locus-tag	class	description
MNU43_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MNU43_RS00010	COG0592	DNA-directed DNA polymerase activity
MNU43_RS00015	COG2501	S4 domain
MNU43_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MNU43_RS00025	COG0187	DNA topoisomerase II activity
MNU43_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MNU43_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MNU43_RS00040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MNU43_RS00060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MNU43_RS00070	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MNU43_RS00075	COG0359	binds to the 23S rRNA
MNU43_RS00080	COG0305	Participates in initiation and elongation during chromosome replication
MNU43_RS00085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MNU43_RS00100	COG0745	RESPONSE REGULATOR receiver
MNU43_RS00105	COG5002	protein histidine kinase activity
MNU43_RS00110	COG4863	YycH protein
MNU43_RS00120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MNU43_RS00125	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MNU43_RS00145	COG3425	synthase
MNU43_RS00150	COG0584	glycerophosphoryl diester phosphodiesterase
MNU43_RS00155	COG2030	dehydratase
MNU43_RS00280	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MNU43_RS00315	COG0745	RESPONSE REGULATOR receiver
MNU43_RS00320	COG2205	protein histidine kinase activity
MNU43_RS00330	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MNU43_RS00335	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MNU43_RS00365	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MNU43_RS00370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MNU43_RS00380	COG2235	arginine
MNU43_RS00415	COG4172	Belongs to the ABC transporter superfamily
MNU43_RS00420	COG1124	(ABC) transporter
MNU43_RS00480	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MNU43_RS00485	COG1353	crispr-associated protein
MNU43_RS00490	COG1421	Csm2 Type III-A
MNU43_RS00495	COG1337	RAMP superfamily
MNU43_RS00500	COG1567	CRISPR-associated RAMP protein, Csm4 family
MNU43_RS00505	COG1332	CRISPR-associated RAMP protein, Csm5 family
MNU43_RS00530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MNU43_RS00535	COG1131	(ABC) transporter
MNU43_RS00550	COG0745	RESPONSE REGULATOR receiver
MNU43_RS00555	COG5002	protein histidine kinase activity
MNU43_RS00575	COG2217	Heavy metal translocating P-type atpase
MNU43_RS00580	COG1388	LysM domain
MNU43_RS00585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MNU43_RS00590	COG2210	Belongs to the sulfur carrier protein TusA family
MNU43_RS00595	COG1937	Protein conserved in bacteria
MNU43_RS00600	COG0730	response to heat
MNU43_RS00605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNU43_RS00610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MNU43_RS00630	COG0640	Transcriptional regulator
MNU43_RS00645	COG0668	transmembrane transport
MNU43_RS00650	COG0561	phosphatase activity
MNU43_RS00680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MNU43_RS00685	COG0579	oxidoreductase
MNU43_RS00690	COG1028	Short-chain dehydrogenase reductase Sdr
MNU43_RS00700	COG1755	Isoprenylcysteine carboxyl methyltransferase
MNU43_RS00710	COG2207	Transcriptional regulator
MNU43_RS00710	COG4753	response regulator
MNU43_RS00715	COG2972	Histidine kinase
MNU43_RS00740	COG4932	domain protein
MNU43_RS00740	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MNU43_RS00740	COG3583	domain protein
MNU43_RS00750	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MNU43_RS00755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MNU43_RS00760	COG0156	8-amino-7-oxononanoate synthase activity
MNU43_RS00765	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MNU43_RS00795	COG0523	cobalamin synthesis protein
MNU43_RS00820	COG3976	FMN-binding domain protein
MNU43_RS00820	COG1053	succinate dehydrogenase
MNU43_RS00820	COG0431	NADPH-dependent FMN reductase
MNU43_RS00830	COG1028	Short-chain dehydrogenase reductase Sdr
MNU43_RS00835	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MNU43_RS00865	COG0601	transmembrane transport
MNU43_RS00875	COG0444	Belongs to the ABC transporter superfamily
MNU43_RS00880	COG1124	(ABC) transporter
MNU43_RS00890	COG1882	Formate acetyltransferase
MNU43_RS00895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MNU43_RS00900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MNU43_RS00905	COG1114	Component of the transport system for branched-chain amino acids
MNU43_RS00910	COG1309	transcriptional regulator
MNU43_RS00915	COG3246	L-lysine catabolic process to acetate
MNU43_RS00920	COG1250	3-hydroxyacyl-CoA dehydrogenase
MNU43_RS00955	COG1288	antiporter activity
MNU43_RS00960	COG0549	Belongs to the carbamate kinase family
MNU43_RS00965	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MNU43_RS00975	COG0346	lactoylglutathione lyase activity
MNU43_RS00980	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MNU43_RS00985	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MNU43_RS00995	COG2376	Dihydroxyacetone kinase
MNU43_RS01000	COG1461	Dihydroxyacetone kinase
MNU43_RS01005	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
MNU43_RS01020	COG2814	Major facilitator Superfamily
MNU43_RS01050	COG2814	Major facilitator Superfamily
MNU43_RS01065	COG2962	Rard protein
MNU43_RS01070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MNU43_RS01075	COG0471	metal ion transport
MNU43_RS01080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MNU43_RS01085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MNU43_RS01090	COG0022	dehydrogenase e1 component
MNU43_RS01095	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNU43_RS01120	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MNU43_RS01125	COG1054	Belongs to the UPF0176 family
MNU43_RS01130	COG3386	PFAM SMP-30 Gluconolaconase
MNU43_RS01135	COG2353	YceI-like domain
MNU43_RS01140	COG0579	oxidoreductase
MNU43_RS01165	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MNU43_RS01170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MNU43_RS01175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MNU43_RS01180	COG0131	Imidazoleglycerol-phosphate dehydratase
MNU43_RS01185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MNU43_RS01190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MNU43_RS01195	COG0107	imidazoleglycerol-phosphate synthase activity
MNU43_RS01200	COG0140	phosphoribosyl-ATP diphosphatase activity
MNU43_RS01200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MNU43_RS01205	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MNU43_RS01210	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MNU43_RS01225	COG2814	Major facilitator Superfamily
MNU43_RS01230	COG0737	Belongs to the 5'-nucleotidase family
MNU43_RS01245	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MNU43_RS01250	COG3639	organic phosphonate transmembrane transporter activity
MNU43_RS01270	COG0201	protein transport
MNU43_RS01280	COG1073	alpha beta
MNU43_RS01290	COG0653	protein targeting
MNU43_RS01295	COG0438	transferase activity, transferring glycosyl groups
MNU43_RS01320	COG2814	Major facilitator Superfamily
MNU43_RS01325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MNU43_RS01340	COG1764	response to oxidative stress
MNU43_RS01350	COG1705	Flagellar rod assembly protein muramidase FlgJ
MNU43_RS01350	COG3942	CHAP domain
MNU43_RS01360	COG1482	cell wall glycoprotein biosynthetic process
MNU43_RS01365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MNU43_RS01365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MNU43_RS01365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MNU43_RS01370	COG3711	transcriptional antiterminator
MNU43_RS01370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MNU43_RS01405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MNU43_RS01410	COG3227	Zinc metalloprotease (Elastase)
MNU43_RS01415	COG1438	arginine binding
MNU43_RS01425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MNU43_RS01435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MNU43_RS01445	COG2843	Capsule synthesis protein
MNU43_RS01450	COG3961	Belongs to the TPP enzyme family
MNU43_RS01485	COG0659	secondary active sulfate transmembrane transporter activity
MNU43_RS01510	COG0583	DNA-binding transcription factor activity
MNU43_RS01555	COG0640	Transcriptional regulator
MNU43_RS01590	COG1397	ADP-ribosylglycohydrolase
MNU43_RS01615	COG4195	phage-related replication protein
MNU43_RS01625	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MNU43_RS01630	COG0702	epimerase
MNU43_RS01635	COG1785	Belongs to the alkaline phosphatase family
MNU43_RS01650	COG2205	protein histidine kinase activity
MNU43_RS01655	COG1136	(ABC) transporter
MNU43_RS01670	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MNU43_RS01695	COG1846	Transcriptional regulator
MNU43_RS01705	COG0386	Belongs to the glutathione peroxidase family
MNU43_RS01710	COG0175	sulfate reduction
MNU43_RS01715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MNU43_RS01720	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MNU43_RS01735	COG0730	response to heat
MNU43_RS01740	COG2046	Belongs to the sulfate adenylyltransferase family
MNU43_RS01745	COG0529	Catalyzes the synthesis of activated sulfate
MNU43_RS01755	COG1328	CTP reductase activity
MNU43_RS01760	COG0602	queuosine metabolic process
MNU43_RS01765	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MNU43_RS01775	COG1510	regulation of RNA biosynthetic process
MNU43_RS01780	COG1012	belongs to the aldehyde dehydrogenase family
MNU43_RS01785	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MNU43_RS01790	COG1473	amidohydrolase
MNU43_RS01805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MNU43_RS01810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MNU43_RS01810	COG0574	Belongs to the PEP-utilizing enzyme family
MNU43_RS01815	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MNU43_RS01820	COG0579	oxidoreductase
MNU43_RS01830	COG3588	fructose-bisphosphate aldolase
MNU43_RS01835	COG0446	pyridine nucleotide-disulphide oxidoreductase
MNU43_RS01865	COG0531	amino acid
MNU43_RS01870	COG0583	DNA-binding transcription factor activity
MNU43_RS01875	COG0039	L-malate dehydrogenase activity
MNU43_RS01880	COG0028	Belongs to the TPP enzyme family
MNU43_RS01885	COG3527	Alpha-acetolactate decarboxylase
MNU43_RS01895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MNU43_RS01900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MNU43_RS01905	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MNU43_RS01920	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MNU43_RS01940	COG0167	dihydroorotate dehydrogenase activity
MNU43_RS01945	COG3001	Fructosamine kinase
MNU43_RS01950	COG1113	amino acid transport
MNU43_RS01965	COG0741	lytic transglycosylase activity
MNU43_RS01975	COG3942	CHAP domain
MNU43_RS01980	COG0436	Aminotransferase
MNU43_RS01990	COG2608	mercury ion transmembrane transporter activity
MNU43_RS01995	COG2217	Heavy metal translocating P-type atpase
MNU43_RS02005	COG1028	Short-chain dehydrogenase reductase Sdr
MNU43_RS02010	COG1012	belongs to the aldehyde dehydrogenase family
MNU43_RS02035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MNU43_RS02040	COG3425	synthase
MNU43_RS02060	COG0583	DNA-binding transcription factor activity
MNU43_RS02065	COG1380	Effector of murein hydrolase LrgA
MNU43_RS02070	COG1346	cytolysis
MNU43_RS02075	COG0028	Belongs to the TPP enzyme family
MNU43_RS02080	COG1263	PTS System
MNU43_RS02080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MNU43_RS02080	COG2190	(PTS) system
MNU43_RS02095	COG1063	alcohol dehydrogenase
MNU43_RS02105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MNU43_RS02120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MNU43_RS02130	COG2843	Capsule synthesis protein
MNU43_RS02145	COG4975	Glucose uptake
MNU43_RS02150	COG1869	D-ribose catabolic process
MNU43_RS02160	COG1070	Carbohydrate kinase
MNU43_RS02175	COG1760	l-serine dehydratase
MNU43_RS02180	COG1760	l-serine dehydratase
MNU43_RS02205	COG3764	Sortase (surface protein transpeptidase)
MNU43_RS02215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNU43_RS02220	COG0778	Nitroreductase
MNU43_RS02225	COG1012	belongs to the aldehyde dehydrogenase family
MNU43_RS02235	COG2514	catechol 2,3-dioxygenase activity
MNU43_RS02250	COG1012	belongs to the aldehyde dehydrogenase family
MNU43_RS02255	COG3949	Membrane
MNU43_RS02265	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
MNU43_RS02270	COG0586	Pfam SNARE associated Golgi protein
MNU43_RS02275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MNU43_RS02280	COG2022	thiamine diphosphate biosynthetic process
MNU43_RS02290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MNU43_RS02300	COG2271	Major facilitator Superfamily
MNU43_RS02315	COG4876	unkown
MNU43_RS02320	COG2357	RelA SpoT domain protein
MNU43_RS02335	COG0789	Transcriptional regulator
MNU43_RS02340	COG2271	Major facilitator Superfamily
MNU43_RS02345	COG1802	Transcriptional regulator
MNU43_RS02355	COG2610	gluconate transmembrane transporter activity
MNU43_RS02360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MNU43_RS02365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MNU43_RS02370	COG0438	transferase activity, transferring glycosyl groups
MNU43_RS02375	COG0494	nUDIX hydrolase
MNU43_RS02380	COG0556	nucleotide-excision repair
MNU43_RS02395	COG4221	oxidoreductase activity
MNU43_RS02400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MNU43_RS02405	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MNU43_RS02415	COG1028	Short-chain dehydrogenase reductase Sdr
MNU43_RS02425	COG1363	Peptidase, m42
MNU43_RS02435	COG0069	glutamate synthase activity
MNU43_RS02450	COG4619	ABC transporter
MNU43_RS02455	COG0390	transport system, permease component
MNU43_RS02460	COG2814	Major facilitator Superfamily
MNU43_RS02465	COG2272	Belongs to the type-B carboxylesterase lipase family
MNU43_RS02470	COG0531	amino acid
MNU43_RS02480	COG1063	alcohol dehydrogenase
MNU43_RS02500	COG1174	glycine betaine transport
MNU43_RS02505	COG1346	cytolysis
MNU43_RS02510	COG1380	Effector of murein hydrolase LrgA
MNU43_RS02515	COG3279	Response regulator of the LytR AlgR family
MNU43_RS02520	COG3275	phosphorelay sensor kinase activity
MNU43_RS02530	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MNU43_RS02535	COG0706	membrane insertase activity
MNU43_RS02545	COG0531	amino acid
MNU43_RS02550	COG1113	amino acid transport
MNU43_RS02575	COG1929	Belongs to the glycerate kinase type-1 family
MNU43_RS02590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MNU43_RS02595	COG0588	phosphoglycerate mutase activity
MNU43_RS02605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MNU43_RS02610	COG0765	amino acid transport
MNU43_RS02615	COG1126	abc transporter atp-binding protein
MNU43_RS02625	COG2348	transferase activity, transferring amino-acyl groups
MNU43_RS02645	COG2116	formate transmembrane transporter activity
MNU43_RS02650	COG0454	-acetyltransferase
MNU43_RS02660	COG0747	negative chemotaxis
MNU43_RS02670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MNU43_RS02675	COG2146	nitrite reductase [NAD(P)H] activity
MNU43_RS02685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MNU43_RS02690	COG1140	nitrate reductase beta subunit
MNU43_RS02700	COG2181	nitrate reductase activity
MNU43_RS02710	COG4585	Histidine kinase
MNU43_RS02715	COG2197	response regulator
MNU43_RS02720	COG2223	nitrite transmembrane transporter activity
MNU43_RS02725	COG1846	Transcriptional regulator
MNU43_RS02730	COG0778	Nitroreductase
MNU43_RS02750	COG3871	stress protein (general stress protein 26)
MNU43_RS02765	COG1263	PTS System
MNU43_RS02765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MNU43_RS02810	COG0604	alcohol dehydrogenase
MNU43_RS02815	COG0456	acetyltransferase
MNU43_RS02820	COG0463	Glycosyl transferase, family 2
MNU43_RS02820	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MNU43_RS02830	COG0463	Glycosyl transferase, family 2
MNU43_RS02830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MNU43_RS02835	COG1620	l-lactate permease
MNU43_RS02840	COG0438	transferase activity, transferring glycosyl groups
MNU43_RS02845	COG0579	oxidoreductase
MNU43_RS02850	COG5002	protein histidine kinase activity
MNU43_RS02850	COG3850	Histidine kinase
MNU43_RS02855	COG0745	RESPONSE REGULATOR receiver
MNU43_RS02860	COG0577	efflux transmembrane transporter activity
MNU43_RS02865	COG1136	(ABC) transporter
MNU43_RS02880	COG4640	response to antibiotic
MNU43_RS02885	COG2814	Major facilitator Superfamily
MNU43_RS02895	COG1566	PFAM secretion protein HlyD family protein
MNU43_RS02900	COG2814	Major facilitator Superfamily
MNU43_RS02910	COG0657	acetylesterase activity
MNU43_RS02925	COG0598	Magnesium transport protein CorA
MNU43_RS02930	COG1304	FMN binding
MNU43_RS02935	COG0786	glutamate:sodium symporter activity
MNU43_RS02955	COG2094	Belongs to the DNA glycosylase MPG family
MNU43_RS02965	COG1069	ribulokinase activity
MNU43_RS02970	COG2017	converts alpha-aldose to the beta-anomer
MNU43_RS02975	COG2258	MOSC domain
MNU43_RS02980	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MNU43_RS02990	COG1266	CAAX protease self-immunity
MNU43_RS02995	COG0010	Belongs to the arginase family
MNU43_RS03000	COG1473	amidohydrolase
MNU43_RS03005	COG1028	Short-chain dehydrogenase reductase Sdr
MNU43_RS03010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MNU43_RS03040	COG1737	Transcriptional regulator
MNU43_RS03045	COG1263	PTS System
MNU43_RS03045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MNU43_RS03055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MNU43_RS03080	COG1113	amino acid transport
MNU43_RS03090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MNU43_RS03090	COG1263	PTS System
MNU43_RS03095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MNU43_RS03110	COG1266	CAAX protease self-immunity
MNU43_RS03115	COG2378	regulation of single-species biofilm formation
MNU43_RS03120	COG0483	inositol monophosphate 1-phosphatase activity
MNU43_RS03125	COG1316	TRANSCRIPTIONal
MNU43_RS03145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNU43_RS03150	COG2076	Multidrug Resistance protein
MNU43_RS03155	COG2076	Multidrug Resistance protein
MNU43_RS03160	COG3942	CHAP domain
MNU43_RS03175	COG1757	Na H antiporter
MNU43_RS03180	COG3942	CHAP domain
MNU43_RS03205	COG0829	nickel cation binding
MNU43_RS03210	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MNU43_RS03215	COG0830	nickel cation binding
MNU43_RS03220	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MNU43_RS03225	COG0804	urea catabolic process
MNU43_RS03230	COG0832	Belongs to the urease beta subunit family
MNU43_RS03235	COG0831	urea catabolic process
MNU43_RS03245	COG1960	acyl-CoA dehydrogenase activity
MNU43_RS03250	COG1957	nucleoside hydrolase
MNU43_RS03255	COG1268	BioY protein
MNU43_RS03270	COG0725	ABC transporter, periplasmic molybdate-binding protein
MNU43_RS03275	COG4149	molybdate abc transporter
MNU43_RS03280	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MNU43_RS03285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MNU43_RS03290	COG0521	Mo-molybdopterin cofactor biosynthetic process
MNU43_RS03295	COG0315	cyclic pyranopterin monophosphate synthase activity
MNU43_RS03300	COG0303	'Molybdopterin
MNU43_RS03310	COG0314	molybdopterin synthase activity
MNU43_RS03320	COG0746	molybdenum cofactor guanylyltransferase activity
MNU43_RS03325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MNU43_RS03365	COG2348	transferase activity, transferring amino-acyl groups
MNU43_RS03370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MNU43_RS03390	COG1028	Short-chain dehydrogenase reductase Sdr
MNU43_RS03395	COG4975	Glucose uptake
MNU43_RS03400	COG0551	DNA topoisomerase type I activity
MNU43_RS03400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MNU43_RS03405	COG2252	PERMEase
MNU43_RS03420	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MNU43_RS03425	COG0088	Forms part of the polypeptide exit tunnel
MNU43_RS03430	COG0089	rRNA binding
MNU43_RS03435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MNU43_RS03440	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MNU43_RS03445	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MNU43_RS03450	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MNU43_RS03455	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MNU43_RS03465	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MNU43_RS03470	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MNU43_RS03475	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MNU43_RS03480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MNU43_RS03485	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MNU43_RS03490	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MNU43_RS03495	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MNU43_RS03500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MNU43_RS03505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MNU43_RS03510	COG1841	ribosomal large subunit assembly
MNU43_RS03515	COG0200	Binds to the 23S rRNA
MNU43_RS03520	COG0201	protein transport
MNU43_RS03525	COG0563	adenylate kinase activity
MNU43_RS03530	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MNU43_RS03535	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MNU43_RS03540	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MNU43_RS03545	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MNU43_RS03550	COG0202	RNA polymerase activity
MNU43_RS03555	COG0203	ribosomal protein L17
MNU43_RS03560	COG1122	ATPase activity
MNU43_RS03565	COG1122	ATPase activity
MNU43_RS03575	COG0101	tRNA pseudouridine synthase activity
MNU43_RS03580	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MNU43_RS03585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MNU43_RS03590	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MNU43_RS03595	COG1349	DNA-binding transcription factor activity
MNU43_RS03600	COG0698	ribose 5-phosphate isomerase
MNU43_RS03605	COG0698	ribose 5-phosphate isomerase
MNU43_RS03610	COG1105	Belongs to the carbohydrate kinase PfkB family
MNU43_RS03615	COG3684	Belongs to the aldolase LacD family
MNU43_RS03620	COG1447	Phosphotransferase system cellobiose-specific component IIA
MNU43_RS03625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MNU43_RS03625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MNU43_RS03630	COG2723	6-phospho-beta-galactosidase activity
MNU43_RS03640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNU43_RS03645	COG2130	NADP-dependent
MNU43_RS03650	COG0604	alcohol dehydrogenase
MNU43_RS03665	COG1302	Protein conserved in bacteria
MNU43_RS03670	COG4264	IucA IucC family
MNU43_RS03675	COG2814	Major facilitator Superfamily
MNU43_RS03680	COG4264	IucA IucC family
MNU43_RS03685	COG3457	Alanine racemase
MNU43_RS03690	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MNU43_RS03695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MNU43_RS03700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MNU43_RS03705	COG3314	Sporulation integral membrane protein YlbJ
MNU43_RS03710	COG2329	Antibiotic biosynthesis monooxygenase
MNU43_RS03720	COG1988	membrane-bound metal-dependent
MNU43_RS03725	COG4284	Utp--glucose-1-phosphate uridylyltransferase
MNU43_RS03745	COG2814	Major facilitator Superfamily
MNU43_RS03750	COG0489	protein tyrosine kinase activity
MNU43_RS03800	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MNU43_RS03810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MNU43_RS03815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MNU43_RS03820	COG0561	phosphatase activity
MNU43_RS03840	COG0640	Transcriptional regulator
MNU43_RS03845	COG0702	epimerase
MNU43_RS03850	COG1482	cell wall glycoprotein biosynthetic process
MNU43_RS03870	COG0783	Belongs to the Dps family
MNU43_RS03875	COG0813	purine-nucleoside phosphorylase activity
MNU43_RS03880	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MNU43_RS03885	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MNU43_RS03890	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MNU43_RS03900	COG1854	S-ribosylhomocysteine lyase activity
MNU43_RS03920	COG5146	pantothenate kinase activity
MNU43_RS03930	COG3343	RNA polymerase activity
MNU43_RS03935	COG0504	CTP synthase activity
MNU43_RS03945	COG0191	fructose-bisphosphate aldolase activity
MNU43_RS03950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MNU43_RS03955	COG1012	belongs to the aldehyde dehydrogenase family
MNU43_RS03960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MNU43_RS03965	COG0254	rRNA binding
MNU43_RS03970	COG1435	thymidine kinase activity
MNU43_RS03975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MNU43_RS03980	COG2890	protein-(glutamine-N5) methyltransferase activity
MNU43_RS03985	COG0009	L-threonylcarbamoyladenylate synthase
MNU43_RS03990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNU43_RS03995	COG4475	Protein of unknown function (DUF436)
MNU43_RS04000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MNU43_RS04005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MNU43_RS04010	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MNU43_RS04020	COG0356	it plays a direct role in the translocation of protons across the membrane
MNU43_RS04030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MNU43_RS04035	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MNU43_RS04040	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MNU43_RS04045	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MNU43_RS04050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MNU43_RS04055	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MNU43_RS04065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MNU43_RS04070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MNU43_RS04080	COG0629	single-stranded DNA binding
MNU43_RS04085	COG1388	LysM domain
MNU43_RS04090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MNU43_RS04100	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MNU43_RS04105	COG0352	thiamine-phosphate diphosphorylase activity
MNU43_RS04110	COG0706	membrane insertase activity
MNU43_RS04115	COG1418	mRNA catabolic process
MNU43_RS04120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNU43_RS04125	COG1937	Protein conserved in bacteria
MNU43_RS04140	COG0772	Belongs to the SEDS family
MNU43_RS04145	COG1181	Belongs to the D-alanine--D-alanine ligase family
MNU43_RS04150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MNU43_RS04155	COG0513	Belongs to the DEAD box helicase family
MNU43_RS04165	COG3428	Bacterial PH domain
MNU43_RS04170	COG3402	PFAM membrane-flanked domain
MNU43_RS04175	COG0736	holo-[acyl-carrier-protein] synthase activity
MNU43_RS04180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MNU43_RS04190	COG2337	Toxic component of a toxin-antitoxin (TA) module
MNU43_RS04195	COG2208	phosphoserine phosphatase activity
MNU43_RS04210	COG1191	sigma factor activity
MNU43_RS04215	COG2183	response to ionizing radiation
MNU43_RS04220	COG3091	SprT-like family
MNU43_RS04250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MNU43_RS04255	COG0066	3-isopropylmalate dehydratase activity
MNU43_RS04260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MNU43_RS04265	COG0473	3-isopropylmalate dehydrogenase activity
MNU43_RS04270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MNU43_RS04275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MNU43_RS04285	COG0028	Belongs to the TPP enzyme family
MNU43_RS04290	COG0129	dihydroxy-acid dehydratase activity
MNU43_RS04295	COG0802	atpase or kinase
MNU43_RS04300	COG1214	PFAM Peptidase M22, glycoprotease
MNU43_RS04305	COG0456	acetyltransferase
MNU43_RS04310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MNU43_RS04315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MNU43_RS04320	COG0488	(ABC) transporter
MNU43_RS04325	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MNU43_RS04335	COG2391	methyltransferase activity
MNU43_RS04340	COG0425	Belongs to the sulfur carrier protein TusA family
MNU43_RS04345	COG0004	ammonium transporteR
MNU43_RS04350	COG1609	Transcriptional regulator
MNU43_RS04355	COG1621	beta-fructofuranosidase activity
MNU43_RS04360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MNU43_RS04365	COG3279	Response regulator of the LytR AlgR family
MNU43_RS04370	COG3290	protein histidine kinase activity
MNU43_RS04410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MNU43_RS04415	COG0459	protein refolding
MNU43_RS04440	COG1725	Transcriptional regulator
MNU43_RS04445	COG1131	(ABC) transporter
MNU43_RS04455	COG1131	(ABC) transporter
MNU43_RS04505	COG4974	Belongs to the 'phage' integrase family
MNU43_RS04535	COG3682	Transcriptional regulator
MNU43_RS04545	COG2706	6-phosphogluconolactonase activity
MNU43_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
MNU43_RS04555	COG1227	inorganic diphosphatase activity
MNU43_RS04560	COG1335	isochorismatase
MNU43_RS04570	COG0077	Prephenate dehydratase
MNU43_RS04580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MNU43_RS04585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MNU43_RS04590	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MNU43_RS04600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MNU43_RS04605	COG4496	protein, YerC YecD
MNU43_RS04610	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MNU43_RS04615	COG0210	DNA helicase
MNU43_RS04620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MNU43_RS04625	COG4851	CamS sex pheromone cAM373 precursor
MNU43_RS04630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MNU43_RS04635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MNU43_RS04640	COG0154	amidase activity
MNU43_RS04645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MNU43_RS04650	COG1597	lipid kinase activity
MNU43_RS04655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MNU43_RS04665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MNU43_RS04675	COG1528	Iron-storage protein
MNU43_RS04695	COG4129	membrane
MNU43_RS04700	COG0024	Methionine aminopeptidase
MNU43_RS04715	COG4585	Histidine kinase
MNU43_RS04720	COG2197	response regulator
MNU43_RS04725	COG1295	ribonuclease BN
MNU43_RS04735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNU43_RS04740	COG4840	Belongs to the UPF0435 family
MNU43_RS04745	COG2309	aminopeptidase activity
MNU43_RS04750	COG1607	acyl-coa hydrolase
MNU43_RS04755	COG0535	radical SAM domain protein
MNU43_RS04765	COG0693	protein deglycase activity
MNU43_RS04770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MNU43_RS04775	COG2137	regulation of response to DNA damage stimulus
MNU43_RS04785	COG1134	teichoic acid transport
MNU43_RS04785	COG1388	LysM domain
MNU43_RS04795	COG1988	membrane-bound metal-dependent
MNU43_RS04805	COG3557	Belongs to the UPF0374 family
MNU43_RS04815	COG4129	membrane
MNU43_RS04820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MNU43_RS04825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MNU43_RS04830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNU43_RS04835	COG0735	belongs to the Fur family
MNU43_RS05010	COG0765	amino acid transport
MNU43_RS05015	COG1126	abc transporter atp-binding protein
MNU43_RS05025	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MNU43_RS05050	COG0114	fumarate hydratase activity
MNU43_RS05055	COG0564	pseudouridine synthase activity
MNU43_RS05060	COG4585	Histidine kinase
MNU43_RS05060	COG2203	Gaf domain
MNU43_RS05065	COG2197	response regulator
MNU43_RS05075	COG4399	Belongs to the UPF0754 family
MNU43_RS05080	COG3679	Belongs to the UPF0342 family
MNU43_RS05085	COG0420	3'-5' exonuclease activity
MNU43_RS05095	COG3481	metal-dependent phosphohydrolase, HD sub domain
MNU43_RS05105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MNU43_RS05120	COG0537	adenosine 5'-monophosphoramidase activity
MNU43_RS05125	COG1131	(ABC) transporter
MNU43_RS05130	COG4473	ABC transporter
MNU43_RS05140	COG2329	Antibiotic biosynthesis monooxygenase
MNU43_RS05145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MNU43_RS05150	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MNU43_RS05155	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MNU43_RS05230	COG0318	PFAM AMP-dependent synthetase and ligase
MNU43_RS05240	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MNU43_RS05245	COG0494	nUDIX hydrolase
MNU43_RS05250	COG1506	peptidase
MNU43_RS05255	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MNU43_RS05260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MNU43_RS05270	COG0656	L-ascorbic acid biosynthetic process
MNU43_RS05285	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MNU43_RS05290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MNU43_RS05300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MNU43_RS05325	COG4193	domain, Protein
MNU43_RS05325	COG3266	domain, Protein
MNU43_RS05325	COG5632	N-Acetylmuramoyl-L-alanine amidase
MNU43_RS05335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MNU43_RS05335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MNU43_RS05345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MNU43_RS05345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MNU43_RS05350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MNU43_RS05360	COG0506	proline dehydrogenase activity
MNU43_RS05365	COG2267	carboxylic ester hydrolase activity
MNU43_RS05375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MNU43_RS05380	COG1242	4 iron, 4 sulfur cluster binding
MNU43_RS05385	COG2814	Major facilitator Superfamily
MNU43_RS05390	COG0495	leucyl-tRNA aminoacylation
MNU43_RS05405	COG2081	HI0933 family
MNU43_RS05410	COG2244	polysaccharide biosynthetic process
MNU43_RS05415	COG1187	pseudouridine synthase activity
MNU43_RS05425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MNU43_RS05430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MNU43_RS05435	COG0510	thiamine kinase activity
MNU43_RS05440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MNU43_RS05450	COG1363	Peptidase, m42
MNU43_RS05455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MNU43_RS05460	COG4848	Belongs to the UPF0354 family
MNU43_RS05465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNU43_RS05470	COG1674	ftsk spoiiie
MNU43_RS05475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MNU43_RS05480	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MNU43_RS05490	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MNU43_RS05490	COG1605	Chorismate mutase
MNU43_RS05495	COG1609	Transcriptional regulator
MNU43_RS05500	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MNU43_RS05510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MNU43_RS05515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MNU43_RS05520	COG0204	Acyl-transferase
MNU43_RS05525	COG1263	PTS System
MNU43_RS05525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MNU43_RS05535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MNU43_RS05540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MNU43_RS05545	COG1764	response to oxidative stress
MNU43_RS05550	COG0584	glycerophosphoryl diester phosphodiesterase
MNU43_RS05555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MNU43_RS05560	COG1956	GAF domain-containing protein
MNU43_RS05565	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MNU43_RS05575	COG0301	tRNA thio-modification
MNU43_RS05580	COG0730	response to heat
MNU43_RS05585	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MNU43_RS05590	COG0827	DNA restriction-modification system
MNU43_RS05595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MNU43_RS05605	COG0589	response to stress
MNU43_RS05610	COG0686	Belongs to the AlaDH PNT family
MNU43_RS05615	COG0006	proline dipeptidase activity
MNU43_RS05620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MNU43_RS05630	COG4109	DRTGG domain
MNU43_RS05635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MNU43_RS05640	COG0587	DNA-directed DNA polymerase activity
MNU43_RS05645	COG0281	malic enzyme
MNU43_RS05650	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MNU43_RS05655	COG0825	malonyl-CoA metabolic process
MNU43_RS05660	COG0205	6-phosphofructokinase activity
MNU43_RS05665	COG0469	pyruvate kinase activity
MNU43_RS05670	COG1113	amino acid transport
MNU43_RS05675	COG0372	Belongs to the citrate synthase family
MNU43_RS05680	COG0538	isocitrate dehydrogenase activity
MNU43_RS05685	COG0745	RESPONSE REGULATOR receiver
MNU43_RS05690	COG5002	protein histidine kinase activity
MNU43_RS05695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MNU43_RS05695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MNU43_RS05700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MNU43_RS05705	COG0237	dephospho-CoA kinase activity
MNU43_RS05715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MNU43_RS05720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MNU43_RS05725	COG3611	Membrane attachment protein
MNU43_RS05730	COG1484	DNA-dependent DNA replication
MNU43_RS05735	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MNU43_RS05740	COG0833	amino acid
MNU43_RS05745	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MNU43_RS05750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MNU43_RS05755	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MNU43_RS05760	COG4112	unkown
MNU43_RS05770	COG0544	peptidyl-prolyl cis-trans isomerase activity
MNU43_RS05775	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MNU43_RS05780	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MNU43_RS05785	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MNU43_RS05795	COG0181	hydroxymethylbilane synthase activity
MNU43_RS05805	COG0113	porphobilinogen synthase activity
MNU43_RS05810	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MNU43_RS05820	COG2818	Glycosylase
MNU43_RS05825	COG0525	valine-tRNA ligase activity
MNU43_RS05830	COG0285	dihydrofolate synthase activity
MNU43_RS05840	COG2003	Belongs to the UPF0758 family
MNU43_RS05870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MNU43_RS05875	COG2868	ribosomal protein
MNU43_RS05880	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MNU43_RS05885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MNU43_RS05890	COG4492	Belongs to the UPF0735 family
MNU43_RS05895	COG0632	four-way junction helicase activity
MNU43_RS05900	COG2255	four-way junction helicase activity
MNU43_RS05905	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MNU43_RS05910	COG0343	queuine tRNA-ribosyltransferase activity
MNU43_RS05915	COG1862	Preprotein translocase
MNU43_RS05920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MNU43_RS05920	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MNU43_RS05930	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MNU43_RS05930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MNU43_RS05935	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MNU43_RS05940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MNU43_RS05945	COG1490	D-aminoacyl-tRNA deacylase activity
MNU43_RS05950	COG0860	N-Acetylmuramoyl-L-alanine amidase
MNU43_RS05955	COG0124	histidyl-tRNA synthetase
MNU43_RS05960	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MNU43_RS05970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MNU43_RS05975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MNU43_RS05980	COG1959	2 iron, 2 sulfur cluster binding
MNU43_RS05990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNU43_RS05995	COG1104	cysteine desulfurase activity
MNU43_RS06000	COG0482	sulfurtransferase activity
MNU43_RS06010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MNU43_RS06015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MNU43_RS06020	COG4472	Bacterial protein of unknown function (DUF965)
MNU43_RS06025	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MNU43_RS06030	COG3906	Belongs to the UPF0473 family
MNU43_RS06040	COG0826	peptidase U32
MNU43_RS06045	COG0826	peptidase U32
MNU43_RS06050	COG0572	uridine kinase
MNU43_RS06055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MNU43_RS06065	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MNU43_RS06070	COG1984	allophanate hydrolase subunit 2
MNU43_RS06075	COG0511	ligase activity, forming carbon-carbon bonds
MNU43_RS06080	COG0439	Biotin carboxylase
MNU43_RS06085	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MNU43_RS06090	COG1914	H( )-stimulated, divalent metal cation uptake system
MNU43_RS06095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MNU43_RS06100	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MNU43_RS06105	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MNU43_RS06110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MNU43_RS06115	COG1534	Rna-binding protein
MNU43_RS06120	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MNU43_RS06125	COG1713	HD superfamily hydrolase involved in NAD metabolism
MNU43_RS06130	COG0799	negative regulation of ribosome biogenesis
MNU43_RS06135	COG2226	methyltransferase
MNU43_RS06145	COG2131	deaminase
MNU43_RS06150	COG0658	competence protein
MNU43_RS06150	COG2333	competence protein COMEC
MNU43_RS06155	COG1466	dna polymerase III delta subunit
MNU43_RS06160	COG0268	Binds directly to 16S ribosomal RNA
MNU43_RS06165	COG0481	GTPase activity
MNU43_RS06170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MNU43_RS06175	COG1420	regulation of RNA biosynthetic process
MNU43_RS06180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MNU43_RS06185	COG0443	Heat shock 70 kDa protein
MNU43_RS06190	COG0484	heat shock protein binding
MNU43_RS06195	COG2264	protein methyltransferase activity
MNU43_RS06200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MNU43_RS06205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MNU43_RS06215	COG1030	water channel activity
MNU43_RS06220	COG4864	UPF0365 protein
MNU43_RS06230	COG1702	phosphate starvation-inducible protein PhoH
MNU43_RS06235	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MNU43_RS06240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MNU43_RS06250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MNU43_RS06255	COG1381	Involved in DNA repair and RecF pathway recombination
MNU43_RS06260	COG0423	glycine-tRNA ligase activity
MNU43_RS06265	COG0517	IMP dehydrogenase activity
MNU43_RS06270	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MNU43_RS06275	COG0358	DNA primase activity
MNU43_RS06280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MNU43_RS06285	COG2384	SAM-dependent methyltransferase
MNU43_RS06290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MNU43_RS06295	COG0513	Belongs to the DEAD box helicase family
MNU43_RS06300	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MNU43_RS06305	COG1121	(ABC) transporter
MNU43_RS06310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MNU43_RS06315	COG0735	belongs to the Fur family
MNU43_RS06320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MNU43_RS06325	COG0768	penicillin binding
MNU43_RS06330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MNU43_RS06335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MNU43_RS06345	COG4483	Protein conserved in bacteria
MNU43_RS06350	COG1940	carbohydrate kinase activity
MNU43_RS06355	COG0011	TIGRFAM Protein of
MNU43_RS06365	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MNU43_RS06370	COG1459	type II secretion system
MNU43_RS06375	COG4537	Required for transformation and DNA binding
MNU43_RS06395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MNU43_RS06400	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MNU43_RS06405	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MNU43_RS06410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MNU43_RS06420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MNU43_RS06425	COG0095	Lipoate-protein ligase
MNU43_RS06440	COG0006	proline dipeptidase activity
MNU43_RS06445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MNU43_RS06450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MNU43_RS06455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MNU43_RS06460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MNU43_RS06465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MNU43_RS06470	COG0511	ligase activity, forming carbon-carbon bonds
MNU43_RS06475	COG0439	Biotin carboxylase
MNU43_RS06480	COG1302	Protein conserved in bacteria
MNU43_RS06485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MNU43_RS06490	COG1570	exodeoxyribonuclease VII activity
MNU43_RS06495	COG1722	exodeoxyribonuclease VII activity
MNU43_RS06505	COG1438	arginine binding
MNU43_RS06510	COG0497	DNA recombination
MNU43_RS06515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MNU43_RS06520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MNU43_RS06525	COG0022	dehydrogenase e1 component
MNU43_RS06530	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNU43_RS06540	COG4129	membrane
MNU43_RS06550	COG2195	Cleaves the N-terminal amino acid of tripeptides
MNU43_RS06555	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MNU43_RS06560	COG0366	Alpha amylase catalytic
MNU43_RS06570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MNU43_RS06575	COG1234	tRNA 3'-trailer cleavage
MNU43_RS06580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MNU43_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
MNU43_RS06590	COG0667	Aldo Keto reductase
MNU43_RS06595	COG0494	nUDIX hydrolase
MNU43_RS06600	COG0735	belongs to the Fur family
MNU43_RS06605	COG4974	Belongs to the 'phage' integrase family
MNU43_RS06610	COG1547	Domain of unknown function (DUF309)
MNU43_RS06615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MNU43_RS06620	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MNU43_RS06625	COG1187	pseudouridine synthase activity
MNU43_RS06630	COG0745	RESPONSE REGULATOR receiver
MNU43_RS06645	COG1141	Ferredoxin
MNU43_RS06655	COG0514	ATP-dependent DNA helicase (RecQ)
MNU43_RS06660	COG1388	LysM domain
MNU43_RS06665	COG0492	ferredoxin-NADP+ reductase activity
MNU43_RS06670	COG0252	asparaginase activity
MNU43_RS06675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MNU43_RS06680	COG0539	negative regulation of cytoplasmic translation
MNU43_RS06685	COG1160	GTP binding
MNU43_RS06690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MNU43_RS06705	COG2226	methyltransferase
MNU43_RS06715	COG0105	UTP biosynthetic process
MNU43_RS06720	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MNU43_RS06725	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MNU43_RS06730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MNU43_RS06740	COG5582	Belongs to the UPF0302 family
MNU43_RS06745	COG4347	Protein of unknown function (DUF1405)
MNU43_RS06750	COG2738	Putative neutral zinc metallopeptidase
MNU43_RS06755	COG1694	Mazg nucleotide pyrophosphohydrolase
MNU43_RS06760	COG0438	transferase activity, transferring glycosyl groups
MNU43_RS06765	COG0617	tRNA 3'-terminal CCA addition
MNU43_RS06770	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MNU43_RS06770	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MNU43_RS06775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MNU43_RS06775	COG1199	ATP-dependent helicase activity
MNU43_RS06780	COG0017	Asparaginyl-tRNA synthetase
MNU43_RS06785	COG3935	DnaD domain protein
MNU43_RS06790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MNU43_RS06800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MNU43_RS06800	COG4499	WXG100 protein secretion system (Wss), protein YukC
MNU43_RS06805	COG3331	DNA recombination
MNU43_RS06815	COG4474	Belongs to the UPF0398 family
MNU43_RS06820	COG3599	regulation of cell shape
MNU43_RS06830	COG0116	Belongs to the methyltransferase superfamily
MNU43_RS06840	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MNU43_RS06845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MNU43_RS06860	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MNU43_RS06870	COG1413	lyase activity
MNU43_RS06885	COG1136	(ABC) transporter
MNU43_RS06910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MNU43_RS06915	COG2190	(PTS) system
MNU43_RS06920	COG4479	Belongs to the UPF0346 family
MNU43_RS06925	COG0793	Belongs to the peptidase S41A family
MNU43_RS06935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MNU43_RS06940	COG0671	phosphoesterase, PA-phosphatase related
MNU43_RS06945	COG3842	ATPase activity
MNU43_RS06950	COG4209	transmembrane transport
MNU43_RS06960	COG0395	ABC-type sugar transport system, permease component
MNU43_RS06970	COG0534	Mate efflux family protein
MNU43_RS06975	COG1349	DNA-binding transcription factor activity
MNU43_RS06980	COG0745	RESPONSE REGULATOR receiver
MNU43_RS06985	COG5002	protein histidine kinase activity
MNU43_RS06990	COG0567	Dehydrogenase, E1 component
MNU43_RS06995	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNU43_RS07015	COG0714	Associated with various cellular activities
MNU43_RS07020	COG4548	von Willebrand factor, type A
MNU43_RS07025	COG1114	Component of the transport system for branched-chain amino acids
MNU43_RS07030	COG3853	Toxic anion resistance protein (TelA)
MNU43_RS07040	COG1254	Belongs to the acylphosphatase family
MNU43_RS07050	COG1278	Cold shock
MNU43_RS07065	COG1131	(ABC) transporter
MNU43_RS07085	COG1473	amidohydrolase
MNU43_RS07090	COG2171	N-acyltransferase activity
MNU43_RS07095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MNU43_RS07100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MNU43_RS07105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MNU43_RS07110	COG0527	aspartate kinase activity
MNU43_RS07115	COG0488	(ABC) transporter
MNU43_RS07120	COG2996	Protein conserved in bacteria
MNU43_RS07125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MNU43_RS07130	COG0573	inorganic phosphate transmembrane transporter activity
MNU43_RS07135	COG0581	inorganic phosphate transmembrane transporter activity
MNU43_RS07140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MNU43_RS07145	COG0704	Plays a role in the regulation of phosphate uptake
MNU43_RS07185	COG2348	transferase activity, transferring amino-acyl groups
MNU43_RS07190	COG2348	transferase activity, transferring amino-acyl groups
MNU43_RS07200	COG0159	tryptophan synthase activity
MNU43_RS07205	COG0133	tryptophan synthase activity
MNU43_RS07210	COG0135	phosphoribosylanthranilate isomerase activity
MNU43_RS07215	COG0134	indole-3-glycerol-phosphate synthase activity
MNU43_RS07220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MNU43_RS07225	COG0512	Glutamine amidotransferase of anthranilate synthase
MNU43_RS07225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MNU43_RS07230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MNU43_RS07235	COG0287	Prephenate dehydrogenase
MNU43_RS07240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MNU43_RS07245	COG1942	4-Oxalocrotonate Tautomerase
MNU43_RS07260	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MNU43_RS07260	COG0392	lysyltransferase activity
MNU43_RS07265	COG0628	permease
MNU43_RS07270	COG3711	transcriptional antiterminator
MNU43_RS07275	COG1115	amino acid carrier protein
MNU43_RS07280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MNU43_RS07285	COG0187	DNA topoisomerase II activity
MNU43_RS07290	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MNU43_RS07295	COG4841	protein insertion into membrane
MNU43_RS07300	COG0824	Thioesterase
MNU43_RS07305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MNU43_RS07310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MNU43_RS07315	COG1970	mechanosensitive ion channel activity
MNU43_RS07320	COG0419	ATPase involved in DNA repair
MNU43_RS07325	COG0420	3'-5' exonuclease activity
MNU43_RS07330	COG4846	Membrane protein involved in cytochrome C biogenesis
MNU43_RS07340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MNU43_RS07345	COG4224	UPF0291 protein
MNU43_RS07355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MNU43_RS07360	COG2340	Cysteine-rich secretory protein family
MNU43_RS07365	COG0516	GMP reductase activity
MNU43_RS07370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MNU43_RS07380	COG0753	catalase activity
MNU43_RS07385	COG0833	amino acid
MNU43_RS07400	COG0083	homoserine kinase activity
MNU43_RS07405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MNU43_RS07410	COG0460	homoserine dehydrogenase
MNU43_RS07415	COG0527	aspartate kinase activity
MNU43_RS07430	COG1525	nuclease
MNU43_RS07440	COG2197	response regulator
MNU43_RS07445	COG4585	Histidine kinase
MNU43_RS07455	COG1131	(ABC) transporter
MNU43_RS07460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNU43_RS07510	COG0174	glutamine synthetase
MNU43_RS07515	COG0789	Transcriptional regulator
MNU43_RS07520	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MNU43_RS07525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MNU43_RS07530	COG0386	Belongs to the glutathione peroxidase family
MNU43_RS07535	COG1923	regulation of RNA biosynthetic process
MNU43_RS07540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MNU43_RS07550	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MNU43_RS07555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MNU43_RS07560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MNU43_RS07565	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MNU43_RS07570	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MNU43_RS07575	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MNU43_RS07585	COG4550	Control of competence regulator ComK, YlbF/YmcA
MNU43_RS07590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MNU43_RS07600	COG4195	phage-related replication protein
MNU43_RS07605	COG1013	pyruvate-flavodoxin oxidoreductase activity
MNU43_RS07610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MNU43_RS07610	COG0674	pyruvate-flavodoxin oxidoreductase activity
MNU43_RS07615	COG1692	metallophosphoesterase
MNU43_RS07625	COG1418	mRNA catabolic process
MNU43_RS07630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MNU43_RS07640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MNU43_RS07655	COG0300	oxidoreductase activity
MNU43_RS07660	COG0612	Peptidase, M16
MNU43_RS07665	COG0612	Peptidase, M16
MNU43_RS07670	COG2188	Transcriptional regulator
MNU43_RS07675	COG1674	ftsk spoiiie
MNU43_RS07680	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MNU43_RS07685	COG1185	polyribonucleotide nucleotidyltransferase activity
MNU43_RS07690	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MNU43_RS07695	COG0196	riboflavin kinase activity
MNU43_RS07700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MNU43_RS07705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MNU43_RS07710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MNU43_RS07715	COG1358	cellular component organization or biogenesis
MNU43_RS07720	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MNU43_RS07725	COG0195	Participates in both transcription termination and antitermination
MNU43_RS07730	COG0779	Required for maturation of 30S ribosomal subunits
MNU43_RS07735	COG2176	DNA-directed DNA polymerase activity
MNU43_RS07740	COG0442	prolyl-tRNA aminoacylation
MNU43_RS07750	COG4589	Belongs to the CDS family
MNU43_RS07755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MNU43_RS07760	COG0233	cytoplasmic translational termination
MNU43_RS07765	COG0528	UMP kinase activity
MNU43_RS07770	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MNU43_RS07775	COG0052	Belongs to the universal ribosomal protein uS2 family
MNU43_RS07780	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MNU43_RS07785	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MNU43_RS07790	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MNU43_RS07795	COG4974	Belongs to the 'phage' integrase family
MNU43_RS07800	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MNU43_RS07805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MNU43_RS07810	COG0758	DNA mediated transformation
MNU43_RS07820	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MNU43_RS07825	COG0045	succinate-CoA ligase (ADP-forming) activity
MNU43_RS07830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MNU43_RS07840	COG4485	Bacterial membrane protein, YfhO
MNU43_RS07850	COG0335	large ribosomal subunit rRNA binding
MNU43_RS07855	COG0336	Belongs to the RNA methyltransferase TrmD family
MNU43_RS07860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MNU43_RS07865	COG0228	four-way junction DNA binding
MNU43_RS07870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MNU43_RS07875	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MNU43_RS07880	COG0552	protein localization to endoplasmic reticulum
MNU43_RS07885	COG1196	nuclear chromosome segregation
MNU43_RS07890	COG0571	ribonuclease III activity
MNU43_RS07895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MNU43_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
MNU43_RS07910	COG0416	fatty acid biosynthetic process
MNU43_RS07915	COG1349	DNA-binding transcription factor activity
MNU43_RS07920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MNU43_RS07925	COG1461	Dihydroxyacetone kinase
MNU43_RS07930	COG1302	Protein conserved in bacteria
MNU43_RS07935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MNU43_RS07945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MNU43_RS07950	COG1162	GTPase activity
MNU43_RS07960	COG0631	protein serine/threonine phosphatase activity
MNU43_RS07965	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MNU43_RS07970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MNU43_RS07970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MNU43_RS07975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MNU43_RS07980	COG0242	peptide deformylase activity
MNU43_RS07990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MNU43_RS07995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MNU43_RS08000	COG1758	RNA polymerase activity
MNU43_RS08005	COG0194	GDP metabolic process
MNU43_RS08025	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MNU43_RS08030	COG0284	orotidine-5'-phosphate decarboxylase activity
MNU43_RS08035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MNU43_RS08040	COG0505	Belongs to the CarA family
MNU43_RS08045	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MNU43_RS08050	COG0540	Belongs to the ATCase OTCase family
MNU43_RS08055	COG2233	PERMEase
MNU43_RS08060	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MNU43_RS08065	COG0564	pseudouridine synthase activity
MNU43_RS08070	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MNU43_RS08075	COG1388	LysM domain
MNU43_RS08075	COG3942	CHAP domain
MNU43_RS08085	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MNU43_RS08090	COG3599	regulation of cell shape
MNU43_RS08100	COG0762	integral membrane protein
MNU43_RS08105	COG1799	cell septum assembly
MNU43_RS08110	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MNU43_RS08115	COG1496	oxidoreductase activity
MNU43_RS08120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MNU43_RS08125	COG0849	cell division
MNU43_RS08130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MNU43_RS08135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MNU43_RS08140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MNU43_RS08145	COG0768	penicillin binding
MNU43_RS08150	COG4839	cell division protein FtsL
MNU43_RS08155	COG0275	rRNA processing
MNU43_RS08160	COG2001	Belongs to the MraZ family
MNU43_RS08165	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MNU43_RS08170	COG0454	-acetyltransferase
MNU43_RS08175	COG1011	Hydrolase
MNU43_RS08220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MNU43_RS08225	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MNU43_RS08230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MNU43_RS08235	COG1053	succinate dehydrogenase
MNU43_RS08240	COG2009	succinate dehydrogenase
MNU43_RS08250	COG0322	excinuclease ABC activity
MNU43_RS08255	COG3118	belongs to the thioredoxin family
MNU43_RS08260	COG1193	negative regulation of DNA recombination
MNU43_RS08265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MNU43_RS08265	COG1796	DNA polymerase
MNU43_RS08275	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MNU43_RS08280	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MNU43_RS08285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNU43_RS08285	COG0072	phenylalanine-tRNA ligase activity
MNU43_RS08290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MNU43_RS08295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNU43_RS08305	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MNU43_RS08315	COG1323	Belongs to the UPF0348 family
MNU43_RS08320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MNU43_RS08325	COG0742	ribosomal rna small subunit methyltransferase
MNU43_RS08335	COG4471	UPF0298 protein
MNU43_RS08340	COG0584	glycerophosphoryl diester phosphodiesterase
MNU43_RS08345	COG3679	Belongs to the UPF0342 family
MNU43_RS08350	COG2340	Cysteine-rich secretory protein family
MNU43_RS08360	COG0109	protoheme IX farnesyltransferase activity
MNU43_RS08365	COG1612	heme a metabolic process
MNU43_RS08375	COG0772	Belongs to the SEDS family
MNU43_RS08380	COG4838	Belongs to the UPF0358 family
MNU43_RS08385	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MNU43_RS08390	COG4896	Protein conserved in bacteria
MNU43_RS08405	COG1217	gtp-binding protein TYPA
MNU43_RS08415	COG0483	inositol monophosphate 1-phosphatase activity
MNU43_RS08420	COG4493	Belongs to the UPF0637 family
MNU43_RS08425	COG1914	H( )-stimulated, divalent metal cation uptake system
MNU43_RS08450	COG1176	ABC-type spermidine putrescine transport system, permease component I
MNU43_RS08455	COG3842	ATPase activity
MNU43_RS08465	COG4476	Belongs to the UPF0223 family
MNU43_RS08475	COG0508	dehydrogenase complex catalyzes the overall conversion of
MNU43_RS08480	COG0022	dehydrogenase e1 component
MNU43_RS08485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MNU43_RS08495	COG0242	peptide deformylase activity
MNU43_RS08500	COG5503	Protein of unknown function (DUF1447)
MNU43_RS08505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MNU43_RS08510	COG0569	domain protein
MNU43_RS08515	COG1294	oxidase, subunit
MNU43_RS08520	COG1271	oxidase subunit
MNU43_RS08530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MNU43_RS08535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MNU43_RS08545	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MNU43_RS08560	COG4716	Myosin-crossreactive antigen
MNU43_RS08570	COG4172	Belongs to the ABC transporter superfamily
MNU43_RS08575	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNU43_RS08580	COG0151	Belongs to the GarS family
MNU43_RS08585	COG0138	bifunctional purine biosynthesis protein purh
MNU43_RS08590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MNU43_RS08595	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MNU43_RS08600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MNU43_RS08605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNU43_RS08610	COG0047	phosphoribosylformylglycinamidine synthase activity
MNU43_RS08615	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNU43_RS08620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MNU43_RS08625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MNU43_RS08630	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MNU43_RS08635	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MNU43_RS08645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MNU43_RS08650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MNU43_RS08655	COG1845	cytochrome c oxidase, subunit III
MNU43_RS08660	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MNU43_RS08675	COG1316	TRANSCRIPTIONal
MNU43_RS08700	COG3594	Acyltransferase
MNU43_RS08705	COG0436	Aminotransferase
MNU43_RS08710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MNU43_RS08720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MNU43_RS08725	COG1169	isochorismate synthase
MNU43_RS08730	COG1575	Belongs to the MenA family. Type 1 subfamily
MNU43_RS08735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MNU43_RS08740	COG2314	TM2 domain
MNU43_RS08795	COG4873	Protein conserved in bacteria
MNU43_RS08805	COG0737	Belongs to the 5'-nucleotidase family
MNU43_RS08810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MNU43_RS08815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MNU43_RS08820	COG0861	Integral membrane protein TerC family
MNU43_RS08825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MNU43_RS08835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MNU43_RS08840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MNU43_RS08845	COG2814	Major facilitator Superfamily
MNU43_RS08850	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MNU43_RS08855	COG2382	esterase
MNU43_RS08860	COG0628	permease
MNU43_RS08900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MNU43_RS08905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MNU43_RS08910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MNU43_RS08935	COG0569	domain protein
MNU43_RS08935	COG0475	glutathione-regulated potassium exporter activity
MNU43_RS08940	COG2239	Acts as a magnesium transporter
MNU43_RS08945	COG0564	pseudouridine synthase activity
MNU43_RS08950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MNU43_RS08955	COG2357	RelA SpoT domain protein
MNU43_RS08970	COG2346	COG2346, Truncated hemoglobins
MNU43_RS08975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MNU43_RS08980	COG1164	Oligoendopeptidase f
MNU43_RS08990	COG4862	establishment of competence for transformation
MNU43_RS09000	COG1393	Belongs to the ArsC family
MNU43_RS09005	COG0180	Tryptophanyl-tRNA synthetase
MNU43_RS09010	COG4166	transmembrane transport
MNU43_RS09015	COG4608	Belongs to the ABC transporter superfamily
MNU43_RS09020	COG0444	Belongs to the ABC transporter superfamily
MNU43_RS09025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MNU43_RS09030	COG0601	transmembrane transport
MNU43_RS09045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MNU43_RS09055	COG0542	response to heat
MNU43_RS09070	COG0561	phosphatase activity
MNU43_RS09075	COG0446	pyridine nucleotide-disulphide oxidoreductase
MNU43_RS09085	COG0179	Fumarylacetoacetate (FAA) hydrolase
MNU43_RS09090	COG1074	ATP-dependent DNA helicase activity
MNU43_RS09095	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MNU43_RS09110	COG0398	Pfam SNARE associated Golgi protein
MNU43_RS09115	COG0166	Belongs to the GPI family
MNU43_RS09120	COG0137	argininosuccinate synthase activity
MNU43_RS09125	COG0165	Argininosuccinate lyase
MNU43_RS09130	COG0584	glycerophosphoryl diester phosphodiesterase
MNU43_RS09140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MNU43_RS09155	COG1902	pentaerythritol trinitrate reductase activity
MNU43_RS09160	COG1098	S1 RNA binding domain
MNU43_RS09165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MNU43_RS09175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MNU43_RS09175	COG2111	Na H antiporter
MNU43_RS09180	COG2111	Na H antiporter
MNU43_RS09185	COG1006	Multisubunit Na H antiporter MnhC subunit
MNU43_RS09190	COG0651	ATP synthesis coupled electron transport
MNU43_RS09195	COG1863	multisubunit Na H antiporter MnhE subunit
MNU43_RS09200	COG2212	antiporter activity
MNU43_RS09205	COG1320	monovalent cation:proton antiporter activity
MNU43_RS09215	COG2050	protein possibly involved in aromatic compounds catabolism
MNU43_RS09220	COG2056	Na+-H+ antiporter family
MNU43_RS09225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MNU43_RS09230	COG1252	NADH dehydrogenase
MNU43_RS09235	COG0316	Belongs to the HesB IscA family
MNU43_RS09240	COG4844	belongs to the
MNU43_RS09245	COG1252	NADH dehydrogenase
MNU43_RS09250	COG4837	Protein of unknown function (DUF1462)
MNU43_RS09255	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MNU43_RS09260	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MNU43_RS09265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MNU43_RS09270	COG1696	Membrane protein involved in D-alanine export
MNU43_RS09275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MNU43_RS09285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNU43_RS09290	COG0647	UMP catabolic process
MNU43_RS09295	COG2445	Protein of unknown function DUF86
MNU43_RS09305	COG4470	Protein conserved in bacteria
MNU43_RS09310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MNU43_RS09315	COG0737	Belongs to the 5'-nucleotidase family
MNU43_RS09320	COG0730	response to heat
MNU43_RS09325	COG1801	Protein of unknown function DUF72
MNU43_RS09330	COG1253	flavin adenine dinucleotide binding
MNU43_RS09345	COG0719	Fe-S assembly protein
MNU43_RS09350	COG0822	iron-sulfur transferase activity
MNU43_RS09355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MNU43_RS09360	COG0719	Fe-S assembly protein
MNU43_RS09365	COG0396	ATPase activity
MNU43_RS09375	COG3237	CsbD-like
MNU43_RS09385	COG1464	Belongs to the NlpA lipoprotein family
MNU43_RS09390	COG2011	ABC-type metal ion transport system permease component
MNU43_RS09395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MNU43_RS09405	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MNU43_RS09410	COG0509	glycine decarboxylation via glycine cleavage system
MNU43_RS09415	COG1393	Belongs to the ArsC family
MNU43_RS09420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MNU43_RS09430	COG0710	3-dehydroquinate dehydratase activity
MNU43_RS09435	COG1764	response to oxidative stress
MNU43_RS09495	COG4195	phage-related replication protein
MNU43_RS09510	COG1278	Cold shock
MNU43_RS09540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MNU43_RS09585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MNU43_RS09590	COG0557	exoribonuclease II activity
MNU43_RS09595	COG1647	Serine aminopeptidase, S33
MNU43_RS09600	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MNU43_RS09610	COG0148	phosphopyruvate hydratase activity
MNU43_RS09615	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MNU43_RS09620	COG0149	triose-phosphate isomerase activity
MNU43_RS09625	COG0126	phosphoglycerate kinase activity
MNU43_RS09630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MNU43_RS09650	COG1090	epimerase
MNU43_RS09660	COG0740	serine-type endopeptidase activity
MNU43_RS09670	COG1481	regulation of sporulation
MNU43_RS09675	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MNU43_RS09680	COG1660	Displays ATPase and GTPase activities
MNU43_RS09685	COG0492	ferredoxin-NADP+ reductase activity
MNU43_RS09700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MNU43_RS09705	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MNU43_RS09710	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MNU43_RS09715	COG0556	nucleotide-excision repair
MNU43_RS09730	COG3942	CHAP domain
MNU43_RS09730	COG1388	LysM domain
MNU43_RS09740	COG0653	protein targeting
MNU43_RS09745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MNU43_RS09750	COG1040	competence protein
MNU43_RS09755	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MNU43_RS09765	COG1739	Uncharacterized protein family UPF0029
MNU43_RS09770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MNU43_RS09775	COG2199	diguanylate cyclase activity
MNU43_RS09790	COG2195	Cleaves the N-terminal amino acid of tripeptides
MNU43_RS09795	COG1929	Belongs to the glycerate kinase type-1 family
MNU43_RS09815	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MNU43_RS09830	COG4604	ABC transporter, ATP-binding protein
MNU43_RS09835	COG4605	iron ion homeostasis
MNU43_RS09840	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MNU43_RS09850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNU43_RS09855	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNU43_RS09860	COG1780	Probably involved in ribonucleotide reductase function
MNU43_RS09870	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MNU43_RS09875	COG3104	oligopeptide transport
MNU43_RS09885	COG1597	lipid kinase activity
MNU43_RS09890	COG1454	alcohol dehydrogenase
MNU43_RS09890	COG1012	belongs to the aldehyde dehydrogenase family
MNU43_RS09895	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MNU43_RS09900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MNU43_RS09905	COG1174	glycine betaine transport
MNU43_RS09915	COG0514	ATP-dependent DNA helicase (RecQ)
MNU43_RS09920	COG0488	(ABC) transporter
MNU43_RS09940	COG1368	sulfuric ester hydrolase activity
MNU43_RS09950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MNU43_RS09965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MNU43_RS09975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MNU43_RS09980	COG0720	synthase
MNU43_RS09985	COG0602	queuosine metabolic process
MNU43_RS10010	COG0745	RESPONSE REGULATOR receiver
MNU43_RS10015	COG5002	protein histidine kinase activity
MNU43_RS10020	COG0463	Glycosyl transferase, family 2
MNU43_RS10025	COG0656	L-ascorbic acid biosynthetic process
MNU43_RS10030	COG1253	flavin adenine dinucleotide binding
MNU43_RS10035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MNU43_RS10040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MNU43_RS10040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MNU43_RS10040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MNU43_RS10045	COG1105	Belongs to the carbohydrate kinase PfkB family
MNU43_RS10050	COG1349	DNA-binding transcription factor activity
MNU43_RS10055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MNU43_RS10080	COG0415	Belongs to the DNA photolyase family
MNU43_RS10085	COG0471	metal ion transport
MNU43_RS10090	COG0039	L-malate dehydrogenase activity
MNU43_RS10110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MNU43_RS10115	COG4988	ABC transporter
MNU43_RS10120	COG1968	undecaprenyl-diphosphatase activity
MNU43_RS10135	COG1671	Belongs to the UPF0178 family
MNU43_RS10140	COG1611	Belongs to the LOG family
MNU43_RS10165	COG2839	Protein conserved in bacteria
MNU43_RS10170	COG2814	Major facilitator Superfamily
MNU43_RS10175	COG0583	DNA-binding transcription factor activity
MNU43_RS10195	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MNU43_RS10205	COG0217	transcriptional regulatory protein
MNU43_RS10225	COG1388	LysM domain
MNU43_RS10225	COG3942	CHAP domain
MNU43_RS10230	COG0306	phosphate transporter
MNU43_RS10235	COG1392	Phosphate transport regulator
MNU43_RS10240	COG0577	efflux transmembrane transporter activity
MNU43_RS10245	COG1136	(ABC) transporter
MNU43_RS10250	COG2205	protein histidine kinase activity
MNU43_RS10255	COG0745	RESPONSE REGULATOR receiver
MNU43_RS10260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MNU43_RS10275	COG3949	Membrane
MNU43_RS10285	COG1120	ATPase activity
MNU43_RS10290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MNU43_RS10295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MNU43_RS10300	COG1132	(ABC) transporter
MNU43_RS10305	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MNU43_RS10315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MNU43_RS10320	COG1682	transport, permease protein
MNU43_RS10325	COG1134	teichoic acid transport
MNU43_RS10330	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MNU43_RS10340	COG1321	iron dependent repressor
MNU43_RS10345	COG1121	(ABC) transporter
MNU43_RS10350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MNU43_RS10355	COG0803	Belongs to the bacterial solute-binding protein 9 family
MNU43_RS10365	COG1320	monovalent cation:proton antiporter activity
MNU43_RS10370	COG2212	antiporter activity
MNU43_RS10375	COG1863	multisubunit Na H antiporter MnhE subunit
MNU43_RS10380	COG0651	ATP synthesis coupled electron transport
MNU43_RS10385	COG1006	Multisubunit Na H antiporter MnhC subunit
MNU43_RS10390	COG2111	Na H antiporter
MNU43_RS10395	COG2111	Na H antiporter
MNU43_RS10395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MNU43_RS10430	COG0596	Alpha beta hydrolase
MNU43_RS10450	COG0546	phosphoglycolate phosphatase activity
MNU43_RS10455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MNU43_RS10460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MNU43_RS10470	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MNU43_RS10475	COG0018	arginyl-trna synthetase
MNU43_RS10495	COG1064	alcohol dehydrogenase
MNU43_RS10500	COG3875	lactate racemase activity
MNU43_RS10505	COG1606	tRNA processing
MNU43_RS10510	COG1691	(AIR) carboxylase
MNU43_RS10515	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MNU43_RS10525	COG1078	dGTPase activity
MNU43_RS10545	COG2113	Glycine betaine
MNU43_RS10550	COG2409	Drug exporters of the RND superfamily
MNU43_RS10555	COG0667	Aldo Keto reductase
MNU43_RS10570	COG1388	LysM domain
MNU43_RS10570	COG0860	N-Acetylmuramoyl-L-alanine amidase
MNU43_RS10630	COG5434	Belongs to the glycosyl hydrolase 28 family
MNU43_RS10715	COG1783	phage Terminase large subunit
MNU43_RS10825	COG0305	Participates in initiation and elongation during chromosome replication
MNU43_RS10870	COG3646	Phage regulatory protein
MNU43_RS10870	COG3645	SOS response
MNU43_RS10905	COG4844	belongs to the
MNU43_RS10925	COG0095	Lipoate-protein ligase
MNU43_RS10930	COG0280	phosphate acetyltransferase
MNU43_RS10935	COG3253	May function as heme-dependent peroxidase
MNU43_RS10955	COG0531	amino acid
MNU43_RS10960	COG2363	Small membrane protein
MNU43_RS10970	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MNU43_RS10980	COG0351	phosphomethylpyrimidine kinase
MNU43_RS11000	COG0183	Belongs to the thiolase family
MNU43_RS11005	COG0318	PFAM AMP-dependent synthetase and ligase
MNU43_RS11015	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MNU43_RS11020	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MNU43_RS11025	COG0363	glucosamine-6-phosphate deaminase activity
MNU43_RS11040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MNU43_RS11045	COG1469	GTP cyclohydrolase I activity
MNU43_RS11075	COG0431	NADPH-dependent FMN reductase
MNU43_RS11080	COG0561	phosphatase activity
MNU43_RS11090	COG1428	Deoxynucleoside kinase
MNU43_RS11095	COG1428	Deoxynucleoside kinase
MNU43_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
MNU43_RS11105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MNU43_RS11110	COG0546	phosphoglycolate phosphatase activity
MNU43_RS11120	COG1063	alcohol dehydrogenase
MNU43_RS11125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MNU43_RS11130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MNU43_RS11135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MNU43_RS11155	COG1473	amidohydrolase
MNU43_RS11160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MNU43_RS11165	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MNU43_RS11175	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MNU43_RS11185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNU43_RS11190	COG0085	RNA polymerase activity
MNU43_RS11195	COG2813	Specifically methylates the guanine in position
MNU43_RS11200	COG0222	ribosome binding
MNU43_RS11205	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MNU43_RS11210	COG0081	regulation of translation
MNU43_RS11215	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MNU43_RS11220	COG0250	Participates in transcription elongation, termination and antitermination
MNU43_RS11225	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MNU43_RS11230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MNU43_RS11240	COG3688	RNA-binding protein containing a PIN domain
MNU43_RS11245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNU43_RS11250	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MNU43_RS11255	COG0215	cysteine-tRNA ligase activity
MNU43_RS11260	COG1045	serine acetyltransferase
MNU43_RS11265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MNU43_RS11270	COG4956	integral membrane protein (PIN domain superfamily)
MNU43_RS11275	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MNU43_RS11280	COG0542	response to heat
MNU43_RS11285	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MNU43_RS11290	COG3880	PFAM UvrB UvrC protein
MNU43_RS11295	COG4463	regulation of RNA biosynthetic process
MNU43_RS11300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MNU43_RS11310	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MNU43_RS11315	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MNU43_RS11320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MNU43_RS11410	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MNU43_RS11415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MNU43_RS11420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MNU43_RS11425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MNU43_RS11430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MNU43_RS11435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MNU43_RS11440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MNU43_RS11445	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MNU43_RS11450	COG0037	tRNA processing
MNU43_RS11455	COG1098	S1 RNA binding domain
MNU43_RS11465	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MNU43_RS11470	COG3956	TIGRFAM MazG family protein
MNU43_RS11475	COG2244	polysaccharide biosynthetic process
MNU43_RS11480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MNU43_RS11485	COG0193	aminoacyl-tRNA hydrolase activity
MNU43_RS11490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MNU43_RS11495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MNU43_RS11500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MNU43_RS11505	COG2088	sporulation resulting in formation of a cellular spore
MNU43_RS11510	COG0251	oxidation-reduction process
MNU43_RS11515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MNU43_RS11520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MNU43_RS11525	COG4466	Protein conserved in bacteria
MNU43_RS11530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MNU43_RS11535	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MNU43_RS11540	COG0084	hydrolase, TatD family'
MNU43_RS11545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNU43_RS11545	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNU43_RS11550	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MNU43_RS11555	COG2827	Endonuclease containing a URI domain
MNU43_RS11560	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MNU43_RS11565	COG4467	Involved in initiation control of chromosome replication
MNU43_RS11570	COG1774	PSP1 C-terminal conserved region
MNU43_RS11575	COG0470	DNA polymerase III
MNU43_RS11580	COG3870	Protein conserved in bacteria
MNU43_RS11585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MNU43_RS11590	COG1982	Orn Lys Arg decarboxylase major
MNU43_RS11615	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MNU43_RS11620	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MNU43_RS11625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MNU43_RS11645	COG2855	membrane
MNU43_RS11650	COG0583	DNA-binding transcription factor activity
MNU43_RS11660	COG0493	'glutamate synthase
MNU43_RS11665	COG0067	glutamate synthase
MNU43_RS11665	COG0069	glutamate synthase activity
MNU43_RS11665	COG0070	glutamate synthase
MNU43_RS11670	COG0583	DNA-binding transcription factor activity
MNU43_RS11695	COG0438	transferase activity, transferring glycosyl groups
MNU43_RS11700	COG1388	LysM domain
MNU43_RS11700	COG3942	CHAP domain
MNU43_RS11710	COG2011	ABC-type metal ion transport system permease component
MNU43_RS11715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MNU43_RS11720	COG0626	cystathionine gamma-synthase activity
MNU43_RS11725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MNU43_RS11735	COG0733	neurotransmitter:sodium symporter activity
MNU43_RS11745	COG1647	Serine aminopeptidase, S33
MNU43_RS11760	COG5609	conserved protein (DUF2294)
MNU43_RS11765	COG3002	Belongs to the UPF0753 family
MNU43_RS11770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MNU43_RS11785	COG0523	cobalamin synthesis protein
MNU43_RS11830	COG0519	Catalyzes the synthesis of GMP from XMP
MNU43_RS11830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MNU43_RS11835	COG0517	IMP dehydrogenase activity
MNU43_RS11835	COG0516	GMP reductase activity
MNU43_RS11840	COG2233	PERMEase
MNU43_RS11845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MNU43_RS11860	COG5183	chlorophyll binding
MNU43_RS11865	COG1823	symporter activity
MNU43_RS11870	COG0778	Nitroreductase
MNU43_RS11880	COG0450	alkyl hydroperoxide reductase
MNU43_RS11885	COG3634	alkyl hydroperoxide reductase activity
MNU43_RS11905	COG1280	lysine exporter protein (LysE YggA)
MNU43_RS11925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MNU43_RS11935	COG0360	Binds together with S18 to 16S ribosomal RNA
MNU43_RS11950	COG0012	GTP binding
MNU43_RS11955	COG4481	Protein conserved in bacteria
MNU43_RS11960	COG0668	transmembrane transport
MNU43_RS11965	COG1475	DNA binding
MNU43_RS11970	COG0626	cystathionine gamma-synthase activity
MNU43_RS11975	COG0626	cystathionine gamma-synthase activity
MNU43_RS11980	COG0646	methionine synthase
MNU43_RS11980	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MNU43_RS11985	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MNU43_RS11995	COG0183	Belongs to the thiolase family
MNU43_RS12010	COG1476	TRANSCRIPTIONal
MNU43_RS12020	COG4555	ABC transporter
MNU43_RS12040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MNU43_RS12080	COG1136	(ABC) transporter
MNU43_RS12085	COG0577	efflux transmembrane transporter activity
MNU43_RS12105	COG0577	efflux transmembrane transporter activity
MNU43_RS12110	COG1136	(ABC) transporter
MNU43_RS12145	COG1475	DNA binding
MNU43_RS12150	COG0357	Ribosomal RNA small subunit methyltransferase G
MNU43_RS12155	COG0445	tRNA wobble uridine modification
MNU43_RS12160	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MNU43_RS12165	COG0594	ribonuclease P activity
MNU43_RS12185	COG1388	LysM domain
MNU43_RS12185	COG3942	CHAP domain
MNU43_RS12265	COG1192	Involved in chromosome partitioning
MNU43_RS12290	COG1686	Belongs to the peptidase S11 family
MNU43_RS12325	COG3237	CsbD-like
MNU43_RS12385	COG3764	Sortase (surface protein transpeptidase)