locus-tag	class	description
MUA70_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MUA70_RS00010	COG0592	DNA-directed DNA polymerase activity
MUA70_RS00015	COG2501	S4 domain
MUA70_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MUA70_RS00025	COG0187	DNA topoisomerase II activity
MUA70_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MUA70_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MUA70_RS00040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MUA70_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MUA70_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MUA70_RS00075	COG0359	binds to the 23S rRNA
MUA70_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
MUA70_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MUA70_RS00100	COG0745	RESPONSE REGULATOR receiver
MUA70_RS00105	COG5002	protein histidine kinase activity
MUA70_RS00110	COG4863	YycH protein
MUA70_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MUA70_RS00125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MUA70_RS00130	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MUA70_RS00165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MUA70_RS00220	COG3425	synthase
MUA70_RS00225	COG0584	glycerophosphoryl diester phosphodiesterase
MUA70_RS00230	COG2030	dehydratase
MUA70_RS00275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MUA70_RS00300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MUA70_RS00300	COG1199	ATP-dependent helicase activity
MUA70_RS00350	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MUA70_RS00370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUA70_RS00500	COG1388	LysM domain
MUA70_RS00505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUA70_RS00510	COG2210	Belongs to the sulfur carrier protein TusA family
MUA70_RS00515	COG1937	Protein conserved in bacteria
MUA70_RS00520	COG0730	response to heat
MUA70_RS00525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA70_RS00530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MUA70_RS00555	COG0640	Transcriptional regulator
MUA70_RS00560	COG0701	Predicted permease
MUA70_RS00580	COG0668	transmembrane transport
MUA70_RS00615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MUA70_RS00620	COG0579	oxidoreductase
MUA70_RS00630	COG1755	Isoprenylcysteine carboxyl methyltransferase
MUA70_RS00695	COG0201	protein transport
MUA70_RS00705	COG1073	alpha beta
MUA70_RS00715	COG0653	protein targeting
MUA70_RS00720	COG0438	transferase activity, transferring glycosyl groups
MUA70_RS00735	COG1131	(ABC) transporter
MUA70_RS00750	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MUA70_RS00755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MUA70_RS00760	COG0156	8-amino-7-oxononanoate synthase activity
MUA70_RS00765	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MUA70_RS00790	COG0523	cobalamin synthesis protein
MUA70_RS00805	COG0803	Belongs to the bacterial solute-binding protein 9 family
MUA70_RS00815	COG0431	NADPH-dependent FMN reductase
MUA70_RS00815	COG1053	succinate dehydrogenase
MUA70_RS00815	COG3976	FMN-binding domain protein
MUA70_RS00825	COG1028	Short-chain dehydrogenase reductase Sdr
MUA70_RS00875	COG0601	transmembrane transport
MUA70_RS00885	COG0444	Belongs to the ABC transporter superfamily
MUA70_RS00890	COG1124	(ABC) transporter
MUA70_RS00900	COG1882	Formate acetyltransferase
MUA70_RS00905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MUA70_RS00910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA70_RS00915	COG1114	Component of the transport system for branched-chain amino acids
MUA70_RS00920	COG1309	transcriptional regulator
MUA70_RS00925	COG3246	L-lysine catabolic process to acetate
MUA70_RS00930	COG1250	3-hydroxyacyl-CoA dehydrogenase
MUA70_RS00965	COG1288	antiporter activity
MUA70_RS00970	COG0549	Belongs to the carbamate kinase family
MUA70_RS00975	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUA70_RS00985	COG0346	lactoylglutathione lyase activity
MUA70_RS00990	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MUA70_RS00995	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MUA70_RS01005	COG2376	Dihydroxyacetone kinase
MUA70_RS01010	COG1461	Dihydroxyacetone kinase
MUA70_RS01015	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
MUA70_RS01035	COG2814	Major facilitator Superfamily
MUA70_RS01060	COG2814	Major facilitator Superfamily
MUA70_RS01075	COG2962	Rard protein
MUA70_RS01080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MUA70_RS01085	COG0471	metal ion transport
MUA70_RS01090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUA70_RS01095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MUA70_RS01100	COG0022	dehydrogenase e1 component
MUA70_RS01105	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUA70_RS01125	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MUA70_RS01130	COG1054	Belongs to the UPF0176 family
MUA70_RS01135	COG3386	PFAM SMP-30 Gluconolaconase
MUA70_RS01140	COG2353	YceI-like domain
MUA70_RS01145	COG0579	oxidoreductase
MUA70_RS01170	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MUA70_RS01175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MUA70_RS01180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MUA70_RS01190	COG0131	Imidazoleglycerol-phosphate dehydratase
MUA70_RS01195	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MUA70_RS01200	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MUA70_RS01205	COG0107	imidazoleglycerol-phosphate synthase activity
MUA70_RS01210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MUA70_RS01210	COG0140	phosphoribosyl-ATP diphosphatase activity
MUA70_RS01215	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MUA70_RS01220	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MUA70_RS01230	COG2814	Major facilitator Superfamily
MUA70_RS01235	COG0737	Belongs to the 5'-nucleotidase family
MUA70_RS01250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MUA70_RS01255	COG3639	organic phosphonate transmembrane transporter activity
MUA70_RS01280	COG0653	protein targeting
MUA70_RS01310	COG2814	Major facilitator Superfamily
MUA70_RS01315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MUA70_RS01325	COG1764	response to oxidative stress
MUA70_RS01335	COG1705	Flagellar rod assembly protein muramidase FlgJ
MUA70_RS01335	COG3942	CHAP domain
MUA70_RS01345	COG1482	cell wall glycoprotein biosynthetic process
MUA70_RS01350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA70_RS01350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA70_RS01350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA70_RS01355	COG3711	transcriptional antiterminator
MUA70_RS01355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA70_RS01390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA70_RS01395	COG3227	Zinc metalloprotease (Elastase)
MUA70_RS01400	COG1438	arginine binding
MUA70_RS01405	COG2235	arginine
MUA70_RS01410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MUA70_RS01420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MUA70_RS01430	COG2843	Capsule synthesis protein
MUA70_RS01435	COG3961	Belongs to the TPP enzyme family
MUA70_RS01450	COG1388	LysM domain
MUA70_RS01450	COG3942	CHAP domain
MUA70_RS01610	COG0640	Transcriptional regulator
MUA70_RS01620	COG2226	methyltransferase
MUA70_RS01640	COG4195	phage-related replication protein
MUA70_RS01650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA70_RS01655	COG0702	epimerase
MUA70_RS01660	COG1785	Belongs to the alkaline phosphatase family
MUA70_RS01675	COG2205	protein histidine kinase activity
MUA70_RS01680	COG1136	(ABC) transporter
MUA70_RS01720	COG1846	Transcriptional regulator
MUA70_RS01730	COG0386	Belongs to the glutathione peroxidase family
MUA70_RS01735	COG0175	sulfate reduction
MUA70_RS01740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MUA70_RS01745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUA70_RS01760	COG0730	response to heat
MUA70_RS01765	COG2046	Belongs to the sulfate adenylyltransferase family
MUA70_RS01770	COG0529	Catalyzes the synthesis of activated sulfate
MUA70_RS01780	COG1328	CTP reductase activity
MUA70_RS01785	COG0602	queuosine metabolic process
MUA70_RS01790	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MUA70_RS01800	COG1510	regulation of RNA biosynthetic process
MUA70_RS01805	COG1012	belongs to the aldehyde dehydrogenase family
MUA70_RS01810	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MUA70_RS01825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MUA70_RS01830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUA70_RS01830	COG0574	Belongs to the PEP-utilizing enzyme family
MUA70_RS01835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MUA70_RS01840	COG0579	oxidoreductase
MUA70_RS01850	COG3588	fructose-bisphosphate aldolase
MUA70_RS01855	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUA70_RS01885	COG0531	amino acid
MUA70_RS01890	COG0583	DNA-binding transcription factor activity
MUA70_RS01895	COG0039	L-malate dehydrogenase activity
MUA70_RS01900	COG0028	Belongs to the TPP enzyme family
MUA70_RS01905	COG3527	Alpha-acetolactate decarboxylase
MUA70_RS01915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MUA70_RS01920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MUA70_RS01925	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MUA70_RS01940	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MUA70_RS01950	COG0167	dihydroorotate dehydrogenase activity
MUA70_RS01955	COG3001	Fructosamine kinase
MUA70_RS01960	COG1113	amino acid transport
MUA70_RS01975	COG0741	lytic transglycosylase activity
MUA70_RS01990	COG3942	CHAP domain
MUA70_RS01995	COG0436	Aminotransferase
MUA70_RS02005	COG2608	mercury ion transmembrane transporter activity
MUA70_RS02010	COG2217	Heavy metal translocating P-type atpase
MUA70_RS02020	COG1028	Short-chain dehydrogenase reductase Sdr
MUA70_RS02025	COG1012	belongs to the aldehyde dehydrogenase family
MUA70_RS02050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MUA70_RS02055	COG3425	synthase
MUA70_RS02075	COG0583	DNA-binding transcription factor activity
MUA70_RS02080	COG1380	Effector of murein hydrolase LrgA
MUA70_RS02085	COG1346	cytolysis
MUA70_RS02090	COG0028	Belongs to the TPP enzyme family
MUA70_RS02095	COG1263	PTS System
MUA70_RS02095	COG2190	(PTS) system
MUA70_RS02095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA70_RS02100	COG1266	CAAX protease self-immunity
MUA70_RS02105	COG1063	alcohol dehydrogenase
MUA70_RS02110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA70_RS02115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MUA70_RS02130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MUA70_RS02140	COG2843	Capsule synthesis protein
MUA70_RS02155	COG4975	Glucose uptake
MUA70_RS02160	COG1869	D-ribose catabolic process
MUA70_RS02170	COG1070	Carbohydrate kinase
MUA70_RS02185	COG1760	l-serine dehydratase
MUA70_RS02190	COG1760	l-serine dehydratase
MUA70_RS02205	COG3764	Sortase (surface protein transpeptidase)
MUA70_RS02215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA70_RS02225	COG1012	belongs to the aldehyde dehydrogenase family
MUA70_RS02235	COG2514	catechol 2,3-dioxygenase activity
MUA70_RS02250	COG1012	belongs to the aldehyde dehydrogenase family
MUA70_RS02255	COG3949	Membrane
MUA70_RS02265	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
MUA70_RS02270	COG0586	Pfam SNARE associated Golgi protein
MUA70_RS02275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MUA70_RS02280	COG2022	thiamine diphosphate biosynthetic process
MUA70_RS02290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MUA70_RS02300	COG2271	Major facilitator Superfamily
MUA70_RS02315	COG4876	unkown
MUA70_RS02320	COG2357	RelA SpoT domain protein
MUA70_RS02340	COG0789	Transcriptional regulator
MUA70_RS02345	COG2271	Major facilitator Superfamily
MUA70_RS02350	COG1802	Transcriptional regulator
MUA70_RS02360	COG2610	gluconate transmembrane transporter activity
MUA70_RS02365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MUA70_RS02370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUA70_RS02375	COG0438	transferase activity, transferring glycosyl groups
MUA70_RS02380	COG0494	nUDIX hydrolase
MUA70_RS02385	COG0556	nucleotide-excision repair
MUA70_RS02400	COG4221	oxidoreductase activity
MUA70_RS02405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA70_RS02410	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MUA70_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
MUA70_RS02430	COG1363	Peptidase, m42
MUA70_RS02440	COG0069	glutamate synthase activity
MUA70_RS02455	COG4619	ABC transporter
MUA70_RS02460	COG0390	transport system, permease component
MUA70_RS02465	COG2814	Major facilitator Superfamily
MUA70_RS02470	COG2272	Belongs to the type-B carboxylesterase lipase family
MUA70_RS02475	COG0531	amino acid
MUA70_RS02480	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
MUA70_RS02485	COG1063	alcohol dehydrogenase
MUA70_RS02505	COG1174	glycine betaine transport
MUA70_RS02510	COG1346	cytolysis
MUA70_RS02515	COG1380	Effector of murein hydrolase LrgA
MUA70_RS02520	COG3279	Response regulator of the LytR AlgR family
MUA70_RS02525	COG3275	phosphorelay sensor kinase activity
MUA70_RS02535	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MUA70_RS02540	COG0706	membrane insertase activity
MUA70_RS02550	COG0531	amino acid
MUA70_RS02555	COG1113	amino acid transport
MUA70_RS02580	COG1929	Belongs to the glycerate kinase type-1 family
MUA70_RS02595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MUA70_RS02600	COG0588	phosphoglycerate mutase activity
MUA70_RS02610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MUA70_RS02615	COG0765	amino acid transport
MUA70_RS02620	COG1126	abc transporter atp-binding protein
MUA70_RS02630	COG2348	transferase activity, transferring amino-acyl groups
MUA70_RS02650	COG2116	formate transmembrane transporter activity
MUA70_RS02655	COG0454	-acetyltransferase
MUA70_RS02670	COG0747	negative chemotaxis
MUA70_RS02690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MUA70_RS02695	COG2146	nitrite reductase [NAD(P)H] activity
MUA70_RS02705	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MUA70_RS02710	COG1140	nitrate reductase beta subunit
MUA70_RS02720	COG2181	nitrate reductase activity
MUA70_RS02730	COG4585	Histidine kinase
MUA70_RS02735	COG2197	response regulator
MUA70_RS02740	COG2223	nitrite transmembrane transporter activity
MUA70_RS02745	COG1846	Transcriptional regulator
MUA70_RS02750	COG0778	Nitroreductase
MUA70_RS02770	COG3871	stress protein (general stress protein 26)
MUA70_RS02785	COG1263	PTS System
MUA70_RS02785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA70_RS02815	COG0604	alcohol dehydrogenase
MUA70_RS02820	COG0456	acetyltransferase
MUA70_RS02825	COG0463	Glycosyl transferase, family 2
MUA70_RS02825	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA70_RS02835	COG0463	Glycosyl transferase, family 2
MUA70_RS02835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA70_RS02840	COG1620	l-lactate permease
MUA70_RS02850	COG0579	oxidoreductase
MUA70_RS02855	COG3850	Histidine kinase
MUA70_RS02855	COG5002	protein histidine kinase activity
MUA70_RS02860	COG0745	RESPONSE REGULATOR receiver
MUA70_RS02865	COG0577	efflux transmembrane transporter activity
MUA70_RS02870	COG1136	(ABC) transporter
MUA70_RS02885	COG4640	response to antibiotic
MUA70_RS02890	COG2814	Major facilitator Superfamily
MUA70_RS02900	COG1566	PFAM secretion protein HlyD family protein
MUA70_RS02905	COG2814	Major facilitator Superfamily
MUA70_RS02915	COG0657	acetylesterase activity
MUA70_RS02935	COG1304	FMN binding
MUA70_RS02940	COG0786	glutamate:sodium symporter activity
MUA70_RS02965	COG2094	Belongs to the DNA glycosylase MPG family
MUA70_RS02975	COG1069	ribulokinase activity
MUA70_RS02980	COG2017	converts alpha-aldose to the beta-anomer
MUA70_RS02985	COG2258	MOSC domain
MUA70_RS02990	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MUA70_RS03000	COG1266	CAAX protease self-immunity
MUA70_RS03005	COG0010	Belongs to the arginase family
MUA70_RS03010	COG1473	amidohydrolase
MUA70_RS03015	COG1028	Short-chain dehydrogenase reductase Sdr
MUA70_RS03020	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MUA70_RS03040	COG1737	Transcriptional regulator
MUA70_RS03045	COG1263	PTS System
MUA70_RS03045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA70_RS03055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MUA70_RS03075	COG1113	amino acid transport
MUA70_RS03085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA70_RS03085	COG1263	PTS System
MUA70_RS03090	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MUA70_RS03105	COG1266	CAAX protease self-immunity
MUA70_RS03115	COG0483	inositol monophosphate 1-phosphatase activity
MUA70_RS03120	COG1316	TRANSCRIPTIONal
MUA70_RS03150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA70_RS03155	COG2076	Multidrug Resistance protein
MUA70_RS03160	COG2076	Multidrug Resistance protein
MUA70_RS03165	COG3942	CHAP domain
MUA70_RS03180	COG1757	Na H antiporter
MUA70_RS03185	COG3942	CHAP domain
MUA70_RS03210	COG0829	nickel cation binding
MUA70_RS03215	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MUA70_RS03220	COG0830	nickel cation binding
MUA70_RS03225	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MUA70_RS03230	COG0804	urea catabolic process
MUA70_RS03235	COG0832	Belongs to the urease beta subunit family
MUA70_RS03240	COG0831	urea catabolic process
MUA70_RS03250	COG1960	acyl-CoA dehydrogenase activity
MUA70_RS03260	COG1268	BioY protein
MUA70_RS03270	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MUA70_RS03275	COG0725	ABC transporter, periplasmic molybdate-binding protein
MUA70_RS03280	COG4149	molybdate abc transporter
MUA70_RS03285	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MUA70_RS03290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MUA70_RS03295	COG0521	Mo-molybdopterin cofactor biosynthetic process
MUA70_RS03300	COG0315	cyclic pyranopterin monophosphate synthase activity
MUA70_RS03305	COG0303	'Molybdopterin
MUA70_RS03315	COG0314	molybdopterin synthase activity
MUA70_RS03325	COG0746	molybdenum cofactor guanylyltransferase activity
MUA70_RS03330	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MUA70_RS03340	COG2814	Major facilitator Superfamily
MUA70_RS03360	COG2348	transferase activity, transferring amino-acyl groups
MUA70_RS03365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MUA70_RS03385	COG1028	Short-chain dehydrogenase reductase Sdr
MUA70_RS03390	COG4975	Glucose uptake
MUA70_RS03395	COG0551	DNA topoisomerase type I activity
MUA70_RS03395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUA70_RS03400	COG2252	PERMEase
MUA70_RS03415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MUA70_RS03420	COG0088	Forms part of the polypeptide exit tunnel
MUA70_RS03425	COG0089	rRNA binding
MUA70_RS03430	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MUA70_RS03435	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MUA70_RS03445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MUA70_RS03450	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MUA70_RS03460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MUA70_RS03465	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MUA70_RS03470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MUA70_RS03475	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MUA70_RS03480	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MUA70_RS03485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MUA70_RS03490	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MUA70_RS03495	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MUA70_RS03500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MUA70_RS03505	COG1841	ribosomal large subunit assembly
MUA70_RS03510	COG0200	Binds to the 23S rRNA
MUA70_RS03515	COG0201	protein transport
MUA70_RS03520	COG0563	adenylate kinase activity
MUA70_RS03525	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MUA70_RS03530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MUA70_RS03535	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MUA70_RS03540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MUA70_RS03545	COG0202	RNA polymerase activity
MUA70_RS03550	COG0203	ribosomal protein L17
MUA70_RS03555	COG1122	ATPase activity
MUA70_RS03560	COG1122	ATPase activity
MUA70_RS03570	COG0101	tRNA pseudouridine synthase activity
MUA70_RS03575	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MUA70_RS03580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MUA70_RS03585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MUA70_RS03590	COG1349	DNA-binding transcription factor activity
MUA70_RS03600	COG0698	ribose 5-phosphate isomerase
MUA70_RS03605	COG0698	ribose 5-phosphate isomerase
MUA70_RS03610	COG1105	Belongs to the carbohydrate kinase PfkB family
MUA70_RS03615	COG3684	Belongs to the aldolase LacD family
MUA70_RS03620	COG1447	Phosphotransferase system cellobiose-specific component IIA
MUA70_RS03625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MUA70_RS03625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MUA70_RS03630	COG2723	6-phospho-beta-galactosidase activity
MUA70_RS03640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUA70_RS03645	COG2130	NADP-dependent
MUA70_RS03650	COG0604	alcohol dehydrogenase
MUA70_RS03665	COG1302	Protein conserved in bacteria
MUA70_RS03670	COG4264	IucA IucC family
MUA70_RS03675	COG2814	Major facilitator Superfamily
MUA70_RS03680	COG4264	IucA IucC family
MUA70_RS03685	COG3457	Alanine racemase
MUA70_RS03690	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MUA70_RS03695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA70_RS03700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA70_RS03705	COG3314	Sporulation integral membrane protein YlbJ
MUA70_RS03710	COG2329	Antibiotic biosynthesis monooxygenase
MUA70_RS03720	COG1988	membrane-bound metal-dependent
MUA70_RS03725	COG4284	Utp--glucose-1-phosphate uridylyltransferase
MUA70_RS03745	COG2814	Major facilitator Superfamily
MUA70_RS03750	COG0489	protein tyrosine kinase activity
MUA70_RS03800	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MUA70_RS03810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MUA70_RS03815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MUA70_RS03820	COG0561	phosphatase activity
MUA70_RS03840	COG0640	Transcriptional regulator
MUA70_RS03845	COG0702	epimerase
MUA70_RS03850	COG1482	cell wall glycoprotein biosynthetic process
MUA70_RS03870	COG0783	Belongs to the Dps family
MUA70_RS03875	COG0813	purine-nucleoside phosphorylase activity
MUA70_RS03880	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MUA70_RS03885	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MUA70_RS03890	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MUA70_RS03900	COG1854	S-ribosylhomocysteine lyase activity
MUA70_RS03920	COG5146	pantothenate kinase activity
MUA70_RS03930	COG3343	RNA polymerase activity
MUA70_RS03935	COG0504	CTP synthase activity
MUA70_RS03945	COG0191	fructose-bisphosphate aldolase activity
MUA70_RS03950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUA70_RS03955	COG1012	belongs to the aldehyde dehydrogenase family
MUA70_RS03960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MUA70_RS03965	COG0254	rRNA binding
MUA70_RS03970	COG1435	thymidine kinase activity
MUA70_RS03975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MUA70_RS03980	COG2890	protein-(glutamine-N5) methyltransferase activity
MUA70_RS03985	COG0009	L-threonylcarbamoyladenylate synthase
MUA70_RS03990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA70_RS03995	COG4475	Protein of unknown function (DUF436)
MUA70_RS04000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MUA70_RS04005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MUA70_RS04010	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MUA70_RS04020	COG0356	it plays a direct role in the translocation of protons across the membrane
MUA70_RS04030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MUA70_RS04035	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MUA70_RS04040	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MUA70_RS04045	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MUA70_RS04050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MUA70_RS04055	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MUA70_RS04065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MUA70_RS04070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MUA70_RS04080	COG0629	single-stranded DNA binding
MUA70_RS04085	COG1388	LysM domain
MUA70_RS04090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MUA70_RS04100	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MUA70_RS04105	COG0352	thiamine-phosphate diphosphorylase activity
MUA70_RS04110	COG0706	membrane insertase activity
MUA70_RS04115	COG1418	mRNA catabolic process
MUA70_RS04120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUA70_RS04125	COG1937	Protein conserved in bacteria
MUA70_RS04140	COG0772	Belongs to the SEDS family
MUA70_RS04145	COG1181	Belongs to the D-alanine--D-alanine ligase family
MUA70_RS04150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MUA70_RS04155	COG0513	Belongs to the DEAD box helicase family
MUA70_RS04165	COG3428	Bacterial PH domain
MUA70_RS04170	COG3402	PFAM membrane-flanked domain
MUA70_RS04175	COG0736	holo-[acyl-carrier-protein] synthase activity
MUA70_RS04180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MUA70_RS04190	COG2337	Toxic component of a toxin-antitoxin (TA) module
MUA70_RS04195	COG2208	phosphoserine phosphatase activity
MUA70_RS04210	COG1191	sigma factor activity
MUA70_RS04215	COG2183	response to ionizing radiation
MUA70_RS04220	COG3091	SprT-like family
MUA70_RS04250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MUA70_RS04255	COG0066	3-isopropylmalate dehydratase activity
MUA70_RS04260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MUA70_RS04265	COG0473	3-isopropylmalate dehydrogenase activity
MUA70_RS04270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MUA70_RS04275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MUA70_RS04285	COG0028	Belongs to the TPP enzyme family
MUA70_RS04290	COG0129	dihydroxy-acid dehydratase activity
MUA70_RS04295	COG0802	atpase or kinase
MUA70_RS04300	COG1214	PFAM Peptidase M22, glycoprotease
MUA70_RS04305	COG0456	acetyltransferase
MUA70_RS04310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MUA70_RS04320	COG0488	(ABC) transporter
MUA70_RS04325	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MUA70_RS04335	COG2391	methyltransferase activity
MUA70_RS04340	COG0425	Belongs to the sulfur carrier protein TusA family
MUA70_RS04345	COG0004	ammonium transporteR
MUA70_RS04350	COG1609	Transcriptional regulator
MUA70_RS04355	COG1621	beta-fructofuranosidase activity
MUA70_RS04360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MUA70_RS04365	COG3279	Response regulator of the LytR AlgR family
MUA70_RS04370	COG3290	protein histidine kinase activity
MUA70_RS04405	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MUA70_RS04410	COG0459	protein refolding
MUA70_RS04460	COG1725	Transcriptional regulator
MUA70_RS04465	COG1131	(ABC) transporter
MUA70_RS04475	COG1131	(ABC) transporter
MUA70_RS04520	COG2706	6-phosphogluconolactonase activity
MUA70_RS04525	COG1012	belongs to the aldehyde dehydrogenase family
MUA70_RS04530	COG1227	inorganic diphosphatase activity
MUA70_RS04535	COG1335	isochorismatase
MUA70_RS04550	COG0077	Prephenate dehydratase
MUA70_RS04560	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MUA70_RS04565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MUA70_RS04570	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MUA70_RS04580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MUA70_RS04585	COG4496	protein, YerC YecD
MUA70_RS04590	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MUA70_RS04595	COG0210	DNA helicase
MUA70_RS04600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MUA70_RS04605	COG4851	CamS sex pheromone cAM373 precursor
MUA70_RS04610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MUA70_RS04615	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUA70_RS04620	COG0154	amidase activity
MUA70_RS04625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MUA70_RS04630	COG1597	lipid kinase activity
MUA70_RS04635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MUA70_RS04645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUA70_RS04655	COG1528	Iron-storage protein
MUA70_RS04675	COG4129	membrane
MUA70_RS04680	COG0024	Methionine aminopeptidase
MUA70_RS04695	COG4585	Histidine kinase
MUA70_RS04700	COG2197	response regulator
MUA70_RS04705	COG1295	ribonuclease BN
MUA70_RS04715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA70_RS04720	COG4840	Belongs to the UPF0435 family
MUA70_RS04725	COG2309	aminopeptidase activity
MUA70_RS04730	COG1607	acyl-coa hydrolase
MUA70_RS04735	COG0535	radical SAM domain protein
MUA70_RS04745	COG0693	protein deglycase activity
MUA70_RS04750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUA70_RS04755	COG2137	regulation of response to DNA damage stimulus
MUA70_RS04765	COG1134	teichoic acid transport
MUA70_RS04765	COG1388	LysM domain
MUA70_RS04775	COG1988	membrane-bound metal-dependent
MUA70_RS04785	COG3557	Belongs to the UPF0374 family
MUA70_RS04795	COG4129	membrane
MUA70_RS04800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUA70_RS04805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MUA70_RS04810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MUA70_RS04815	COG0735	belongs to the Fur family
MUA70_RS04985	COG0765	amino acid transport
MUA70_RS04990	COG1126	abc transporter atp-binding protein
MUA70_RS04995	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MUA70_RS05020	COG0114	fumarate hydratase activity
MUA70_RS05030	COG0564	pseudouridine synthase activity
MUA70_RS05035	COG4585	Histidine kinase
MUA70_RS05035	COG2203	Gaf domain
MUA70_RS05040	COG2197	response regulator
MUA70_RS05050	COG4399	Belongs to the UPF0754 family
MUA70_RS05055	COG3679	Belongs to the UPF0342 family
MUA70_RS05060	COG0420	3'-5' exonuclease activity
MUA70_RS05070	COG3481	metal-dependent phosphohydrolase, HD sub domain
MUA70_RS05080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MUA70_RS05095	COG0537	adenosine 5'-monophosphoramidase activity
MUA70_RS05100	COG1131	(ABC) transporter
MUA70_RS05105	COG4473	ABC transporter
MUA70_RS05115	COG2329	Antibiotic biosynthesis monooxygenase
MUA70_RS05120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MUA70_RS05125	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MUA70_RS05130	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MUA70_RS05200	COG0318	PFAM AMP-dependent synthetase and ligase
MUA70_RS05210	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MUA70_RS05215	COG0494	nUDIX hydrolase
MUA70_RS05220	COG1506	peptidase
MUA70_RS05225	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MUA70_RS05230	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MUA70_RS05240	COG0656	L-ascorbic acid biosynthetic process
MUA70_RS05245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MUA70_RS05250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MUA70_RS05260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MUA70_RS05285	COG5632	N-Acetylmuramoyl-L-alanine amidase
MUA70_RS05285	COG4193	domain, Protein
MUA70_RS05285	COG3266	domain, Protein
MUA70_RS05295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUA70_RS05295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MUA70_RS05300	COG0307	riboflavin synthase, alpha
