EGX64_RS01615	COG0832	Belongs to the urease beta subunit family
EGX64_RS01620	COG0804	urea catabolic process
EGX64_RS01625	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EGX64_RS01630	COG0830	nickel cation binding
EGX64_RS01635	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EGX64_RS01640	COG0829	nickel cation binding
EGX64_RS01670	COG3942	CHAP domain
EGX64_RS01675	COG1757	Na H antiporter
EGX64_RS01690	COG3942	CHAP domain
EGX64_RS01695	COG2076	Multidrug Resistance protein
EGX64_RS01700	COG2076	Multidrug Resistance protein
EGX64_RS01705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX64_RS01740	COG1316	TRANSCRIPTIONal
EGX64_RS01745	COG0483	inositol monophosphate 1-phosphatase activity
EGX64_RS01755	COG1266	CAAX protease self-immunity
EGX64_RS01770	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EGX64_RS01775	COG1263	PTS System
EGX64_RS01775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX64_RS01785	COG1113	amino acid transport
EGX64_RS01805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX64_RS01815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX64_RS01815	COG1263	PTS System
EGX64_RS01820	COG1737	Transcriptional regulator
EGX64_RS01840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGX64_RS01845	COG1028	Short-chain dehydrogenase reductase Sdr
EGX64_RS01850	COG1473	amidohydrolase
EGX64_RS01855	COG0010	Belongs to the arginase family
EGX64_RS01860	COG1266	CAAX protease self-immunity
EGX64_RS01875	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGX64_RS01880	COG2258	MOSC domain
EGX64_RS01885	COG2017	converts alpha-aldose to the beta-anomer
EGX64_RS01890	COG1069	ribulokinase activity
EGX64_RS01905	COG2094	Belongs to the DNA glycosylase MPG family
EGX64_RS01925	COG0786	glutamate:sodium symporter activity
EGX64_RS01930	COG1304	FMN binding
EGX64_RS01935	COG0598	Magnesium transport protein CorA
EGX64_RS01950	COG0657	acetylesterase activity
EGX64_RS01965	COG2814	Major facilitator Superfamily
EGX64_RS01970	COG1566	PFAM secretion protein HlyD family protein
EGX64_RS01980	COG2814	Major facilitator Superfamily
EGX64_RS01985	COG4640	response to antibiotic
EGX64_RS02000	COG1136	(ABC) transporter
EGX64_RS02005	COG0577	efflux transmembrane transporter activity
EGX64_RS02010	COG0745	RESPONSE REGULATOR receiver
EGX64_RS02015	COG3850	Histidine kinase
EGX64_RS02015	COG5002	protein histidine kinase activity
EGX64_RS02020	COG0579	oxidoreductase
EGX64_RS02030	COG1620	l-lactate permease
EGX64_RS02035	COG0463	Glycosyl transferase, family 2
EGX64_RS02035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX64_RS02045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX64_RS02045	COG0463	Glycosyl transferase, family 2
EGX64_RS02050	COG0456	acetyltransferase
EGX64_RS02055	COG0604	alcohol dehydrogenase
EGX64_RS02085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX64_RS02085	COG1263	PTS System
EGX64_RS02100	COG3871	stress protein (general stress protein 26)
EGX64_RS02120	COG0778	Nitroreductase
EGX64_RS02125	COG1846	Transcriptional regulator
EGX64_RS02130	COG2223	nitrite transmembrane transporter activity
EGX64_RS02135	COG2197	response regulator
EGX64_RS02140	COG4585	Histidine kinase
EGX64_RS02150	COG2181	nitrate reductase activity
EGX64_RS02160	COG1140	nitrate reductase beta subunit
EGX64_RS02165	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EGX64_RS02175	COG2146	nitrite reductase [NAD(P)H] activity
EGX64_RS02180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX64_RS02200	COG0747	negative chemotaxis
EGX64_RS02210	COG0454	-acetyltransferase
EGX64_RS02215	COG2116	formate transmembrane transporter activity
EGX64_RS02235	COG2348	transferase activity, transferring amino-acyl groups
EGX64_RS02240	COG1126	abc transporter atp-binding protein
EGX64_RS02245	COG0765	amino acid transport
EGX64_RS02250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX64_RS02260	COG0588	phosphoglycerate mutase activity
EGX64_RS02265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EGX64_RS02280	COG1929	Belongs to the glycerate kinase type-1 family
EGX64_RS02305	COG1113	amino acid transport
EGX64_RS02310	COG0531	amino acid
EGX64_RS02320	COG0706	membrane insertase activity
EGX64_RS02325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGX64_RS02335	COG3275	phosphorelay sensor kinase activity
EGX64_RS02340	COG3279	Response regulator of the LytR AlgR family
EGX64_RS02345	COG1380	Effector of murein hydrolase LrgA
EGX64_RS02350	COG1346	cytolysis
EGX64_RS02355	COG1174	glycine betaine transport
EGX64_RS02375	COG1063	alcohol dehydrogenase
EGX64_RS02380	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EGX64_RS02385	COG0531	amino acid
EGX64_RS02390	COG2272	Belongs to the type-B carboxylesterase lipase family
EGX64_RS02395	COG2814	Major facilitator Superfamily
EGX64_RS02400	COG0390	transport system, permease component
EGX64_RS02405	COG4619	ABC transporter
EGX64_RS02425	COG0069	glutamate synthase activity
EGX64_RS02435	COG1363	Peptidase, m42
EGX64_RS02445	COG1028	Short-chain dehydrogenase reductase Sdr
EGX64_RS02455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGX64_RS02460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGX64_RS02465	COG4221	oxidoreductase activity
EGX64_RS02480	COG0556	nucleotide-excision repair
EGX64_RS02485	COG0494	nUDIX hydrolase
EGX64_RS02490	COG0438	transferase activity, transferring glycosyl groups
EGX64_RS02495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGX64_RS02500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX64_RS02505	COG2610	gluconate transmembrane transporter activity
EGX64_RS02515	COG1802	Transcriptional regulator
EGX64_RS02520	COG2271	Major facilitator Superfamily
EGX64_RS02525	COG0789	Transcriptional regulator
EGX64_RS02545	COG2357	RelA SpoT domain protein
EGX64_RS02550	COG4876	unkown
EGX64_RS02565	COG2271	Major facilitator Superfamily
EGX64_RS02575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGX64_RS02585	COG2022	thiamine diphosphate biosynthetic process
EGX64_RS02590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGX64_RS02595	COG0586	Pfam SNARE associated Golgi protein
EGX64_RS02600	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EGX64_RS02615	COG3949	Membrane
EGX64_RS02620	COG1012	belongs to the aldehyde dehydrogenase family
EGX64_RS02635	COG2514	catechol 2,3-dioxygenase activity
EGX64_RS02645	COG1012	belongs to the aldehyde dehydrogenase family
EGX64_RS02655	COG0778	Nitroreductase
EGX64_RS02660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX64_RS02670	COG3764	Sortase (surface protein transpeptidase)
EGX64_RS02685	COG1760	l-serine dehydratase
EGX64_RS02690	COG1760	l-serine dehydratase
EGX64_RS02710	COG1070	Carbohydrate kinase
EGX64_RS02720	COG1869	D-ribose catabolic process
EGX64_RS02725	COG4975	Glucose uptake
EGX64_RS02740	COG2843	Capsule synthesis protein
EGX64_RS02750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGX64_RS02765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGX64_RS02770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX64_RS02775	COG1063	alcohol dehydrogenase
EGX64_RS02780	COG1266	CAAX protease self-immunity
EGX64_RS02790	COG1263	PTS System
EGX64_RS02790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX64_RS02790	COG2190	(PTS) system
EGX64_RS02795	COG0028	Belongs to the TPP enzyme family
EGX64_RS02800	COG1346	cytolysis
EGX64_RS02805	COG1380	Effector of murein hydrolase LrgA
EGX64_RS02810	COG0583	DNA-binding transcription factor activity
EGX64_RS02830	COG3425	synthase
EGX64_RS02835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX64_RS02860	COG1012	belongs to the aldehyde dehydrogenase family
EGX64_RS02865	COG1028	Short-chain dehydrogenase reductase Sdr
EGX64_RS02875	COG2217	Heavy metal translocating P-type atpase
EGX64_RS02880	COG2608	mercury ion transmembrane transporter activity
EGX64_RS02895	COG0436	Aminotransferase
EGX64_RS02905	COG3942	CHAP domain
EGX64_RS02915	COG0741	lytic transglycosylase activity
EGX64_RS02935	COG1113	amino acid transport
EGX64_RS02940	COG3001	Fructosamine kinase
EGX64_RS02945	COG0167	dihydroorotate dehydrogenase activity
EGX64_RS02955	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGX64_RS02970	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EGX64_RS02975	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EGX64_RS02980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EGX64_RS02990	COG3527	Alpha-acetolactate decarboxylase
EGX64_RS02995	COG0028	Belongs to the TPP enzyme family
EGX64_RS03000	COG0039	L-malate dehydrogenase activity
EGX64_RS03005	COG0583	DNA-binding transcription factor activity
EGX64_RS03010	COG0531	amino acid
EGX64_RS03045	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX64_RS03055	COG3588	fructose-bisphosphate aldolase
EGX64_RS03065	COG0579	oxidoreductase
EGX64_RS03070	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EGX64_RS03075	COG0574	Belongs to the PEP-utilizing enzyme family
EGX64_RS03075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX64_RS03080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGX64_RS03095	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EGX64_RS03100	COG1012	belongs to the aldehyde dehydrogenase family
EGX64_RS03105	COG1510	regulation of RNA biosynthetic process
EGX64_RS03120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EGX64_RS03125	COG0602	queuosine metabolic process
EGX64_RS03130	COG1328	CTP reductase activity
EGX64_RS03140	COG0529	Catalyzes the synthesis of activated sulfate
EGX64_RS03145	COG2046	Belongs to the sulfate adenylyltransferase family
EGX64_RS03150	COG0730	response to heat
EGX64_RS03165	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX64_RS03170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGX64_RS03175	COG0175	sulfate reduction
EGX64_RS03185	COG0386	Belongs to the glutathione peroxidase family
EGX64_RS03190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX64_RS03195	COG1846	Transcriptional regulator
EGX64_RS03235	COG1136	(ABC) transporter
EGX64_RS03240	COG2205	protein histidine kinase activity
EGX64_RS03255	COG1785	Belongs to the alkaline phosphatase family
EGX64_RS03260	COG0702	epimerase
EGX64_RS03265	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX64_RS03275	COG4195	phage-related replication protein
EGX64_RS03400	COG1388	LysM domain
EGX64_RS03400	COG3942	CHAP domain
EGX64_RS03415	COG3961	Belongs to the TPP enzyme family
EGX64_RS03425	COG2843	Capsule synthesis protein
EGX64_RS03435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGX64_RS03445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EGX64_RS03450	COG2235	arginine
EGX64_RS03455	COG1438	arginine binding
EGX64_RS03460	COG3227	Zinc metalloprotease (Elastase)
EGX64_RS03495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX64_RS03495	COG3711	transcriptional antiterminator
EGX64_RS03500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX64_RS03500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX64_RS03500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX64_RS03505	COG1482	cell wall glycoprotein biosynthetic process
EGX64_RS03515	COG1705	Flagellar rod assembly protein muramidase FlgJ
EGX64_RS03515	COG3942	CHAP domain
EGX64_RS03525	COG1764	response to oxidative stress
EGX64_RS03540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGX64_RS03545	COG2814	Major facilitator Superfamily
EGX64_RS03575	COG0653	protein targeting
EGX64_RS03600	COG3639	organic phosphonate transmembrane transporter activity
EGX64_RS03605	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EGX64_RS03620	COG0737	Belongs to the 5'-nucleotidase family
EGX64_RS03625	COG2814	Major facilitator Superfamily
EGX64_RS03650	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EGX64_RS03660	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EGX64_RS03665	COG0140	phosphoribosyl-ATP diphosphatase activity
EGX64_RS03665	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGX64_RS03670	COG0107	imidazoleglycerol-phosphate synthase activity
EGX64_RS03675	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EGX64_RS03680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGX64_RS03685	COG0131	Imidazoleglycerol-phosphate dehydratase
EGX64_RS03690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGX64_RS03695	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EGX64_RS03700	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EGX64_RS03725	COG0579	oxidoreductase
EGX64_RS03735	COG2353	YceI-like domain
EGX64_RS03740	COG3386	PFAM SMP-30 Gluconolaconase
EGX64_RS03745	COG1054	Belongs to the UPF0176 family
EGX64_RS03750	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EGX64_RS03770	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX64_RS03775	COG0022	dehydrogenase e1 component
EGX64_RS03780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGX64_RS03785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX64_RS03790	COG0471	metal ion transport
EGX64_RS03795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGX64_RS03800	COG2962	Rard protein
EGX64_RS03815	COG2814	Major facilitator Superfamily
EGX64_RS03850	COG2814	Major facilitator Superfamily
EGX64_RS03870	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EGX64_RS03875	COG1461	Dihydroxyacetone kinase
EGX64_RS03880	COG2376	Dihydroxyacetone kinase
EGX64_RS03890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EGX64_RS03895	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EGX64_RS03910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EGX64_RS03915	COG0549	Belongs to the carbamate kinase family
EGX64_RS03920	COG1288	antiporter activity
EGX64_RS03955	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGX64_RS03960	COG3246	L-lysine catabolic process to acetate
EGX64_RS03965	COG1309	transcriptional regulator
EGX64_RS03970	COG1114	Component of the transport system for branched-chain amino acids
EGX64_RS03975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGX64_RS03980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGX64_RS03985	COG1882	Formate acetyltransferase
EGX64_RS03995	COG1124	(ABC) transporter
EGX64_RS04000	COG0444	Belongs to the ABC transporter superfamily
EGX64_RS04010	COG0601	transmembrane transport
EGX64_RS04065	COG1028	Short-chain dehydrogenase reductase Sdr
EGX64_RS04075	COG3976	FMN-binding domain protein
EGX64_RS04075	COG1053	succinate dehydrogenase
EGX64_RS04075	COG0431	NADPH-dependent FMN reductase
EGX64_RS04085	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX64_RS04100	COG0523	cobalamin synthesis protein
EGX64_RS04125	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EGX64_RS04130	COG0156	8-amino-7-oxononanoate synthase activity
EGX64_RS04135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EGX64_RS04140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGX64_RS04155	COG1131	(ABC) transporter
EGX64_RS04170	COG0438	transferase activity, transferring glycosyl groups
EGX64_RS04175	COG0653	protein targeting
EGX64_RS04185	COG1073	alpha beta
EGX64_RS04195	COG0201	protein transport
EGX64_RS04200	COG3391	amine dehydrogenase activity
EGX64_RS04240	COG1755	Isoprenylcysteine carboxyl methyltransferase
EGX64_RS04245	COG0579	oxidoreductase
EGX64_RS04250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX64_RS04290	COG0668	transmembrane transport
EGX64_RS04320	COG0640	Transcriptional regulator
EGX64_RS04340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX64_RS04345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX64_RS04350	COG0730	response to heat
EGX64_RS04355	COG1937	Protein conserved in bacteria
EGX64_RS04360	COG2210	Belongs to the sulfur carrier protein TusA family
EGX64_RS04365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX64_RS04370	COG1388	LysM domain
EGX64_RS04375	COG2132	Multicopper oxidase
EGX64_RS04380	COG2217	Heavy metal translocating P-type atpase
EGX64_RS04395	COG0076	glutamate decarboxylase activity
EGX64_RS04405	COG0210	DNA helicase
EGX64_RS04410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGX64_RS04415	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EGX64_RS04425	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EGX64_RS04455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EGX64_RS04515	COG2030	dehydratase
EGX64_RS04520	COG0584	glycerophosphoryl diester phosphodiesterase
EGX64_RS04530	COG3425	synthase
EGX64_RS04570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX64_RS04570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX64_RS04590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EGX64_RS04595	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGX64_RS04605	COG4863	YycH protein
EGX64_RS04610	COG5002	protein histidine kinase activity
EGX64_RS04615	COG0745	RESPONSE REGULATOR receiver
EGX64_RS04635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGX64_RS04640	COG0305	Participates in initiation and elongation during chromosome replication
EGX64_RS04645	COG0359	binds to the 23S rRNA
EGX64_RS04650	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EGX64_RS04660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGX64_RS04680	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EGX64_RS04685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGX64_RS04690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX64_RS04695	COG0187	DNA topoisomerase II activity
EGX64_RS04700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGX64_RS04705	COG2501	S4 domain
EGX64_RS04710	COG0592	DNA-directed DNA polymerase activity
EGX64_RS04715	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGX64_RS04725	COG0594	ribonuclease P activity
EGX64_RS04730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EGX64_RS04735	COG0445	tRNA wobble uridine modification
EGX64_RS04740	COG0357	Ribosomal RNA small subunit methyltransferase G
EGX64_RS04745	COG1475	DNA binding
EGX64_RS04785	COG1136	(ABC) transporter
EGX64_RS04790	COG0577	efflux transmembrane transporter activity
EGX64_RS04805	COG0577	efflux transmembrane transporter activity
EGX64_RS04810	COG1136	(ABC) transporter
EGX64_RS04835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX64_RS04855	COG4555	ABC transporter
EGX64_RS04865	COG1476	TRANSCRIPTIONal
EGX64_RS04880	COG0183	Belongs to the thiolase family
EGX64_RS04890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EGX64_RS04895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EGX64_RS04895	COG0646	methionine synthase
EGX64_RS04900	COG0626	cystathionine gamma-synthase activity
EGX64_RS04905	COG0626	cystathionine gamma-synthase activity
EGX64_RS04915	COG1475	DNA binding
EGX64_RS04920	COG0668	transmembrane transport
EGX64_RS04925	COG4481	Protein conserved in bacteria
EGX64_RS04930	COG0012	GTP binding
EGX64_RS04945	COG0360	Binds together with S18 to 16S ribosomal RNA
EGX64_RS04955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGX64_RS04975	COG0693	protein deglycase activity
EGX64_RS04985	COG1846	Transcriptional regulator
EGX64_RS05025	COG1280	lysine exporter protein (LysE YggA)
EGX64_RS05055	COG3634	alkyl hydroperoxide reductase activity
EGX64_RS05060	COG0450	alkyl hydroperoxide reductase
EGX64_RS05070	COG0778	Nitroreductase
EGX64_RS05075	COG1823	symporter activity
EGX64_RS05080	COG5183	chlorophyll binding
EGX64_RS05095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX64_RS05100	COG2233	PERMEase
EGX64_RS05105	COG0516	GMP reductase activity
EGX64_RS05105	COG0517	IMP dehydrogenase activity
EGX64_RS05110	COG0519	Catalyzes the synthesis of GMP from XMP
EGX64_RS05110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGX64_RS05155	COG0523	cobalamin synthesis protein
EGX64_RS05175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX64_RS05180	COG3002	Belongs to the UPF0753 family
EGX64_RS05190	COG5609	conserved protein (DUF2294)
EGX64_RS05205	COG1647	Serine aminopeptidase, S33
EGX64_RS05215	COG0733	neurotransmitter:sodium symporter activity
EGX64_RS05225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGX64_RS05230	COG0626	cystathionine gamma-synthase activity
EGX64_RS05235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGX64_RS05240	COG2011	ABC-type metal ion transport system permease component
EGX64_RS05250	COG3942	CHAP domain
EGX64_RS05250	COG1388	LysM domain
EGX64_RS05255	COG0438	transferase activity, transferring glycosyl groups
EGX64_RS05280	COG0583	DNA-binding transcription factor activity
EGX64_RS05285	COG0070	glutamate synthase
EGX64_RS05285	COG0069	glutamate synthase activity
EGX64_RS05285	COG0067	glutamate synthase
EGX64_RS05290	COG0493	'glutamate synthase
EGX64_RS05315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGX64_RS05320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EGX64_RS05325	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EGX64_RS05350	COG1982	Orn Lys Arg decarboxylase major
EGX64_RS05355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EGX64_RS05360	COG3870	Protein conserved in bacteria
EGX64_RS05365	COG0470	DNA polymerase III
EGX64_RS05370	COG1774	PSP1 C-terminal conserved region
EGX64_RS05375	COG4467	Involved in initiation control of chromosome replication
EGX64_RS05380	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EGX64_RS05385	COG2827	Endonuclease containing a URI domain
EGX64_RS05390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGX64_RS05395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX64_RS05395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX64_RS05400	COG0084	hydrolase, TatD family'
EGX64_RS05405	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EGX64_RS05410	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGX64_RS05415	COG4466	Protein conserved in bacteria
EGX64_RS05420	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EGX64_RS05425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX64_RS05430	COG0251	oxidation-reduction process
EGX64_RS05435	COG2088	sporulation resulting in formation of a cellular spore
EGX64_RS05440	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGX64_RS05445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGX64_RS05450	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EGX64_RS05455	COG0193	aminoacyl-tRNA hydrolase activity
EGX64_RS05460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGX64_RS05465	COG2244	polysaccharide biosynthetic process
EGX64_RS05470	COG3956	TIGRFAM MazG family protein
EGX64_RS05475	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGX64_RS05485	COG1098	S1 RNA binding domain
EGX64_RS05490	COG0037	tRNA processing
EGX64_RS05495	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EGX64_RS05500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGX64_RS05505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EGX64_RS05510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGX64_RS05515	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGX64_RS05520	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGX64_RS05525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGX64_RS05530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGX64_RS05615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX64_RS05620	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EGX64_RS05625	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EGX64_RS05630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX64_RS05635	COG4463	regulation of RNA biosynthetic process
EGX64_RS05640	COG3880	PFAM UvrB UvrC protein
EGX64_RS05645	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EGX64_RS05650	COG0542	response to heat
EGX64_RS05655	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EGX64_RS05660	COG4956	integral membrane protein (PIN domain superfamily)
EGX64_RS05665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGX64_RS05670	COG1045	serine acetyltransferase
EGX64_RS05675	COG0215	cysteine-tRNA ligase activity
EGX64_RS05680	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EGX64_RS05685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX64_RS05690	COG3688	RNA-binding protein containing a PIN domain
EGX64_RS05700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGX64_RS05705	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX64_RS05710	COG0250	Participates in transcription elongation, termination and antitermination
EGX64_RS05715	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EGX64_RS05720	COG0081	regulation of translation
EGX64_RS05730	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EGX64_RS05735	COG0222	ribosome binding
EGX64_RS05740	COG2813	Specifically methylates the guanine in position
EGX64_RS05745	COG0085	RNA polymerase activity
EGX64_RS05750	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EGX64_RS05760	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGX64_RS05770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EGX64_RS05775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EGX64_RS05780	COG1473	amidohydrolase
EGX64_RS05800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX64_RS05805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX64_RS05810	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EGX64_RS05815	COG1063	alcohol dehydrogenase
EGX64_RS05820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX64_RS05830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX64_RS05840	COG1428	Deoxynucleoside kinase
EGX64_RS05845	COG1428	Deoxynucleoside kinase
EGX64_RS05860	COG0561	phosphatase activity
EGX64_RS05865	COG0431	NADPH-dependent FMN reductase
EGX64_RS05880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX64_RS05885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX64_RS05895	COG1469	GTP cyclohydrolase I activity
EGX64_RS05900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGX64_RS05910	COG0363	glucosamine-6-phosphate deaminase activity
EGX64_RS05915	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EGX64_RS05930	COG0318	PFAM AMP-dependent synthetase and ligase
EGX64_RS05935	COG0183	Belongs to the thiolase family
EGX64_RS05950	COG0477	Major facilitator Superfamily
EGX64_RS05960	COG0351	phosphomethylpyrimidine kinase
EGX64_RS05970	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EGX64_RS05980	COG2363	Small membrane protein
EGX64_RS05985	COG0531	amino acid
EGX64_RS06000	COG3253	May function as heme-dependent peroxidase
EGX64_RS06005	COG0280	phosphate acetyltransferase
EGX64_RS06010	COG0095	Lipoate-protein ligase
EGX64_RS06030	COG4844	belongs to the
EGX64_RS06035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX64_RS06055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGX64_RS06080	COG3646	Phage regulatory protein
EGX64_RS06080	COG3645	SOS response
EGX64_RS06125	COG1484	DNA-dependent DNA replication
EGX64_RS06190	COG0756	dUTP diphosphatase activity
EGX64_RS06220	COG1783	phage Terminase large subunit
EGX64_RS06355	COG1388	LysM domain
EGX64_RS06355	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX64_RS06360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX64_RS06370	COG0667	Aldo Keto reductase
EGX64_RS06375	COG2409	Drug exporters of the RND superfamily
EGX64_RS06380	COG2113	Glycine betaine
EGX64_RS06405	COG1078	dGTPase activity
EGX64_RS06415	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EGX64_RS06420	COG1691	(AIR) carboxylase
EGX64_RS06425	COG1606	tRNA processing
EGX64_RS06430	COG3875	lactate racemase activity
EGX64_RS06435	COG1064	alcohol dehydrogenase
EGX64_RS06455	COG0018	arginyl-trna synthetase
EGX64_RS06460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX64_RS06475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX64_RS06480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX64_RS06485	COG0546	phosphoglycolate phosphatase activity
EGX64_RS06505	COG0596	Alpha beta hydrolase
EGX64_RS06545	COG2111	Na H antiporter
EGX64_RS06545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX64_RS06550	COG2111	Na H antiporter
EGX64_RS06555	COG1006	Multisubunit Na H antiporter MnhC subunit
EGX64_RS06560	COG0651	ATP synthesis coupled electron transport
EGX64_RS06565	COG1863	multisubunit Na H antiporter MnhE subunit
EGX64_RS06570	COG2212	antiporter activity
EGX64_RS06575	COG1320	monovalent cation:proton antiporter activity
EGX64_RS06585	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX64_RS06590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX64_RS06595	COG1121	(ABC) transporter
EGX64_RS06600	COG1321	iron dependent repressor
EGX64_RS06610	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EGX64_RS06615	COG1134	teichoic acid transport
EGX64_RS06620	COG1682	transport, permease protein
EGX64_RS06625	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX64_RS06635	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EGX64_RS06645	COG1132	(ABC) transporter
EGX64_RS06650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX64_RS06660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGX64_RS06665	COG1120	ATPase activity
EGX64_RS06675	COG3949	Membrane
EGX64_RS06690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX64_RS06695	COG0745	RESPONSE REGULATOR receiver
EGX64_RS06700	COG2205	protein histidine kinase activity
EGX64_RS06705	COG1136	(ABC) transporter
EGX64_RS06710	COG0577	efflux transmembrane transporter activity
EGX64_RS06715	COG1392	Phosphate transport regulator
EGX64_RS06720	COG0306	phosphate transporter
EGX64_RS06725	COG1388	LysM domain
EGX64_RS06725	COG3942	CHAP domain
EGX64_RS06745	COG0217	transcriptional regulatory protein
EGX64_RS06755	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EGX64_RS06775	COG0583	DNA-binding transcription factor activity
EGX64_RS06780	COG2814	Major facilitator Superfamily
EGX64_RS06785	COG2839	Protein conserved in bacteria
EGX64_RS06810	COG1611	Belongs to the LOG family
EGX64_RS06815	COG1671	Belongs to the UPF0178 family
EGX64_RS06830	COG1968	undecaprenyl-diphosphatase activity
EGX64_RS06835	COG4988	ABC transporter
EGX64_RS06840	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGX64_RS06865	COG0039	L-malate dehydrogenase activity
EGX64_RS06870	COG0471	metal ion transport
EGX64_RS06875	COG0415	Belongs to the DNA photolyase family
EGX64_RS06900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGX64_RS06910	COG1349	DNA-binding transcription factor activity
EGX64_RS06915	COG1105	Belongs to the carbohydrate kinase PfkB family
EGX64_RS06920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX64_RS06920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX64_RS06920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX64_RS06950	COG1733	regulation of RNA biosynthetic process
EGX64_RS06970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGX64_RS06975	COG1253	flavin adenine dinucleotide binding
EGX64_RS06980	COG0656	L-ascorbic acid biosynthetic process
EGX64_RS06990	COG0463	Glycosyl transferase, family 2
EGX64_RS06995	COG5002	protein histidine kinase activity
EGX64_RS07000	COG0745	RESPONSE REGULATOR receiver
EGX64_RS07025	COG0602	queuosine metabolic process
EGX64_RS07030	COG0720	synthase
EGX64_RS07035	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EGX64_RS07045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGX64_RS07060	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGX64_RS07070	COG1368	sulfuric ester hydrolase activity
EGX64_RS07085	COG0488	(ABC) transporter
EGX64_RS07090	COG0514	ATP-dependent DNA helicase (RecQ)
EGX64_RS07095	COG0517	IMP dehydrogenase activity
EGX64_RS07095	COG1125	glycine betaine transport
EGX64_RS07100	COG1174	glycine betaine transport
EGX64_RS07105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGX64_RS07110	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EGX64_RS07120	COG1012	belongs to the aldehyde dehydrogenase family
EGX64_RS07120	COG1454	alcohol dehydrogenase
EGX64_RS07125	COG1597	lipid kinase activity
EGX64_RS07130	COG3104	oligopeptide transport
EGX64_RS07135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EGX64_RS07145	COG1780	Probably involved in ribonucleotide reductase function
EGX64_RS07150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX64_RS07155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX64_RS07165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX64_RS07170	COG4605	iron ion homeostasis
EGX64_RS07175	COG4604	ABC transporter, ATP-binding protein
EGX64_RS07190	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGX64_RS07210	COG1929	Belongs to the glycerate kinase type-1 family
EGX64_RS07215	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX64_RS07230	COG2199	diguanylate cyclase activity
EGX64_RS07235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGX64_RS07240	COG1739	Uncharacterized protein family UPF0029
EGX64_RS07250	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EGX64_RS07255	COG1040	competence protein
EGX64_RS07260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGX64_RS07265	COG0653	protein targeting
EGX64_RS07275	COG1388	LysM domain
EGX64_RS07275	COG3942	CHAP domain
EGX64_RS07305	COG0556	nucleotide-excision repair
EGX64_RS07310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX64_RS07315	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EGX64_RS07320	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EGX64_RS07335	COG0492	ferredoxin-NADP+ reductase activity
EGX64_RS07340	COG1660	Displays ATPase and GTPase activities
EGX64_RS07345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EGX64_RS07350	COG1481	regulation of sporulation
EGX64_RS07360	COG0740	serine-type endopeptidase activity
EGX64_RS07370	COG1090	epimerase
EGX64_RS07390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGX64_RS07395	COG0126	phosphoglycerate kinase activity
EGX64_RS07400	COG0149	triose-phosphate isomerase activity
EGX64_RS07405	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EGX64_RS07410	COG0148	phosphopyruvate hydratase activity
EGX64_RS07420	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX64_RS07425	COG1647	Serine aminopeptidase, S33
EGX64_RS07430	COG0557	exoribonuclease II activity
EGX64_RS07435	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EGX64_RS07445	COG0582	viral genome integration into host DNA
EGX64_RS07510	COG3728	DNA packaging
EGX64_RS07510	COG5484	DNA packaging
EGX64_RS07585	COG0110	maltose O-acetyltransferase activity
EGX64_RS07620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGX64_RS07660	COG1278	Cold shock
EGX64_RS07675	COG4195	phage-related replication protein
EGX64_RS07725	COG1764	response to oxidative stress
EGX64_RS07730	COG0710	3-dehydroquinate dehydratase activity
EGX64_RS07740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX64_RS07745	COG1393	Belongs to the ArsC family
EGX64_RS07750	COG0509	glycine decarboxylation via glycine cleavage system
EGX64_RS07760	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EGX64_RS07770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGX64_RS07775	COG2011	ABC-type metal ion transport system permease component
EGX64_RS07780	COG1464	Belongs to the NlpA lipoprotein family
EGX64_RS07790	COG3237	CsbD-like
EGX64_RS07800	COG0396	ATPase activity
EGX64_RS07805	COG0719	Fe-S assembly protein
EGX64_RS07810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGX64_RS07815	COG0822	iron-sulfur transferase activity
EGX64_RS07820	COG0719	Fe-S assembly protein
EGX64_RS07835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGX64_RS07850	COG3682	Transcriptional regulator
EGX64_RS07880	COG1253	flavin adenine dinucleotide binding
EGX64_RS07885	COG1801	Protein of unknown function DUF72
EGX64_RS07890	COG0730	response to heat
EGX64_RS07895	COG0737	Belongs to the 5'-nucleotidase family
EGX64_RS07900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGX64_RS07905	COG4470	Protein conserved in bacteria
EGX64_RS07915	COG2445	Protein of unknown function DUF86
EGX64_RS07920	COG0647	UMP catabolic process
EGX64_RS07935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX64_RS07940	COG1696	Membrane protein involved in D-alanine export
EGX64_RS07945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX64_RS07950	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EGX64_RS07955	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EGX64_RS07960	COG4837	Protein of unknown function (DUF1462)
EGX64_RS07965	COG1252	NADH dehydrogenase
EGX64_RS07970	COG4844	belongs to the
EGX64_RS07975	COG0316	Belongs to the HesB IscA family
EGX64_RS07980	COG1252	NADH dehydrogenase
EGX64_RS07985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGX64_RS07990	COG2056	Na+-H+ antiporter family
EGX64_RS07995	COG2050	protein possibly involved in aromatic compounds catabolism
EGX64_RS08005	COG1320	monovalent cation:proton antiporter activity
EGX64_RS08010	COG2212	antiporter activity
EGX64_RS08015	COG1863	multisubunit Na H antiporter MnhE subunit
EGX64_RS08020	COG0651	ATP synthesis coupled electron transport
EGX64_RS08025	COG1006	Multisubunit Na H antiporter MnhC subunit
EGX64_RS08030	COG2111	Na H antiporter
EGX64_RS08035	COG2111	Na H antiporter
EGX64_RS08035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX64_RS08045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX64_RS08050	COG1098	S1 RNA binding domain
EGX64_RS08055	COG1902	pentaerythritol trinitrate reductase activity
EGX64_RS08060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGX64_RS08070	COG0584	glycerophosphoryl diester phosphodiesterase
EGX64_RS08075	COG0165	Argininosuccinate lyase
EGX64_RS08080	COG0137	argininosuccinate synthase activity
EGX64_RS08085	COG0166	Belongs to the GPI family
EGX64_RS08095	COG0398	Pfam SNARE associated Golgi protein
EGX64_RS08110	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EGX64_RS08115	COG1074	ATP-dependent DNA helicase activity
EGX64_RS08120	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGX64_RS08130	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX64_RS08135	COG0561	phosphatase activity
EGX64_RS08150	COG0542	response to heat
EGX64_RS08175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGX64_RS08190	COG0601	transmembrane transport
EGX64_RS08195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX64_RS08200	COG0444	Belongs to the ABC transporter superfamily
EGX64_RS08205	COG4608	Belongs to the ABC transporter superfamily
EGX64_RS08210	COG4166	transmembrane transport
EGX64_RS08215	COG0180	Tryptophanyl-tRNA synthetase
EGX64_RS08220	COG1393	Belongs to the ArsC family
EGX64_RS08225	COG4862	establishment of competence for transformation
EGX64_RS08235	COG1164	Oligoendopeptidase f
EGX64_RS08240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EGX64_RS08245	COG2346	COG2346, Truncated hemoglobins
EGX64_RS08260	COG2357	RelA SpoT domain protein
EGX64_RS08265	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGX64_RS08270	COG0564	pseudouridine synthase activity
EGX64_RS08275	COG2239	Acts as a magnesium transporter
EGX64_RS08280	COG0475	glutathione-regulated potassium exporter activity
EGX64_RS08280	COG0569	domain protein
EGX64_RS08310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGX64_RS08315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGX64_RS08320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGX64_RS08405	COG0210	DNA helicase
EGX64_RS08410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGX64_RS08430	COG1002	Type II restriction enzyme, methylase subunits
EGX64_RS08440	COG0628	permease
EGX64_RS08445	COG2382	esterase
EGX64_RS08450	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EGX64_RS08455	COG2814	Major facilitator Superfamily
EGX64_RS08460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGX64_RS08465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX64_RS08475	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EGX64_RS08480	COG0861	Integral membrane protein TerC family
EGX64_RS08485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX64_RS08490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGX64_RS08495	COG0737	Belongs to the 5'-nucleotidase family
EGX64_RS08505	COG4873	Protein conserved in bacteria
EGX64_RS08570	COG1279	arginine transmembrane transporter activity
EGX64_RS08585	COG2314	TM2 domain
EGX64_RS08595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX64_RS08605	COG1575	Belongs to the MenA family. Type 1 subfamily
EGX64_RS08615	COG1169	isochorismate synthase
EGX64_RS08620	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EGX64_RS08630	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EGX64_RS08640	COG0436	Aminotransferase
EGX64_RS08645	COG3594	Acyltransferase
EGX64_RS08670	COG1316	TRANSCRIPTIONal
EGX64_RS08685	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGX64_RS08690	COG1845	cytochrome c oxidase, subunit III
EGX64_RS08695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGX64_RS08700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGX64_RS08710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EGX64_RS08715	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGX64_RS08720	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGX64_RS08725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EGX64_RS08730	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGX64_RS08735	COG0047	phosphoribosylformylglycinamidine synthase activity
EGX64_RS08740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGX64_RS08745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EGX64_RS08750	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGX64_RS08755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGX64_RS08760	COG0138	bifunctional purine biosynthesis protein purh
EGX64_RS08765	COG0151	Belongs to the GarS family
EGX64_RS08770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EGX64_RS08775	COG4172	Belongs to the ABC transporter superfamily
EGX64_RS08785	COG4716	Myosin-crossreactive antigen
EGX64_RS08800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EGX64_RS08810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX64_RS08815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX64_RS08825	COG1271	oxidase subunit
EGX64_RS08835	COG0569	domain protein
EGX64_RS08840	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EGX64_RS08845	COG5503	Protein of unknown function (DUF1447)
EGX64_RS08850	COG0242	peptide deformylase activity
EGX64_RS08860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGX64_RS08865	COG0022	dehydrogenase e1 component
EGX64_RS08870	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX64_RS08880	COG4476	Belongs to the UPF0223 family
EGX64_RS08890	COG3842	ATPase activity
EGX64_RS08895	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX64_RS08920	COG1914	H( )-stimulated, divalent metal cation uptake system
EGX64_RS08925	COG4493	Belongs to the UPF0637 family
EGX64_RS08930	COG0483	inositol monophosphate 1-phosphatase activity
EGX64_RS08940	COG1217	gtp-binding protein TYPA
EGX64_RS08945	COG4896	Protein conserved in bacteria
EGX64_RS08950	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGX64_RS08955	COG4838	Belongs to the UPF0358 family
EGX64_RS08960	COG0772	Belongs to the SEDS family
EGX64_RS08970	COG1612	heme a metabolic process
EGX64_RS08975	COG0109	protoheme IX farnesyltransferase activity
EGX64_RS08985	COG2340	Cysteine-rich secretory protein family
EGX64_RS08990	COG3679	Belongs to the UPF0342 family
EGX64_RS08995	COG0584	glycerophosphoryl diester phosphodiesterase
EGX64_RS09005	COG4471	UPF0298 protein
EGX64_RS09015	COG0742	ribosomal rna small subunit methyltransferase
EGX64_RS09020	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EGX64_RS09025	COG1323	Belongs to the UPF0348 family
EGX64_RS09040	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGX64_RS09055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX64_RS09060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EGX64_RS09065	COG0072	phenylalanine-tRNA ligase activity
EGX64_RS09065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX64_RS09070	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGX64_RS09075	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EGX64_RS09085	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EGX64_RS09085	COG1796	DNA polymerase
EGX64_RS09090	COG1193	negative regulation of DNA recombination
EGX64_RS09095	COG3118	belongs to the thioredoxin family
EGX64_RS09100	COG0322	excinuclease ABC activity
EGX64_RS09110	COG2009	succinate dehydrogenase
EGX64_RS09115	COG1053	succinate dehydrogenase
EGX64_RS09120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGX64_RS09125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGX64_RS09130	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGX64_RS09165	COG1011	Hydrolase
EGX64_RS09170	COG0454	-acetyltransferase
EGX64_RS09175	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EGX64_RS09180	COG2001	Belongs to the MraZ family
EGX64_RS09185	COG0275	rRNA processing
EGX64_RS09190	COG4839	cell division protein FtsL
EGX64_RS09195	COG0768	penicillin binding
EGX64_RS09200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGX64_RS09205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGX64_RS09210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGX64_RS09215	COG0849	cell division
EGX64_RS09220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGX64_RS09225	COG1496	oxidoreductase activity
EGX64_RS09230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGX64_RS09235	COG1799	cell septum assembly
EGX64_RS09240	COG0762	integral membrane protein
EGX64_RS09250	COG3599	regulation of cell shape
EGX64_RS09255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGX64_RS09265	COG1388	LysM domain
EGX64_RS09265	COG3942	CHAP domain
EGX64_RS09270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EGX64_RS09275	COG0564	pseudouridine synthase activity
EGX64_RS09280	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EGX64_RS09285	COG2233	PERMEase
EGX64_RS09290	COG0540	Belongs to the ATCase OTCase family
EGX64_RS09295	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EGX64_RS09300	COG0505	Belongs to the CarA family
EGX64_RS09305	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGX64_RS09310	COG0284	orotidine-5'-phosphate decarboxylase activity
EGX64_RS09315	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EGX64_RS09335	COG0194	GDP metabolic process
EGX64_RS09340	COG1758	RNA polymerase activity
EGX64_RS09345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGX64_RS09350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGX64_RS09360	COG0242	peptide deformylase activity
EGX64_RS09365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EGX64_RS09370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGX64_RS09370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGX64_RS09375	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EGX64_RS09380	COG0631	protein serine/threonine phosphatase activity
EGX64_RS09390	COG1162	GTPase activity
EGX64_RS09395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGX64_RS09405	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EGX64_RS09410	COG1302	Protein conserved in bacteria
EGX64_RS09415	COG1461	Dihydroxyacetone kinase
EGX64_RS09420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX64_RS09425	COG1349	DNA-binding transcription factor activity
EGX64_RS09430	COG0416	fatty acid biosynthetic process
EGX64_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
EGX64_RS09445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX64_RS09450	COG0571	ribonuclease III activity
EGX64_RS09455	COG1196	nuclear chromosome segregation
EGX64_RS09460	COG0552	protein localization to endoplasmic reticulum
EGX64_RS09465	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EGX64_RS09470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGX64_RS09475	COG0228	four-way junction DNA binding
EGX64_RS09480	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EGX64_RS09485	COG0336	Belongs to the RNA methyltransferase TrmD family
EGX64_RS09490	COG0335	large ribosomal subunit rRNA binding
EGX64_RS09500	COG4485	Bacterial membrane protein, YfhO
EGX64_RS09510	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGX64_RS09515	COG0045	succinate-CoA ligase (ADP-forming) activity
EGX64_RS09520	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGX64_RS09525	COG0758	DNA mediated transformation
EGX64_RS09530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX64_RS09535	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EGX64_RS09540	COG4974	Belongs to the 'phage' integrase family
EGX64_RS09545	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EGX64_RS09550	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EGX64_RS09555	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EGX64_RS09560	COG0052	Belongs to the universal ribosomal protein uS2 family
EGX64_RS09565	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EGX64_RS09570	COG0528	UMP kinase activity
EGX64_RS09575	COG0233	cytoplasmic translational termination
EGX64_RS09580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGX64_RS09585	COG4589	Belongs to the CDS family
EGX64_RS09595	COG0442	prolyl-tRNA aminoacylation
EGX64_RS09600	COG2176	DNA-directed DNA polymerase activity
EGX64_RS09605	COG0779	Required for maturation of 30S ribosomal subunits
EGX64_RS09610	COG0195	Participates in both transcription termination and antitermination
EGX64_RS09615	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EGX64_RS09620	COG1358	cellular component organization or biogenesis
EGX64_RS09625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EGX64_RS09630	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EGX64_RS09635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGX64_RS09640	COG0196	riboflavin kinase activity
EGX64_RS09645	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EGX64_RS09650	COG1185	polyribonucleotide nucleotidyltransferase activity
EGX64_RS09655	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EGX64_RS09660	COG1674	ftsk spoiiie
EGX64_RS09665	COG2188	Transcriptional regulator
EGX64_RS09670	COG0612	Peptidase, M16
EGX64_RS09675	COG0612	Peptidase, M16
EGX64_RS09680	COG0300	oxidoreductase activity
EGX64_RS09695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGX64_RS09700	COG1546	Belongs to the CinA family
EGX64_RS09700	COG1058	Belongs to the CinA family
EGX64_RS09705	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGX64_RS09710	COG1418	mRNA catabolic process
EGX64_RS09720	COG1692	metallophosphoesterase
EGX64_RS09725	COG0674	pyruvate-flavodoxin oxidoreductase activity
EGX64_RS09725	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EGX64_RS09730	COG1013	pyruvate-flavodoxin oxidoreductase activity
EGX64_RS09735	COG4195	phage-related replication protein
EGX64_RS09745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGX64_RS09750	COG4550	Control of competence regulator ComK, YlbF/YmcA
EGX64_RS09760	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EGX64_RS09765	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGX64_RS09770	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EGX64_RS09775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGX64_RS09780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX64_RS09785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX64_RS09795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EGX64_RS09800	COG1923	regulation of RNA biosynthetic process
EGX64_RS09805	COG0386	Belongs to the glutathione peroxidase family
EGX64_RS09810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGX64_RS09815	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EGX64_RS09820	COG0789	Transcriptional regulator
EGX64_RS09825	COG0174	glutamine synthetase
EGX64_RS09875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX64_RS09880	COG1131	(ABC) transporter
EGX64_RS09895	COG2197	response regulator
EGX64_RS09905	COG1525	nuclease
EGX64_RS09935	COG0527	aspartate kinase activity
EGX64_RS09940	COG0460	homoserine dehydrogenase
EGX64_RS09945	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EGX64_RS09950	COG0083	homoserine kinase activity
EGX64_RS09965	COG0833	amino acid
EGX64_RS09980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGX64_RS09985	COG0516	GMP reductase activity
EGX64_RS10000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGX64_RS10010	COG4224	UPF0291 protein
EGX64_RS10015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGX64_RS10025	COG4846	Membrane protein involved in cytochrome C biogenesis
EGX64_RS10030	COG0420	3'-5' exonuclease activity
EGX64_RS10035	COG0419	ATPase involved in DNA repair
EGX64_RS10040	COG1970	mechanosensitive ion channel activity
EGX64_RS10045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX64_RS10050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGX64_RS10055	COG0824	Thioesterase
EGX64_RS10065	COG4841	protein insertion into membrane
EGX64_RS10070	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EGX64_RS10075	COG0187	DNA topoisomerase II activity
EGX64_RS10080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX64_RS10085	COG1115	amino acid carrier protein
EGX64_RS10090	COG3711	transcriptional antiterminator
EGX64_RS10095	COG0628	permease
EGX64_RS10100	COG0392	lysyltransferase activity
EGX64_RS10100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EGX64_RS10115	COG1942	4-Oxalocrotonate Tautomerase
EGX64_RS10120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGX64_RS10125	COG0287	Prephenate dehydrogenase
EGX64_RS10130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGX64_RS10135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX64_RS10135	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX64_RS10140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX64_RS10145	COG0134	indole-3-glycerol-phosphate synthase activity
EGX64_RS10150	COG0135	phosphoribosylanthranilate isomerase activity
EGX64_RS10155	COG0133	tryptophan synthase activity
EGX64_RS10160	COG0159	tryptophan synthase activity
EGX64_RS10175	COG2348	transferase activity, transferring amino-acyl groups
EGX64_RS10180	COG2348	transferase activity, transferring amino-acyl groups
EGX64_RS10190	COG4607	ABC-type enterochelin transport system periplasmic component
EGX64_RS10220	COG1164	Oligoendopeptidase f
EGX64_RS10225	COG0704	Plays a role in the regulation of phosphate uptake
EGX64_RS10230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGX64_RS10235	COG0581	inorganic phosphate transmembrane transporter activity
EGX64_RS10240	COG0573	inorganic phosphate transmembrane transporter activity
EGX64_RS10245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGX64_RS10250	COG2996	Protein conserved in bacteria
EGX64_RS10255	COG0488	(ABC) transporter
EGX64_RS10260	COG0527	aspartate kinase activity
EGX64_RS10265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX64_RS10270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX64_RS10275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGX64_RS10280	COG2171	N-acyltransferase activity
EGX64_RS10285	COG1473	amidohydrolase
EGX64_RS10310	COG1278	Cold shock
EGX64_RS10320	COG1254	Belongs to the acylphosphatase family
EGX64_RS10330	COG3853	Toxic anion resistance protein (TelA)
EGX64_RS10335	COG1114	Component of the transport system for branched-chain amino acids
EGX64_RS10340	COG4548	von Willebrand factor, type A
EGX64_RS10345	COG0714	Associated with various cellular activities
EGX64_RS10370	COG1131	(ABC) transporter
EGX64_RS10375	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX64_RS10380	COG0567	Dehydrogenase, E1 component
EGX64_RS10390	COG5002	protein histidine kinase activity
EGX64_RS10395	COG0745	RESPONSE REGULATOR receiver
EGX64_RS10405	COG1349	DNA-binding transcription factor activity
EGX64_RS10410	COG0534	Mate efflux family protein
EGX64_RS10420	COG0395	ABC-type sugar transport system, permease component
EGX64_RS10430	COG4209	transmembrane transport
EGX64_RS10435	COG3842	ATPase activity
EGX64_RS10440	COG0671	phosphoesterase, PA-phosphatase related
EGX64_RS10445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGX64_RS10460	COG0793	Belongs to the peptidase S41A family
EGX64_RS10465	COG4479	Belongs to the UPF0346 family
EGX64_RS10470	COG2190	(PTS) system
EGX64_RS10475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGX64_RS10500	COG1136	(ABC) transporter
EGX64_RS10515	COG1413	lyase activity
EGX64_RS10525	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGX64_RS10535	COG4372	Transposase
EGX64_RS10535	COG1511	domain protein
EGX64_RS10535	COG1196	nuclear chromosome segregation
EGX64_RS10540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX64_RS10545	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EGX64_RS10555	COG0116	Belongs to the methyltransferase superfamily
EGX64_RS10565	COG3599	regulation of cell shape
EGX64_RS10570	COG4474	Belongs to the UPF0398 family
EGX64_RS10580	COG3331	DNA recombination
EGX64_RS10585	COG4499	WXG100 protein secretion system (Wss), protein YukC
EGX64_RS10585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX64_RS10595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX64_RS10600	COG3935	DnaD domain protein
EGX64_RS10605	COG0017	Asparaginyl-tRNA synthetase
EGX64_RS10610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGX64_RS10610	COG1199	ATP-dependent helicase activity
EGX64_RS10620	COG0617	tRNA 3'-terminal CCA addition
EGX64_RS10625	COG0438	transferase activity, transferring glycosyl groups
EGX64_RS10630	COG1694	Mazg nucleotide pyrophosphohydrolase
EGX64_RS10635	COG2738	Putative neutral zinc metallopeptidase
EGX64_RS10640	COG4347	Protein of unknown function (DUF1405)
EGX64_RS10645	COG5582	Belongs to the UPF0302 family
EGX64_RS10655	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGX64_RS10660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EGX64_RS10665	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EGX64_RS10670	COG0105	UTP biosynthetic process
EGX64_RS10675	COG0142	geranyltranstransferase activity
EGX64_RS10680	COG2226	methyltransferase
EGX64_RS10695	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EGX64_RS10700	COG1160	GTP binding
EGX64_RS10705	COG0539	negative regulation of cytoplasmic translation
EGX64_RS10710	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EGX64_RS10715	COG0252	asparaginase activity
EGX64_RS10720	COG0492	ferredoxin-NADP+ reductase activity
EGX64_RS10725	COG1388	LysM domain
EGX64_RS10730	COG0514	ATP-dependent DNA helicase (RecQ)
EGX64_RS10740	COG1141	Ferredoxin
EGX64_RS10760	COG0745	RESPONSE REGULATOR receiver
EGX64_RS10765	COG1187	pseudouridine synthase activity
EGX64_RS10770	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGX64_RS10775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EGX64_RS10780	COG1547	Domain of unknown function (DUF309)
EGX64_RS10785	COG4974	Belongs to the 'phage' integrase family
EGX64_RS10790	COG0735	belongs to the Fur family
EGX64_RS10795	COG0494	nUDIX hydrolase
EGX64_RS10800	COG0667	Aldo Keto reductase
EGX64_RS10805	COG1028	Short-chain dehydrogenase reductase Sdr
EGX64_RS10810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGX64_RS10815	COG1234	tRNA 3'-trailer cleavage
EGX64_RS10820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGX64_RS10835	COG0366	Alpha amylase catalytic
EGX64_RS10840	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EGX64_RS10845	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX64_RS10850	COG4129	membrane
EGX64_RS10860	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX64_RS10865	COG0022	dehydrogenase e1 component
EGX64_RS10870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGX64_RS10875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX64_RS10880	COG0497	DNA recombination
EGX64_RS10885	COG1438	arginine binding
EGX64_RS10895	COG1722	exodeoxyribonuclease VII activity
EGX64_RS10900	COG1570	exodeoxyribonuclease VII activity
EGX64_RS10905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGX64_RS10910	COG1302	Protein conserved in bacteria
EGX64_RS10915	COG0439	Biotin carboxylase
EGX64_RS10920	COG0511	ligase activity, forming carbon-carbon bonds
EGX64_RS10925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGX64_RS10930	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGX64_RS10935	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EGX64_RS10940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGX64_RS10945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EGX64_RS10950	COG0006	proline dipeptidase activity
EGX64_RS10965	COG0095	Lipoate-protein ligase
EGX64_RS10970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX64_RS10980	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGX64_RS10985	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGX64_RS10990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGX64_RS10995	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EGX64_RS11020	COG4537	Required for transformation and DNA binding
EGX64_RS11025	COG1459	type II secretion system
EGX64_RS11030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX64_RS11035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX64_RS11040	COG0011	TIGRFAM Protein of
EGX64_RS11045	COG1940	carbohydrate kinase activity
EGX64_RS11050	COG4483	Protein conserved in bacteria
EGX64_RS11055	COG0457	Tetratricopeptide repeat
EGX64_RS11055	COG0705	Rhomboid family
EGX64_RS11060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGX64_RS11065	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGX64_RS11070	COG0768	penicillin binding
EGX64_RS11080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGX64_RS11085	COG0735	belongs to the Fur family
EGX64_RS11090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX64_RS11095	COG1121	(ABC) transporter
EGX64_RS11100	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EGX64_RS11105	COG0513	Belongs to the DEAD box helicase family
EGX64_RS11110	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGX64_RS11115	COG2384	SAM-dependent methyltransferase
EGX64_RS11120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGX64_RS11125	COG0358	DNA primase activity
EGX64_RS11130	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EGX64_RS11135	COG0517	IMP dehydrogenase activity
EGX64_RS11140	COG0423	glycine-tRNA ligase activity
EGX64_RS11145	COG1381	Involved in DNA repair and RecF pathway recombination
EGX64_RS11150	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGX64_RS11155	COG0295	cytidine deaminase activity
EGX64_RS11160	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EGX64_RS11165	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EGX64_RS11170	COG1702	phosphate starvation-inducible protein PhoH
EGX64_RS11180	COG4864	UPF0365 protein
EGX64_RS11185	COG1030	water channel activity
EGX64_RS11195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGX64_RS11200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGX64_RS11205	COG2264	protein methyltransferase activity
EGX64_RS11210	COG0484	heat shock protein binding
EGX64_RS11215	COG0443	Heat shock 70 kDa protein
EGX64_RS11220	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGX64_RS11225	COG1420	regulation of RNA biosynthetic process
EGX64_RS11230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX64_RS11235	COG0481	GTPase activity
EGX64_RS11240	COG0268	Binds directly to 16S ribosomal RNA
EGX64_RS11255	COG1466	dna polymerase III delta subunit
EGX64_RS11260	COG2333	competence protein COMEC
EGX64_RS11260	COG0658	competence protein
EGX64_RS11265	COG2131	deaminase
EGX64_RS11275	COG2226	methyltransferase
EGX64_RS11280	COG0799	negative regulation of ribosome biogenesis
EGX64_RS11285	COG1713	HD superfamily hydrolase involved in NAD metabolism
EGX64_RS11290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EGX64_RS11295	COG1534	Rna-binding protein
EGX64_RS11300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGX64_RS11305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EGX64_RS11310	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EGX64_RS11315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGX64_RS11320	COG1914	H( )-stimulated, divalent metal cation uptake system
EGX64_RS11325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EGX64_RS11330	COG0439	Biotin carboxylase
EGX64_RS11335	COG0511	ligase activity, forming carbon-carbon bonds
EGX64_RS11340	COG1984	allophanate hydrolase subunit 2
EGX64_RS11345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGX64_RS11350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX64_RS11355	COG0572	uridine kinase
EGX64_RS11360	COG0826	peptidase U32
EGX64_RS11365	COG0826	peptidase U32
EGX64_RS11375	COG3906	Belongs to the UPF0473 family
EGX64_RS11380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGX64_RS11385	COG4472	Bacterial protein of unknown function (DUF965)
EGX64_RS11390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EGX64_RS11395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX64_RS11405	COG0482	sulfurtransferase activity
EGX64_RS11410	COG1104	cysteine desulfurase activity
EGX64_RS11415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX64_RS11430	COG1959	2 iron, 2 sulfur cluster binding
EGX64_RS11435	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGX64_RS11440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGX64_RS11450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EGX64_RS11455	COG0124	histidyl-tRNA synthetase
EGX64_RS11460	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX64_RS11465	COG1490	D-aminoacyl-tRNA deacylase activity
EGX64_RS11470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX64_RS11475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX64_RS11480	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EGX64_RS11480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGX64_RS11485	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX64_RS11485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX64_RS11490	COG1862	Preprotein translocase
EGX64_RS11495	COG0343	queuine tRNA-ribosyltransferase activity
EGX64_RS11500	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EGX64_RS11505	COG2255	four-way junction helicase activity
EGX64_RS11510	COG0632	four-way junction helicase activity
EGX64_RS11515	COG4492	Belongs to the UPF0735 family
EGX64_RS11520	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGX64_RS11525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EGX64_RS11530	COG2868	ribosomal protein
EGX64_RS11535	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EGX64_RS11565	COG2003	Belongs to the UPF0758 family
EGX64_RS11575	COG0285	dihydrofolate synthase activity
EGX64_RS11580	COG0525	valine-tRNA ligase activity
EGX64_RS11585	COG2818	Glycosylase
EGX64_RS11595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGX64_RS11600	COG0113	porphobilinogen synthase activity
EGX64_RS11610	COG0181	hydroxymethylbilane synthase activity
EGX64_RS11620	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EGX64_RS11625	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EGX64_RS11630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EGX64_RS11635	COG0544	peptidyl-prolyl cis-trans isomerase activity
EGX64_RS11645	COG4112	unkown
EGX64_RS11650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EGX64_RS11655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EGX64_RS11660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EGX64_RS11665	COG0833	amino acid
EGX64_RS11670	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EGX64_RS11675	COG1484	DNA-dependent DNA replication
EGX64_RS11680	COG3611	Membrane attachment protein
EGX64_RS11685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EGX64_RS11695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGX64_RS11705	COG0237	dephospho-CoA kinase activity
EGX64_RS11710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGX64_RS11715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX64_RS11715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX64_RS11720	COG5002	protein histidine kinase activity
EGX64_RS11725	COG0745	RESPONSE REGULATOR receiver
EGX64_RS11730	COG0538	isocitrate dehydrogenase activity
EGX64_RS11735	COG0372	Belongs to the citrate synthase family
EGX64_RS11740	COG1113	amino acid transport
EGX64_RS11745	COG0469	pyruvate kinase activity
EGX64_RS11750	COG0205	6-phosphofructokinase activity
EGX64_RS11755	COG0825	malonyl-CoA metabolic process
EGX64_RS11760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EGX64_RS11765	COG0281	malic enzyme
EGX64_RS11770	COG0587	DNA-directed DNA polymerase activity
EGX64_RS11775	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EGX64_RS11780	COG4109	DRTGG domain
EGX64_RS11790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EGX64_RS11795	COG0006	proline dipeptidase activity
EGX64_RS11800	COG0686	Belongs to the AlaDH PNT family
EGX64_RS11805	COG0589	response to stress
EGX64_RS11810	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGX64_RS11815	COG0827	DNA restriction-modification system
EGX64_RS11820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EGX64_RS11830	COG0301	tRNA thio-modification
EGX64_RS11840	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EGX64_RS11845	COG1956	GAF domain-containing protein
EGX64_RS11855	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGX64_RS11860	COG0584	glycerophosphoryl diester phosphodiesterase
EGX64_RS11865	COG1764	response to oxidative stress
EGX64_RS11870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EGX64_RS11875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGX64_RS11885	COG1263	PTS System
EGX64_RS11885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX64_RS11890	COG0204	Acyl-transferase
EGX64_RS11895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX64_RS11900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGX64_RS11915	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EGX64_RS11920	COG1609	Transcriptional regulator
EGX64_RS11925	COG1605	Chorismate mutase
EGX64_RS11925	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EGX64_RS11935	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EGX64_RS11940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGX64_RS11945	COG1674	ftsk spoiiie
EGX64_RS11950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX64_RS11955	COG4848	Belongs to the UPF0354 family
EGX64_RS11960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX64_RS11965	COG1363	Peptidase, m42
EGX64_RS11975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGX64_RS11980	COG0510	thiamine kinase activity
EGX64_RS11985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX64_RS11990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGX64_RS12000	COG1187	pseudouridine synthase activity
EGX64_RS12005	COG2244	polysaccharide biosynthetic process
EGX64_RS12010	COG2081	HI0933 family
EGX64_RS12025	COG0495	leucyl-tRNA aminoacylation
EGX64_RS12030	COG2814	Major facilitator Superfamily
EGX64_RS12035	COG1242	4 iron, 4 sulfur cluster binding
EGX64_RS12040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EGX64_RS12050	COG2267	carboxylic ester hydrolase activity
EGX64_RS12055	COG0506	proline dehydrogenase activity
EGX64_RS12060	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EGX64_RS12065	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX64_RS12065	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX64_RS12075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX64_RS12075	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX64_RS12085	COG5632	N-Acetylmuramoyl-L-alanine amidase
EGX64_RS12085	COG4193	domain, Protein
EGX64_RS12085	COG3266	domain, Protein
EGX64_RS12115	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGX64_RS12125	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX64_RS12130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX64_RS12135	COG0656	L-ascorbic acid biosynthetic process
EGX64_RS12145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EGX64_RS12150	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EGX64_RS12155	COG1506	peptidase
EGX64_RS12160	COG0494	nUDIX hydrolase
EGX64_RS12165	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EGX64_RS12175	COG0318	PFAM AMP-dependent synthetase and ligase
EGX64_RS12245	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EGX64_RS12250	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGX64_RS12255	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EGX64_RS12260	COG2329	Antibiotic biosynthesis monooxygenase
EGX64_RS12270	COG4473	ABC transporter
EGX64_RS12275	COG1131	(ABC) transporter
EGX64_RS12280	COG0537	adenosine 5'-monophosphoramidase activity
EGX64_RS12295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX64_RS12305	COG3481	metal-dependent phosphohydrolase, HD sub domain
EGX64_RS12315	COG0420	3'-5' exonuclease activity
EGX64_RS12320	COG3679	Belongs to the UPF0342 family
EGX64_RS12325	COG4399	Belongs to the UPF0754 family
EGX64_RS12335	COG2197	response regulator
EGX64_RS12340	COG4585	Histidine kinase
EGX64_RS12340	COG2203	Gaf domain
EGX64_RS12345	COG0564	pseudouridine synthase activity
EGX64_RS12355	COG0114	fumarate hydratase activity
EGX64_RS12380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGX64_RS12385	COG1126	abc transporter atp-binding protein
EGX64_RS12555	COG0735	belongs to the Fur family
EGX64_RS12560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX64_RS12565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGX64_RS12570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGX64_RS12575	COG4129	membrane
EGX64_RS12585	COG3557	Belongs to the UPF0374 family
EGX64_RS12595	COG1988	membrane-bound metal-dependent
EGX64_RS12605	COG1134	teichoic acid transport
EGX64_RS12605	COG1388	LysM domain
EGX64_RS12615	COG2137	regulation of response to DNA damage stimulus
EGX64_RS12620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX64_RS12625	COG0693	protein deglycase activity
EGX64_RS12635	COG0535	radical SAM domain protein
EGX64_RS12640	COG1607	acyl-coa hydrolase
EGX64_RS12645	COG2309	aminopeptidase activity
EGX64_RS12650	COG4840	Belongs to the UPF0435 family
EGX64_RS12655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX64_RS12665	COG1295	ribonuclease BN
EGX64_RS12670	COG2197	response regulator
EGX64_RS12675	COG4585	Histidine kinase
EGX64_RS12690	COG0024	Methionine aminopeptidase
EGX64_RS12695	COG4129	membrane
EGX64_RS12715	COG1528	Iron-storage protein
EGX64_RS12725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGX64_RS12735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGX64_RS12740	COG1597	lipid kinase activity