locus-tag	class	description
IAU62_RS00005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAU62_RS00010	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IAU62_RS00015	COG1063	alcohol dehydrogenase
IAU62_RS00020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAU62_RS00030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAU62_RS00035	COG1028	Short-chain dehydrogenase reductase Sdr
IAU62_RS00040	COG1428	Deoxynucleoside kinase
IAU62_RS00045	COG1428	Deoxynucleoside kinase
IAU62_RS00055	COG0561	phosphatase activity
IAU62_RS00060	COG0431	NADPH-dependent FMN reductase
IAU62_RS00075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAU62_RS00080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAU62_RS00090	COG1469	GTP cyclohydrolase I activity
IAU62_RS00095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IAU62_RS00105	COG0363	glucosamine-6-phosphate deaminase activity
IAU62_RS00110	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IAU62_RS00125	COG0318	PFAM AMP-dependent synthetase and ligase
IAU62_RS00130	COG0183	Belongs to the thiolase family
IAU62_RS00145	COG0477	Major facilitator Superfamily
IAU62_RS00160	COG0351	phosphomethylpyrimidine kinase
IAU62_RS00170	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IAU62_RS00180	COG2363	Small membrane protein
IAU62_RS00185	COG0531	amino acid
IAU62_RS00200	COG3253	May function as heme-dependent peroxidase
IAU62_RS00205	COG0280	phosphate acetyltransferase
IAU62_RS00210	COG0095	Lipoate-protein ligase
IAU62_RS00230	COG4844	belongs to the
IAU62_RS00255	COG2409	Drug exporters of the RND superfamily
IAU62_RS00260	COG2113	Glycine betaine
IAU62_RS00280	COG1078	dGTPase activity
IAU62_RS00290	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IAU62_RS00295	COG1691	(AIR) carboxylase
IAU62_RS00300	COG1606	tRNA processing
IAU62_RS00305	COG3875	lactate racemase activity
IAU62_RS00310	COG1064	alcohol dehydrogenase
IAU62_RS00325	COG0018	arginyl-trna synthetase
IAU62_RS00330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAU62_RS00340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAU62_RS00345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAU62_RS00350	COG0546	phosphoglycolate phosphatase activity
IAU62_RS00370	COG0596	Alpha beta hydrolase
IAU62_RS00400	COG2111	Na H antiporter
IAU62_RS00400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAU62_RS00405	COG2111	Na H antiporter
IAU62_RS00410	COG1006	Multisubunit Na H antiporter MnhC subunit
IAU62_RS00415	COG0651	ATP synthesis coupled electron transport
IAU62_RS00420	COG1863	multisubunit Na H antiporter MnhE subunit
IAU62_RS00425	COG2212	antiporter activity
IAU62_RS00430	COG1320	monovalent cation:proton antiporter activity
IAU62_RS00440	COG0803	Belongs to the bacterial solute-binding protein 9 family
IAU62_RS00445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAU62_RS00450	COG1121	(ABC) transporter
IAU62_RS00455	COG1321	iron dependent repressor
IAU62_RS00465	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IAU62_RS00470	COG1134	teichoic acid transport
IAU62_RS00475	COG1682	transport, permease protein
IAU62_RS00480	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAU62_RS00490	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IAU62_RS00495	COG1132	(ABC) transporter
IAU62_RS00500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAU62_RS00510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAU62_RS00515	COG1120	ATPase activity
IAU62_RS00525	COG3949	Membrane
IAU62_RS00540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAU62_RS00545	COG0745	RESPONSE REGULATOR receiver
IAU62_RS00550	COG2205	protein histidine kinase activity
IAU62_RS00555	COG1136	(ABC) transporter
IAU62_RS00560	COG0577	efflux transmembrane transporter activity
IAU62_RS00565	COG1392	Phosphate transport regulator
IAU62_RS00570	COG0306	phosphate transporter
IAU62_RS00575	COG1388	LysM domain
IAU62_RS00575	COG3942	CHAP domain
IAU62_RS00595	COG0217	transcriptional regulatory protein
IAU62_RS00605	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
IAU62_RS00625	COG0583	DNA-binding transcription factor activity
IAU62_RS00630	COG2814	Major facilitator Superfamily
IAU62_RS00635	COG2839	Protein conserved in bacteria
IAU62_RS00660	COG1611	Belongs to the LOG family
IAU62_RS00665	COG1671	Belongs to the UPF0178 family
IAU62_RS00680	COG1968	undecaprenyl-diphosphatase activity
IAU62_RS00685	COG4988	ABC transporter
IAU62_RS00690	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IAU62_RS00710	COG0039	L-malate dehydrogenase activity
IAU62_RS00715	COG0471	metal ion transport
IAU62_RS00720	COG0415	Belongs to the DNA photolyase family
IAU62_RS00745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAU62_RS00750	COG1349	DNA-binding transcription factor activity
IAU62_RS00755	COG1105	Belongs to the carbohydrate kinase PfkB family
IAU62_RS00760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAU62_RS00760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAU62_RS00760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAU62_RS00800	COG1733	regulation of RNA biosynthetic process
IAU62_RS00820	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IAU62_RS00825	COG1253	flavin adenine dinucleotide binding
IAU62_RS00830	COG0656	L-ascorbic acid biosynthetic process
IAU62_RS00835	COG0463	Glycosyl transferase, family 2
IAU62_RS00840	COG5002	protein histidine kinase activity
IAU62_RS00845	COG0745	RESPONSE REGULATOR receiver
IAU62_RS00870	COG0602	queuosine metabolic process
IAU62_RS00875	COG0720	synthase
IAU62_RS00880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IAU62_RS00890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IAU62_RS00905	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IAU62_RS00915	COG1368	sulfuric ester hydrolase activity
IAU62_RS00930	COG0488	(ABC) transporter
IAU62_RS00935	COG0514	ATP-dependent DNA helicase (RecQ)
IAU62_RS00940	COG0517	IMP dehydrogenase activity
IAU62_RS00940	COG1125	glycine betaine transport
IAU62_RS00945	COG1174	glycine betaine transport
IAU62_RS00950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAU62_RS00955	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IAU62_RS00960	COG1454	alcohol dehydrogenase
IAU62_RS00960	COG1012	belongs to the aldehyde dehydrogenase family
IAU62_RS00965	COG1597	lipid kinase activity
IAU62_RS00970	COG3104	oligopeptide transport
IAU62_RS00975	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IAU62_RS00985	COG1780	Probably involved in ribonucleotide reductase function
IAU62_RS00990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAU62_RS00995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IAU62_RS01005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAU62_RS01010	COG4605	iron ion homeostasis
IAU62_RS01015	COG4604	ABC transporter, ATP-binding protein
IAU62_RS01030	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IAU62_RS01050	COG1929	Belongs to the glycerate kinase type-1 family
IAU62_RS01055	COG2195	Cleaves the N-terminal amino acid of tripeptides
IAU62_RS01070	COG2199	diguanylate cyclase activity
IAU62_RS01075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAU62_RS01080	COG1739	Uncharacterized protein family UPF0029
IAU62_RS01090	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IAU62_RS01095	COG1040	competence protein
IAU62_RS01100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAU62_RS01105	COG0653	protein targeting
IAU62_RS01115	COG3942	CHAP domain
IAU62_RS01115	COG1388	LysM domain
IAU62_RS01130	COG0556	nucleotide-excision repair
IAU62_RS01135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IAU62_RS01140	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IAU62_RS01145	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IAU62_RS01160	COG0492	ferredoxin-NADP+ reductase activity
IAU62_RS01165	COG1660	Displays ATPase and GTPase activities
IAU62_RS01170	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IAU62_RS01175	COG1481	regulation of sporulation
IAU62_RS01185	COG0740	serine-type endopeptidase activity
IAU62_RS01195	COG1090	epimerase
IAU62_RS01215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAU62_RS01220	COG0126	phosphoglycerate kinase activity
IAU62_RS01225	COG0149	triose-phosphate isomerase activity
IAU62_RS01230	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IAU62_RS01235	COG0148	phosphopyruvate hydratase activity
IAU62_RS01245	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAU62_RS01250	COG1647	Serine aminopeptidase, S33
IAU62_RS01255	COG0557	exoribonuclease II activity
IAU62_RS01260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IAU62_RS01275	COG0582	viral genome integration into host DNA
IAU62_RS01360	COG5484	DNA packaging
IAU62_RS01360	COG3728	DNA packaging
IAU62_RS01420	COG0110	maltose O-acetyltransferase activity
IAU62_RS01460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAU62_RS01495	COG1278	Cold shock
IAU62_RS01510	COG4195	phage-related replication protein
IAU62_RS01550	COG1764	response to oxidative stress
IAU62_RS01555	COG0710	3-dehydroquinate dehydratase activity
IAU62_RS01565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAU62_RS01570	COG1393	Belongs to the ArsC family
IAU62_RS01575	COG0509	glycine decarboxylation via glycine cleavage system
IAU62_RS01580	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IAU62_RS01590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAU62_RS01595	COG2011	ABC-type metal ion transport system permease component
IAU62_RS01600	COG1464	Belongs to the NlpA lipoprotein family
IAU62_RS01610	COG3237	CsbD-like
IAU62_RS01620	COG0396	ATPase activity
IAU62_RS01625	COG0719	Fe-S assembly protein
IAU62_RS01630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAU62_RS01635	COG0822	iron-sulfur transferase activity
IAU62_RS01640	COG0719	Fe-S assembly protein
IAU62_RS01645	COG4974	Belongs to the 'phage' integrase family
IAU62_RS01655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAU62_RS01740	COG0305	Participates in initiation and elongation during chromosome replication
IAU62_RS01860	COG1783	phage Terminase large subunit
IAU62_RS01940	COG5434	Belongs to the glycosyl hydrolase 28 family
IAU62_RS01995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAU62_RS02010	COG3682	Transcriptional regulator
IAU62_RS02040	COG1253	flavin adenine dinucleotide binding
IAU62_RS02045	COG1801	Protein of unknown function DUF72
IAU62_RS02050	COG0730	response to heat
IAU62_RS02055	COG0737	Belongs to the 5'-nucleotidase family
IAU62_RS02060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IAU62_RS02065	COG4470	Protein conserved in bacteria
IAU62_RS02075	COG2445	Protein of unknown function DUF86
IAU62_RS02080	COG0647	UMP catabolic process
IAU62_RS02095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAU62_RS02100	COG1696	Membrane protein involved in D-alanine export
IAU62_RS02105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAU62_RS02110	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IAU62_RS02115	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IAU62_RS02120	COG4837	Protein of unknown function (DUF1462)
IAU62_RS02125	COG1252	NADH dehydrogenase
IAU62_RS02130	COG4844	belongs to the
IAU62_RS02135	COG0316	Belongs to the HesB IscA family
IAU62_RS02140	COG1252	NADH dehydrogenase
IAU62_RS02145	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IAU62_RS02150	COG2056	Na+-H+ antiporter family
IAU62_RS02155	COG2050	protein possibly involved in aromatic compounds catabolism
IAU62_RS02165	COG1320	monovalent cation:proton antiporter activity
IAU62_RS02170	COG2212	antiporter activity
IAU62_RS02175	COG1863	multisubunit Na H antiporter MnhE subunit
IAU62_RS02180	COG0651	ATP synthesis coupled electron transport
IAU62_RS02185	COG1006	Multisubunit Na H antiporter MnhC subunit
IAU62_RS02190	COG2111	Na H antiporter
IAU62_RS02195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAU62_RS02195	COG2111	Na H antiporter
IAU62_RS02205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IAU62_RS02210	COG1098	S1 RNA binding domain
IAU62_RS02215	COG1902	pentaerythritol trinitrate reductase activity
IAU62_RS02220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAU62_RS02230	COG0584	glycerophosphoryl diester phosphodiesterase
IAU62_RS02235	COG0165	Argininosuccinate lyase
IAU62_RS02240	COG0137	argininosuccinate synthase activity
IAU62_RS02245	COG0166	Belongs to the GPI family
IAU62_RS02255	COG0398	Pfam SNARE associated Golgi protein
IAU62_RS02270	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IAU62_RS02275	COG1074	ATP-dependent DNA helicase activity
IAU62_RS02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAU62_RS02290	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAU62_RS02295	COG0561	phosphatase activity
IAU62_RS02310	COG0542	response to heat
IAU62_RS02330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAU62_RS02345	COG0601	transmembrane transport
IAU62_RS02350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAU62_RS02355	COG0444	Belongs to the ABC transporter superfamily
IAU62_RS02360	COG4608	Belongs to the ABC transporter superfamily
IAU62_RS02365	COG4166	transmembrane transport
IAU62_RS02370	COG0180	Tryptophanyl-tRNA synthetase
IAU62_RS02375	COG1393	Belongs to the ArsC family
IAU62_RS02380	COG4862	establishment of competence for transformation
IAU62_RS02390	COG1164	Oligoendopeptidase f
IAU62_RS02395	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IAU62_RS02400	COG2346	COG2346, Truncated hemoglobins
IAU62_RS02415	COG2357	RelA SpoT domain protein
IAU62_RS02420	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IAU62_RS02425	COG0564	pseudouridine synthase activity
IAU62_RS02430	COG2239	Acts as a magnesium transporter
IAU62_RS02435	COG0475	glutathione-regulated potassium exporter activity
IAU62_RS02435	COG0569	domain protein
IAU62_RS02540	COG0210	DNA helicase
IAU62_RS02545	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IAU62_RS02555	COG1002	Type II restriction enzyme, methylase subunits
IAU62_RS02565	COG0628	permease
IAU62_RS02570	COG2382	esterase
IAU62_RS02575	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IAU62_RS02580	COG2814	Major facilitator Superfamily
IAU62_RS02585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAU62_RS02590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAU62_RS02600	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IAU62_RS02605	COG0861	Integral membrane protein TerC family
IAU62_RS02610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAU62_RS02615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAU62_RS02620	COG0737	Belongs to the 5'-nucleotidase family
IAU62_RS02630	COG4873	Protein conserved in bacteria
IAU62_RS02685	COG1279	arginine transmembrane transporter activity
IAU62_RS02695	COG2314	TM2 domain
IAU62_RS02700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAU62_RS02705	COG1575	Belongs to the MenA family. Type 1 subfamily
IAU62_RS02710	COG1169	isochorismate synthase
IAU62_RS02715	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IAU62_RS02725	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAU62_RS02730	COG0436	Aminotransferase
IAU62_RS02735	COG3594	Acyltransferase
IAU62_RS02760	COG1316	TRANSCRIPTIONal
IAU62_RS02775	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IAU62_RS02780	COG1845	cytochrome c oxidase, subunit III
IAU62_RS02785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAU62_RS02790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IAU62_RS02800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAU62_RS02805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IAU62_RS02810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAU62_RS02815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IAU62_RS02820	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAU62_RS02825	COG0047	phosphoribosylformylglycinamidine synthase activity
IAU62_RS02830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAU62_RS02835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IAU62_RS02840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IAU62_RS02845	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAU62_RS02850	COG0138	bifunctional purine biosynthesis protein purh
IAU62_RS02855	COG0151	Belongs to the GarS family
IAU62_RS02860	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAU62_RS02865	COG4172	Belongs to the ABC transporter superfamily
IAU62_RS02875	COG4716	Myosin-crossreactive antigen
IAU62_RS02885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IAU62_RS02895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAU62_RS02900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAU62_RS02910	COG1271	oxidase subunit
IAU62_RS02915	COG1294	oxidase, subunit
IAU62_RS02920	COG0569	domain protein
IAU62_RS02925	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAU62_RS02930	COG5503	Protein of unknown function (DUF1447)
IAU62_RS02935	COG0242	peptide deformylase activity
IAU62_RS02945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAU62_RS02950	COG0022	dehydrogenase e1 component
IAU62_RS02955	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAU62_RS02965	COG4476	Belongs to the UPF0223 family
IAU62_RS02975	COG3842	ATPase activity
IAU62_RS02980	COG1176	ABC-type spermidine putrescine transport system, permease component I
IAU62_RS03005	COG1914	H( )-stimulated, divalent metal cation uptake system
IAU62_RS03010	COG4493	Belongs to the UPF0637 family
IAU62_RS03015	COG0483	inositol monophosphate 1-phosphatase activity
IAU62_RS03025	COG1217	gtp-binding protein TYPA
IAU62_RS03030	COG4896	Protein conserved in bacteria
IAU62_RS03035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IAU62_RS03040	COG4838	Belongs to the UPF0358 family
IAU62_RS03045	COG0772	Belongs to the SEDS family
IAU62_RS03055	COG1612	heme a metabolic process
IAU62_RS03060	COG0109	protoheme IX farnesyltransferase activity
IAU62_RS03070	COG2340	Cysteine-rich secretory protein family
IAU62_RS03075	COG3679	Belongs to the UPF0342 family
IAU62_RS03080	COG0584	glycerophosphoryl diester phosphodiesterase
IAU62_RS03085	COG4471	UPF0298 protein
IAU62_RS03095	COG0742	ribosomal rna small subunit methyltransferase
IAU62_RS03100	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IAU62_RS03105	COG1323	Belongs to the UPF0348 family
IAU62_RS03115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IAU62_RS03125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAU62_RS03130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAU62_RS03135	COG0072	phenylalanine-tRNA ligase activity
IAU62_RS03135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAU62_RS03140	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAU62_RS03145	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IAU62_RS03155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IAU62_RS03155	COG1796	DNA polymerase
IAU62_RS03160	COG1193	negative regulation of DNA recombination
IAU62_RS03165	COG3118	belongs to the thioredoxin family
IAU62_RS03170	COG0322	excinuclease ABC activity
IAU62_RS03175	COG2009	succinate dehydrogenase
IAU62_RS03180	COG1053	succinate dehydrogenase
IAU62_RS03185	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IAU62_RS03190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IAU62_RS03195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IAU62_RS03230	COG1011	Hydrolase
IAU62_RS03235	COG0454	-acetyltransferase
IAU62_RS03240	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IAU62_RS03245	COG2001	Belongs to the MraZ family
IAU62_RS03250	COG0275	rRNA processing
IAU62_RS03255	COG4839	cell division protein FtsL
IAU62_RS03260	COG0768	penicillin binding
IAU62_RS03265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAU62_RS03270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAU62_RS03280	COG0849	cell division
IAU62_RS03285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAU62_RS03290	COG1496	oxidoreductase activity
IAU62_RS03295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IAU62_RS03300	COG1799	cell septum assembly
IAU62_RS03305	COG0762	integral membrane protein
IAU62_RS03315	COG3599	regulation of cell shape
IAU62_RS03320	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAU62_RS03330	COG1388	LysM domain
IAU62_RS03330	COG3942	CHAP domain
IAU62_RS03335	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IAU62_RS03340	COG0564	pseudouridine synthase activity
IAU62_RS03345	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IAU62_RS03350	COG2233	PERMEase
IAU62_RS03355	COG0540	Belongs to the ATCase OTCase family
IAU62_RS03360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IAU62_RS03365	COG0505	Belongs to the CarA family
IAU62_RS03370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IAU62_RS03375	COG0284	orotidine-5'-phosphate decarboxylase activity
IAU62_RS03380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IAU62_RS03400	COG0194	GDP metabolic process
IAU62_RS03405	COG1758	RNA polymerase activity
IAU62_RS03410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAU62_RS03415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAU62_RS03425	COG0242	peptide deformylase activity
IAU62_RS03430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IAU62_RS03435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IAU62_RS03435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAU62_RS03440	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IAU62_RS03445	COG0631	protein serine/threonine phosphatase activity
IAU62_RS03455	COG1162	GTPase activity
IAU62_RS03460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAU62_RS03470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IAU62_RS03475	COG1302	Protein conserved in bacteria
IAU62_RS03480	COG1461	Dihydroxyacetone kinase
IAU62_RS03485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAU62_RS03490	COG1349	DNA-binding transcription factor activity
IAU62_RS03495	COG0416	fatty acid biosynthetic process
IAU62_RS03505	COG1028	Short-chain dehydrogenase reductase Sdr
IAU62_RS03510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAU62_RS03515	COG0571	ribonuclease III activity
IAU62_RS03520	COG1196	nuclear chromosome segregation
IAU62_RS03525	COG0552	protein localization to endoplasmic reticulum
IAU62_RS03530	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IAU62_RS03535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAU62_RS03540	COG0228	four-way junction DNA binding
IAU62_RS03545	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IAU62_RS03550	COG0336	Belongs to the RNA methyltransferase TrmD family
IAU62_RS03555	COG0335	large ribosomal subunit rRNA binding
IAU62_RS03565	COG4485	Bacterial membrane protein, YfhO
IAU62_RS03575	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAU62_RS03580	COG0045	succinate-CoA ligase (ADP-forming) activity
IAU62_RS03585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAU62_RS03590	COG0758	DNA mediated transformation
IAU62_RS03595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAU62_RS03600	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IAU62_RS03605	COG4974	Belongs to the 'phage' integrase family
IAU62_RS03610	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IAU62_RS03615	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IAU62_RS03620	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IAU62_RS03625	COG0052	Belongs to the universal ribosomal protein uS2 family
IAU62_RS03630	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IAU62_RS03635	COG0528	UMP kinase activity
IAU62_RS03640	COG0233	cytoplasmic translational termination
IAU62_RS03645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAU62_RS03650	COG4589	Belongs to the CDS family
IAU62_RS03660	COG0442	prolyl-tRNA aminoacylation
IAU62_RS03665	COG2176	DNA-directed DNA polymerase activity
IAU62_RS03670	COG0779	Required for maturation of 30S ribosomal subunits
IAU62_RS03675	COG0195	Participates in both transcription termination and antitermination
IAU62_RS03680	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IAU62_RS03685	COG1358	cellular component organization or biogenesis
IAU62_RS03690	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IAU62_RS03695	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IAU62_RS03700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAU62_RS03705	COG0196	riboflavin kinase activity
IAU62_RS03710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IAU62_RS03715	COG1185	polyribonucleotide nucleotidyltransferase activity
IAU62_RS03720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IAU62_RS03725	COG1674	ftsk spoiiie
IAU62_RS03730	COG2188	Transcriptional regulator
IAU62_RS03735	COG0612	Peptidase, M16
IAU62_RS03740	COG0612	Peptidase, M16
IAU62_RS03745	COG0300	oxidoreductase activity
IAU62_RS03760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAU62_RS03765	COG1546	Belongs to the CinA family
IAU62_RS03765	COG1058	Belongs to the CinA family
IAU62_RS03770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IAU62_RS03775	COG1418	mRNA catabolic process
IAU62_RS03785	COG1692	metallophosphoesterase
IAU62_RS03790	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IAU62_RS03790	COG0674	pyruvate-flavodoxin oxidoreductase activity
IAU62_RS03795	COG1013	pyruvate-flavodoxin oxidoreductase activity
IAU62_RS03800	COG4195	phage-related replication protein
IAU62_RS03810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAU62_RS03815	COG4550	Control of competence regulator ComK, YlbF/YmcA
IAU62_RS03825	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IAU62_RS03830	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IAU62_RS03835	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IAU62_RS03840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IAU62_RS03845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAU62_RS03850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IAU62_RS03860	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IAU62_RS03865	COG1923	regulation of RNA biosynthetic process
IAU62_RS03870	COG0386	Belongs to the glutathione peroxidase family
IAU62_RS03875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAU62_RS03880	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IAU62_RS03885	COG0789	Transcriptional regulator
IAU62_RS03890	COG0174	glutamine synthetase
IAU62_RS03940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAU62_RS03945	COG1131	(ABC) transporter
IAU62_RS03960	COG2197	response regulator
IAU62_RS03970	COG1525	nuclease
IAU62_RS03995	COG0527	aspartate kinase activity
IAU62_RS04000	COG0460	homoserine dehydrogenase
IAU62_RS04005	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IAU62_RS04010	COG0083	homoserine kinase activity
IAU62_RS04025	COG0833	amino acid
IAU62_RS04040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAU62_RS04045	COG0516	GMP reductase activity
IAU62_RS04055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAU62_RS04065	COG4224	UPF0291 protein
IAU62_RS04070	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAU62_RS04080	COG4846	Membrane protein involved in cytochrome C biogenesis
IAU62_RS04085	COG0420	3'-5' exonuclease activity
IAU62_RS04090	COG0419	ATPase involved in DNA repair
IAU62_RS04095	COG1970	mechanosensitive ion channel activity
IAU62_RS04100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAU62_RS04105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IAU62_RS04110	COG0824	Thioesterase
IAU62_RS04115	COG4841	protein insertion into membrane
IAU62_RS04120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IAU62_RS04125	COG0187	DNA topoisomerase II activity
IAU62_RS04130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAU62_RS04135	COG1115	amino acid carrier protein
IAU62_RS04140	COG3711	transcriptional antiterminator
IAU62_RS04145	COG0628	permease
IAU62_RS04150	COG0392	lysyltransferase activity
IAU62_RS04150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IAU62_RS04165	COG1942	4-Oxalocrotonate Tautomerase
IAU62_RS04170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAU62_RS04175	COG0287	Prephenate dehydrogenase
IAU62_RS04180	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IAU62_RS04185	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAU62_RS04185	COG0512	Glutamine amidotransferase of anthranilate synthase
IAU62_RS04190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IAU62_RS04195	COG0134	indole-3-glycerol-phosphate synthase activity
IAU62_RS04200	COG0135	phosphoribosylanthranilate isomerase activity
IAU62_RS04205	COG0133	tryptophan synthase activity
IAU62_RS04210	COG0159	tryptophan synthase activity
IAU62_RS04220	COG2348	transferase activity, transferring amino-acyl groups
IAU62_RS04225	COG2348	transferase activity, transferring amino-acyl groups
IAU62_RS04235	COG4607	ABC-type enterochelin transport system periplasmic component
IAU62_RS04265	COG1164	Oligoendopeptidase f
IAU62_RS04270	COG0704	Plays a role in the regulation of phosphate uptake
IAU62_RS04275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAU62_RS04280	COG0581	inorganic phosphate transmembrane transporter activity
IAU62_RS04285	COG0573	inorganic phosphate transmembrane transporter activity
IAU62_RS04290	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAU62_RS04295	COG2996	Protein conserved in bacteria
IAU62_RS04300	COG0488	(ABC) transporter
IAU62_RS04305	COG0527	aspartate kinase activity
IAU62_RS04310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IAU62_RS04315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAU62_RS04320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IAU62_RS04325	COG2171	N-acyltransferase activity
IAU62_RS04330	COG1473	amidohydrolase
IAU62_RS04350	COG1278	Cold shock
IAU62_RS04360	COG1254	Belongs to the acylphosphatase family
IAU62_RS04370	COG3853	Toxic anion resistance protein (TelA)
IAU62_RS04375	COG1114	Component of the transport system for branched-chain amino acids
IAU62_RS04380	COG4548	von Willebrand factor, type A
IAU62_RS04385	COG0714	Associated with various cellular activities
IAU62_RS04405	COG1131	(ABC) transporter
IAU62_RS04410	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAU62_RS04415	COG0567	Dehydrogenase, E1 component
IAU62_RS04420	COG5002	protein histidine kinase activity
IAU62_RS04425	COG0745	RESPONSE REGULATOR receiver
IAU62_RS04430	COG1349	DNA-binding transcription factor activity
IAU62_RS04435	COG0534	Mate efflux family protein
IAU62_RS04445	COG0395	ABC-type sugar transport system, permease component
IAU62_RS04455	COG4209	transmembrane transport
IAU62_RS04460	COG3842	ATPase activity
IAU62_RS04465	COG0671	phosphoesterase, PA-phosphatase related
IAU62_RS04470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAU62_RS04480	COG0793	Belongs to the peptidase S41A family
IAU62_RS04485	COG4479	Belongs to the UPF0346 family
IAU62_RS04490	COG2190	(PTS) system
IAU62_RS04495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAU62_RS04520	COG1136	(ABC) transporter
IAU62_RS04535	COG1413	lyase activity
IAU62_RS04545	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IAU62_RS04555	COG1196	nuclear chromosome segregation
IAU62_RS04555	COG4372	Transposase
IAU62_RS04555	COG1511	domain protein
IAU62_RS04560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAU62_RS04565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IAU62_RS04575	COG0116	Belongs to the methyltransferase superfamily
IAU62_RS04585	COG3599	regulation of cell shape
IAU62_RS04590	COG4474	Belongs to the UPF0398 family
IAU62_RS04600	COG3331	DNA recombination
IAU62_RS04605	COG4499	WXG100 protein secretion system (Wss), protein YukC
IAU62_RS04605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAU62_RS04615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAU62_RS04620	COG3935	DnaD domain protein
IAU62_RS04625	COG0017	Asparaginyl-tRNA synthetase
IAU62_RS04630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAU62_RS04630	COG1199	ATP-dependent helicase activity
IAU62_RS04640	COG0617	tRNA 3'-terminal CCA addition
IAU62_RS04645	COG0438	transferase activity, transferring glycosyl groups
IAU62_RS04650	COG1694	Mazg nucleotide pyrophosphohydrolase
IAU62_RS04655	COG2738	Putative neutral zinc metallopeptidase
IAU62_RS04660	COG4347	Protein of unknown function (DUF1405)
IAU62_RS04665	COG5582	Belongs to the UPF0302 family
IAU62_RS04675	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IAU62_RS04680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IAU62_RS04685	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IAU62_RS04690	COG0105	UTP biosynthetic process
IAU62_RS04695	COG0142	geranyltranstransferase activity
IAU62_RS04700	COG2226	methyltransferase
IAU62_RS04715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IAU62_RS04720	COG1160	GTP binding
IAU62_RS04725	COG0539	negative regulation of cytoplasmic translation
IAU62_RS04730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IAU62_RS04735	COG0252	asparaginase activity
IAU62_RS04740	COG0492	ferredoxin-NADP+ reductase activity
IAU62_RS04745	COG1388	LysM domain
IAU62_RS04750	COG0514	ATP-dependent DNA helicase (RecQ)
IAU62_RS04760	COG1141	Ferredoxin
IAU62_RS04775	COG0745	RESPONSE REGULATOR receiver
IAU62_RS04780	COG1187	pseudouridine synthase activity
IAU62_RS04785	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAU62_RS04790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAU62_RS04795	COG1547	Domain of unknown function (DUF309)
IAU62_RS04800	COG4974	Belongs to the 'phage' integrase family
IAU62_RS04805	COG0735	belongs to the Fur family
IAU62_RS04810	COG0494	nUDIX hydrolase
IAU62_RS04815	COG0667	Aldo Keto reductase
IAU62_RS04820	COG1028	Short-chain dehydrogenase reductase Sdr
IAU62_RS04825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IAU62_RS04830	COG1234	tRNA 3'-trailer cleavage
IAU62_RS04835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IAU62_RS04845	COG0366	Alpha amylase catalytic
IAU62_RS04850	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IAU62_RS04855	COG2195	Cleaves the N-terminal amino acid of tripeptides
IAU62_RS04865	COG4129	membrane
IAU62_RS04875	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAU62_RS04880	COG0022	dehydrogenase e1 component
IAU62_RS04885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAU62_RS04890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAU62_RS04895	COG0497	DNA recombination
IAU62_RS04900	COG1438	arginine binding
IAU62_RS04910	COG1722	exodeoxyribonuclease VII activity
IAU62_RS04915	COG1570	exodeoxyribonuclease VII activity
IAU62_RS04920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAU62_RS04925	COG1302	Protein conserved in bacteria
IAU62_RS04930	COG0439	Biotin carboxylase
IAU62_RS04935	COG0511	ligase activity, forming carbon-carbon bonds
IAU62_RS04940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAU62_RS04945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IAU62_RS04950	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IAU62_RS04955	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IAU62_RS04960	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAU62_RS04965	COG0006	proline dipeptidase activity
IAU62_RS04980	COG0095	Lipoate-protein ligase
IAU62_RS04985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAU62_RS04995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IAU62_RS05000	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IAU62_RS05005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IAU62_RS05010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAU62_RS05030	COG4537	Required for transformation and DNA binding
IAU62_RS05035	COG1459	type II secretion system
IAU62_RS05040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAU62_RS05045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAU62_RS05050	COG0011	TIGRFAM Protein of
IAU62_RS05055	COG1940	carbohydrate kinase activity
IAU62_RS05060	COG4483	Protein conserved in bacteria
IAU62_RS05065	COG0457	Tetratricopeptide repeat
IAU62_RS05065	COG0705	Rhomboid family
IAU62_RS05070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAU62_RS05075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IAU62_RS05080	COG0768	penicillin binding
IAU62_RS05085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAU62_RS05090	COG0735	belongs to the Fur family
IAU62_RS05095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IAU62_RS05100	COG1121	(ABC) transporter
IAU62_RS05105	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IAU62_RS05110	COG0513	Belongs to the DEAD box helicase family
IAU62_RS05115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAU62_RS05120	COG2384	SAM-dependent methyltransferase
IAU62_RS05125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAU62_RS05130	COG0358	DNA primase activity
IAU62_RS05135	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IAU62_RS05140	COG0517	IMP dehydrogenase activity
IAU62_RS05145	COG0423	glycine-tRNA ligase activity
IAU62_RS05150	COG1381	Involved in DNA repair and RecF pathway recombination
IAU62_RS05155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAU62_RS05160	COG0295	cytidine deaminase activity
IAU62_RS05165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IAU62_RS05170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IAU62_RS05175	COG1702	phosphate starvation-inducible protein PhoH
IAU62_RS05185	COG4864	UPF0365 protein
IAU62_RS05190	COG1030	water channel activity
IAU62_RS05200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAU62_RS05205	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAU62_RS05210	COG2264	protein methyltransferase activity
IAU62_RS05215	COG0484	heat shock protein binding
IAU62_RS05220	COG0443	Heat shock 70 kDa protein
IAU62_RS05225	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IAU62_RS05230	COG1420	regulation of RNA biosynthetic process
IAU62_RS05235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAU62_RS05240	COG0481	GTPase activity
IAU62_RS05245	COG0268	Binds directly to 16S ribosomal RNA
IAU62_RS05255	COG1466	dna polymerase III delta subunit
IAU62_RS05265	COG2131	deaminase
IAU62_RS05275	COG2226	methyltransferase
IAU62_RS05280	COG0799	negative regulation of ribosome biogenesis
IAU62_RS05285	COG1713	HD superfamily hydrolase involved in NAD metabolism
IAU62_RS05290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IAU62_RS05295	COG1534	Rna-binding protein
IAU62_RS05300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IAU62_RS05305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IAU62_RS05310	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IAU62_RS05315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAU62_RS05320	COG1914	H( )-stimulated, divalent metal cation uptake system
IAU62_RS05325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IAU62_RS05330	COG0439	Biotin carboxylase
IAU62_RS05335	COG0511	ligase activity, forming carbon-carbon bonds
IAU62_RS05340	COG1984	allophanate hydrolase subunit 2
IAU62_RS05345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IAU62_RS05350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAU62_RS05355	COG0572	uridine kinase
IAU62_RS05360	COG0826	peptidase U32
IAU62_RS05365	COG0826	peptidase U32
IAU62_RS05375	COG3906	Belongs to the UPF0473 family
IAU62_RS05380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IAU62_RS05385	COG4472	Bacterial protein of unknown function (DUF965)
IAU62_RS05390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IAU62_RS05395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAU62_RS05405	COG0482	sulfurtransferase activity
IAU62_RS05410	COG1104	cysteine desulfurase activity
IAU62_RS05415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAU62_RS05430	COG1959	2 iron, 2 sulfur cluster binding
IAU62_RS05435	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IAU62_RS05440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IAU62_RS05450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IAU62_RS05455	COG0124	histidyl-tRNA synthetase
IAU62_RS05460	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAU62_RS05465	COG1490	D-aminoacyl-tRNA deacylase activity
IAU62_RS05470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAU62_RS05475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAU62_RS05480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IAU62_RS05480	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IAU62_RS05485	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAU62_RS05485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAU62_RS05490	COG1862	Preprotein translocase
IAU62_RS05495	COG0343	queuine tRNA-ribosyltransferase activity
IAU62_RS05500	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IAU62_RS05505	COG2255	four-way junction helicase activity
IAU62_RS05510	COG0632	four-way junction helicase activity
IAU62_RS05515	COG4492	Belongs to the UPF0735 family
IAU62_RS05520	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IAU62_RS05525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IAU62_RS05530	COG2868	ribosomal protein
IAU62_RS05535	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IAU62_RS05565	COG2003	Belongs to the UPF0758 family
IAU62_RS05575	COG0285	dihydrofolate synthase activity
IAU62_RS05580	COG0525	valine-tRNA ligase activity
IAU62_RS05585	COG2818	Glycosylase
IAU62_RS05595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IAU62_RS05600	COG0113	porphobilinogen synthase activity
IAU62_RS05610	COG0181	hydroxymethylbilane synthase activity
IAU62_RS05620	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IAU62_RS05625	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IAU62_RS05630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IAU62_RS05635	COG0544	peptidyl-prolyl cis-trans isomerase activity
IAU62_RS05645	COG4112	unkown
IAU62_RS05650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IAU62_RS05655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IAU62_RS05660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAU62_RS05665	COG0833	amino acid
IAU62_RS05670	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAU62_RS05675	COG1484	DNA-dependent DNA replication
IAU62_RS05680	COG3611	Membrane attachment protein
IAU62_RS05685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IAU62_RS05695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAU62_RS05705	COG0237	dephospho-CoA kinase activity
IAU62_RS05710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IAU62_RS05715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAU62_RS05715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IAU62_RS05720	COG5002	protein histidine kinase activity
IAU62_RS05725	COG0745	RESPONSE REGULATOR receiver
IAU62_RS05730	COG0538	isocitrate dehydrogenase activity
IAU62_RS05735	COG0372	Belongs to the citrate synthase family
IAU62_RS05740	COG1113	amino acid transport
IAU62_RS05745	COG0469	pyruvate kinase activity
IAU62_RS05750	COG0205	6-phosphofructokinase activity
IAU62_RS05755	COG0825	malonyl-CoA metabolic process
IAU62_RS05760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IAU62_RS05765	COG0281	malic enzyme
IAU62_RS05770	COG0587	DNA-directed DNA polymerase activity
IAU62_RS05775	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IAU62_RS05780	COG4109	DRTGG domain
IAU62_RS05790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IAU62_RS05795	COG0006	proline dipeptidase activity
IAU62_RS05800	COG0686	Belongs to the AlaDH PNT family
IAU62_RS05805	COG0589	response to stress
IAU62_RS05810	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAU62_RS05815	COG0827	DNA restriction-modification system
IAU62_RS05820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IAU62_RS05830	COG0301	tRNA thio-modification
IAU62_RS05840	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IAU62_RS05845	COG1956	GAF domain-containing protein
IAU62_RS05850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IAU62_RS05855	COG0584	glycerophosphoryl diester phosphodiesterase
IAU62_RS05860	COG1764	response to oxidative stress
IAU62_RS05865	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IAU62_RS05870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAU62_RS05880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAU62_RS05880	COG1263	PTS System
IAU62_RS05885	COG0204	Acyl-transferase
IAU62_RS05890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAU62_RS05895	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IAU62_RS05905	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IAU62_RS05910	COG1609	Transcriptional regulator
IAU62_RS05915	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IAU62_RS05915	COG1605	Chorismate mutase
IAU62_RS05925	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IAU62_RS05930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAU62_RS05935	COG1674	ftsk spoiiie
IAU62_RS05940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAU62_RS05945	COG4848	Belongs to the UPF0354 family
IAU62_RS05950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAU62_RS05955	COG1363	Peptidase, m42
IAU62_RS05965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IAU62_RS05970	COG0510	thiamine kinase activity
IAU62_RS05975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAU62_RS05980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAU62_RS05990	COG1187	pseudouridine synthase activity
IAU62_RS05995	COG2244	polysaccharide biosynthetic process
IAU62_RS06000	COG2081	HI0933 family
IAU62_RS06015	COG0495	leucyl-tRNA aminoacylation
IAU62_RS06020	COG2814	Major facilitator Superfamily
IAU62_RS06025	COG1242	4 iron, 4 sulfur cluster binding
IAU62_RS06030	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IAU62_RS06040	COG2267	carboxylic ester hydrolase activity
IAU62_RS06045	COG0506	proline dehydrogenase activity
IAU62_RS06050	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IAU62_RS06055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAU62_RS06055	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IAU62_RS06065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAU62_RS06065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAU62_RS06075	COG3266	domain, Protein
IAU62_RS06075	COG4193	domain, Protein
IAU62_RS06075	COG5632	N-Acetylmuramoyl-L-alanine amidase
IAU62_RS06100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAU62_RS06110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAU62_RS06115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAU62_RS06120	COG0656	L-ascorbic acid biosynthetic process
IAU62_RS06130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IAU62_RS06135	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IAU62_RS06140	COG1506	peptidase
IAU62_RS06145	COG0494	nUDIX hydrolase
IAU62_RS06150	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IAU62_RS06160	COG0318	PFAM AMP-dependent synthetase and ligase
IAU62_RS06225	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IAU62_RS06230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IAU62_RS06235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IAU62_RS06240	COG2329	Antibiotic biosynthesis monooxygenase
IAU62_RS06250	COG4473	ABC transporter
IAU62_RS06255	COG1131	(ABC) transporter
IAU62_RS06260	COG0537	adenosine 5'-monophosphoramidase activity
IAU62_RS06275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAU62_RS06285	COG3481	metal-dependent phosphohydrolase, HD sub domain
IAU62_RS06295	COG0420	3'-5' exonuclease activity
IAU62_RS06300	COG3679	Belongs to the UPF0342 family
IAU62_RS06305	COG4399	Belongs to the UPF0754 family
IAU62_RS06315	COG2197	response regulator
IAU62_RS06320	COG2203	Gaf domain
IAU62_RS06320	COG4585	Histidine kinase
IAU62_RS06325	COG0564	pseudouridine synthase activity
IAU62_RS06335	COG0114	fumarate hydratase activity
IAU62_RS06360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IAU62_RS06365	COG1126	abc transporter atp-binding protein
IAU62_RS06370	COG0765	amino acid transport
IAU62_RS06540	COG0735	belongs to the Fur family
IAU62_RS06545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAU62_RS06550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IAU62_RS06555	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IAU62_RS06560	COG4129	membrane
IAU62_RS06570	COG3557	Belongs to the UPF0374 family
IAU62_RS06580	COG1988	membrane-bound metal-dependent
IAU62_RS06590	COG1388	LysM domain
IAU62_RS06590	COG1134	teichoic acid transport
IAU62_RS06600	COG2137	regulation of response to DNA damage stimulus
IAU62_RS06605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAU62_RS06610	COG0693	protein deglycase activity
IAU62_RS06620	COG0535	radical SAM domain protein
IAU62_RS06625	COG1607	acyl-coa hydrolase
IAU62_RS06630	COG2309	aminopeptidase activity
IAU62_RS06635	COG4840	Belongs to the UPF0435 family
IAU62_RS06640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAU62_RS06650	COG1295	ribonuclease BN
IAU62_RS06655	COG2197	response regulator
IAU62_RS06660	COG4585	Histidine kinase
IAU62_RS06675	COG0024	Methionine aminopeptidase
IAU62_RS06680	COG4129	membrane
IAU62_RS06700	COG1528	Iron-storage protein
IAU62_RS06710	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IAU62_RS06720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAU62_RS06725	COG1597	lipid kinase activity
IAU62_RS06730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAU62_RS06735	COG0154	amidase activity
IAU62_RS06740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAU62_RS06745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAU62_RS06750	COG4851	CamS sex pheromone cAM373 precursor
IAU62_RS06755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAU62_RS06760	COG0210	DNA helicase
IAU62_RS06765	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IAU62_RS06770	COG4496	protein, YerC YecD
IAU62_RS06775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IAU62_RS06785	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
IAU62_RS06790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IAU62_RS06795	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IAU62_RS06805	COG0077	Prephenate dehydratase
IAU62_RS06820	COG1335	isochorismatase
IAU62_RS06825	COG1227	inorganic diphosphatase activity
IAU62_RS06830	COG1012	belongs to the aldehyde dehydrogenase family
IAU62_RS06835	COG2706	6-phosphogluconolactonase activity
IAU62_RS06880	COG1131	(ABC) transporter
IAU62_RS06890	COG1131	(ABC) transporter
IAU62_RS06895	COG1725	Transcriptional regulator
IAU62_RS06940	COG0582	viral genome integration into host DNA
IAU62_RS06945	COG0459	protein refolding
IAU62_RS06950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IAU62_RS06985	COG3290	protein histidine kinase activity
IAU62_RS06990	COG3279	Response regulator of the LytR AlgR family
IAU62_RS06995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAU62_RS07000	COG1621	beta-fructofuranosidase activity
IAU62_RS07005	COG1609	Transcriptional regulator
IAU62_RS07010	COG0004	ammonium transporteR
IAU62_RS07015	COG0425	Belongs to the sulfur carrier protein TusA family
IAU62_RS07020	COG2391	methyltransferase activity
IAU62_RS07030	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IAU62_RS07035	COG0488	(ABC) transporter
IAU62_RS07040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IAU62_RS07045	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAU62_RS07050	COG0456	acetyltransferase
IAU62_RS07055	COG1214	PFAM Peptidase M22, glycoprotease
IAU62_RS07060	COG0802	atpase or kinase
IAU62_RS07065	COG0129	dihydroxy-acid dehydratase activity
IAU62_RS07070	COG0028	Belongs to the TPP enzyme family
IAU62_RS07080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IAU62_RS07085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAU62_RS07090	COG0473	3-isopropylmalate dehydrogenase activity
IAU62_RS07095	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IAU62_RS07100	COG0066	3-isopropylmalate dehydratase activity
IAU62_RS07105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAU62_RS07135	COG3091	SprT-like family
IAU62_RS07140	COG2183	response to ionizing radiation
IAU62_RS07145	COG1191	sigma factor activity
IAU62_RS07160	COG2208	phosphoserine phosphatase activity
IAU62_RS07165	COG2337	Toxic component of a toxin-antitoxin (TA) module
IAU62_RS07175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAU62_RS07180	COG0736	holo-[acyl-carrier-protein] synthase activity
IAU62_RS07185	COG3402	PFAM membrane-flanked domain
IAU62_RS07190	COG3428	Bacterial PH domain
IAU62_RS07200	COG0513	Belongs to the DEAD box helicase family
IAU62_RS07205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IAU62_RS07210	COG1181	Belongs to the D-alanine--D-alanine ligase family
IAU62_RS07215	COG0772	Belongs to the SEDS family
IAU62_RS07230	COG1937	Protein conserved in bacteria
IAU62_RS07235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAU62_RS07240	COG1418	mRNA catabolic process
IAU62_RS07245	COG0706	membrane insertase activity
IAU62_RS07250	COG0352	thiamine-phosphate diphosphorylase activity
IAU62_RS07255	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IAU62_RS07265	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAU62_RS07270	COG1388	LysM domain
IAU62_RS07275	COG0629	single-stranded DNA binding
IAU62_RS07285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IAU62_RS07290	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAU62_RS07300	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IAU62_RS07305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IAU62_RS07310	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IAU62_RS07315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IAU62_RS07320	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAU62_RS07325	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IAU62_RS07335	COG0356	it plays a direct role in the translocation of protons across the membrane
IAU62_RS07345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IAU62_RS07350	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IAU62_RS07355	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAU62_RS07360	COG4475	Protein of unknown function (DUF436)
IAU62_RS07365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAU62_RS07370	COG0009	L-threonylcarbamoyladenylate synthase
IAU62_RS07375	COG2890	protein-(glutamine-N5) methyltransferase activity
IAU62_RS07380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAU62_RS07385	COG1435	thymidine kinase activity
IAU62_RS07390	COG0254	rRNA binding
IAU62_RS07395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IAU62_RS07400	COG1012	belongs to the aldehyde dehydrogenase family
IAU62_RS07410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAU62_RS07415	COG0191	fructose-bisphosphate aldolase activity
IAU62_RS07425	COG0504	CTP synthase activity
IAU62_RS07430	COG3343	RNA polymerase activity
IAU62_RS07435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAU62_RS07440	COG5146	pantothenate kinase activity
IAU62_RS07460	COG1854	S-ribosylhomocysteine lyase activity
IAU62_RS07470	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IAU62_RS07475	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IAU62_RS07480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IAU62_RS07485	COG0813	purine-nucleoside phosphorylase activity
IAU62_RS07490	COG0783	Belongs to the Dps family
IAU62_RS07510	COG1482	cell wall glycoprotein biosynthetic process
IAU62_RS07515	COG0702	epimerase
IAU62_RS07520	COG0640	Transcriptional regulator
IAU62_RS07540	COG0561	phosphatase activity
IAU62_RS07545	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IAU62_RS07550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAU62_RS07560	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IAU62_RS07610	COG0489	protein tyrosine kinase activity
IAU62_RS07615	COG2814	Major facilitator Superfamily
IAU62_RS07635	COG4284	Utp--glucose-1-phosphate uridylyltransferase
IAU62_RS07640	COG1988	membrane-bound metal-dependent
IAU62_RS07650	COG2329	Antibiotic biosynthesis monooxygenase
IAU62_RS07655	COG3314	Sporulation integral membrane protein YlbJ
IAU62_RS07660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAU62_RS07665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAU62_RS07670	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IAU62_RS07675	COG3457	Alanine racemase
IAU62_RS07680	COG4264	IucA IucC family
IAU62_RS07685	COG2814	Major facilitator Superfamily
IAU62_RS07690	COG4264	IucA IucC family
IAU62_RS07695	COG1302	Protein conserved in bacteria
IAU62_RS07710	COG0604	alcohol dehydrogenase
IAU62_RS07715	COG2130	NADP-dependent
IAU62_RS07720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAU62_RS07730	COG2723	6-phospho-beta-galactosidase activity
IAU62_RS07735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAU62_RS07735	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IAU62_RS07740	COG1447	Phosphotransferase system cellobiose-specific component IIA
IAU62_RS07745	COG3684	Belongs to the aldolase LacD family
IAU62_RS07750	COG1105	Belongs to the carbohydrate kinase PfkB family
IAU62_RS07755	COG0698	ribose 5-phosphate isomerase
IAU62_RS07760	COG0698	ribose 5-phosphate isomerase
IAU62_RS07765	COG1349	DNA-binding transcription factor activity
IAU62_RS07770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IAU62_RS07775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IAU62_RS07780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IAU62_RS07785	COG0101	tRNA pseudouridine synthase activity
IAU62_RS07795	COG1122	ATPase activity
IAU62_RS07800	COG1122	ATPase activity
IAU62_RS07805	COG0203	ribosomal protein L17
IAU62_RS07810	COG0202	RNA polymerase activity
IAU62_RS07815	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IAU62_RS07820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IAU62_RS07825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IAU62_RS07830	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IAU62_RS07835	COG0563	adenylate kinase activity
IAU62_RS07840	COG0201	protein transport
IAU62_RS07845	COG0200	Binds to the 23S rRNA
IAU62_RS07850	COG1841	ribosomal large subunit assembly
IAU62_RS07855	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IAU62_RS07860	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IAU62_RS07865	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IAU62_RS07870	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IAU62_RS07875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAU62_RS07880	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IAU62_RS07885	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IAU62_RS07890	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IAU62_RS07895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IAU62_RS07905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IAU62_RS07910	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IAU62_RS07915	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IAU62_RS07920	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IAU62_RS07925	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IAU62_RS07930	COG0089	rRNA binding
IAU62_RS07935	COG0088	Forms part of the polypeptide exit tunnel
IAU62_RS07940	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IAU62_RS07955	COG2252	PERMEase
IAU62_RS07960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAU62_RS07960	COG0551	DNA topoisomerase type I activity
IAU62_RS07965	COG4975	Glucose uptake
IAU62_RS07970	COG1028	Short-chain dehydrogenase reductase Sdr
IAU62_RS07990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAU62_RS07995	COG2348	transferase activity, transferring amino-acyl groups
IAU62_RS08015	COG2814	Major facilitator Superfamily
IAU62_RS08025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAU62_RS08030	COG0746	molybdenum cofactor guanylyltransferase activity
IAU62_RS08040	COG0314	molybdopterin synthase activity
IAU62_RS08050	COG0303	'Molybdopterin
IAU62_RS08055	COG0315	cyclic pyranopterin monophosphate synthase activity
IAU62_RS08060	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAU62_RS08065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAU62_RS08070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IAU62_RS08075	COG4149	molybdate abc transporter
IAU62_RS08080	COG0725	ABC transporter, periplasmic molybdate-binding protein
IAU62_RS08085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IAU62_RS08095	COG1268	BioY protein
IAU62_RS08105	COG1960	acyl-CoA dehydrogenase activity
IAU62_RS08115	COG0831	urea catabolic process
IAU62_RS08120	COG0832	Belongs to the urease beta subunit family
IAU62_RS08125	COG0804	urea catabolic process
IAU62_RS08130	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IAU62_RS08135	COG0830	nickel cation binding
IAU62_RS08140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IAU62_RS08145	COG0829	nickel cation binding
IAU62_RS08170	COG3942	CHAP domain
IAU62_RS08175	COG1757	Na H antiporter
IAU62_RS08190	COG3942	CHAP domain
IAU62_RS08195	COG2076	Multidrug Resistance protein
IAU62_RS08200	COG2076	Multidrug Resistance protein
IAU62_RS08205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAU62_RS08240	COG1316	TRANSCRIPTIONal
IAU62_RS08245	COG0483	inositol monophosphate 1-phosphatase activity
IAU62_RS08255	COG1266	CAAX protease self-immunity
IAU62_RS08270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IAU62_RS08275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAU62_RS08275	COG1263	PTS System
IAU62_RS08285	COG1113	amino acid transport
IAU62_RS08305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAU62_RS08315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAU62_RS08315	COG1263	PTS System
IAU62_RS08320	COG1737	Transcriptional regulator
IAU62_RS08340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAU62_RS08345	COG1028	Short-chain dehydrogenase reductase Sdr
IAU62_RS08350	COG1473	amidohydrolase
IAU62_RS08355	COG0010	Belongs to the arginase family
IAU62_RS08360	COG1266	CAAX protease self-immunity
IAU62_RS08370	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IAU62_RS08375	COG2258	MOSC domain
IAU62_RS08380	COG2017	converts alpha-aldose to the beta-anomer
IAU62_RS08385	COG1069	ribulokinase activity
IAU62_RS08395	COG2094	Belongs to the DNA glycosylase MPG family
IAU62_RS08415	COG0786	glutamate:sodium symporter activity
IAU62_RS08420	COG1304	FMN binding
IAU62_RS08425	COG0598	Magnesium transport protein CorA
IAU62_RS08440	COG0657	acetylesterase activity
IAU62_RS08450	COG2814	Major facilitator Superfamily
IAU62_RS08455	COG1566	PFAM secretion protein HlyD family protein
IAU62_RS08465	COG2814	Major facilitator Superfamily
IAU62_RS08470	COG4640	response to antibiotic
IAU62_RS08485	COG1136	(ABC) transporter
IAU62_RS08490	COG0577	efflux transmembrane transporter activity
IAU62_RS08495	COG0745	RESPONSE REGULATOR receiver
IAU62_RS08500	COG5002	protein histidine kinase activity
IAU62_RS08500	COG3850	Histidine kinase
IAU62_RS08505	COG0579	oxidoreductase
IAU62_RS08515	COG1620	l-lactate permease
IAU62_RS08520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAU62_RS08520	COG0463	Glycosyl transferase, family 2
IAU62_RS08530	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAU62_RS08530	COG0463	Glycosyl transferase, family 2
IAU62_RS08535	COG0456	acetyltransferase
IAU62_RS08540	COG0604	alcohol dehydrogenase
IAU62_RS08570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAU62_RS08570	COG1263	PTS System
IAU62_RS08585	COG3871	stress protein (general stress protein 26)
IAU62_RS08605	COG0778	Nitroreductase
IAU62_RS08610	COG1846	Transcriptional regulator
IAU62_RS08615	COG2223	nitrite transmembrane transporter activity
IAU62_RS08620	COG2197	response regulator
IAU62_RS08625	COG4585	Histidine kinase
IAU62_RS08635	COG2181	nitrate reductase activity
IAU62_RS08645	COG1140	nitrate reductase beta subunit
IAU62_RS08660	COG2146	nitrite reductase [NAD(P)H] activity
IAU62_RS08665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAU62_RS08680	COG0747	negative chemotaxis
IAU62_RS08690	COG0454	-acetyltransferase
IAU62_RS08695	COG2116	formate transmembrane transporter activity
IAU62_RS08715	COG2348	transferase activity, transferring amino-acyl groups
IAU62_RS08720	COG1126	abc transporter atp-binding protein
IAU62_RS08725	COG0765	amino acid transport
IAU62_RS08730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAU62_RS08740	COG0588	phosphoglycerate mutase activity
IAU62_RS08745	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IAU62_RS08760	COG1929	Belongs to the glycerate kinase type-1 family
IAU62_RS08785	COG1113	amino acid transport
IAU62_RS08790	COG0531	amino acid
IAU62_RS08800	COG0706	membrane insertase activity
IAU62_RS08805	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAU62_RS08815	COG3275	phosphorelay sensor kinase activity
IAU62_RS08820	COG3279	Response regulator of the LytR AlgR family
IAU62_RS08825	COG1380	Effector of murein hydrolase LrgA
IAU62_RS08830	COG1346	cytolysis
IAU62_RS08835	COG1174	glycine betaine transport
IAU62_RS08855	COG1063	alcohol dehydrogenase
IAU62_RS08860	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
IAU62_RS08865	COG0531	amino acid
IAU62_RS08870	COG2272	Belongs to the type-B carboxylesterase lipase family
IAU62_RS08875	COG2814	Major facilitator Superfamily
IAU62_RS08880	COG0390	transport system, permease component
IAU62_RS08885	COG4619	ABC transporter
IAU62_RS08900	COG0069	glutamate synthase activity
IAU62_RS08910	COG1363	Peptidase, m42
IAU62_RS08920	COG1028	Short-chain dehydrogenase reductase Sdr
IAU62_RS08930	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IAU62_RS08935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAU62_RS08940	COG4221	oxidoreductase activity
IAU62_RS08965	COG0438	transferase activity, transferring glycosyl groups
IAU62_RS08970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAU62_RS08975	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IAU62_RS08980	COG2610	gluconate transmembrane transporter activity
IAU62_RS08990	COG1802	Transcriptional regulator
IAU62_RS08995	COG2271	Major facilitator Superfamily
IAU62_RS09000	COG0789	Transcriptional regulator
IAU62_RS09015	COG2357	RelA SpoT domain protein
IAU62_RS09020	COG4876	unkown
IAU62_RS09035	COG2271	Major facilitator Superfamily
IAU62_RS09045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAU62_RS09055	COG2022	thiamine diphosphate biosynthetic process
IAU62_RS09060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAU62_RS09065	COG0586	Pfam SNARE associated Golgi protein
IAU62_RS09070	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
IAU62_RS09080	COG3949	Membrane
IAU62_RS09085	COG1012	belongs to the aldehyde dehydrogenase family
IAU62_RS09100	COG2514	catechol 2,3-dioxygenase activity
IAU62_RS09110	COG1012	belongs to the aldehyde dehydrogenase family
IAU62_RS09115	COG0778	Nitroreductase
IAU62_RS09120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAU62_RS09130	COG3764	Sortase (surface protein transpeptidase)
IAU62_RS09145	COG1760	l-serine dehydratase
IAU62_RS09150	COG1760	l-serine dehydratase
IAU62_RS09165	COG1070	Carbohydrate kinase
IAU62_RS09175	COG1869	D-ribose catabolic process
IAU62_RS09180	COG4975	Glucose uptake
IAU62_RS09195	COG2843	Capsule synthesis protein
IAU62_RS09205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAU62_RS09220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IAU62_RS09225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAU62_RS09230	COG1063	alcohol dehydrogenase
IAU62_RS09235	COG1266	CAAX protease self-immunity
IAU62_RS09240	COG2190	(PTS) system
IAU62_RS09240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IAU62_RS09240	COG1263	PTS System
IAU62_RS09245	COG0028	Belongs to the TPP enzyme family
IAU62_RS09250	COG1346	cytolysis
IAU62_RS09255	COG1380	Effector of murein hydrolase LrgA
IAU62_RS09260	COG0583	DNA-binding transcription factor activity
IAU62_RS09280	COG3425	synthase
IAU62_RS09285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAU62_RS09310	COG1012	belongs to the aldehyde dehydrogenase family
IAU62_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
IAU62_RS09325	COG2217	Heavy metal translocating P-type atpase
IAU62_RS09330	COG2608	mercury ion transmembrane transporter activity
IAU62_RS09340	COG0436	Aminotransferase
IAU62_RS09345	COG3942	CHAP domain
IAU62_RS09355	COG0741	lytic transglycosylase activity
IAU62_RS09370	COG1113	amino acid transport
IAU62_RS09375	COG3001	Fructosamine kinase
IAU62_RS09380	COG0167	dihydroorotate dehydrogenase activity
IAU62_RS09390	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IAU62_RS09405	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IAU62_RS09410	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IAU62_RS09415	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IAU62_RS09425	COG3527	Alpha-acetolactate decarboxylase
IAU62_RS09430	COG0028	Belongs to the TPP enzyme family
IAU62_RS09435	COG0039	L-malate dehydrogenase activity
IAU62_RS09440	COG0583	DNA-binding transcription factor activity
IAU62_RS09445	COG0531	amino acid
IAU62_RS09475	COG0446	pyridine nucleotide-disulphide oxidoreductase
IAU62_RS09480	COG3588	fructose-bisphosphate aldolase
IAU62_RS09490	COG0579	oxidoreductase
IAU62_RS09495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IAU62_RS09500	COG0574	Belongs to the PEP-utilizing enzyme family
IAU62_RS09500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAU62_RS09505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAU62_RS09520	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IAU62_RS09525	COG1012	belongs to the aldehyde dehydrogenase family
IAU62_RS09530	COG1510	regulation of RNA biosynthetic process
IAU62_RS09540	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IAU62_RS09545	COG0602	queuosine metabolic process
IAU62_RS09550	COG1328	CTP reductase activity
IAU62_RS09560	COG0529	Catalyzes the synthesis of activated sulfate
IAU62_RS09565	COG2046	Belongs to the sulfate adenylyltransferase family
IAU62_RS09570	COG0730	response to heat
IAU62_RS09585	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAU62_RS09590	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IAU62_RS09595	COG0175	sulfate reduction
IAU62_RS09600	COG0386	Belongs to the glutathione peroxidase family
IAU62_RS09605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAU62_RS09610	COG1846	Transcriptional regulator
IAU62_RS09650	COG1136	(ABC) transporter
IAU62_RS09655	COG2205	protein histidine kinase activity
IAU62_RS09670	COG1785	Belongs to the alkaline phosphatase family
IAU62_RS09675	COG0702	epimerase
IAU62_RS09680	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IAU62_RS09690	COG4195	phage-related replication protein
IAU62_RS09815	COG1388	LysM domain
IAU62_RS09815	COG3942	CHAP domain
IAU62_RS09830	COG3961	Belongs to the TPP enzyme family
IAU62_RS09835	COG2843	Capsule synthesis protein
IAU62_RS09845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAU62_RS09860	COG2235	arginine
IAU62_RS09865	COG1438	arginine binding
IAU62_RS09870	COG3227	Zinc metalloprotease (Elastase)
IAU62_RS09905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAU62_RS09905	COG3711	transcriptional antiterminator
IAU62_RS09910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAU62_RS09910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAU62_RS09910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IAU62_RS09915	COG1482	cell wall glycoprotein biosynthetic process
IAU62_RS09925	COG3942	CHAP domain
IAU62_RS09925	COG1705	Flagellar rod assembly protein muramidase FlgJ
IAU62_RS09935	COG1764	response to oxidative stress
IAU62_RS09945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAU62_RS09950	COG2814	Major facilitator Superfamily
IAU62_RS09980	COG0653	protein targeting
IAU62_RS10005	COG3639	organic phosphonate transmembrane transporter activity
IAU62_RS10010	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IAU62_RS10025	COG0737	Belongs to the 5'-nucleotidase family
IAU62_RS10030	COG2814	Major facilitator Superfamily
IAU62_RS10050	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IAU62_RS10055	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IAU62_RS10060	COG0140	phosphoribosyl-ATP diphosphatase activity
IAU62_RS10060	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IAU62_RS10065	COG0107	imidazoleglycerol-phosphate synthase activity
IAU62_RS10070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IAU62_RS10075	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAU62_RS10080	COG0131	Imidazoleglycerol-phosphate dehydratase
IAU62_RS10085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAU62_RS10090	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IAU62_RS10095	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IAU62_RS10120	COG0579	oxidoreductase
IAU62_RS10125	COG2353	YceI-like domain
IAU62_RS10130	COG3386	PFAM SMP-30 Gluconolaconase
IAU62_RS10135	COG1054	Belongs to the UPF0176 family
IAU62_RS10140	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IAU62_RS10160	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAU62_RS10165	COG0022	dehydrogenase e1 component
IAU62_RS10170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAU62_RS10175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAU62_RS10180	COG0471	metal ion transport
IAU62_RS10185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAU62_RS10190	COG2962	Rard protein
IAU62_RS10205	COG2814	Major facilitator Superfamily
IAU62_RS10230	COG2814	Major facilitator Superfamily
IAU62_RS10250	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IAU62_RS10255	COG1461	Dihydroxyacetone kinase
IAU62_RS10260	COG2376	Dihydroxyacetone kinase
IAU62_RS10270	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IAU62_RS10275	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
IAU62_RS10290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IAU62_RS10295	COG0549	Belongs to the carbamate kinase family
IAU62_RS10300	COG1288	antiporter activity
IAU62_RS10335	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAU62_RS10340	COG3246	L-lysine catabolic process to acetate
IAU62_RS10345	COG1309	transcriptional regulator
IAU62_RS10350	COG1114	Component of the transport system for branched-chain amino acids
IAU62_RS10355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAU62_RS10360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IAU62_RS10365	COG1882	Formate acetyltransferase
IAU62_RS10375	COG1124	(ABC) transporter
IAU62_RS10380	COG0444	Belongs to the ABC transporter superfamily
IAU62_RS10390	COG0601	transmembrane transport
IAU62_RS10440	COG1028	Short-chain dehydrogenase reductase Sdr
IAU62_RS10450	COG3976	FMN-binding domain protein
IAU62_RS10450	COG0431	NADPH-dependent FMN reductase
IAU62_RS10450	COG1053	succinate dehydrogenase
IAU62_RS10460	COG0803	Belongs to the bacterial solute-binding protein 9 family
IAU62_RS10475	COG0523	cobalamin synthesis protein
IAU62_RS10500	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IAU62_RS10505	COG0156	8-amino-7-oxononanoate synthase activity
IAU62_RS10510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAU62_RS10515	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IAU62_RS10530	COG1131	(ABC) transporter
IAU62_RS10545	COG0438	transferase activity, transferring glycosyl groups
IAU62_RS10550	COG0653	protein targeting
IAU62_RS10560	COG1073	alpha beta
IAU62_RS10570	COG0201	protein transport
IAU62_RS10575	COG3391	amine dehydrogenase activity
IAU62_RS10615	COG1755	Isoprenylcysteine carboxyl methyltransferase
IAU62_RS10625	COG0579	oxidoreductase
IAU62_RS10630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAU62_RS10665	COG0668	transmembrane transport
IAU62_RS10690	COG0640	Transcriptional regulator
IAU62_RS10710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAU62_RS10715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAU62_RS10720	COG0730	response to heat
IAU62_RS10725	COG1937	Protein conserved in bacteria
IAU62_RS10730	COG2210	Belongs to the sulfur carrier protein TusA family
IAU62_RS10735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IAU62_RS10740	COG1388	LysM domain
IAU62_RS10745	COG2132	Multicopper oxidase
IAU62_RS10750	COG2217	Heavy metal translocating P-type atpase
IAU62_RS10760	COG0477	Major facilitator Superfamily
IAU62_RS10790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IAU62_RS10790	COG1199	ATP-dependent helicase activity
IAU62_RS10825	COG2030	dehydratase
IAU62_RS10830	COG0584	glycerophosphoryl diester phosphodiesterase
IAU62_RS10875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IAU62_RS10920	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IAU62_RS10925	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IAU62_RS10930	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IAU62_RS10940	COG4863	YycH protein
IAU62_RS10945	COG5002	protein histidine kinase activity
IAU62_RS10950	COG0745	RESPONSE REGULATOR receiver
IAU62_RS10965	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAU62_RS10970	COG0305	Participates in initiation and elongation during chromosome replication
IAU62_RS10975	COG0359	binds to the 23S rRNA
IAU62_RS10980	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
IAU62_RS10990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAU62_RS11010	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IAU62_RS11015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IAU62_RS11020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IAU62_RS11025	COG0187	DNA topoisomerase II activity
IAU62_RS11030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IAU62_RS11035	COG2501	S4 domain
IAU62_RS11040	COG0592	DNA-directed DNA polymerase activity
IAU62_RS11045	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAU62_RS11055	COG0594	ribonuclease P activity
IAU62_RS11060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IAU62_RS11065	COG0445	tRNA wobble uridine modification
IAU62_RS11070	COG0357	Ribosomal RNA small subunit methyltransferase G
IAU62_RS11075	COG1475	DNA binding
IAU62_RS11110	COG1136	(ABC) transporter
IAU62_RS11115	COG0577	efflux transmembrane transporter activity
IAU62_RS11130	COG0577	efflux transmembrane transporter activity
IAU62_RS11135	COG1136	(ABC) transporter
IAU62_RS11160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAU62_RS11180	COG4555	ABC transporter
IAU62_RS11190	COG1476	TRANSCRIPTIONal
IAU62_RS11205	COG0183	Belongs to the thiolase family
IAU62_RS11215	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IAU62_RS11220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IAU62_RS11220	COG0646	methionine synthase
IAU62_RS11225	COG0626	cystathionine gamma-synthase activity
IAU62_RS11230	COG0626	cystathionine gamma-synthase activity
IAU62_RS11235	COG1475	DNA binding
IAU62_RS11240	COG0668	transmembrane transport
IAU62_RS11245	COG4481	Protein conserved in bacteria
IAU62_RS11250	COG0012	GTP binding
IAU62_RS11265	COG0360	Binds together with S18 to 16S ribosomal RNA
IAU62_RS11275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IAU62_RS11280	COG0693	protein deglycase activity
IAU62_RS11290	COG1846	Transcriptional regulator
IAU62_RS11315	COG1280	lysine exporter protein (LysE YggA)
IAU62_RS11320	COG0406	alpha-ribazole phosphatase activity
IAU62_RS11335	COG3634	alkyl hydroperoxide reductase activity
IAU62_RS11340	COG0450	alkyl hydroperoxide reductase
IAU62_RS11350	COG0778	Nitroreductase
IAU62_RS11355	COG1823	symporter activity
IAU62_RS11360	COG5183	chlorophyll binding
IAU62_RS11375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAU62_RS11380	COG2233	PERMEase
IAU62_RS11385	COG0517	IMP dehydrogenase activity
IAU62_RS11385	COG0516	GMP reductase activity
IAU62_RS11390	COG0519	Catalyzes the synthesis of GMP from XMP
IAU62_RS11390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAU62_RS11430	COG0523	cobalamin synthesis protein
IAU62_RS11450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAU62_RS11455	COG3002	Belongs to the UPF0753 family
IAU62_RS11460	COG5609	conserved protein (DUF2294)
IAU62_RS11475	COG1647	Serine aminopeptidase, S33
IAU62_RS11485	COG0733	neurotransmitter:sodium symporter activity
IAU62_RS11495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAU62_RS11500	COG0626	cystathionine gamma-synthase activity
IAU62_RS11505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAU62_RS11510	COG2011	ABC-type metal ion transport system permease component
IAU62_RS11520	COG1388	LysM domain
IAU62_RS11520	COG3942	CHAP domain
IAU62_RS11525	COG0438	transferase activity, transferring glycosyl groups
IAU62_RS11550	COG0583	DNA-binding transcription factor activity
IAU62_RS11555	COG0070	glutamate synthase
IAU62_RS11555	COG0067	glutamate synthase
IAU62_RS11555	COG0069	glutamate synthase activity
IAU62_RS11560	COG0493	'glutamate synthase
IAU62_RS11580	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAU62_RS11585	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IAU62_RS11590	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IAU62_RS11615	COG1982	Orn Lys Arg decarboxylase major
IAU62_RS11620	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAU62_RS11625	COG3870	Protein conserved in bacteria
IAU62_RS11630	COG0470	DNA polymerase III
IAU62_RS11635	COG1774	PSP1 C-terminal conserved region
IAU62_RS11640	COG4467	Involved in initiation control of chromosome replication
IAU62_RS11645	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IAU62_RS11650	COG2827	Endonuclease containing a URI domain
IAU62_RS11655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IAU62_RS11660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAU62_RS11660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAU62_RS11665	COG0084	hydrolase, TatD family'
IAU62_RS11670	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IAU62_RS11675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IAU62_RS11680	COG4466	Protein conserved in bacteria
IAU62_RS11685	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IAU62_RS11690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAU62_RS11695	COG0251	oxidation-reduction process
IAU62_RS11700	COG2088	sporulation resulting in formation of a cellular spore
IAU62_RS11705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IAU62_RS11710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IAU62_RS11715	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IAU62_RS11720	COG0193	aminoacyl-tRNA hydrolase activity
IAU62_RS11725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAU62_RS11730	COG2244	polysaccharide biosynthetic process
IAU62_RS11735	COG3956	TIGRFAM MazG family protein
IAU62_RS11740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IAU62_RS11750	COG1098	S1 RNA binding domain
IAU62_RS11755	COG0037	tRNA processing
IAU62_RS11760	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IAU62_RS11765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAU62_RS11770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IAU62_RS11775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IAU62_RS11780	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IAU62_RS11785	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IAU62_RS11790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IAU62_RS11795	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IAU62_RS11880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAU62_RS11885	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IAU62_RS11890	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IAU62_RS11895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IAU62_RS11900	COG4463	regulation of RNA biosynthetic process
IAU62_RS11905	COG3880	PFAM UvrB UvrC protein
IAU62_RS11910	COG3869	Catalyzes the specific phosphorylation of arginine residues in
IAU62_RS11915	COG0542	response to heat
IAU62_RS11920	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IAU62_RS11925	COG4956	integral membrane protein (PIN domain superfamily)
IAU62_RS11930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAU62_RS11935	COG1045	serine acetyltransferase
IAU62_RS11940	COG0215	cysteine-tRNA ligase activity
IAU62_RS11945	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IAU62_RS11950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAU62_RS11955	COG3688	RNA-binding protein containing a PIN domain
IAU62_RS11965	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IAU62_RS11970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAU62_RS11975	COG0250	Participates in transcription elongation, termination and antitermination
IAU62_RS11980	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IAU62_RS11985	COG0081	regulation of translation
IAU62_RS11990	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IAU62_RS11995	COG0222	ribosome binding
IAU62_RS12000	COG2813	Specifically methylates the guanine in position
IAU62_RS12005	COG0085	RNA polymerase activity
IAU62_RS12010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAU62_RS12020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IAU62_RS12030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAU62_RS12035	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IAU62_RS12040	COG1473	amidohydrolase
IAU62_RS12060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity