locus-tag	class	description
FNL83_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNL83_RS00010	COG0592	DNA-directed DNA polymerase activity
FNL83_RS00015	COG2501	S4 domain
FNL83_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNL83_RS00025	COG0187	DNA topoisomerase II activity
FNL83_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNL83_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FNL83_RS00040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FNL83_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNL83_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FNL83_RS00075	COG0359	binds to the 23S rRNA
FNL83_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
FNL83_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNL83_RS00105	COG0745	RESPONSE REGULATOR receiver
FNL83_RS00110	COG5002	protein histidine kinase activity
FNL83_RS00115	COG4863	YycH protein
FNL83_RS00125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNL83_RS00130	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FNL83_RS00135	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FNL83_RS00150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNL83_RS00185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FNL83_RS00210	COG0640	Transcriptional regulator
FNL83_RS00220	COG2217	Heavy metal translocating P-type atpase
FNL83_RS00250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FNL83_RS00315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNL83_RS00320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNL83_RS00360	COG2801	Transposase and inactivated derivatives
FNL83_RS00365	COG0549	Belongs to the carbamate kinase family
FNL83_RS00370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNL83_RS00375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNL83_RS00385	COG2235	arginine
FNL83_RS00390	COG1438	arginine binding
FNL83_RS00435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FNL83_RS00445	COG1131	(ABC) transporter
FNL83_RS00460	COG0745	RESPONSE REGULATOR receiver
FNL83_RS00465	COG5002	protein histidine kinase activity
FNL83_RS00490	COG2217	Heavy metal translocating P-type atpase
FNL83_RS00495	COG2132	Multicopper oxidase
FNL83_RS00500	COG1388	LysM domain
FNL83_RS00505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNL83_RS00510	COG2210	Belongs to the sulfur carrier protein TusA family
FNL83_RS00515	COG1937	Protein conserved in bacteria
FNL83_RS00520	COG0730	response to heat
FNL83_RS00525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNL83_RS00530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FNL83_RS00550	COG0640	Transcriptional regulator
FNL83_RS00555	COG0701	Predicted permease
FNL83_RS00580	COG0668	transmembrane transport
FNL83_RS00585	COG0561	phosphatase activity
FNL83_RS00625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNL83_RS00630	COG0579	oxidoreductase
FNL83_RS00645	COG1028	Short-chain dehydrogenase reductase Sdr
FNL83_RS00655	COG1755	Isoprenylcysteine carboxyl methyltransferase
FNL83_RS00665	COG4753	response regulator
FNL83_RS00665	COG2207	Transcriptional regulator
FNL83_RS00670	COG2972	Histidine kinase
FNL83_RS00740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNL83_RS00745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNL83_RS00750	COG0156	8-amino-7-oxononanoate synthase activity
FNL83_RS00755	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
FNL83_RS00780	COG0523	cobalamin synthesis protein
FNL83_RS00805	COG0431	NADPH-dependent FMN reductase
FNL83_RS00805	COG3976	FMN-binding domain protein
FNL83_RS00805	COG1053	succinate dehydrogenase
FNL83_RS00815	COG1028	Short-chain dehydrogenase reductase Sdr
FNL83_RS00820	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FNL83_RS00855	COG0601	transmembrane transport
FNL83_RS00865	COG0444	Belongs to the ABC transporter superfamily
FNL83_RS00870	COG1124	(ABC) transporter
FNL83_RS00880	COG1882	Formate acetyltransferase
FNL83_RS00885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FNL83_RS00890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNL83_RS00895	COG1114	Component of the transport system for branched-chain amino acids
FNL83_RS00900	COG1309	transcriptional regulator
FNL83_RS00905	COG3246	L-lysine catabolic process to acetate
FNL83_RS00910	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNL83_RS00945	COG1288	antiporter activity
FNL83_RS00950	COG0549	Belongs to the carbamate kinase family
FNL83_RS00955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNL83_RS00965	COG0346	lactoylglutathione lyase activity
FNL83_RS00970	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FNL83_RS00975	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FNL83_RS00985	COG2376	Dihydroxyacetone kinase
FNL83_RS00990	COG1461	Dihydroxyacetone kinase
FNL83_RS00995	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FNL83_RS01010	COG2814	Major facilitator Superfamily
FNL83_RS01045	COG2814	Major facilitator Superfamily
FNL83_RS01060	COG2962	Rard protein
FNL83_RS01065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNL83_RS01070	COG0471	metal ion transport
FNL83_RS01075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNL83_RS01080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNL83_RS01085	COG0022	dehydrogenase e1 component
FNL83_RS01090	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNL83_RS01110	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FNL83_RS01115	COG1054	Belongs to the UPF0176 family
FNL83_RS01120	COG3386	PFAM SMP-30 Gluconolaconase
FNL83_RS01125	COG2353	YceI-like domain
FNL83_RS01135	COG0579	oxidoreductase
FNL83_RS01160	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FNL83_RS01165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FNL83_RS01170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNL83_RS01175	COG0131	Imidazoleglycerol-phosphate dehydratase
FNL83_RS01180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNL83_RS01185	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FNL83_RS01190	COG0107	imidazoleglycerol-phosphate synthase activity
FNL83_RS01195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FNL83_RS01195	COG0140	phosphoribosyl-ATP diphosphatase activity
FNL83_RS01200	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FNL83_RS01230	COG2814	Major facilitator Superfamily
FNL83_RS01235	COG0737	Belongs to the 5'-nucleotidase family
FNL83_RS01250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FNL83_RS01255	COG3639	organic phosphonate transmembrane transporter activity
FNL83_RS01275	COG0201	protein transport
FNL83_RS01285	COG1073	alpha beta
FNL83_RS01295	COG0653	protein targeting
FNL83_RS01300	COG0438	transferase activity, transferring glycosyl groups
FNL83_RS01325	COG2814	Major facilitator Superfamily
FNL83_RS01345	COG1764	response to oxidative stress
FNL83_RS01355	COG3942	CHAP domain
FNL83_RS01355	COG1705	Flagellar rod assembly protein muramidase FlgJ
FNL83_RS01365	COG1482	cell wall glycoprotein biosynthetic process
FNL83_RS01370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNL83_RS01370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNL83_RS01370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNL83_RS01375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNL83_RS01375	COG3711	transcriptional antiterminator
FNL83_RS01410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNL83_RS01415	COG3227	Zinc metalloprotease (Elastase)
FNL83_RS01420	COG1438	arginine binding
FNL83_RS01425	COG2235	arginine
FNL83_RS01430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNL83_RS01440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNL83_RS01450	COG2843	Capsule synthesis protein
FNL83_RS01460	COG3961	Belongs to the TPP enzyme family
FNL83_RS01500	COG4195	phage-related replication protein
FNL83_RS01510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNL83_RS01515	COG0702	epimerase
FNL83_RS01520	COG1785	Belongs to the alkaline phosphatase family
FNL83_RS01535	COG2205	protein histidine kinase activity
FNL83_RS01540	COG1136	(ABC) transporter
FNL83_RS01555	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNL83_RS01580	COG1846	Transcriptional regulator
FNL83_RS01590	COG0386	Belongs to the glutathione peroxidase family
FNL83_RS01600	COG0175	sulfate reduction
FNL83_RS01605	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FNL83_RS01610	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNL83_RS01625	COG0730	response to heat
FNL83_RS01630	COG2046	Belongs to the sulfate adenylyltransferase family
FNL83_RS01635	COG0529	Catalyzes the synthesis of activated sulfate
FNL83_RS01645	COG1328	CTP reductase activity
FNL83_RS01650	COG0602	queuosine metabolic process
FNL83_RS01655	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FNL83_RS01670	COG1510	regulation of RNA biosynthetic process
FNL83_RS01675	COG1012	belongs to the aldehyde dehydrogenase family
FNL83_RS01680	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNL83_RS01685	COG1473	amidohydrolase
FNL83_RS01700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNL83_RS01705	COG0574	Belongs to the PEP-utilizing enzyme family
FNL83_RS01705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNL83_RS01710	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FNL83_RS01715	COG0579	oxidoreductase
FNL83_RS01725	COG3588	fructose-bisphosphate aldolase
FNL83_RS01735	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNL83_RS01770	COG0531	amino acid
FNL83_RS01775	COG0583	DNA-binding transcription factor activity
FNL83_RS01780	COG0039	L-malate dehydrogenase activity
FNL83_RS01785	COG0028	Belongs to the TPP enzyme family
FNL83_RS01790	COG3527	Alpha-acetolactate decarboxylase
FNL83_RS01800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FNL83_RS01805	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FNL83_RS01810	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FNL83_RS01825	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FNL83_RS01835	COG0167	dihydroorotate dehydrogenase activity
FNL83_RS01840	COG3001	Fructosamine kinase
FNL83_RS01845	COG1113	amino acid transport
FNL83_RS01865	COG0741	lytic transglycosylase activity
FNL83_RS01875	COG3942	CHAP domain
FNL83_RS01885	COG0436	Aminotransferase
FNL83_RS01895	COG2608	mercury ion transmembrane transporter activity
FNL83_RS01900	COG2217	Heavy metal translocating P-type atpase
FNL83_RS01910	COG1028	Short-chain dehydrogenase reductase Sdr
FNL83_RS01915	COG1012	belongs to the aldehyde dehydrogenase family
FNL83_RS01940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNL83_RS01945	COG3425	synthase
FNL83_RS01965	COG0583	DNA-binding transcription factor activity
FNL83_RS01970	COG1380	Effector of murein hydrolase LrgA
FNL83_RS01975	COG1346	cytolysis
FNL83_RS01980	COG0028	Belongs to the TPP enzyme family
FNL83_RS01985	COG2190	(PTS) system
FNL83_RS01985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNL83_RS01985	COG1263	PTS System
FNL83_RS02000	COG1063	alcohol dehydrogenase
FNL83_RS02010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNL83_RS02025	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FNL83_RS02035	COG2843	Capsule synthesis protein
FNL83_RS02050	COG4975	Glucose uptake
FNL83_RS02055	COG1869	D-ribose catabolic process
FNL83_RS02065	COG1070	Carbohydrate kinase
FNL83_RS02085	COG1760	l-serine dehydratase
FNL83_RS02090	COG1760	l-serine dehydratase
FNL83_RS02105	COG3764	Sortase (surface protein transpeptidase)
FNL83_RS02115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNL83_RS02120	COG0778	Nitroreductase
FNL83_RS02130	COG1012	belongs to the aldehyde dehydrogenase family
FNL83_RS02140	COG2514	catechol 2,3-dioxygenase activity
FNL83_RS02155	COG1012	belongs to the aldehyde dehydrogenase family
FNL83_RS02160	COG3949	Membrane
FNL83_RS02175	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FNL83_RS02180	COG0586	Pfam SNARE associated Golgi protein
FNL83_RS02185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNL83_RS02190	COG2022	thiamine diphosphate biosynthetic process
FNL83_RS02200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNL83_RS02210	COG2271	Major facilitator Superfamily
FNL83_RS02225	COG4876	unkown
FNL83_RS02230	COG2357	RelA SpoT domain protein
FNL83_RS02250	COG0789	Transcriptional regulator
FNL83_RS02255	COG2271	Major facilitator Superfamily
FNL83_RS02260	COG1802	Transcriptional regulator
FNL83_RS02270	COG2610	gluconate transmembrane transporter activity
FNL83_RS02275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNL83_RS02280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNL83_RS02285	COG0438	transferase activity, transferring glycosyl groups
FNL83_RS02305	COG4221	oxidoreductase activity
FNL83_RS02310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNL83_RS02315	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FNL83_RS02325	COG1028	Short-chain dehydrogenase reductase Sdr
FNL83_RS02335	COG1363	Peptidase, m42
FNL83_RS02345	COG0069	glutamate synthase activity
FNL83_RS02365	COG4619	ABC transporter
FNL83_RS02370	COG0390	transport system, permease component
FNL83_RS02375	COG2814	Major facilitator Superfamily
FNL83_RS02380	COG2272	Belongs to the type-B carboxylesterase lipase family
FNL83_RS02385	COG0531	amino acid
FNL83_RS02395	COG1063	alcohol dehydrogenase
FNL83_RS02415	COG1174	glycine betaine transport
FNL83_RS02420	COG1346	cytolysis
FNL83_RS02425	COG1380	Effector of murein hydrolase LrgA
FNL83_RS02430	COG3279	Response regulator of the LytR AlgR family
FNL83_RS02435	COG3275	phosphorelay sensor kinase activity
FNL83_RS02445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNL83_RS02450	COG0706	membrane insertase activity
FNL83_RS02460	COG0531	amino acid
FNL83_RS02465	COG1113	amino acid transport
FNL83_RS02490	COG1929	Belongs to the glycerate kinase type-1 family
FNL83_RS02505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FNL83_RS02510	COG0588	phosphoglycerate mutase activity
FNL83_RS02520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNL83_RS02525	COG0765	amino acid transport
FNL83_RS02530	COG1126	abc transporter atp-binding protein
FNL83_RS02535	COG2348	transferase activity, transferring amino-acyl groups
FNL83_RS02555	COG2116	formate transmembrane transporter activity
FNL83_RS02560	COG0454	-acetyltransferase
FNL83_RS02565	COG0747	negative chemotaxis
FNL83_RS02580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNL83_RS02585	COG2146	nitrite reductase [NAD(P)H] activity
FNL83_RS02595	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FNL83_RS02600	COG1140	nitrate reductase beta subunit
FNL83_RS02610	COG2181	nitrate reductase activity
FNL83_RS02620	COG4585	Histidine kinase
FNL83_RS02625	COG2197	response regulator
FNL83_RS02630	COG2223	nitrite transmembrane transporter activity
FNL83_RS02635	COG1846	Transcriptional regulator
FNL83_RS02640	COG0778	Nitroreductase
FNL83_RS02660	COG3871	stress protein (general stress protein 26)
FNL83_RS02675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNL83_RS02675	COG1263	PTS System
FNL83_RS02710	COG0604	alcohol dehydrogenase
FNL83_RS02715	COG0456	acetyltransferase
FNL83_RS02720	COG0463	Glycosyl transferase, family 2
FNL83_RS02720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNL83_RS02730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNL83_RS02730	COG0463	Glycosyl transferase, family 2
FNL83_RS02735	COG1620	l-lactate permease
FNL83_RS02740	COG0438	transferase activity, transferring glycosyl groups
FNL83_RS02745	COG0579	oxidoreductase
FNL83_RS02750	COG5002	protein histidine kinase activity
FNL83_RS02750	COG3850	Histidine kinase
FNL83_RS02755	COG0745	RESPONSE REGULATOR receiver
FNL83_RS02760	COG0577	efflux transmembrane transporter activity
FNL83_RS02765	COG1136	(ABC) transporter
FNL83_RS02780	COG4640	response to antibiotic
FNL83_RS02785	COG2814	Major facilitator Superfamily
FNL83_RS02795	COG1566	PFAM secretion protein HlyD family protein
FNL83_RS02800	COG2814	Major facilitator Superfamily
FNL83_RS02815	COG0657	acetylesterase activity
FNL83_RS02830	COG0598	Magnesium transport protein CorA
FNL83_RS02835	COG1304	FMN binding
FNL83_RS02840	COG0786	glutamate:sodium symporter activity
FNL83_RS02860	COG2094	Belongs to the DNA glycosylase MPG family
FNL83_RS02885	COG1069	ribulokinase activity
FNL83_RS02890	COG2017	converts alpha-aldose to the beta-anomer
FNL83_RS02895	COG2258	MOSC domain
FNL83_RS02900	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FNL83_RS02915	COG1266	CAAX protease self-immunity
FNL83_RS02920	COG0010	Belongs to the arginase family
FNL83_RS02925	COG1473	amidohydrolase
FNL83_RS02930	COG1028	Short-chain dehydrogenase reductase Sdr
FNL83_RS02935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNL83_RS02960	COG1737	Transcriptional regulator
FNL83_RS02965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNL83_RS02965	COG1263	PTS System
FNL83_RS02975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNL83_RS03000	COG1113	amino acid transport
FNL83_RS03010	COG1263	PTS System
FNL83_RS03010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNL83_RS03015	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNL83_RS03030	COG1266	CAAX protease self-immunity
FNL83_RS03035	COG2378	regulation of single-species biofilm formation
FNL83_RS03040	COG0483	inositol monophosphate 1-phosphatase activity
FNL83_RS03045	COG1316	TRANSCRIPTIONal
FNL83_RS03075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNL83_RS03080	COG2076	Multidrug Resistance protein
FNL83_RS03085	COG2076	Multidrug Resistance protein
FNL83_RS03090	COG3942	CHAP domain
FNL83_RS03105	COG1757	Na H antiporter
FNL83_RS03110	COG3942	CHAP domain
FNL83_RS03135	COG0829	nickel cation binding
FNL83_RS03140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNL83_RS03145	COG0830	nickel cation binding
FNL83_RS03150	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FNL83_RS03155	COG0804	urea catabolic process
FNL83_RS03160	COG0832	Belongs to the urease beta subunit family
FNL83_RS03165	COG0831	urea catabolic process
FNL83_RS03180	COG1960	acyl-CoA dehydrogenase activity
FNL83_RS03185	COG1957	nucleoside hydrolase
FNL83_RS03190	COG1268	BioY protein
FNL83_RS03200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNL83_RS03210	COG0725	ABC transporter, periplasmic molybdate-binding protein
FNL83_RS03215	COG4149	molybdate abc transporter
FNL83_RS03220	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FNL83_RS03225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNL83_RS03230	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNL83_RS03235	COG0315	cyclic pyranopterin monophosphate synthase activity
FNL83_RS03240	COG0303	'Molybdopterin
FNL83_RS03250	COG0314	molybdopterin synthase activity
FNL83_RS03260	COG0746	molybdenum cofactor guanylyltransferase activity
FNL83_RS03265	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FNL83_RS03300	COG2348	transferase activity, transferring amino-acyl groups
FNL83_RS03305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNL83_RS03325	COG1028	Short-chain dehydrogenase reductase Sdr
FNL83_RS03330	COG4975	Glucose uptake
FNL83_RS03335	COG0551	DNA topoisomerase type I activity
FNL83_RS03335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNL83_RS03340	COG2252	PERMEase
FNL83_RS03355	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNL83_RS03360	COG0088	Forms part of the polypeptide exit tunnel
FNL83_RS03365	COG0089	rRNA binding
FNL83_RS03370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FNL83_RS03375	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FNL83_RS03380	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNL83_RS03385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FNL83_RS03390	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FNL83_RS03400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FNL83_RS03405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FNL83_RS03410	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FNL83_RS03415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FNL83_RS03420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNL83_RS03425	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FNL83_RS03430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FNL83_RS03435	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FNL83_RS03440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FNL83_RS03445	COG1841	ribosomal large subunit assembly
FNL83_RS03450	COG0200	Binds to the 23S rRNA
FNL83_RS03455	COG0201	protein transport
FNL83_RS03460	COG0563	adenylate kinase activity
FNL83_RS03465	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FNL83_RS03470	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FNL83_RS03475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNL83_RS03480	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FNL83_RS03485	COG0202	RNA polymerase activity
FNL83_RS03490	COG0203	ribosomal protein L17
FNL83_RS03495	COG1122	ATPase activity
FNL83_RS03500	COG1122	ATPase activity
FNL83_RS03510	COG0101	tRNA pseudouridine synthase activity
FNL83_RS03515	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNL83_RS03520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FNL83_RS03525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNL83_RS03530	COG1349	DNA-binding transcription factor activity
FNL83_RS03535	COG0698	ribose 5-phosphate isomerase
FNL83_RS03540	COG0698	ribose 5-phosphate isomerase
FNL83_RS03545	COG1105	Belongs to the carbohydrate kinase PfkB family
FNL83_RS03550	COG3684	Belongs to the aldolase LacD family
FNL83_RS03555	COG1447	Phosphotransferase system cellobiose-specific component IIA
FNL83_RS03560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FNL83_RS03560	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FNL83_RS03565	COG2723	6-phospho-beta-galactosidase activity
FNL83_RS03575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNL83_RS03580	COG2130	NADP-dependent
FNL83_RS03585	COG0604	alcohol dehydrogenase
FNL83_RS03600	COG1302	Protein conserved in bacteria
FNL83_RS03605	COG4264	IucA IucC family
FNL83_RS03610	COG2814	Major facilitator Superfamily
FNL83_RS03615	COG4264	IucA IucC family
FNL83_RS03620	COG3457	Alanine racemase
FNL83_RS03625	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FNL83_RS03630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNL83_RS03635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNL83_RS03640	COG3314	Sporulation integral membrane protein YlbJ
FNL83_RS03645	COG2329	Antibiotic biosynthesis monooxygenase
FNL83_RS03655	COG1988	membrane-bound metal-dependent
FNL83_RS03660	COG4284	Utp--glucose-1-phosphate uridylyltransferase
FNL83_RS03680	COG2814	Major facilitator Superfamily
FNL83_RS03685	COG0489	protein tyrosine kinase activity
FNL83_RS03735	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FNL83_RS03745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNL83_RS03750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNL83_RS03755	COG0561	phosphatase activity
FNL83_RS03775	COG0640	Transcriptional regulator
FNL83_RS03780	COG0702	epimerase
FNL83_RS03790	COG1482	cell wall glycoprotein biosynthetic process
FNL83_RS03815	COG0783	Belongs to the Dps family
FNL83_RS03820	COG0813	purine-nucleoside phosphorylase activity
FNL83_RS03825	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FNL83_RS03830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FNL83_RS03835	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FNL83_RS03845	COG1854	S-ribosylhomocysteine lyase activity
FNL83_RS03865	COG5146	pantothenate kinase activity
FNL83_RS03875	COG3343	RNA polymerase activity
FNL83_RS03880	COG0504	CTP synthase activity
FNL83_RS03890	COG0191	fructose-bisphosphate aldolase activity
FNL83_RS03895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNL83_RS03900	COG1012	belongs to the aldehyde dehydrogenase family
FNL83_RS03905	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FNL83_RS03910	COG0254	rRNA binding
FNL83_RS03920	COG1435	thymidine kinase activity
FNL83_RS03925	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FNL83_RS03930	COG2890	protein-(glutamine-N5) methyltransferase activity
FNL83_RS03940	COG0009	L-threonylcarbamoyladenylate synthase
FNL83_RS03945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNL83_RS03950	COG4475	Protein of unknown function (DUF436)
FNL83_RS03955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNL83_RS03960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FNL83_RS03965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FNL83_RS03975	COG0356	it plays a direct role in the translocation of protons across the membrane
FNL83_RS03985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNL83_RS03990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNL83_RS03995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FNL83_RS04000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNL83_RS04005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FNL83_RS04010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FNL83_RS04020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNL83_RS04025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNL83_RS04035	COG0629	single-stranded DNA binding
FNL83_RS04040	COG1388	LysM domain
FNL83_RS04045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FNL83_RS04055	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FNL83_RS04060	COG0352	thiamine-phosphate diphosphorylase activity
FNL83_RS04065	COG0706	membrane insertase activity
FNL83_RS04070	COG1418	mRNA catabolic process
FNL83_RS04075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNL83_RS04080	COG1937	Protein conserved in bacteria
FNL83_RS04095	COG0772	Belongs to the SEDS family
FNL83_RS04100	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNL83_RS04105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FNL83_RS04110	COG0513	Belongs to the DEAD box helicase family
FNL83_RS04120	COG3428	Bacterial PH domain
FNL83_RS04125	COG3402	PFAM membrane-flanked domain
FNL83_RS04130	COG0736	holo-[acyl-carrier-protein] synthase activity
FNL83_RS04135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNL83_RS04145	COG2337	Toxic component of a toxin-antitoxin (TA) module
FNL83_RS04150	COG2208	phosphoserine phosphatase activity
FNL83_RS04165	COG1191	sigma factor activity
FNL83_RS04170	COG2183	response to ionizing radiation
FNL83_RS04175	COG3091	SprT-like family
FNL83_RS04215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNL83_RS04220	COG0066	3-isopropylmalate dehydratase activity
FNL83_RS04225	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNL83_RS04230	COG0473	3-isopropylmalate dehydrogenase activity
FNL83_RS04235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNL83_RS04240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FNL83_RS04250	COG0028	Belongs to the TPP enzyme family
FNL83_RS04255	COG0129	dihydroxy-acid dehydratase activity
FNL83_RS04260	COG0802	atpase or kinase
FNL83_RS04265	COG1214	PFAM Peptidase M22, glycoprotease
FNL83_RS04270	COG0456	acetyltransferase
FNL83_RS04275	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FNL83_RS04280	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNL83_RS04285	COG0488	(ABC) transporter
FNL83_RS04290	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FNL83_RS04300	COG2391	methyltransferase activity
FNL83_RS04305	COG0425	Belongs to the sulfur carrier protein TusA family
FNL83_RS04310	COG0004	ammonium transporteR
FNL83_RS04315	COG1609	Transcriptional regulator
FNL83_RS04325	COG1621	beta-fructofuranosidase activity
FNL83_RS04330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNL83_RS04335	COG3279	Response regulator of the LytR AlgR family
FNL83_RS04340	COG3290	protein histidine kinase activity
FNL83_RS04375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNL83_RS04380	COG0459	protein refolding
FNL83_RS04400	COG1725	Transcriptional regulator
FNL83_RS04405	COG1131	(ABC) transporter
FNL83_RS04415	COG1131	(ABC) transporter
FNL83_RS04465	COG4974	Belongs to the 'phage' integrase family
FNL83_RS04495	COG3682	Transcriptional regulator
FNL83_RS04505	COG2706	6-phosphogluconolactonase activity
FNL83_RS04510	COG1012	belongs to the aldehyde dehydrogenase family
FNL83_RS04515	COG1227	inorganic diphosphatase activity
FNL83_RS04520	COG1335	isochorismatase
FNL83_RS04530	COG0077	Prephenate dehydratase
FNL83_RS04540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FNL83_RS04545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FNL83_RS04550	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FNL83_RS04560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNL83_RS04565	COG4496	protein, YerC YecD
FNL83_RS04570	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FNL83_RS04575	COG0210	DNA helicase
FNL83_RS04580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNL83_RS04585	COG4851	CamS sex pheromone cAM373 precursor
FNL83_RS04590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNL83_RS04595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNL83_RS04600	COG0154	amidase activity
FNL83_RS04605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNL83_RS04610	COG1597	lipid kinase activity
FNL83_RS04615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNL83_RS04625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNL83_RS04635	COG1528	Iron-storage protein
FNL83_RS04655	COG4129	membrane
FNL83_RS04660	COG0024	Methionine aminopeptidase
FNL83_RS04675	COG4585	Histidine kinase
FNL83_RS04680	COG2197	response regulator
FNL83_RS04685	COG1295	ribonuclease BN
FNL83_RS04695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNL83_RS04700	COG4840	Belongs to the UPF0435 family
FNL83_RS04705	COG2309	aminopeptidase activity
FNL83_RS04710	COG1607	acyl-coa hydrolase
FNL83_RS04715	COG0535	radical SAM domain protein
FNL83_RS04725	COG0693	protein deglycase activity
FNL83_RS04730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNL83_RS04735	COG2137	regulation of response to DNA damage stimulus
FNL83_RS04745	COG1134	teichoic acid transport
FNL83_RS04745	COG1388	LysM domain
FNL83_RS04755	COG1988	membrane-bound metal-dependent
FNL83_RS04765	COG3557	Belongs to the UPF0374 family
FNL83_RS04775	COG4129	membrane
FNL83_RS04780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNL83_RS04785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FNL83_RS04790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNL83_RS04795	COG0735	belongs to the Fur family
FNL83_RS04955	COG0765	amino acid transport
FNL83_RS04960	COG1126	abc transporter atp-binding protein
FNL83_RS04965	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FNL83_RS04990	COG0114	fumarate hydratase activity
FNL83_RS04995	COG0564	pseudouridine synthase activity
FNL83_RS05000	COG4585	Histidine kinase
FNL83_RS05000	COG2203	Gaf domain
FNL83_RS05005	COG2197	response regulator
FNL83_RS05015	COG4399	Belongs to the UPF0754 family
FNL83_RS05020	COG3679	Belongs to the UPF0342 family
FNL83_RS05025	COG0420	3'-5' exonuclease activity
FNL83_RS05035	COG3481	metal-dependent phosphohydrolase, HD sub domain
FNL83_RS05045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNL83_RS05060	COG0537	adenosine 5'-monophosphoramidase activity
FNL83_RS05065	COG1131	(ABC) transporter
FNL83_RS05070	COG4473	ABC transporter
FNL83_RS05080	COG2329	Antibiotic biosynthesis monooxygenase
FNL83_RS05085	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FNL83_RS05090	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FNL83_RS05095	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNL83_RS05195	COG0318	PFAM AMP-dependent synthetase and ligase
FNL83_RS05205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FNL83_RS05210	COG0494	nUDIX hydrolase
FNL83_RS05215	COG1506	peptidase
FNL83_RS05220	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FNL83_RS05225	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNL83_RS05235	COG0656	L-ascorbic acid biosynthetic process
FNL83_RS05245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNL83_RS05250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNL83_RS05260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNL83_RS05290	COG4193	domain, Protein
FNL83_RS05290	COG5632	N-Acetylmuramoyl-L-alanine amidase
FNL83_RS05290	COG3266	domain, Protein
FNL83_RS05300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNL83_RS05300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNL83_RS05310	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNL83_RS05310	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNL83_RS05315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FNL83_RS05320	COG0506	proline dehydrogenase activity
FNL83_RS05325	COG2267	carboxylic ester hydrolase activity
FNL83_RS05335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FNL83_RS05340	COG1242	4 iron, 4 sulfur cluster binding
FNL83_RS05345	COG2814	Major facilitator Superfamily
FNL83_RS05350	COG0495	leucyl-tRNA aminoacylation
FNL83_RS05365	COG2081	HI0933 family
FNL83_RS05370	COG2244	polysaccharide biosynthetic process
FNL83_RS05375	COG1187	pseudouridine synthase activity
FNL83_RS05385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNL83_RS05390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNL83_RS05395	COG0510	thiamine kinase activity
FNL83_RS05400	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNL83_RS05410	COG1363	Peptidase, m42
FNL83_RS05415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNL83_RS05420	COG4848	Belongs to the UPF0354 family
FNL83_RS05425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNL83_RS05430	COG1674	ftsk spoiiie
FNL83_RS05435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNL83_RS05440	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FNL83_RS05450	COG1605	Chorismate mutase
FNL83_RS05450	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FNL83_RS05455	COG1609	Transcriptional regulator
FNL83_RS05460	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FNL83_RS05470	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FNL83_RS05475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNL83_RS05480	COG0204	Acyl-transferase
FNL83_RS05485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNL83_RS05485	COG1263	PTS System
FNL83_RS05495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNL83_RS05500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNL83_RS05505	COG1764	response to oxidative stress
FNL83_RS05510	COG0584	glycerophosphoryl diester phosphodiesterase
FNL83_RS05515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FNL83_RS05525	COG1956	GAF domain-containing protein
FNL83_RS05530	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FNL83_RS05540	COG0301	tRNA thio-modification
FNL83_RS05550	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FNL83_RS05555	COG0827	DNA restriction-modification system
FNL83_RS05560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FNL83_RS05565	COG0589	response to stress
FNL83_RS05570	COG0686	Belongs to the AlaDH PNT family
FNL83_RS05575	COG0006	proline dipeptidase activity
FNL83_RS05580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNL83_RS05590	COG4109	DRTGG domain
FNL83_RS05595	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FNL83_RS05600	COG0587	DNA-directed DNA polymerase activity
FNL83_RS05605	COG0281	malic enzyme
FNL83_RS05610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FNL83_RS05615	COG0825	malonyl-CoA metabolic process
FNL83_RS05620	COG0205	6-phosphofructokinase activity
FNL83_RS05625	COG0469	pyruvate kinase activity
FNL83_RS05630	COG1113	amino acid transport
FNL83_RS05635	COG0372	Belongs to the citrate synthase family
FNL83_RS05640	COG0538	isocitrate dehydrogenase activity
FNL83_RS05645	COG0745	RESPONSE REGULATOR receiver
FNL83_RS05650	COG5002	protein histidine kinase activity
FNL83_RS05655	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNL83_RS05655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNL83_RS05660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNL83_RS05665	COG0237	dephospho-CoA kinase activity
FNL83_RS05675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNL83_RS05685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FNL83_RS05690	COG3611	Membrane attachment protein
FNL83_RS05695	COG1484	DNA-dependent DNA replication
FNL83_RS05700	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNL83_RS05705	COG0833	amino acid
FNL83_RS05710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNL83_RS05715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FNL83_RS05720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNL83_RS05725	COG4112	unkown
FNL83_RS05735	COG0544	peptidyl-prolyl cis-trans isomerase activity
FNL83_RS05740	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FNL83_RS05745	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FNL83_RS05750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FNL83_RS05760	COG0181	hydroxymethylbilane synthase activity
FNL83_RS05770	COG0113	porphobilinogen synthase activity
FNL83_RS05775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNL83_RS05785	COG2818	Glycosylase
FNL83_RS05790	COG0525	valine-tRNA ligase activity
FNL83_RS05795	COG0285	dihydrofolate synthase activity
FNL83_RS05805	COG2003	Belongs to the UPF0758 family
FNL83_RS05835	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FNL83_RS05840	COG2868	ribosomal protein
FNL83_RS05845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FNL83_RS05850	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNL83_RS05855	COG4492	Belongs to the UPF0735 family
FNL83_RS05860	COG0632	four-way junction helicase activity
FNL83_RS05865	COG2255	four-way junction helicase activity
FNL83_RS05870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNL83_RS05875	COG0343	queuine tRNA-ribosyltransferase activity
FNL83_RS05880	COG1862	Preprotein translocase
FNL83_RS05885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNL83_RS05885	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNL83_RS05890	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FNL83_RS05890	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FNL83_RS05895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNL83_RS05905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNL83_RS05910	COG1490	D-aminoacyl-tRNA deacylase activity
FNL83_RS05915	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNL83_RS05920	COG0124	histidyl-tRNA synthetase
FNL83_RS05925	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FNL83_RS05935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FNL83_RS05940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FNL83_RS05945	COG1959	2 iron, 2 sulfur cluster binding
FNL83_RS05955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNL83_RS05960	COG1104	cysteine desulfurase activity
FNL83_RS05965	COG0482	sulfurtransferase activity
FNL83_RS05975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNL83_RS05980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNL83_RS05985	COG4472	Bacterial protein of unknown function (DUF965)
FNL83_RS05990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FNL83_RS05995	COG3906	Belongs to the UPF0473 family
FNL83_RS06005	COG0826	peptidase U32
FNL83_RS06010	COG0826	peptidase U32
FNL83_RS06015	COG0572	uridine kinase
FNL83_RS06020	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNL83_RS06030	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNL83_RS06035	COG1984	allophanate hydrolase subunit 2
FNL83_RS06040	COG0511	ligase activity, forming carbon-carbon bonds
FNL83_RS06045	COG0439	Biotin carboxylase
FNL83_RS06050	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FNL83_RS06055	COG1914	H( )-stimulated, divalent metal cation uptake system
FNL83_RS06060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNL83_RS06065	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FNL83_RS06070	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FNL83_RS06075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNL83_RS06080	COG1534	Rna-binding protein
FNL83_RS06085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FNL83_RS06090	COG1713	HD superfamily hydrolase involved in NAD metabolism
FNL83_RS06095	COG0799	negative regulation of ribosome biogenesis
FNL83_RS06100	COG2226	methyltransferase
FNL83_RS06110	COG2131	deaminase
FNL83_RS06115	COG0658	competence protein
FNL83_RS06115	COG2333	competence protein COMEC
FNL83_RS06120	COG1466	dna polymerase III delta subunit
FNL83_RS06125	COG0268	Binds directly to 16S ribosomal RNA
FNL83_RS06130	COG0481	GTPase activity
FNL83_RS06135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNL83_RS06140	COG1420	regulation of RNA biosynthetic process
FNL83_RS06145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNL83_RS06150	COG0443	Heat shock 70 kDa protein
FNL83_RS06155	COG0484	heat shock protein binding
FNL83_RS06160	COG2264	protein methyltransferase activity
FNL83_RS06165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FNL83_RS06170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNL83_RS06180	COG1030	water channel activity
FNL83_RS06185	COG4864	UPF0365 protein
FNL83_RS06195	COG1702	phosphate starvation-inducible protein PhoH
FNL83_RS06200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNL83_RS06205	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FNL83_RS06210	COG0295	cytidine deaminase activity
FNL83_RS06215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FNL83_RS06220	COG1381	Involved in DNA repair and RecF pathway recombination
FNL83_RS06225	COG0423	glycine-tRNA ligase activity
FNL83_RS06230	COG0517	IMP dehydrogenase activity
FNL83_RS06235	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FNL83_RS06240	COG0358	DNA primase activity
FNL83_RS06245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNL83_RS06250	COG2384	SAM-dependent methyltransferase
FNL83_RS06255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FNL83_RS06260	COG0513	Belongs to the DEAD box helicase family
FNL83_RS06265	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FNL83_RS06270	COG1121	(ABC) transporter
FNL83_RS06275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNL83_RS06280	COG0735	belongs to the Fur family
FNL83_RS06285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNL83_RS06295	COG0768	penicillin binding
FNL83_RS06300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNL83_RS06305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FNL83_RS06315	COG4483	Protein conserved in bacteria
FNL83_RS06320	COG1940	carbohydrate kinase activity
FNL83_RS06325	COG0011	TIGRFAM Protein of
FNL83_RS06335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FNL83_RS06340	COG1459	type II secretion system
FNL83_RS06345	COG4537	Required for transformation and DNA binding
FNL83_RS06370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNL83_RS06375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNL83_RS06380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNL83_RS06385	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNL83_RS06395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNL83_RS06400	COG0095	Lipoate-protein ligase
FNL83_RS06415	COG0006	proline dipeptidase activity
FNL83_RS06420	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNL83_RS06425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FNL83_RS06430	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FNL83_RS06435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNL83_RS06440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNL83_RS06445	COG0511	ligase activity, forming carbon-carbon bonds
FNL83_RS06450	COG0439	Biotin carboxylase
FNL83_RS06455	COG1302	Protein conserved in bacteria
FNL83_RS06460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNL83_RS06465	COG1570	exodeoxyribonuclease VII activity
FNL83_RS06470	COG1722	exodeoxyribonuclease VII activity
FNL83_RS06480	COG1438	arginine binding
FNL83_RS06485	COG0497	DNA recombination
FNL83_RS06490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNL83_RS06495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNL83_RS06500	COG0022	dehydrogenase e1 component
FNL83_RS06505	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNL83_RS06515	COG4129	membrane
FNL83_RS06520	COG2195	Cleaves the N-terminal amino acid of tripeptides
FNL83_RS06525	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNL83_RS06530	COG0366	Alpha amylase catalytic
FNL83_RS06545	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNL83_RS06550	COG1234	tRNA 3'-trailer cleavage
FNL83_RS06555	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNL83_RS06560	COG1028	Short-chain dehydrogenase reductase Sdr
FNL83_RS06565	COG0667	Aldo Keto reductase
FNL83_RS06570	COG0494	nUDIX hydrolase
FNL83_RS06575	COG0735	belongs to the Fur family
FNL83_RS06580	COG4974	Belongs to the 'phage' integrase family
FNL83_RS06585	COG1547	Domain of unknown function (DUF309)
FNL83_RS06590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FNL83_RS06595	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FNL83_RS06600	COG1187	pseudouridine synthase activity
FNL83_RS06605	COG0745	RESPONSE REGULATOR receiver
FNL83_RS06625	COG1141	Ferredoxin
FNL83_RS06635	COG0514	ATP-dependent DNA helicase (RecQ)
FNL83_RS06640	COG1388	LysM domain
FNL83_RS06645	COG0492	ferredoxin-NADP+ reductase activity
FNL83_RS06650	COG0252	asparaginase activity
FNL83_RS06655	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNL83_RS06660	COG0539	negative regulation of cytoplasmic translation
FNL83_RS06665	COG1160	GTP binding
FNL83_RS06670	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNL83_RS06685	COG2226	methyltransferase
FNL83_RS06695	COG0105	UTP biosynthetic process
FNL83_RS06700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FNL83_RS06705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FNL83_RS06710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNL83_RS06720	COG5582	Belongs to the UPF0302 family
FNL83_RS06725	COG4347	Protein of unknown function (DUF1405)
FNL83_RS06730	COG2738	Putative neutral zinc metallopeptidase
FNL83_RS06735	COG1694	Mazg nucleotide pyrophosphohydrolase
FNL83_RS06740	COG0438	transferase activity, transferring glycosyl groups
FNL83_RS06745	COG0617	tRNA 3'-terminal CCA addition
FNL83_RS06750	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FNL83_RS06750	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FNL83_RS06755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNL83_RS06755	COG1199	ATP-dependent helicase activity
FNL83_RS06760	COG0017	Asparaginyl-tRNA synthetase
FNL83_RS06765	COG3935	DnaD domain protein
FNL83_RS06770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FNL83_RS06780	COG4499	WXG100 protein secretion system (Wss), protein YukC
FNL83_RS06780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNL83_RS06785	COG3331	DNA recombination
FNL83_RS06795	COG4474	Belongs to the UPF0398 family
FNL83_RS06800	COG3599	regulation of cell shape
FNL83_RS06810	COG0116	Belongs to the methyltransferase superfamily
FNL83_RS06820	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FNL83_RS06825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNL83_RS06830	COG1196	nuclear chromosome segregation
FNL83_RS06830	COG1511	domain protein
FNL83_RS06830	COG4372	Transposase
FNL83_RS06840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FNL83_RS06850	COG1413	lyase activity
FNL83_RS06865	COG1136	(ABC) transporter
FNL83_RS06890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNL83_RS06895	COG2190	(PTS) system
FNL83_RS06900	COG4479	Belongs to the UPF0346 family
FNL83_RS06905	COG0793	Belongs to the peptidase S41A family
FNL83_RS06920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNL83_RS06925	COG0671	phosphoesterase, PA-phosphatase related
FNL83_RS06930	COG3842	ATPase activity
FNL83_RS06935	COG4209	transmembrane transport
FNL83_RS06945	COG0395	ABC-type sugar transport system, permease component
FNL83_RS06955	COG0534	Mate efflux family protein
FNL83_RS06960	COG1349	DNA-binding transcription factor activity
FNL83_RS06970	COG0745	RESPONSE REGULATOR receiver
FNL83_RS06975	COG5002	protein histidine kinase activity
FNL83_RS06985	COG0567	Dehydrogenase, E1 component
FNL83_RS06990	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNL83_RS07010	COG0714	Associated with various cellular activities
FNL83_RS07015	COG4548	von Willebrand factor, type A
FNL83_RS07020	COG1114	Component of the transport system for branched-chain amino acids
FNL83_RS07025	COG3853	Toxic anion resistance protein (TelA)
FNL83_RS07035	COG1254	Belongs to the acylphosphatase family
FNL83_RS07045	COG1278	Cold shock
FNL83_RS07060	COG1131	(ABC) transporter
FNL83_RS07080	COG1473	amidohydrolase
FNL83_RS07085	COG2171	N-acyltransferase activity
FNL83_RS07090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNL83_RS07095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNL83_RS07100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FNL83_RS07105	COG0527	aspartate kinase activity
FNL83_RS07110	COG0488	(ABC) transporter
FNL83_RS07115	COG2996	Protein conserved in bacteria
FNL83_RS07120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FNL83_RS07125	COG0573	inorganic phosphate transmembrane transporter activity
FNL83_RS07130	COG0581	inorganic phosphate transmembrane transporter activity
FNL83_RS07135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNL83_RS07140	COG0704	Plays a role in the regulation of phosphate uptake
FNL83_RS07180	COG2348	transferase activity, transferring amino-acyl groups
FNL83_RS07185	COG2348	transferase activity, transferring amino-acyl groups
FNL83_RS07200	COG0159	tryptophan synthase activity
FNL83_RS07205	COG0133	tryptophan synthase activity
FNL83_RS07210	COG0135	phosphoribosylanthranilate isomerase activity
FNL83_RS07215	COG0134	indole-3-glycerol-phosphate synthase activity
FNL83_RS07220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNL83_RS07225	COG0512	Glutamine amidotransferase of anthranilate synthase
FNL83_RS07225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNL83_RS07230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNL83_RS07235	COG0287	Prephenate dehydrogenase
FNL83_RS07240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNL83_RS07245	COG1942	4-Oxalocrotonate Tautomerase
FNL83_RS07265	COG0392	lysyltransferase activity
FNL83_RS07265	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FNL83_RS07270	COG0628	permease
FNL83_RS07275	COG3711	transcriptional antiterminator
FNL83_RS07280	COG1115	amino acid carrier protein
FNL83_RS07285	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNL83_RS07290	COG0187	DNA topoisomerase II activity
FNL83_RS07295	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FNL83_RS07300	COG4841	protein insertion into membrane
FNL83_RS07305	COG0824	Thioesterase
FNL83_RS07310	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FNL83_RS07315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FNL83_RS07320	COG1970	mechanosensitive ion channel activity
FNL83_RS07325	COG0419	ATPase involved in DNA repair
FNL83_RS07330	COG0420	3'-5' exonuclease activity
FNL83_RS07335	COG4846	Membrane protein involved in cytochrome C biogenesis
FNL83_RS07345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FNL83_RS07350	COG4224	UPF0291 protein
FNL83_RS07360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNL83_RS07370	COG2340	Cysteine-rich secretory protein family
FNL83_RS07375	COG0516	GMP reductase activity
FNL83_RS07380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNL83_RS07390	COG0753	catalase activity
FNL83_RS07395	COG0833	amino acid
FNL83_RS07410	COG0083	homoserine kinase activity
FNL83_RS07415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNL83_RS07420	COG0460	homoserine dehydrogenase
FNL83_RS07425	COG0527	aspartate kinase activity
FNL83_RS07440	COG1525	nuclease
FNL83_RS07450	COG2197	response regulator
FNL83_RS07455	COG4585	Histidine kinase
FNL83_RS07465	COG1131	(ABC) transporter
FNL83_RS07470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNL83_RS07505	COG0174	glutamine synthetase
FNL83_RS07510	COG0789	Transcriptional regulator
FNL83_RS07515	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FNL83_RS07520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNL83_RS07525	COG0386	Belongs to the glutathione peroxidase family
FNL83_RS07530	COG1923	regulation of RNA biosynthetic process
FNL83_RS07535	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNL83_RS07545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNL83_RS07550	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNL83_RS07555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNL83_RS07560	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FNL83_RS07565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FNL83_RS07570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNL83_RS07580	COG4550	Control of competence regulator ComK, YlbF/YmcA
FNL83_RS07585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNL83_RS07595	COG4195	phage-related replication protein
FNL83_RS07600	COG1013	pyruvate-flavodoxin oxidoreductase activity
FNL83_RS07605	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNL83_RS07605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNL83_RS07610	COG1692	metallophosphoesterase
FNL83_RS07620	COG1418	mRNA catabolic process
FNL83_RS07625	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNL83_RS07635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNL83_RS07650	COG0300	oxidoreductase activity
FNL83_RS07655	COG0612	Peptidase, M16
FNL83_RS07660	COG0612	Peptidase, M16
FNL83_RS07665	COG2188	Transcriptional regulator
FNL83_RS07670	COG1674	ftsk spoiiie
FNL83_RS07675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FNL83_RS07680	COG1185	polyribonucleotide nucleotidyltransferase activity
FNL83_RS07685	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FNL83_RS07690	COG0196	riboflavin kinase activity
FNL83_RS07695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FNL83_RS07700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FNL83_RS07705	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FNL83_RS07710	COG1358	cellular component organization or biogenesis
FNL83_RS07715	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FNL83_RS07720	COG0195	Participates in both transcription termination and antitermination
FNL83_RS07725	COG0779	Required for maturation of 30S ribosomal subunits
FNL83_RS07730	COG2176	DNA-directed DNA polymerase activity
FNL83_RS07735	COG0442	prolyl-tRNA aminoacylation
FNL83_RS07745	COG4589	Belongs to the CDS family
FNL83_RS07750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNL83_RS07755	COG0233	cytoplasmic translational termination
FNL83_RS07760	COG0528	UMP kinase activity
FNL83_RS07765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FNL83_RS07770	COG0052	Belongs to the universal ribosomal protein uS2 family
FNL83_RS07775	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FNL83_RS07780	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FNL83_RS07785	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FNL83_RS07790	COG4974	Belongs to the 'phage' integrase family
FNL83_RS07795	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FNL83_RS07800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNL83_RS07805	COG0758	DNA mediated transformation
FNL83_RS07810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FNL83_RS07815	COG0045	succinate-CoA ligase (ADP-forming) activity
FNL83_RS07820	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNL83_RS07835	COG4485	Bacterial membrane protein, YfhO
FNL83_RS07845	COG0335	large ribosomal subunit rRNA binding
FNL83_RS07850	COG0336	Belongs to the RNA methyltransferase TrmD family
FNL83_RS07855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNL83_RS07860	COG0228	four-way junction DNA binding
FNL83_RS07865	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FNL83_RS07870	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FNL83_RS07875	COG0552	protein localization to endoplasmic reticulum
FNL83_RS07880	COG1196	nuclear chromosome segregation
FNL83_RS07885	COG0571	ribonuclease III activity
FNL83_RS07890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNL83_RS07895	COG1028	Short-chain dehydrogenase reductase Sdr
FNL83_RS07905	COG0416	fatty acid biosynthetic process
FNL83_RS07910	COG1349	DNA-binding transcription factor activity
FNL83_RS07915	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FNL83_RS07920	COG1461	Dihydroxyacetone kinase
FNL83_RS07925	COG1302	Protein conserved in bacteria
FNL83_RS07930	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNL83_RS07940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNL83_RS07945	COG1162	GTPase activity
FNL83_RS07955	COG0631	protein serine/threonine phosphatase activity
FNL83_RS07960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNL83_RS07965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNL83_RS07965	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FNL83_RS07970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNL83_RS07975	COG0242	peptide deformylase activity
FNL83_RS07985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FNL83_RS07990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNL83_RS07995	COG1758	RNA polymerase activity
FNL83_RS08000	COG0194	GDP metabolic process
FNL83_RS08020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNL83_RS08025	COG0284	orotidine-5'-phosphate decarboxylase activity
FNL83_RS08030	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNL83_RS08035	COG0505	Belongs to the CarA family
FNL83_RS08040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNL83_RS08045	COG0540	Belongs to the ATCase OTCase family
FNL83_RS08050	COG2233	PERMEase
FNL83_RS08055	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FNL83_RS08060	COG0564	pseudouridine synthase activity
FNL83_RS08065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FNL83_RS08080	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FNL83_RS08085	COG3599	regulation of cell shape
FNL83_RS08095	COG0762	integral membrane protein
FNL83_RS08100	COG1799	cell septum assembly
FNL83_RS08105	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FNL83_RS08110	COG1496	oxidoreductase activity
FNL83_RS08115	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNL83_RS08120	COG0849	cell division
FNL83_RS08125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FNL83_RS08130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FNL83_RS08135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNL83_RS08140	COG0768	penicillin binding
FNL83_RS08145	COG4839	cell division protein FtsL
FNL83_RS08150	COG0275	rRNA processing
FNL83_RS08155	COG2001	Belongs to the MraZ family
FNL83_RS08160	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FNL83_RS08165	COG0454	-acetyltransferase
FNL83_RS08170	COG1011	Hydrolase
FNL83_RS08205	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FNL83_RS08210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNL83_RS08215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNL83_RS08220	COG1053	succinate dehydrogenase
FNL83_RS08225	COG2009	succinate dehydrogenase
FNL83_RS08235	COG0322	excinuclease ABC activity
FNL83_RS08240	COG3118	belongs to the thioredoxin family
FNL83_RS08245	COG1193	negative regulation of DNA recombination
FNL83_RS08250	COG1796	DNA polymerase
FNL83_RS08250	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FNL83_RS08260	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FNL83_RS08265	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNL83_RS08270	COG0072	phenylalanine-tRNA ligase activity
FNL83_RS08270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNL83_RS08275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNL83_RS08280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNL83_RS08295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FNL83_RS08310	COG1323	Belongs to the UPF0348 family
FNL83_RS08315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNL83_RS08320	COG0742	ribosomal rna small subunit methyltransferase
FNL83_RS08330	COG4471	UPF0298 protein
FNL83_RS08340	COG0584	glycerophosphoryl diester phosphodiesterase
FNL83_RS08345	COG3679	Belongs to the UPF0342 family
FNL83_RS08350	COG2340	Cysteine-rich secretory protein family
FNL83_RS08360	COG0109	protoheme IX farnesyltransferase activity
FNL83_RS08365	COG1612	heme a metabolic process
FNL83_RS08375	COG0772	Belongs to the SEDS family
FNL83_RS08380	COG4838	Belongs to the UPF0358 family
FNL83_RS08385	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNL83_RS08390	COG4896	Protein conserved in bacteria
FNL83_RS08405	COG1217	gtp-binding protein TYPA
FNL83_RS08415	COG0483	inositol monophosphate 1-phosphatase activity
FNL83_RS08420	COG4493	Belongs to the UPF0637 family
FNL83_RS08425	COG1914	H( )-stimulated, divalent metal cation uptake system
FNL83_RS08450	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNL83_RS08455	COG3842	ATPase activity
FNL83_RS08465	COG4476	Belongs to the UPF0223 family
FNL83_RS08475	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNL83_RS08480	COG0022	dehydrogenase e1 component
FNL83_RS08485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNL83_RS08495	COG0242	peptide deformylase activity
FNL83_RS08500	COG5503	Protein of unknown function (DUF1447)
FNL83_RS08505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FNL83_RS08510	COG0569	domain protein
FNL83_RS08515	COG1294	oxidase, subunit
FNL83_RS08520	COG1271	oxidase subunit
FNL83_RS08530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNL83_RS08535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNL83_RS08545	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FNL83_RS08560	COG4716	Myosin-crossreactive antigen
FNL83_RS08570	COG4172	Belongs to the ABC transporter superfamily
FNL83_RS08575	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FNL83_RS08580	COG0151	Belongs to the GarS family
FNL83_RS08585	COG0138	bifunctional purine biosynthesis protein purh
FNL83_RS08590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FNL83_RS08595	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNL83_RS08600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FNL83_RS08605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNL83_RS08610	COG0047	phosphoribosylformylglycinamidine synthase activity
FNL83_RS08615	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNL83_RS08620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNL83_RS08625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FNL83_RS08630	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FNL83_RS08635	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNL83_RS08645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FNL83_RS08650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNL83_RS08655	COG1845	cytochrome c oxidase, subunit III
FNL83_RS08660	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FNL83_RS08675	COG1316	TRANSCRIPTIONal
FNL83_RS08700	COG3594	Acyltransferase
FNL83_RS08705	COG0436	Aminotransferase
FNL83_RS08710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FNL83_RS08720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FNL83_RS08725	COG1169	isochorismate synthase
FNL83_RS08735	COG1575	Belongs to the MenA family. Type 1 subfamily
FNL83_RS08740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNL83_RS08750	COG2314	TM2 domain
FNL83_RS08825	COG4873	Protein conserved in bacteria
FNL83_RS08835	COG0737	Belongs to the 5'-nucleotidase family
FNL83_RS08840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FNL83_RS08845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNL83_RS08850	COG0861	Integral membrane protein TerC family
FNL83_RS08855	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FNL83_RS08865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNL83_RS08870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNL83_RS08875	COG2814	Major facilitator Superfamily
FNL83_RS08880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FNL83_RS08885	COG2382	esterase
FNL83_RS08890	COG0628	permease
FNL83_RS08920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNL83_RS08920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNL83_RS08930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNL83_RS08935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNL83_RS08940	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNL83_RS08945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNL83_RS08975	COG0475	glutathione-regulated potassium exporter activity
FNL83_RS08975	COG0569	domain protein
FNL83_RS08980	COG2239	Acts as a magnesium transporter
FNL83_RS08985	COG0564	pseudouridine synthase activity
FNL83_RS08990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNL83_RS08995	COG2357	RelA SpoT domain protein
FNL83_RS09010	COG2346	COG2346, Truncated hemoglobins
FNL83_RS09015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNL83_RS09020	COG1164	Oligoendopeptidase f
FNL83_RS09030	COG4862	establishment of competence for transformation
FNL83_RS09035	COG1393	Belongs to the ArsC family
FNL83_RS09040	COG0180	Tryptophanyl-tRNA synthetase
FNL83_RS09045	COG4166	transmembrane transport
FNL83_RS09050	COG4608	Belongs to the ABC transporter superfamily
FNL83_RS09055	COG0444	Belongs to the ABC transporter superfamily
FNL83_RS09060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNL83_RS09065	COG0601	transmembrane transport
FNL83_RS09080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNL83_RS09090	COG0542	response to heat
FNL83_RS09105	COG0561	phosphatase activity
FNL83_RS09110	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNL83_RS09120	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNL83_RS09125	COG1074	ATP-dependent DNA helicase activity
FNL83_RS09130	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FNL83_RS09145	COG0398	Pfam SNARE associated Golgi protein
FNL83_RS09150	COG0166	Belongs to the GPI family
FNL83_RS09155	COG0137	argininosuccinate synthase activity
FNL83_RS09160	COG0165	Argininosuccinate lyase
FNL83_RS09165	COG0584	glycerophosphoryl diester phosphodiesterase
FNL83_RS09175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNL83_RS09185	COG1902	pentaerythritol trinitrate reductase activity
FNL83_RS09190	COG1098	S1 RNA binding domain
FNL83_RS09195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNL83_RS09205	COG2111	Na H antiporter
FNL83_RS09205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNL83_RS09210	COG2111	Na H antiporter
FNL83_RS09215	COG1006	Multisubunit Na H antiporter MnhC subunit
FNL83_RS09220	COG0651	ATP synthesis coupled electron transport
FNL83_RS09225	COG1863	multisubunit Na H antiporter MnhE subunit
FNL83_RS09230	COG2212	antiporter activity
FNL83_RS09235	COG1320	monovalent cation:proton antiporter activity
FNL83_RS09245	COG2050	protein possibly involved in aromatic compounds catabolism
FNL83_RS09250	COG2056	Na+-H+ antiporter family
FNL83_RS09255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNL83_RS09265	COG1252	NADH dehydrogenase
FNL83_RS09270	COG0316	Belongs to the HesB IscA family
FNL83_RS09275	COG4844	belongs to the
FNL83_RS09280	COG1252	NADH dehydrogenase
FNL83_RS09285	COG4837	Protein of unknown function (DUF1462)
FNL83_RS09290	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FNL83_RS09295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FNL83_RS09300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNL83_RS09305	COG1696	Membrane protein involved in D-alanine export
FNL83_RS09310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNL83_RS09320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNL83_RS09325	COG0647	UMP catabolic process
FNL83_RS09330	COG2445	Protein of unknown function DUF86
FNL83_RS09340	COG4470	Protein conserved in bacteria
FNL83_RS09345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNL83_RS09350	COG0737	Belongs to the 5'-nucleotidase family
FNL83_RS09355	COG0730	response to heat
FNL83_RS09360	COG1801	Protein of unknown function DUF72
FNL83_RS09365	COG1253	flavin adenine dinucleotide binding
FNL83_RS09380	COG0719	Fe-S assembly protein
FNL83_RS09385	COG0822	iron-sulfur transferase activity
FNL83_RS09390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNL83_RS09395	COG0719	Fe-S assembly protein
FNL83_RS09400	COG0396	ATPase activity
FNL83_RS09410	COG3237	CsbD-like
FNL83_RS09420	COG1464	Belongs to the NlpA lipoprotein family
FNL83_RS09425	COG2011	ABC-type metal ion transport system permease component
FNL83_RS09430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNL83_RS09440	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FNL83_RS09450	COG0509	glycine decarboxylation via glycine cleavage system
FNL83_RS09455	COG1393	Belongs to the ArsC family
FNL83_RS09460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNL83_RS09470	COG0710	3-dehydroquinate dehydratase activity
FNL83_RS09475	COG1764	response to oxidative stress
FNL83_RS09530	COG4195	phage-related replication protein
FNL83_RS09545	COG1278	Cold shock
FNL83_RS09585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FNL83_RS09625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNL83_RS09630	COG0557	exoribonuclease II activity
FNL83_RS09635	COG1647	Serine aminopeptidase, S33
FNL83_RS09640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNL83_RS09650	COG0148	phosphopyruvate hydratase activity
FNL83_RS09655	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FNL83_RS09660	COG0149	triose-phosphate isomerase activity
FNL83_RS09665	COG0126	phosphoglycerate kinase activity
FNL83_RS09670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNL83_RS09690	COG1090	epimerase
FNL83_RS09700	COG0740	serine-type endopeptidase activity
FNL83_RS09710	COG1481	regulation of sporulation
FNL83_RS09715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FNL83_RS09720	COG1660	Displays ATPase and GTPase activities
FNL83_RS09725	COG0492	ferredoxin-NADP+ reductase activity
FNL83_RS09740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNL83_RS09745	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FNL83_RS09750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNL83_RS09755	COG0556	nucleotide-excision repair
FNL83_RS09775	COG3942	CHAP domain
FNL83_RS09775	COG1388	LysM domain
FNL83_RS09785	COG0653	protein targeting
FNL83_RS09790	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FNL83_RS09795	COG1040	competence protein
FNL83_RS09800	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FNL83_RS09810	COG1739	Uncharacterized protein family UPF0029
FNL83_RS09815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNL83_RS09820	COG2199	diguanylate cyclase activity
FNL83_RS09835	COG2195	Cleaves the N-terminal amino acid of tripeptides
FNL83_RS09840	COG1929	Belongs to the glycerate kinase type-1 family
FNL83_RS09860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FNL83_RS09875	COG4604	ABC transporter, ATP-binding protein
FNL83_RS09880	COG4605	iron ion homeostasis
FNL83_RS09885	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNL83_RS09895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNL83_RS09900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNL83_RS09905	COG1780	Probably involved in ribonucleotide reductase function
FNL83_RS09915	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FNL83_RS09920	COG3104	oligopeptide transport
FNL83_RS09925	COG1597	lipid kinase activity
FNL83_RS09930	COG1454	alcohol dehydrogenase
FNL83_RS09930	COG1012	belongs to the aldehyde dehydrogenase family
FNL83_RS09935	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
FNL83_RS09940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNL83_RS09945	COG1174	glycine betaine transport
FNL83_RS09955	COG0514	ATP-dependent DNA helicase (RecQ)
FNL83_RS09960	COG0488	(ABC) transporter
FNL83_RS09975	COG1368	sulfuric ester hydrolase activity
FNL83_RS09985	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNL83_RS10000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNL83_RS10010	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FNL83_RS10015	COG0720	synthase
FNL83_RS10020	COG0602	queuosine metabolic process
FNL83_RS10045	COG0745	RESPONSE REGULATOR receiver
FNL83_RS10050	COG5002	protein histidine kinase activity
FNL83_RS10055	COG0463	Glycosyl transferase, family 2
FNL83_RS10065	COG0656	L-ascorbic acid biosynthetic process
FNL83_RS10070	COG1253	flavin adenine dinucleotide binding
FNL83_RS10075	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FNL83_RS10080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNL83_RS10080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNL83_RS10080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNL83_RS10085	COG1105	Belongs to the carbohydrate kinase PfkB family
FNL83_RS10090	COG1349	DNA-binding transcription factor activity
FNL83_RS10100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNL83_RS10125	COG0415	Belongs to the DNA photolyase family
FNL83_RS10130	COG0471	metal ion transport
FNL83_RS10135	COG0039	L-malate dehydrogenase activity
FNL83_RS10160	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FNL83_RS10165	COG4988	ABC transporter
FNL83_RS10170	COG1968	undecaprenyl-diphosphatase activity
FNL83_RS10185	COG1671	Belongs to the UPF0178 family
FNL83_RS10190	COG1611	Belongs to the LOG family
FNL83_RS10215	COG2839	Protein conserved in bacteria
FNL83_RS10220	COG2814	Major facilitator Superfamily
FNL83_RS10225	COG0583	DNA-binding transcription factor activity
FNL83_RS10245	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FNL83_RS10255	COG0217	transcriptional regulatory protein
FNL83_RS10275	COG3942	CHAP domain
FNL83_RS10275	COG1388	LysM domain
FNL83_RS10280	COG0306	phosphate transporter
FNL83_RS10285	COG1392	Phosphate transport regulator
FNL83_RS10290	COG0577	efflux transmembrane transporter activity
FNL83_RS10295	COG1136	(ABC) transporter
FNL83_RS10300	COG2205	protein histidine kinase activity
FNL83_RS10305	COG0745	RESPONSE REGULATOR receiver
FNL83_RS10310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNL83_RS10325	COG3949	Membrane
FNL83_RS10335	COG1120	ATPase activity
FNL83_RS10340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNL83_RS10350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNL83_RS10355	COG1132	(ABC) transporter
FNL83_RS10370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FNL83_RS10380	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNL83_RS10385	COG1682	transport, permease protein
FNL83_RS10390	COG1134	teichoic acid transport
FNL83_RS10395	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FNL83_RS10405	COG1321	iron dependent repressor
FNL83_RS10410	COG1121	(ABC) transporter
FNL83_RS10415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNL83_RS10420	COG0803	Belongs to the bacterial solute-binding protein 9 family
FNL83_RS10430	COG1320	monovalent cation:proton antiporter activity
FNL83_RS10435	COG2212	antiporter activity
FNL83_RS10440	COG1863	multisubunit Na H antiporter MnhE subunit
FNL83_RS10445	COG0651	ATP synthesis coupled electron transport
FNL83_RS10450	COG1006	Multisubunit Na H antiporter MnhC subunit
FNL83_RS10455	COG2111	Na H antiporter
FNL83_RS10460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNL83_RS10460	COG2111	Na H antiporter
FNL83_RS10500	COG0596	Alpha beta hydrolase
FNL83_RS10520	COG0546	phosphoglycolate phosphatase activity
FNL83_RS10525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNL83_RS10530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNL83_RS10540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FNL83_RS10545	COG0018	arginyl-trna synthetase
FNL83_RS10570	COG1064	alcohol dehydrogenase
FNL83_RS10575	COG3875	lactate racemase activity
FNL83_RS10580	COG1606	tRNA processing
FNL83_RS10585	COG1691	(AIR) carboxylase
FNL83_RS10590	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FNL83_RS10600	COG1078	dGTPase activity
FNL83_RS10610	COG0667	Aldo Keto reductase
FNL83_RS10620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNL83_RS10625	COG4844	belongs to the
FNL83_RS10645	COG0095	Lipoate-protein ligase
FNL83_RS10650	COG0280	phosphate acetyltransferase
FNL83_RS10655	COG3253	May function as heme-dependent peroxidase
FNL83_RS10670	COG0531	amino acid
FNL83_RS10675	COG2363	Small membrane protein
FNL83_RS10685	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNL83_RS10695	COG0351	phosphomethylpyrimidine kinase
FNL83_RS10715	COG0183	Belongs to the thiolase family
FNL83_RS10720	COG0318	PFAM AMP-dependent synthetase and ligase
FNL83_RS10730	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNL83_RS10735	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FNL83_RS10740	COG0363	glucosamine-6-phosphate deaminase activity
FNL83_RS10750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNL83_RS10755	COG1469	GTP cyclohydrolase I activity
FNL83_RS10765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FNL83_RS10770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FNL83_RS10775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNL83_RS10790	COG0431	NADPH-dependent FMN reductase
FNL83_RS10795	COG0561	phosphatase activity
FNL83_RS10810	COG1428	Deoxynucleoside kinase
FNL83_RS10815	COG1428	Deoxynucleoside kinase
FNL83_RS10825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNL83_RS10830	COG0546	phosphoglycolate phosphatase activity
FNL83_RS10835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNL83_RS10840	COG1063	alcohol dehydrogenase
FNL83_RS10845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FNL83_RS10850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNL83_RS10855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNL83_RS10875	COG1473	amidohydrolase
FNL83_RS10880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNL83_RS10885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNL83_RS10895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FNL83_RS10905	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNL83_RS10910	COG0085	RNA polymerase activity
FNL83_RS10915	COG2813	Specifically methylates the guanine in position
FNL83_RS10920	COG0222	ribosome binding
FNL83_RS10925	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FNL83_RS10935	COG0081	regulation of translation
FNL83_RS10940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNL83_RS10945	COG0250	Participates in transcription elongation, termination and antitermination
FNL83_RS10950	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNL83_RS10955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNL83_RS10965	COG3688	RNA-binding protein containing a PIN domain
FNL83_RS10970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNL83_RS10975	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FNL83_RS10980	COG0215	cysteine-tRNA ligase activity
FNL83_RS10985	COG1045	serine acetyltransferase
FNL83_RS10990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNL83_RS10995	COG4956	integral membrane protein (PIN domain superfamily)
FNL83_RS11000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FNL83_RS11005	COG0542	response to heat
FNL83_RS11010	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FNL83_RS11015	COG3880	PFAM UvrB UvrC protein
FNL83_RS11020	COG4463	regulation of RNA biosynthetic process
FNL83_RS11025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNL83_RS11035	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNL83_RS11040	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FNL83_RS11045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNL83_RS11130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNL83_RS11135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FNL83_RS11140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNL83_RS11145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNL83_RS11150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNL83_RS11155	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FNL83_RS11160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNL83_RS11165	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FNL83_RS11170	COG0037	tRNA processing
FNL83_RS11175	COG1098	S1 RNA binding domain
FNL83_RS11185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FNL83_RS11190	COG3956	TIGRFAM MazG family protein
FNL83_RS11195	COG2244	polysaccharide biosynthetic process
FNL83_RS11200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FNL83_RS11205	COG0193	aminoacyl-tRNA hydrolase activity
FNL83_RS11210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FNL83_RS11215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNL83_RS11220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNL83_RS11225	COG2088	sporulation resulting in formation of a cellular spore
FNL83_RS11230	COG0251	oxidation-reduction process
FNL83_RS11235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNL83_RS11240	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FNL83_RS11245	COG4466	Protein conserved in bacteria
FNL83_RS11250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNL83_RS11255	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FNL83_RS11260	COG0084	hydrolase, TatD family'
FNL83_RS11265	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNL83_RS11265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNL83_RS11270	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FNL83_RS11275	COG2827	Endonuclease containing a URI domain
FNL83_RS11280	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FNL83_RS11285	COG4467	Involved in initiation control of chromosome replication
FNL83_RS11290	COG1774	PSP1 C-terminal conserved region
FNL83_RS11295	COG0470	DNA polymerase III
FNL83_RS11300	COG3870	Protein conserved in bacteria
FNL83_RS11305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FNL83_RS11310	COG1982	Orn Lys Arg decarboxylase major
FNL83_RS11335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNL83_RS11340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FNL83_RS11345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNL83_RS11365	COG2855	membrane
FNL83_RS11370	COG0583	DNA-binding transcription factor activity
FNL83_RS11380	COG0493	'glutamate synthase
FNL83_RS11385	COG0069	glutamate synthase activity
FNL83_RS11385	COG0070	glutamate synthase
FNL83_RS11385	COG0067	glutamate synthase
FNL83_RS11390	COG0583	DNA-binding transcription factor activity
FNL83_RS11420	COG0438	transferase activity, transferring glycosyl groups
FNL83_RS11425	COG3942	CHAP domain
FNL83_RS11425	COG1388	LysM domain
FNL83_RS11435	COG2011	ABC-type metal ion transport system permease component
FNL83_RS11440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNL83_RS11445	COG0626	cystathionine gamma-synthase activity
FNL83_RS11450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNL83_RS11460	COG0733	neurotransmitter:sodium symporter activity
FNL83_RS11470	COG1647	Serine aminopeptidase, S33
FNL83_RS11485	COG5609	conserved protein (DUF2294)
FNL83_RS11495	COG3002	Belongs to the UPF0753 family
FNL83_RS11500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNL83_RS11520	COG0523	cobalamin synthesis protein
FNL83_RS11575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNL83_RS11575	COG0519	Catalyzes the synthesis of GMP from XMP
FNL83_RS11580	COG0517	IMP dehydrogenase activity
FNL83_RS11580	COG0516	GMP reductase activity
FNL83_RS11585	COG2233	PERMEase
FNL83_RS11590	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNL83_RS11605	COG5183	chlorophyll binding
FNL83_RS11615	COG1823	symporter activity
FNL83_RS11620	COG0778	Nitroreductase
FNL83_RS11630	COG0450	alkyl hydroperoxide reductase
FNL83_RS11635	COG3634	alkyl hydroperoxide reductase activity
FNL83_RS11665	COG1280	lysine exporter protein (LysE YggA)
FNL83_RS11690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNL83_RS11700	COG0360	Binds together with S18 to 16S ribosomal RNA
FNL83_RS11715	COG0012	GTP binding
FNL83_RS11720	COG4481	Protein conserved in bacteria
FNL83_RS11725	COG0668	transmembrane transport
FNL83_RS11730	COG1475	DNA binding
FNL83_RS11740	COG0626	cystathionine gamma-synthase activity
FNL83_RS11745	COG0626	cystathionine gamma-synthase activity
FNL83_RS11750	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FNL83_RS11750	COG0646	methionine synthase
FNL83_RS11755	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FNL83_RS11765	COG0183	Belongs to the thiolase family
FNL83_RS11780	COG1476	TRANSCRIPTIONal
FNL83_RS11790	COG4555	ABC transporter
FNL83_RS11810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNL83_RS11855	COG1136	(ABC) transporter
FNL83_RS11860	COG0577	efflux transmembrane transporter activity
FNL83_RS11880	COG0577	efflux transmembrane transporter activity
FNL83_RS11885	COG1136	(ABC) transporter
FNL83_RS11925	COG1475	DNA binding
FNL83_RS11930	COG0357	Ribosomal RNA small subunit methyltransferase G
FNL83_RS11935	COG0445	tRNA wobble uridine modification
FNL83_RS11940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FNL83_RS11945	COG0594	ribonuclease P activity