MUA70_RS05305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUA70_RS05305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MUA70_RS05310	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MUA70_RS05315	COG0506	proline dehydrogenase activity
MUA70_RS05320	COG2267	carboxylic ester hydrolase activity
MUA70_RS05330	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MUA70_RS05335	COG1242	4 iron, 4 sulfur cluster binding
MUA70_RS05340	COG2814	Major facilitator Superfamily
MUA70_RS05345	COG0495	leucyl-tRNA aminoacylation
MUA70_RS05360	COG2081	HI0933 family
MUA70_RS05365	COG2244	polysaccharide biosynthetic process
MUA70_RS05370	COG1187	pseudouridine synthase activity
MUA70_RS05380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MUA70_RS05385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUA70_RS05390	COG0510	thiamine kinase activity
MUA70_RS05395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MUA70_RS05405	COG1363	Peptidase, m42
MUA70_RS05410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA70_RS05415	COG4848	Belongs to the UPF0354 family
MUA70_RS05420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUA70_RS05425	COG1674	ftsk spoiiie
MUA70_RS05430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MUA70_RS05435	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MUA70_RS05445	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MUA70_RS05445	COG1605	Chorismate mutase
MUA70_RS05450	COG1609	Transcriptional regulator
MUA70_RS05455	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MUA70_RS05470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MUA70_RS05475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUA70_RS05480	COG0204	Acyl-transferase
MUA70_RS05485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MUA70_RS05485	COG1263	PTS System
MUA70_RS05495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MUA70_RS05500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MUA70_RS05505	COG1764	response to oxidative stress
MUA70_RS05510	COG0584	glycerophosphoryl diester phosphodiesterase
MUA70_RS05515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MUA70_RS05520	COG1956	GAF domain-containing protein
MUA70_RS05525	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MUA70_RS05535	COG0301	tRNA thio-modification
MUA70_RS05545	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MUA70_RS05550	COG0827	DNA restriction-modification system
MUA70_RS05555	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MUA70_RS05560	COG0589	response to stress
MUA70_RS05565	COG0686	Belongs to the AlaDH PNT family
MUA70_RS05570	COG0006	proline dipeptidase activity
MUA70_RS05575	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MUA70_RS05585	COG4109	DRTGG domain
MUA70_RS05590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MUA70_RS05595	COG0587	DNA-directed DNA polymerase activity
MUA70_RS05600	COG0281	malic enzyme
MUA70_RS05605	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MUA70_RS05610	COG0825	malonyl-CoA metabolic process
MUA70_RS05615	COG0205	6-phosphofructokinase activity
MUA70_RS05620	COG0469	pyruvate kinase activity
MUA70_RS05625	COG1113	amino acid transport
MUA70_RS05630	COG0372	Belongs to the citrate synthase family
MUA70_RS05635	COG0538	isocitrate dehydrogenase activity
MUA70_RS05640	COG0745	RESPONSE REGULATOR receiver
MUA70_RS05645	COG5002	protein histidine kinase activity
MUA70_RS05650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA70_RS05650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA70_RS05660	COG0237	dephospho-CoA kinase activity
MUA70_RS05670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MUA70_RS05675	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MUA70_RS05680	COG3611	Membrane attachment protein
MUA70_RS05685	COG1484	DNA-dependent DNA replication
MUA70_RS05690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MUA70_RS05695	COG0833	amino acid
MUA70_RS05700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MUA70_RS05705	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MUA70_RS05710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MUA70_RS05715	COG4112	unkown
MUA70_RS05725	COG0544	peptidyl-prolyl cis-trans isomerase activity
MUA70_RS05730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MUA70_RS05735	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MUA70_RS05740	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MUA70_RS05750	COG0181	hydroxymethylbilane synthase activity
MUA70_RS05760	COG0113	porphobilinogen synthase activity
MUA70_RS05765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MUA70_RS05775	COG2818	Glycosylase
MUA70_RS05780	COG0525	valine-tRNA ligase activity
MUA70_RS05785	COG0285	dihydrofolate synthase activity
MUA70_RS05795	COG2003	Belongs to the UPF0758 family
MUA70_RS05825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MUA70_RS05830	COG2868	ribosomal protein
MUA70_RS05835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MUA70_RS05840	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MUA70_RS05845	COG4492	Belongs to the UPF0735 family
MUA70_RS05850	COG0632	four-way junction helicase activity
MUA70_RS05855	COG2255	four-way junction helicase activity
MUA70_RS05860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MUA70_RS05865	COG0343	queuine tRNA-ribosyltransferase activity
MUA70_RS05870	COG1862	Preprotein translocase
MUA70_RS05875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUA70_RS05875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MUA70_RS05880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MUA70_RS05880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MUA70_RS05885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA70_RS05890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MUA70_RS05895	COG1490	D-aminoacyl-tRNA deacylase activity
MUA70_RS05900	COG0860	N-Acetylmuramoyl-L-alanine amidase
MUA70_RS05905	COG0124	histidyl-tRNA synthetase
MUA70_RS05910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MUA70_RS05920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MUA70_RS05925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MUA70_RS05930	COG1959	2 iron, 2 sulfur cluster binding
MUA70_RS05940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUA70_RS05945	COG1104	cysteine desulfurase activity
MUA70_RS05950	COG0482	sulfurtransferase activity
MUA70_RS05965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MUA70_RS05970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MUA70_RS05975	COG4472	Bacterial protein of unknown function (DUF965)
MUA70_RS05980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MUA70_RS05985	COG3906	Belongs to the UPF0473 family
MUA70_RS05995	COG0826	peptidase U32
MUA70_RS06000	COG0826	peptidase U32
MUA70_RS06005	COG0572	uridine kinase
MUA70_RS06010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MUA70_RS06020	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MUA70_RS06025	COG1984	allophanate hydrolase subunit 2
MUA70_RS06030	COG0511	ligase activity, forming carbon-carbon bonds
MUA70_RS06035	COG0439	Biotin carboxylase
MUA70_RS06040	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MUA70_RS06045	COG1914	H( )-stimulated, divalent metal cation uptake system
MUA70_RS06050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MUA70_RS06055	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MUA70_RS06060	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MUA70_RS06065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MUA70_RS06070	COG1534	Rna-binding protein
MUA70_RS06075	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MUA70_RS06080	COG1713	HD superfamily hydrolase involved in NAD metabolism
MUA70_RS06085	COG0799	negative regulation of ribosome biogenesis
MUA70_RS06090	COG2226	methyltransferase
MUA70_RS06100	COG2131	deaminase
MUA70_RS06105	COG0658	competence protein
MUA70_RS06105	COG2333	competence protein COMEC
MUA70_RS06110	COG1466	dna polymerase III delta subunit
MUA70_RS06120	COG0268	Binds directly to 16S ribosomal RNA
MUA70_RS06125	COG0481	GTPase activity
MUA70_RS06130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MUA70_RS06135	COG1420	regulation of RNA biosynthetic process
MUA70_RS06140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MUA70_RS06145	COG0443	Heat shock 70 kDa protein
MUA70_RS06150	COG0484	heat shock protein binding
MUA70_RS06155	COG2264	protein methyltransferase activity
MUA70_RS06160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MUA70_RS06165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUA70_RS06175	COG1030	water channel activity
MUA70_RS06180	COG4864	UPF0365 protein
MUA70_RS06190	COG1702	phosphate starvation-inducible protein PhoH
MUA70_RS06195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MUA70_RS06200	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MUA70_RS06205	COG0295	cytidine deaminase activity
MUA70_RS06210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MUA70_RS06215	COG1381	Involved in DNA repair and RecF pathway recombination
MUA70_RS06220	COG0423	glycine-tRNA ligase activity
MUA70_RS06225	COG0517	IMP dehydrogenase activity
MUA70_RS06230	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MUA70_RS06235	COG0358	DNA primase activity
MUA70_RS06240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MUA70_RS06245	COG2384	SAM-dependent methyltransferase
MUA70_RS06250	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MUA70_RS06255	COG0513	Belongs to the DEAD box helicase family
MUA70_RS06260	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MUA70_RS06265	COG1121	(ABC) transporter
MUA70_RS06270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUA70_RS06275	COG0735	belongs to the Fur family
MUA70_RS06280	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MUA70_RS06285	COG0768	penicillin binding
MUA70_RS06290	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUA70_RS06295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MUA70_RS06300	COG0705	Rhomboid family
MUA70_RS06300	COG0457	Tetratricopeptide repeat
MUA70_RS06305	COG4483	Protein conserved in bacteria
MUA70_RS06310	COG1940	carbohydrate kinase activity
MUA70_RS06315	COG0011	TIGRFAM Protein of
MUA70_RS06320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MUA70_RS06325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MUA70_RS06330	COG1459	type II secretion system
MUA70_RS06335	COG4537	Required for transformation and DNA binding
MUA70_RS06355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MUA70_RS06360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MUA70_RS06365	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUA70_RS06370	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MUA70_RS06380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MUA70_RS06385	COG0095	Lipoate-protein ligase
MUA70_RS06400	COG0006	proline dipeptidase activity
MUA70_RS06410	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MUA70_RS06415	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MUA70_RS06420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MUA70_RS06425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUA70_RS06430	COG0511	ligase activity, forming carbon-carbon bonds
MUA70_RS06435	COG0439	Biotin carboxylase
MUA70_RS06440	COG1302	Protein conserved in bacteria
MUA70_RS06445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUA70_RS06450	COG1570	exodeoxyribonuclease VII activity
MUA70_RS06455	COG1722	exodeoxyribonuclease VII activity
MUA70_RS06465	COG1438	arginine binding
MUA70_RS06470	COG0497	DNA recombination
MUA70_RS06475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUA70_RS06480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MUA70_RS06485	COG0022	dehydrogenase e1 component
MUA70_RS06490	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUA70_RS06500	COG4129	membrane
MUA70_RS06510	COG2195	Cleaves the N-terminal amino acid of tripeptides
MUA70_RS06515	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MUA70_RS06520	COG0366	Alpha amylase catalytic
MUA70_RS06530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MUA70_RS06535	COG1234	tRNA 3'-trailer cleavage
MUA70_RS06540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MUA70_RS06545	COG1028	Short-chain dehydrogenase reductase Sdr
MUA70_RS06550	COG0667	Aldo Keto reductase
MUA70_RS06555	COG0494	nUDIX hydrolase
MUA70_RS06560	COG0735	belongs to the Fur family
MUA70_RS06565	COG4974	Belongs to the 'phage' integrase family
MUA70_RS06570	COG1547	Domain of unknown function (DUF309)
MUA70_RS06575	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MUA70_RS06580	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MUA70_RS06585	COG1187	pseudouridine synthase activity
MUA70_RS06590	COG0745	RESPONSE REGULATOR receiver
MUA70_RS06605	COG1141	Ferredoxin
MUA70_RS06615	COG0514	ATP-dependent DNA helicase (RecQ)
MUA70_RS06620	COG1388	LysM domain
MUA70_RS06625	COG0492	ferredoxin-NADP+ reductase activity
MUA70_RS06630	COG0252	asparaginase activity
MUA70_RS06635	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MUA70_RS06640	COG0539	negative regulation of cytoplasmic translation
MUA70_RS06645	COG1160	GTP binding
MUA70_RS06650	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MUA70_RS06665	COG2226	methyltransferase
MUA70_RS06675	COG0105	UTP biosynthetic process
MUA70_RS06680	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MUA70_RS06685	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MUA70_RS06690	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MUA70_RS06700	COG5582	Belongs to the UPF0302 family
MUA70_RS06705	COG4347	Protein of unknown function (DUF1405)
MUA70_RS06710	COG2738	Putative neutral zinc metallopeptidase
MUA70_RS06715	COG1694	Mazg nucleotide pyrophosphohydrolase
MUA70_RS06720	COG0438	transferase activity, transferring glycosyl groups
MUA70_RS06725	COG0617	tRNA 3'-terminal CCA addition
MUA70_RS06730	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MUA70_RS06730	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MUA70_RS06735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MUA70_RS06735	COG1199	ATP-dependent helicase activity
MUA70_RS06740	COG0017	Asparaginyl-tRNA synthetase
MUA70_RS06745	COG3935	DnaD domain protein
MUA70_RS06750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MUA70_RS06760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MUA70_RS06760	COG4499	WXG100 protein secretion system (Wss), protein YukC
MUA70_RS06765	COG3331	DNA recombination
MUA70_RS06775	COG4474	Belongs to the UPF0398 family
MUA70_RS06780	COG3599	regulation of cell shape
MUA70_RS06790	COG0116	Belongs to the methyltransferase superfamily
MUA70_RS06800	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MUA70_RS06805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MUA70_RS06810	COG1196	nuclear chromosome segregation
MUA70_RS06810	COG1511	domain protein
MUA70_RS06810	COG4372	Transposase
MUA70_RS06820	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MUA70_RS06830	COG1413	lyase activity
MUA70_RS06845	COG1136	(ABC) transporter
MUA70_RS06870	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MUA70_RS06875	COG2190	(PTS) system
MUA70_RS06880	COG4479	Belongs to the UPF0346 family
MUA70_RS06885	COG0793	Belongs to the peptidase S41A family
MUA70_RS06895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUA70_RS06900	COG0671	phosphoesterase, PA-phosphatase related
MUA70_RS06905	COG3842	ATPase activity
MUA70_RS06910	COG4209	transmembrane transport
MUA70_RS06920	COG0395	ABC-type sugar transport system, permease component
MUA70_RS06930	COG0534	Mate efflux family protein
MUA70_RS06935	COG1349	DNA-binding transcription factor activity
MUA70_RS06940	COG0745	RESPONSE REGULATOR receiver
MUA70_RS06945	COG5002	protein histidine kinase activity
MUA70_RS06950	COG0567	Dehydrogenase, E1 component
MUA70_RS06955	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUA70_RS06960	COG1131	(ABC) transporter
MUA70_RS06980	COG0714	Associated with various cellular activities
MUA70_RS06985	COG4548	von Willebrand factor, type A
MUA70_RS06990	COG1114	Component of the transport system for branched-chain amino acids
MUA70_RS06995	COG3853	Toxic anion resistance protein (TelA)
MUA70_RS07005	COG1254	Belongs to the acylphosphatase family
MUA70_RS07015	COG1278	Cold shock
MUA70_RS07035	COG1473	amidohydrolase
MUA70_RS07040	COG2171	N-acyltransferase activity
MUA70_RS07045	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MUA70_RS07050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MUA70_RS07055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MUA70_RS07060	COG0527	aspartate kinase activity
MUA70_RS07065	COG0488	(ABC) transporter
MUA70_RS07070	COG2996	Protein conserved in bacteria
MUA70_RS07075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MUA70_RS07080	COG0573	inorganic phosphate transmembrane transporter activity
MUA70_RS07085	COG0581	inorganic phosphate transmembrane transporter activity
MUA70_RS07090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MUA70_RS07095	COG0704	Plays a role in the regulation of phosphate uptake
MUA70_RS07100	COG1164	Oligoendopeptidase f
MUA70_RS07130	COG4607	ABC-type enterochelin transport system periplasmic component
MUA70_RS07140	COG2348	transferase activity, transferring amino-acyl groups
MUA70_RS07145	COG2348	transferase activity, transferring amino-acyl groups
MUA70_RS07155	COG0159	tryptophan synthase activity
MUA70_RS07160	COG0133	tryptophan synthase activity
MUA70_RS07165	COG0135	phosphoribosylanthranilate isomerase activity
MUA70_RS07170	COG0134	indole-3-glycerol-phosphate synthase activity
MUA70_RS07175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MUA70_RS07180	COG0512	Glutamine amidotransferase of anthranilate synthase
MUA70_RS07180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MUA70_RS07185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MUA70_RS07190	COG0287	Prephenate dehydrogenase
MUA70_RS07195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MUA70_RS07200	COG1942	4-Oxalocrotonate Tautomerase
MUA70_RS07215	COG0392	lysyltransferase activity
MUA70_RS07215	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MUA70_RS07220	COG0628	permease
MUA70_RS07225	COG3711	transcriptional antiterminator
MUA70_RS07230	COG1115	amino acid carrier protein
MUA70_RS07235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MUA70_RS07240	COG0187	DNA topoisomerase II activity
MUA70_RS07245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MUA70_RS07250	COG4841	protein insertion into membrane
MUA70_RS07255	COG0824	Thioesterase
MUA70_RS07260	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MUA70_RS07265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MUA70_RS07270	COG1970	mechanosensitive ion channel activity
MUA70_RS07275	COG0419	ATPase involved in DNA repair
MUA70_RS07280	COG0420	3'-5' exonuclease activity
MUA70_RS07285	COG4846	Membrane protein involved in cytochrome C biogenesis
MUA70_RS07295	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MUA70_RS07300	COG4224	UPF0291 protein
MUA70_RS07310	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MUA70_RS07320	COG0516	GMP reductase activity
MUA70_RS07325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MUA70_RS07340	COG0833	amino acid
MUA70_RS07355	COG0083	homoserine kinase activity
MUA70_RS07360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MUA70_RS07365	COG0460	homoserine dehydrogenase
MUA70_RS07370	COG0527	aspartate kinase activity
MUA70_RS07395	COG1525	nuclease
MUA70_RS07405	COG2197	response regulator
MUA70_RS07410	COG4585	Histidine kinase
MUA70_RS07420	COG1131	(ABC) transporter
MUA70_RS07430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MUA70_RS07485	COG4824	toxin secretion phage lysis holin
MUA70_RS07590	COG1783	phage Terminase large subunit
MUA70_RS07680	COG0174	glutamine synthetase
MUA70_RS07685	COG0789	Transcriptional regulator
MUA70_RS07690	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MUA70_RS07695	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MUA70_RS07700	COG0386	Belongs to the glutathione peroxidase family
MUA70_RS07705	COG1923	regulation of RNA biosynthetic process
MUA70_RS07710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MUA70_RS07720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MUA70_RS07725	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MUA70_RS07730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MUA70_RS07735	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MUA70_RS07740	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MUA70_RS07745	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MUA70_RS07755	COG4550	Control of competence regulator ComK, YlbF/YmcA
MUA70_RS07760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MUA70_RS07770	COG4195	phage-related replication protein
MUA70_RS07775	COG1013	pyruvate-flavodoxin oxidoreductase activity
MUA70_RS07780	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MUA70_RS07780	COG0674	pyruvate-flavodoxin oxidoreductase activity
MUA70_RS07785	COG1692	metallophosphoesterase
MUA70_RS07800	COG1418	mRNA catabolic process
MUA70_RS07805	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MUA70_RS07810	COG1546	Belongs to the CinA family
MUA70_RS07810	COG1058	Belongs to the CinA family
MUA70_RS07815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MUA70_RS07830	COG0300	oxidoreductase activity
MUA70_RS07835	COG0612	Peptidase, M16
MUA70_RS07840	COG0612	Peptidase, M16
MUA70_RS07845	COG2188	Transcriptional regulator
MUA70_RS07850	COG1674	ftsk spoiiie
MUA70_RS07855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MUA70_RS07860	COG1185	polyribonucleotide nucleotidyltransferase activity
MUA70_RS07865	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MUA70_RS07870	COG0196	riboflavin kinase activity
MUA70_RS07875	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MUA70_RS07880	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MUA70_RS07885	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MUA70_RS07890	COG1358	cellular component organization or biogenesis
MUA70_RS07895	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MUA70_RS07900	COG0195	Participates in both transcription termination and antitermination
MUA70_RS07905	COG0779	Required for maturation of 30S ribosomal subunits
MUA70_RS07910	COG2176	DNA-directed DNA polymerase activity
MUA70_RS07915	COG0442	prolyl-tRNA aminoacylation
MUA70_RS07925	COG4589	Belongs to the CDS family
MUA70_RS07930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MUA70_RS07935	COG0233	cytoplasmic translational termination
MUA70_RS07940	COG0528	UMP kinase activity
MUA70_RS07945	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MUA70_RS07950	COG0052	Belongs to the universal ribosomal protein uS2 family
MUA70_RS07955	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MUA70_RS07960	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MUA70_RS07965	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MUA70_RS07970	COG4974	Belongs to the 'phage' integrase family
MUA70_RS07975	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MUA70_RS07980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MUA70_RS07985	COG0758	DNA mediated transformation
MUA70_RS07995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MUA70_RS08000	COG0045	succinate-CoA ligase (ADP-forming) activity
MUA70_RS08005	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUA70_RS08015	COG4485	Bacterial membrane protein, YfhO
MUA70_RS08025	COG0335	large ribosomal subunit rRNA binding
MUA70_RS08030	COG0336	Belongs to the RNA methyltransferase TrmD family
MUA70_RS08035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MUA70_RS08040	COG0228	four-way junction DNA binding
MUA70_RS08045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MUA70_RS08050	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MUA70_RS08055	COG0552	protein localization to endoplasmic reticulum
MUA70_RS08060	COG1196	nuclear chromosome segregation
MUA70_RS08065	COG0571	ribonuclease III activity
MUA70_RS08070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUA70_RS08075	COG1028	Short-chain dehydrogenase reductase Sdr
MUA70_RS08085	COG0416	fatty acid biosynthetic process
MUA70_RS08090	COG1349	DNA-binding transcription factor activity
MUA70_RS08095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MUA70_RS08100	COG1461	Dihydroxyacetone kinase
MUA70_RS08105	COG1302	Protein conserved in bacteria
MUA70_RS08110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MUA70_RS08120	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MUA70_RS08125	COG1162	GTPase activity
MUA70_RS08135	COG0631	protein serine/threonine phosphatase activity
MUA70_RS08140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MUA70_RS08145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MUA70_RS08145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MUA70_RS08150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MUA70_RS08155	COG0242	peptide deformylase activity
MUA70_RS08165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MUA70_RS08170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MUA70_RS08175	COG1758	RNA polymerase activity
MUA70_RS08180	COG0194	GDP metabolic process
MUA70_RS08200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MUA70_RS08205	COG0284	orotidine-5'-phosphate decarboxylase activity
MUA70_RS08210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MUA70_RS08215	COG0505	Belongs to the CarA family
MUA70_RS08220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MUA70_RS08225	COG0540	Belongs to the ATCase OTCase family
MUA70_RS08230	COG2233	PERMEase
MUA70_RS08235	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MUA70_RS08240	COG0564	pseudouridine synthase activity
MUA70_RS08245	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MUA70_RS08250	COG3942	CHAP domain
MUA70_RS08250	COG1388	LysM domain
MUA70_RS08260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MUA70_RS08265	COG3599	regulation of cell shape
MUA70_RS08275	COG0762	integral membrane protein
MUA70_RS08280	COG1799	cell septum assembly
MUA70_RS08285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MUA70_RS08290	COG1496	oxidoreductase activity
MUA70_RS08295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MUA70_RS08300	COG0849	cell division
MUA70_RS08305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MUA70_RS08310	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MUA70_RS08315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUA70_RS08320	COG0768	penicillin binding
MUA70_RS08325	COG4839	cell division protein FtsL
MUA70_RS08330	COG0275	rRNA processing
MUA70_RS08335	COG2001	Belongs to the MraZ family
MUA70_RS08340	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MUA70_RS08345	COG0454	-acetyltransferase
MUA70_RS08350	COG1011	Hydrolase
MUA70_RS08390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MUA70_RS08395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MUA70_RS08400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MUA70_RS08405	COG1053	succinate dehydrogenase
MUA70_RS08410	COG2009	succinate dehydrogenase
MUA70_RS08420	COG0322	excinuclease ABC activity
MUA70_RS08425	COG3118	belongs to the thioredoxin family
MUA70_RS08430	COG1193	negative regulation of DNA recombination
MUA70_RS08435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MUA70_RS08435	COG1796	DNA polymerase
MUA70_RS08445	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MUA70_RS08450	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MUA70_RS08455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUA70_RS08455	COG0072	phenylalanine-tRNA ligase activity
MUA70_RS08460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MUA70_RS08465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUA70_RS08475	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MUA70_RS08485	COG1323	Belongs to the UPF0348 family
MUA70_RS08490	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MUA70_RS08495	COG0742	ribosomal rna small subunit methyltransferase
MUA70_RS08505	COG4471	UPF0298 protein
MUA70_RS08510	COG0584	glycerophosphoryl diester phosphodiesterase
MUA70_RS08515	COG3679	Belongs to the UPF0342 family
MUA70_RS08520	COG2340	Cysteine-rich secretory protein family
MUA70_RS08530	COG0109	protoheme IX farnesyltransferase activity
MUA70_RS08535	COG1612	heme a metabolic process
MUA70_RS08545	COG0772	Belongs to the SEDS family
MUA70_RS08550	COG4838	Belongs to the UPF0358 family
MUA70_RS08555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MUA70_RS08560	COG4896	Protein conserved in bacteria
MUA70_RS08565	COG1217	gtp-binding protein TYPA
MUA70_RS08575	COG0483	inositol monophosphate 1-phosphatase activity
MUA70_RS08580	COG4493	Belongs to the UPF0637 family
MUA70_RS08585	COG1914	H( )-stimulated, divalent metal cation uptake system
MUA70_RS08610	COG1176	ABC-type spermidine putrescine transport system, permease component I
MUA70_RS08615	COG3842	ATPase activity
MUA70_RS08625	COG4476	Belongs to the UPF0223 family
MUA70_RS08635	COG0508	dehydrogenase complex catalyzes the overall conversion of
MUA70_RS08640	COG0022	dehydrogenase e1 component
MUA70_RS08645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MUA70_RS08655	COG0242	peptide deformylase activity
MUA70_RS08660	COG5503	Protein of unknown function (DUF1447)
MUA70_RS08665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MUA70_RS08670	COG0569	domain protein
MUA70_RS08675	COG1294	oxidase, subunit
MUA70_RS08680	COG1271	oxidase subunit
MUA70_RS08690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MUA70_RS08695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA70_RS08705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MUA70_RS08720	COG4716	Myosin-crossreactive antigen
MUA70_RS08730	COG4172	Belongs to the ABC transporter superfamily
MUA70_RS08735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MUA70_RS08740	COG0151	Belongs to the GarS family
MUA70_RS08745	COG0138	bifunctional purine biosynthesis protein purh
MUA70_RS08750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MUA70_RS08755	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MUA70_RS08760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MUA70_RS08765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUA70_RS08770	COG0047	phosphoribosylformylglycinamidine synthase activity
MUA70_RS08775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MUA70_RS08780	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MUA70_RS08785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MUA70_RS08790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MUA70_RS08795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MUA70_RS08805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MUA70_RS08810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MUA70_RS08815	COG1845	cytochrome c oxidase, subunit III
MUA70_RS08820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MUA70_RS08835	COG1316	TRANSCRIPTIONal
MUA70_RS08860	COG3594	Acyltransferase
MUA70_RS08865	COG0436	Aminotransferase
MUA70_RS08870	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MUA70_RS08880	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MUA70_RS08885	COG1169	isochorismate synthase
MUA70_RS08890	COG1575	Belongs to the MenA family. Type 1 subfamily
MUA70_RS08895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MUA70_RS08900	COG2314	TM2 domain
MUA70_RS08940	COG4873	Protein conserved in bacteria
MUA70_RS08950	COG0737	Belongs to the 5'-nucleotidase family
MUA70_RS08955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUA70_RS08960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MUA70_RS08965	COG0861	Integral membrane protein TerC family
MUA70_RS08970	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MUA70_RS08980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MUA70_RS08985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MUA70_RS08990	COG2814	Major facilitator Superfamily
MUA70_RS08995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MUA70_RS09000	COG2382	esterase
MUA70_RS09005	COG0628	permease
MUA70_RS09050	COG1733	regulation of RNA biosynthetic process
MUA70_RS09075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MUA70_RS09165	COG0475	glutathione-regulated potassium exporter activity
MUA70_RS09165	COG0569	domain protein
MUA70_RS09170	COG2239	Acts as a magnesium transporter
MUA70_RS09175	COG0564	pseudouridine synthase activity
MUA70_RS09180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MUA70_RS09185	COG2357	RelA SpoT domain protein
MUA70_RS09200	COG2346	COG2346, Truncated hemoglobins
MUA70_RS09205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MUA70_RS09210	COG1164	Oligoendopeptidase f
MUA70_RS09220	COG4862	establishment of competence for transformation
MUA70_RS09225	COG1393	Belongs to the ArsC family
MUA70_RS09230	COG0180	Tryptophanyl-tRNA synthetase
MUA70_RS09245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MUA70_RS09265	COG0542	response to heat
MUA70_RS09280	COG0561	phosphatase activity
MUA70_RS09285	COG0446	pyridine nucleotide-disulphide oxidoreductase
MUA70_RS09295	COG0179	Fumarylacetoacetate (FAA) hydrolase
MUA70_RS09300	COG1074	ATP-dependent DNA helicase activity
MUA70_RS09305	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MUA70_RS09320	COG0398	Pfam SNARE associated Golgi protein
MUA70_RS09335	COG0166	Belongs to the GPI family
MUA70_RS09340	COG0137	argininosuccinate synthase activity
MUA70_RS09345	COG0165	Argininosuccinate lyase
MUA70_RS09350	COG0584	glycerophosphoryl diester phosphodiesterase
MUA70_RS09360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MUA70_RS09365	COG1902	pentaerythritol trinitrate reductase activity
MUA70_RS09370	COG1098	S1 RNA binding domain
MUA70_RS09375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MUA70_RS09385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUA70_RS09385	COG2111	Na H antiporter
MUA70_RS09390	COG2111	Na H antiporter
MUA70_RS09395	COG1006	Multisubunit Na H antiporter MnhC subunit
MUA70_RS09400	COG0651	ATP synthesis coupled electron transport
MUA70_RS09405	COG1863	multisubunit Na H antiporter MnhE subunit
MUA70_RS09410	COG2212	antiporter activity
MUA70_RS09415	COG1320	monovalent cation:proton antiporter activity
MUA70_RS09425	COG2050	protein possibly involved in aromatic compounds catabolism
MUA70_RS09430	COG2056	Na+-H+ antiporter family
MUA70_RS09435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MUA70_RS09440	COG1252	NADH dehydrogenase
MUA70_RS09445	COG0316	Belongs to the HesB IscA family
MUA70_RS09450	COG4844	belongs to the
MUA70_RS09455	COG1252	NADH dehydrogenase
MUA70_RS09460	COG4837	Protein of unknown function (DUF1462)
MUA70_RS09465	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MUA70_RS09470	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MUA70_RS09475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MUA70_RS09480	COG1696	Membrane protein involved in D-alanine export
MUA70_RS09485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MUA70_RS09500	COG0647	UMP catabolic process
MUA70_RS09505	COG2445	Protein of unknown function DUF86
MUA70_RS09520	COG4470	Protein conserved in bacteria
MUA70_RS09525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MUA70_RS09530	COG0737	Belongs to the 5'-nucleotidase family
MUA70_RS09535	COG0730	response to heat
MUA70_RS09540	COG1801	Protein of unknown function DUF72
MUA70_RS09545	COG1253	flavin adenine dinucleotide binding
MUA70_RS09560	COG0719	Fe-S assembly protein
MUA70_RS09565	COG0822	iron-sulfur transferase activity
MUA70_RS09570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MUA70_RS09575	COG0719	Fe-S assembly protein
MUA70_RS09580	COG0396	ATPase activity
MUA70_RS09590	COG3237	CsbD-like
MUA70_RS09595	COG1464	Belongs to the NlpA lipoprotein family
MUA70_RS09600	COG2011	ABC-type metal ion transport system permease component
MUA70_RS09605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MUA70_RS09615	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MUA70_RS09620	COG0509	glycine decarboxylation via glycine cleavage system
MUA70_RS09625	COG1393	Belongs to the ArsC family
MUA70_RS09630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MUA70_RS09640	COG0710	3-dehydroquinate dehydratase activity
MUA70_RS09645	COG1764	response to oxidative stress
MUA70_RS09690	COG4195	phage-related replication protein
MUA70_RS09705	COG1278	Cold shock
MUA70_RS09730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MUA70_RS09770	COG0110	maltose O-acetyltransferase activity
MUA70_RS09835	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MUA70_RS09840	COG0557	exoribonuclease II activity
MUA70_RS09845	COG1647	Serine aminopeptidase, S33
MUA70_RS09850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MUA70_RS09860	COG0148	phosphopyruvate hydratase activity
MUA70_RS09865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MUA70_RS09870	COG0149	triose-phosphate isomerase activity
MUA70_RS09875	COG0126	phosphoglycerate kinase activity
MUA70_RS09880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MUA70_RS09900	COG1090	epimerase
MUA70_RS09910	COG0740	serine-type endopeptidase activity
MUA70_RS09920	COG1481	regulation of sporulation
MUA70_RS09925	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MUA70_RS09930	COG1660	Displays ATPase and GTPase activities
MUA70_RS09935	COG0492	ferredoxin-NADP+ reductase activity
MUA70_RS09950	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MUA70_RS09955	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MUA70_RS09960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MUA70_RS09965	COG0556	nucleotide-excision repair
MUA70_RS09980	COG3942	CHAP domain
MUA70_RS09980	COG1388	LysM domain
MUA70_RS09990	COG0653	protein targeting
MUA70_RS09995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MUA70_RS10000	COG1040	competence protein
MUA70_RS10005	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MUA70_RS10015	COG1739	Uncharacterized protein family UPF0029
MUA70_RS10020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MUA70_RS10025	COG2199	diguanylate cyclase activity
MUA70_RS10040	COG2195	Cleaves the N-terminal amino acid of tripeptides
MUA70_RS10045	COG1929	Belongs to the glycerate kinase type-1 family
MUA70_RS10065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MUA70_RS10080	COG4604	ABC transporter, ATP-binding protein
MUA70_RS10085	COG4605	iron ion homeostasis
MUA70_RS10090	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA70_RS10100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUA70_RS10105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MUA70_RS10110	COG1780	Probably involved in ribonucleotide reductase function
MUA70_RS10120	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MUA70_RS10125	COG3104	oligopeptide transport
MUA70_RS10130	COG1597	lipid kinase activity
MUA70_RS10135	COG1012	belongs to the aldehyde dehydrogenase family
MUA70_RS10135	COG1454	alcohol dehydrogenase
MUA70_RS10140	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MUA70_RS10145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MUA70_RS10150	COG1174	glycine betaine transport
MUA70_RS10155	COG1125	glycine betaine transport
MUA70_RS10155	COG0517	IMP dehydrogenase activity
MUA70_RS10160	COG0514	ATP-dependent DNA helicase (RecQ)
MUA70_RS10165	COG0488	(ABC) transporter
MUA70_RS10180	COG1368	sulfuric ester hydrolase activity
MUA70_RS10190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MUA70_RS10205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MUA70_RS10215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MUA70_RS10220	COG0720	synthase
MUA70_RS10225	COG0602	queuosine metabolic process
MUA70_RS10250	COG0745	RESPONSE REGULATOR receiver
MUA70_RS10255	COG5002	protein histidine kinase activity
MUA70_RS10260	COG0463	Glycosyl transferase, family 2
MUA70_RS10265	COG0656	L-ascorbic acid biosynthetic process
MUA70_RS10270	COG1253	flavin adenine dinucleotide binding
MUA70_RS10275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MUA70_RS10290	COG1733	regulation of RNA biosynthetic process
MUA70_RS10310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA70_RS10310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MUA70_RS10310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MUA70_RS10315	COG1105	Belongs to the carbohydrate kinase PfkB family
MUA70_RS10320	COG1349	DNA-binding transcription factor activity
MUA70_RS10325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MUA70_RS10350	COG0415	Belongs to the DNA photolyase family
MUA70_RS10360	COG0471	metal ion transport
MUA70_RS10365	COG0039	L-malate dehydrogenase activity
MUA70_RS10385	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MUA70_RS10390	COG4988	ABC transporter
MUA70_RS10395	COG1968	undecaprenyl-diphosphatase activity
MUA70_RS10410	COG1671	Belongs to the UPF0178 family
MUA70_RS10415	COG1611	Belongs to the LOG family
MUA70_RS10440	COG2839	Protein conserved in bacteria
MUA70_RS10445	COG2814	Major facilitator Superfamily
MUA70_RS10450	COG0583	DNA-binding transcription factor activity
MUA70_RS10470	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MUA70_RS10480	COG0217	transcriptional regulatory protein
MUA70_RS10500	COG3942	CHAP domain
MUA70_RS10500	COG1388	LysM domain
MUA70_RS10505	COG0306	phosphate transporter
MUA70_RS10510	COG1392	Phosphate transport regulator
MUA70_RS10515	COG0577	efflux transmembrane transporter activity
MUA70_RS10520	COG1136	(ABC) transporter
MUA70_RS10525	COG2205	protein histidine kinase activity
MUA70_RS10530	COG0745	RESPONSE REGULATOR receiver
MUA70_RS10535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUA70_RS10550	COG3949	Membrane
MUA70_RS10560	COG1120	ATPase activity
MUA70_RS10565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MUA70_RS10570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUA70_RS10575	COG1132	(ABC) transporter
MUA70_RS10580	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MUA70_RS10590	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA70_RS10595	COG1682	transport, permease protein
MUA70_RS10600	COG1134	teichoic acid transport
MUA70_RS10605	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MUA70_RS10615	COG1321	iron dependent repressor
MUA70_RS10620	COG1121	(ABC) transporter
MUA70_RS10625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MUA70_RS10630	COG0803	Belongs to the bacterial solute-binding protein 9 family
MUA70_RS10640	COG1320	monovalent cation:proton antiporter activity
MUA70_RS10645	COG2212	antiporter activity
MUA70_RS10650	COG1863	multisubunit Na H antiporter MnhE subunit
MUA70_RS10655	COG0651	ATP synthesis coupled electron transport
MUA70_RS10660	COG1006	Multisubunit Na H antiporter MnhC subunit
MUA70_RS10665	COG2111	Na H antiporter
MUA70_RS10670	COG2111	Na H antiporter
MUA70_RS10670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUA70_RS10700	COG0596	Alpha beta hydrolase
MUA70_RS10720	COG0546	phosphoglycolate phosphatase activity
MUA70_RS10725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MUA70_RS10730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MUA70_RS10740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MUA70_RS10745	COG0018	arginyl-trna synthetase
MUA70_RS10760	COG1064	alcohol dehydrogenase
MUA70_RS10765	COG3875	lactate racemase activity
MUA70_RS10770	COG1606	tRNA processing
MUA70_RS10775	COG1691	(AIR) carboxylase
MUA70_RS10780	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MUA70_RS10790	COG1078	dGTPase activity
MUA70_RS10810	COG2113	Glycine betaine
MUA70_RS10815	COG2409	Drug exporters of the RND superfamily
MUA70_RS10820	COG0667	Aldo Keto reductase
MUA70_RS10830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MUA70_RS10835	COG4844	belongs to the
MUA70_RS10850	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MUA70_RS10855	COG0095	Lipoate-protein ligase
MUA70_RS10860	COG0280	phosphate acetyltransferase
MUA70_RS10865	COG3253	May function as heme-dependent peroxidase
MUA70_RS10880	COG0531	amino acid
MUA70_RS10885	COG2363	Small membrane protein
MUA70_RS10895	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MUA70_RS10905	COG0351	phosphomethylpyrimidine kinase
MUA70_RS10930	COG0183	Belongs to the thiolase family
MUA70_RS10935	COG0318	PFAM AMP-dependent synthetase and ligase
MUA70_RS10945	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MUA70_RS10950	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MUA70_RS10955	COG0363	glucosamine-6-phosphate deaminase activity
MUA70_RS10965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MUA70_RS10970	COG1469	GTP cyclohydrolase I activity
MUA70_RS10980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MUA70_RS10985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MUA70_RS11000	COG0431	NADPH-dependent FMN reductase
MUA70_RS11005	COG0561	phosphatase activity
MUA70_RS11015	COG1428	Deoxynucleoside kinase
MUA70_RS11020	COG1428	Deoxynucleoside kinase
MUA70_RS11025	COG1028	Short-chain dehydrogenase reductase Sdr
MUA70_RS11030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MUA70_RS11035	COG0546	phosphoglycolate phosphatase activity
MUA70_RS11040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MUA70_RS11045	COG1063	alcohol dehydrogenase
MUA70_RS11050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MUA70_RS11055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MUA70_RS11060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MUA70_RS11080	COG1473	amidohydrolase
MUA70_RS11085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MUA70_RS11090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MUA70_RS11100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MUA70_RS11110	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MUA70_RS11115	COG0085	RNA polymerase activity
MUA70_RS11120	COG2813	Specifically methylates the guanine in position
MUA70_RS11125	COG0222	ribosome binding
MUA70_RS11130	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MUA70_RS11135	COG0081	regulation of translation
MUA70_RS11140	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MUA70_RS11145	COG0250	Participates in transcription elongation, termination and antitermination
MUA70_RS11150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MUA70_RS11155	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MUA70_RS11165	COG3688	RNA-binding protein containing a PIN domain
MUA70_RS11170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MUA70_RS11175	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MUA70_RS11180	COG0215	cysteine-tRNA ligase activity
MUA70_RS11185	COG1045	serine acetyltransferase
MUA70_RS11190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MUA70_RS11195	COG4956	integral membrane protein (PIN domain superfamily)
MUA70_RS11200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MUA70_RS11205	COG0542	response to heat
MUA70_RS11210	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MUA70_RS11215	COG3880	PFAM UvrB UvrC protein
MUA70_RS11220	COG4463	regulation of RNA biosynthetic process
MUA70_RS11225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MUA70_RS11230	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MUA70_RS11235	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MUA70_RS11240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MUA70_RS11330	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MUA70_RS11335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MUA70_RS11340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MUA70_RS11345	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MUA70_RS11350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MUA70_RS11355	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MUA70_RS11360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MUA70_RS11365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MUA70_RS11370	COG0037	tRNA processing
MUA70_RS11375	COG1098	S1 RNA binding domain
MUA70_RS11385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MUA70_RS11390	COG3956	TIGRFAM MazG family protein
MUA70_RS11395	COG2244	polysaccharide biosynthetic process
MUA70_RS11400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MUA70_RS11405	COG0193	aminoacyl-tRNA hydrolase activity
MUA70_RS11410	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MUA70_RS11415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MUA70_RS11420	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MUA70_RS11425	COG2088	sporulation resulting in formation of a cellular spore
MUA70_RS11430	COG0251	oxidation-reduction process
MUA70_RS11435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA70_RS11440	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MUA70_RS11445	COG4466	Protein conserved in bacteria
MUA70_RS11450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MUA70_RS11455	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MUA70_RS11460	COG0084	hydrolase, TatD family'
MUA70_RS11465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUA70_RS11465	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MUA70_RS11470	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MUA70_RS11475	COG2827	Endonuclease containing a URI domain
MUA70_RS11480	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MUA70_RS11485	COG4467	Involved in initiation control of chromosome replication
MUA70_RS11490	COG1774	PSP1 C-terminal conserved region
MUA70_RS11495	COG0470	DNA polymerase III
MUA70_RS11500	COG3870	Protein conserved in bacteria
MUA70_RS11505	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MUA70_RS11510	COG1982	Orn Lys Arg decarboxylase major
MUA70_RS11535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MUA70_RS11540	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MUA70_RS11545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MUA70_RS11570	COG0493	'glutamate synthase
MUA70_RS11575	COG0069	glutamate synthase activity
MUA70_RS11575	COG0067	glutamate synthase
MUA70_RS11575	COG0070	glutamate synthase
MUA70_RS11580	COG0583	DNA-binding transcription factor activity
MUA70_RS11605	COG0438	transferase activity, transferring glycosyl groups
MUA70_RS11610	COG3942	CHAP domain
MUA70_RS11610	COG1388	LysM domain
MUA70_RS11620	COG2011	ABC-type metal ion transport system permease component
MUA70_RS11625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MUA70_RS11630	COG0626	cystathionine gamma-synthase activity
MUA70_RS11635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MUA70_RS11645	COG0733	neurotransmitter:sodium symporter activity
MUA70_RS11655	COG1647	Serine aminopeptidase, S33
MUA70_RS11670	COG5609	conserved protein (DUF2294)
MUA70_RS11675	COG3002	Belongs to the UPF0753 family
MUA70_RS11680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MUA70_RS11695	COG0523	cobalamin synthesis protein
MUA70_RS11715	COG0655	NAD(P)H dehydrogenase (quinone) activity
MUA70_RS11770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MUA70_RS11770	COG0519	Catalyzes the synthesis of GMP from XMP
MUA70_RS11775	COG0516	GMP reductase activity
MUA70_RS11775	COG0517	IMP dehydrogenase activity
MUA70_RS11780	COG2233	PERMEase
MUA70_RS11785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MUA70_RS11800	COG5183	chlorophyll binding
MUA70_RS11805	COG1823	symporter activity
MUA70_RS11810	COG0778	Nitroreductase
MUA70_RS11820	COG0450	alkyl hydroperoxide reductase
MUA70_RS11825	COG3634	alkyl hydroperoxide reductase activity
MUA70_RS11845	COG1280	lysine exporter protein (LysE YggA)
MUA70_RS11865	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MUA70_RS11875	COG0360	Binds together with S18 to 16S ribosomal RNA
MUA70_RS11890	COG0012	GTP binding
MUA70_RS11895	COG4481	Protein conserved in bacteria
MUA70_RS11900	COG0668	transmembrane transport
MUA70_RS11905	COG1475	DNA binding
MUA70_RS11910	COG0626	cystathionine gamma-synthase activity
MUA70_RS11915	COG0626	cystathionine gamma-synthase activity
MUA70_RS11920	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MUA70_RS11920	COG0646	methionine synthase
MUA70_RS11925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MUA70_RS11935	COG0183	Belongs to the thiolase family
MUA70_RS11950	COG1476	TRANSCRIPTIONal
MUA70_RS11960	COG4555	ABC transporter
MUA70_RS12005	COG1136	(ABC) transporter
MUA70_RS12010	COG0577	efflux transmembrane transporter activity
MUA70_RS12025	COG0577	efflux transmembrane transporter activity
MUA70_RS12030	COG1136	(ABC) transporter
MUA70_RS12065	COG1475	DNA binding
MUA70_RS12070	COG0357	Ribosomal RNA small subunit methyltransferase G
MUA70_RS12075	COG0445	tRNA wobble uridine modification
MUA70_RS12080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MUA70_RS12085	COG0594	ribonuclease P activity
MUA70_RS12100	COG3682	Transcriptional regulator
MUA70_RS12115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284