locus-tag	class	description
DP17_RS00010	COG0287	Prephenate dehydrogenase
DP17_RS00015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DP17_RS00020	COG0512	Glutamine amidotransferase of anthranilate synthase
DP17_RS00020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DP17_RS00025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DP17_RS00030	COG0134	indole-3-glycerol-phosphate synthase activity
DP17_RS00035	COG0135	phosphoribosylanthranilate isomerase activity
DP17_RS00040	COG0133	tryptophan synthase activity
DP17_RS00045	COG0159	tryptophan synthase activity
DP17_RS00055	COG2348	transferase activity, transferring amino-acyl groups
DP17_RS00060	COG2348	transferase activity, transferring amino-acyl groups
DP17_RS00070	COG4607	ABC-type enterochelin transport system periplasmic component
DP17_RS00105	COG0704	Plays a role in the regulation of phosphate uptake
DP17_RS00110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DP17_RS00115	COG0581	inorganic phosphate transmembrane transporter activity
DP17_RS00120	COG0573	inorganic phosphate transmembrane transporter activity
DP17_RS00125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DP17_RS00130	COG2996	Protein conserved in bacteria
DP17_RS00135	COG0488	(ABC) transporter
DP17_RS00145	COG0527	aspartate kinase activity
DP17_RS00150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DP17_RS00155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DP17_RS00160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DP17_RS00165	COG2171	N-acyltransferase activity
DP17_RS00170	COG1473	amidohydrolase
DP17_RS00190	COG1131	(ABC) transporter
DP17_RS00200	COG1278	Cold shock
DP17_RS00210	COG1254	Belongs to the acylphosphatase family
DP17_RS00220	COG3853	Toxic anion resistance protein (TelA)
DP17_RS00225	COG1114	Component of the transport system for branched-chain amino acids
DP17_RS00230	COG4548	von Willebrand factor, type A
DP17_RS00235	COG0714	Associated with various cellular activities
DP17_RS00260	COG1131	(ABC) transporter
DP17_RS00300	COG0582	viral genome integration into host DNA
DP17_RS00310	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP17_RS00315	COG0567	Dehydrogenase, E1 component
DP17_RS00320	COG5002	protein histidine kinase activity
DP17_RS00325	COG0745	RESPONSE REGULATOR receiver
DP17_RS00330	COG1349	DNA-binding transcription factor activity
DP17_RS00335	COG0534	Mate efflux family protein
DP17_RS00345	COG0395	ABC-type sugar transport system, permease component
DP17_RS00355	COG4209	transmembrane transport
DP17_RS00360	COG3842	ATPase activity
DP17_RS00365	COG0671	phosphoesterase, PA-phosphatase related
DP17_RS00370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DP17_RS00380	COG0793	Belongs to the peptidase S41A family
DP17_RS00385	COG4479	Belongs to the UPF0346 family
DP17_RS00390	COG2190	(PTS) system
DP17_RS00395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DP17_RS00420	COG1136	(ABC) transporter
DP17_RS00435	COG1413	lyase activity
DP17_RS00445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DP17_RS00455	COG1196	nuclear chromosome segregation
DP17_RS00455	COG1511	domain protein
DP17_RS00455	COG4372	Transposase
DP17_RS00460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DP17_RS00465	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DP17_RS00475	COG0116	Belongs to the methyltransferase superfamily
DP17_RS00480	COG3599	regulation of cell shape
DP17_RS00485	COG4474	Belongs to the UPF0398 family
DP17_RS00495	COG3331	DNA recombination
DP17_RS00500	COG4499	WXG100 protein secretion system (Wss), protein YukC
DP17_RS00500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP17_RS00510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DP17_RS00515	COG3935	DnaD domain protein
DP17_RS00520	COG0017	Asparaginyl-tRNA synthetase
DP17_RS00525	COG1199	ATP-dependent helicase activity
DP17_RS00525	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DP17_RS00530	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DP17_RS00530	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DP17_RS00535	COG0617	tRNA 3'-terminal CCA addition
DP17_RS00540	COG0438	transferase activity, transferring glycosyl groups
DP17_RS00545	COG1694	Mazg nucleotide pyrophosphohydrolase
DP17_RS00550	COG2738	Putative neutral zinc metallopeptidase
DP17_RS00555	COG4347	Protein of unknown function (DUF1405)
DP17_RS00560	COG5582	Belongs to the UPF0302 family
DP17_RS00570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DP17_RS00575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DP17_RS00580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DP17_RS00585	COG0105	UTP biosynthetic process
DP17_RS00595	COG2226	methyltransferase
DP17_RS00610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DP17_RS00615	COG1160	GTP binding
DP17_RS00620	COG0539	negative regulation of cytoplasmic translation
DP17_RS00625	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DP17_RS00630	COG0252	asparaginase activity
DP17_RS00635	COG0492	ferredoxin-NADP+ reductase activity
DP17_RS00640	COG1388	LysM domain
DP17_RS00645	COG0514	ATP-dependent DNA helicase (RecQ)
DP17_RS00655	COG1141	Ferredoxin
DP17_RS00670	COG0745	RESPONSE REGULATOR receiver
DP17_RS00675	COG1187	pseudouridine synthase activity
DP17_RS00680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DP17_RS00685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DP17_RS00690	COG1547	Domain of unknown function (DUF309)
DP17_RS00695	COG4974	Belongs to the 'phage' integrase family
DP17_RS00700	COG0735	belongs to the Fur family
DP17_RS00705	COG0494	nUDIX hydrolase
DP17_RS00710	COG0667	Aldo Keto reductase
DP17_RS00715	COG1028	Short-chain dehydrogenase reductase Sdr
DP17_RS00720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DP17_RS00725	COG1234	tRNA 3'-trailer cleavage
DP17_RS00730	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DP17_RS00740	COG0366	Alpha amylase catalytic
DP17_RS00745	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DP17_RS00750	COG2195	Cleaves the N-terminal amino acid of tripeptides
DP17_RS00755	COG4129	membrane
DP17_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP17_RS00770	COG0022	dehydrogenase e1 component
DP17_RS00775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DP17_RS00780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP17_RS00785	COG0497	DNA recombination
DP17_RS00790	COG1438	arginine binding
DP17_RS00800	COG1722	exodeoxyribonuclease VII activity
DP17_RS00805	COG1570	exodeoxyribonuclease VII activity
DP17_RS00810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP17_RS00815	COG1302	Protein conserved in bacteria
DP17_RS00820	COG0439	Biotin carboxylase
DP17_RS00825	COG0511	ligase activity, forming carbon-carbon bonds
DP17_RS00830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DP17_RS00840	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DP17_RS00845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DP17_RS00850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DP17_RS00855	COG0006	proline dipeptidase activity
DP17_RS00870	COG0095	Lipoate-protein ligase
DP17_RS00875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DP17_RS00885	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DP17_RS00890	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DP17_RS00895	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DP17_RS00900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DP17_RS00915	COG4537	Required for transformation and DNA binding
DP17_RS00920	COG1459	type II secretion system
DP17_RS00925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DP17_RS00935	COG0011	TIGRFAM Protein of
DP17_RS00940	COG1940	carbohydrate kinase activity
DP17_RS00945	COG4483	Protein conserved in bacteria
DP17_RS00955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DP17_RS00960	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DP17_RS00965	COG0768	penicillin binding
DP17_RS00970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DP17_RS00975	COG0735	belongs to the Fur family
DP17_RS00980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP17_RS00985	COG1121	(ABC) transporter
DP17_RS00990	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DP17_RS00995	COG0513	Belongs to the DEAD box helicase family
DP17_RS01000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DP17_RS01005	COG2384	SAM-dependent methyltransferase
DP17_RS01010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DP17_RS01015	COG0358	DNA primase activity
DP17_RS01020	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DP17_RS01025	COG0517	IMP dehydrogenase activity
DP17_RS01030	COG0423	glycine-tRNA ligase activity
DP17_RS01035	COG1381	Involved in DNA repair and RecF pathway recombination
DP17_RS01040	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DP17_RS01045	COG0295	cytidine deaminase activity
DP17_RS01050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DP17_RS01055	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DP17_RS01060	COG1702	phosphate starvation-inducible protein PhoH
DP17_RS01070	COG4864	UPF0365 protein
DP17_RS01075	COG1030	water channel activity
DP17_RS01085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DP17_RS01090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DP17_RS01095	COG2264	protein methyltransferase activity
DP17_RS01100	COG0484	heat shock protein binding
DP17_RS01105	COG0443	Heat shock 70 kDa protein
DP17_RS01110	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DP17_RS01115	COG1420	regulation of RNA biosynthetic process
DP17_RS01120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DP17_RS01125	COG0481	GTPase activity
DP17_RS01130	COG0268	Binds directly to 16S ribosomal RNA
DP17_RS01135	COG1466	dna polymerase III delta subunit
DP17_RS01140	COG2333	competence protein COMEC
DP17_RS01140	COG0658	competence protein
DP17_RS01145	COG2131	deaminase
DP17_RS01155	COG2226	methyltransferase
DP17_RS01160	COG0799	negative regulation of ribosome biogenesis
DP17_RS01165	COG1713	HD superfamily hydrolase involved in NAD metabolism
DP17_RS01170	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DP17_RS01175	COG1534	Rna-binding protein
DP17_RS01180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DP17_RS01185	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DP17_RS01190	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DP17_RS01195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DP17_RS01200	COG1914	H( )-stimulated, divalent metal cation uptake system
