locus-tag	class	description
JCQ37_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JCQ37_RS00010	COG0592	DNA-directed DNA polymerase activity
JCQ37_RS00015	COG2501	S4 domain
JCQ37_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JCQ37_RS00025	COG0187	DNA topoisomerase II activity
JCQ37_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JCQ37_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JCQ37_RS00040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JCQ37_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JCQ37_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JCQ37_RS00075	COG0359	binds to the 23S rRNA
JCQ37_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
JCQ37_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JCQ37_RS00100	COG0745	RESPONSE REGULATOR receiver
JCQ37_RS00105	COG5002	protein histidine kinase activity
JCQ37_RS00110	COG4863	YycH protein
JCQ37_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JCQ37_RS00125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JCQ37_RS00145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JCQ37_RS00145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JCQ37_RS00235	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JCQ37_RS00300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JCQ37_RS00305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JCQ37_RS00385	COG1611	Belongs to the LOG family
JCQ37_RS00395	COG0583	DNA-binding transcription factor activity
JCQ37_RS00465	COG4555	ABC transporter
JCQ37_RS00475	COG1476	TRANSCRIPTIONal
JCQ37_RS00490	COG0183	Belongs to the thiolase family
JCQ37_RS00500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JCQ37_RS00505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JCQ37_RS00505	COG0646	methionine synthase
JCQ37_RS00510	COG0626	cystathionine gamma-synthase activity
JCQ37_RS00515	COG0626	cystathionine gamma-synthase activity
JCQ37_RS00520	COG1475	DNA binding
JCQ37_RS00525	COG0668	transmembrane transport
JCQ37_RS00530	COG4481	Protein conserved in bacteria
JCQ37_RS00535	COG0012	GTP binding
JCQ37_RS00550	COG0360	Binds together with S18 to 16S ribosomal RNA
JCQ37_RS00560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JCQ37_RS00575	COG1280	lysine exporter protein (LysE YggA)
JCQ37_RS00580	COG0406	alpha-ribazole phosphatase activity
JCQ37_RS00600	COG3634	alkyl hydroperoxide reductase activity
JCQ37_RS00605	COG0450	alkyl hydroperoxide reductase
JCQ37_RS00615	COG0778	Nitroreductase
JCQ37_RS00620	COG1823	symporter activity
JCQ37_RS00625	COG5183	chlorophyll binding
JCQ37_RS00640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JCQ37_RS00645	COG2233	PERMEase
JCQ37_RS00650	COG0517	IMP dehydrogenase activity
JCQ37_RS00650	COG0516	GMP reductase activity
JCQ37_RS00655	COG0519	Catalyzes the synthesis of GMP from XMP
JCQ37_RS00655	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JCQ37_RS00700	COG0523	cobalamin synthesis protein
JCQ37_RS00720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JCQ37_RS00725	COG3002	Belongs to the UPF0753 family
JCQ37_RS00730	COG5609	conserved protein (DUF2294)
JCQ37_RS00745	COG1647	Serine aminopeptidase, S33
JCQ37_RS00755	COG0733	neurotransmitter:sodium symporter activity
JCQ37_RS00765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JCQ37_RS00770	COG0626	cystathionine gamma-synthase activity
JCQ37_RS00775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JCQ37_RS00780	COG2011	ABC-type metal ion transport system permease component
JCQ37_RS00790	COG3942	CHAP domain
JCQ37_RS00790	COG1388	LysM domain
JCQ37_RS00795	COG0438	transferase activity, transferring glycosyl groups
JCQ37_RS00820	COG0583	DNA-binding transcription factor activity
JCQ37_RS00825	COG0067	glutamate synthase
JCQ37_RS00825	COG0069	glutamate synthase activity
JCQ37_RS00825	COG0070	glutamate synthase
JCQ37_RS00830	COG0493	'glutamate synthase
JCQ37_RS00840	COG0583	DNA-binding transcription factor activity
JCQ37_RS00845	COG2855	membrane
JCQ37_RS00860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JCQ37_RS00865	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JCQ37_RS00870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JCQ37_RS00895	COG1982	Orn Lys Arg decarboxylase major
JCQ37_RS00900	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JCQ37_RS00905	COG3870	Protein conserved in bacteria
JCQ37_RS00910	COG0470	DNA polymerase III
JCQ37_RS00915	COG1774	PSP1 C-terminal conserved region
JCQ37_RS00920	COG4467	Involved in initiation control of chromosome replication
JCQ37_RS00925	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JCQ37_RS00930	COG2827	Endonuclease containing a URI domain
JCQ37_RS00935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JCQ37_RS00940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCQ37_RS00940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCQ37_RS00945	COG0084	hydrolase, TatD family'
JCQ37_RS00950	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JCQ37_RS00955	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JCQ37_RS00960	COG4466	Protein conserved in bacteria
JCQ37_RS00965	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JCQ37_RS00970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JCQ37_RS00975	COG0251	oxidation-reduction process
JCQ37_RS00980	COG2088	sporulation resulting in formation of a cellular spore
JCQ37_RS00985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JCQ37_RS00990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JCQ37_RS00995	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JCQ37_RS01000	COG0193	aminoacyl-tRNA hydrolase activity
JCQ37_RS01005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JCQ37_RS01010	COG2244	polysaccharide biosynthetic process
JCQ37_RS01015	COG3956	TIGRFAM MazG family protein
JCQ37_RS01020	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JCQ37_RS01030	COG1098	S1 RNA binding domain
JCQ37_RS01035	COG0037	tRNA processing
JCQ37_RS01040	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JCQ37_RS01045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JCQ37_RS01050	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JCQ37_RS01055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JCQ37_RS01060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JCQ37_RS01065	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JCQ37_RS01070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JCQ37_RS01075	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JCQ37_RS01160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCQ37_RS01165	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JCQ37_RS01170	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JCQ37_RS01180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JCQ37_RS01185	COG4463	regulation of RNA biosynthetic process
JCQ37_RS01190	COG3880	PFAM UvrB UvrC protein
JCQ37_RS01195	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JCQ37_RS01200	COG0542	response to heat
JCQ37_RS01205	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JCQ37_RS01210	COG4956	integral membrane protein (PIN domain superfamily)
JCQ37_RS01215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JCQ37_RS01220	COG1045	serine acetyltransferase
JCQ37_RS01225	COG0215	cysteine-tRNA ligase activity
JCQ37_RS01230	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JCQ37_RS01235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JCQ37_RS01240	COG3688	RNA-binding protein containing a PIN domain
JCQ37_RS01250	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JCQ37_RS01255	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JCQ37_RS01260	COG0250	Participates in transcription elongation, termination and antitermination
JCQ37_RS01265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JCQ37_RS01270	COG0081	regulation of translation
JCQ37_RS01275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JCQ37_RS01280	COG0222	ribosome binding
JCQ37_RS01285	COG2813	Specifically methylates the guanine in position
JCQ37_RS01290	COG0085	RNA polymerase activity
JCQ37_RS01295	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JCQ37_RS01305	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JCQ37_RS01315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JCQ37_RS01320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JCQ37_RS01325	COG1473	amidohydrolase
JCQ37_RS01345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JCQ37_RS01350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JCQ37_RS01355	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JCQ37_RS01360	COG1063	alcohol dehydrogenase
JCQ37_RS01365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ37_RS01370	COG0546	phosphoglycolate phosphatase activity
JCQ37_RS01375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCQ37_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ37_RS01385	COG1428	Deoxynucleoside kinase
JCQ37_RS01390	COG1428	Deoxynucleoside kinase
JCQ37_RS01400	COG0561	phosphatase activity
JCQ37_RS01405	COG0431	NADPH-dependent FMN reductase
JCQ37_RS01430	COG1469	GTP cyclohydrolase I activity
JCQ37_RS01435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JCQ37_RS01445	COG0363	glucosamine-6-phosphate deaminase activity
JCQ37_RS01450	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JCQ37_RS01455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JCQ37_RS01465	COG0318	PFAM AMP-dependent synthetase and ligase
JCQ37_RS01470	COG0183	Belongs to the thiolase family
JCQ37_RS01490	COG0351	phosphomethylpyrimidine kinase
JCQ37_RS01500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JCQ37_RS01510	COG2363	Small membrane protein
JCQ37_RS01515	COG0531	amino acid
JCQ37_RS01535	COG3253	May function as heme-dependent peroxidase
JCQ37_RS01540	COG0280	phosphate acetyltransferase
JCQ37_RS01545	COG0095	Lipoate-protein ligase
JCQ37_RS01565	COG4844	belongs to the
JCQ37_RS01570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JCQ37_RS01580	COG0667	Aldo Keto reductase
JCQ37_RS01590	COG1078	dGTPase activity
JCQ37_RS01600	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JCQ37_RS01605	COG1691	(AIR) carboxylase
JCQ37_RS01610	COG1606	tRNA processing
JCQ37_RS01615	COG3875	lactate racemase activity
JCQ37_RS01620	COG1064	alcohol dehydrogenase
JCQ37_RS01635	COG0018	arginyl-trna synthetase
JCQ37_RS01640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JCQ37_RS01650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JCQ37_RS01655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ37_RS01660	COG0546	phosphoglycolate phosphatase activity
JCQ37_RS01680	COG0596	Alpha beta hydrolase
JCQ37_RS01710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JCQ37_RS01710	COG2111	Na H antiporter
JCQ37_RS01715	COG2111	Na H antiporter
JCQ37_RS01720	COG1006	Multisubunit Na H antiporter MnhC subunit
JCQ37_RS01725	COG0651	ATP synthesis coupled electron transport
JCQ37_RS01730	COG1863	multisubunit Na H antiporter MnhE subunit
JCQ37_RS01735	COG2212	antiporter activity
JCQ37_RS01740	COG1320	monovalent cation:proton antiporter activity
JCQ37_RS01750	COG0803	Belongs to the bacterial solute-binding protein 9 family
JCQ37_RS01755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JCQ37_RS01760	COG1121	(ABC) transporter
JCQ37_RS01765	COG1321	iron dependent repressor
JCQ37_RS01775	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JCQ37_RS01780	COG1134	teichoic acid transport
JCQ37_RS01785	COG1682	transport, permease protein
JCQ37_RS01790	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ37_RS01800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JCQ37_RS01805	COG1132	(ABC) transporter
JCQ37_RS01810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JCQ37_RS01815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JCQ37_RS01820	COG1120	ATPase activity
JCQ37_RS01830	COG3949	Membrane
JCQ37_RS01845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JCQ37_RS01850	COG0745	RESPONSE REGULATOR receiver
JCQ37_RS01855	COG2205	protein histidine kinase activity
JCQ37_RS01860	COG1136	(ABC) transporter
JCQ37_RS01865	COG0577	efflux transmembrane transporter activity
JCQ37_RS01870	COG1392	Phosphate transport regulator
JCQ37_RS01875	COG0306	phosphate transporter
JCQ37_RS01880	COG3942	CHAP domain
JCQ37_RS01880	COG1388	LysM domain
JCQ37_RS01900	COG0217	transcriptional regulatory protein
JCQ37_RS01910	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
JCQ37_RS01930	COG0583	DNA-binding transcription factor activity
JCQ37_RS01935	COG2814	Major facilitator Superfamily
JCQ37_RS01940	COG2839	Protein conserved in bacteria
JCQ37_RS01965	COG1611	Belongs to the LOG family
JCQ37_RS01970	COG1671	Belongs to the UPF0178 family
JCQ37_RS01985	COG1968	undecaprenyl-diphosphatase activity
JCQ37_RS01990	COG4988	ABC transporter
JCQ37_RS01995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JCQ37_RS02015	COG0039	L-malate dehydrogenase activity
JCQ37_RS02020	COG0471	metal ion transport
JCQ37_RS02025	COG0415	Belongs to the DNA photolyase family
JCQ37_RS02050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JCQ37_RS02055	COG1349	DNA-binding transcription factor activity
JCQ37_RS02060	COG1105	Belongs to the carbohydrate kinase PfkB family
JCQ37_RS02065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JCQ37_RS02065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCQ37_RS02065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JCQ37_RS02070	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JCQ37_RS02075	COG1253	flavin adenine dinucleotide binding
JCQ37_RS02080	COG0656	L-ascorbic acid biosynthetic process
JCQ37_RS02085	COG0463	Glycosyl transferase, family 2
JCQ37_RS02090	COG5002	protein histidine kinase activity
JCQ37_RS02095	COG0745	RESPONSE REGULATOR receiver
JCQ37_RS02120	COG0602	queuosine metabolic process
JCQ37_RS02125	COG0720	synthase
JCQ37_RS02130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JCQ37_RS02140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JCQ37_RS02155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JCQ37_RS02165	COG1368	sulfuric ester hydrolase activity
JCQ37_RS02175	COG0488	(ABC) transporter
JCQ37_RS02180	COG0514	ATP-dependent DNA helicase (RecQ)
JCQ37_RS02190	COG1174	glycine betaine transport
JCQ37_RS02195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JCQ37_RS02200	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
JCQ37_RS02205	COG1454	alcohol dehydrogenase
JCQ37_RS02205	COG1012	belongs to the aldehyde dehydrogenase family
JCQ37_RS02210	COG1597	lipid kinase activity
JCQ37_RS02220	COG3104	oligopeptide transport
JCQ37_RS02225	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JCQ37_RS02235	COG1780	Probably involved in ribonucleotide reductase function
JCQ37_RS02240	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JCQ37_RS02245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JCQ37_RS02255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ37_RS02260	COG4605	iron ion homeostasis
JCQ37_RS02265	COG4604	ABC transporter, ATP-binding protein
JCQ37_RS02280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JCQ37_RS02300	COG1929	Belongs to the glycerate kinase type-1 family
JCQ37_RS02305	COG2195	Cleaves the N-terminal amino acid of tripeptides
JCQ37_RS02320	COG2199	diguanylate cyclase activity
JCQ37_RS02325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JCQ37_RS02330	COG1739	Uncharacterized protein family UPF0029
JCQ37_RS02340	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JCQ37_RS02345	COG1040	competence protein
JCQ37_RS02350	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JCQ37_RS02355	COG0653	protein targeting
JCQ37_RS02365	COG3942	CHAP domain
JCQ37_RS02365	COG1388	LysM domain
JCQ37_RS02380	COG0556	nucleotide-excision repair
JCQ37_RS02385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JCQ37_RS02390	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JCQ37_RS02395	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JCQ37_RS02410	COG0492	ferredoxin-NADP+ reductase activity
JCQ37_RS02415	COG1660	Displays ATPase and GTPase activities
JCQ37_RS02420	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JCQ37_RS02425	COG1481	regulation of sporulation
JCQ37_RS02435	COG0740	serine-type endopeptidase activity
JCQ37_RS02445	COG1090	epimerase
JCQ37_RS02465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JCQ37_RS02470	COG0126	phosphoglycerate kinase activity
JCQ37_RS02475	COG0149	triose-phosphate isomerase activity
JCQ37_RS02480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JCQ37_RS02485	COG0148	phosphopyruvate hydratase activity
JCQ37_RS02495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JCQ37_RS02500	COG1647	Serine aminopeptidase, S33
JCQ37_RS02505	COG0557	exoribonuclease II activity
JCQ37_RS02510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JCQ37_RS02550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JCQ37_RS02580	COG1278	Cold shock
JCQ37_RS02595	COG4195	phage-related replication protein
JCQ37_RS02640	COG1764	response to oxidative stress
JCQ37_RS02645	COG0710	3-dehydroquinate dehydratase activity
JCQ37_RS02655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JCQ37_RS02660	COG1393	Belongs to the ArsC family
JCQ37_RS02665	COG0509	glycine decarboxylation via glycine cleavage system
JCQ37_RS02670	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JCQ37_RS02680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JCQ37_RS02685	COG2011	ABC-type metal ion transport system permease component
JCQ37_RS02690	COG1464	Belongs to the NlpA lipoprotein family
JCQ37_RS02700	COG3237	CsbD-like
JCQ37_RS02710	COG0396	ATPase activity
JCQ37_RS02715	COG0719	Fe-S assembly protein
JCQ37_RS02720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JCQ37_RS02725	COG0822	iron-sulfur transferase activity
JCQ37_RS02730	COG0719	Fe-S assembly protein
JCQ37_RS02745	COG1253	flavin adenine dinucleotide binding
JCQ37_RS02750	COG1801	Protein of unknown function DUF72
JCQ37_RS02755	COG0730	response to heat
JCQ37_RS02760	COG0737	Belongs to the 5'-nucleotidase family
JCQ37_RS02765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JCQ37_RS02770	COG4470	Protein conserved in bacteria
JCQ37_RS02780	COG2445	Protein of unknown function DUF86
JCQ37_RS02785	COG0647	UMP catabolic process
JCQ37_RS02790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JCQ37_RS02800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JCQ37_RS02805	COG1696	Membrane protein involved in D-alanine export
JCQ37_RS02810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JCQ37_RS02815	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JCQ37_RS02820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JCQ37_RS02825	COG4837	Protein of unknown function (DUF1462)
JCQ37_RS02830	COG1252	NADH dehydrogenase
JCQ37_RS02835	COG4844	belongs to the
JCQ37_RS02840	COG0316	Belongs to the HesB IscA family
JCQ37_RS02845	COG1252	NADH dehydrogenase
JCQ37_RS02850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JCQ37_RS02855	COG2056	Na+-H+ antiporter family
JCQ37_RS02860	COG2050	protein possibly involved in aromatic compounds catabolism
JCQ37_RS02870	COG1320	monovalent cation:proton antiporter activity
JCQ37_RS02875	COG2212	antiporter activity
JCQ37_RS02880	COG1863	multisubunit Na H antiporter MnhE subunit
JCQ37_RS02885	COG0651	ATP synthesis coupled electron transport
JCQ37_RS02890	COG1006	Multisubunit Na H antiporter MnhC subunit
JCQ37_RS02895	COG2111	Na H antiporter
JCQ37_RS02900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JCQ37_RS02900	COG2111	Na H antiporter
JCQ37_RS02910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JCQ37_RS02915	COG1098	S1 RNA binding domain
JCQ37_RS02920	COG1902	pentaerythritol trinitrate reductase activity
JCQ37_RS02930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JCQ37_RS02940	COG0584	glycerophosphoryl diester phosphodiesterase
JCQ37_RS02945	COG0165	Argininosuccinate lyase
JCQ37_RS02950	COG0137	argininosuccinate synthase activity
JCQ37_RS02955	COG0166	Belongs to the GPI family
JCQ37_RS02960	COG0398	Pfam SNARE associated Golgi protein
JCQ37_RS02975	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JCQ37_RS02980	COG1074	ATP-dependent DNA helicase activity
JCQ37_RS02985	COG0179	Fumarylacetoacetate (FAA) hydrolase
JCQ37_RS03005	COG0446	pyridine nucleotide-disulphide oxidoreductase
JCQ37_RS03010	COG0561	phosphatase activity
JCQ37_RS03025	COG0542	response to heat
JCQ37_RS03040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JCQ37_RS03055	COG0601	transmembrane transport
JCQ37_RS03060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JCQ37_RS03065	COG0444	Belongs to the ABC transporter superfamily
JCQ37_RS03070	COG4608	Belongs to the ABC transporter superfamily
JCQ37_RS03075	COG4166	transmembrane transport
JCQ37_RS03080	COG0180	Tryptophanyl-tRNA synthetase
JCQ37_RS03085	COG1393	Belongs to the ArsC family
JCQ37_RS03095	COG4862	establishment of competence for transformation
JCQ37_RS03105	COG1164	Oligoendopeptidase f
JCQ37_RS03110	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JCQ37_RS03115	COG2346	COG2346, Truncated hemoglobins
JCQ37_RS03130	COG2357	RelA SpoT domain protein
JCQ37_RS03135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JCQ37_RS03140	COG0564	pseudouridine synthase activity
JCQ37_RS03145	COG2239	Acts as a magnesium transporter
JCQ37_RS03150	COG0475	glutathione-regulated potassium exporter activity
JCQ37_RS03150	COG0569	domain protein
JCQ37_RS03205	COG0628	permease
JCQ37_RS03210	COG2382	esterase
JCQ37_RS03215	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JCQ37_RS03220	COG2814	Major facilitator Superfamily
JCQ37_RS03225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JCQ37_RS03230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JCQ37_RS03240	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JCQ37_RS03245	COG0861	Integral membrane protein TerC family
JCQ37_RS03250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JCQ37_RS03255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JCQ37_RS03260	COG0737	Belongs to the 5'-nucleotidase family
JCQ37_RS03270	COG4873	Protein conserved in bacteria
JCQ37_RS03330	COG2314	TM2 domain
JCQ37_RS03335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JCQ37_RS03340	COG1575	Belongs to the MenA family. Type 1 subfamily
JCQ37_RS03345	COG1169	isochorismate synthase
JCQ37_RS03350	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JCQ37_RS03360	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JCQ37_RS03365	COG0436	Aminotransferase
JCQ37_RS03370	COG3594	Acyltransferase
JCQ37_RS03395	COG1316	TRANSCRIPTIONal
JCQ37_RS03410	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JCQ37_RS03415	COG1845	cytochrome c oxidase, subunit III
JCQ37_RS03420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JCQ37_RS03425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JCQ37_RS03435	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JCQ37_RS03440	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JCQ37_RS03445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JCQ37_RS03450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JCQ37_RS03455	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JCQ37_RS03460	COG0047	phosphoribosylformylglycinamidine synthase activity
JCQ37_RS03465	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JCQ37_RS03470	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JCQ37_RS03475	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JCQ37_RS03480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JCQ37_RS03485	COG0138	bifunctional purine biosynthesis protein purh
JCQ37_RS03490	COG0151	Belongs to the GarS family
JCQ37_RS03495	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JCQ37_RS03500	COG4172	Belongs to the ABC transporter superfamily
JCQ37_RS03510	COG4716	Myosin-crossreactive antigen
JCQ37_RS03525	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JCQ37_RS03535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JCQ37_RS03540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JCQ37_RS03550	COG1271	oxidase subunit
JCQ37_RS03555	COG1294	oxidase, subunit
JCQ37_RS03560	COG0569	domain protein
JCQ37_RS03565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JCQ37_RS03570	COG5503	Protein of unknown function (DUF1447)
JCQ37_RS03575	COG0242	peptide deformylase activity
JCQ37_RS03585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JCQ37_RS03590	COG0022	dehydrogenase e1 component
JCQ37_RS03595	COG0508	dehydrogenase complex catalyzes the overall conversion of
JCQ37_RS03605	COG4476	Belongs to the UPF0223 family
JCQ37_RS03615	COG3842	ATPase activity
JCQ37_RS03620	COG1176	ABC-type spermidine putrescine transport system, permease component I
JCQ37_RS03645	COG1914	H( )-stimulated, divalent metal cation uptake system
JCQ37_RS03650	COG4493	Belongs to the UPF0637 family
JCQ37_RS03655	COG0483	inositol monophosphate 1-phosphatase activity
JCQ37_RS03665	COG1217	gtp-binding protein TYPA
JCQ37_RS03675	COG4896	Protein conserved in bacteria
JCQ37_RS03680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JCQ37_RS03685	COG4838	Belongs to the UPF0358 family
JCQ37_RS03690	COG0772	Belongs to the SEDS family
JCQ37_RS03700	COG1612	heme a metabolic process
JCQ37_RS03705	COG0109	protoheme IX farnesyltransferase activity
JCQ37_RS03715	COG2340	Cysteine-rich secretory protein family
JCQ37_RS03720	COG3679	Belongs to the UPF0342 family
JCQ37_RS03725	COG0584	glycerophosphoryl diester phosphodiesterase
JCQ37_RS03730	COG4471	UPF0298 protein
JCQ37_RS03740	COG0742	ribosomal rna small subunit methyltransferase
JCQ37_RS03745	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JCQ37_RS03750	COG1323	Belongs to the UPF0348 family
JCQ37_RS03760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JCQ37_RS03770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JCQ37_RS03775	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JCQ37_RS03780	COG0072	phenylalanine-tRNA ligase activity
JCQ37_RS03780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCQ37_RS03785	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JCQ37_RS03790	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JCQ37_RS03800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JCQ37_RS03800	COG1796	DNA polymerase
JCQ37_RS03805	COG1193	negative regulation of DNA recombination
JCQ37_RS03810	COG3118	belongs to the thioredoxin family
JCQ37_RS03815	COG0322	excinuclease ABC activity
JCQ37_RS03820	COG2009	succinate dehydrogenase
JCQ37_RS03825	COG1053	succinate dehydrogenase
JCQ37_RS03830	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JCQ37_RS03835	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JCQ37_RS03840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JCQ37_RS03875	COG1011	Hydrolase
JCQ37_RS03880	COG0454	-acetyltransferase
JCQ37_RS03885	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JCQ37_RS03890	COG2001	Belongs to the MraZ family
JCQ37_RS03895	COG0275	rRNA processing
JCQ37_RS03900	COG4839	cell division protein FtsL
JCQ37_RS03905	COG0768	penicillin binding
JCQ37_RS03910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JCQ37_RS03915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JCQ37_RS03920	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JCQ37_RS03925	COG0849	cell division
JCQ37_RS03930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JCQ37_RS03935	COG1496	oxidoreductase activity
JCQ37_RS03940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JCQ37_RS03945	COG1799	cell septum assembly
JCQ37_RS03950	COG0762	integral membrane protein
JCQ37_RS03960	COG3599	regulation of cell shape
JCQ37_RS03965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JCQ37_RS03975	COG3942	CHAP domain
JCQ37_RS03975	COG1388	LysM domain
JCQ37_RS03980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JCQ37_RS03985	COG0564	pseudouridine synthase activity
JCQ37_RS03990	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JCQ37_RS03995	COG2233	PERMEase
JCQ37_RS04000	COG0540	Belongs to the ATCase OTCase family
JCQ37_RS04005	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JCQ37_RS04010	COG0505	Belongs to the CarA family
JCQ37_RS04015	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JCQ37_RS04020	COG0284	orotidine-5'-phosphate decarboxylase activity
JCQ37_RS04025	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JCQ37_RS04045	COG0194	GDP metabolic process
JCQ37_RS04050	COG1758	RNA polymerase activity
JCQ37_RS04055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JCQ37_RS04060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JCQ37_RS04070	COG0242	peptide deformylase activity
JCQ37_RS04075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JCQ37_RS04080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JCQ37_RS04080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JCQ37_RS04085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JCQ37_RS04090	COG0631	protein serine/threonine phosphatase activity
JCQ37_RS04100	COG1162	GTPase activity
JCQ37_RS04105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JCQ37_RS04115	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JCQ37_RS04120	COG1302	Protein conserved in bacteria
JCQ37_RS04125	COG1461	Dihydroxyacetone kinase
JCQ37_RS04130	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JCQ37_RS04135	COG1349	DNA-binding transcription factor activity
JCQ37_RS04140	COG0416	fatty acid biosynthetic process
JCQ37_RS04150	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ37_RS04155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JCQ37_RS04160	COG0571	ribonuclease III activity
JCQ37_RS04165	COG1196	nuclear chromosome segregation
JCQ37_RS04170	COG0552	protein localization to endoplasmic reticulum
JCQ37_RS04175	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JCQ37_RS04180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JCQ37_RS04185	COG0228	four-way junction DNA binding
JCQ37_RS04190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JCQ37_RS04195	COG0336	Belongs to the RNA methyltransferase TrmD family
JCQ37_RS04200	COG0335	large ribosomal subunit rRNA binding
JCQ37_RS04210	COG4485	Bacterial membrane protein, YfhO
JCQ37_RS04220	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JCQ37_RS04225	COG0045	succinate-CoA ligase (ADP-forming) activity
JCQ37_RS04230	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JCQ37_RS04235	COG0758	DNA mediated transformation
JCQ37_RS04240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JCQ37_RS04245	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JCQ37_RS04250	COG4974	Belongs to the 'phage' integrase family
JCQ37_RS04255	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JCQ37_RS04260	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JCQ37_RS04265	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JCQ37_RS04270	COG0052	Belongs to the universal ribosomal protein uS2 family
JCQ37_RS04275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JCQ37_RS04280	COG0528	UMP kinase activity
JCQ37_RS04285	COG0233	cytoplasmic translational termination
JCQ37_RS04290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JCQ37_RS04295	COG4589	Belongs to the CDS family
JCQ37_RS04305	COG0442	prolyl-tRNA aminoacylation
JCQ37_RS04310	COG2176	DNA-directed DNA polymerase activity
JCQ37_RS04315	COG0779	Required for maturation of 30S ribosomal subunits
JCQ37_RS04320	COG0195	Participates in both transcription termination and antitermination
JCQ37_RS04325	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JCQ37_RS04330	COG1358	cellular component organization or biogenesis
JCQ37_RS04335	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JCQ37_RS04340	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JCQ37_RS04345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JCQ37_RS04350	COG0196	riboflavin kinase activity
JCQ37_RS04355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JCQ37_RS04360	COG1185	polyribonucleotide nucleotidyltransferase activity
JCQ37_RS04365	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JCQ37_RS04370	COG1674	ftsk spoiiie
JCQ37_RS04375	COG2188	Transcriptional regulator
JCQ37_RS04380	COG0612	Peptidase, M16
JCQ37_RS04385	COG0612	Peptidase, M16
JCQ37_RS04390	COG0300	oxidoreductase activity
JCQ37_RS04405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JCQ37_RS04410	COG1546	Belongs to the CinA family
JCQ37_RS04410	COG1058	Belongs to the CinA family
JCQ37_RS04415	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JCQ37_RS04420	COG1418	mRNA catabolic process
JCQ37_RS04430	COG1692	metallophosphoesterase
JCQ37_RS04435	COG0674	pyruvate-flavodoxin oxidoreductase activity
JCQ37_RS04435	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JCQ37_RS04440	COG1013	pyruvate-flavodoxin oxidoreductase activity
JCQ37_RS04445	COG4195	phage-related replication protein
JCQ37_RS04455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JCQ37_RS04460	COG4550	Control of competence regulator ComK, YlbF/YmcA
JCQ37_RS04470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JCQ37_RS04475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JCQ37_RS04480	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JCQ37_RS04485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JCQ37_RS04490	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JCQ37_RS04495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JCQ37_RS04505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JCQ37_RS04510	COG1923	regulation of RNA biosynthetic process
JCQ37_RS04515	COG0386	Belongs to the glutathione peroxidase family
JCQ37_RS04520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JCQ37_RS04525	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JCQ37_RS04530	COG0789	Transcriptional regulator
JCQ37_RS04535	COG0174	glutamine synthetase
JCQ37_RS04575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JCQ37_RS04580	COG1131	(ABC) transporter
JCQ37_RS04590	COG4585	Histidine kinase
JCQ37_RS04595	COG2197	response regulator
JCQ37_RS04605	COG1525	nuclease
JCQ37_RS04620	COG0527	aspartate kinase activity
JCQ37_RS04625	COG0460	homoserine dehydrogenase
JCQ37_RS04630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JCQ37_RS04635	COG0083	homoserine kinase activity
JCQ37_RS04655	COG0833	amino acid
JCQ37_RS04660	COG0753	catalase activity
JCQ37_RS04670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JCQ37_RS04675	COG0516	GMP reductase activity
JCQ37_RS04680	COG2340	Cysteine-rich secretory protein family
JCQ37_RS04685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JCQ37_RS04695	COG4224	UPF0291 protein
JCQ37_RS04700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JCQ37_RS04710	COG4846	Membrane protein involved in cytochrome C biogenesis
JCQ37_RS04715	COG0420	3'-5' exonuclease activity
JCQ37_RS04720	COG0419	ATPase involved in DNA repair
JCQ37_RS04725	COG1970	mechanosensitive ion channel activity
JCQ37_RS04730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JCQ37_RS04735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JCQ37_RS04740	COG0824	Thioesterase
JCQ37_RS04745	COG4841	protein insertion into membrane
JCQ37_RS04750	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JCQ37_RS04755	COG0187	DNA topoisomerase II activity
JCQ37_RS04760	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JCQ37_RS04765	COG1115	amino acid carrier protein
JCQ37_RS04770	COG3711	transcriptional antiterminator
JCQ37_RS04775	COG0628	permease
JCQ37_RS04780	COG0392	lysyltransferase activity
JCQ37_RS04780	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JCQ37_RS04795	COG1942	4-Oxalocrotonate Tautomerase
JCQ37_RS04800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JCQ37_RS04805	COG0287	Prephenate dehydrogenase
JCQ37_RS04810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JCQ37_RS04815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JCQ37_RS04815	COG0512	Glutamine amidotransferase of anthranilate synthase
JCQ37_RS04820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JCQ37_RS04825	COG0134	indole-3-glycerol-phosphate synthase activity
JCQ37_RS04830	COG0135	phosphoribosylanthranilate isomerase activity
JCQ37_RS04835	COG0133	tryptophan synthase activity
JCQ37_RS04840	COG0159	tryptophan synthase activity
JCQ37_RS04850	COG2348	transferase activity, transferring amino-acyl groups
JCQ37_RS04855	COG2348	transferase activity, transferring amino-acyl groups
JCQ37_RS04865	COG4607	ABC-type enterochelin transport system periplasmic component
JCQ37_RS04900	COG0704	Plays a role in the regulation of phosphate uptake
JCQ37_RS04905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JCQ37_RS04910	COG0581	inorganic phosphate transmembrane transporter activity
JCQ37_RS04915	COG0573	inorganic phosphate transmembrane transporter activity
JCQ37_RS04920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JCQ37_RS04925	COG2996	Protein conserved in bacteria
JCQ37_RS04930	COG0488	(ABC) transporter
JCQ37_RS04935	COG0527	aspartate kinase activity
JCQ37_RS04940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JCQ37_RS04945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JCQ37_RS04950	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JCQ37_RS04955	COG2171	N-acyltransferase activity
JCQ37_RS04960	COG1473	amidohydrolase
JCQ37_RS04980	COG1131	(ABC) transporter
JCQ37_RS04995	COG1278	Cold shock
JCQ37_RS05005	COG1254	Belongs to the acylphosphatase family
JCQ37_RS05015	COG3853	Toxic anion resistance protein (TelA)
JCQ37_RS05020	COG1114	Component of the transport system for branched-chain amino acids
JCQ37_RS05025	COG4548	von Willebrand factor, type A
JCQ37_RS05030	COG0714	Associated with various cellular activities
JCQ37_RS05050	COG0508	dehydrogenase complex catalyzes the overall conversion of
JCQ37_RS05055	COG0567	Dehydrogenase, E1 component
JCQ37_RS05060	COG5002	protein histidine kinase activity
JCQ37_RS05065	COG0745	RESPONSE REGULATOR receiver
JCQ37_RS05075	COG0671	phosphoesterase, PA-phosphatase related
JCQ37_RS05080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JCQ37_RS05090	COG0793	Belongs to the peptidase S41A family
JCQ37_RS05095	COG4479	Belongs to the UPF0346 family
JCQ37_RS05100	COG2190	(PTS) system
JCQ37_RS05105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JCQ37_RS05130	COG1136	(ABC) transporter
JCQ37_RS05145	COG1413	lyase activity
JCQ37_RS05155	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JCQ37_RS05165	COG4372	Transposase
JCQ37_RS05165	COG1511	domain protein
JCQ37_RS05165	COG1196	nuclear chromosome segregation
JCQ37_RS05170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JCQ37_RS05175	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JCQ37_RS05185	COG0116	Belongs to the methyltransferase superfamily
JCQ37_RS05195	COG3599	regulation of cell shape
JCQ37_RS05200	COG4474	Belongs to the UPF0398 family
JCQ37_RS05210	COG3331	DNA recombination
JCQ37_RS05215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JCQ37_RS05215	COG4499	WXG100 protein secretion system (Wss), protein YukC
JCQ37_RS05225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JCQ37_RS05230	COG3935	DnaD domain protein
JCQ37_RS05235	COG0017	Asparaginyl-tRNA synthetase
JCQ37_RS05240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JCQ37_RS05240	COG1199	ATP-dependent helicase activity
JCQ37_RS05245	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JCQ37_RS05245	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JCQ37_RS05250	COG0617	tRNA 3'-terminal CCA addition
JCQ37_RS05255	COG0438	transferase activity, transferring glycosyl groups
JCQ37_RS05260	COG1694	Mazg nucleotide pyrophosphohydrolase
JCQ37_RS05265	COG2738	Putative neutral zinc metallopeptidase
JCQ37_RS05270	COG4347	Protein of unknown function (DUF1405)
JCQ37_RS05275	COG5582	Belongs to the UPF0302 family
JCQ37_RS05285	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JCQ37_RS05290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JCQ37_RS05295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JCQ37_RS05300	COG0105	UTP biosynthetic process
JCQ37_RS05310	COG2226	methyltransferase
JCQ37_RS05325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JCQ37_RS05330	COG1160	GTP binding
JCQ37_RS05335	COG0539	negative regulation of cytoplasmic translation
JCQ37_RS05340	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JCQ37_RS05345	COG0252	asparaginase activity
JCQ37_RS05350	COG0492	ferredoxin-NADP+ reductase activity
JCQ37_RS05355	COG1388	LysM domain
JCQ37_RS05360	COG0514	ATP-dependent DNA helicase (RecQ)
JCQ37_RS05370	COG1141	Ferredoxin
JCQ37_RS05385	COG0745	RESPONSE REGULATOR receiver
JCQ37_RS05390	COG1187	pseudouridine synthase activity
JCQ37_RS05395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JCQ37_RS05400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JCQ37_RS05405	COG1547	Domain of unknown function (DUF309)
JCQ37_RS05410	COG4974	Belongs to the 'phage' integrase family
JCQ37_RS05415	COG0735	belongs to the Fur family
JCQ37_RS05420	COG0494	nUDIX hydrolase
JCQ37_RS05425	COG0667	Aldo Keto reductase
JCQ37_RS05430	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ37_RS05435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JCQ37_RS05440	COG1234	tRNA 3'-trailer cleavage
JCQ37_RS05445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JCQ37_RS05455	COG0366	Alpha amylase catalytic
JCQ37_RS05460	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JCQ37_RS05465	COG2195	Cleaves the N-terminal amino acid of tripeptides
JCQ37_RS05475	COG4129	membrane
JCQ37_RS05485	COG0508	dehydrogenase complex catalyzes the overall conversion of
JCQ37_RS05490	COG0022	dehydrogenase e1 component
JCQ37_RS05495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JCQ37_RS05500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JCQ37_RS05505	COG0497	DNA recombination
JCQ37_RS05510	COG1438	arginine binding
JCQ37_RS05520	COG1722	exodeoxyribonuclease VII activity
JCQ37_RS05525	COG1570	exodeoxyribonuclease VII activity
JCQ37_RS05530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JCQ37_RS05535	COG1302	Protein conserved in bacteria
JCQ37_RS05540	COG0439	Biotin carboxylase
JCQ37_RS05545	COG0511	ligase activity, forming carbon-carbon bonds
JCQ37_RS05550	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JCQ37_RS05555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JCQ37_RS05560	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JCQ37_RS05565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JCQ37_RS05570	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JCQ37_RS05575	COG0006	proline dipeptidase activity
JCQ37_RS05590	COG0095	Lipoate-protein ligase
JCQ37_RS05595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JCQ37_RS05605	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JCQ37_RS05610	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JCQ37_RS05615	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JCQ37_RS05620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JCQ37_RS05640	COG4537	Required for transformation and DNA binding
JCQ37_RS05645	COG1459	type II secretion system
JCQ37_RS05650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JCQ37_RS05660	COG0011	TIGRFAM Protein of
JCQ37_RS05665	COG1940	carbohydrate kinase activity
JCQ37_RS05670	COG4483	Protein conserved in bacteria
JCQ37_RS05680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JCQ37_RS05685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JCQ37_RS05690	COG0768	penicillin binding
JCQ37_RS05695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JCQ37_RS05700	COG0735	belongs to the Fur family
JCQ37_RS05705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JCQ37_RS05710	COG1121	(ABC) transporter
JCQ37_RS05715	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JCQ37_RS05720	COG0513	Belongs to the DEAD box helicase family
JCQ37_RS05725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JCQ37_RS05730	COG2384	SAM-dependent methyltransferase
JCQ37_RS05735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JCQ37_RS05740	COG0358	DNA primase activity
JCQ37_RS05745	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JCQ37_RS05750	COG0517	IMP dehydrogenase activity
JCQ37_RS05755	COG0423	glycine-tRNA ligase activity
JCQ37_RS05760	COG1381	Involved in DNA repair and RecF pathway recombination
JCQ37_RS05765	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JCQ37_RS05770	COG0295	cytidine deaminase activity
JCQ37_RS05775	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JCQ37_RS05780	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JCQ37_RS05785	COG1702	phosphate starvation-inducible protein PhoH
JCQ37_RS05795	COG4864	UPF0365 protein
JCQ37_RS05800	COG1030	water channel activity
JCQ37_RS05810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JCQ37_RS05815	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JCQ37_RS05820	COG2264	protein methyltransferase activity
JCQ37_RS05825	COG0484	heat shock protein binding
JCQ37_RS05830	COG0443	Heat shock 70 kDa protein
JCQ37_RS05835	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JCQ37_RS05840	COG1420	regulation of RNA biosynthetic process
JCQ37_RS05845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JCQ37_RS05850	COG0481	GTPase activity
JCQ37_RS05855	COG0268	Binds directly to 16S ribosomal RNA
JCQ37_RS05860	COG1466	dna polymerase III delta subunit
JCQ37_RS05865	COG2333	competence protein COMEC
JCQ37_RS05865	COG0658	competence protein
JCQ37_RS05870	COG2131	deaminase
JCQ37_RS05880	COG2226	methyltransferase
JCQ37_RS05885	COG0799	negative regulation of ribosome biogenesis
JCQ37_RS05890	COG1713	HD superfamily hydrolase involved in NAD metabolism
JCQ37_RS05895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JCQ37_RS05900	COG1534	Rna-binding protein
JCQ37_RS05905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JCQ37_RS05910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JCQ37_RS05915	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JCQ37_RS05920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JCQ37_RS05925	COG1914	H( )-stimulated, divalent metal cation uptake system
JCQ37_RS05930	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JCQ37_RS05935	COG0439	Biotin carboxylase
JCQ37_RS05940	COG0511	ligase activity, forming carbon-carbon bonds
JCQ37_RS05945	COG1984	allophanate hydrolase subunit 2
JCQ37_RS05950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JCQ37_RS05960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JCQ37_RS05965	COG0572	uridine kinase
JCQ37_RS05970	COG0826	peptidase U32
JCQ37_RS05975	COG0826	peptidase U32
JCQ37_RS05985	COG3906	Belongs to the UPF0473 family
JCQ37_RS05990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JCQ37_RS05995	COG4472	Bacterial protein of unknown function (DUF965)
JCQ37_RS06000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JCQ37_RS06005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JCQ37_RS06015	COG0482	sulfurtransferase activity
JCQ37_RS06020	COG1104	cysteine desulfurase activity
JCQ37_RS06025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCQ37_RS06035	COG1959	2 iron, 2 sulfur cluster binding
JCQ37_RS06040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JCQ37_RS06045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JCQ37_RS06055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JCQ37_RS06060	COG0124	histidyl-tRNA synthetase
JCQ37_RS06065	COG0860	N-Acetylmuramoyl-L-alanine amidase
JCQ37_RS06070	COG1490	D-aminoacyl-tRNA deacylase activity
JCQ37_RS06075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JCQ37_RS06080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JCQ37_RS06085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JCQ37_RS06085	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JCQ37_RS06090	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JCQ37_RS06090	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JCQ37_RS06095	COG1862	Preprotein translocase
JCQ37_RS06100	COG0343	queuine tRNA-ribosyltransferase activity
JCQ37_RS06105	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JCQ37_RS06110	COG2255	four-way junction helicase activity
JCQ37_RS06115	COG0632	four-way junction helicase activity
JCQ37_RS06120	COG4492	Belongs to the UPF0735 family
JCQ37_RS06125	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JCQ37_RS06130	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JCQ37_RS06135	COG2868	ribosomal protein
JCQ37_RS06140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JCQ37_RS06170	COG2003	Belongs to the UPF0758 family
JCQ37_RS06180	COG0285	dihydrofolate synthase activity
JCQ37_RS06185	COG0525	valine-tRNA ligase activity
JCQ37_RS06190	COG2818	Glycosylase
JCQ37_RS06200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JCQ37_RS06205	COG0113	porphobilinogen synthase activity
JCQ37_RS06215	COG0181	hydroxymethylbilane synthase activity
JCQ37_RS06225	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JCQ37_RS06230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JCQ37_RS06235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JCQ37_RS06240	COG0544	peptidyl-prolyl cis-trans isomerase activity
JCQ37_RS06250	COG4112	unkown
JCQ37_RS06255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JCQ37_RS06260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JCQ37_RS06265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JCQ37_RS06270	COG0833	amino acid
JCQ37_RS06275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JCQ37_RS06280	COG1484	DNA-dependent DNA replication
JCQ37_RS06285	COG3611	Membrane attachment protein
JCQ37_RS06290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JCQ37_RS06300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JCQ37_RS06310	COG0237	dephospho-CoA kinase activity
JCQ37_RS06315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JCQ37_RS06320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JCQ37_RS06320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JCQ37_RS06325	COG5002	protein histidine kinase activity
JCQ37_RS06330	COG0745	RESPONSE REGULATOR receiver
JCQ37_RS06335	COG0538	isocitrate dehydrogenase activity
JCQ37_RS06340	COG0372	Belongs to the citrate synthase family
JCQ37_RS06345	COG1113	amino acid transport
JCQ37_RS06350	COG0469	pyruvate kinase activity
JCQ37_RS06355	COG0205	6-phosphofructokinase activity
JCQ37_RS06360	COG0825	malonyl-CoA metabolic process
JCQ37_RS06365	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JCQ37_RS06370	COG0281	malic enzyme
JCQ37_RS06375	COG0587	DNA-directed DNA polymerase activity
JCQ37_RS06380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JCQ37_RS06385	COG4109	DRTGG domain
JCQ37_RS06395	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JCQ37_RS06400	COG0006	proline dipeptidase activity
JCQ37_RS06405	COG0686	Belongs to the AlaDH PNT family
JCQ37_RS06410	COG0589	response to stress
JCQ37_RS06420	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JCQ37_RS06425	COG0827	DNA restriction-modification system
JCQ37_RS06430	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JCQ37_RS06440	COG0301	tRNA thio-modification
JCQ37_RS06450	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JCQ37_RS06455	COG1956	GAF domain-containing protein
JCQ37_RS06460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JCQ37_RS06465	COG0584	glycerophosphoryl diester phosphodiesterase
JCQ37_RS06470	COG1764	response to oxidative stress
JCQ37_RS06475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JCQ37_RS06480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JCQ37_RS06490	COG1263	PTS System
JCQ37_RS06490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ37_RS06495	COG0204	Acyl-transferase
JCQ37_RS06500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JCQ37_RS06505	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JCQ37_RS06515	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JCQ37_RS06520	COG1609	Transcriptional regulator
JCQ37_RS06525	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JCQ37_RS06525	COG1605	Chorismate mutase
JCQ37_RS06535	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JCQ37_RS06540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JCQ37_RS06545	COG1674	ftsk spoiiie
JCQ37_RS06550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCQ37_RS06555	COG4848	Belongs to the UPF0354 family
JCQ37_RS06560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JCQ37_RS06565	COG1363	Peptidase, m42
JCQ37_RS06575	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JCQ37_RS06580	COG0510	thiamine kinase activity
JCQ37_RS06585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JCQ37_RS06590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JCQ37_RS06600	COG1187	pseudouridine synthase activity
JCQ37_RS06605	COG2244	polysaccharide biosynthetic process
JCQ37_RS06610	COG2081	HI0933 family
JCQ37_RS06625	COG0495	leucyl-tRNA aminoacylation
JCQ37_RS06630	COG2814	Major facilitator Superfamily
JCQ37_RS06635	COG1242	4 iron, 4 sulfur cluster binding
JCQ37_RS06640	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JCQ37_RS06650	COG2267	carboxylic ester hydrolase activity
JCQ37_RS06655	COG0506	proline dehydrogenase activity
JCQ37_RS06660	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JCQ37_RS06665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JCQ37_RS06665	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JCQ37_RS06675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JCQ37_RS06675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JCQ37_RS06685	COG5632	N-Acetylmuramoyl-L-alanine amidase
JCQ37_RS06685	COG4193	domain, Protein
JCQ37_RS06685	COG3266	domain, Protein
JCQ37_RS06710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JCQ37_RS06720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JCQ37_RS06725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JCQ37_RS06735	COG0656	L-ascorbic acid biosynthetic process
JCQ37_RS06745	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JCQ37_RS06750	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JCQ37_RS06755	COG1506	peptidase
JCQ37_RS06760	COG0494	nUDIX hydrolase
JCQ37_RS06765	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JCQ37_RS06775	COG0318	PFAM AMP-dependent synthetase and ligase
JCQ37_RS06850	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JCQ37_RS06855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JCQ37_RS06860	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JCQ37_RS06865	COG2329	Antibiotic biosynthesis monooxygenase
JCQ37_RS06875	COG4473	ABC transporter
JCQ37_RS06880	COG1131	(ABC) transporter
JCQ37_RS06885	COG0537	adenosine 5'-monophosphoramidase activity
JCQ37_RS06900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JCQ37_RS06910	COG3481	metal-dependent phosphohydrolase, HD sub domain
JCQ37_RS06920	COG0420	3'-5' exonuclease activity
JCQ37_RS06925	COG3679	Belongs to the UPF0342 family
JCQ37_RS06930	COG4399	Belongs to the UPF0754 family
JCQ37_RS06940	COG2197	response regulator
JCQ37_RS06945	COG4585	Histidine kinase
JCQ37_RS06945	COG2203	Gaf domain
JCQ37_RS06950	COG0564	pseudouridine synthase activity
JCQ37_RS06955	COG0114	fumarate hydratase activity
JCQ37_RS06980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JCQ37_RS06990	COG1126	abc transporter atp-binding protein
JCQ37_RS06995	COG0765	amino acid transport
JCQ37_RS07165	COG0735	belongs to the Fur family
JCQ37_RS07170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JCQ37_RS07175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JCQ37_RS07180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JCQ37_RS07185	COG4129	membrane
JCQ37_RS07195	COG3557	Belongs to the UPF0374 family
JCQ37_RS07205	COG1988	membrane-bound metal-dependent
JCQ37_RS07215	COG1134	teichoic acid transport
JCQ37_RS07215	COG1388	LysM domain
JCQ37_RS07225	COG2137	regulation of response to DNA damage stimulus
JCQ37_RS07230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JCQ37_RS07235	COG0693	protein deglycase activity
JCQ37_RS07245	COG0535	radical SAM domain protein
JCQ37_RS07250	COG1607	acyl-coa hydrolase
JCQ37_RS07255	COG2309	aminopeptidase activity
JCQ37_RS07260	COG4840	Belongs to the UPF0435 family
JCQ37_RS07265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JCQ37_RS07275	COG1295	ribonuclease BN
JCQ37_RS07280	COG2197	response regulator
JCQ37_RS07285	COG4585	Histidine kinase
JCQ37_RS07300	COG0024	Methionine aminopeptidase
JCQ37_RS07305	COG4129	membrane
JCQ37_RS07325	COG1528	Iron-storage protein
JCQ37_RS07335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JCQ37_RS07345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JCQ37_RS07350	COG1597	lipid kinase activity
JCQ37_RS07355	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JCQ37_RS07360	COG0154	amidase activity
JCQ37_RS07365	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JCQ37_RS07370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JCQ37_RS07375	COG4851	CamS sex pheromone cAM373 precursor
JCQ37_RS07380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JCQ37_RS07385	COG0210	DNA helicase
JCQ37_RS07390	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JCQ37_RS07395	COG4496	protein, YerC YecD
JCQ37_RS07400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JCQ37_RS07410	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JCQ37_RS07415	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JCQ37_RS07420	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JCQ37_RS07430	COG0077	Prephenate dehydratase
JCQ37_RS07440	COG1335	isochorismatase
JCQ37_RS07445	COG1227	inorganic diphosphatase activity
JCQ37_RS07450	COG1012	belongs to the aldehyde dehydrogenase family
JCQ37_RS07455	COG2706	6-phosphogluconolactonase activity
JCQ37_RS07500	COG1131	(ABC) transporter
JCQ37_RS07510	COG1131	(ABC) transporter
JCQ37_RS07515	COG1725	Transcriptional regulator
JCQ37_RS07565	COG3728	DNA packaging
JCQ37_RS07565	COG5484	DNA packaging
JCQ37_RS07640	COG1396	sequence-specific DNA binding
JCQ37_RS07645	COG0582	viral genome integration into host DNA
JCQ37_RS07650	COG0459	protein refolding
JCQ37_RS07655	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JCQ37_RS07690	COG3290	protein histidine kinase activity
JCQ37_RS07695	COG3279	Response regulator of the LytR AlgR family
JCQ37_RS07700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JCQ37_RS07705	COG1621	beta-fructofuranosidase activity
JCQ37_RS07710	COG1609	Transcriptional regulator
JCQ37_RS07715	COG0004	ammonium transporteR
JCQ37_RS07720	COG0425	Belongs to the sulfur carrier protein TusA family
JCQ37_RS07725	COG2391	methyltransferase activity
JCQ37_RS07735	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JCQ37_RS07740	COG0488	(ABC) transporter
JCQ37_RS07745	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JCQ37_RS07750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JCQ37_RS07755	COG0456	acetyltransferase
JCQ37_RS07760	COG1214	PFAM Peptidase M22, glycoprotease
JCQ37_RS07765	COG0802	atpase or kinase
JCQ37_RS07770	COG0129	dihydroxy-acid dehydratase activity
JCQ37_RS07775	COG0028	Belongs to the TPP enzyme family
JCQ37_RS07785	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JCQ37_RS07790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JCQ37_RS07795	COG0473	3-isopropylmalate dehydrogenase activity
JCQ37_RS07800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JCQ37_RS07805	COG0066	3-isopropylmalate dehydratase activity
JCQ37_RS07810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JCQ37_RS07840	COG3091	SprT-like family
JCQ37_RS07845	COG2183	response to ionizing radiation
JCQ37_RS07850	COG1191	sigma factor activity
JCQ37_RS07865	COG2208	phosphoserine phosphatase activity
JCQ37_RS07870	COG2337	Toxic component of a toxin-antitoxin (TA) module
JCQ37_RS07880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JCQ37_RS07885	COG0736	holo-[acyl-carrier-protein] synthase activity
JCQ37_RS07890	COG3402	PFAM membrane-flanked domain
JCQ37_RS07895	COG3428	Bacterial PH domain
JCQ37_RS07905	COG0513	Belongs to the DEAD box helicase family
JCQ37_RS07910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JCQ37_RS07915	COG1181	Belongs to the D-alanine--D-alanine ligase family
JCQ37_RS07920	COG0772	Belongs to the SEDS family
JCQ37_RS07935	COG1937	Protein conserved in bacteria
JCQ37_RS07940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JCQ37_RS07945	COG1418	mRNA catabolic process
JCQ37_RS07950	COG0706	membrane insertase activity
JCQ37_RS07955	COG0352	thiamine-phosphate diphosphorylase activity
JCQ37_RS07960	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JCQ37_RS07970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JCQ37_RS07975	COG1388	LysM domain
JCQ37_RS07980	COG0629	single-stranded DNA binding
JCQ37_RS07990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JCQ37_RS07995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JCQ37_RS08005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JCQ37_RS08010	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JCQ37_RS08015	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JCQ37_RS08020	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JCQ37_RS08025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JCQ37_RS08030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JCQ37_RS08040	COG0356	it plays a direct role in the translocation of protons across the membrane
JCQ37_RS08050	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JCQ37_RS08055	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JCQ37_RS08060	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JCQ37_RS08065	COG4475	Protein of unknown function (DUF436)
JCQ37_RS08070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JCQ37_RS08075	COG0009	L-threonylcarbamoyladenylate synthase
JCQ37_RS08080	COG2890	protein-(glutamine-N5) methyltransferase activity
JCQ37_RS08085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JCQ37_RS08090	COG1435	thymidine kinase activity
JCQ37_RS08095	COG0254	rRNA binding
JCQ37_RS08100	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JCQ37_RS08105	COG1012	belongs to the aldehyde dehydrogenase family
JCQ37_RS08110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JCQ37_RS08115	COG0191	fructose-bisphosphate aldolase activity
JCQ37_RS08125	COG0504	CTP synthase activity
JCQ37_RS08130	COG3343	RNA polymerase activity
JCQ37_RS08140	COG5146	pantothenate kinase activity
JCQ37_RS08160	COG1854	S-ribosylhomocysteine lyase activity
JCQ37_RS08170	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JCQ37_RS08175	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JCQ37_RS08180	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JCQ37_RS08185	COG0813	purine-nucleoside phosphorylase activity
JCQ37_RS08190	COG0783	Belongs to the Dps family
JCQ37_RS08210	COG1482	cell wall glycoprotein biosynthetic process
JCQ37_RS08215	COG0702	epimerase
JCQ37_RS08220	COG0640	Transcriptional regulator
JCQ37_RS08240	COG0561	phosphatase activity
JCQ37_RS08245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JCQ37_RS08250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JCQ37_RS08260	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JCQ37_RS08310	COG0489	protein tyrosine kinase activity
JCQ37_RS08315	COG2814	Major facilitator Superfamily
JCQ37_RS08335	COG4284	Utp--glucose-1-phosphate uridylyltransferase
JCQ37_RS08340	COG1988	membrane-bound metal-dependent
JCQ37_RS08350	COG2329	Antibiotic biosynthesis monooxygenase
JCQ37_RS08355	COG3314	Sporulation integral membrane protein YlbJ
JCQ37_RS08360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ37_RS08365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCQ37_RS08370	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JCQ37_RS08375	COG3457	Alanine racemase
JCQ37_RS08380	COG4264	IucA IucC family
JCQ37_RS08385	COG2814	Major facilitator Superfamily
JCQ37_RS08390	COG4264	IucA IucC family
JCQ37_RS08395	COG1302	Protein conserved in bacteria
JCQ37_RS08410	COG0604	alcohol dehydrogenase
JCQ37_RS08415	COG2130	NADP-dependent
JCQ37_RS08420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCQ37_RS08430	COG2723	6-phospho-beta-galactosidase activity
JCQ37_RS08435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JCQ37_RS08435	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JCQ37_RS08440	COG1447	Phosphotransferase system cellobiose-specific component IIA
JCQ37_RS08445	COG3684	Belongs to the aldolase LacD family
JCQ37_RS08450	COG1105	Belongs to the carbohydrate kinase PfkB family
JCQ37_RS08455	COG0698	ribose 5-phosphate isomerase
JCQ37_RS08460	COG0698	ribose 5-phosphate isomerase
JCQ37_RS08465	COG1349	DNA-binding transcription factor activity
JCQ37_RS08470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JCQ37_RS08475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JCQ37_RS08480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JCQ37_RS08485	COG0101	tRNA pseudouridine synthase activity
JCQ37_RS08495	COG1122	ATPase activity
JCQ37_RS08500	COG1122	ATPase activity
JCQ37_RS08505	COG0203	ribosomal protein L17
JCQ37_RS08510	COG0202	RNA polymerase activity
JCQ37_RS08515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JCQ37_RS08520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JCQ37_RS08525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JCQ37_RS08530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JCQ37_RS08535	COG0563	adenylate kinase activity
JCQ37_RS08540	COG0201	protein transport
JCQ37_RS08545	COG0200	Binds to the 23S rRNA
JCQ37_RS08550	COG1841	ribosomal large subunit assembly
JCQ37_RS08555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JCQ37_RS08560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JCQ37_RS08565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JCQ37_RS08570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JCQ37_RS08575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JCQ37_RS08580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JCQ37_RS08585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JCQ37_RS08590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JCQ37_RS08595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JCQ37_RS08605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JCQ37_RS08610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JCQ37_RS08615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JCQ37_RS08620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JCQ37_RS08625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JCQ37_RS08630	COG0089	rRNA binding
JCQ37_RS08635	COG0088	Forms part of the polypeptide exit tunnel
JCQ37_RS08640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JCQ37_RS08655	COG2252	PERMEase
JCQ37_RS08660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JCQ37_RS08660	COG0551	DNA topoisomerase type I activity
JCQ37_RS08665	COG4975	Glucose uptake
JCQ37_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ37_RS08690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JCQ37_RS08695	COG2348	transferase activity, transferring amino-acyl groups
JCQ37_RS08730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JCQ37_RS08735	COG0746	molybdenum cofactor guanylyltransferase activity
JCQ37_RS08745	COG0314	molybdopterin synthase activity
JCQ37_RS08755	COG0303	'Molybdopterin
JCQ37_RS08760	COG0315	cyclic pyranopterin monophosphate synthase activity
JCQ37_RS08765	COG0521	Mo-molybdopterin cofactor biosynthetic process
JCQ37_RS08770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JCQ37_RS08775	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JCQ37_RS08780	COG4149	molybdate abc transporter
JCQ37_RS08785	COG0725	ABC transporter, periplasmic molybdate-binding protein
JCQ37_RS08800	COG1268	BioY protein
JCQ37_RS08805	COG1957	nucleoside hydrolase
JCQ37_RS08810	COG1960	acyl-CoA dehydrogenase activity
JCQ37_RS08820	COG0831	urea catabolic process
JCQ37_RS08825	COG0832	Belongs to the urease beta subunit family
JCQ37_RS08830	COG0804	urea catabolic process
JCQ37_RS08835	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
JCQ37_RS08840	COG0830	nickel cation binding
JCQ37_RS08845	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JCQ37_RS08850	COG0829	nickel cation binding
JCQ37_RS08875	COG3942	CHAP domain
JCQ37_RS08880	COG1757	Na H antiporter
JCQ37_RS08895	COG3942	CHAP domain
JCQ37_RS08900	COG2076	Multidrug Resistance protein
JCQ37_RS08905	COG2076	Multidrug Resistance protein
JCQ37_RS08910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JCQ37_RS08930	COG1316	TRANSCRIPTIONal
JCQ37_RS08935	COG0483	inositol monophosphate 1-phosphatase activity
JCQ37_RS08940	COG2378	regulation of single-species biofilm formation
JCQ37_RS08945	COG1266	CAAX protease self-immunity
JCQ37_RS08960	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JCQ37_RS08965	COG1263	PTS System
JCQ37_RS08965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ37_RS08975	COG1113	amino acid transport
JCQ37_RS08995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JCQ37_RS09005	COG1263	PTS System
JCQ37_RS09005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ37_RS09010	COG1737	Transcriptional regulator
JCQ37_RS09035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JCQ37_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ37_RS09045	COG1473	amidohydrolase
JCQ37_RS09050	COG0010	Belongs to the arginase family
JCQ37_RS09055	COG1266	CAAX protease self-immunity
JCQ37_RS09065	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JCQ37_RS09070	COG2258	MOSC domain
JCQ37_RS09075	COG2017	converts alpha-aldose to the beta-anomer
JCQ37_RS09080	COG1069	ribulokinase activity
JCQ37_RS09090	COG2094	Belongs to the DNA glycosylase MPG family
JCQ37_RS09110	COG0786	glutamate:sodium symporter activity
JCQ37_RS09115	COG1304	FMN binding
JCQ37_RS09120	COG0598	Magnesium transport protein CorA
JCQ37_RS09135	COG0657	acetylesterase activity
JCQ37_RS09145	COG2814	Major facilitator Superfamily
JCQ37_RS09150	COG1566	PFAM secretion protein HlyD family protein
JCQ37_RS09160	COG2814	Major facilitator Superfamily
JCQ37_RS09165	COG4640	response to antibiotic
JCQ37_RS09185	COG1136	(ABC) transporter
JCQ37_RS09190	COG0577	efflux transmembrane transporter activity
JCQ37_RS09195	COG0745	RESPONSE REGULATOR receiver
JCQ37_RS09200	COG3850	Histidine kinase
JCQ37_RS09200	COG5002	protein histidine kinase activity
JCQ37_RS09205	COG0579	oxidoreductase
JCQ37_RS09210	COG0438	transferase activity, transferring glycosyl groups
JCQ37_RS09215	COG1620	l-lactate permease
JCQ37_RS09220	COG0463	Glycosyl transferase, family 2
JCQ37_RS09220	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ37_RS09230	COG0463	Glycosyl transferase, family 2
JCQ37_RS09230	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ37_RS09235	COG0456	acetyltransferase
JCQ37_RS09240	COG0604	alcohol dehydrogenase
JCQ37_RS09275	COG1263	PTS System
JCQ37_RS09275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ37_RS09290	COG3871	stress protein (general stress protein 26)
JCQ37_RS09310	COG0778	Nitroreductase
JCQ37_RS09315	COG1846	Transcriptional regulator
JCQ37_RS09320	COG2223	nitrite transmembrane transporter activity
JCQ37_RS09325	COG2197	response regulator
JCQ37_RS09330	COG4585	Histidine kinase
JCQ37_RS09340	COG2181	nitrate reductase activity
JCQ37_RS09350	COG1140	nitrate reductase beta subunit
JCQ37_RS09355	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JCQ37_RS09365	COG2146	nitrite reductase [NAD(P)H] activity
JCQ37_RS09370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JCQ37_RS09380	COG0747	negative chemotaxis
JCQ37_RS09395	COG2116	formate transmembrane transporter activity
JCQ37_RS09415	COG2348	transferase activity, transferring amino-acyl groups
JCQ37_RS09425	COG1126	abc transporter atp-binding protein
JCQ37_RS09430	COG0765	amino acid transport
JCQ37_RS09435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JCQ37_RS09445	COG0588	phosphoglycerate mutase activity
JCQ37_RS09450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JCQ37_RS09465	COG1929	Belongs to the glycerate kinase type-1 family
JCQ37_RS09490	COG1113	amino acid transport
JCQ37_RS09495	COG0531	amino acid
JCQ37_RS09505	COG0706	membrane insertase activity
JCQ37_RS09510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JCQ37_RS09520	COG3275	phosphorelay sensor kinase activity
JCQ37_RS09525	COG3279	Response regulator of the LytR AlgR family
JCQ37_RS09530	COG1380	Effector of murein hydrolase LrgA
JCQ37_RS09535	COG1346	cytolysis
JCQ37_RS09540	COG1174	glycine betaine transport
JCQ37_RS09560	COG1063	alcohol dehydrogenase
JCQ37_RS09570	COG0531	amino acid
JCQ37_RS09575	COG2272	Belongs to the type-B carboxylesterase lipase family
JCQ37_RS09580	COG2814	Major facilitator Superfamily
JCQ37_RS09585	COG0390	transport system, permease component
JCQ37_RS09590	COG4619	ABC transporter
JCQ37_RS09605	COG0069	glutamate synthase activity
JCQ37_RS09615	COG1363	Peptidase, m42
JCQ37_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ37_RS09635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JCQ37_RS09640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JCQ37_RS09645	COG4221	oxidoreductase activity
JCQ37_RS09660	COG0556	nucleotide-excision repair
JCQ37_RS09665	COG0494	nUDIX hydrolase
JCQ37_RS09670	COG0438	transferase activity, transferring glycosyl groups
JCQ37_RS09675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JCQ37_RS09680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JCQ37_RS09685	COG2610	gluconate transmembrane transporter activity
JCQ37_RS09695	COG1802	Transcriptional regulator
JCQ37_RS09700	COG2271	Major facilitator Superfamily
JCQ37_RS09705	COG0789	Transcriptional regulator
JCQ37_RS09720	COG2357	RelA SpoT domain protein
JCQ37_RS09725	COG4876	unkown
JCQ37_RS09740	COG2271	Major facilitator Superfamily
JCQ37_RS09750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JCQ37_RS09760	COG2022	thiamine diphosphate biosynthetic process
JCQ37_RS09765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JCQ37_RS09770	COG0586	Pfam SNARE associated Golgi protein
JCQ37_RS09775	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
JCQ37_RS09785	COG3949	Membrane
JCQ37_RS09790	COG1012	belongs to the aldehyde dehydrogenase family
JCQ37_RS09805	COG2514	catechol 2,3-dioxygenase activity
JCQ37_RS09815	COG1012	belongs to the aldehyde dehydrogenase family
JCQ37_RS09820	COG0778	Nitroreductase
JCQ37_RS09825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JCQ37_RS09835	COG3764	Sortase (surface protein transpeptidase)
JCQ37_RS09860	COG1760	l-serine dehydratase
JCQ37_RS09865	COG1760	l-serine dehydratase
JCQ37_RS09880	COG1070	Carbohydrate kinase
JCQ37_RS09890	COG1869	D-ribose catabolic process
JCQ37_RS09895	COG4975	Glucose uptake
JCQ37_RS09910	COG2843	Capsule synthesis protein
JCQ37_RS09920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JCQ37_RS09935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JCQ37_RS09945	COG1063	alcohol dehydrogenase
JCQ37_RS09955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JCQ37_RS09955	COG2190	(PTS) system
JCQ37_RS09955	COG1263	PTS System
JCQ37_RS09960	COG0028	Belongs to the TPP enzyme family
JCQ37_RS09965	COG1346	cytolysis
JCQ37_RS09970	COG1380	Effector of murein hydrolase LrgA
JCQ37_RS09975	COG0583	DNA-binding transcription factor activity
JCQ37_RS09995	COG3425	synthase
JCQ37_RS10025	COG1012	belongs to the aldehyde dehydrogenase family
JCQ37_RS10030	COG1028	Short-chain dehydrogenase reductase Sdr
JCQ37_RS10040	COG2217	Heavy metal translocating P-type atpase
JCQ37_RS10045	COG2608	mercury ion transmembrane transporter activity
JCQ37_RS10055	COG0436	Aminotransferase
JCQ37_RS10060	COG3942	CHAP domain
JCQ37_RS10070	COG0741	lytic transglycosylase activity
JCQ37_RS10085	COG1113	amino acid transport
JCQ37_RS10090	COG3001	Fructosamine kinase
JCQ37_RS10095	COG0167	dihydroorotate dehydrogenase activity
JCQ37_RS10110	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JCQ37_RS10125	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JCQ37_RS10130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JCQ37_RS10135	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JCQ37_RS10145	COG3527	Alpha-acetolactate decarboxylase
JCQ37_RS10150	COG0028	Belongs to the TPP enzyme family
JCQ37_RS10155	COG0039	L-malate dehydrogenase activity
JCQ37_RS10160	COG0583	DNA-binding transcription factor activity
JCQ37_RS10165	COG0531	amino acid
JCQ37_RS10195	COG0446	pyridine nucleotide-disulphide oxidoreductase
JCQ37_RS10200	COG3588	fructose-bisphosphate aldolase
JCQ37_RS10210	COG0579	oxidoreductase
JCQ37_RS10215	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JCQ37_RS10220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JCQ37_RS10220	COG0574	Belongs to the PEP-utilizing enzyme family
JCQ37_RS10225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JCQ37_RS10240	COG1473	amidohydrolase
JCQ37_RS10245	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
JCQ37_RS10250	COG1012	belongs to the aldehyde dehydrogenase family
JCQ37_RS10255	COG1510	regulation of RNA biosynthetic process
JCQ37_RS10265	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JCQ37_RS10270	COG0602	queuosine metabolic process
JCQ37_RS10275	COG1328	CTP reductase activity
JCQ37_RS10285	COG0529	Catalyzes the synthesis of activated sulfate
JCQ37_RS10290	COG2046	Belongs to the sulfate adenylyltransferase family
JCQ37_RS10295	COG0730	response to heat
JCQ37_RS10310	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JCQ37_RS10315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JCQ37_RS10320	COG0175	sulfate reduction
JCQ37_RS10325	COG0386	Belongs to the glutathione peroxidase family
JCQ37_RS10335	COG1846	Transcriptional regulator
JCQ37_RS10360	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JCQ37_RS10375	COG1136	(ABC) transporter
JCQ37_RS10380	COG2205	protein histidine kinase activity
JCQ37_RS10395	COG1785	Belongs to the alkaline phosphatase family
JCQ37_RS10400	COG0702	epimerase
JCQ37_RS10405	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JCQ37_RS10415	COG4195	phage-related replication protein
JCQ37_RS10425	COG1196	nuclear chromosome segregation
JCQ37_RS10440	COG3682	Transcriptional regulator
JCQ37_RS10550	COG1136	(ABC) transporter
JCQ37_RS10555	COG0577	efflux transmembrane transporter activity
JCQ37_RS10570	COG0577	efflux transmembrane transporter activity
JCQ37_RS10575	COG1136	(ABC) transporter
JCQ37_RS10610	COG1475	DNA binding
JCQ37_RS10615	COG0357	Ribosomal RNA small subunit methyltransferase G
JCQ37_RS10620	COG0445	tRNA wobble uridine modification
JCQ37_RS10625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JCQ37_RS10630	COG0594	ribonuclease P activity
JCQ37_RS10640	COG1682	transport, permease protein
JCQ37_RS10675	COG2348	transferase activity, transferring amino-acyl groups