locus-tag	class	description
C7J90_RS00015	COG3091	SprT-like family
C7J90_RS00020	COG2183	response to ionizing radiation
C7J90_RS00025	COG1191	sigma factor activity
C7J90_RS00035	COG1366	Belongs to the anti-sigma-factor antagonist family
C7J90_RS00040	COG2208	phosphoserine phosphatase activity
C7J90_RS00045	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7J90_RS00060	COG0736	holo-[acyl-carrier-protein] synthase activity
C7J90_RS00080	COG0513	Belongs to the DEAD box helicase family
C7J90_RS00085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7J90_RS00090	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7J90_RS00095	COG0772	Belongs to the SEDS family
C7J90_RS00100	COG2217	Heavy metal translocating P-type atpase
C7J90_RS00105	COG2608	mercury ion transmembrane transporter activity
C7J90_RS00115	COG1937	Protein conserved in bacteria
C7J90_RS00125	COG1418	mRNA catabolic process
C7J90_RS00130	COG0706	membrane insertase activity
C7J90_RS00135	COG0352	thiamine-phosphate diphosphorylase activity
C7J90_RS00140	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7J90_RS00150	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7J90_RS00175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7J90_RS00180	COG4836	Membrane
C7J90_RS00185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7J90_RS00190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7J90_RS00195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7J90_RS00205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7J90_RS00210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7J90_RS00215	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7J90_RS00220	COG0356	it plays a direct role in the translocation of protons across the membrane
C7J90_RS00230	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7J90_RS00235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7J90_RS00240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7J90_RS00245	COG4475	Protein of unknown function (DUF436)
C7J90_RS00250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7J90_RS00255	COG0009	L-threonylcarbamoyladenylate synthase
C7J90_RS00260	COG2890	protein-(glutamine-N5) methyltransferase activity
C7J90_RS00265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7J90_RS00270	COG1435	thymidine kinase activity
C7J90_RS00275	COG0254	rRNA binding
C7J90_RS00280	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7J90_RS00285	COG1012	belongs to the aldehyde dehydrogenase family
C7J90_RS00290	COG1733	regulation of RNA biosynthetic process
C7J90_RS00295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7J90_RS00300	COG0191	fructose-bisphosphate aldolase activity
C7J90_RS00305	COG4821	SIS domain
C7J90_RS00320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7J90_RS00330	COG5146	pantothenate kinase activity
C7J90_RS00360	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7J90_RS00375	COG1757	Na H antiporter
C7J90_RS00390	COG1482	cell wall glycoprotein biosynthetic process
C7J90_RS00395	COG2186	Transcriptional regulator
C7J90_RS00410	COG1119	ATPase activity
C7J90_RS00415	COG3344	reverse transcriptase
C7J90_RS00430	COG3711	transcriptional antiterminator
C7J90_RS00440	COG0246	Mannitol dehydrogenase
C7J90_RS00450	COG2801	Transposase and inactivated derivatives
C7J90_RS00455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7J90_RS00515	COG0489	protein tyrosine kinase activity
C7J90_RS00520	COG2814	Major facilitator Superfamily
C7J90_RS00535	COG1272	protein, Hemolysin III
C7J90_RS00540	COG4284	Utp--glucose-1-phosphate uridylyltransferase
C7J90_RS00545	COG1988	membrane-bound metal-dependent
C7J90_RS00555	COG3314	Sporulation integral membrane protein YlbJ
C7J90_RS00560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J90_RS00565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J90_RS00570	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7J90_RS00575	COG3457	Alanine racemase
C7J90_RS00580	COG4264	IucA IucC family
C7J90_RS00585	COG2814	Major facilitator Superfamily
C7J90_RS00595	COG2814	Major facilitator Superfamily
C7J90_RS00615	COG1302	Protein conserved in bacteria
C7J90_RS00630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7J90_RS00650	COG1518	maintenance of DNA repeat elements
C7J90_RS00665	COG0346	lactoylglutathione lyase activity
C7J90_RS00710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7J90_RS00715	COG0557	exoribonuclease II activity
C7J90_RS00720	COG1647	Serine aminopeptidase, S33
C7J90_RS00725	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7J90_RS00735	COG0148	phosphopyruvate hydratase activity
C7J90_RS00740	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7J90_RS00745	COG0149	triose-phosphate isomerase activity
C7J90_RS00750	COG0126	phosphoglycerate kinase activity
C7J90_RS00800	COG3844	kynureninase activity
C7J90_RS00805	COG1278	Cold shock
C7J90_RS00815	COG0740	serine-type endopeptidase activity
C7J90_RS00825	COG2801	Transposase and inactivated derivatives
C7J90_RS00840	COG1302	Protein conserved in bacteria
C7J90_RS00855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7J90_RS00885	COG1518	maintenance of DNA repeat elements
C7J90_RS00895	COG1481	regulation of sporulation
C7J90_RS00900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7J90_RS00905	COG1660	Displays ATPase and GTPase activities
C7J90_RS00910	COG0492	ferredoxin-NADP+ reductase activity
C7J90_RS00920	COG0110	maltose O-acetyltransferase activity
C7J90_RS00925	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7J90_RS00930	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7J90_RS00970	COG0653	protein targeting
C7J90_RS00975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7J90_RS00980	COG1040	competence protein
C7J90_RS00985	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7J90_RS00995	COG1739	Uncharacterized protein family UPF0029
C7J90_RS01000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7J90_RS01020	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7J90_RS01030	COG3118	belongs to the thioredoxin family
C7J90_RS01045	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7J90_RS01055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7J90_RS01060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7J90_RS01075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7J90_RS01080	COG3104	oligopeptide transport
C7J90_RS01085	COG3104	oligopeptide transport
C7J90_RS01100	COG2197	response regulator
C7J90_RS01105	COG2203	Gaf domain
C7J90_RS01105	COG4585	Histidine kinase
C7J90_RS01110	COG0842	Transport permease protein
C7J90_RS01115	COG1131	(ABC) transporter
C7J90_RS01125	COG1174	glycine betaine transport
C7J90_RS01135	COG0514	ATP-dependent DNA helicase (RecQ)
C7J90_RS01140	COG0488	(ABC) transporter
C7J90_RS01150	COG1368	sulfuric ester hydrolase activity
C7J90_RS01180	COG0512	Glutamine amidotransferase of anthranilate synthase
C7J90_RS01185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7J90_RS01190	COG0720	synthase
C7J90_RS01210	COG0463	Glycosyl transferase, family 2
C7J90_RS01215	COG1253	flavin adenine dinucleotide binding
C7J90_RS01220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7J90_RS01220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7J90_RS01220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7J90_RS01225	COG1105	Belongs to the carbohydrate kinase PfkB family
C7J90_RS01230	COG1349	DNA-binding transcription factor activity
C7J90_RS01235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7J90_RS01240	COG0463	Glycosyl transferase, family 2
C7J90_RS01240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7J90_RS01265	COG0039	L-malate dehydrogenase activity
C7J90_RS01275	COG4989	oxidoreductase activity
C7J90_RS01280	COG0523	cobalamin synthesis protein
C7J90_RS01290	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7J90_RS01295	COG4988	ABC transporter
C7J90_RS01300	COG1968	undecaprenyl-diphosphatase activity
C7J90_RS01310	COG1671	Belongs to the UPF0178 family
C7J90_RS01315	COG1611	Belongs to the LOG family
C7J90_RS01345	COG2839	Protein conserved in bacteria
C7J90_RS01350	COG2814	Major facilitator Superfamily
C7J90_RS01355	COG0583	DNA-binding transcription factor activity
C7J90_RS01365	COG0217	transcriptional regulatory protein
C7J90_RS01375	COG2022	thiamine diphosphate biosynthetic process
C7J90_RS01395	COG1388	LysM domain
C7J90_RS01395	COG3942	CHAP domain
C7J90_RS01405	COG0306	phosphate transporter
C7J90_RS01410	COG1392	Phosphate transport regulator
C7J90_RS01415	COG0577	efflux transmembrane transporter activity
C7J90_RS01420	COG1136	(ABC) transporter
C7J90_RS01430	COG0745	RESPONSE REGULATOR receiver
C7J90_RS01435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7J90_RS01445	COG0657	acetylesterase activity
C7J90_RS01455	COG0477	Major facilitator Superfamily
C7J90_RS01460	COG3344	reverse transcriptase
C7J90_RS01470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J90_RS01475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J90_RS01480	COG1120	ATPase activity
C7J90_RS01485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7J90_RS01490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7J90_RS01510	COG1132	(ABC) transporter
C7J90_RS01520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7J90_RS01525	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7J90_RS01530	COG1682	transport, permease protein
C7J90_RS01535	COG1134	teichoic acid transport
C7J90_RS01555	COG1121	(ABC) transporter
C7J90_RS01560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7J90_RS01565	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7J90_RS01570	COG1320	monovalent cation:proton antiporter activity
C7J90_RS01575	COG2212	antiporter activity
C7J90_RS01580	COG1863	multisubunit Na H antiporter MnhE subunit
C7J90_RS01590	COG1006	Multisubunit Na H antiporter MnhC subunit
C7J90_RS01595	COG2111	Na H antiporter
C7J90_RS01600	COG2111	Na H antiporter
C7J90_RS01600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7J90_RS01605	COG0582	viral genome integration into host DNA
C7J90_RS01645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7J90_RS01650	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
C7J90_RS01655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J90_RS01660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7J90_RS01670	COG0018	arginyl-trna synthetase
C7J90_RS01690	COG1078	dGTPase activity
C7J90_RS01700	COG4844	belongs to the
C7J90_RS01705	COG0471	metal ion transport
C7J90_RS01720	COG0531	amino acid
C7J90_RS01730	COG0280	phosphate acetyltransferase
C7J90_RS01735	COG0095	Lipoate-protein ligase
C7J90_RS01745	COG2814	Major facilitator Superfamily
C7J90_RS01750	COG1566	PFAM secretion protein HlyD family protein
C7J90_RS01770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7J90_RS01775	COG0531	amino acid
C7J90_RS01780	COG2363	Small membrane protein
C7J90_RS01790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7J90_RS01805	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7J90_RS01810	COG0363	glucosamine-6-phosphate deaminase activity
C7J90_RS01815	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
C7J90_RS01820	COG0517	IMP dehydrogenase activity
C7J90_RS01820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7J90_RS01830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7J90_RS01840	COG0431	NADPH-dependent FMN reductase
C7J90_RS01845	COG0561	phosphatase activity
C7J90_RS01855	COG1428	Deoxynucleoside kinase
C7J90_RS01860	COG1428	Deoxynucleoside kinase
C7J90_RS01865	COG0546	phosphoglycolate phosphatase activity
C7J90_RS01880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7J90_RS01890	COG1473	amidohydrolase
C7J90_RS01895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7J90_RS01900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7J90_RS01905	COG0049	tRNA binding
C7J90_RS01910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7J90_RS01920	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7J90_RS01930	COG2813	Specifically methylates the guanine in position
C7J90_RS01940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7J90_RS01945	COG0081	regulation of translation
C7J90_RS01950	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7J90_RS01955	COG0250	Participates in transcription elongation, termination and antitermination
C7J90_RS01960	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7J90_RS01965	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7J90_RS01975	COG3688	RNA-binding protein containing a PIN domain
C7J90_RS01985	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7J90_RS01990	COG0215	cysteine-tRNA ligase activity
C7J90_RS01995	COG1045	serine acetyltransferase
C7J90_RS02005	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7J90_RS02015	COG4956	integral membrane protein (PIN domain superfamily)
C7J90_RS02020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7J90_RS02030	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C7J90_RS02035	COG3880	PFAM UvrB UvrC protein
C7J90_RS02045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7J90_RS02050	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C7J90_RS02055	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C7J90_RS02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7J90_RS02150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7J90_RS02155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7J90_RS02160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7J90_RS02170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7J90_RS02180	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7J90_RS02185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7J90_RS02200	COG1098	S1 RNA binding domain
C7J90_RS02210	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7J90_RS02215	COG3956	TIGRFAM MazG family protein
C7J90_RS02220	COG2244	polysaccharide biosynthetic process
C7J90_RS02225	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7J90_RS02230	COG0193	aminoacyl-tRNA hydrolase activity
C7J90_RS02240	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7J90_RS02245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7J90_RS02250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7J90_RS02255	COG2088	sporulation resulting in formation of a cellular spore
C7J90_RS02260	COG0251	oxidation-reduction process
C7J90_RS02265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7J90_RS02270	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7J90_RS02275	COG4466	Protein conserved in bacteria
C7J90_RS02280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7J90_RS02285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7J90_RS02290	COG0084	hydrolase, TatD family'
C7J90_RS02295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7J90_RS02295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7J90_RS02300	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7J90_RS02305	COG2827	Endonuclease containing a URI domain
C7J90_RS02310	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7J90_RS02315	COG4467	Involved in initiation control of chromosome replication
C7J90_RS02320	COG1774	PSP1 C-terminal conserved region
C7J90_RS02325	COG0470	DNA polymerase III
C7J90_RS02330	COG3870	Protein conserved in bacteria
C7J90_RS02335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7J90_RS02340	COG1982	Orn Lys Arg decarboxylase major
C7J90_RS02365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7J90_RS02370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7J90_RS02375	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7J90_RS02390	COG2188	Transcriptional regulator
C7J90_RS02395	COG0366	Alpha amylase catalytic
C7J90_RS02400	COG1263	PTS System
C7J90_RS02400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7J90_RS02405	COG2814	Major facilitator Superfamily
C7J90_RS02415	COG0493	'glutamate synthase
C7J90_RS02420	COG0070	glutamate synthase
C7J90_RS02420	COG0067	glutamate synthase
C7J90_RS02420	COG0069	glutamate synthase activity
C7J90_RS02425	COG0583	DNA-binding transcription factor activity
C7J90_RS02440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7J90_RS02460	COG0626	cystathionine gamma-synthase activity
C7J90_RS02465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7J90_RS02470	COG2272	Belongs to the type-B carboxylesterase lipase family
C7J90_RS02475	COG0733	neurotransmitter:sodium symporter activity
C7J90_RS02495	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7J90_RS02500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7J90_RS02500	COG0574	Belongs to the PEP-utilizing enzyme family
C7J90_RS02510	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7J90_RS02535	COG0531	amino acid
C7J90_RS02550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7J90_RS02550	COG0456	acetyltransferase
C7J90_RS02560	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7J90_RS02585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7J90_RS02585	COG0519	Catalyzes the synthesis of GMP from XMP
C7J90_RS02590	COG0516	GMP reductase activity
C7J90_RS02590	COG0517	IMP dehydrogenase activity
C7J90_RS02595	COG2233	PERMEase
C7J90_RS02600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7J90_RS02615	COG5183	chlorophyll binding
C7J90_RS02620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7J90_RS02625	COG1823	symporter activity
C7J90_RS02630	COG0778	Nitroreductase
C7J90_RS02650	COG0450	alkyl hydroperoxide reductase
C7J90_RS02655	COG3634	alkyl hydroperoxide reductase activity
C7J90_RS02665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7J90_RS02685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7J90_RS02690	COG2011	ABC-type metal ion transport system permease component
C7J90_RS02695	COG1464	Belongs to the NlpA lipoprotein family
C7J90_RS02700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7J90_RS02710	COG0360	Binds together with S18 to 16S ribosomal RNA
C7J90_RS02720	COG2910	NAD(P)H-binding
C7J90_RS02725	COG3344	reverse transcriptase
C7J90_RS02760	COG0494	nUDIX hydrolase
C7J90_RS02765	COG2814	Major facilitator Superfamily
C7J90_RS02775	COG0012	GTP binding
C7J90_RS02780	COG4481	Protein conserved in bacteria
C7J90_RS02785	COG0668	transmembrane transport
C7J90_RS02790	COG1475	DNA binding
C7J90_RS02795	COG0626	cystathionine gamma-synthase activity
C7J90_RS02800	COG0626	cystathionine gamma-synthase activity
C7J90_RS02805	COG0646	methionine synthase
C7J90_RS02805	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7J90_RS02825	COG0829	nickel cation binding
C7J90_RS02830	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C7J90_RS02835	COG0830	nickel cation binding
C7J90_RS02840	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
C7J90_RS02850	COG0804	urea catabolic process
C7J90_RS02855	COG1966	Carbon starvation protein
C7J90_RS02890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7J90_RS02905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7J90_RS02915	COG3716	PTS system mannose fructose sorbose family IID component
C7J90_RS02920	COG3715	PTS system
C7J90_RS02925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7J90_RS02940	COG1105	Belongs to the carbohydrate kinase PfkB family
C7J90_RS02945	COG2222	sugar isomerase
C7J90_RS02955	COG0366	Alpha amylase catalytic
C7J90_RS02965	COG0357	Ribosomal RNA small subunit methyltransferase G
C7J90_RS02970	COG0445	tRNA wobble uridine modification
C7J90_RS02975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7J90_RS02980	COG0594	ribonuclease P activity
C7J90_RS02990	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7J90_RS02995	COG0592	DNA-directed DNA polymerase activity
C7J90_RS03000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7J90_RS03010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7J90_RS03015	COG0187	DNA topoisomerase II activity
C7J90_RS03025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7J90_RS03030	COG2986	histidine ammonia-lyase
C7J90_RS03040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7J90_RS03050	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7J90_RS03055	COG0359	binds to the 23S rRNA
C7J90_RS03060	COG0305	Participates in initiation and elongation during chromosome replication
C7J90_RS03065	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7J90_RS03075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7J90_RS03090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7J90_RS03095	COG0157	Belongs to the NadC ModD family
C7J90_RS03100	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7J90_RS03105	COG1104	cysteine desulfurase activity
C7J90_RS03120	COG0745	RESPONSE REGULATOR receiver
C7J90_RS03125	COG5002	protein histidine kinase activity
C7J90_RS03130	COG4863	YycH protein
C7J90_RS03140	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7J90_RS03190	COG2207	Transcriptional regulator
C7J90_RS03195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7J90_RS03200	COG0492	ferredoxin-NADP+ reductase activity
C7J90_RS03245	COG0577	efflux transmembrane transporter activity
C7J90_RS03250	COG1136	(ABC) transporter
C7J90_RS03255	COG2205	protein histidine kinase activity
C7J90_RS03260	COG0745	RESPONSE REGULATOR receiver
C7J90_RS03270	COG1131	(ABC) transporter
C7J90_RS03280	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7J90_RS03310	COG3477	response to acidic pH
C7J90_RS03320	COG0415	Belongs to the DNA photolyase family
C7J90_RS03325	COG0492	ferredoxin-NADP+ reductase activity
C7J90_RS03335	COG0745	RESPONSE REGULATOR receiver
C7J90_RS03340	COG0642	Histidine kinase
C7J90_RS03345	COG3842	ATPase activity
C7J90_RS03350	COG4209	transmembrane transport
C7J90_RS03360	COG0395	ABC-type sugar transport system, permease component
C7J90_RS03370	COG0534	Mate efflux family protein
C7J90_RS03375	COG1349	DNA-binding transcription factor activity
C7J90_RS03380	COG0702	epimerase
C7J90_RS03395	COG0586	Pfam SNARE associated Golgi protein
C7J90_RS03400	COG1609	Transcriptional regulator
C7J90_RS03410	COG1869	D-ribose catabolic process
C7J90_RS03420	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7J90_RS03430	COG1028	Short-chain dehydrogenase reductase Sdr
C7J90_RS03455	COG1454	alcohol dehydrogenase
C7J90_RS03455	COG1012	belongs to the aldehyde dehydrogenase family
C7J90_RS03460	COG2188	Transcriptional regulator
C7J90_RS03465	COG0813	purine-nucleoside phosphorylase activity
C7J90_RS03470	COG2814	Major facilitator Superfamily
C7J90_RS03475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7J90_RS03485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7J90_RS03485	COG3711	transcriptional antiterminator
C7J90_RS03490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7J90_RS03490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7J90_RS03490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7J90_RS03495	COG1482	cell wall glycoprotein biosynthetic process
C7J90_RS03515	COG1876	peptidase activity
C7J90_RS03535	COG0156	8-amino-7-oxononanoate synthase activity
C7J90_RS03540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7J90_RS03545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C7J90_RS03550	COG0737	Belongs to the 5'-nucleotidase family
C7J90_RS03585	COG1279	arginine transmembrane transporter activity
C7J90_RS03590	COG1278	Cold shock
C7J90_RS03595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7J90_RS03605	COG3314	Sporulation integral membrane protein YlbJ
C7J90_RS03630	COG0475	glutathione-regulated potassium exporter activity
C7J90_RS03635	COG0490	domain, Protein
C7J90_RS03650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7J90_RS03655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7J90_RS03660	COG2210	Belongs to the sulfur carrier protein TusA family
C7J90_RS03670	COG1335	isochorismatase
C7J90_RS03700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7J90_RS03705	COG0745	RESPONSE REGULATOR receiver
C7J90_RS03710	COG2205	protein histidine kinase activity
C7J90_RS03720	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C7J90_RS03725	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C7J90_RS03755	COG2235	arginine
C7J90_RS03760	COG1438	arginine binding
C7J90_RS03780	COG0747	negative chemotaxis
C7J90_RS03785	COG0601	transmembrane transport
C7J90_RS03795	COG0444	Belongs to the ABC transporter superfamily
C7J90_RS03800	COG1124	(ABC) transporter
C7J90_RS03810	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7J90_RS03815	COG2318	DinB family
C7J90_RS03825	COG2814	Major facilitator Superfamily
C7J90_RS03830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7J90_RS03850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7J90_RS03875	COG2801	Transposase and inactivated derivatives
C7J90_RS03885	COG0400	carboxylic ester hydrolase activity
C7J90_RS03890	COG0346	lactoylglutathione lyase activity
C7J90_RS03895	COG1846	Transcriptional regulator
C7J90_RS03900	COG2388	GCN5-related N-acetyl-transferase
C7J90_RS03910	COG2353	YceI-like domain
C7J90_RS03915	COG0783	Belongs to the Dps family
C7J90_RS03935	COG1136	(ABC) transporter
C7J90_RS03945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7J90_RS03975	COG0579	oxidoreductase
C7J90_RS03985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7J90_RS04005	COG0730	response to heat
C7J90_RS04010	COG1937	Protein conserved in bacteria
C7J90_RS04015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7J90_RS04015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7J90_RS04045	COG1328	CTP reductase activity
C7J90_RS04050	COG0602	queuosine metabolic process
C7J90_RS04075	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7J90_RS04085	COG3588	fructose-bisphosphate aldolase
C7J90_RS04105	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C7J90_RS04135	COG1115	amino acid carrier protein
C7J90_RS04140	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C7J90_RS04150	COG0588	phosphoglycerate mutase activity
C7J90_RS04165	COG1957	nucleoside hydrolase
C7J90_RS04180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7J90_RS04185	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7J90_RS04210	COG1785	Belongs to the alkaline phosphatase family
C7J90_RS04220	COG3527	Alpha-acetolactate decarboxylase
C7J90_RS04230	COG2258	MOSC domain
C7J90_RS04235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7J90_RS04240	COG1510	regulation of RNA biosynthetic process
C7J90_RS04245	COG1012	belongs to the aldehyde dehydrogenase family
C7J90_RS04250	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
C7J90_RS04265	COG0535	radical SAM domain protein
C7J90_RS04270	COG1131	(ABC) transporter
C7J90_RS04305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7J90_RS04315	COG0107	imidazoleglycerol-phosphate synthase activity
C7J90_RS04320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7J90_RS04340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7J90_RS04345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7J90_RS04355	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7J90_RS04385	COG2376	Dihydroxyacetone kinase
C7J90_RS04390	COG1461	Dihydroxyacetone kinase
C7J90_RS04400	COG2824	Alkylphosphonate utilization operon protein PhnA
C7J90_RS04405	COG1012	belongs to the aldehyde dehydrogenase family
C7J90_RS04410	COG2832	Protein of unknown function (DUF454)
C7J90_RS04425	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7J90_RS04425	COG3942	CHAP domain
C7J90_RS04445	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7J90_RS04450	COG0747	negative chemotaxis
C7J90_RS04475	COG0463	Glycosyl transferase, family 2
C7J90_RS04475	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7J90_RS04480	COG0463	Glycosyl transferase, family 2
C7J90_RS04480	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7J90_RS04485	COG0438	transferase activity, transferring glycosyl groups
C7J90_RS04490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7J90_RS04505	COG3181	Tripartite tricarboxylate transporter family receptor
C7J90_RS04510	COG0778	Nitroreductase
C7J90_RS04515	COG3001	Fructosamine kinase
C7J90_RS04535	COG1136	(ABC) transporter
C7J90_RS04540	COG0577	efflux transmembrane transporter activity
C7J90_RS04545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7J90_RS04555	COG4413	Urea transporter
C7J90_RS04565	COG0832	Belongs to the urease beta subunit family
C7J90_RS04570	COG0804	urea catabolic process
C7J90_RS04575	COG0717	Belongs to the dCTP deaminase family
C7J90_RS04585	COG2348	transferase activity, transferring amino-acyl groups
C7J90_RS04595	COG0583	DNA-binding transcription factor activity
C7J90_RS04610	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7J90_RS04615	COG4605	iron ion homeostasis
C7J90_RS04620	COG4604	ABC transporter, ATP-binding protein
C7J90_RS04625	COG4607	ABC-type enterochelin transport system periplasmic component
C7J90_RS04630	COG1846	Transcriptional regulator
C7J90_RS04635	COG0778	Nitroreductase
C7J90_RS04640	COG2357	RelA SpoT domain protein
C7J90_RS04650	COG1136	(ABC) transporter
C7J90_RS04690	COG3583	domain protein
C7J90_RS04690	COG4932	domain protein
C7J90_RS04690	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7J90_RS04695	COG1028	Short-chain dehydrogenase reductase Sdr
C7J90_RS04700	COG0753	catalase activity
C7J90_RS04710	COG1028	Short-chain dehydrogenase reductase Sdr
C7J90_RS04735	COG2816	NAD+ diphosphatase activity
C7J90_RS04745	COG3835	regulator
C7J90_RS04755	COG3344	reverse transcriptase
C7J90_RS04765	COG4336	lyase activity
C7J90_RS04770	COG3961	Belongs to the TPP enzyme family
C7J90_RS04775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7J90_RS04780	COG0512	Glutamine amidotransferase of anthranilate synthase
C7J90_RS04785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7J90_RS04790	COG0134	indole-3-glycerol-phosphate synthase activity
C7J90_RS04795	COG0133	tryptophan synthase activity
C7J90_RS04800	COG0159	tryptophan synthase activity
C7J90_RS04805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C7J90_RS04815	COG1132	(ABC) transporter
C7J90_RS04820	COG1132	(ABC) transporter
C7J90_RS04850	COG1129	ABC transporter
C7J90_RS04855	COG1132	(ABC) transporter
C7J90_RS04855	COG2375	cellular response to nickel ion
C7J90_RS04860	COG1132	(ABC) transporter
C7J90_RS04870	COG1115	amino acid carrier protein
C7J90_RS04885	COG2271	Major facilitator Superfamily
C7J90_RS04890	COG3764	Sortase (surface protein transpeptidase)
C7J90_RS04895	COG1929	Belongs to the glycerate kinase type-1 family
C7J90_RS04920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7J90_RS04930	COG0702	epimerase
C7J90_RS04935	COG4166	transmembrane transport
C7J90_RS04940	COG0444	Belongs to the ABC transporter superfamily
C7J90_RS04945	COG4608	Belongs to the ABC transporter superfamily
C7J90_RS04950	COG0601	transmembrane transport
C7J90_RS04955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7J90_RS04970	COG0018	arginyl-trna synthetase
C7J90_RS04975	COG1760	l-serine dehydratase
C7J90_RS04980	COG1760	l-serine dehydratase
C7J90_RS05005	COG0471	metal ion transport
C7J90_RS05020	COG0454	-acetyltransferase
C7J90_RS05025	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7J90_RS05030	COG1648	precorrin-2 dehydrogenase activity
C7J90_RS05030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7J90_RS05035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7J90_RS05040	COG2146	nitrite reductase [NAD(P)H] activity
C7J90_RS05050	COG0737	Belongs to the 5'-nucleotidase family
C7J90_RS05055	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7J90_RS05060	COG1140	nitrate reductase beta subunit
C7J90_RS05065	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7J90_RS05070	COG2181	nitrate reductase activity
C7J90_RS05080	COG4585	Histidine kinase
C7J90_RS05085	COG2197	response regulator
C7J90_RS05090	COG2223	nitrite transmembrane transporter activity
C7J90_RS05095	COG4187	Peptidase family M20/M25/M40
C7J90_RS05105	COG1363	Peptidase, m42
C7J90_RS05110	COG0697	spore germination
C7J90_RS05120	COG2807	transmembrane transport
C7J90_RS05125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7J90_RS05145	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7J90_RS05170	COG0456	acetyltransferase
C7J90_RS05175	COG2814	Major facilitator Superfamily
C7J90_RS05180	COG0604	alcohol dehydrogenase
C7J90_RS05190	COG1620	l-lactate permease
C7J90_RS05195	COG0438	transferase activity, transferring glycosyl groups
C7J90_RS05200	COG0579	oxidoreductase
C7J90_RS05205	COG2814	Major facilitator Superfamily
C7J90_RS05210	COG1234	tRNA 3'-trailer cleavage
C7J90_RS05240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7J90_RS05245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7J90_RS05255	COG0745	RESPONSE REGULATOR receiver
C7J90_RS05260	COG0577	efflux transmembrane transporter activity
C7J90_RS05280	COG4640	response to antibiotic
C7J90_RS05290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7J90_RS05300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7J90_RS05305	COG0657	acetylesterase activity
C7J90_RS05325	COG0523	cobalamin synthesis protein
C7J90_RS05330	COG0786	glutamate:sodium symporter activity
C7J90_RS05335	COG2207	Transcriptional regulator
C7J90_RS05385	COG1757	Na H antiporter
C7J90_RS05390	COG2094	Belongs to the DNA glycosylase MPG family
C7J90_RS05395	COG3152	Membrane
C7J90_RS05410	COG3344	reverse transcriptase
C7J90_RS05415	COG1288	antiporter activity
C7J90_RS05420	COG4152	abc transporter atp-binding protein
C7J90_RS05425	COG1668	transmembrane transport
C7J90_RS05430	COG1742	UPF0060 membrane protein
C7J90_RS05435	COG2017	converts alpha-aldose to the beta-anomer
C7J90_RS05440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7J90_RS05445	COG1266	CAAX protease self-immunity
C7J90_RS05455	COG0583	DNA-binding transcription factor activity
C7J90_RS05460	COG3314	Sporulation integral membrane protein YlbJ
C7J90_RS05465	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C7J90_RS05470	COG1228	amidohydrolase
C7J90_RS05475	COG1473	amidohydrolase
C7J90_RS05495	COG0385	Bile acid
C7J90_RS05505	COG0346	lactoylglutathione lyase activity
C7J90_RS05510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7J90_RS05535	COG1113	amino acid transport
C7J90_RS05575	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7J90_RS05580	COG3383	formate dehydrogenase (NAD+) activity
C7J90_RS05605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7J90_RS05610	COG2076	Multidrug Resistance protein
C7J90_RS05615	COG2076	Multidrug Resistance protein
C7J90_RS05635	COG1757	Na H antiporter
C7J90_RS05640	COG3942	CHAP domain
C7J90_RS05665	COG1960	acyl-CoA dehydrogenase activity
C7J90_RS05670	COG2832	Protein of unknown function (DUF454)
C7J90_RS05675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7J90_RS05680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7J90_RS05690	COG2186	Transcriptional regulator
C7J90_RS05695	COG1940	carbohydrate kinase activity
C7J90_RS05700	COG1268	BioY protein
C7J90_RS05715	COG1609	Transcriptional regulator
C7J90_RS05720	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7J90_RS05725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7J90_RS05730	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7J90_RS05735	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7J90_RS05740	COG4149	molybdate abc transporter
C7J90_RS05745	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C7J90_RS05750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7J90_RS05755	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7J90_RS05770	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7J90_RS05785	COG0746	molybdenum cofactor guanylyltransferase activity
C7J90_RS05790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7J90_RS05815	COG2348	transferase activity, transferring amino-acyl groups
C7J90_RS05820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7J90_RS05825	COG0436	Aminotransferase
C7J90_RS05845	COG2252	PERMEase
C7J90_RS05860	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7J90_RS05865	COG0088	Forms part of the polypeptide exit tunnel
C7J90_RS05870	COG0089	rRNA binding
C7J90_RS05875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7J90_RS05880	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7J90_RS05885	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7J90_RS05890	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7J90_RS05900	COG0255	Belongs to the universal ribosomal protein uL29 family
C7J90_RS05910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7J90_RS05915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7J90_RS05925	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7J90_RS05930	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7J90_RS05950	COG1841	ribosomal large subunit assembly
C7J90_RS05955	COG0200	Binds to the 23S rRNA
C7J90_RS05960	COG0201	protein transport
C7J90_RS05975	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7J90_RS05990	COG0202	RNA polymerase activity
C7J90_RS05995	COG0203	ribosomal protein L17
C7J90_RS06005	COG1122	ATPase activity
C7J90_RS06015	COG0101	tRNA pseudouridine synthase activity
C7J90_RS06020	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7J90_RS06080	COG0789	Transcriptional regulator
C7J90_RS06105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7J90_RS06110	COG1131	(ABC) transporter
C7J90_RS06125	COG0745	RESPONSE REGULATOR receiver
C7J90_RS06140	COG1349	DNA-binding transcription factor activity
C7J90_RS06190	COG5002	protein histidine kinase activity
C7J90_RS06225	COG1764	response to oxidative stress
C7J90_RS06235	COG0710	3-dehydroquinate dehydratase activity
C7J90_RS06245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7J90_RS06250	COG1393	Belongs to the ArsC family
C7J90_RS06260	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7J90_RS06270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7J90_RS06275	COG2011	ABC-type metal ion transport system permease component
C7J90_RS06280	COG1464	Belongs to the NlpA lipoprotein family
C7J90_RS06285	COG1464	Belongs to the NlpA lipoprotein family
C7J90_RS06295	COG0396	ATPase activity
C7J90_RS06300	COG0719	Fe-S assembly protein
C7J90_RS06310	COG0822	iron-sulfur transferase activity
C7J90_RS06315	COG0719	Fe-S assembly protein
C7J90_RS06320	COG4536	flavin adenine dinucleotide binding
C7J90_RS06325	COG2070	2-Nitropropane dioxygenase
C7J90_RS06335	COG1801	Protein of unknown function DUF72
C7J90_RS06340	COG0730	response to heat
C7J90_RS06345	COG0737	Belongs to the 5'-nucleotidase family
C7J90_RS06350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7J90_RS06355	COG4470	Protein conserved in bacteria
C7J90_RS06360	COG0175	sulfate reduction
C7J90_RS06365	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7J90_RS06370	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7J90_RS06375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7J90_RS06390	COG0730	response to heat
C7J90_RS06395	COG2046	Belongs to the sulfate adenylyltransferase family
C7J90_RS06400	COG0529	Catalyzes the synthesis of activated sulfate
C7J90_RS06405	COG0706	membrane insertase activity
C7J90_RS06415	COG2445	Protein of unknown function DUF86
C7J90_RS06420	COG0647	UMP catabolic process
C7J90_RS06425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7J90_RS06430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7J90_RS06435	COG4837	Protein of unknown function (DUF1462)
C7J90_RS06440	COG1252	NADH dehydrogenase
C7J90_RS06445	COG4844	belongs to the
C7J90_RS06450	COG0316	Belongs to the HesB IscA family
C7J90_RS06455	COG3344	reverse transcriptase
C7J90_RS06460	COG1252	NADH dehydrogenase
C7J90_RS06465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7J90_RS06470	COG2056	Na+-H+ antiporter family
C7J90_RS06475	COG2050	protein possibly involved in aromatic compounds catabolism
C7J90_RS06480	COG1320	monovalent cation:proton antiporter activity
C7J90_RS06485	COG2212	antiporter activity
C7J90_RS06490	COG1863	multisubunit Na H antiporter MnhE subunit
C7J90_RS06495	COG0651	ATP synthesis coupled electron transport
C7J90_RS06500	COG1006	Multisubunit Na H antiporter MnhC subunit
C7J90_RS06505	COG2111	Na H antiporter
C7J90_RS06510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7J90_RS06510	COG2111	Na H antiporter
C7J90_RS06520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7J90_RS06540	COG1098	S1 RNA binding domain
C7J90_RS06545	COG1012	belongs to the aldehyde dehydrogenase family
C7J90_RS06565	COG0137	argininosuccinate synthase activity
C7J90_RS06570	COG0166	Belongs to the GPI family
C7J90_RS06585	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7J90_RS06595	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7J90_RS06605	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7J90_RS06610	COG0561	phosphatase activity
C7J90_RS06615	COG2151	metal-sulfur cluster biosynthetic enzyme
C7J90_RS06620	COG0542	response to heat
C7J90_RS06625	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C7J90_RS06650	COG0601	transmembrane transport
C7J90_RS06655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7J90_RS06660	COG0444	Belongs to the ABC transporter superfamily
C7J90_RS06665	COG4608	Belongs to the ABC transporter superfamily
C7J90_RS06670	COG4166	transmembrane transport
C7J90_RS06680	COG1393	Belongs to the ArsC family
C7J90_RS06695	COG1164	Oligoendopeptidase f
C7J90_RS06710	COG2346	COG2346, Truncated hemoglobins
C7J90_RS06715	COG4116	CYTH
C7J90_RS06725	COG2357	RelA SpoT domain protein
C7J90_RS06730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7J90_RS06735	COG0564	pseudouridine synthase activity
C7J90_RS06740	COG2239	Acts as a magnesium transporter
C7J90_RS06745	COG0475	glutathione-regulated potassium exporter activity
C7J90_RS06745	COG0569	domain protein
C7J90_RS06755	COG0628	permease
C7J90_RS06760	COG1115	amino acid carrier protein
C7J90_RS06765	COG2382	esterase
C7J90_RS06770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7J90_RS06775	COG3716	PTS system mannose fructose sorbose family IID component
C7J90_RS06780	COG3715	PTS system
C7J90_RS06785	COG3119	arylsulfatase activity
C7J90_RS06790	COG2814	Major facilitator Superfamily
C7J90_RS06795	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7J90_RS06800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7J90_RS06815	COG0861	Integral membrane protein TerC family
C7J90_RS06820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7J90_RS06820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7J90_RS06825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7J90_RS06830	COG0737	Belongs to the 5'-nucleotidase family
C7J90_RS06840	COG4873	Protein conserved in bacteria
C7J90_RS06905	COG2801	Transposase and inactivated derivatives
C7J90_RS06945	COG0456	acetyltransferase
C7J90_RS06950	COG4619	ABC transporter
C7J90_RS06955	COG0390	transport system, permease component
C7J90_RS06960	COG1575	Belongs to the MenA family. Type 1 subfamily
C7J90_RS06965	COG1169	isochorismate synthase
C7J90_RS06970	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7J90_RS06975	COG2267	carboxylic ester hydrolase activity
C7J90_RS06980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7J90_RS06985	COG0436	Aminotransferase
C7J90_RS06990	COG3594	Acyltransferase
C7J90_RS07015	COG1316	TRANSCRIPTIONal
C7J90_RS07020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7J90_RS07025	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C7J90_RS07045	COG0463	Glycosyl transferase, family 2
C7J90_RS07050	COG0438	transferase activity, transferring glycosyl groups
C7J90_RS07070	COG1134	teichoic acid transport
C7J90_RS07085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7J90_RS07090	COG1845	cytochrome c oxidase, subunit III
C7J90_RS07100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7J90_RS07110	COG1017	nitric oxide dioxygenase activity
C7J90_RS07110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7J90_RS07120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7J90_RS07125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7J90_RS07130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7J90_RS07135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7J90_RS07140	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7J90_RS07150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7J90_RS07155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7J90_RS07160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7J90_RS07170	COG0138	bifunctional purine biosynthesis protein purh
C7J90_RS07175	COG0151	Belongs to the GarS family
C7J90_RS07185	COG1122	ATPase activity
C7J90_RS07200	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7J90_RS07210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7J90_RS07245	COG1271	oxidase subunit
C7J90_RS07250	COG1294	oxidase, subunit
C7J90_RS07255	COG0569	domain protein
C7J90_RS07275	COG0242	peptide deformylase activity
C7J90_RS07305	COG4476	Belongs to the UPF0223 family
C7J90_RS07320	COG1176	ABC-type spermidine putrescine transport system, permease component I
C7J90_RS07325	COG1177	transmembrane transport
C7J90_RS07345	COG3344	reverse transcriptase
C7J90_RS07355	COG0483	inositol monophosphate 1-phosphatase activity
C7J90_RS07365	COG1217	gtp-binding protein TYPA
C7J90_RS07370	COG1902	pentaerythritol trinitrate reductase activity
C7J90_RS07375	COG4896	Protein conserved in bacteria
C7J90_RS07380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7J90_RS07385	COG4838	Belongs to the UPF0358 family
C7J90_RS07390	COG0772	Belongs to the SEDS family
C7J90_RS07400	COG1612	heme a metabolic process
C7J90_RS07405	COG0109	protoheme IX farnesyltransferase activity
C7J90_RS07420	COG3679	Belongs to the UPF0342 family
C7J90_RS07425	COG0584	glycerophosphoryl diester phosphodiesterase
C7J90_RS07430	COG4471	UPF0298 protein
C7J90_RS07440	COG0742	ribosomal rna small subunit methyltransferase
C7J90_RS07445	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7J90_RS07465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7J90_RS07470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7J90_RS07475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7J90_RS07480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7J90_RS07480	COG0072	phenylalanine-tRNA ligase activity
C7J90_RS07485	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7J90_RS07500	COG1796	DNA polymerase
C7J90_RS07500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7J90_RS07510	COG3118	belongs to the thioredoxin family
C7J90_RS07515	COG0322	excinuclease ABC activity
C7J90_RS07520	COG2009	succinate dehydrogenase
C7J90_RS07525	COG1053	succinate dehydrogenase
C7J90_RS07530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7J90_RS07550	COG0733	neurotransmitter:sodium symporter activity
C7J90_RS07565	COG1131	(ABC) transporter
C7J90_RS07585	COG0577	efflux transmembrane transporter activity
C7J90_RS07585	COG1136	(ABC) transporter
C7J90_RS07615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7J90_RS07645	COG1011	Hydrolase
C7J90_RS07650	COG0454	-acetyltransferase
C7J90_RS07655	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C7J90_RS07660	COG2001	Belongs to the MraZ family
C7J90_RS07665	COG0275	rRNA processing
C7J90_RS07670	COG4839	cell division protein FtsL
C7J90_RS07675	COG0768	penicillin binding
C7J90_RS07685	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7J90_RS07695	COG0849	cell division
C7J90_RS07700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7J90_RS07710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7J90_RS07715	COG1799	cell septum assembly
C7J90_RS07720	COG0762	integral membrane protein
C7J90_RS07730	COG3599	regulation of cell shape
C7J90_RS07735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7J90_RS07740	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7J90_RS07745	COG0564	pseudouridine synthase activity
C7J90_RS07750	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7J90_RS07760	COG0540	Belongs to the ATCase OTCase family
C7J90_RS07770	COG0505	Belongs to the CarA family
C7J90_RS07775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7J90_RS07780	COG0543	2 iron, 2 sulfur cluster binding
C7J90_RS07785	COG0167	dihydroorotate dehydrogenase activity
C7J90_RS07790	COG0284	orotidine-5'-phosphate decarboxylase activity
C7J90_RS07800	COG0546	phosphoglycolate phosphatase activity
C7J90_RS07810	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C7J90_RS07820	COG1758	RNA polymerase activity
C7J90_RS07825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7J90_RS07830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7J90_RS07840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7J90_RS07845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7J90_RS07845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7J90_RS07850	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7J90_RS07855	COG0631	protein serine/threonine phosphatase activity
C7J90_RS07865	COG2124	cytochrome p450
C7J90_RS07870	COG1162	GTPase activity
C7J90_RS07875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7J90_RS07885	COG2801	Transposase and inactivated derivatives
C7J90_RS07900	COG1302	Protein conserved in bacteria
C7J90_RS07910	COG1760	l-serine dehydratase
C7J90_RS07915	COG1760	l-serine dehydratase
C7J90_RS07925	COG1349	DNA-binding transcription factor activity
C7J90_RS07945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7J90_RS07950	COG0571	ribonuclease III activity
C7J90_RS07955	COG1196	nuclear chromosome segregation
C7J90_RS07960	COG0552	protein localization to endoplasmic reticulum
C7J90_RS07965	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7J90_RS07970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7J90_RS07975	COG0228	four-way junction DNA binding
C7J90_RS07980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7J90_RS07985	COG0336	Belongs to the RNA methyltransferase TrmD family
C7J90_RS08000	COG4485	Bacterial membrane protein, YfhO
C7J90_RS08015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7J90_RS08030	COG0045	succinate-CoA ligase (ADP-forming) activity
C7J90_RS08040	COG0758	DNA mediated transformation
C7J90_RS08045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7J90_RS08055	COG4974	Belongs to the 'phage' integrase family
C7J90_RS08065	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7J90_RS08070	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7J90_RS08075	COG0052	Belongs to the universal ribosomal protein uS2 family
C7J90_RS08085	COG0528	UMP kinase activity
C7J90_RS08090	COG0233	cytoplasmic translational termination
C7J90_RS08100	COG4589	Belongs to the CDS family
C7J90_RS08105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7J90_RS08115	COG0442	prolyl-tRNA aminoacylation
C7J90_RS08120	COG2176	DNA-directed DNA polymerase activity
C7J90_RS08125	COG0779	Required for maturation of 30S ribosomal subunits
C7J90_RS08130	COG0195	Participates in both transcription termination and antitermination
C7J90_RS08135	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7J90_RS08140	COG1358	cellular component organization or biogenesis
C7J90_RS08145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7J90_RS08150	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7J90_RS08155	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7J90_RS08160	COG0196	riboflavin kinase activity
C7J90_RS08170	COG1185	polyribonucleotide nucleotidyltransferase activity
C7J90_RS08185	COG2188	Transcriptional regulator
C7J90_RS08190	COG0612	Peptidase, M16
C7J90_RS08195	COG0612	Peptidase, M16
C7J90_RS08220	COG1058	Belongs to the CinA family
C7J90_RS08220	COG1546	Belongs to the CinA family
C7J90_RS08225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7J90_RS08230	COG1418	mRNA catabolic process
C7J90_RS08250	COG1692	metallophosphoesterase
C7J90_RS08255	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C7J90_RS08255	COG0674	pyruvate-flavodoxin oxidoreductase activity
C7J90_RS08260	COG1013	pyruvate-flavodoxin oxidoreductase activity
C7J90_RS08270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7J90_RS08275	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7J90_RS08290	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7J90_RS08295	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7J90_RS08300	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7J90_RS08305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7J90_RS08315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7J90_RS08325	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7J90_RS08330	COG1923	regulation of RNA biosynthetic process
C7J90_RS08335	COG0386	Belongs to the glutathione peroxidase family
C7J90_RS08340	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7J90_RS08345	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7J90_RS08350	COG0789	Transcriptional regulator
C7J90_RS08355	COG0174	glutamine synthetase
C7J90_RS08390	COG1525	nuclease
C7J90_RS08410	COG0527	aspartate kinase activity
C7J90_RS08415	COG0460	homoserine dehydrogenase
C7J90_RS08420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7J90_RS08425	COG0083	homoserine kinase activity
C7J90_RS08430	COG0561	phosphatase activity
C7J90_RS08440	COG0833	amino acid
C7J90_RS08445	COG0753	catalase activity
C7J90_RS08455	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7J90_RS08460	COG0516	GMP reductase activity
C7J90_RS08480	COG4224	UPF0291 protein
C7J90_RS08490	COG3763	UPF0154 protein
C7J90_RS08495	COG4846	Membrane protein involved in cytochrome C biogenesis
C7J90_RS08505	COG0420	3'-5' exonuclease activity
C7J90_RS08510	COG0419	ATPase involved in DNA repair
C7J90_RS08515	COG2801	Transposase and inactivated derivatives
C7J90_RS08525	COG1970	mechanosensitive ion channel activity
C7J90_RS08530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7J90_RS08540	COG0824	Thioesterase
C7J90_RS08545	COG4841	protein insertion into membrane
C7J90_RS08550	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7J90_RS08560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7J90_RS08565	COG1115	amino acid carrier protein
C7J90_RS08570	COG3711	transcriptional antiterminator
C7J90_RS08575	COG0628	permease
C7J90_RS08595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7J90_RS08600	COG0287	Prephenate dehydrogenase
C7J90_RS08605	COG2348	transferase activity, transferring amino-acyl groups
C7J90_RS08610	COG2348	transferase activity, transferring amino-acyl groups
C7J90_RS08625	COG2996	Protein conserved in bacteria
C7J90_RS08630	COG0488	(ABC) transporter
C7J90_RS08635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7J90_RS08640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7J90_RS08645	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7J90_RS08650	COG2171	N-acyltransferase activity
C7J90_RS08670	COG1278	Cold shock
C7J90_RS08690	COG3853	Toxic anion resistance protein (TelA)
C7J90_RS08695	COG1114	Component of the transport system for branched-chain amino acids
C7J90_RS08700	COG4548	von Willebrand factor, type A
C7J90_RS08705	COG0714	Associated with various cellular activities
C7J90_RS08725	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7J90_RS08735	COG5002	protein histidine kinase activity
C7J90_RS08745	COG0671	phosphoesterase, PA-phosphatase related
C7J90_RS08755	COG0793	Belongs to the peptidase S41A family
C7J90_RS08770	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7J90_RS08800	COG1413	lyase activity
C7J90_RS08810	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7J90_RS08815	COG0328	RNA-DNA hybrid ribonuclease activity
C7J90_RS08820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7J90_RS08825	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7J90_RS08830	COG2962	Rard protein
C7J90_RS08835	COG0116	Belongs to the methyltransferase superfamily
C7J90_RS08845	COG3599	regulation of cell shape
C7J90_RS08850	COG4474	Belongs to the UPF0398 family
C7J90_RS08865	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7J90_RS08865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7J90_RS08875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7J90_RS08880	COG3935	DnaD domain protein
C7J90_RS08885	COG0017	Asparaginyl-tRNA synthetase
C7J90_RS08890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7J90_RS08890	COG1199	ATP-dependent helicase activity
C7J90_RS08900	COG0617	tRNA 3'-terminal CCA addition
C7J90_RS08905	COG0438	transferase activity, transferring glycosyl groups
C7J90_RS08910	COG1694	Mazg nucleotide pyrophosphohydrolase
C7J90_RS08915	COG2738	Putative neutral zinc metallopeptidase
C7J90_RS08920	COG4347	Protein of unknown function (DUF1405)
C7J90_RS08930	COG0457	Tetratricopeptide repeat
C7J90_RS08940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7J90_RS08950	COG0105	UTP biosynthetic process
C7J90_RS08955	COG0142	geranyltranstransferase activity
C7J90_RS08960	COG2226	methyltransferase
C7J90_RS08975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7J90_RS08980	COG1160	GTP binding
C7J90_RS08985	COG0539	negative regulation of cytoplasmic translation
C7J90_RS08990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7J90_RS08995	COG0252	asparaginase activity
C7J90_RS09000	COG0492	ferredoxin-NADP+ reductase activity
C7J90_RS09010	COG0514	ATP-dependent DNA helicase (RecQ)
C7J90_RS09020	COG1141	Ferredoxin
C7J90_RS09035	COG5002	protein histidine kinase activity
C7J90_RS09040	COG0745	RESPONSE REGULATOR receiver
C7J90_RS09045	COG1187	pseudouridine synthase activity
C7J90_RS09050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7J90_RS09055	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7J90_RS09065	COG4974	Belongs to the 'phage' integrase family
C7J90_RS09070	COG0735	belongs to the Fur family
C7J90_RS09075	COG0494	nUDIX hydrolase
C7J90_RS09080	COG0667	Aldo Keto reductase
C7J90_RS09085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7J90_RS09090	COG1234	tRNA 3'-trailer cleavage
C7J90_RS09095	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7J90_RS09110	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7J90_RS09115	COG4129	membrane
C7J90_RS09125	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7J90_RS09130	COG0022	dehydrogenase e1 component
C7J90_RS09135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7J90_RS09140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7J90_RS09145	COG0497	DNA recombination
C7J90_RS09155	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7J90_RS09160	COG0142	geranyltranstransferase activity
C7J90_RS09170	COG1570	exodeoxyribonuclease VII activity
C7J90_RS09175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7J90_RS09180	COG1302	Protein conserved in bacteria
C7J90_RS09185	COG0439	Biotin carboxylase
C7J90_RS09190	COG0511	ligase activity, forming carbon-carbon bonds
C7J90_RS09195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7J90_RS09200	COG0006	proline dipeptidase activity
C7J90_RS09215	COG0095	Lipoate-protein ligase
C7J90_RS09220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7J90_RS09225	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7J90_RS09235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7J90_RS09240	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7J90_RS09260	COG4537	Required for transformation and DNA binding
C7J90_RS09270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7J90_RS09275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7J90_RS09280	COG0011	TIGRFAM Protein of
C7J90_RS09285	COG1940	carbohydrate kinase activity
C7J90_RS09290	COG4483	Protein conserved in bacteria
C7J90_RS09295	COG0705	Rhomboid family
C7J90_RS09300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7J90_RS09305	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7J90_RS09310	COG0704	Plays a role in the regulation of phosphate uptake
C7J90_RS09315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7J90_RS09320	COG0581	inorganic phosphate transmembrane transporter activity
C7J90_RS09325	COG0573	inorganic phosphate transmembrane transporter activity
C7J90_RS09330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7J90_RS09335	COG0768	penicillin binding
C7J90_RS09345	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7J90_RS09355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7J90_RS09360	COG1121	(ABC) transporter
C7J90_RS09365	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7J90_RS09370	COG0513	Belongs to the DEAD box helicase family
C7J90_RS09375	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7J90_RS09380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7J90_RS09385	COG2384	SAM-dependent methyltransferase
C7J90_RS09390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7J90_RS09395	COG0358	DNA primase activity
C7J90_RS09400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7J90_RS09405	COG0517	IMP dehydrogenase activity
C7J90_RS09410	COG0423	glycine-tRNA ligase activity
C7J90_RS09425	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7J90_RS09435	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7J90_RS09440	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7J90_RS09445	COG1702	phosphate starvation-inducible protein PhoH
C7J90_RS09455	COG4864	UPF0365 protein
C7J90_RS09460	COG1030	water channel activity
C7J90_RS09470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7J90_RS09475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7J90_RS09480	COG2264	protein methyltransferase activity
C7J90_RS09485	COG0484	heat shock protein binding
C7J90_RS09490	COG0443	Heat shock 70 kDa protein
C7J90_RS09495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7J90_RS09500	COG1420	regulation of RNA biosynthetic process
C7J90_RS09505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7J90_RS09510	COG0481	GTPase activity
C7J90_RS09515	COG0268	Binds directly to 16S ribosomal RNA
C7J90_RS09525	COG0658	competence protein
C7J90_RS09525	COG2333	competence protein COMEC
C7J90_RS09530	COG2131	deaminase
C7J90_RS09535	COG1555	photosystem II stabilization
C7J90_RS09545	COG0799	negative regulation of ribosome biogenesis
C7J90_RS09550	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7J90_RS09555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7J90_RS09560	COG1534	Rna-binding protein
C7J90_RS09565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7J90_RS09570	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7J90_RS09575	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7J90_RS09580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7J90_RS09585	COG1914	H( )-stimulated, divalent metal cation uptake system
C7J90_RS09590	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C7J90_RS09595	COG0439	Biotin carboxylase
C7J90_RS09600	COG0511	ligase activity, forming carbon-carbon bonds
C7J90_RS09605	COG1984	allophanate hydrolase subunit 2
C7J90_RS09610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7J90_RS09615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7J90_RS09620	COG0572	uridine kinase
C7J90_RS09625	COG0826	peptidase U32
C7J90_RS09630	COG0826	peptidase U32
C7J90_RS09635	COG4122	O-methyltransferase activity
C7J90_RS09640	COG3906	Belongs to the UPF0473 family
C7J90_RS09645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7J90_RS09650	COG4472	Bacterial protein of unknown function (DUF965)
C7J90_RS09655	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7J90_RS09660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7J90_RS09670	COG0482	sulfurtransferase activity
C7J90_RS09675	COG1104	cysteine desulfurase activity
C7J90_RS09680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7J90_RS09685	COG3237	CsbD-like
C7J90_RS09695	COG1959	2 iron, 2 sulfur cluster binding
C7J90_RS09700	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7J90_RS09705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7J90_RS09715	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7J90_RS09725	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7J90_RS09730	COG1490	D-aminoacyl-tRNA deacylase activity
C7J90_RS09735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7J90_RS09745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7J90_RS09745	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7J90_RS09750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7J90_RS09750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7J90_RS09755	COG1862	Preprotein translocase
C7J90_RS09760	COG0343	queuine tRNA-ribosyltransferase activity
C7J90_RS09765	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7J90_RS09770	COG2255	four-way junction helicase activity
C7J90_RS09775	COG0632	four-way junction helicase activity
C7J90_RS09780	COG4492	Belongs to the UPF0735 family
C7J90_RS09785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7J90_RS09795	COG2868	ribosomal protein
C7J90_RS09810	COG1792	Involved in formation and maintenance of cell shape
C7J90_RS09820	COG2003	Belongs to the UPF0758 family
C7J90_RS09865	COG2003	Belongs to the UPF0758 family
C7J90_RS09875	COG0285	dihydrofolate synthase activity
C7J90_RS09880	COG0525	valine-tRNA ligase activity
C7J90_RS09885	COG3180	Ammonia monooxygenase
C7J90_RS09890	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7J90_RS09905	COG0181	hydroxymethylbilane synthase activity
C7J90_RS09910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7J90_RS09920	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7J90_RS09925	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7J90_RS09930	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7J90_RS09940	COG4112	unkown
C7J90_RS09950	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7J90_RS09955	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7J90_RS09960	COG0833	amino acid
C7J90_RS09970	COG1484	DNA-dependent DNA replication
C7J90_RS09975	COG3611	Membrane attachment protein
C7J90_RS09985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7J90_RS09990	COG0237	dephospho-CoA kinase activity
C7J90_RS09995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7J90_RS10000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7J90_RS10000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7J90_RS10005	COG5002	protein histidine kinase activity
C7J90_RS10010	COG0745	RESPONSE REGULATOR receiver
C7J90_RS10015	COG0538	isocitrate dehydrogenase activity
C7J90_RS10020	COG0372	Belongs to the citrate synthase family
C7J90_RS10025	COG0469	pyruvate kinase activity
C7J90_RS10030	COG0205	6-phosphofructokinase activity
C7J90_RS10035	COG0825	malonyl-CoA metabolic process
C7J90_RS10040	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7J90_RS10045	COG0281	malic enzyme
C7J90_RS10050	COG0587	DNA-directed DNA polymerase activity
C7J90_RS10055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7J90_RS10060	COG4109	DRTGG domain
C7J90_RS10085	COG0589	response to stress
C7J90_RS10090	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7J90_RS10095	COG0827	DNA restriction-modification system
C7J90_RS10105	COG1714	RDD family
C7J90_RS10110	COG0616	signal peptide processing
C7J90_RS10115	COG0301	tRNA thio-modification
C7J90_RS10120	COG1104	cysteine desulfurase activity
C7J90_RS10125	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7J90_RS10130	COG1956	GAF domain-containing protein
C7J90_RS10135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7J90_RS10145	COG0584	glycerophosphoryl diester phosphodiesterase
C7J90_RS10160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7J90_RS10170	COG0204	Acyl-transferase
C7J90_RS10175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7J90_RS10185	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C7J90_RS10190	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7J90_RS10195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7J90_RS10200	COG0454	-acetyltransferase
C7J90_RS10205	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7J90_RS10210	COG1609	Transcriptional regulator
C7J90_RS10220	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7J90_RS10220	COG1605	Chorismate mutase
C7J90_RS10230	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7J90_RS10235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7J90_RS10240	COG1674	ftsk spoiiie
C7J90_RS10245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7J90_RS10255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7J90_RS10260	COG1363	Peptidase, m42
C7J90_RS10270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7J90_RS10275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7J90_RS10280	COG0510	thiamine kinase activity
C7J90_RS10285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7J90_RS10290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7J90_RS10300	COG1187	pseudouridine synthase activity
C7J90_RS10305	COG2244	polysaccharide biosynthetic process
C7J90_RS10310	COG2081	HI0933 family
C7J90_RS10315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7J90_RS10325	COG1242	4 iron, 4 sulfur cluster binding
C7J90_RS10330	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7J90_RS10340	COG0039	L-malate dehydrogenase activity
C7J90_RS10345	COG2267	carboxylic ester hydrolase activity
C7J90_RS10355	COG0506	proline dehydrogenase activity
C7J90_RS10360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7J90_RS10365	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7J90_RS10365	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7J90_RS10370	COG0307	riboflavin synthase, alpha
C7J90_RS10375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7J90_RS10375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7J90_RS10385	COG4193	domain, Protein
C7J90_RS10385	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7J90_RS10385	COG3266	domain, Protein
C7J90_RS10395	COG1595	DNA-templated transcription, initiation
C7J90_RS10415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7J90_RS10425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7J90_RS10430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7J90_RS10435	COG0656	L-ascorbic acid biosynthetic process
C7J90_RS10445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7J90_RS10450	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7J90_RS10455	COG1506	peptidase
C7J90_RS10465	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7J90_RS10475	COG0318	PFAM AMP-dependent synthetase and ligase
C7J90_RS10555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C7J90_RS10560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7J90_RS10565	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7J90_RS10575	COG3344	reverse transcriptase
C7J90_RS10580	COG4473	ABC transporter
C7J90_RS10585	COG1131	(ABC) transporter
C7J90_RS10590	COG0537	adenosine 5'-monophosphoramidase activity
C7J90_RS10600	COG1846	Transcriptional regulator
C7J90_RS10610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7J90_RS10620	COG4717	serine-type aminopeptidase activity
C7J90_RS10625	COG0420	3'-5' exonuclease activity
C7J90_RS10630	COG3679	Belongs to the UPF0342 family
C7J90_RS10635	COG4399	Belongs to the UPF0754 family
C7J90_RS10650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7J90_RS10655	COG2197	response regulator
C7J90_RS10660	COG4585	Histidine kinase
C7J90_RS10660	COG2203	Gaf domain
C7J90_RS10665	COG0564	pseudouridine synthase activity
C7J90_RS10670	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C7J90_RS10690	COG0363	glucosamine-6-phosphate deaminase activity
C7J90_RS10700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7J90_RS10705	COG1126	abc transporter atp-binding protein
C7J90_RS10710	COG0765	amino acid transport
C7J90_RS10930	COG0270	DNA (cytosine-5-)-methyltransferase activity
C7J90_RS10955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7J90_RS10965	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7J90_RS10970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7J90_RS10980	COG1780	Probably involved in ribonucleotide reductase function
C7J90_RS11025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7J90_RS11025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7J90_RS11105	COG4974	Belongs to the 'phage' integrase family
C7J90_RS11245	COG0735	belongs to the Fur family
C7J90_RS11250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7J90_RS11255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7J90_RS11260	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7J90_RS11265	COG4129	membrane
C7J90_RS11270	COG0069	glutamate synthase activity
C7J90_RS11280	COG3557	Belongs to the UPF0374 family
C7J90_RS11290	COG1988	membrane-bound metal-dependent
C7J90_RS11300	COG1388	LysM domain
C7J90_RS11300	COG1134	teichoic acid transport
C7J90_RS11310	COG2137	regulation of response to DNA damage stimulus
C7J90_RS11315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7J90_RS11320	COG0028	Belongs to the TPP enzyme family
C7J90_RS11325	COG2348	transferase activity, transferring amino-acyl groups
C7J90_RS11330	COG0693	protein deglycase activity
C7J90_RS11335	COG0535	radical SAM domain protein
C7J90_RS11340	COG1607	acyl-coa hydrolase
C7J90_RS11345	COG2309	aminopeptidase activity
C7J90_RS11350	COG4840	Belongs to the UPF0435 family
C7J90_RS11355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7J90_RS11365	COG1295	ribonuclease BN
C7J90_RS11370	COG0288	reversible hydration of carbon dioxide
C7J90_RS11375	COG2197	response regulator
C7J90_RS11395	COG0024	Methionine aminopeptidase
C7J90_RS11400	COG4129	membrane
C7J90_RS11415	COG1528	Iron-storage protein
C7J90_RS11425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7J90_RS11435	COG1597	lipid kinase activity
C7J90_RS11440	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7J90_RS11450	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7J90_RS11455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7J90_RS11460	COG4851	CamS sex pheromone cAM373 precursor
C7J90_RS11465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7J90_RS11470	COG0210	DNA helicase
C7J90_RS11475	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C7J90_RS11480	COG4496	protein, YerC YecD
C7J90_RS11495	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C7J90_RS11500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7J90_RS11505	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7J90_RS11515	COG0077	Prephenate dehydratase
C7J90_RS11525	COG1335	isochorismatase
C7J90_RS11530	COG1227	inorganic diphosphatase activity
C7J90_RS11540	COG1012	belongs to the aldehyde dehydrogenase family
C7J90_RS11545	COG2706	6-phosphogluconolactonase activity
C7J90_RS11580	COG2610	gluconate transmembrane transporter activity
C7J90_RS11590	COG1802	Transcriptional regulator
C7J90_RS11600	COG1131	(ABC) transporter
C7J90_RS11615	COG1131	(ABC) transporter
C7J90_RS11620	COG1725	Transcriptional regulator
C7J90_RS11625	COG0436	Aminotransferase
C7J90_RS11635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7J90_RS11640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7J90_RS11690	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7J90_RS11715	COG4512	PFAM Accessory gene regulator B
C7J90_RS11735	COG1621	beta-fructofuranosidase activity
C7J90_RS11740	COG0425	Belongs to the sulfur carrier protein TusA family
C7J90_RS11745	COG2391	methyltransferase activity
C7J90_RS11750	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7J90_RS11755	COG0488	(ABC) transporter
C7J90_RS11760	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7J90_RS11765	COG0456	acetyltransferase
C7J90_RS11770	COG1214	PFAM Peptidase M22, glycoprotease
C7J90_RS11775	COG0802	atpase or kinase
C7J90_RS11780	COG0129	dihydroxy-acid dehydratase activity
C7J90_RS11785	COG0028	Belongs to the TPP enzyme family
C7J90_RS11795	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7J90_RS11800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7J90_RS11805	COG0473	3-isopropylmalate dehydrogenase activity
C7J90_RS11810	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7J90_RS11815	COG0066	3-isopropylmalate dehydratase activity
C7J90_RS11820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA