locus-tag	class	description
EQ029_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EQ029_RS00010	COG0592	DNA-directed DNA polymerase activity
EQ029_RS00015	COG2501	S4 domain
EQ029_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EQ029_RS00025	COG0187	DNA topoisomerase II activity
EQ029_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQ029_RS00035	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EQ029_RS00040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EQ029_RS00045	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EQ029_RS00055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EQ029_RS00065	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EQ029_RS00070	COG0359	binds to the 23S rRNA
EQ029_RS00075	COG0305	Participates in initiation and elongation during chromosome replication
EQ029_RS00080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EQ029_RS00095	COG0745	RESPONSE REGULATOR receiver
EQ029_RS00100	COG5002	protein histidine kinase activity
EQ029_RS00105	COG4863	YycH protein
EQ029_RS00115	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EQ029_RS00120	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EQ029_RS00140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQ029_RS00155	COG2217	Heavy metal translocating P-type atpase
EQ029_RS00160	COG1388	LysM domain
EQ029_RS00165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EQ029_RS00310	COG0668	transmembrane transport
EQ029_RS00325	COG0523	cobalamin synthesis protein
EQ029_RS00330	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQ029_RS00340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EQ029_RS00360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EQ029_RS00380	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EQ029_RS00390	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQ029_RS00395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQ029_RS00400	COG1121	(ABC) transporter
EQ029_RS00405	COG0523	cobalamin synthesis protein
EQ029_RS00410	COG1114	Component of the transport system for branched-chain amino acids
EQ029_RS00420	COG0747	negative chemotaxis
EQ029_RS00430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQ029_RS00435	COG4172	Belongs to the ABC transporter superfamily
EQ029_RS00465	COG0789	Transcriptional regulator
EQ029_RS00475	COG1253	flavin adenine dinucleotide binding
EQ029_RS00485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EQ029_RS00500	COG1113	amino acid transport
EQ029_RS00505	COG0778	Nitroreductase
EQ029_RS00550	COG1609	Transcriptional regulator
EQ029_RS00555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQ029_RS00560	COG1869	D-ribose catabolic process
EQ029_RS00565	COG1129	ABC transporter
EQ029_RS00570	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQ029_RS00575	COG1879	ABC-type sugar transport system periplasmic component
EQ029_RS00585	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EQ029_RS00590	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EQ029_RS00595	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EQ029_RS00605	COG1876	peptidase activity
EQ029_RS00610	COG1737	Transcriptional regulator
EQ029_RS00615	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQ029_RS00620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQ029_RS00625	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQ029_RS00640	COG2971	BadF BadG BcrA BcrD
EQ029_RS00650	COG3152	Membrane
EQ029_RS00660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EQ029_RS00670	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQ029_RS00675	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQ029_RS00680	COG1288	antiporter activity
EQ029_RS00695	COG2318	DinB family
EQ029_RS00715	COG1028	Short-chain dehydrogenase reductase Sdr
EQ029_RS00735	COG1012	belongs to the aldehyde dehydrogenase family
EQ029_RS00740	COG1063	alcohol dehydrogenase
EQ029_RS00745	COG1846	Transcriptional regulator
EQ029_RS00750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQ029_RS00765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EQ029_RS00775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQ029_RS00780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQ029_RS00785	COG0022	dehydrogenase e1 component
EQ029_RS00790	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQ029_RS00795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQ029_RS00800	COG1695	Transcriptional regulator
EQ029_RS00815	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EQ029_RS00820	COG2962	Rard protein
EQ029_RS00830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQ029_RS00880	COG0789	Transcriptional regulator
EQ029_RS00900	COG2314	TM2 domain
EQ029_RS00910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EQ029_RS00915	COG0549	Belongs to the carbamate kinase family
EQ029_RS00925	COG3093	addiction module antidote protein HigA
EQ029_RS00955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQ029_RS00965	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EQ029_RS00975	COG0471	metal ion transport
EQ029_RS00980	COG5505	Protein of unknown function (DUF819)
EQ029_RS00985	COG4336	lyase activity
EQ029_RS01000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EQ029_RS01010	COG0363	glucosamine-6-phosphate deaminase activity
EQ029_RS01015	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EQ029_RS01030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQ029_RS01035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQ029_RS01060	COG1124	(ABC) transporter
EQ029_RS01065	COG0444	Belongs to the ABC transporter superfamily
EQ029_RS01075	COG0601	transmembrane transport
EQ029_RS01080	COG0747	negative chemotaxis
EQ029_RS01085	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EQ029_RS01105	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EQ029_RS01115	COG1054	Belongs to the UPF0176 family
EQ029_RS01120	COG3386	PFAM SMP-30 Gluconolaconase
EQ029_RS01125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQ029_RS01145	COG4716	Myosin-crossreactive antigen
EQ029_RS01150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQ029_RS01155	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EQ029_RS01165	COG1131	(ABC) transporter
EQ029_RS01175	COG1476	TRANSCRIPTIONal
EQ029_RS01180	COG1959	2 iron, 2 sulfur cluster binding
EQ029_RS01185	COG0697	spore germination
EQ029_RS01190	COG2814	Major facilitator Superfamily
EQ029_RS01200	COG0737	Belongs to the 5'-nucleotidase family
EQ029_RS01210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EQ029_RS01215	COG3639	organic phosphonate transmembrane transporter activity
EQ029_RS01245	COG0201	protein transport
EQ029_RS01255	COG1073	alpha beta
EQ029_RS01265	COG0653	protein targeting
EQ029_RS01280	COG0642	Histidine kinase
EQ029_RS01285	COG0745	RESPONSE REGULATOR receiver
EQ029_RS01305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQ029_RS01325	COG2814	Major facilitator Superfamily
EQ029_RS01335	COG2113	Glycine betaine
EQ029_RS01340	COG2409	Drug exporters of the RND superfamily
EQ029_RS01345	COG0583	DNA-binding transcription factor activity
EQ029_RS01350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EQ029_RS01360	COG1288	antiporter activity
EQ029_RS01365	COG1263	PTS System
EQ029_RS01365	COG2190	(PTS) system
EQ029_RS01365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ029_RS01370	COG3942	CHAP domain
EQ029_RS01370	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQ029_RS01370	COG3942	CHAP domain
EQ029_RS01370	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQ029_RS01420	COG2235	arginine
EQ029_RS01430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQ029_RS01455	COG5658	integral membrane protein
EQ029_RS01460	COG2843	Capsule synthesis protein
EQ029_RS01465	COG1045	serine acetyltransferase
EQ029_RS01470	COG3961	Belongs to the TPP enzyme family
EQ029_RS01480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EQ029_RS01525	COG1216	Glycosyl transferase, family 2
EQ029_RS01525	COG0463	Glycosyl transferase, family 2
EQ029_RS01530	COG0110	maltose O-acetyltransferase activity
EQ029_RS01550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EQ029_RS01560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EQ029_RS01565	COG1316	TRANSCRIPTIONal
EQ029_RS01570	COG1785	Belongs to the alkaline phosphatase family
EQ029_RS01580	COG2205	protein histidine kinase activity
EQ029_RS01585	COG1136	(ABC) transporter
EQ029_RS01615	COG0175	sulfate reduction
EQ029_RS01620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EQ029_RS01625	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQ029_RS01640	COG0730	response to heat
EQ029_RS01645	COG2046	Belongs to the sulfate adenylyltransferase family
EQ029_RS01650	COG0529	Catalyzes the synthesis of activated sulfate
EQ029_RS01655	COG2851	Citrate transporter
EQ029_RS01670	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EQ029_RS01675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQ029_RS01680	COG1510	regulation of RNA biosynthetic process
EQ029_RS01685	COG1012	belongs to the aldehyde dehydrogenase family
EQ029_RS01690	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EQ029_RS01700	COG1473	amidohydrolase
EQ029_RS01710	COG1473	amidohydrolase
EQ029_RS01725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQ029_RS01735	COG0583	DNA-binding transcription factor activity
EQ029_RS01740	COG0574	Belongs to the PEP-utilizing enzyme family
EQ029_RS01740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EQ029_RS01745	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EQ029_RS01750	COG0579	oxidoreductase
EQ029_RS01755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQ029_RS01775	COG3588	fructose-bisphosphate aldolase
EQ029_RS01780	COG0563	adenylate kinase activity
EQ029_RS01805	COG1464	Belongs to the NlpA lipoprotein family
EQ029_RS01815	COG0531	amino acid
EQ029_RS01820	COG0028	Belongs to the TPP enzyme family
EQ029_RS01825	COG3527	Alpha-acetolactate decarboxylase
EQ029_RS01855	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EQ029_RS01865	COG0167	dihydroorotate dehydrogenase activity
EQ029_RS01870	COG3001	Fructosamine kinase
EQ029_RS01890	COG0596	Alpha beta hydrolase
EQ029_RS01925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQ029_RS01950	COG0741	lytic transglycosylase activity
EQ029_RS01960	COG1233	COG1233 Phytoene dehydrogenase and related
EQ029_RS01965	COG0463	Glycosyl transferase, family 2
EQ029_RS01970	COG1562	ergosterol biosynthetic process
EQ029_RS01975	COG1233	COG1233 Phytoene dehydrogenase and related
EQ029_RS01980	COG0436	Aminotransferase
EQ029_RS01990	COG2608	mercury ion transmembrane transporter activity
EQ029_RS01995	COG2217	Heavy metal translocating P-type atpase
EQ029_RS02005	COG1028	Short-chain dehydrogenase reductase Sdr
EQ029_RS02010	COG0110	maltose O-acetyltransferase activity
EQ029_RS02015	COG1012	belongs to the aldehyde dehydrogenase family
EQ029_RS02035	COG0598	Magnesium transport protein CorA
EQ029_RS02045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EQ029_RS02050	COG3425	synthase
EQ029_RS02065	COG1388	LysM domain
EQ029_RS02065	COG3942	CHAP domain
EQ029_RS02075	COG0583	DNA-binding transcription factor activity
EQ029_RS02085	COG1380	Effector of murein hydrolase LrgA
EQ029_RS02090	COG1346	cytolysis
EQ029_RS02095	COG0028	Belongs to the TPP enzyme family
EQ029_RS02105	COG1263	PTS System
EQ029_RS02105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ029_RS02105	COG2190	(PTS) system
EQ029_RS02110	COG1063	alcohol dehydrogenase
EQ029_RS02120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQ029_RS02125	COG0039	L-malate dehydrogenase activity
EQ029_RS02135	COG0697	spore germination
EQ029_RS02155	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQ029_RS02175	COG1070	Carbohydrate kinase
EQ029_RS02185	COG1760	l-serine dehydratase
EQ029_RS02190	COG1760	l-serine dehydratase
EQ029_RS02205	COG3764	Sortase (surface protein transpeptidase)
EQ029_RS02220	COG0778	Nitroreductase
EQ029_RS02225	COG1012	belongs to the aldehyde dehydrogenase family
EQ029_RS02235	COG2514	catechol 2,3-dioxygenase activity
EQ029_RS02250	COG1012	belongs to the aldehyde dehydrogenase family
EQ029_RS02255	COG1846	Transcriptional regulator
EQ029_RS02260	COG0346	lactoylglutathione lyase activity
EQ029_RS02265	COG0346	lactoylglutathione lyase activity
EQ029_RS02270	COG0400	carboxylic ester hydrolase activity
EQ029_RS02275	COG3949	Membrane
EQ029_RS02285	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EQ029_RS02290	COG0586	Pfam SNARE associated Golgi protein
EQ029_RS02300	COG2022	thiamine diphosphate biosynthetic process
EQ029_RS02305	COG2104	thiamine diphosphate biosynthetic process
EQ029_RS02305	COG2022	thiamine diphosphate biosynthetic process
EQ029_RS02310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQ029_RS02320	COG2271	Major facilitator Superfamily
EQ029_RS02335	COG4876	unkown
EQ029_RS02340	COG2357	RelA SpoT domain protein
EQ029_RS02350	COG0789	Transcriptional regulator
EQ029_RS02355	COG1802	Transcriptional regulator
EQ029_RS02360	COG1070	Carbohydrate kinase
EQ029_RS02365	COG2610	gluconate transmembrane transporter activity
EQ029_RS02380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQ029_RS02385	COG0494	nUDIX hydrolase
EQ029_RS02410	COG4221	oxidoreductase activity
EQ029_RS02415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQ029_RS02420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EQ029_RS02430	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EQ029_RS02435	COG1028	Short-chain dehydrogenase reductase Sdr
EQ029_RS02440	COG1363	Peptidase, m42
EQ029_RS02455	COG0069	glutamate synthase activity
EQ029_RS02470	COG4619	ABC transporter
EQ029_RS02475	COG0390	transport system, permease component
EQ029_RS02480	COG2205	protein histidine kinase activity
EQ029_RS02485	COG0745	RESPONSE REGULATOR receiver
EQ029_RS02495	COG2814	Major facilitator Superfamily
EQ029_RS02500	COG2272	Belongs to the type-B carboxylesterase lipase family
EQ029_RS02505	COG0531	amino acid
EQ029_RS02510	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EQ029_RS02515	COG1063	alcohol dehydrogenase
EQ029_RS02535	COG1174	glycine betaine transport
EQ029_RS02540	COG1346	cytolysis
EQ029_RS02545	COG1380	Effector of murein hydrolase LrgA
EQ029_RS02550	COG3279	Response regulator of the LytR AlgR family
EQ029_RS02555	COG3275	phosphorelay sensor kinase activity
EQ029_RS02565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EQ029_RS02570	COG3477	response to acidic pH
EQ029_RS02580	COG0706	membrane insertase activity
EQ029_RS02590	COG0531	amino acid
EQ029_RS02600	COG1113	amino acid transport
EQ029_RS02620	COG2226	methyltransferase
EQ029_RS02625	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EQ029_RS02630	COG2814	Major facilitator Superfamily
EQ029_RS02640	COG1929	Belongs to the glycerate kinase type-1 family
EQ029_RS02655	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EQ029_RS02660	COG0741	lytic transglycosylase activity
EQ029_RS02665	COG0588	phosphoglycerate mutase activity
EQ029_RS02675	COG2814	Major facilitator Superfamily
EQ029_RS02680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQ029_RS02685	COG0765	amino acid transport
EQ029_RS02690	COG1126	abc transporter atp-binding protein
EQ029_RS02710	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQ029_RS02710	COG3443	Belongs to the bacterial solute-binding protein 9 family
EQ029_RS02715	COG2353	YceI-like domain
EQ029_RS02740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQ029_RS02745	COG2146	nitrite reductase [NAD(P)H] activity
EQ029_RS02755	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EQ029_RS02760	COG1140	nitrate reductase beta subunit
EQ029_RS02765	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EQ029_RS02770	COG2181	nitrate reductase activity
EQ029_RS02780	COG4585	Histidine kinase
EQ029_RS02785	COG2197	response regulator
EQ029_RS02790	COG2223	nitrite transmembrane transporter activity
EQ029_RS02800	COG1846	Transcriptional regulator
EQ029_RS02825	COG3871	stress protein (general stress protein 26)
EQ029_RS02840	COG1263	PTS System
EQ029_RS02840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ029_RS02885	COG0492	ferredoxin-NADP+ reductase activity
EQ029_RS02895	COG0604	alcohol dehydrogenase
EQ029_RS02900	COG2822	iron ion transport
EQ029_RS02905	COG2837	iron assimilation
EQ029_RS02910	COG0672	)-iron permease
EQ029_RS02915	COG0805	protein transport
EQ029_RS02920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EQ029_RS02930	COG0463	Glycosyl transferase, family 2
EQ029_RS02930	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQ029_RS02935	COG1620	l-lactate permease
EQ029_RS02940	COG0438	transferase activity, transferring glycosyl groups
EQ029_RS02945	COG0579	oxidoreductase
EQ029_RS02960	COG3850	Histidine kinase
EQ029_RS02960	COG5002	protein histidine kinase activity
EQ029_RS02965	COG0745	RESPONSE REGULATOR receiver
EQ029_RS02970	COG0577	efflux transmembrane transporter activity
EQ029_RS02975	COG1136	(ABC) transporter
EQ029_RS02990	COG4640	response to antibiotic
EQ029_RS02995	COG2814	Major facilitator Superfamily
EQ029_RS03005	COG1566	PFAM secretion protein HlyD family protein
EQ029_RS03010	COG2814	Major facilitator Superfamily
EQ029_RS03035	COG0598	Magnesium transport protein CorA
EQ029_RS03040	COG1304	FMN binding
EQ029_RS03045	COG0786	glutamate:sodium symporter activity
EQ029_RS03050	COG2094	Belongs to the DNA glycosylase MPG family
EQ029_RS03065	COG1742	UPF0060 membrane protein
EQ029_RS03080	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EQ029_RS03085	COG1266	CAAX protease self-immunity
EQ029_RS03090	COG0010	Belongs to the arginase family
EQ029_RS03095	COG0659	secondary active sulfate transmembrane transporter activity
EQ029_RS03100	COG1473	amidohydrolase
EQ029_RS03105	COG1028	Short-chain dehydrogenase reductase Sdr
EQ029_RS03110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EQ029_RS03125	COG1737	Transcriptional regulator
EQ029_RS03130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ029_RS03130	COG1263	PTS System
EQ029_RS03140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQ029_RS03160	COG1113	amino acid transport
EQ029_RS03170	COG1263	PTS System
EQ029_RS03170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ029_RS03175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EQ029_RS03190	COG2378	regulation of single-species biofilm formation
EQ029_RS03200	COG1316	TRANSCRIPTIONal
EQ029_RS03205	COG3383	formate dehydrogenase (NAD+) activity
EQ029_RS03210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EQ029_RS03230	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQ029_RS03235	COG2076	Multidrug Resistance protein
EQ029_RS03240	COG2076	Multidrug Resistance protein
EQ029_RS03245	COG3942	CHAP domain
EQ029_RS03260	COG1757	Na H antiporter
EQ029_RS03270	COG3942	CHAP domain
EQ029_RS03295	COG1960	acyl-CoA dehydrogenase activity
EQ029_RS03300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQ029_RS03305	COG1957	nucleoside hydrolase
EQ029_RS03310	COG1268	BioY protein
EQ029_RS03320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EQ029_RS03325	COG0725	ABC transporter, periplasmic molybdate-binding protein
EQ029_RS03330	COG4149	molybdate abc transporter
EQ029_RS03335	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EQ029_RS03340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQ029_RS03350	COG0315	cyclic pyranopterin monophosphate synthase activity
EQ029_RS03375	COG0746	molybdenum cofactor guanylyltransferase activity
EQ029_RS03380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EQ029_RS03410	COG2348	transferase activity, transferring amino-acyl groups
EQ029_RS03415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQ029_RS03435	COG4975	Glucose uptake
EQ029_RS03445	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQ029_RS03445	COG0551	DNA topoisomerase type I activity
EQ029_RS03450	COG2252	PERMEase
EQ029_RS03465	COG0051	transcription antitermination factor activity, RNA binding
EQ029_RS03470	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EQ029_RS03475	COG0088	Forms part of the polypeptide exit tunnel
EQ029_RS03480	COG0089	rRNA binding
EQ029_RS03485	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EQ029_RS03490	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EQ029_RS03495	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EQ029_RS03500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EQ029_RS03505	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EQ029_RS03510	COG0255	Belongs to the universal ribosomal protein uL29 family
EQ029_RS03515	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EQ029_RS03520	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EQ029_RS03525	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EQ029_RS03530	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EQ029_RS03540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EQ029_RS03545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EQ029_RS03550	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EQ029_RS03555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EQ029_RS03560	COG1841	ribosomal large subunit assembly
EQ029_RS03565	COG0200	Binds to the 23S rRNA
EQ029_RS03570	COG0201	protein transport
EQ029_RS03575	COG0563	adenylate kinase activity
EQ029_RS03580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EQ029_RS03585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EQ029_RS03590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EQ029_RS03600	COG0202	RNA polymerase activity
EQ029_RS03605	COG0203	ribosomal protein L17
EQ029_RS03610	COG1122	ATPase activity
EQ029_RS03615	COG1122	ATPase activity
EQ029_RS03625	COG0101	tRNA pseudouridine synthase activity
EQ029_RS03630	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EQ029_RS03635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EQ029_RS03640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EQ029_RS03645	COG1349	DNA-binding transcription factor activity
EQ029_RS03650	COG0698	ribose 5-phosphate isomerase
EQ029_RS03655	COG0698	ribose 5-phosphate isomerase
EQ029_RS03660	COG1105	Belongs to the carbohydrate kinase PfkB family
EQ029_RS03665	COG3684	Belongs to the aldolase LacD family
EQ029_RS03670	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQ029_RS03675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQ029_RS03675	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQ029_RS03680	COG2723	6-phospho-beta-galactosidase activity
EQ029_RS03690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQ029_RS03695	COG0604	alcohol dehydrogenase
EQ029_RS03700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQ029_RS03715	COG1302	Protein conserved in bacteria
EQ029_RS03720	COG4264	IucA IucC family
EQ029_RS03725	COG2814	Major facilitator Superfamily
EQ029_RS03735	COG3457	Alanine racemase
EQ029_RS03740	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EQ029_RS03745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ029_RS03750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ029_RS03755	COG3314	Sporulation integral membrane protein YlbJ
EQ029_RS03760	COG2329	Antibiotic biosynthesis monooxygenase
EQ029_RS03770	COG1988	membrane-bound metal-dependent
EQ029_RS03775	COG4284	Utp--glucose-1-phosphate uridylyltransferase
EQ029_RS03780	COG1272	protein, Hemolysin III
EQ029_RS03795	COG2814	Major facilitator Superfamily
EQ029_RS03800	COG0489	protein tyrosine kinase activity
EQ029_RS03855	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EQ029_RS03865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQ029_RS03875	COG1119	ATPase activity
EQ029_RS03880	COG0561	phosphatase activity
EQ029_RS03900	COG0640	Transcriptional regulator
EQ029_RS03905	COG0702	epimerase
EQ029_RS03910	COG1482	cell wall glycoprotein biosynthetic process
EQ029_RS03930	COG0783	Belongs to the Dps family
EQ029_RS03935	COG0813	purine-nucleoside phosphorylase activity
EQ029_RS03940	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EQ029_RS03945	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EQ029_RS03950	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EQ029_RS03960	COG1854	S-ribosylhomocysteine lyase activity
EQ029_RS03980	COG5146	pantothenate kinase activity
EQ029_RS03995	COG0504	CTP synthase activity
EQ029_RS04005	COG0191	fructose-bisphosphate aldolase activity
EQ029_RS04010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQ029_RS04020	COG1012	belongs to the aldehyde dehydrogenase family
EQ029_RS04025	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EQ029_RS04030	COG0254	rRNA binding
EQ029_RS04035	COG1435	thymidine kinase activity
EQ029_RS04040	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EQ029_RS04045	COG2890	protein-(glutamine-N5) methyltransferase activity
EQ029_RS04050	COG0009	L-threonylcarbamoyladenylate synthase
EQ029_RS04055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQ029_RS04060	COG4475	Protein of unknown function (DUF436)
EQ029_RS04065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EQ029_RS04070	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EQ029_RS04075	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EQ029_RS04085	COG0356	it plays a direct role in the translocation of protons across the membrane
EQ029_RS04090	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQ029_RS04095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EQ029_RS04100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQ029_RS04105	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EQ029_RS04110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EQ029_RS04115	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EQ029_RS04120	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EQ029_RS04130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQ029_RS04135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EQ029_RS04145	COG0629	single-stranded DNA binding
EQ029_RS04150	COG1388	LysM domain
EQ029_RS04155	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EQ029_RS04165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EQ029_RS04170	COG0352	thiamine-phosphate diphosphorylase activity
EQ029_RS04175	COG0706	membrane insertase activity
EQ029_RS04185	COG1418	mRNA catabolic process
EQ029_RS04190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQ029_RS04195	COG1937	Protein conserved in bacteria
EQ029_RS04215	COG0772	Belongs to the SEDS family
EQ029_RS04220	COG1181	Belongs to the D-alanine--D-alanine ligase family
EQ029_RS04225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EQ029_RS04230	COG0513	Belongs to the DEAD box helicase family
EQ029_RS04240	COG3428	Bacterial PH domain
EQ029_RS04245	COG3402	PFAM membrane-flanked domain
EQ029_RS04250	COG0736	holo-[acyl-carrier-protein] synthase activity
EQ029_RS04255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQ029_RS04265	COG2337	Toxic component of a toxin-antitoxin (TA) module
EQ029_RS04270	COG2208	phosphoserine phosphatase activity
EQ029_RS04285	COG1191	sigma factor activity
EQ029_RS04290	COG2183	response to ionizing radiation
EQ029_RS04330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EQ029_RS04335	COG0066	3-isopropylmalate dehydratase activity
EQ029_RS04340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EQ029_RS04345	COG0473	3-isopropylmalate dehydrogenase activity
EQ029_RS04350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EQ029_RS04355	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EQ029_RS04360	COG0440	acetolactate synthase activity
EQ029_RS04365	COG0028	Belongs to the TPP enzyme family
EQ029_RS04370	COG0129	dihydroxy-acid dehydratase activity
EQ029_RS04375	COG0802	atpase or kinase
EQ029_RS04380	COG1214	PFAM Peptidase M22, glycoprotease
EQ029_RS04385	COG0456	acetyltransferase
EQ029_RS04390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EQ029_RS04400	COG0488	(ABC) transporter
EQ029_RS04405	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EQ029_RS04410	COG2391	methyltransferase activity
EQ029_RS04415	COG0425	Belongs to the sulfur carrier protein TusA family
EQ029_RS04420	COG0004	ammonium transporteR
EQ029_RS04425	COG1609	Transcriptional regulator
EQ029_RS04430	COG1621	beta-fructofuranosidase activity
EQ029_RS04435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQ029_RS04440	COG3279	Response regulator of the LytR AlgR family
EQ029_RS04455	COG4512	PFAM Accessory gene regulator B
EQ029_RS04480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EQ029_RS04485	COG0459	protein refolding
EQ029_RS04490	COG0582	viral genome integration into host DNA
EQ029_RS04550	COG1725	Transcriptional regulator
EQ029_RS04565	COG1131	(ABC) transporter
EQ029_RS04605	COG2706	6-phosphogluconolactonase activity
EQ029_RS04610	COG1012	belongs to the aldehyde dehydrogenase family
EQ029_RS04615	COG1227	inorganic diphosphatase activity
EQ029_RS04620	COG1335	isochorismatase
EQ029_RS04630	COG1605	Chorismate mutase
EQ029_RS04630	COG0077	Prephenate dehydratase
EQ029_RS04640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EQ029_RS04645	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EQ029_RS04650	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EQ029_RS04660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EQ029_RS04665	COG4496	protein, YerC YecD
EQ029_RS04670	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EQ029_RS04675	COG0210	DNA helicase
EQ029_RS04680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EQ029_RS04685	COG4851	CamS sex pheromone cAM373 precursor
EQ029_RS04690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQ029_RS04695	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQ029_RS04700	COG0154	amidase activity
EQ029_RS04705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQ029_RS04710	COG1597	lipid kinase activity
EQ029_RS04715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQ029_RS04725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQ029_RS04735	COG1528	Iron-storage protein
EQ029_RS04750	COG4129	membrane
EQ029_RS04755	COG0024	Methionine aminopeptidase
EQ029_RS04760	COG4221	oxidoreductase activity
EQ029_RS04780	COG4585	Histidine kinase
EQ029_RS04785	COG2197	response regulator
EQ029_RS04790	COG1295	ribonuclease BN
EQ029_RS04800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQ029_RS04805	COG4840	Belongs to the UPF0435 family
EQ029_RS04810	COG2309	aminopeptidase activity
EQ029_RS04815	COG1607	acyl-coa hydrolase
EQ029_RS04825	COG0535	radical SAM domain protein
EQ029_RS04835	COG0693	protein deglycase activity
EQ029_RS04840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQ029_RS04845	COG2137	regulation of response to DNA damage stimulus
EQ029_RS04855	COG1134	teichoic acid transport
EQ029_RS04855	COG1388	LysM domain
EQ029_RS04865	COG1988	membrane-bound metal-dependent
EQ029_RS04870	COG1194	a g-specific adenine glycosylase
EQ029_RS04875	COG3557	Belongs to the UPF0374 family
EQ029_RS04885	COG4129	membrane
EQ029_RS04890	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EQ029_RS04895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EQ029_RS04900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQ029_RS04905	COG0735	belongs to the Fur family
EQ029_RS05065	COG0765	amino acid transport
EQ029_RS05070	COG1126	abc transporter atp-binding protein
EQ029_RS05075	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EQ029_RS05085	COG0363	glucosamine-6-phosphate deaminase activity
EQ029_RS05100	COG0114	fumarate hydratase activity
EQ029_RS05105	COG0564	pseudouridine synthase activity
EQ029_RS05110	COG4585	Histidine kinase
EQ029_RS05110	COG2203	Gaf domain
EQ029_RS05115	COG2197	response regulator
EQ029_RS05125	COG4399	Belongs to the UPF0754 family
EQ029_RS05130	COG3679	Belongs to the UPF0342 family
EQ029_RS05140	COG4717	serine-type aminopeptidase activity
EQ029_RS05145	COG3481	metal-dependent phosphohydrolase, HD sub domain
EQ029_RS05150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQ029_RS05165	COG0537	adenosine 5'-monophosphoramidase activity
EQ029_RS05170	COG1131	(ABC) transporter
EQ029_RS05175	COG4473	ABC transporter
EQ029_RS05185	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EQ029_RS05190	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EQ029_RS05195	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EQ029_RS05245	COG0318	PFAM AMP-dependent synthetase and ligase
EQ029_RS05255	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EQ029_RS05260	COG0494	nUDIX hydrolase
EQ029_RS05265	COG1506	peptidase
EQ029_RS05270	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EQ029_RS05275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EQ029_RS05285	COG0656	L-ascorbic acid biosynthetic process
EQ029_RS05290	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQ029_RS05295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQ029_RS05305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EQ029_RS05330	COG3266	domain, Protein
EQ029_RS05330	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQ029_RS05330	COG4193	domain, Protein
EQ029_RS05345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQ029_RS05345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQ029_RS05350	COG0307	riboflavin synthase, alpha
EQ029_RS05355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQ029_RS05355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQ029_RS05360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EQ029_RS05365	COG0506	proline dehydrogenase activity
EQ029_RS05370	COG2267	carboxylic ester hydrolase activity
EQ029_RS05380	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EQ029_RS05385	COG1242	4 iron, 4 sulfur cluster binding
EQ029_RS05390	COG2814	Major facilitator Superfamily
EQ029_RS05395	COG0495	leucyl-tRNA aminoacylation
EQ029_RS05410	COG1196	nuclear chromosome segregation
EQ029_RS05410	COG4372	Transposase
EQ029_RS05410	COG1511	domain protein
EQ029_RS05420	COG2081	HI0933 family
EQ029_RS05425	COG2244	polysaccharide biosynthetic process
EQ029_RS05430	COG1187	pseudouridine synthase activity
EQ029_RS05440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQ029_RS05450	COG0510	thiamine kinase activity
EQ029_RS05455	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EQ029_RS05460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQ029_RS05470	COG1363	Peptidase, m42
EQ029_RS05475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQ029_RS05480	COG4848	Belongs to the UPF0354 family
EQ029_RS05485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQ029_RS05490	COG1674	ftsk spoiiie
EQ029_RS05495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EQ029_RS05500	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EQ029_RS05510	COG1605	Chorismate mutase
EQ029_RS05510	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EQ029_RS05515	COG1609	Transcriptional regulator
EQ029_RS05525	COG0454	-acetyltransferase
EQ029_RS05530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQ029_RS05535	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EQ029_RS05545	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EQ029_RS05555	COG0477	Major facilitator Superfamily
EQ029_RS05560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQ029_RS05565	COG0204	Acyl-transferase
EQ029_RS05570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ029_RS05570	COG1263	PTS System
EQ029_RS05580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EQ029_RS05590	COG1764	response to oxidative stress
EQ029_RS05595	COG0584	glycerophosphoryl diester phosphodiesterase
EQ029_RS05600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EQ029_RS05610	COG1956	GAF domain-containing protein
EQ029_RS05620	COG1104	cysteine desulfurase activity
EQ029_RS05625	COG0301	tRNA thio-modification
EQ029_RS05630	COG0730	response to heat
EQ029_RS05635	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EQ029_RS05640	COG0827	DNA restriction-modification system
EQ029_RS05645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EQ029_RS05655	COG0589	response to stress
EQ029_RS05660	COG0686	Belongs to the AlaDH PNT family
EQ029_RS05665	COG0006	proline dipeptidase activity
EQ029_RS05670	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EQ029_RS05680	COG4109	DRTGG domain
EQ029_RS05685	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EQ029_RS05690	COG0587	DNA-directed DNA polymerase activity
EQ029_RS05695	COG0281	malic enzyme
EQ029_RS05700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EQ029_RS05705	COG0825	malonyl-CoA metabolic process
EQ029_RS05710	COG0205	6-phosphofructokinase activity
EQ029_RS05715	COG0469	pyruvate kinase activity
EQ029_RS05730	COG1113	amino acid transport
EQ029_RS05735	COG0372	Belongs to the citrate synthase family
EQ029_RS05740	COG0538	isocitrate dehydrogenase activity
EQ029_RS05745	COG0745	RESPONSE REGULATOR receiver
EQ029_RS05750	COG5002	protein histidine kinase activity
EQ029_RS05755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQ029_RS05755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQ029_RS05765	COG0237	dephospho-CoA kinase activity
EQ029_RS05770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EQ029_RS05775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EQ029_RS05785	COG1484	DNA-dependent DNA replication
EQ029_RS05790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EQ029_RS05795	COG0833	amino acid
EQ029_RS05800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EQ029_RS05805	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EQ029_RS05810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EQ029_RS05815	COG4112	unkown
EQ029_RS05825	COG0544	peptidyl-prolyl cis-trans isomerase activity
EQ029_RS05830	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EQ029_RS05835	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EQ029_RS05840	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EQ029_RS05845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EQ029_RS05850	COG0181	hydroxymethylbilane synthase activity
EQ029_RS05865	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EQ029_RS05875	COG2818	Glycosylase
EQ029_RS05880	COG0525	valine-tRNA ligase activity
EQ029_RS05885	COG0285	dihydrofolate synthase activity
EQ029_RS05895	COG2003	Belongs to the UPF0758 family
EQ029_RS05920	COG1792	Involved in formation and maintenance of cell shape
EQ029_RS05930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EQ029_RS05935	COG2868	ribosomal protein
EQ029_RS05940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EQ029_RS05945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EQ029_RS05950	COG4492	Belongs to the UPF0735 family
EQ029_RS05955	COG0632	four-way junction helicase activity
EQ029_RS05960	COG2255	four-way junction helicase activity
EQ029_RS05965	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EQ029_RS05970	COG0343	queuine tRNA-ribosyltransferase activity
EQ029_RS05975	COG1862	Preprotein translocase
EQ029_RS05980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQ029_RS05980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQ029_RS05985	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EQ029_RS05985	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EQ029_RS05990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQ029_RS05995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EQ029_RS06000	COG1490	D-aminoacyl-tRNA deacylase activity
EQ029_RS06005	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQ029_RS06010	COG0124	histidyl-tRNA synthetase
EQ029_RS06015	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EQ029_RS06025	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EQ029_RS06030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EQ029_RS06035	COG1959	2 iron, 2 sulfur cluster binding
EQ029_RS06040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQ029_RS06045	COG1104	cysteine desulfurase activity
EQ029_RS06050	COG0482	sulfurtransferase activity
EQ029_RS06060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQ029_RS06065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EQ029_RS06070	COG4472	Bacterial protein of unknown function (DUF965)
EQ029_RS06075	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EQ029_RS06080	COG3906	Belongs to the UPF0473 family
EQ029_RS06090	COG0826	peptidase U32
EQ029_RS06095	COG0826	peptidase U32
EQ029_RS06100	COG0572	uridine kinase
EQ029_RS06105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EQ029_RS06110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EQ029_RS06115	COG1984	allophanate hydrolase subunit 2
EQ029_RS06120	COG0511	ligase activity, forming carbon-carbon bonds
EQ029_RS06125	COG0439	Biotin carboxylase
EQ029_RS06130	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EQ029_RS06135	COG1914	H( )-stimulated, divalent metal cation uptake system
EQ029_RS06140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EQ029_RS06145	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EQ029_RS06150	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EQ029_RS06155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EQ029_RS06160	COG1534	Rna-binding protein
EQ029_RS06165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EQ029_RS06170	COG1713	HD superfamily hydrolase involved in NAD metabolism
EQ029_RS06175	COG0799	negative regulation of ribosome biogenesis
EQ029_RS06180	COG2226	methyltransferase
EQ029_RS06185	COG1596	polysaccharide export
EQ029_RS06185	COG1555	photosystem II stabilization
EQ029_RS06190	COG2131	deaminase
EQ029_RS06195	COG0658	competence protein
EQ029_RS06195	COG2333	competence protein COMEC
EQ029_RS06200	COG1466	dna polymerase III delta subunit
EQ029_RS06205	COG0268	Binds directly to 16S ribosomal RNA
EQ029_RS06210	COG0481	GTPase activity
EQ029_RS06215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQ029_RS06220	COG1420	regulation of RNA biosynthetic process
EQ029_RS06225	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EQ029_RS06230	COG0443	Heat shock 70 kDa protein
EQ029_RS06235	COG0484	heat shock protein binding
EQ029_RS06240	COG2264	protein methyltransferase activity
EQ029_RS06245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EQ029_RS06250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EQ029_RS06260	COG1030	water channel activity
EQ029_RS06265	COG4864	UPF0365 protein
EQ029_RS06275	COG1702	phosphate starvation-inducible protein PhoH
EQ029_RS06280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EQ029_RS06285	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EQ029_RS06295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EQ029_RS06300	COG1381	Involved in DNA repair and RecF pathway recombination
EQ029_RS06305	COG0423	glycine-tRNA ligase activity
EQ029_RS06310	COG0517	IMP dehydrogenase activity
EQ029_RS06315	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EQ029_RS06325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EQ029_RS06330	COG2384	SAM-dependent methyltransferase
EQ029_RS06335	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EQ029_RS06340	COG0513	Belongs to the DEAD box helicase family
EQ029_RS06345	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EQ029_RS06350	COG1121	(ABC) transporter
EQ029_RS06355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQ029_RS06365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EQ029_RS06370	COG0768	penicillin binding
EQ029_RS06375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQ029_RS06380	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EQ029_RS06390	COG4483	Protein conserved in bacteria
EQ029_RS06395	COG1940	carbohydrate kinase activity
EQ029_RS06400	COG0011	TIGRFAM Protein of
EQ029_RS06405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQ029_RS06410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EQ029_RS06415	COG1459	type II secretion system
EQ029_RS06420	COG4537	Required for transformation and DNA binding
EQ029_RS06445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EQ029_RS06450	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EQ029_RS06455	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQ029_RS06460	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQ029_RS06465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQ029_RS06470	COG0095	Lipoate-protein ligase
EQ029_RS06485	COG0006	proline dipeptidase activity
EQ029_RS06490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EQ029_RS06495	COG0511	ligase activity, forming carbon-carbon bonds
EQ029_RS06500	COG0439	Biotin carboxylase
EQ029_RS06505	COG1302	Protein conserved in bacteria
EQ029_RS06510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQ029_RS06515	COG1570	exodeoxyribonuclease VII activity
EQ029_RS06520	COG1722	exodeoxyribonuclease VII activity
EQ029_RS06530	COG1438	arginine binding
EQ029_RS06535	COG0497	DNA recombination
EQ029_RS06540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQ029_RS06545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQ029_RS06550	COG0022	dehydrogenase e1 component
EQ029_RS06555	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQ029_RS06565	COG4129	membrane
EQ029_RS06575	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQ029_RS06585	COG1609	Transcriptional regulator
EQ029_RS06590	COG0366	Alpha amylase catalytic
EQ029_RS06605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EQ029_RS06610	COG1234	tRNA 3'-trailer cleavage
EQ029_RS06615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQ029_RS06620	COG0300	oxidoreductase activity
EQ029_RS06630	COG0667	Aldo Keto reductase
EQ029_RS06635	COG0494	nUDIX hydrolase
EQ029_RS06640	COG0735	belongs to the Fur family
EQ029_RS06645	COG4974	Belongs to the 'phage' integrase family
EQ029_RS06655	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EQ029_RS06660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EQ029_RS06665	COG1187	pseudouridine synthase activity
EQ029_RS06670	COG0745	RESPONSE REGULATOR receiver
EQ029_RS06685	COG1141	Ferredoxin
EQ029_RS06695	COG0514	ATP-dependent DNA helicase (RecQ)
EQ029_RS06700	COG1388	LysM domain
EQ029_RS06705	COG0492	ferredoxin-NADP+ reductase activity
EQ029_RS06715	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EQ029_RS06720	COG0539	negative regulation of cytoplasmic translation
EQ029_RS06725	COG1160	GTP binding
EQ029_RS06730	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EQ029_RS06745	COG2226	methyltransferase
EQ029_RS06750	COG0142	geranyltranstransferase activity
EQ029_RS06755	COG0105	UTP biosynthetic process
EQ029_RS06760	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EQ029_RS06765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EQ029_RS06770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EQ029_RS06775	COG0457	Tetratricopeptide repeat
EQ029_RS06780	COG5582	Belongs to the UPF0302 family
EQ029_RS06785	COG4347	Protein of unknown function (DUF1405)
EQ029_RS06790	COG2738	Putative neutral zinc metallopeptidase
EQ029_RS06795	COG1694	Mazg nucleotide pyrophosphohydrolase
EQ029_RS06800	COG0438	transferase activity, transferring glycosyl groups
EQ029_RS06805	COG0617	tRNA 3'-terminal CCA addition
EQ029_RS06815	COG1199	ATP-dependent helicase activity
EQ029_RS06815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQ029_RS06820	COG0017	Asparaginyl-tRNA synthetase
EQ029_RS06825	COG3935	DnaD domain protein
EQ029_RS06830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EQ029_RS06840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQ029_RS06840	COG4499	WXG100 protein secretion system (Wss), protein YukC
EQ029_RS06845	COG3331	DNA recombination
EQ029_RS06855	COG4474	Belongs to the UPF0398 family
EQ029_RS06860	COG3599	regulation of cell shape
EQ029_RS06870	COG0116	Belongs to the methyltransferase superfamily
EQ029_RS06880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EQ029_RS06885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQ029_RS06905	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EQ029_RS06915	COG1413	lyase activity
EQ029_RS06920	COG1413	lyase activity
EQ029_RS06930	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EQ029_RS06950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQ029_RS06955	COG2190	(PTS) system
EQ029_RS06960	COG4479	Belongs to the UPF0346 family
EQ029_RS06965	COG0793	Belongs to the peptidase S41A family
EQ029_RS06975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQ029_RS06980	COG0671	phosphoesterase, PA-phosphatase related
EQ029_RS06985	COG0745	RESPONSE REGULATOR receiver
EQ029_RS06990	COG5002	protein histidine kinase activity
EQ029_RS06995	COG0567	Dehydrogenase, E1 component
EQ029_RS07000	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQ029_RS07020	COG0714	Associated with various cellular activities
EQ029_RS07025	COG4548	von Willebrand factor, type A
EQ029_RS07030	COG1114	Component of the transport system for branched-chain amino acids
EQ029_RS07035	COG3853	Toxic anion resistance protein (TelA)
EQ029_RS07045	COG1254	Belongs to the acylphosphatase family
EQ029_RS07055	COG1278	Cold shock
EQ029_RS07075	COG1473	amidohydrolase
EQ029_RS07080	COG2171	N-acyltransferase activity
EQ029_RS07085	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EQ029_RS07090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQ029_RS07095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EQ029_RS07105	COG0488	(ABC) transporter
EQ029_RS07110	COG2996	Protein conserved in bacteria
EQ029_RS07115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EQ029_RS07120	COG0573	inorganic phosphate transmembrane transporter activity
EQ029_RS07125	COG0581	inorganic phosphate transmembrane transporter activity
EQ029_RS07130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQ029_RS07135	COG0704	Plays a role in the regulation of phosphate uptake
EQ029_RS07140	COG1164	Oligoendopeptidase f
EQ029_RS07150	COG4607	ABC-type enterochelin transport system periplasmic component
EQ029_RS07155	COG0561	phosphatase activity
EQ029_RS07160	COG2348	transferase activity, transferring amino-acyl groups
EQ029_RS07165	COG2348	transferase activity, transferring amino-acyl groups
EQ029_RS07175	COG0159	tryptophan synthase activity
EQ029_RS07185	COG0135	phosphoribosylanthranilate isomerase activity
EQ029_RS07190	COG0134	indole-3-glycerol-phosphate synthase activity
EQ029_RS07195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQ029_RS07200	COG0512	Glutamine amidotransferase of anthranilate synthase
EQ029_RS07205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EQ029_RS07210	COG1363	Peptidase, m42
EQ029_RS07215	COG0287	Prephenate dehydrogenase
EQ029_RS07220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQ029_RS07225	COG1942	4-Oxalocrotonate Tautomerase
EQ029_RS07240	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EQ029_RS07240	COG0392	lysyltransferase activity
EQ029_RS07245	COG0628	permease
EQ029_RS07250	COG3711	transcriptional antiterminator
EQ029_RS07255	COG1115	amino acid carrier protein
EQ029_RS07260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQ029_RS07265	COG0187	DNA topoisomerase II activity
EQ029_RS07270	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EQ029_RS07275	COG4841	protein insertion into membrane
EQ029_RS07280	COG0824	Thioesterase
EQ029_RS07285	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EQ029_RS07290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQ029_RS07295	COG1970	mechanosensitive ion channel activity
EQ029_RS07300	COG0419	ATPase involved in DNA repair
EQ029_RS07305	COG0420	3'-5' exonuclease activity
EQ029_RS07310	COG4846	Membrane protein involved in cytochrome C biogenesis
EQ029_RS07325	COG4224	UPF0291 protein
EQ029_RS07335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQ029_RS07340	COG2340	Cysteine-rich secretory protein family
EQ029_RS07345	COG0516	GMP reductase activity
EQ029_RS07350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQ029_RS07360	COG0753	catalase activity
EQ029_RS07365	COG0833	amino acid
EQ029_RS07380	COG0083	homoserine kinase activity
EQ029_RS07385	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EQ029_RS07390	COG0460	homoserine dehydrogenase
EQ029_RS07395	COG0527	aspartate kinase activity
EQ029_RS07425	COG2197	response regulator
EQ029_RS07430	COG4585	Histidine kinase
EQ029_RS07440	COG1131	(ABC) transporter
EQ029_RS07445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQ029_RS07495	COG0789	Transcriptional regulator
EQ029_RS07500	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EQ029_RS07505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EQ029_RS07510	COG0386	Belongs to the glutathione peroxidase family
EQ029_RS07515	COG1923	regulation of RNA biosynthetic process
EQ029_RS07520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EQ029_RS07530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EQ029_RS07535	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EQ029_RS07540	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQ029_RS07550	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EQ029_RS07555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EQ029_RS07565	COG4550	Control of competence regulator ComK, YlbF/YmcA
EQ029_RS07570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EQ029_RS07580	COG4195	phage-related replication protein
EQ029_RS07585	COG1013	pyruvate-flavodoxin oxidoreductase activity
EQ029_RS07590	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EQ029_RS07590	COG0674	pyruvate-flavodoxin oxidoreductase activity
EQ029_RS07595	COG1692	metallophosphoesterase
EQ029_RS07605	COG1418	mRNA catabolic process
EQ029_RS07610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EQ029_RS07615	COG1546	Belongs to the CinA family
EQ029_RS07615	COG1058	Belongs to the CinA family
EQ029_RS07635	COG0300	oxidoreductase activity
EQ029_RS07640	COG0612	Peptidase, M16
EQ029_RS07645	COG0612	Peptidase, M16
EQ029_RS07650	COG2188	Transcriptional regulator
EQ029_RS07655	COG1674	ftsk spoiiie
EQ029_RS07660	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EQ029_RS07665	COG1185	polyribonucleotide nucleotidyltransferase activity
EQ029_RS07670	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EQ029_RS07675	COG0196	riboflavin kinase activity
EQ029_RS07680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EQ029_RS07685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EQ029_RS07690	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EQ029_RS07695	COG1358	cellular component organization or biogenesis
EQ029_RS07700	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EQ029_RS07705	COG0195	Participates in both transcription termination and antitermination
EQ029_RS07710	COG0779	Required for maturation of 30S ribosomal subunits
EQ029_RS07715	COG2176	DNA-directed DNA polymerase activity
EQ029_RS07720	COG0442	prolyl-tRNA aminoacylation
EQ029_RS07730	COG4589	Belongs to the CDS family
EQ029_RS07735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EQ029_RS07740	COG0233	cytoplasmic translational termination
EQ029_RS07745	COG0528	UMP kinase activity
EQ029_RS07750	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EQ029_RS07755	COG0052	Belongs to the universal ribosomal protein uS2 family
EQ029_RS07760	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EQ029_RS07765	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EQ029_RS07770	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EQ029_RS07775	COG4974	Belongs to the 'phage' integrase family
EQ029_RS07780	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EQ029_RS07785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQ029_RS07790	COG0758	DNA mediated transformation
EQ029_RS07800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EQ029_RS07805	COG0045	succinate-CoA ligase (ADP-forming) activity
EQ029_RS07810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQ029_RS07820	COG4485	Bacterial membrane protein, YfhO
EQ029_RS07830	COG0335	large ribosomal subunit rRNA binding
EQ029_RS07835	COG0336	Belongs to the RNA methyltransferase TrmD family
EQ029_RS07840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EQ029_RS07845	COG0228	four-way junction DNA binding
EQ029_RS07850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EQ029_RS07855	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EQ029_RS07860	COG0552	protein localization to endoplasmic reticulum
EQ029_RS07865	COG1196	nuclear chromosome segregation
EQ029_RS07870	COG0571	ribonuclease III activity
EQ029_RS07875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQ029_RS07880	COG1028	Short-chain dehydrogenase reductase Sdr
EQ029_RS07890	COG0416	fatty acid biosynthetic process
EQ029_RS07895	COG1349	DNA-binding transcription factor activity
EQ029_RS07910	COG1461	Dihydroxyacetone kinase
EQ029_RS07915	COG1302	Protein conserved in bacteria
EQ029_RS07920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EQ029_RS07925	COG1564	THIamine pyrophosphokinase
EQ029_RS07930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQ029_RS07935	COG1162	GTPase activity
EQ029_RS07945	COG0631	protein serine/threonine phosphatase activity
EQ029_RS07950	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EQ029_RS07955	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQ029_RS07955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EQ029_RS07960	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EQ029_RS07975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EQ029_RS07980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EQ029_RS07985	COG1758	RNA polymerase activity
EQ029_RS07990	COG0194	GDP metabolic process
EQ029_RS08010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EQ029_RS08015	COG0284	orotidine-5'-phosphate decarboxylase activity
EQ029_RS08020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQ029_RS08025	COG0505	Belongs to the CarA family
EQ029_RS08035	COG0540	Belongs to the ATCase OTCase family
EQ029_RS08040	COG2233	PERMEase
EQ029_RS08045	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EQ029_RS08050	COG0564	pseudouridine synthase activity
EQ029_RS08055	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EQ029_RS08060	COG1388	LysM domain
EQ029_RS08060	COG3942	CHAP domain
EQ029_RS08070	COG0702	epimerase
EQ029_RS08075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EQ029_RS08080	COG3599	regulation of cell shape
EQ029_RS08090	COG0762	integral membrane protein
EQ029_RS08095	COG1799	cell septum assembly
EQ029_RS08100	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EQ029_RS08105	COG1496	oxidoreductase activity
EQ029_RS08110	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EQ029_RS08115	COG0849	cell division
EQ029_RS08120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EQ029_RS08125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQ029_RS08130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQ029_RS08135	COG0768	penicillin binding
EQ029_RS08140	COG4839	cell division protein FtsL
EQ029_RS08145	COG0275	rRNA processing
EQ029_RS08150	COG2001	Belongs to the MraZ family
EQ029_RS08155	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EQ029_RS08160	COG0454	-acetyltransferase
EQ029_RS08165	COG1011	Hydrolase
EQ029_RS08285	COG0740	serine-type endopeptidase activity
EQ029_RS08370	COG0756	dUTP diphosphatase activity
EQ029_RS08435	COG3620	sequence-specific DNA binding
EQ029_RS08460	COG0582	viral genome integration into host DNA
EQ029_RS08470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EQ029_RS08475	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EQ029_RS08480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EQ029_RS08485	COG1053	succinate dehydrogenase
EQ029_RS08490	COG2009	succinate dehydrogenase
EQ029_RS08495	COG0322	excinuclease ABC activity
EQ029_RS08500	COG3118	belongs to the thioredoxin family
EQ029_RS08505	COG1193	negative regulation of DNA recombination
EQ029_RS08510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EQ029_RS08510	COG1796	DNA polymerase
EQ029_RS08520	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EQ029_RS08525	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQ029_RS08530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQ029_RS08530	COG0072	phenylalanine-tRNA ligase activity
EQ029_RS08535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EQ029_RS08540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQ029_RS08545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EQ029_RS08560	COG1323	Belongs to the UPF0348 family
EQ029_RS08565	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EQ029_RS08570	COG0742	ribosomal rna small subunit methyltransferase
EQ029_RS08580	COG4471	UPF0298 protein
EQ029_RS08590	COG3679	Belongs to the UPF0342 family
EQ029_RS08595	COG2340	Cysteine-rich secretory protein family
EQ029_RS08605	COG0109	protoheme IX farnesyltransferase activity
EQ029_RS08610	COG1612	heme a metabolic process
EQ029_RS08620	COG0772	Belongs to the SEDS family
EQ029_RS08625	COG4838	Belongs to the UPF0358 family
EQ029_RS08630	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EQ029_RS08635	COG4896	Protein conserved in bacteria
EQ029_RS08640	COG1217	gtp-binding protein TYPA
EQ029_RS08650	COG0483	inositol monophosphate 1-phosphatase activity
EQ029_RS08655	COG4493	Belongs to the UPF0637 family
EQ029_RS08660	COG1914	H( )-stimulated, divalent metal cation uptake system
EQ029_RS08685	COG1177	transmembrane transport
EQ029_RS08690	COG1176	ABC-type spermidine putrescine transport system, permease component I
EQ029_RS08695	COG3842	ATPase activity
EQ029_RS08700	COG1396	sequence-specific DNA binding
EQ029_RS08700	COG3800	Transcriptional regulator
EQ029_RS08705	COG4476	Belongs to the UPF0223 family
EQ029_RS08735	COG0242	peptide deformylase activity
EQ029_RS08740	COG5503	Protein of unknown function (DUF1447)
EQ029_RS08745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EQ029_RS08755	COG2832	Protein of unknown function (DUF454)
EQ029_RS08760	COG0569	domain protein
EQ029_RS08765	COG1294	oxidase, subunit
EQ029_RS08770	COG1271	oxidase subunit
EQ029_RS08790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EQ029_RS08805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EQ029_RS08825	COG1122	ATPase activity
EQ029_RS08830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EQ029_RS08835	COG0151	Belongs to the GarS family
EQ029_RS08840	COG0138	bifunctional purine biosynthesis protein purh
EQ029_RS08850	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EQ029_RS08860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQ029_RS08865	COG0047	phosphoribosylformylglycinamidine synthase activity
EQ029_RS08870	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQ029_RS08875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EQ029_RS08880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EQ029_RS08885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EQ029_RS08890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EQ029_RS08915	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EQ029_RS08920	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EQ029_RS08925	COG1845	cytochrome c oxidase, subunit III
EQ029_RS08930	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EQ029_RS08940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQ029_RS08945	COG1316	TRANSCRIPTIONal
EQ029_RS08975	COG3594	Acyltransferase
EQ029_RS08980	COG0436	Aminotransferase
EQ029_RS08985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EQ029_RS08990	COG0596	Alpha beta hydrolase
EQ029_RS08995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EQ029_RS09000	COG1169	isochorismate synthase
EQ029_RS09005	COG1575	Belongs to the MenA family. Type 1 subfamily
EQ029_RS09060	COG4873	Protein conserved in bacteria
EQ029_RS09080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQ029_RS09085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQ029_RS09090	COG0861	Integral membrane protein TerC family
EQ029_RS09095	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EQ029_RS09105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EQ029_RS09110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQ029_RS09115	COG2814	Major facilitator Superfamily
EQ029_RS09120	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EQ029_RS09125	COG2382	esterase
EQ029_RS09130	COG0628	permease
EQ029_RS09140	COG0475	glutathione-regulated potassium exporter activity
EQ029_RS09140	COG0569	domain protein
EQ029_RS09145	COG2239	Acts as a magnesium transporter
EQ029_RS09150	COG0564	pseudouridine synthase activity
EQ029_RS09155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EQ029_RS09160	COG2357	RelA SpoT domain protein
EQ029_RS09170	COG4116	CYTH
EQ029_RS09175	COG2346	COG2346, Truncated hemoglobins
EQ029_RS09180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EQ029_RS09185	COG1164	Oligoendopeptidase f
EQ029_RS09195	COG4862	establishment of competence for transformation
EQ029_RS09200	COG1393	Belongs to the ArsC family
EQ029_RS09205	COG0180	Tryptophanyl-tRNA synthetase
EQ029_RS09225	COG4166	transmembrane transport
EQ029_RS09230	COG4608	Belongs to the ABC transporter superfamily
EQ029_RS09235	COG0444	Belongs to the ABC transporter superfamily
EQ029_RS09240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQ029_RS09245	COG0601	transmembrane transport
EQ029_RS09260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQ029_RS09270	COG0542	response to heat
EQ029_RS09285	COG0561	phosphatase activity
EQ029_RS09290	COG0446	pyridine nucleotide-disulphide oxidoreductase
EQ029_RS09300	COG0179	Fumarylacetoacetate (FAA) hydrolase
EQ029_RS09305	COG1074	ATP-dependent DNA helicase activity
EQ029_RS09310	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EQ029_RS09325	COG0398	Pfam SNARE associated Golgi protein
EQ029_RS09330	COG0166	Belongs to the GPI family
EQ029_RS09335	COG0137	argininosuccinate synthase activity
EQ029_RS09340	COG0165	Argininosuccinate lyase
EQ029_RS09345	COG0584	glycerophosphoryl diester phosphodiesterase
EQ029_RS09360	COG1902	pentaerythritol trinitrate reductase activity
EQ029_RS09370	COG1098	S1 RNA binding domain
EQ029_RS09375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EQ029_RS09385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQ029_RS09385	COG2111	Na H antiporter
EQ029_RS09390	COG2111	Na H antiporter
EQ029_RS09395	COG1006	Multisubunit Na H antiporter MnhC subunit
EQ029_RS09400	COG0651	ATP synthesis coupled electron transport
EQ029_RS09405	COG1863	multisubunit Na H antiporter MnhE subunit
EQ029_RS09410	COG2212	antiporter activity
EQ029_RS09415	COG1320	monovalent cation:proton antiporter activity
EQ029_RS09425	COG2050	protein possibly involved in aromatic compounds catabolism
EQ029_RS09430	COG2056	Na+-H+ antiporter family
EQ029_RS09435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EQ029_RS09440	COG1252	NADH dehydrogenase
EQ029_RS09445	COG0316	Belongs to the HesB IscA family
EQ029_RS09450	COG4844	belongs to the
EQ029_RS09455	COG1252	NADH dehydrogenase
EQ029_RS09460	COG4837	Protein of unknown function (DUF1462)
EQ029_RS09465	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EQ029_RS09470	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EQ029_RS09475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQ029_RS09480	COG1696	Membrane protein involved in D-alanine export
EQ029_RS09485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQ029_RS09500	COG0647	UMP catabolic process
EQ029_RS09505	COG2445	Protein of unknown function DUF86
EQ029_RS09515	COG4470	Protein conserved in bacteria
EQ029_RS09520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EQ029_RS09525	COG0737	Belongs to the 5'-nucleotidase family
EQ029_RS09530	COG0730	response to heat
EQ029_RS09535	COG1801	Protein of unknown function DUF72
EQ029_RS09540	COG2070	2-Nitropropane dioxygenase
EQ029_RS09550	COG0719	Fe-S assembly protein
EQ029_RS09555	COG0822	iron-sulfur transferase activity
EQ029_RS09565	COG0719	Fe-S assembly protein
EQ029_RS09570	COG0396	ATPase activity
EQ029_RS09585	COG3237	CsbD-like
EQ029_RS09590	COG1464	Belongs to the NlpA lipoprotein family
EQ029_RS09595	COG2011	ABC-type metal ion transport system permease component
EQ029_RS09600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQ029_RS09610	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQ029_RS09615	COG0509	glycine decarboxylation via glycine cleavage system
EQ029_RS09620	COG1393	Belongs to the ArsC family
EQ029_RS09625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQ029_RS09635	COG0710	3-dehydroquinate dehydratase activity
EQ029_RS09640	COG1764	response to oxidative stress
EQ029_RS09650	COG1279	arginine transmembrane transporter activity
EQ029_RS09655	COG0406	alpha-ribazole phosphatase activity
EQ029_RS09695	COG0456	acetyltransferase
EQ029_RS09700	COG4195	phage-related replication protein
EQ029_RS09730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EQ029_RS09735	COG0557	exoribonuclease II activity
EQ029_RS09740	COG1647	Serine aminopeptidase, S33
EQ029_RS09745	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EQ029_RS09755	COG0148	phosphopyruvate hydratase activity
EQ029_RS09760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EQ029_RS09765	COG0149	triose-phosphate isomerase activity
EQ029_RS09770	COG0126	phosphoglycerate kinase activity
EQ029_RS09800	COG1090	epimerase
EQ029_RS09810	COG0740	serine-type endopeptidase activity
EQ029_RS09820	COG1481	regulation of sporulation
EQ029_RS09825	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EQ029_RS09830	COG1660	Displays ATPase and GTPase activities
EQ029_RS09835	COG0492	ferredoxin-NADP+ reductase activity
EQ029_RS09850	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EQ029_RS09855	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EQ029_RS09860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQ029_RS09865	COG0556	nucleotide-excision repair
EQ029_RS09880	COG0300	oxidoreductase activity
EQ029_RS09885	COG1388	LysM domain
EQ029_RS09885	COG3942	CHAP domain
EQ029_RS09895	COG0653	protein targeting
EQ029_RS09900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EQ029_RS09905	COG1040	competence protein
EQ029_RS09920	COG1739	Uncharacterized protein family UPF0029
EQ029_RS09925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQ029_RS09930	COG2199	diguanylate cyclase activity
EQ029_RS09945	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQ029_RS09950	COG1929	Belongs to the glycerate kinase type-1 family
EQ029_RS09970	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EQ029_RS09980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQ029_RS09985	COG4607	ABC-type enterochelin transport system periplasmic component
EQ029_RS09990	COG4604	ABC transporter, ATP-binding protein
EQ029_RS09995	COG4605	iron ion homeostasis
EQ029_RS10000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ029_RS10005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQ029_RS10010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQ029_RS10015	COG1780	Probably involved in ribonucleotide reductase function
EQ029_RS10025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EQ029_RS10030	COG3104	oligopeptide transport
EQ029_RS10035	COG1597	lipid kinase activity
EQ029_RS10045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EQ029_RS10050	COG3104	oligopeptide transport
EQ029_RS10055	COG1174	glycine betaine transport
EQ029_RS10065	COG0514	ATP-dependent DNA helicase (RecQ)
EQ029_RS10070	COG0488	(ABC) transporter
EQ029_RS10080	COG1368	sulfuric ester hydrolase activity
EQ029_RS10085	COG1984	allophanate hydrolase subunit 2
EQ029_RS10090	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EQ029_RS10110	COG0512	Glutamine amidotransferase of anthranilate synthase
EQ029_RS10110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQ029_RS10115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EQ029_RS10120	COG0720	synthase
EQ029_RS10125	COG0602	queuosine metabolic process
EQ029_RS10135	COG0463	Glycosyl transferase, family 2
EQ029_RS10145	COG0656	L-ascorbic acid biosynthetic process
EQ029_RS10150	COG1253	flavin adenine dinucleotide binding
EQ029_RS10160	COG1105	Belongs to the carbohydrate kinase PfkB family
EQ029_RS10165	COG1349	DNA-binding transcription factor activity
EQ029_RS10170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EQ029_RS10200	COG0415	Belongs to the DNA photolyase family
EQ029_RS10205	COG0471	metal ion transport
EQ029_RS10215	COG0523	cobalamin synthesis protein
EQ029_RS10230	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EQ029_RS10235	COG4988	ABC transporter
EQ029_RS10240	COG1968	undecaprenyl-diphosphatase activity
EQ029_RS10250	COG1671	Belongs to the UPF0178 family
EQ029_RS10255	COG1611	Belongs to the LOG family
EQ029_RS10260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQ029_RS10275	COG0456	acetyltransferase
EQ029_RS10285	COG2839	Protein conserved in bacteria
EQ029_RS10295	COG0583	DNA-binding transcription factor activity
EQ029_RS10305	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQ029_RS10315	COG0217	transcriptional regulatory protein
EQ029_RS10335	COG1388	LysM domain
EQ029_RS10335	COG3942	CHAP domain
EQ029_RS10340	COG0306	phosphate transporter
EQ029_RS10345	COG1392	Phosphate transport regulator
EQ029_RS10350	COG0577	efflux transmembrane transporter activity
EQ029_RS10355	COG1136	(ABC) transporter
EQ029_RS10360	COG2205	protein histidine kinase activity
EQ029_RS10365	COG0745	RESPONSE REGULATOR receiver
EQ029_RS10370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQ029_RS10380	COG0657	acetylesterase activity
EQ029_RS10385	COG3949	Membrane
EQ029_RS10395	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EQ029_RS10405	COG2376	Dihydroxyacetone kinase
EQ029_RS10410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ029_RS10415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ029_RS10420	COG1120	ATPase activity
EQ029_RS10425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQ029_RS10430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQ029_RS10435	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQ029_RS10435	COG0463	Glycosyl transferase, family 2
EQ029_RS10445	COG1132	(ABC) transporter
EQ029_RS10450	COG1686	Belongs to the peptidase S11 family
EQ029_RS10455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EQ029_RS10465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQ029_RS10470	COG1682	transport, permease protein
EQ029_RS10475	COG1134	teichoic acid transport
EQ029_RS10480	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EQ029_RS10490	COG1321	iron dependent repressor
EQ029_RS10515	COG1320	monovalent cation:proton antiporter activity
EQ029_RS10520	COG2212	antiporter activity
EQ029_RS10525	COG1863	multisubunit Na H antiporter MnhE subunit
EQ029_RS10530	COG0651	ATP synthesis coupled electron transport
EQ029_RS10535	COG1006	Multisubunit Na H antiporter MnhC subunit
EQ029_RS10540	COG2111	Na H antiporter
EQ029_RS10545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQ029_RS10545	COG2111	Na H antiporter
EQ029_RS10605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQ029_RS10610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQ029_RS10625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EQ029_RS10630	COG0018	arginyl-trna synthetase
EQ029_RS10670	COG1078	dGTPase activity
EQ029_RS10680	COG0655	NAD(P)H dehydrogenase (quinone) activity
EQ029_RS10685	COG0667	Aldo Keto reductase
EQ029_RS10695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQ029_RS10700	COG1278	Cold shock
EQ029_RS10705	COG4844	belongs to the
EQ029_RS10725	COG0095	Lipoate-protein ligase
EQ029_RS10735	COG3253	May function as heme-dependent peroxidase
EQ029_RS10740	COG2966	Psort location CytoplasmicMembrane, score
EQ029_RS10760	COG2363	Small membrane protein
EQ029_RS10770	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EQ029_RS10780	COG0477	Major facilitator Superfamily
EQ029_RS10795	COG0183	Belongs to the thiolase family
EQ029_RS10800	COG0318	PFAM AMP-dependent synthetase and ligase
EQ029_RS10805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EQ029_RS10810	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EQ029_RS10820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQ029_RS10825	COG1469	GTP cyclohydrolase I activity
EQ029_RS10865	COG0431	NADPH-dependent FMN reductase
EQ029_RS10870	COG0561	phosphatase activity
EQ029_RS10880	COG1428	Deoxynucleoside kinase
EQ029_RS10885	COG1428	Deoxynucleoside kinase
EQ029_RS10890	COG0546	phosphoglycolate phosphatase activity
EQ029_RS10930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQ029_RS10935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQ029_RS10940	COG0737	Belongs to the 5'-nucleotidase family
EQ029_RS10965	COG1473	amidohydrolase
EQ029_RS10970	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EQ029_RS10975	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EQ029_RS10985	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EQ029_RS10995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EQ029_RS11000	COG0085	RNA polymerase activity
EQ029_RS11005	COG2813	Specifically methylates the guanine in position
EQ029_RS11010	COG0222	ribosome binding
EQ029_RS11015	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EQ029_RS11025	COG0081	regulation of translation
EQ029_RS11030	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EQ029_RS11035	COG0250	Participates in transcription elongation, termination and antitermination
EQ029_RS11040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EQ029_RS11045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQ029_RS11055	COG3688	RNA-binding protein containing a PIN domain
EQ029_RS11060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQ029_RS11065	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EQ029_RS11070	COG0215	cysteine-tRNA ligase activity
EQ029_RS11075	COG1045	serine acetyltransferase
EQ029_RS11080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EQ029_RS11085	COG4956	integral membrane protein (PIN domain superfamily)
EQ029_RS11090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EQ029_RS11095	COG0542	response to heat
EQ029_RS11100	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EQ029_RS11105	COG3880	PFAM UvrB UvrC protein
EQ029_RS11110	COG4463	regulation of RNA biosynthetic process
EQ029_RS11115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQ029_RS11120	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EQ029_RS11125	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EQ029_RS11130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQ029_RS11135	COG2259	Doxx family
EQ029_RS11220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EQ029_RS11225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EQ029_RS11240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQ029_RS11245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EQ029_RS11250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EQ029_RS11260	COG0037	tRNA processing
EQ029_RS11265	COG1098	S1 RNA binding domain
EQ029_RS11275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EQ029_RS11280	COG3956	TIGRFAM MazG family protein
EQ029_RS11285	COG2244	polysaccharide biosynthetic process
EQ029_RS11290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EQ029_RS11295	COG0193	aminoacyl-tRNA hydrolase activity
EQ029_RS11300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EQ029_RS11305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EQ029_RS11310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EQ029_RS11315	COG2088	sporulation resulting in formation of a cellular spore
EQ029_RS11320	COG0251	oxidation-reduction process
EQ029_RS11325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQ029_RS11330	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EQ029_RS11335	COG4466	Protein conserved in bacteria
EQ029_RS11340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EQ029_RS11345	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQ029_RS11350	COG0084	hydrolase, TatD family'
EQ029_RS11355	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQ029_RS11355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQ029_RS11360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EQ029_RS11365	COG2827	Endonuclease containing a URI domain
EQ029_RS11370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EQ029_RS11375	COG4467	Involved in initiation control of chromosome replication
EQ029_RS11380	COG1774	PSP1 C-terminal conserved region
EQ029_RS11385	COG0470	DNA polymerase III
EQ029_RS11390	COG3870	Protein conserved in bacteria
EQ029_RS11395	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EQ029_RS11400	COG1982	Orn Lys Arg decarboxylase major
EQ029_RS11425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EQ029_RS11435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EQ029_RS11450	COG2188	Transcriptional regulator
EQ029_RS11455	COG0366	Alpha amylase catalytic
EQ029_RS11460	COG1263	PTS System
EQ029_RS11460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQ029_RS11470	COG0493	'glutamate synthase
EQ029_RS11475	COG0070	glutamate synthase
EQ029_RS11475	COG0069	glutamate synthase activity
EQ029_RS11475	COG0067	glutamate synthase
EQ029_RS11510	COG1388	LysM domain
EQ029_RS11510	COG3942	CHAP domain
EQ029_RS11515	COG0626	cystathionine gamma-synthase activity
EQ029_RS11520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQ029_RS11535	COG0733	neurotransmitter:sodium symporter activity
EQ029_RS11550	COG1647	Serine aminopeptidase, S33
EQ029_RS11560	COG0671	phosphoesterase, PA-phosphatase related
EQ029_RS11570	COG5609	conserved protein (DUF2294)
EQ029_RS11575	COG3002	Belongs to the UPF0753 family
EQ029_RS11580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQ029_RS11590	COG3759	membrane
EQ029_RS11605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQ029_RS11615	COG3728	DNA packaging
EQ029_RS11615	COG5484	DNA packaging
EQ029_RS11690	COG0582	viral genome integration into host DNA
EQ029_RS11695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EQ029_RS11695	COG0519	Catalyzes the synthesis of GMP from XMP
EQ029_RS11700	COG0516	GMP reductase activity
EQ029_RS11700	COG0517	IMP dehydrogenase activity
EQ029_RS11705	COG2233	PERMEase
EQ029_RS11710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQ029_RS11730	COG1823	symporter activity
EQ029_RS11735	COG0778	Nitroreductase
EQ029_RS11745	COG0450	alkyl hydroperoxide reductase
EQ029_RS11750	COG3634	alkyl hydroperoxide reductase activity
EQ029_RS11760	COG0406	alpha-ribazole phosphatase activity
EQ029_RS11765	COG1280	lysine exporter protein (LysE YggA)
EQ029_RS11830	COG3226	Transcriptional regulator
EQ029_RS11840	COG1012	belongs to the aldehyde dehydrogenase family
EQ029_RS11850	COG1902	pentaerythritol trinitrate reductase activity
EQ029_RS11865	COG1131	(ABC) transporter
EQ029_RS11895	COG0579	oxidoreductase
EQ029_RS11900	COG1733	regulation of RNA biosynthetic process
EQ029_RS11905	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EQ029_RS11910	COG0693	protein deglycase activity
EQ029_RS11955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EQ029_RS11965	COG0360	Binds together with S18 to 16S ribosomal RNA
EQ029_RS11980	COG0012	GTP binding
EQ029_RS11985	COG4481	Protein conserved in bacteria
EQ029_RS11990	COG0668	transmembrane transport
EQ029_RS11995	COG1475	DNA binding
EQ029_RS12000	COG0626	cystathionine gamma-synthase activity
EQ029_RS12005	COG0626	cystathionine gamma-synthase activity
EQ029_RS12010	COG0646	methionine synthase
EQ029_RS12010	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EQ029_RS12015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQ029_RS12030	COG0488	(ABC) transporter
EQ029_RS12040	COG0346	lactoylglutathione lyase activity
EQ029_RS12050	COG3250	beta-galactosidase activity
EQ029_RS12055	COG1028	Short-chain dehydrogenase reductase Sdr
EQ029_RS12060	COG1312	Catalyzes the dehydration of D-mannonate
EQ029_RS12065	COG1904	glucuronate isomerase
EQ029_RS12070	COG2211	Major facilitator Superfamily
EQ029_RS12075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQ029_RS12100	COG3448	diguanylate cyclase activity
EQ029_RS12100	COG4175	Glycine betaine
EQ029_RS12115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQ029_RS12140	COG1136	(ABC) transporter
EQ029_RS12145	COG0577	efflux transmembrane transporter activity
EQ029_RS12185	COG0357	Ribosomal RNA small subunit methyltransferase G
EQ029_RS12190	COG0445	tRNA wobble uridine modification
EQ029_RS12195	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EQ029_RS12200	COG0594	ribonuclease P activity
EQ029_RS12250	COG0693	protein deglycase activity
EQ029_RS12320	COG2855	membrane
EQ029_RS12325	COG0583	DNA-binding transcription factor activity
EQ029_RS12350	COG2153	protein acetylation
EQ029_RS12380	COG0659	secondary active sulfate transmembrane transporter activity
EQ029_RS12385	COG0589	response to stress
EQ029_RS12420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EQ029_RS12435	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EQ029_RS12445	COG1733	regulation of RNA biosynthetic process
EQ029_RS12460	COG0640	Transcriptional regulator
EQ029_RS12465	COG2217	Heavy metal translocating P-type atpase