DP17_RS01205	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DP17_RS01210	COG0439	Biotin carboxylase
DP17_RS01215	COG0511	ligase activity, forming carbon-carbon bonds
DP17_RS01220	COG1984	allophanate hydrolase subunit 2
DP17_RS01225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DP17_RS01240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DP17_RS01245	COG0572	uridine kinase
DP17_RS01250	COG0826	peptidase U32
DP17_RS01255	COG0826	peptidase U32
DP17_RS01265	COG3906	Belongs to the UPF0473 family
DP17_RS01270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DP17_RS01275	COG4472	Bacterial protein of unknown function (DUF965)
DP17_RS01280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DP17_RS01285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DP17_RS01295	COG0482	sulfurtransferase activity
DP17_RS01300	COG1104	cysteine desulfurase activity
DP17_RS01305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DP17_RS01315	COG1959	2 iron, 2 sulfur cluster binding
DP17_RS01320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DP17_RS01325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DP17_RS01330	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DP17_RS01335	COG0124	histidyl-tRNA synthetase
DP17_RS01340	COG0860	N-Acetylmuramoyl-L-alanine amidase
DP17_RS01345	COG1490	D-aminoacyl-tRNA deacylase activity
DP17_RS01350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DP17_RS01355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DP17_RS01360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DP17_RS01360	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DP17_RS01365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DP17_RS01365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DP17_RS01370	COG1862	Preprotein translocase
DP17_RS01375	COG0343	queuine tRNA-ribosyltransferase activity
DP17_RS01380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DP17_RS01385	COG2255	four-way junction helicase activity
DP17_RS01390	COG0632	four-way junction helicase activity
DP17_RS01395	COG4492	Belongs to the UPF0735 family
DP17_RS01400	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DP17_RS01405	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DP17_RS01410	COG2868	ribosomal protein
DP17_RS01415	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DP17_RS01445	COG2003	Belongs to the UPF0758 family
DP17_RS01455	COG0285	dihydrofolate synthase activity
DP17_RS01460	COG0525	valine-tRNA ligase activity
DP17_RS01465	COG2818	Glycosylase
DP17_RS01475	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DP17_RS01480	COG0113	porphobilinogen synthase activity
DP17_RS01490	COG0181	hydroxymethylbilane synthase activity
DP17_RS01500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DP17_RS01505	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DP17_RS01510	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DP17_RS01515	COG0544	peptidyl-prolyl cis-trans isomerase activity
DP17_RS01525	COG4112	unkown
DP17_RS01530	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DP17_RS01535	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DP17_RS01540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DP17_RS01545	COG0833	amino acid
DP17_RS01550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DP17_RS01555	COG1484	DNA-dependent DNA replication
DP17_RS01560	COG3611	Membrane attachment protein
DP17_RS01565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DP17_RS01570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DP17_RS01580	COG0237	dephospho-CoA kinase activity
DP17_RS01590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DP17_RS01590	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DP17_RS01595	COG5002	protein histidine kinase activity
DP17_RS01600	COG0745	RESPONSE REGULATOR receiver
DP17_RS01605	COG0538	isocitrate dehydrogenase activity
DP17_RS01610	COG0372	Belongs to the citrate synthase family
DP17_RS01615	COG1113	amino acid transport
DP17_RS01620	COG0469	pyruvate kinase activity
DP17_RS01625	COG0205	6-phosphofructokinase activity
DP17_RS01630	COG0825	malonyl-CoA metabolic process
DP17_RS01635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DP17_RS01640	COG0281	malic enzyme
DP17_RS01645	COG0587	DNA-directed DNA polymerase activity
DP17_RS01650	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DP17_RS01655	COG4109	DRTGG domain
DP17_RS01665	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DP17_RS01670	COG0006	proline dipeptidase activity
DP17_RS01675	COG0686	Belongs to the AlaDH PNT family
DP17_RS01680	COG0589	response to stress
DP17_RS01690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DP17_RS01695	COG0827	DNA restriction-modification system
DP17_RS01700	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DP17_RS01710	COG0301	tRNA thio-modification
DP17_RS01720	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DP17_RS01725	COG1956	GAF domain-containing protein
DP17_RS01730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DP17_RS01735	COG0584	glycerophosphoryl diester phosphodiesterase
DP17_RS01740	COG1764	response to oxidative stress
DP17_RS01745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DP17_RS01750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DP17_RS01760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP17_RS01760	COG1263	PTS System
DP17_RS01765	COG0204	Acyl-transferase
DP17_RS01770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP17_RS01775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DP17_RS01785	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DP17_RS01790	COG1609	Transcriptional regulator
DP17_RS01795	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DP17_RS01795	COG1605	Chorismate mutase
DP17_RS01805	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DP17_RS01810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DP17_RS01815	COG1674	ftsk spoiiie
DP17_RS01820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP17_RS01825	COG4848	Belongs to the UPF0354 family
DP17_RS01830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DP17_RS01835	COG1363	Peptidase, m42
DP17_RS01845	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DP17_RS01850	COG0510	thiamine kinase activity
DP17_RS01855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DP17_RS01860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DP17_RS01870	COG1187	pseudouridine synthase activity
DP17_RS01875	COG2244	polysaccharide biosynthetic process
DP17_RS01880	COG2081	HI0933 family
DP17_RS01895	COG0495	leucyl-tRNA aminoacylation
DP17_RS01900	COG2814	Major facilitator Superfamily
DP17_RS01905	COG1242	4 iron, 4 sulfur cluster binding
DP17_RS01910	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DP17_RS01925	COG2267	carboxylic ester hydrolase activity
DP17_RS01930	COG0506	proline dehydrogenase activity
DP17_RS01940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DP17_RS01945	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DP17_RS01945	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DP17_RS01955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DP17_RS01955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DP17_RS01965	COG5632	N-Acetylmuramoyl-L-alanine amidase
DP17_RS01965	COG4193	domain, Protein
DP17_RS01965	COG3266	domain, Protein
DP17_RS01990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DP17_RS02000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DP17_RS02005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DP17_RS02020	COG0656	L-ascorbic acid biosynthetic process
DP17_RS02030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DP17_RS02035	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DP17_RS02040	COG1506	peptidase
DP17_RS02045	COG0494	nUDIX hydrolase
DP17_RS02050	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DP17_RS02060	COG0318	PFAM AMP-dependent synthetase and ligase
DP17_RS02125	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DP17_RS02130	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DP17_RS02135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DP17_RS02140	COG2329	Antibiotic biosynthesis monooxygenase
DP17_RS02150	COG4473	ABC transporter
DP17_RS02155	COG1131	(ABC) transporter
DP17_RS02160	COG0537	adenosine 5'-monophosphoramidase activity
DP17_RS02175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DP17_RS02180	COG3481	metal-dependent phosphohydrolase, HD sub domain
DP17_RS02190	COG0420	3'-5' exonuclease activity
DP17_RS02195	COG3679	Belongs to the UPF0342 family
DP17_RS02200	COG4399	Belongs to the UPF0754 family
DP17_RS02210	COG2197	response regulator
DP17_RS02215	COG2203	Gaf domain
DP17_RS02215	COG4585	Histidine kinase
DP17_RS02220	COG0564	pseudouridine synthase activity
DP17_RS02225	COG0114	fumarate hydratase activity
DP17_RS02250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DP17_RS02260	COG1126	abc transporter atp-binding protein
DP17_RS02265	COG0765	amino acid transport
DP17_RS02425	COG0735	belongs to the Fur family
DP17_RS02430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP17_RS02435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DP17_RS02440	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DP17_RS02445	COG4129	membrane
DP17_RS02455	COG3557	Belongs to the UPF0374 family
DP17_RS02465	COG1988	membrane-bound metal-dependent
DP17_RS02475	COG1388	LysM domain
DP17_RS02475	COG1134	teichoic acid transport
DP17_RS02485	COG2137	regulation of response to DNA damage stimulus
DP17_RS02490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DP17_RS02495	COG0693	protein deglycase activity
DP17_RS02505	COG0535	radical SAM domain protein
DP17_RS02510	COG1607	acyl-coa hydrolase
DP17_RS02515	COG2309	aminopeptidase activity
DP17_RS02520	COG4840	Belongs to the UPF0435 family
DP17_RS02525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP17_RS02535	COG1295	ribonuclease BN
DP17_RS02540	COG2197	response regulator
DP17_RS02545	COG4585	Histidine kinase
DP17_RS02560	COG0024	Methionine aminopeptidase
DP17_RS02565	COG4129	membrane
DP17_RS02585	COG1528	Iron-storage protein
DP17_RS02595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DP17_RS02605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DP17_RS02610	COG1597	lipid kinase activity
DP17_RS02615	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DP17_RS02620	COG0154	amidase activity
DP17_RS02625	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DP17_RS02630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DP17_RS02635	COG4851	CamS sex pheromone cAM373 precursor
DP17_RS02640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DP17_RS02645	COG0210	DNA helicase
DP17_RS02650	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DP17_RS02655	COG4496	protein, YerC YecD
DP17_RS02660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DP17_RS02670	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DP17_RS02675	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DP17_RS02680	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DP17_RS02690	COG0077	Prephenate dehydratase
DP17_RS02705	COG1335	isochorismatase
DP17_RS02710	COG1227	inorganic diphosphatase activity
DP17_RS02715	COG1012	belongs to the aldehyde dehydrogenase family
DP17_RS02720	COG2706	6-phosphogluconolactonase activity
DP17_RS02765	COG1131	(ABC) transporter
DP17_RS02775	COG1131	(ABC) transporter
DP17_RS02780	COG1725	Transcriptional regulator
DP17_RS02830	COG0459	protein refolding
DP17_RS02835	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DP17_RS02865	COG3290	protein histidine kinase activity
DP17_RS02870	COG3279	Response regulator of the LytR AlgR family
DP17_RS02875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DP17_RS02880	COG1621	beta-fructofuranosidase activity
DP17_RS02885	COG1609	Transcriptional regulator
DP17_RS02890	COG0004	ammonium transporteR
DP17_RS02895	COG0425	Belongs to the sulfur carrier protein TusA family
DP17_RS02900	COG2391	methyltransferase activity
DP17_RS02910	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DP17_RS02915	COG0488	(ABC) transporter
DP17_RS02920	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DP17_RS02925	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DP17_RS02930	COG0456	acetyltransferase
DP17_RS02935	COG1214	PFAM Peptidase M22, glycoprotease
DP17_RS02940	COG0802	atpase or kinase
DP17_RS02945	COG0129	dihydroxy-acid dehydratase activity
DP17_RS02950	COG0028	Belongs to the TPP enzyme family
DP17_RS02960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DP17_RS02965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DP17_RS02970	COG0473	3-isopropylmalate dehydrogenase activity
DP17_RS02975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DP17_RS02980	COG0066	3-isopropylmalate dehydratase activity
DP17_RS02985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DP17_RS03015	COG3091	SprT-like family
DP17_RS03020	COG2183	response to ionizing radiation
DP17_RS03025	COG1191	sigma factor activity
DP17_RS03040	COG2208	phosphoserine phosphatase activity
DP17_RS03045	COG2337	Toxic component of a toxin-antitoxin (TA) module
DP17_RS03055	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DP17_RS03060	COG0736	holo-[acyl-carrier-protein] synthase activity
DP17_RS03065	COG3402	PFAM membrane-flanked domain
DP17_RS03070	COG3428	Bacterial PH domain
DP17_RS03080	COG0513	Belongs to the DEAD box helicase family
DP17_RS03085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DP17_RS03090	COG1181	Belongs to the D-alanine--D-alanine ligase family
DP17_RS03095	COG0772	Belongs to the SEDS family
DP17_RS03110	COG1937	Protein conserved in bacteria
DP17_RS03115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DP17_RS03120	COG1418	mRNA catabolic process
DP17_RS03125	COG0706	membrane insertase activity
DP17_RS03130	COG0352	thiamine-phosphate diphosphorylase activity
DP17_RS03135	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DP17_RS03145	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DP17_RS03150	COG1388	LysM domain
DP17_RS03155	COG0629	single-stranded DNA binding
DP17_RS03165	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DP17_RS03170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DP17_RS03180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DP17_RS03185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DP17_RS03190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DP17_RS03195	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DP17_RS03200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DP17_RS03205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DP17_RS03215	COG0356	it plays a direct role in the translocation of protons across the membrane
DP17_RS03225	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DP17_RS03230	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DP17_RS03235	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DP17_RS03240	COG4475	Protein of unknown function (DUF436)
DP17_RS03245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP17_RS03250	COG0009	L-threonylcarbamoyladenylate synthase
DP17_RS03255	COG2890	protein-(glutamine-N5) methyltransferase activity
DP17_RS03260	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DP17_RS03265	COG1435	thymidine kinase activity
DP17_RS03270	COG0254	rRNA binding
DP17_RS03275	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DP17_RS03280	COG1012	belongs to the aldehyde dehydrogenase family
DP17_RS03295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DP17_RS03300	COG0191	fructose-bisphosphate aldolase activity
DP17_RS03310	COG0504	CTP synthase activity
DP17_RS03315	COG3343	RNA polymerase activity
DP17_RS03325	COG5146	pantothenate kinase activity
DP17_RS03345	COG1854	S-ribosylhomocysteine lyase activity
DP17_RS03355	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DP17_RS03360	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DP17_RS03365	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DP17_RS03370	COG0813	purine-nucleoside phosphorylase activity
DP17_RS03375	COG0783	Belongs to the Dps family
DP17_RS03395	COG1482	cell wall glycoprotein biosynthetic process
DP17_RS03400	COG0702	epimerase
DP17_RS03405	COG0640	Transcriptional regulator
DP17_RS03425	COG0561	phosphatase activity
DP17_RS03430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DP17_RS03435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DP17_RS03445	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DP17_RS03500	COG0489	protein tyrosine kinase activity
DP17_RS03505	COG2814	Major facilitator Superfamily
DP17_RS03525	COG4284	Utp--glucose-1-phosphate uridylyltransferase
DP17_RS03530	COG1988	membrane-bound metal-dependent
DP17_RS03540	COG2329	Antibiotic biosynthesis monooxygenase
DP17_RS03545	COG3314	Sporulation integral membrane protein YlbJ
DP17_RS03550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP17_RS03555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP17_RS03560	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DP17_RS03565	COG3457	Alanine racemase
DP17_RS03570	COG4264	IucA IucC family
DP17_RS03575	COG2814	Major facilitator Superfamily
DP17_RS03580	COG4264	IucA IucC family
DP17_RS03585	COG1302	Protein conserved in bacteria
DP17_RS03600	COG0604	alcohol dehydrogenase
DP17_RS03605	COG2130	NADP-dependent
DP17_RS03610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DP17_RS03620	COG2723	6-phospho-beta-galactosidase activity
DP17_RS03625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP17_RS03625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DP17_RS03630	COG1447	Phosphotransferase system cellobiose-specific component IIA
DP17_RS03635	COG3684	Belongs to the aldolase LacD family
DP17_RS03640	COG1105	Belongs to the carbohydrate kinase PfkB family
DP17_RS03645	COG0698	ribose 5-phosphate isomerase
DP17_RS03650	COG0698	ribose 5-phosphate isomerase
DP17_RS03655	COG1349	DNA-binding transcription factor activity
DP17_RS03660	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DP17_RS03665	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DP17_RS03670	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DP17_RS03675	COG0101	tRNA pseudouridine synthase activity
DP17_RS03685	COG1122	ATPase activity
DP17_RS03690	COG1122	ATPase activity
DP17_RS03695	COG0203	ribosomal protein L17
DP17_RS03700	COG0202	RNA polymerase activity
DP17_RS03705	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DP17_RS03710	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DP17_RS03715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DP17_RS03720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DP17_RS03725	COG0563	adenylate kinase activity
DP17_RS03730	COG0201	protein transport
DP17_RS03735	COG0200	Binds to the 23S rRNA
DP17_RS03740	COG1841	ribosomal large subunit assembly
DP17_RS03745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DP17_RS03750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DP17_RS03755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DP17_RS03760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DP17_RS03765	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DP17_RS03770	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DP17_RS03775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DP17_RS03780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DP17_RS03785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DP17_RS03795	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DP17_RS03800	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DP17_RS03805	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DP17_RS03810	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DP17_RS03815	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DP17_RS03820	COG0089	rRNA binding
DP17_RS03825	COG0088	Forms part of the polypeptide exit tunnel
DP17_RS03830	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DP17_RS03845	COG2252	PERMEase
DP17_RS03850	COG0551	DNA topoisomerase type I activity
DP17_RS03850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DP17_RS03855	COG4975	Glucose uptake
DP17_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
DP17_RS03880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DP17_RS03885	COG2348	transferase activity, transferring amino-acyl groups
DP17_RS03900	COG2814	Major facilitator Superfamily
DP17_RS03915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DP17_RS03920	COG0746	molybdenum cofactor guanylyltransferase activity
DP17_RS03930	COG0314	molybdopterin synthase activity
DP17_RS03940	COG0303	'Molybdopterin
DP17_RS03945	COG0315	cyclic pyranopterin monophosphate synthase activity
DP17_RS03950	COG0521	Mo-molybdopterin cofactor biosynthetic process
DP17_RS03955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DP17_RS03960	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DP17_RS03965	COG4149	molybdate abc transporter
DP17_RS03970	COG0725	ABC transporter, periplasmic molybdate-binding protein
DP17_RS03985	COG1268	BioY protein
DP17_RS03995	COG1960	acyl-CoA dehydrogenase activity
DP17_RS04005	COG0831	urea catabolic process
DP17_RS04010	COG0832	Belongs to the urease beta subunit family
DP17_RS04015	COG0804	urea catabolic process
DP17_RS04020	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DP17_RS04025	COG0830	nickel cation binding
DP17_RS04030	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DP17_RS04035	COG0829	nickel cation binding
DP17_RS04065	COG3942	CHAP domain
DP17_RS04070	COG1757	Na H antiporter
DP17_RS04085	COG3942	CHAP domain
DP17_RS04090	COG2076	Multidrug Resistance protein
DP17_RS04095	COG2076	Multidrug Resistance protein
DP17_RS04100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP17_RS04120	COG1316	TRANSCRIPTIONal
DP17_RS04125	COG0483	inositol monophosphate 1-phosphatase activity
DP17_RS04130	COG2378	regulation of single-species biofilm formation
DP17_RS04135	COG1266	CAAX protease self-immunity
DP17_RS04150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DP17_RS04155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP17_RS04155	COG1263	PTS System
DP17_RS04165	COG1113	amino acid transport
DP17_RS04195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DP17_RS04205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP17_RS04205	COG1263	PTS System
DP17_RS04210	COG1737	Transcriptional regulator
DP17_RS04245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DP17_RS04250	COG1028	Short-chain dehydrogenase reductase Sdr
DP17_RS04255	COG1473	amidohydrolase
DP17_RS04260	COG0010	Belongs to the arginase family
DP17_RS04265	COG1266	CAAX protease self-immunity
DP17_RS04280	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DP17_RS04285	COG2258	MOSC domain
DP17_RS04290	COG2017	converts alpha-aldose to the beta-anomer
DP17_RS04295	COG1069	ribulokinase activity
DP17_RS04305	COG2094	Belongs to the DNA glycosylase MPG family
DP17_RS04325	COG0786	glutamate:sodium symporter activity
DP17_RS04330	COG1304	FMN binding
DP17_RS04335	COG0598	Magnesium transport protein CorA
DP17_RS04350	COG0657	acetylesterase activity
DP17_RS04360	COG2814	Major facilitator Superfamily
DP17_RS04365	COG1566	PFAM secretion protein HlyD family protein
DP17_RS04375	COG2814	Major facilitator Superfamily
DP17_RS04380	COG4640	response to antibiotic
DP17_RS04395	COG1136	(ABC) transporter
DP17_RS04400	COG0577	efflux transmembrane transporter activity
DP17_RS04405	COG0745	RESPONSE REGULATOR receiver
DP17_RS04410	COG5002	protein histidine kinase activity
DP17_RS04410	COG3850	Histidine kinase
DP17_RS04415	COG0579	oxidoreductase
DP17_RS04420	COG0438	transferase activity, transferring glycosyl groups
DP17_RS04425	COG1620	l-lactate permease
DP17_RS04430	COG0463	Glycosyl transferase, family 2
DP17_RS04430	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DP17_RS04440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DP17_RS04440	COG0463	Glycosyl transferase, family 2
DP17_RS04445	COG0456	acetyltransferase
DP17_RS04450	COG0604	alcohol dehydrogenase
DP17_RS04495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP17_RS04495	COG1263	PTS System
DP17_RS04510	COG3871	stress protein (general stress protein 26)
DP17_RS04530	COG0778	Nitroreductase
DP17_RS04535	COG1846	Transcriptional regulator
DP17_RS04540	COG2223	nitrite transmembrane transporter activity
DP17_RS04545	COG2197	response regulator
DP17_RS04550	COG4585	Histidine kinase
DP17_RS04560	COG2181	nitrate reductase activity
DP17_RS04570	COG1140	nitrate reductase beta subunit
DP17_RS04575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DP17_RS04585	COG2146	nitrite reductase [NAD(P)H] activity
DP17_RS04590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DP17_RS04600	COG0747	negative chemotaxis
DP17_RS04610	COG0454	-acetyltransferase
DP17_RS04615	COG2116	formate transmembrane transporter activity
DP17_RS04635	COG2348	transferase activity, transferring amino-acyl groups
DP17_RS04645	COG1126	abc transporter atp-binding protein
DP17_RS04650	COG0765	amino acid transport
DP17_RS04655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DP17_RS04660	COG0588	phosphoglycerate mutase activity
DP17_RS04665	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DP17_RS04680	COG1929	Belongs to the glycerate kinase type-1 family
DP17_RS04705	COG1113	amino acid transport
DP17_RS04710	COG0531	amino acid
DP17_RS04720	COG0706	membrane insertase activity
DP17_RS04725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DP17_RS04735	COG3275	phosphorelay sensor kinase activity
DP17_RS04740	COG3279	Response regulator of the LytR AlgR family
DP17_RS04745	COG1380	Effector of murein hydrolase LrgA
DP17_RS04750	COG1346	cytolysis
DP17_RS04755	COG1174	glycine betaine transport
DP17_RS04775	COG1063	alcohol dehydrogenase
DP17_RS04785	COG0531	amino acid
DP17_RS04790	COG2272	Belongs to the type-B carboxylesterase lipase family
DP17_RS04795	COG2814	Major facilitator Superfamily
DP17_RS04800	COG0390	transport system, permease component
DP17_RS04805	COG4619	ABC transporter
DP17_RS04815	COG0069	glutamate synthase activity
DP17_RS04825	COG1363	Peptidase, m42
DP17_RS04835	COG1028	Short-chain dehydrogenase reductase Sdr
DP17_RS04840	COG0248	Ppx GppA phosphatase
DP17_RS04845	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DP17_RS04850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DP17_RS04855	COG4221	oxidoreductase activity
DP17_RS04875	COG0494	nUDIX hydrolase
DP17_RS04880	COG0438	transferase activity, transferring glycosyl groups
DP17_RS04885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DP17_RS04890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DP17_RS04895	COG2610	gluconate transmembrane transporter activity
DP17_RS04905	COG1802	Transcriptional regulator
DP17_RS04910	COG2271	Major facilitator Superfamily
DP17_RS04915	COG0789	Transcriptional regulator
DP17_RS04930	COG2357	RelA SpoT domain protein
DP17_RS04935	COG4876	unkown
DP17_RS04950	COG2271	Major facilitator Superfamily
DP17_RS04960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DP17_RS04970	COG2022	thiamine diphosphate biosynthetic process
DP17_RS04975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DP17_RS04980	COG0586	Pfam SNARE associated Golgi protein
DP17_RS04985	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DP17_RS04995	COG3949	Membrane
DP17_RS05000	COG1012	belongs to the aldehyde dehydrogenase family
DP17_RS05015	COG2514	catechol 2,3-dioxygenase activity
DP17_RS05020	COG1012	belongs to the aldehyde dehydrogenase family
DP17_RS05025	COG0778	Nitroreductase
DP17_RS05030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP17_RS05040	COG1070	Carbohydrate kinase
DP17_RS05055	COG1760	l-serine dehydratase
DP17_RS05060	COG1760	l-serine dehydratase
DP17_RS05075	COG3764	Sortase (surface protein transpeptidase)
DP17_RS05090	COG1869	D-ribose catabolic process
DP17_RS05095	COG4975	Glucose uptake
DP17_RS05110	COG2843	Capsule synthesis protein
DP17_RS05120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DP17_RS05135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DP17_RS05145	COG1063	alcohol dehydrogenase
DP17_RS05160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DP17_RS05160	COG2190	(PTS) system
DP17_RS05160	COG1263	PTS System
DP17_RS05165	COG0028	Belongs to the TPP enzyme family
DP17_RS05170	COG1346	cytolysis
DP17_RS05175	COG1380	Effector of murein hydrolase LrgA
DP17_RS05180	COG0583	DNA-binding transcription factor activity
DP17_RS05200	COG3425	synthase
DP17_RS05205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DP17_RS05230	COG1012	belongs to the aldehyde dehydrogenase family
DP17_RS05235	COG1028	Short-chain dehydrogenase reductase Sdr
DP17_RS05245	COG2217	Heavy metal translocating P-type atpase
DP17_RS05250	COG2608	mercury ion transmembrane transporter activity
DP17_RS05260	COG0436	Aminotransferase
DP17_RS05265	COG3942	CHAP domain
DP17_RS05275	COG0741	lytic transglycosylase activity
DP17_RS05290	COG1113	amino acid transport
DP17_RS05295	COG3001	Fructosamine kinase
DP17_RS05300	COG0167	dihydroorotate dehydrogenase activity
DP17_RS05315	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DP17_RS05330	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DP17_RS05335	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DP17_RS05340	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DP17_RS05350	COG3527	Alpha-acetolactate decarboxylase
DP17_RS05355	COG0028	Belongs to the TPP enzyme family
DP17_RS05360	COG0039	L-malate dehydrogenase activity
DP17_RS05365	COG0583	DNA-binding transcription factor activity
DP17_RS05370	COG0531	amino acid
DP17_RS05400	COG0446	pyridine nucleotide-disulphide oxidoreductase
DP17_RS05405	COG3588	fructose-bisphosphate aldolase
DP17_RS05415	COG0579	oxidoreductase
DP17_RS05420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DP17_RS05425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DP17_RS05425	COG0574	Belongs to the PEP-utilizing enzyme family
DP17_RS05430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DP17_RS05445	COG1473	amidohydrolase
DP17_RS05450	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DP17_RS05455	COG1012	belongs to the aldehyde dehydrogenase family
DP17_RS05460	COG1510	regulation of RNA biosynthetic process
DP17_RS05470	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DP17_RS05475	COG0602	queuosine metabolic process
DP17_RS05480	COG1328	CTP reductase activity
DP17_RS05490	COG0529	Catalyzes the synthesis of activated sulfate
DP17_RS05495	COG2046	Belongs to the sulfate adenylyltransferase family
DP17_RS05500	COG0730	response to heat
DP17_RS05515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DP17_RS05520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DP17_RS05525	COG0175	sulfate reduction
DP17_RS05530	COG0386	Belongs to the glutathione peroxidase family
DP17_RS05535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP17_RS05540	COG1846	Transcriptional regulator
DP17_RS05565	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DP17_RS05580	COG1136	(ABC) transporter
DP17_RS05585	COG2205	protein histidine kinase activity
DP17_RS05600	COG1785	Belongs to the alkaline phosphatase family
DP17_RS05605	COG0702	epimerase
DP17_RS05610	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DP17_RS05620	COG4195	phage-related replication protein
DP17_RS05645	COG3961	Belongs to the TPP enzyme family
DP17_RS05650	COG2843	Capsule synthesis protein
DP17_RS05660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DP17_RS05670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP17_RS05675	COG2235	arginine
DP17_RS05680	COG1438	arginine binding
DP17_RS05685	COG3227	Zinc metalloprotease (Elastase)
DP17_RS05690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DP17_RS05720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP17_RS05720	COG3711	transcriptional antiterminator
DP17_RS05725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DP17_RS05725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP17_RS05725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DP17_RS05730	COG1482	cell wall glycoprotein biosynthetic process
DP17_RS05740	COG3942	CHAP domain
DP17_RS05740	COG1705	Flagellar rod assembly protein muramidase FlgJ
DP17_RS05750	COG1764	response to oxidative stress
DP17_RS05770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DP17_RS05775	COG2814	Major facilitator Superfamily
DP17_RS05800	COG0438	transferase activity, transferring glycosyl groups
DP17_RS05805	COG0653	protein targeting
DP17_RS05815	COG1073	alpha beta
DP17_RS05825	COG0201	protein transport
DP17_RS05845	COG3639	organic phosphonate transmembrane transporter activity
DP17_RS05850	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DP17_RS05865	COG0737	Belongs to the 5'-nucleotidase family
DP17_RS05870	COG2814	Major facilitator Superfamily
DP17_RS05890	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DP17_RS05895	COG0140	phosphoribosyl-ATP diphosphatase activity
DP17_RS05895	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DP17_RS05900	COG0107	imidazoleglycerol-phosphate synthase activity
DP17_RS05905	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DP17_RS05910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DP17_RS05915	COG0131	Imidazoleglycerol-phosphate dehydratase
DP17_RS05920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DP17_RS05925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DP17_RS05930	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DP17_RS05955	COG0579	oxidoreductase
DP17_RS05960	COG2353	YceI-like domain
DP17_RS05970	COG1054	Belongs to the UPF0176 family
DP17_RS05975	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DP17_RS06000	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP17_RS06005	COG0022	dehydrogenase e1 component
DP17_RS06010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DP17_RS06015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP17_RS06020	COG0471	metal ion transport
DP17_RS06025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DP17_RS06030	COG2962	Rard protein
DP17_RS06045	COG2814	Major facilitator Superfamily
DP17_RS06070	COG2814	Major facilitator Superfamily
DP17_RS06085	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DP17_RS06090	COG1461	Dihydroxyacetone kinase
DP17_RS06095	COG2376	Dihydroxyacetone kinase
DP17_RS06105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DP17_RS06110	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DP17_RS06115	COG0346	lactoylglutathione lyase activity
DP17_RS06125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP17_RS06130	COG0549	Belongs to the carbamate kinase family
DP17_RS06135	COG1288	antiporter activity
DP17_RS06170	COG1250	3-hydroxyacyl-CoA dehydrogenase
DP17_RS06175	COG3246	L-lysine catabolic process to acetate
DP17_RS06180	COG1309	transcriptional regulator
DP17_RS06185	COG1114	Component of the transport system for branched-chain amino acids
DP17_RS06190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DP17_RS06195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DP17_RS06200	COG1882	Formate acetyltransferase
DP17_RS06210	COG1124	(ABC) transporter
DP17_RS06215	COG0444	Belongs to the ABC transporter superfamily
DP17_RS06225	COG0601	transmembrane transport
DP17_RS06260	COG1028	Short-chain dehydrogenase reductase Sdr
DP17_RS06270	COG3976	FMN-binding domain protein
DP17_RS06270	COG0431	NADPH-dependent FMN reductase
DP17_RS06270	COG1053	succinate dehydrogenase
DP17_RS06295	COG0523	cobalamin synthesis protein
DP17_RS06325	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
DP17_RS06330	COG0156	8-amino-7-oxononanoate synthase activity
DP17_RS06335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DP17_RS06340	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DP17_RS06420	COG1755	Isoprenylcysteine carboxyl methyltransferase
DP17_RS06425	COG0579	oxidoreductase
DP17_RS06430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DP17_RS06465	COG2814	Major facilitator Superfamily
DP17_RS06480	COG0668	transmembrane transport
DP17_RS06500	COG0640	Transcriptional regulator
DP17_RS06520	COG0446	pyridine nucleotide-disulphide oxidoreductase
DP17_RS06530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DP17_RS06535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP17_RS06540	COG0730	response to heat
DP17_RS06545	COG1937	Protein conserved in bacteria
DP17_RS06550	COG2210	Belongs to the sulfur carrier protein TusA family
DP17_RS06555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DP17_RS06560	COG1388	LysM domain
DP17_RS06565	COG2132	Multicopper oxidase
DP17_RS06570	COG2217	Heavy metal translocating P-type atpase
DP17_RS06595	COG5002	protein histidine kinase activity
DP17_RS06600	COG0745	RESPONSE REGULATOR receiver
DP17_RS06615	COG1131	(ABC) transporter
DP17_RS06620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DP17_RS06635	COG0076	glutamate decarboxylase activity
DP17_RS06655	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DP17_RS06665	COG2235	arginine
DP17_RS06675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DP17_RS06680	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DP17_RS06685	COG0549	Belongs to the carbamate kinase family
DP17_RS06690	COG2801	Transposase and inactivated derivatives
DP17_RS06775	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DP17_RS06780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DP17_RS06790	COG4863	YycH protein
DP17_RS06795	COG5002	protein histidine kinase activity
DP17_RS06800	COG0745	RESPONSE REGULATOR receiver
DP17_RS06815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DP17_RS06820	COG0305	Participates in initiation and elongation during chromosome replication
DP17_RS06825	COG0359	binds to the 23S rRNA
DP17_RS06830	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DP17_RS06840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DP17_RS06860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DP17_RS06865	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DP17_RS06870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DP17_RS06875	COG0187	DNA topoisomerase II activity
DP17_RS06880	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DP17_RS06885	COG2501	S4 domain
DP17_RS06890	COG0592	DNA-directed DNA polymerase activity
DP17_RS06895	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DP17_RS06905	COG0594	ribonuclease P activity
DP17_RS06910	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DP17_RS06915	COG0445	tRNA wobble uridine modification
DP17_RS06920	COG0357	Ribosomal RNA small subunit methyltransferase G
DP17_RS06925	COG1475	DNA binding
DP17_RS06970	COG1136	(ABC) transporter
DP17_RS06975	COG0577	efflux transmembrane transporter activity
DP17_RS06990	COG0577	efflux transmembrane transporter activity
DP17_RS06995	COG1136	(ABC) transporter
DP17_RS07020	COG3266	domain, Protein
DP17_RS07020	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DP17_RS07020	COG4932	domain protein
DP17_RS07020	COG4932	domain protein
DP17_RS07020	COG3266	domain, Protein
DP17_RS07020	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DP17_RS07035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DP17_RS07055	COG4555	ABC transporter
DP17_RS07065	COG1476	TRANSCRIPTIONal
DP17_RS07080	COG0183	Belongs to the thiolase family
DP17_RS07090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DP17_RS07095	COG0646	methionine synthase
DP17_RS07095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DP17_RS07100	COG0626	cystathionine gamma-synthase activity
DP17_RS07105	COG0626	cystathionine gamma-synthase activity
DP17_RS07110	COG1475	DNA binding
DP17_RS07115	COG0668	transmembrane transport
DP17_RS07120	COG4481	Protein conserved in bacteria
DP17_RS07125	COG0012	GTP binding
DP17_RS07140	COG0360	Binds together with S18 to 16S ribosomal RNA
DP17_RS07150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DP17_RS07165	COG1280	lysine exporter protein (LysE YggA)
DP17_RS07185	COG3634	alkyl hydroperoxide reductase activity
DP17_RS07190	COG0450	alkyl hydroperoxide reductase
DP17_RS07200	COG0778	Nitroreductase
DP17_RS07205	COG1823	symporter activity
DP17_RS07210	COG5183	chlorophyll binding
DP17_RS07225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DP17_RS07230	COG2233	PERMEase
DP17_RS07235	COG0516	GMP reductase activity
DP17_RS07235	COG0517	IMP dehydrogenase activity
DP17_RS07240	COG0519	Catalyzes the synthesis of GMP from XMP
DP17_RS07240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DP17_RS07245	COG0582	viral genome integration into host DNA
DP17_RS07310	COG2856	Zn peptidase
DP17_RS07390	COG0655	NAD(P)H dehydrogenase (quinone) activity
DP17_RS07405	COG0523	cobalamin synthesis protein
DP17_RS07410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DP17_RS07415	COG3002	Belongs to the UPF0753 family
DP17_RS07420	COG5609	conserved protein (DUF2294)
DP17_RS07435	COG1647	Serine aminopeptidase, S33
DP17_RS07445	COG0733	neurotransmitter:sodium symporter activity
DP17_RS07460	COG0626	cystathionine gamma-synthase activity
DP17_RS07465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DP17_RS07470	COG2011	ABC-type metal ion transport system permease component
DP17_RS07480	COG3942	CHAP domain
DP17_RS07480	COG1388	LysM domain
DP17_RS07485	COG0438	transferase activity, transferring glycosyl groups
DP17_RS07510	COG0583	DNA-binding transcription factor activity
DP17_RS07515	COG0069	glutamate synthase activity
DP17_RS07515	COG0070	glutamate synthase
DP17_RS07515	COG0067	glutamate synthase
DP17_RS07520	COG0493	'glutamate synthase
DP17_RS07530	COG0583	DNA-binding transcription factor activity
DP17_RS07535	COG2855	membrane
DP17_RS07545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DP17_RS07550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DP17_RS07555	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DP17_RS07580	COG1982	Orn Lys Arg decarboxylase major
DP17_RS07585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DP17_RS07590	COG3870	Protein conserved in bacteria
DP17_RS07595	COG0470	DNA polymerase III
DP17_RS07600	COG1774	PSP1 C-terminal conserved region
DP17_RS07605	COG4467	Involved in initiation control of chromosome replication
DP17_RS07610	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DP17_RS07615	COG2827	Endonuclease containing a URI domain
DP17_RS07620	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DP17_RS07625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP17_RS07625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP17_RS07630	COG0084	hydrolase, TatD family'
DP17_RS07635	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DP17_RS07640	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DP17_RS07645	COG4466	Protein conserved in bacteria
DP17_RS07650	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DP17_RS07655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DP17_RS07660	COG0251	oxidation-reduction process
DP17_RS07665	COG2088	sporulation resulting in formation of a cellular spore
DP17_RS07670	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DP17_RS07675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DP17_RS07680	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DP17_RS07685	COG0193	aminoacyl-tRNA hydrolase activity
DP17_RS07690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DP17_RS07695	COG2244	polysaccharide biosynthetic process
DP17_RS07700	COG3956	TIGRFAM MazG family protein
DP17_RS07705	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DP17_RS07715	COG1098	S1 RNA binding domain
DP17_RS07720	COG0037	tRNA processing
DP17_RS07725	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DP17_RS07730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DP17_RS07735	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DP17_RS07740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DP17_RS07745	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DP17_RS07750	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DP17_RS07755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DP17_RS07760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DP17_RS07840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DP17_RS07845	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DP17_RS07850	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DP17_RS07860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DP17_RS07865	COG4463	regulation of RNA biosynthetic process
DP17_RS07870	COG3880	PFAM UvrB UvrC protein
DP17_RS07875	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DP17_RS07880	COG0542	response to heat
DP17_RS07885	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DP17_RS07890	COG4956	integral membrane protein (PIN domain superfamily)
DP17_RS07895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DP17_RS07900	COG1045	serine acetyltransferase
DP17_RS07905	COG0215	cysteine-tRNA ligase activity
DP17_RS07910	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DP17_RS07915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP17_RS07920	COG3688	RNA-binding protein containing a PIN domain
DP17_RS07930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DP17_RS07935	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DP17_RS07940	COG0250	Participates in transcription elongation, termination and antitermination
DP17_RS07945	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DP17_RS07950	COG0081	regulation of translation
DP17_RS07955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DP17_RS07960	COG0222	ribosome binding
DP17_RS07965	COG2813	Specifically methylates the guanine in position
DP17_RS07970	COG0085	RNA polymerase activity
DP17_RS07975	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DP17_RS07985	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DP17_RS07995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DP17_RS08000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DP17_RS08005	COG1473	amidohydrolase
DP17_RS08025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DP17_RS08030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DP17_RS08035	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DP17_RS08040	COG1063	alcohol dehydrogenase
DP17_RS08045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DP17_RS08050	COG0546	phosphoglycolate phosphatase activity
DP17_RS08055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DP17_RS08060	COG1028	Short-chain dehydrogenase reductase Sdr
DP17_RS08065	COG1428	Deoxynucleoside kinase
DP17_RS08070	COG1428	Deoxynucleoside kinase
DP17_RS08080	COG0561	phosphatase activity
DP17_RS08085	COG0431	NADPH-dependent FMN reductase
DP17_RS08100	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DP17_RS08110	COG1469	GTP cyclohydrolase I activity
DP17_RS08115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DP17_RS08125	COG0363	glucosamine-6-phosphate deaminase activity
DP17_RS08130	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DP17_RS08135	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DP17_RS08145	COG0318	PFAM AMP-dependent synthetase and ligase
DP17_RS08150	COG0183	Belongs to the thiolase family
DP17_RS08170	COG0351	phosphomethylpyrimidine kinase
DP17_RS08180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DP17_RS08190	COG2363	Small membrane protein
DP17_RS08195	COG0531	amino acid
DP17_RS08215	COG3253	May function as heme-dependent peroxidase
DP17_RS08220	COG0280	phosphate acetyltransferase
DP17_RS08225	COG0095	Lipoate-protein ligase
DP17_RS08245	COG4844	belongs to the
DP17_RS08250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DP17_RS08260	COG0667	Aldo Keto reductase
DP17_RS08270	COG1078	dGTPase activity
DP17_RS08280	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DP17_RS08285	COG1691	(AIR) carboxylase
DP17_RS08290	COG1606	tRNA processing
DP17_RS08295	COG3875	lactate racemase activity
DP17_RS08300	COG1064	alcohol dehydrogenase
DP17_RS08315	COG0018	arginyl-trna synthetase
DP17_RS08320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DP17_RS08330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DP17_RS08335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP17_RS08340	COG0546	phosphoglycolate phosphatase activity
DP17_RS08360	COG0596	Alpha beta hydrolase
DP17_RS08390	COG2111	Na H antiporter
DP17_RS08390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DP17_RS08395	COG2111	Na H antiporter
DP17_RS08400	COG1006	Multisubunit Na H antiporter MnhC subunit
DP17_RS08405	COG0651	ATP synthesis coupled electron transport
DP17_RS08410	COG1863	multisubunit Na H antiporter MnhE subunit
DP17_RS08415	COG2212	antiporter activity
DP17_RS08420	COG1320	monovalent cation:proton antiporter activity
DP17_RS08430	COG0803	Belongs to the bacterial solute-binding protein 9 family
DP17_RS08435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DP17_RS08440	COG1121	(ABC) transporter
DP17_RS08445	COG1321	iron dependent repressor
DP17_RS08455	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DP17_RS08460	COG1134	teichoic acid transport
DP17_RS08465	COG1682	transport, permease protein
DP17_RS08470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DP17_RS08480	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DP17_RS08485	COG1132	(ABC) transporter
DP17_RS08490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DP17_RS08495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DP17_RS08500	COG1120	ATPase activity
DP17_RS08510	COG3949	Membrane
DP17_RS08525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DP17_RS08530	COG0745	RESPONSE REGULATOR receiver
DP17_RS08535	COG2205	protein histidine kinase activity
DP17_RS08540	COG1136	(ABC) transporter
DP17_RS08545	COG0577	efflux transmembrane transporter activity
DP17_RS08550	COG1392	Phosphate transport regulator
DP17_RS08555	COG0306	phosphate transporter
DP17_RS08560	COG1388	LysM domain
DP17_RS08560	COG3942	CHAP domain
DP17_RS08580	COG0217	transcriptional regulatory protein
DP17_RS08590	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DP17_RS08610	COG0583	DNA-binding transcription factor activity
DP17_RS08615	COG2814	Major facilitator Superfamily
DP17_RS08620	COG2839	Protein conserved in bacteria
DP17_RS08645	COG1611	Belongs to the LOG family
DP17_RS08650	COG1671	Belongs to the UPF0178 family
DP17_RS08665	COG1968	undecaprenyl-diphosphatase activity
DP17_RS08670	COG4988	ABC transporter
DP17_RS08675	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DP17_RS08695	COG0039	L-malate dehydrogenase activity
DP17_RS08700	COG0471	metal ion transport
DP17_RS08705	COG0415	Belongs to the DNA photolyase family
DP17_RS08730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DP17_RS08735	COG1349	DNA-binding transcription factor activity
DP17_RS08740	COG1105	Belongs to the carbohydrate kinase PfkB family
DP17_RS08745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DP17_RS08745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DP17_RS08745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP17_RS08750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DP17_RS08755	COG1253	flavin adenine dinucleotide binding
DP17_RS08760	COG0656	L-ascorbic acid biosynthetic process
DP17_RS08765	COG0463	Glycosyl transferase, family 2
DP17_RS08770	COG5002	protein histidine kinase activity
DP17_RS08775	COG0745	RESPONSE REGULATOR receiver
DP17_RS08800	COG0602	queuosine metabolic process
DP17_RS08805	COG0720	synthase
DP17_RS08810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DP17_RS08820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DP17_RS08835	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DP17_RS08845	COG1368	sulfuric ester hydrolase activity
DP17_RS08860	COG0488	(ABC) transporter
DP17_RS08865	COG0514	ATP-dependent DNA helicase (RecQ)
DP17_RS08875	COG1174	glycine betaine transport
DP17_RS08880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DP17_RS08885	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
DP17_RS08890	COG1012	belongs to the aldehyde dehydrogenase family
DP17_RS08890	COG1454	alcohol dehydrogenase
DP17_RS08895	COG1597	lipid kinase activity
DP17_RS08905	COG3104	oligopeptide transport
DP17_RS08910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DP17_RS08920	COG1780	Probably involved in ribonucleotide reductase function
DP17_RS08925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DP17_RS08930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DP17_RS08940	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DP17_RS08945	COG4605	iron ion homeostasis
DP17_RS08950	COG4604	ABC transporter, ATP-binding protein
DP17_RS08965	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DP17_RS08985	COG1929	Belongs to the glycerate kinase type-1 family
DP17_RS08990	COG2195	Cleaves the N-terminal amino acid of tripeptides
DP17_RS09005	COG2199	diguanylate cyclase activity
DP17_RS09010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DP17_RS09015	COG1739	Uncharacterized protein family UPF0029
DP17_RS09025	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DP17_RS09030	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DP17_RS09035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DP17_RS09040	COG0653	protein targeting
DP17_RS09045	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DP17_RS09050	COG1388	LysM domain
DP17_RS09050	COG3942	CHAP domain
DP17_RS09065	COG0556	nucleotide-excision repair
DP17_RS09070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DP17_RS09075	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DP17_RS09080	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DP17_RS09095	COG0492	ferredoxin-NADP+ reductase activity
DP17_RS09100	COG1660	Displays ATPase and GTPase activities
DP17_RS09105	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DP17_RS09110	COG1481	regulation of sporulation
DP17_RS09120	COG0740	serine-type endopeptidase activity
DP17_RS09130	COG1090	epimerase
DP17_RS09150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DP17_RS09155	COG0126	phosphoglycerate kinase activity
DP17_RS09160	COG0149	triose-phosphate isomerase activity
DP17_RS09165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DP17_RS09170	COG0148	phosphopyruvate hydratase activity
DP17_RS09180	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DP17_RS09185	COG1647	Serine aminopeptidase, S33
DP17_RS09190	COG0557	exoribonuclease II activity
DP17_RS09195	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DP17_RS09225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DP17_RS09250	COG1278	Cold shock
DP17_RS09265	COG4195	phage-related replication protein
DP17_RS09305	COG1764	response to oxidative stress
DP17_RS09310	COG0710	3-dehydroquinate dehydratase activity
DP17_RS09320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DP17_RS09325	COG1393	Belongs to the ArsC family
DP17_RS09330	COG0509	glycine decarboxylation via glycine cleavage system
DP17_RS09335	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DP17_RS09345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DP17_RS09350	COG2011	ABC-type metal ion transport system permease component
DP17_RS09355	COG1464	Belongs to the NlpA lipoprotein family
DP17_RS09365	COG3237	CsbD-like
DP17_RS09375	COG0396	ATPase activity
DP17_RS09380	COG0719	Fe-S assembly protein
DP17_RS09385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DP17_RS09390	COG0822	iron-sulfur transferase activity
DP17_RS09395	COG0719	Fe-S assembly protein
DP17_RS09410	COG1253	flavin adenine dinucleotide binding
DP17_RS09415	COG1801	Protein of unknown function DUF72
DP17_RS09420	COG0730	response to heat
DP17_RS09425	COG0737	Belongs to the 5'-nucleotidase family
DP17_RS09430	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DP17_RS09435	COG4470	Protein conserved in bacteria
DP17_RS09445	COG2445	Protein of unknown function DUF86
DP17_RS09450	COG0647	UMP catabolic process
DP17_RS09455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DP17_RS09465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DP17_RS09470	COG1696	Membrane protein involved in D-alanine export
DP17_RS09475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DP17_RS09480	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DP17_RS09485	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DP17_RS09490	COG4837	Protein of unknown function (DUF1462)
DP17_RS09495	COG1252	NADH dehydrogenase
DP17_RS09500	COG4844	belongs to the
DP17_RS09505	COG0316	Belongs to the HesB IscA family
DP17_RS09510	COG1252	NADH dehydrogenase
DP17_RS09515	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DP17_RS09520	COG2056	Na+-H+ antiporter family
DP17_RS09525	COG2050	protein possibly involved in aromatic compounds catabolism
DP17_RS09535	COG1320	monovalent cation:proton antiporter activity
DP17_RS09540	COG2212	antiporter activity
DP17_RS09545	COG1863	multisubunit Na H antiporter MnhE subunit
DP17_RS09550	COG0651	ATP synthesis coupled electron transport
DP17_RS09555	COG1006	Multisubunit Na H antiporter MnhC subunit
DP17_RS09560	COG2111	Na H antiporter
DP17_RS09565	COG2111	Na H antiporter
DP17_RS09565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DP17_RS09575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DP17_RS09580	COG1098	S1 RNA binding domain
DP17_RS09585	COG1902	pentaerythritol trinitrate reductase activity
DP17_RS09610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DP17_RS09620	COG0584	glycerophosphoryl diester phosphodiesterase
DP17_RS09625	COG0165	Argininosuccinate lyase
DP17_RS09630	COG0137	argininosuccinate synthase activity
DP17_RS09635	COG0166	Belongs to the GPI family
DP17_RS09640	COG0398	Pfam SNARE associated Golgi protein
DP17_RS09655	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DP17_RS09660	COG1074	ATP-dependent DNA helicase activity
DP17_RS09665	COG0179	Fumarylacetoacetate (FAA) hydrolase
DP17_RS09685	COG0446	pyridine nucleotide-disulphide oxidoreductase
DP17_RS09690	COG0561	phosphatase activity
DP17_RS09705	COG0542	response to heat
DP17_RS09725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DP17_RS09740	COG0601	transmembrane transport
DP17_RS09745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DP17_RS09750	COG0444	Belongs to the ABC transporter superfamily
DP17_RS09755	COG4608	Belongs to the ABC transporter superfamily
DP17_RS09760	COG4166	transmembrane transport
DP17_RS09765	COG0180	Tryptophanyl-tRNA synthetase
DP17_RS09770	COG1393	Belongs to the ArsC family
DP17_RS09775	COG4862	establishment of competence for transformation
DP17_RS09785	COG1164	Oligoendopeptidase f
DP17_RS09790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DP17_RS09795	COG2346	COG2346, Truncated hemoglobins
DP17_RS09810	COG2357	RelA SpoT domain protein
DP17_RS09815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DP17_RS09820	COG0564	pseudouridine synthase activity
DP17_RS09825	COG2239	Acts as a magnesium transporter
DP17_RS09830	COG0475	glutathione-regulated potassium exporter activity
DP17_RS09830	COG0569	domain protein
DP17_RS09885	COG0628	permease
DP17_RS09890	COG2382	esterase
DP17_RS09895	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DP17_RS09900	COG2814	Major facilitator Superfamily
DP17_RS09905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DP17_RS09910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DP17_RS09920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DP17_RS09925	COG0861	Integral membrane protein TerC family
DP17_RS09930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DP17_RS09935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DP17_RS09940	COG0737	Belongs to the 5'-nucleotidase family
DP17_RS09950	COG4873	Protein conserved in bacteria
DP17_RS10095	COG1595	DNA-templated transcription, initiation
DP17_RS10195	COG4824	toxin secretion phage lysis holin
DP17_RS10270	COG2314	TM2 domain
DP17_RS10275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DP17_RS10280	COG1575	Belongs to the MenA family. Type 1 subfamily
DP17_RS10285	COG1169	isochorismate synthase
DP17_RS10290	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DP17_RS10300	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DP17_RS10305	COG0436	Aminotransferase
DP17_RS10310	COG3594	Acyltransferase
DP17_RS10335	COG1316	TRANSCRIPTIONal
DP17_RS10350	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DP17_RS10355	COG1845	cytochrome c oxidase, subunit III
DP17_RS10360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DP17_RS10365	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DP17_RS10375	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DP17_RS10380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DP17_RS10385	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DP17_RS10390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DP17_RS10395	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DP17_RS10400	COG0047	phosphoribosylformylglycinamidine synthase activity
DP17_RS10405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DP17_RS10410	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DP17_RS10415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DP17_RS10420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DP17_RS10425	COG0138	bifunctional purine biosynthesis protein purh
DP17_RS10430	COG0151	Belongs to the GarS family
DP17_RS10435	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DP17_RS10440	COG4172	Belongs to the ABC transporter superfamily
DP17_RS10450	COG4716	Myosin-crossreactive antigen
DP17_RS10465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DP17_RS10475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DP17_RS10480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DP17_RS10495	COG1271	oxidase subunit
DP17_RS10500	COG1294	oxidase, subunit
DP17_RS10505	COG0569	domain protein
DP17_RS10510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DP17_RS10515	COG5503	Protein of unknown function (DUF1447)
DP17_RS10520	COG0242	peptide deformylase activity
DP17_RS10530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DP17_RS10535	COG0022	dehydrogenase e1 component
DP17_RS10540	COG0508	dehydrogenase complex catalyzes the overall conversion of
DP17_RS10550	COG4476	Belongs to the UPF0223 family
DP17_RS10560	COG3842	ATPase activity
DP17_RS10565	COG1176	ABC-type spermidine putrescine transport system, permease component I
DP17_RS10590	COG1914	H( )-stimulated, divalent metal cation uptake system
DP17_RS10595	COG4493	Belongs to the UPF0637 family
DP17_RS10600	COG0483	inositol monophosphate 1-phosphatase activity
DP17_RS10610	COG1217	gtp-binding protein TYPA
DP17_RS10625	COG4896	Protein conserved in bacteria
DP17_RS10630	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DP17_RS10635	COG4838	Belongs to the UPF0358 family
DP17_RS10640	COG0772	Belongs to the SEDS family
DP17_RS10650	COG1612	heme a metabolic process
DP17_RS10655	COG0109	protoheme IX farnesyltransferase activity
DP17_RS10665	COG2340	Cysteine-rich secretory protein family
DP17_RS10670	COG3679	Belongs to the UPF0342 family
DP17_RS10675	COG0584	glycerophosphoryl diester phosphodiesterase
DP17_RS10680	COG4471	UPF0298 protein
DP17_RS10690	COG0742	ribosomal rna small subunit methyltransferase
DP17_RS10695	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DP17_RS10700	COG1323	Belongs to the UPF0348 family
DP17_RS10710	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DP17_RS10720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DP17_RS10725	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DP17_RS10730	COG0072	phenylalanine-tRNA ligase activity
DP17_RS10730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DP17_RS10735	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DP17_RS10740	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DP17_RS10750	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DP17_RS10750	COG1796	DNA polymerase
DP17_RS10755	COG1193	negative regulation of DNA recombination
DP17_RS10760	COG3118	belongs to the thioredoxin family
DP17_RS10765	COG0322	excinuclease ABC activity
DP17_RS10775	COG2009	succinate dehydrogenase
DP17_RS10780	COG1053	succinate dehydrogenase
DP17_RS10785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DP17_RS10790	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DP17_RS10795	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DP17_RS10825	COG1011	Hydrolase
DP17_RS10830	COG0454	-acetyltransferase
DP17_RS10835	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DP17_RS10840	COG2001	Belongs to the MraZ family
DP17_RS10845	COG0275	rRNA processing
DP17_RS10850	COG4839	cell division protein FtsL
DP17_RS10855	COG0768	penicillin binding
DP17_RS10860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DP17_RS10865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DP17_RS10870	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DP17_RS10875	COG0849	cell division
DP17_RS10880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DP17_RS10885	COG1496	oxidoreductase activity
DP17_RS10890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DP17_RS10895	COG1799	cell septum assembly
DP17_RS10900	COG0762	integral membrane protein
DP17_RS10910	COG3599	regulation of cell shape
DP17_RS10915	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DP17_RS10925	COG3942	CHAP domain
DP17_RS10925	COG1388	LysM domain
DP17_RS10930	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DP17_RS10935	COG0564	pseudouridine synthase activity
DP17_RS10940	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DP17_RS10945	COG2233	PERMEase
DP17_RS10950	COG0540	Belongs to the ATCase OTCase family
DP17_RS10955	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DP17_RS10960	COG0505	Belongs to the CarA family
DP17_RS10965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DP17_RS10970	COG0284	orotidine-5'-phosphate decarboxylase activity
DP17_RS10975	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DP17_RS11000	COG0194	GDP metabolic process
DP17_RS11005	COG1758	RNA polymerase activity
DP17_RS11010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DP17_RS11015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DP17_RS11025	COG0242	peptide deformylase activity
DP17_RS11030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DP17_RS11035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DP17_RS11035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DP17_RS11040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DP17_RS11045	COG0631	protein serine/threonine phosphatase activity
DP17_RS11055	COG1162	GTPase activity
DP17_RS11060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DP17_RS11070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DP17_RS11075	COG1302	Protein conserved in bacteria
DP17_RS11080	COG1461	Dihydroxyacetone kinase
DP17_RS11085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DP17_RS11090	COG1349	DNA-binding transcription factor activity
DP17_RS11095	COG0416	fatty acid biosynthetic process
DP17_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
DP17_RS11110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DP17_RS11115	COG0571	ribonuclease III activity
DP17_RS11120	COG1196	nuclear chromosome segregation
DP17_RS11125	COG0552	protein localization to endoplasmic reticulum
DP17_RS11130	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DP17_RS11135	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DP17_RS11140	COG0228	four-way junction DNA binding
DP17_RS11145	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DP17_RS11150	COG0336	Belongs to the RNA methyltransferase TrmD family
DP17_RS11155	COG0335	large ribosomal subunit rRNA binding
DP17_RS11175	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DP17_RS11180	COG0045	succinate-CoA ligase (ADP-forming) activity
DP17_RS11185	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DP17_RS11190	COG0758	DNA mediated transformation
DP17_RS11195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DP17_RS11200	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DP17_RS11205	COG4974	Belongs to the 'phage' integrase family
DP17_RS11210	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DP17_RS11215	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DP17_RS11220	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DP17_RS11225	COG0052	Belongs to the universal ribosomal protein uS2 family
DP17_RS11230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DP17_RS11235	COG0528	UMP kinase activity
DP17_RS11240	COG0233	cytoplasmic translational termination
DP17_RS11245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DP17_RS11250	COG4589	Belongs to the CDS family
DP17_RS11260	COG0442	prolyl-tRNA aminoacylation
DP17_RS11265	COG2176	DNA-directed DNA polymerase activity
DP17_RS11270	COG0779	Required for maturation of 30S ribosomal subunits
DP17_RS11275	COG0195	Participates in both transcription termination and antitermination
DP17_RS11280	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DP17_RS11285	COG1358	cellular component organization or biogenesis
DP17_RS11290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DP17_RS11295	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DP17_RS11300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DP17_RS11305	COG0196	riboflavin kinase activity
DP17_RS11310	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DP17_RS11315	COG1185	polyribonucleotide nucleotidyltransferase activity
DP17_RS11320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DP17_RS11325	COG1674	ftsk spoiiie
DP17_RS11330	COG2188	Transcriptional regulator
DP17_RS11335	COG0612	Peptidase, M16
DP17_RS11340	COG0612	Peptidase, M16
DP17_RS11345	COG0300	oxidoreductase activity
DP17_RS11360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DP17_RS11370	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DP17_RS11375	COG1418	mRNA catabolic process
DP17_RS11385	COG1692	metallophosphoesterase
DP17_RS11390	COG0674	pyruvate-flavodoxin oxidoreductase activity
DP17_RS11390	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DP17_RS11395	COG1013	pyruvate-flavodoxin oxidoreductase activity
DP17_RS11400	COG4195	phage-related replication protein
DP17_RS11410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DP17_RS11415	COG4550	Control of competence regulator ComK, YlbF/YmcA
DP17_RS11425	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DP17_RS11430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DP17_RS11435	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DP17_RS11440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DP17_RS11445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DP17_RS11450	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DP17_RS11455	COG2267	carboxylic ester hydrolase activity
DP17_RS11460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DP17_RS11465	COG1923	regulation of RNA biosynthetic process
DP17_RS11470	COG0386	Belongs to the glutathione peroxidase family
DP17_RS11475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DP17_RS11480	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DP17_RS11485	COG0789	Transcriptional regulator
DP17_RS11490	COG0174	glutamine synthetase
DP17_RS11530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DP17_RS11535	COG1131	(ABC) transporter
DP17_RS11545	COG4585	Histidine kinase
DP17_RS11550	COG2197	response regulator
DP17_RS11560	COG1525	nuclease
DP17_RS11580	COG0527	aspartate kinase activity
DP17_RS11585	COG0460	homoserine dehydrogenase
DP17_RS11590	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DP17_RS11595	COG0083	homoserine kinase activity
DP17_RS11610	COG0833	amino acid
DP17_RS11615	COG0753	catalase activity
DP17_RS11625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DP17_RS11630	COG0516	GMP reductase activity
DP17_RS11635	COG2340	Cysteine-rich secretory protein family
DP17_RS11640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DP17_RS11650	COG4224	UPF0291 protein
DP17_RS11655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DP17_RS11665	COG4846	Membrane protein involved in cytochrome C biogenesis
DP17_RS11670	COG0420	3'-5' exonuclease activity
DP17_RS11675	COG0419	ATPase involved in DNA repair
DP17_RS11680	COG1970	mechanosensitive ion channel activity
DP17_RS11685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DP17_RS11690	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DP17_RS11695	COG0824	Thioesterase
DP17_RS11700	COG4841	protein insertion into membrane
DP17_RS11705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DP17_RS11710	COG0187	DNA topoisomerase II activity
DP17_RS11715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DP17_RS11720	COG1115	amino acid carrier protein
DP17_RS11725	COG3711	transcriptional antiterminator
DP17_RS11730	COG0628	permease
DP17_RS11735	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DP17_RS11735	COG0392	lysyltransferase activity
DP17_RS11750	COG1942	4-Oxalocrotonate Tautomerase
DP17_RS11760	COG0287	Prephenate dehydrogenase
DP17_RS11800	COG0135	phosphoribosylanthranilate isomerase activity
DP17_RS11950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate