locus-tag	class	description
EGX85_RS00075	COG1230	cation diffusion facilitator family transporter
EGX85_RS00110	COG2211	Major facilitator Superfamily
EGX85_RS00135	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGX85_RS00140	COG3775	system Galactitol-specific IIC component
EGX85_RS00145	COG1609	Transcriptional regulator
EGX85_RS00150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX85_RS00200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGX85_RS00205	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGX85_RS00210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX85_RS00215	COG0095	Lipoate-protein ligase
EGX85_RS00230	COG0006	proline dipeptidase activity
EGX85_RS00235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EGX85_RS00240	COG0511	ligase activity, forming carbon-carbon bonds
EGX85_RS00245	COG0439	Biotin carboxylase
EGX85_RS00250	COG1302	Protein conserved in bacteria
EGX85_RS00255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGX85_RS00260	COG1570	exodeoxyribonuclease VII activity
EGX85_RS00265	COG1722	exodeoxyribonuclease VII activity
EGX85_RS00275	COG1438	arginine binding
EGX85_RS00280	COG0497	DNA recombination
EGX85_RS00285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX85_RS00290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGX85_RS00295	COG0022	dehydrogenase e1 component
EGX85_RS00300	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX85_RS00310	COG4129	membrane
EGX85_RS00320	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX85_RS00330	COG1609	Transcriptional regulator
EGX85_RS00335	COG0366	Alpha amylase catalytic
EGX85_RS00350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGX85_RS00355	COG1234	tRNA 3'-trailer cleavage
EGX85_RS00360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGX85_RS00385	COG0300	oxidoreductase activity
EGX85_RS00395	COG0667	Aldo Keto reductase
EGX85_RS00400	COG0494	nUDIX hydrolase
EGX85_RS00405	COG0735	belongs to the Fur family
EGX85_RS00410	COG4974	Belongs to the 'phage' integrase family
EGX85_RS00420	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EGX85_RS00425	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGX85_RS00430	COG1187	pseudouridine synthase activity
EGX85_RS00435	COG0745	RESPONSE REGULATOR receiver
EGX85_RS00450	COG1141	Ferredoxin
EGX85_RS00460	COG0514	ATP-dependent DNA helicase (RecQ)
EGX85_RS00465	COG1388	LysM domain
EGX85_RS00470	COG0492	ferredoxin-NADP+ reductase activity
EGX85_RS00480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EGX85_RS00485	COG0539	negative regulation of cytoplasmic translation
EGX85_RS00490	COG1160	GTP binding
EGX85_RS00495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EGX85_RS00515	COG2226	methyltransferase
EGX85_RS00520	COG0142	geranyltranstransferase activity
EGX85_RS00525	COG0105	UTP biosynthetic process
EGX85_RS00530	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EGX85_RS00535	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EGX85_RS00540	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGX85_RS00545	COG0457	Tetratricopeptide repeat
EGX85_RS00550	COG5582	Belongs to the UPF0302 family
EGX85_RS00555	COG4347	Protein of unknown function (DUF1405)
EGX85_RS00560	COG2738	Putative neutral zinc metallopeptidase
EGX85_RS00565	COG1694	Mazg nucleotide pyrophosphohydrolase
EGX85_RS00570	COG0438	transferase activity, transferring glycosyl groups
EGX85_RS00575	COG0617	tRNA 3'-terminal CCA addition
EGX85_RS00585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGX85_RS00585	COG1199	ATP-dependent helicase activity
EGX85_RS00590	COG0017	Asparaginyl-tRNA synthetase
EGX85_RS00595	COG3935	DnaD domain protein
EGX85_RS00600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX85_RS00610	COG4499	WXG100 protein secretion system (Wss), protein YukC
EGX85_RS00610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX85_RS00615	COG3331	DNA recombination
EGX85_RS00625	COG4474	Belongs to the UPF0398 family
EGX85_RS00630	COG3599	regulation of cell shape
EGX85_RS00640	COG0116	Belongs to the methyltransferase superfamily
EGX85_RS00650	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EGX85_RS00655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX85_RS00685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGX85_RS00695	COG1413	lyase activity
EGX85_RS00700	COG1413	lyase activity
EGX85_RS00710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EGX85_RS00730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGX85_RS00735	COG2190	(PTS) system
EGX85_RS00740	COG4479	Belongs to the UPF0346 family
EGX85_RS00745	COG0793	Belongs to the peptidase S41A family
EGX85_RS00755	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGX85_RS00760	COG0671	phosphoesterase, PA-phosphatase related
EGX85_RS00765	COG0745	RESPONSE REGULATOR receiver
EGX85_RS00770	COG5002	protein histidine kinase activity
EGX85_RS00775	COG0567	Dehydrogenase, E1 component
EGX85_RS00780	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX85_RS00800	COG0714	Associated with various cellular activities
EGX85_RS00805	COG4548	von Willebrand factor, type A
EGX85_RS00810	COG1114	Component of the transport system for branched-chain amino acids
EGX85_RS00820	COG3853	Toxic anion resistance protein (TelA)
EGX85_RS00830	COG1254	Belongs to the acylphosphatase family
EGX85_RS00840	COG1278	Cold shock
EGX85_RS00860	COG1473	amidohydrolase
EGX85_RS00865	COG2171	N-acyltransferase activity
EGX85_RS00870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGX85_RS00875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX85_RS00880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX85_RS00890	COG0488	(ABC) transporter
EGX85_RS00895	COG2996	Protein conserved in bacteria
EGX85_RS00900	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGX85_RS00905	COG0573	inorganic phosphate transmembrane transporter activity
EGX85_RS00910	COG0581	inorganic phosphate transmembrane transporter activity
EGX85_RS00915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGX85_RS00920	COG0704	Plays a role in the regulation of phosphate uptake
EGX85_RS00925	COG1164	Oligoendopeptidase f
EGX85_RS00935	COG4607	ABC-type enterochelin transport system periplasmic component
EGX85_RS00940	COG0561	phosphatase activity
EGX85_RS00945	COG2348	transferase activity, transferring amino-acyl groups
EGX85_RS00950	COG2348	transferase activity, transferring amino-acyl groups
EGX85_RS00960	COG0159	tryptophan synthase activity
EGX85_RS00970	COG0135	phosphoribosylanthranilate isomerase activity
EGX85_RS00975	COG0134	indole-3-glycerol-phosphate synthase activity
EGX85_RS00980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX85_RS00985	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX85_RS00990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGX85_RS00995	COG1363	Peptidase, m42
EGX85_RS01000	COG0287	Prephenate dehydrogenase
EGX85_RS01005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGX85_RS01010	COG1942	4-Oxalocrotonate Tautomerase
EGX85_RS01025	COG0392	lysyltransferase activity
EGX85_RS01025	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EGX85_RS01030	COG0628	permease
EGX85_RS01035	COG3711	transcriptional antiterminator
EGX85_RS01040	COG1115	amino acid carrier protein
EGX85_RS01045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX85_RS01050	COG0187	DNA topoisomerase II activity
EGX85_RS01055	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EGX85_RS01060	COG4841	protein insertion into membrane
EGX85_RS01065	COG0824	Thioesterase
EGX85_RS01075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGX85_RS01080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX85_RS01085	COG1970	mechanosensitive ion channel activity
EGX85_RS01090	COG0419	ATPase involved in DNA repair
EGX85_RS01095	COG0420	3'-5' exonuclease activity
EGX85_RS01100	COG4846	Membrane protein involved in cytochrome C biogenesis
EGX85_RS01115	COG4224	UPF0291 protein
EGX85_RS01125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGX85_RS01130	COG2340	Cysteine-rich secretory protein family
EGX85_RS01135	COG0516	GMP reductase activity
EGX85_RS01140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGX85_RS01150	COG0753	catalase activity
EGX85_RS01155	COG0833	amino acid
EGX85_RS01170	COG0083	homoserine kinase activity
EGX85_RS01175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EGX85_RS01180	COG0460	homoserine dehydrogenase
EGX85_RS01185	COG0527	aspartate kinase activity
EGX85_RS01215	COG2197	response regulator
EGX85_RS01220	COG4585	Histidine kinase
EGX85_RS01230	COG1131	(ABC) transporter
EGX85_RS01235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX85_RS01285	COG0789	Transcriptional regulator
EGX85_RS01290	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EGX85_RS01295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGX85_RS01300	COG0386	Belongs to the glutathione peroxidase family
EGX85_RS01305	COG1923	regulation of RNA biosynthetic process
EGX85_RS01310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EGX85_RS01320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX85_RS01325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX85_RS01330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGX85_RS01340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGX85_RS01345	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EGX85_RS01355	COG4550	Control of competence regulator ComK, YlbF/YmcA
EGX85_RS01360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGX85_RS01370	COG4195	phage-related replication protein
EGX85_RS01375	COG1013	pyruvate-flavodoxin oxidoreductase activity
EGX85_RS01380	COG0674	pyruvate-flavodoxin oxidoreductase activity
EGX85_RS01380	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EGX85_RS01385	COG1692	metallophosphoesterase
EGX85_RS01395	COG1418	mRNA catabolic process
EGX85_RS01405	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGX85_RS01410	COG1546	Belongs to the CinA family
EGX85_RS01410	COG1058	Belongs to the CinA family
EGX85_RS01430	COG0300	oxidoreductase activity
EGX85_RS01435	COG0612	Peptidase, M16
EGX85_RS01440	COG0612	Peptidase, M16
EGX85_RS01445	COG2188	Transcriptional regulator
EGX85_RS01450	COG1674	ftsk spoiiie
EGX85_RS01455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EGX85_RS01460	COG1185	polyribonucleotide nucleotidyltransferase activity
EGX85_RS01465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EGX85_RS01470	COG0196	riboflavin kinase activity
EGX85_RS01475	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGX85_RS01480	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EGX85_RS01485	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EGX85_RS01490	COG1358	cellular component organization or biogenesis
EGX85_RS01495	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EGX85_RS01500	COG0195	Participates in both transcription termination and antitermination
EGX85_RS01505	COG0779	Required for maturation of 30S ribosomal subunits
EGX85_RS01510	COG2176	DNA-directed DNA polymerase activity
EGX85_RS01515	COG0442	prolyl-tRNA aminoacylation
EGX85_RS01525	COG4589	Belongs to the CDS family
EGX85_RS01530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGX85_RS01535	COG0233	cytoplasmic translational termination
EGX85_RS01540	COG0528	UMP kinase activity
EGX85_RS01545	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EGX85_RS01550	COG0052	Belongs to the universal ribosomal protein uS2 family
EGX85_RS01555	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EGX85_RS01560	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EGX85_RS01565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EGX85_RS01570	COG4974	Belongs to the 'phage' integrase family
EGX85_RS01575	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EGX85_RS01580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX85_RS01585	COG0758	DNA mediated transformation
EGX85_RS01595	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGX85_RS01600	COG0045	succinate-CoA ligase (ADP-forming) activity
EGX85_RS01605	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGX85_RS01615	COG4485	Bacterial membrane protein, YfhO
EGX85_RS01625	COG0335	large ribosomal subunit rRNA binding
EGX85_RS01630	COG0336	Belongs to the RNA methyltransferase TrmD family
EGX85_RS01635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EGX85_RS01640	COG0228	four-way junction DNA binding
EGX85_RS01645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGX85_RS01650	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EGX85_RS01655	COG0552	protein localization to endoplasmic reticulum
EGX85_RS01660	COG1196	nuclear chromosome segregation
EGX85_RS01665	COG0571	ribonuclease III activity
EGX85_RS01670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX85_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
EGX85_RS01685	COG0416	fatty acid biosynthetic process
EGX85_RS01690	COG1349	DNA-binding transcription factor activity
EGX85_RS01705	COG1461	Dihydroxyacetone kinase
EGX85_RS01710	COG1302	Protein conserved in bacteria
EGX85_RS01715	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EGX85_RS01720	COG1564	THIamine pyrophosphokinase
EGX85_RS01725	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGX85_RS01730	COG1162	GTPase activity
EGX85_RS01740	COG0631	protein serine/threonine phosphatase activity
EGX85_RS01745	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EGX85_RS01750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGX85_RS01750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGX85_RS01755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EGX85_RS01770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGX85_RS01775	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGX85_RS01780	COG1758	RNA polymerase activity
EGX85_RS01785	COG0194	GDP metabolic process
EGX85_RS01805	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EGX85_RS01810	COG0284	orotidine-5'-phosphate decarboxylase activity
EGX85_RS01815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGX85_RS01820	COG0505	Belongs to the CarA family
EGX85_RS01830	COG0540	Belongs to the ATCase OTCase family
EGX85_RS01835	COG2233	PERMEase
EGX85_RS01840	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EGX85_RS01845	COG0564	pseudouridine synthase activity
EGX85_RS01850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EGX85_RS01855	COG1388	LysM domain
EGX85_RS01855	COG3942	CHAP domain
EGX85_RS01865	COG0702	epimerase
EGX85_RS01870	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGX85_RS01875	COG3599	regulation of cell shape
EGX85_RS01885	COG0762	integral membrane protein
EGX85_RS01890	COG1799	cell septum assembly
EGX85_RS01895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGX85_RS01900	COG1496	oxidoreductase activity
EGX85_RS01905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGX85_RS01910	COG0849	cell division
EGX85_RS01915	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGX85_RS01920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGX85_RS01925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGX85_RS01930	COG0768	penicillin binding
EGX85_RS01935	COG4839	cell division protein FtsL
EGX85_RS01940	COG0275	rRNA processing
EGX85_RS01945	COG2001	Belongs to the MraZ family
EGX85_RS01950	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EGX85_RS01955	COG0454	-acetyltransferase
EGX85_RS01960	COG1011	Hydrolase
EGX85_RS02005	COG1388	LysM domain
EGX85_RS02005	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX85_RS02170	COG0756	dUTP diphosphatase activity
EGX85_RS02235	COG1484	DNA-dependent DNA replication
EGX85_RS02245	COG3620	sequence-specific DNA binding
EGX85_RS02295	COG3646	Phage regulatory protein
EGX85_RS02295	COG3645	SOS response
EGX85_RS02325	COG0582	viral genome integration into host DNA
EGX85_RS02335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGX85_RS02340	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGX85_RS02345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGX85_RS02350	COG1053	succinate dehydrogenase
EGX85_RS02355	COG2009	succinate dehydrogenase
EGX85_RS02360	COG0322	excinuclease ABC activity
EGX85_RS02365	COG3118	belongs to the thioredoxin family
EGX85_RS02370	COG1193	negative regulation of DNA recombination
EGX85_RS02375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EGX85_RS02375	COG1796	DNA polymerase
EGX85_RS02385	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EGX85_RS02390	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGX85_RS02395	COG0072	phenylalanine-tRNA ligase activity
EGX85_RS02395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX85_RS02400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EGX85_RS02405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX85_RS02410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGX85_RS02425	COG1323	Belongs to the UPF0348 family
EGX85_RS02430	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EGX85_RS02435	COG0742	ribosomal rna small subunit methyltransferase
EGX85_RS02445	COG4471	UPF0298 protein
EGX85_RS02455	COG3679	Belongs to the UPF0342 family
EGX85_RS02460	COG2340	Cysteine-rich secretory protein family
EGX85_RS02470	COG0109	protoheme IX farnesyltransferase activity
EGX85_RS02475	COG1612	heme a metabolic process
EGX85_RS02485	COG0772	Belongs to the SEDS family
EGX85_RS02490	COG4838	Belongs to the UPF0358 family
EGX85_RS02495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGX85_RS02500	COG4896	Protein conserved in bacteria
EGX85_RS02505	COG1217	gtp-binding protein TYPA
EGX85_RS02515	COG0483	inositol monophosphate 1-phosphatase activity
EGX85_RS02520	COG4493	Belongs to the UPF0637 family
EGX85_RS02525	COG1914	H( )-stimulated, divalent metal cation uptake system
EGX85_RS02545	COG1177	transmembrane transport
EGX85_RS02550	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX85_RS02555	COG3842	ATPase activity
EGX85_RS02560	COG3800	Transcriptional regulator
EGX85_RS02560	COG1396	sequence-specific DNA binding
EGX85_RS02565	COG4476	Belongs to the UPF0223 family
EGX85_RS02595	COG0242	peptide deformylase activity
EGX85_RS02600	COG5503	Protein of unknown function (DUF1447)
EGX85_RS02605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EGX85_RS02615	COG2832	Protein of unknown function (DUF454)
EGX85_RS02620	COG0569	domain protein
EGX85_RS02625	COG1294	oxidase, subunit
EGX85_RS02630	COG1271	oxidase subunit
EGX85_RS02645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX85_RS02660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EGX85_RS02680	COG1122	ATPase activity
EGX85_RS02685	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EGX85_RS02690	COG0151	Belongs to the GarS family
EGX85_RS02695	COG0138	bifunctional purine biosynthesis protein purh
EGX85_RS02705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGX85_RS02715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGX85_RS02720	COG0047	phosphoribosylformylglycinamidine synthase activity
EGX85_RS02725	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGX85_RS02730	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EGX85_RS02735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGX85_RS02740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGX85_RS02745	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EGX85_RS02770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGX85_RS02775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGX85_RS02780	COG1845	cytochrome c oxidase, subunit III
EGX85_RS02785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGX85_RS02795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGX85_RS02805	COG1316	TRANSCRIPTIONal
EGX85_RS02835	COG3594	Acyltransferase
EGX85_RS02840	COG0436	Aminotransferase
EGX85_RS02845	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EGX85_RS02850	COG0596	Alpha beta hydrolase
EGX85_RS02855	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EGX85_RS02860	COG1169	isochorismate synthase
EGX85_RS02865	COG1575	Belongs to the MenA family. Type 1 subfamily
EGX85_RS02925	COG4873	Protein conserved in bacteria
EGX85_RS02945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGX85_RS02950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX85_RS02955	COG0861	Integral membrane protein TerC family
EGX85_RS02960	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EGX85_RS02970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX85_RS02975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGX85_RS02980	COG2814	Major facilitator Superfamily
EGX85_RS02985	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EGX85_RS02990	COG2382	esterase
EGX85_RS02995	COG0628	permease
EGX85_RS03005	COG0569	domain protein
EGX85_RS03005	COG0475	glutathione-regulated potassium exporter activity
EGX85_RS03010	COG2239	Acts as a magnesium transporter
EGX85_RS03015	COG0564	pseudouridine synthase activity
EGX85_RS03020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGX85_RS03025	COG2357	RelA SpoT domain protein
EGX85_RS03035	COG4116	CYTH
EGX85_RS03040	COG2346	COG2346, Truncated hemoglobins
EGX85_RS03045	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EGX85_RS03050	COG1164	Oligoendopeptidase f
EGX85_RS03060	COG4862	establishment of competence for transformation
EGX85_RS03065	COG1393	Belongs to the ArsC family
EGX85_RS03070	COG0180	Tryptophanyl-tRNA synthetase
EGX85_RS03075	COG4166	transmembrane transport
EGX85_RS03080	COG4608	Belongs to the ABC transporter superfamily
EGX85_RS03085	COG0444	Belongs to the ABC transporter superfamily
EGX85_RS03090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX85_RS03095	COG0601	transmembrane transport
EGX85_RS03110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGX85_RS03120	COG0542	response to heat
EGX85_RS03135	COG0561	phosphatase activity
EGX85_RS03140	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX85_RS03150	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGX85_RS03155	COG1074	ATP-dependent DNA helicase activity
EGX85_RS03160	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EGX85_RS03175	COG0398	Pfam SNARE associated Golgi protein
EGX85_RS03180	COG0166	Belongs to the GPI family
EGX85_RS03185	COG0137	argininosuccinate synthase activity
EGX85_RS03190	COG0165	Argininosuccinate lyase
EGX85_RS03195	COG0584	glycerophosphoryl diester phosphodiesterase
EGX85_RS03210	COG1902	pentaerythritol trinitrate reductase activity
EGX85_RS03220	COG1098	S1 RNA binding domain
EGX85_RS03225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX85_RS03235	COG2111	Na H antiporter
EGX85_RS03235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX85_RS03240	COG2111	Na H antiporter
EGX85_RS03245	COG1006	Multisubunit Na H antiporter MnhC subunit
EGX85_RS03250	COG0651	ATP synthesis coupled electron transport
EGX85_RS03255	COG1863	multisubunit Na H antiporter MnhE subunit
EGX85_RS03260	COG2212	antiporter activity
EGX85_RS03265	COG1320	monovalent cation:proton antiporter activity
EGX85_RS03275	COG2050	protein possibly involved in aromatic compounds catabolism
EGX85_RS03280	COG2056	Na+-H+ antiporter family
EGX85_RS03285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGX85_RS03290	COG1252	NADH dehydrogenase
EGX85_RS03295	COG0316	Belongs to the HesB IscA family
EGX85_RS03300	COG4844	belongs to the
EGX85_RS03305	COG1252	NADH dehydrogenase
EGX85_RS03310	COG4837	Protein of unknown function (DUF1462)
EGX85_RS03315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EGX85_RS03325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EGX85_RS03330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX85_RS03335	COG1696	Membrane protein involved in D-alanine export
EGX85_RS03340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX85_RS03355	COG0647	UMP catabolic process
EGX85_RS03360	COG2445	Protein of unknown function DUF86
EGX85_RS03370	COG4470	Protein conserved in bacteria
EGX85_RS03375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGX85_RS03380	COG0737	Belongs to the 5'-nucleotidase family
EGX85_RS03385	COG0730	response to heat
EGX85_RS03390	COG1801	Protein of unknown function DUF72
EGX85_RS03395	COG2070	2-Nitropropane dioxygenase
EGX85_RS03405	COG0719	Fe-S assembly protein
EGX85_RS03410	COG0822	iron-sulfur transferase activity
EGX85_RS03420	COG0719	Fe-S assembly protein
EGX85_RS03425	COG0396	ATPase activity
EGX85_RS03440	COG3237	CsbD-like
EGX85_RS03445	COG1464	Belongs to the NlpA lipoprotein family
EGX85_RS03450	COG2011	ABC-type metal ion transport system permease component
EGX85_RS03455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGX85_RS03465	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EGX85_RS03470	COG0509	glycine decarboxylation via glycine cleavage system
EGX85_RS03475	COG1393	Belongs to the ArsC family
EGX85_RS03480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX85_RS03490	COG0710	3-dehydroquinate dehydratase activity
EGX85_RS03495	COG1764	response to oxidative stress
EGX85_RS03505	COG1279	arginine transmembrane transporter activity
EGX85_RS03510	COG0406	alpha-ribazole phosphatase activity
EGX85_RS03550	COG0456	acetyltransferase
EGX85_RS03555	COG4195	phage-related replication protein
EGX85_RS03585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EGX85_RS03590	COG0557	exoribonuclease II activity
EGX85_RS03595	COG1647	Serine aminopeptidase, S33
EGX85_RS03600	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX85_RS03610	COG0148	phosphopyruvate hydratase activity
EGX85_RS03615	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EGX85_RS03620	COG0149	triose-phosphate isomerase activity
EGX85_RS03625	COG0126	phosphoglycerate kinase activity
EGX85_RS03635	COG2390	Transcriptional regulator
EGX85_RS03655	COG1090	epimerase
EGX85_RS03665	COG0740	serine-type endopeptidase activity
EGX85_RS03675	COG1481	regulation of sporulation
EGX85_RS03680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EGX85_RS03685	COG1660	Displays ATPase and GTPase activities
EGX85_RS03690	COG0492	ferredoxin-NADP+ reductase activity
EGX85_RS03705	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EGX85_RS03710	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EGX85_RS03715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX85_RS03720	COG0556	nucleotide-excision repair
EGX85_RS03740	COG0300	oxidoreductase activity
EGX85_RS03745	COG1388	LysM domain
EGX85_RS03745	COG3942	CHAP domain
EGX85_RS03755	COG0653	protein targeting
EGX85_RS03760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGX85_RS03765	COG1040	competence protein
EGX85_RS03780	COG1739	Uncharacterized protein family UPF0029
EGX85_RS03785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGX85_RS03790	COG2199	diguanylate cyclase activity
EGX85_RS03805	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX85_RS03810	COG1929	Belongs to the glycerate kinase type-1 family
EGX85_RS03830	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGX85_RS03845	COG4607	ABC-type enterochelin transport system periplasmic component
EGX85_RS03850	COG4604	ABC transporter, ATP-binding protein
EGX85_RS03855	COG4605	iron ion homeostasis
EGX85_RS03860	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX85_RS03865	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX85_RS03870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX85_RS03875	COG1780	Probably involved in ribonucleotide reductase function
EGX85_RS03885	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EGX85_RS03890	COG3104	oligopeptide transport
EGX85_RS03900	COG1597	lipid kinase activity
EGX85_RS03910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGX85_RS03915	COG3104	oligopeptide transport
EGX85_RS03920	COG1174	glycine betaine transport
EGX85_RS03930	COG0514	ATP-dependent DNA helicase (RecQ)
EGX85_RS03935	COG0488	(ABC) transporter
EGX85_RS03950	COG1368	sulfuric ester hydrolase activity
EGX85_RS03955	COG1984	allophanate hydrolase subunit 2
EGX85_RS03960	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGX85_RS03980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX85_RS03980	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX85_RS03985	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EGX85_RS03990	COG0720	synthase
EGX85_RS03995	COG0602	queuosine metabolic process
EGX85_RS04005	COG0463	Glycosyl transferase, family 2
EGX85_RS04015	COG0656	L-ascorbic acid biosynthetic process
EGX85_RS04020	COG1253	flavin adenine dinucleotide binding
EGX85_RS04025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX85_RS04025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX85_RS04025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX85_RS04030	COG1105	Belongs to the carbohydrate kinase PfkB family
EGX85_RS04035	COG1349	DNA-binding transcription factor activity
EGX85_RS04040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGX85_RS04085	COG0415	Belongs to the DNA photolyase family
EGX85_RS04090	COG0471	metal ion transport
EGX85_RS04100	COG0523	cobalamin synthesis protein
EGX85_RS04110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGX85_RS04115	COG4988	ABC transporter
EGX85_RS04120	COG1968	undecaprenyl-diphosphatase activity
EGX85_RS04130	COG1671	Belongs to the UPF0178 family
EGX85_RS04135	COG1611	Belongs to the LOG family
EGX85_RS04140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX85_RS04155	COG0456	acetyltransferase
EGX85_RS04165	COG2839	Protein conserved in bacteria
EGX85_RS04175	COG0583	DNA-binding transcription factor activity
EGX85_RS04195	COG0217	transcriptional regulatory protein
EGX85_RS04215	COG3942	CHAP domain
EGX85_RS04215	COG1388	LysM domain
EGX85_RS04220	COG0306	phosphate transporter
EGX85_RS04225	COG1392	Phosphate transport regulator
EGX85_RS04230	COG0577	efflux transmembrane transporter activity
EGX85_RS04235	COG1136	(ABC) transporter
EGX85_RS04240	COG2205	protein histidine kinase activity
EGX85_RS04245	COG0745	RESPONSE REGULATOR receiver
EGX85_RS04250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX85_RS04260	COG0657	acetylesterase activity
EGX85_RS04265	COG3949	Membrane
EGX85_RS04280	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EGX85_RS04290	COG2376	Dihydroxyacetone kinase
EGX85_RS04295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX85_RS04300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX85_RS04305	COG1120	ATPase activity
EGX85_RS04310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGX85_RS04315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX85_RS04320	COG0463	Glycosyl transferase, family 2
EGX85_RS04320	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX85_RS04330	COG1132	(ABC) transporter
EGX85_RS04335	COG1686	Belongs to the peptidase S11 family
EGX85_RS04340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EGX85_RS04350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX85_RS04355	COG1682	transport, permease protein
EGX85_RS04360	COG1134	teichoic acid transport
EGX85_RS04365	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EGX85_RS04375	COG1321	iron dependent repressor
EGX85_RS04400	COG1320	monovalent cation:proton antiporter activity
EGX85_RS04405	COG2212	antiporter activity
EGX85_RS04410	COG1863	multisubunit Na H antiporter MnhE subunit
EGX85_RS04415	COG0651	ATP synthesis coupled electron transport
EGX85_RS04420	COG1006	Multisubunit Na H antiporter MnhC subunit
EGX85_RS04425	COG2111	Na H antiporter
EGX85_RS04430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX85_RS04430	COG2111	Na H antiporter
EGX85_RS04495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX85_RS04500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX85_RS04515	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX85_RS04520	COG0018	arginyl-trna synthetase
EGX85_RS04575	COG0456	acetyltransferase
EGX85_RS04590	COG1131	(ABC) transporter
EGX85_RS04600	COG3173	Aminoglycoside phosphotransferase
EGX85_RS04610	COG3226	Transcriptional regulator
EGX85_RS04700	COG1078	dGTPase activity
EGX85_RS04710	COG0655	NAD(P)H dehydrogenase (quinone) activity
EGX85_RS04715	COG0667	Aldo Keto reductase
EGX85_RS04725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX85_RS04730	COG1278	Cold shock
EGX85_RS04735	COG4844	belongs to the
EGX85_RS04760	COG0095	Lipoate-protein ligase
EGX85_RS04770	COG3253	May function as heme-dependent peroxidase
EGX85_RS04775	COG2966	Psort location CytoplasmicMembrane, score
EGX85_RS04790	COG2363	Small membrane protein
EGX85_RS04800	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EGX85_RS04830	COG0183	Belongs to the thiolase family
EGX85_RS04835	COG0318	PFAM AMP-dependent synthetase and ligase
EGX85_RS04880	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGX85_RS04885	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EGX85_RS04895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGX85_RS04900	COG1469	GTP cyclohydrolase I activity
EGX85_RS04935	COG0431	NADPH-dependent FMN reductase
EGX85_RS04940	COG0561	phosphatase activity
EGX85_RS04950	COG1428	Deoxynucleoside kinase
EGX85_RS04955	COG1428	Deoxynucleoside kinase
EGX85_RS04960	COG0546	phosphoglycolate phosphatase activity
EGX85_RS05005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX85_RS05010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX85_RS05015	COG0737	Belongs to the 5'-nucleotidase family
EGX85_RS05040	COG1473	amidohydrolase
EGX85_RS05045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EGX85_RS05050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EGX85_RS05060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGX85_RS05070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EGX85_RS05075	COG0085	RNA polymerase activity
EGX85_RS05080	COG2813	Specifically methylates the guanine in position
EGX85_RS05085	COG0222	ribosome binding
EGX85_RS05090	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EGX85_RS05100	COG0081	regulation of translation
EGX85_RS05105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EGX85_RS05110	COG0250	Participates in transcription elongation, termination and antitermination
EGX85_RS05115	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX85_RS05120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGX85_RS05130	COG3688	RNA-binding protein containing a PIN domain
EGX85_RS05135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX85_RS05140	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EGX85_RS05145	COG0215	cysteine-tRNA ligase activity
EGX85_RS05150	COG1045	serine acetyltransferase
EGX85_RS05155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGX85_RS05160	COG4956	integral membrane protein (PIN domain superfamily)
EGX85_RS05165	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EGX85_RS05170	COG0542	response to heat
EGX85_RS05175	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EGX85_RS05180	COG3880	PFAM UvrB UvrC protein
EGX85_RS05185	COG4463	regulation of RNA biosynthetic process
EGX85_RS05190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX85_RS05195	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EGX85_RS05200	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EGX85_RS05205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX85_RS05210	COG2259	Doxx family
EGX85_RS05295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGX85_RS05300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGX85_RS05315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGX85_RS05320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EGX85_RS05325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGX85_RS05335	COG0037	tRNA processing
EGX85_RS05340	COG1098	S1 RNA binding domain
EGX85_RS05350	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGX85_RS05355	COG3956	TIGRFAM MazG family protein
EGX85_RS05360	COG2244	polysaccharide biosynthetic process
EGX85_RS05365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGX85_RS05370	COG0193	aminoacyl-tRNA hydrolase activity
EGX85_RS05375	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EGX85_RS05380	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGX85_RS05385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGX85_RS05390	COG2088	sporulation resulting in formation of a cellular spore
EGX85_RS05395	COG0251	oxidation-reduction process
EGX85_RS05400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX85_RS05405	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EGX85_RS05410	COG4466	Protein conserved in bacteria
EGX85_RS05415	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGX85_RS05420	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EGX85_RS05425	COG0084	hydrolase, TatD family'
EGX85_RS05430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX85_RS05430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX85_RS05435	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGX85_RS05440	COG2827	Endonuclease containing a URI domain
EGX85_RS05445	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EGX85_RS05450	COG4467	Involved in initiation control of chromosome replication
EGX85_RS05455	COG1774	PSP1 C-terminal conserved region
EGX85_RS05460	COG0470	DNA polymerase III
EGX85_RS05470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EGX85_RS05475	COG1982	Orn Lys Arg decarboxylase major
EGX85_RS05500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EGX85_RS05510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGX85_RS05525	COG2188	Transcriptional regulator
EGX85_RS05530	COG0366	Alpha amylase catalytic
EGX85_RS05535	COG1263	PTS System
EGX85_RS05535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX85_RS05545	COG0493	'glutamate synthase
EGX85_RS05550	COG0070	glutamate synthase
EGX85_RS05550	COG0069	glutamate synthase activity
EGX85_RS05550	COG0067	glutamate synthase
EGX85_RS05585	COG1388	LysM domain
EGX85_RS05585	COG3942	CHAP domain
EGX85_RS05590	COG0626	cystathionine gamma-synthase activity
EGX85_RS05595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGX85_RS05610	COG0733	neurotransmitter:sodium symporter activity
EGX85_RS05625	COG1647	Serine aminopeptidase, S33
EGX85_RS05635	COG0671	phosphoesterase, PA-phosphatase related
EGX85_RS05645	COG5609	conserved protein (DUF2294)
EGX85_RS05650	COG3002	Belongs to the UPF0753 family
EGX85_RS05655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX85_RS05665	COG3759	membrane
EGX85_RS05680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGX85_RS05690	COG3728	DNA packaging
EGX85_RS05690	COG5484	DNA packaging
EGX85_RS05740	COG0519	Catalyzes the synthesis of GMP from XMP
EGX85_RS05740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGX85_RS05745	COG0517	IMP dehydrogenase activity
EGX85_RS05745	COG0516	GMP reductase activity
EGX85_RS05750	COG2233	PERMEase
EGX85_RS05755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX85_RS05775	COG1823	symporter activity
EGX85_RS05780	COG0778	Nitroreductase
EGX85_RS05790	COG0450	alkyl hydroperoxide reductase
EGX85_RS05795	COG3634	alkyl hydroperoxide reductase activity
EGX85_RS05805	COG0406	alpha-ribazole phosphatase activity
EGX85_RS05810	COG1280	lysine exporter protein (LysE YggA)
EGX85_RS05880	COG3682	Transcriptional regulator
EGX85_RS05890	COG1012	belongs to the aldehyde dehydrogenase family
EGX85_RS05900	COG1902	pentaerythritol trinitrate reductase activity
EGX85_RS05950	COG0456	acetyltransferase
EGX85_RS05985	COG1131	(ABC) transporter
EGX85_RS06035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGX85_RS06045	COG0360	Binds together with S18 to 16S ribosomal RNA
EGX85_RS06060	COG0012	GTP binding
EGX85_RS06065	COG4481	Protein conserved in bacteria
EGX85_RS06070	COG0668	transmembrane transport
EGX85_RS06075	COG1475	DNA binding
EGX85_RS06080	COG0626	cystathionine gamma-synthase activity
EGX85_RS06085	COG0626	cystathionine gamma-synthase activity
EGX85_RS06090	COG0646	methionine synthase
EGX85_RS06090	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EGX85_RS06095	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EGX85_RS06110	COG0488	(ABC) transporter
EGX85_RS06120	COG0346	lactoylglutathione lyase activity
EGX85_RS06160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EGX85_RS06195	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EGX85_RS06215	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EGX85_RS06265	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGX85_RS06270	COG3246	L-lysine catabolic process to acetate
EGX85_RS06275	COG1309	transcriptional regulator
EGX85_RS06290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX85_RS06295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX85_RS06320	COG1136	(ABC) transporter
EGX85_RS06325	COG0577	efflux transmembrane transporter activity
EGX85_RS06365	COG0357	Ribosomal RNA small subunit methyltransferase G
EGX85_RS06370	COG0445	tRNA wobble uridine modification
EGX85_RS06375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EGX85_RS06380	COG0594	ribonuclease P activity
EGX85_RS06390	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGX85_RS06395	COG0592	DNA-directed DNA polymerase activity
EGX85_RS06400	COG2501	S4 domain
EGX85_RS06405	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGX85_RS06410	COG0187	DNA topoisomerase II activity
EGX85_RS06415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX85_RS06420	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGX85_RS06425	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EGX85_RS06430	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGX85_RS06440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGX85_RS06450	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EGX85_RS06455	COG0359	binds to the 23S rRNA
EGX85_RS06460	COG0305	Participates in initiation and elongation during chromosome replication
EGX85_RS06465	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGX85_RS06480	COG0745	RESPONSE REGULATOR receiver
EGX85_RS06485	COG5002	protein histidine kinase activity
EGX85_RS06490	COG4863	YycH protein
EGX85_RS06505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGX85_RS06510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EGX85_RS06530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX85_RS06530	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX85_RS06570	COG3425	synthase
EGX85_RS06580	COG0584	glycerophosphoryl diester phosphodiesterase
EGX85_RS06585	COG2030	dehydratase
EGX85_RS06685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX85_RS06710	COG0640	Transcriptional regulator
EGX85_RS06720	COG2217	Heavy metal translocating P-type atpase
EGX85_RS06725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX85_RS06730	COG2210	Belongs to the sulfur carrier protein TusA family
EGX85_RS06735	COG1937	Protein conserved in bacteria
EGX85_RS06740	COG0730	response to heat
EGX85_RS06750	COG1388	LysM domain
EGX85_RS06755	COG1397	ADP-ribosylglycohydrolase
EGX85_RS06775	COG0789	Transcriptional regulator
EGX85_RS06785	COG0702	epimerase
EGX85_RS06790	COG2130	NADP-dependent
EGX85_RS06805	COG0640	Transcriptional regulator
EGX85_RS06810	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX85_RS06825	COG2217	Heavy metal translocating P-type atpase
EGX85_RS06830	COG1388	LysM domain
EGX85_RS06845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX85_RS06850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX85_RS06865	COG0668	transmembrane transport
EGX85_RS06880	COG0523	cobalamin synthesis protein
EGX85_RS06885	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX85_RS06895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGX85_RS06915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EGX85_RS06950	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX85_RS06955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX85_RS06960	COG1121	(ABC) transporter
EGX85_RS06965	COG0523	cobalamin synthesis protein
EGX85_RS06970	COG1114	Component of the transport system for branched-chain amino acids
EGX85_RS06985	COG0747	negative chemotaxis
EGX85_RS06995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX85_RS07000	COG4172	Belongs to the ABC transporter superfamily
EGX85_RS07030	COG0789	Transcriptional regulator
EGX85_RS07040	COG1253	flavin adenine dinucleotide binding
EGX85_RS07045	COG1959	2 iron, 2 sulfur cluster binding
EGX85_RS07050	COG2910	NAD(P)H-binding
EGX85_RS07075	COG1113	amino acid transport
EGX85_RS07080	COG0778	Nitroreductase
EGX85_RS07125	COG1609	Transcriptional regulator
EGX85_RS07130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX85_RS07135	COG1869	D-ribose catabolic process
EGX85_RS07145	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX85_RS07150	COG1879	ABC-type sugar transport system periplasmic component
EGX85_RS07160	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EGX85_RS07165	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EGX85_RS07170	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EGX85_RS07180	COG1876	peptidase activity
EGX85_RS07185	COG1737	Transcriptional regulator
EGX85_RS07190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX85_RS07195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX85_RS07200	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGX85_RS07215	COG2971	BadF BadG BcrA BcrD
EGX85_RS07225	COG3152	Membrane
EGX85_RS07235	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EGX85_RS07245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX85_RS07250	COG1288	antiporter activity
EGX85_RS07265	COG2318	DinB family
EGX85_RS07290	COG1028	Short-chain dehydrogenase reductase Sdr
EGX85_RS07310	COG1012	belongs to the aldehyde dehydrogenase family
EGX85_RS07315	COG1063	alcohol dehydrogenase
EGX85_RS07320	COG1846	Transcriptional regulator
EGX85_RS07325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX85_RS07340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGX85_RS07350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX85_RS07355	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGX85_RS07360	COG0022	dehydrogenase e1 component
EGX85_RS07365	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX85_RS07370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX85_RS07375	COG1695	Transcriptional regulator
EGX85_RS07385	COG1028	Short-chain dehydrogenase reductase Sdr
EGX85_RS07390	COG0246	Mannitol dehydrogenase
EGX85_RS07400	COG3711	transcriptional antiterminator
EGX85_RS07405	COG2213	PTS system mannitol-specific
EGX85_RS07410	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EGX85_RS07415	COG2962	Rard protein
EGX85_RS07425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX85_RS07435	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EGX85_RS07440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGX85_RS07475	COG0789	Transcriptional regulator
EGX85_RS07500	COG2314	TM2 domain
EGX85_RS07520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EGX85_RS07525	COG0549	Belongs to the carbamate kinase family
EGX85_RS07535	COG3093	addiction module antidote protein HigA
EGX85_RS07565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX85_RS07575	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EGX85_RS07585	COG0471	metal ion transport
EGX85_RS07590	COG5505	Protein of unknown function (DUF819)
EGX85_RS07595	COG4336	lyase activity
EGX85_RS07610	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGX85_RS07620	COG0363	glucosamine-6-phosphate deaminase activity
EGX85_RS07625	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EGX85_RS07640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX85_RS07645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX85_RS07670	COG1124	(ABC) transporter
EGX85_RS07675	COG0444	Belongs to the ABC transporter superfamily
EGX85_RS07690	COG0747	negative chemotaxis
EGX85_RS07695	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EGX85_RS07715	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EGX85_RS07725	COG1054	Belongs to the UPF0176 family
EGX85_RS07730	COG3386	PFAM SMP-30 Gluconolaconase
EGX85_RS07735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGX85_RS07755	COG4716	Myosin-crossreactive antigen
EGX85_RS07775	COG1131	(ABC) transporter
EGX85_RS07785	COG1476	TRANSCRIPTIONal
EGX85_RS07790	COG1959	2 iron, 2 sulfur cluster binding
EGX85_RS07795	COG0697	spore germination
EGX85_RS07800	COG2814	Major facilitator Superfamily
EGX85_RS07810	COG0737	Belongs to the 5'-nucleotidase family
EGX85_RS07820	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EGX85_RS07825	COG3639	organic phosphonate transmembrane transporter activity
EGX85_RS07850	COG3391	amine dehydrogenase activity
EGX85_RS07855	COG0201	protein transport
EGX85_RS07875	COG0653	protein targeting
EGX85_RS07890	COG0642	Histidine kinase
EGX85_RS07895	COG0745	RESPONSE REGULATOR receiver
EGX85_RS07915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGX85_RS07935	COG2814	Major facilitator Superfamily
EGX85_RS07945	COG2113	Glycine betaine
EGX85_RS07950	COG2409	Drug exporters of the RND superfamily
EGX85_RS07955	COG0583	DNA-binding transcription factor activity
EGX85_RS07960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGX85_RS07970	COG1288	antiporter activity
EGX85_RS07975	COG2190	(PTS) system
EGX85_RS07975	COG1263	PTS System
EGX85_RS07975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX85_RS07980	COG3942	CHAP domain
EGX85_RS07980	COG1705	Flagellar rod assembly protein muramidase FlgJ
EGX85_RS07980	COG1705	Flagellar rod assembly protein muramidase FlgJ
EGX85_RS07980	COG3942	CHAP domain
EGX85_RS08015	COG2235	arginine
EGX85_RS08025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGX85_RS08050	COG5658	integral membrane protein
EGX85_RS08055	COG2843	Capsule synthesis protein
EGX85_RS08060	COG3961	Belongs to the TPP enzyme family
EGX85_RS08085	COG4195	phage-related replication protein
EGX85_RS08110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGX85_RS08115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGX85_RS08155	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGX85_RS08180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGX85_RS08185	COG1316	TRANSCRIPTIONal
EGX85_RS08190	COG1785	Belongs to the alkaline phosphatase family
EGX85_RS08205	COG2205	protein histidine kinase activity
EGX85_RS08210	COG1136	(ABC) transporter
EGX85_RS08240	COG0175	sulfate reduction
EGX85_RS08245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGX85_RS08250	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX85_RS08265	COG0730	response to heat
EGX85_RS08270	COG2046	Belongs to the sulfate adenylyltransferase family
EGX85_RS08275	COG0529	Catalyzes the synthesis of activated sulfate
EGX85_RS08280	COG2851	Citrate transporter
EGX85_RS08295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EGX85_RS08300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX85_RS08305	COG1510	regulation of RNA biosynthetic process
EGX85_RS08310	COG1012	belongs to the aldehyde dehydrogenase family
EGX85_RS08315	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EGX85_RS08325	COG1473	amidohydrolase
EGX85_RS08335	COG1473	amidohydrolase
EGX85_RS08350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGX85_RS08360	COG0583	DNA-binding transcription factor activity
EGX85_RS08370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX85_RS08370	COG0574	Belongs to the PEP-utilizing enzyme family
EGX85_RS08375	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EGX85_RS08380	COG0579	oxidoreductase
EGX85_RS08390	COG2723	6-phospho-beta-galactosidase activity
EGX85_RS08410	COG3588	fructose-bisphosphate aldolase
EGX85_RS08415	COG0563	adenylate kinase activity
EGX85_RS08445	COG1464	Belongs to the NlpA lipoprotein family
EGX85_RS08455	COG0531	amino acid
EGX85_RS08460	COG0028	Belongs to the TPP enzyme family
EGX85_RS08465	COG3527	Alpha-acetolactate decarboxylase
EGX85_RS08495	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGX85_RS08505	COG0167	dihydroorotate dehydrogenase activity
EGX85_RS08510	COG3001	Fructosamine kinase
EGX85_RS08545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX85_RS08570	COG0741	lytic transglycosylase activity
EGX85_RS08580	COG1233	COG1233 Phytoene dehydrogenase and related
EGX85_RS08585	COG0463	Glycosyl transferase, family 2
EGX85_RS08590	COG1562	ergosterol biosynthetic process
EGX85_RS08595	COG1233	COG1233 Phytoene dehydrogenase and related
EGX85_RS08600	COG0436	Aminotransferase
EGX85_RS08610	COG2608	mercury ion transmembrane transporter activity
EGX85_RS08615	COG2217	Heavy metal translocating P-type atpase
EGX85_RS08625	COG1028	Short-chain dehydrogenase reductase Sdr
EGX85_RS08630	COG0110	maltose O-acetyltransferase activity
EGX85_RS08635	COG1012	belongs to the aldehyde dehydrogenase family
EGX85_RS08660	COG0598	Magnesium transport protein CorA
EGX85_RS08670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX85_RS08675	COG3425	synthase
EGX85_RS08690	COG3942	CHAP domain
EGX85_RS08690	COG1388	LysM domain
EGX85_RS08700	COG0583	DNA-binding transcription factor activity
EGX85_RS08705	COG1380	Effector of murein hydrolase LrgA
EGX85_RS08710	COG1346	cytolysis
EGX85_RS08715	COG0028	Belongs to the TPP enzyme family
EGX85_RS08725	COG2190	(PTS) system
EGX85_RS08725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX85_RS08725	COG1263	PTS System
EGX85_RS08730	COG1063	alcohol dehydrogenase
EGX85_RS08740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX85_RS08745	COG0039	L-malate dehydrogenase activity
EGX85_RS08755	COG0697	spore germination
EGX85_RS08765	COG1917	Cupin 2, conserved barrel domain protein
EGX85_RS08765	COG2207	Transcriptional regulator
EGX85_RS08775	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGX85_RS08795	COG1070	Carbohydrate kinase
EGX85_RS08805	COG1760	l-serine dehydratase
EGX85_RS08810	COG1760	l-serine dehydratase
EGX85_RS08825	COG3764	Sortase (surface protein transpeptidase)
EGX85_RS08840	COG0778	Nitroreductase
EGX85_RS08845	COG1012	belongs to the aldehyde dehydrogenase family
EGX85_RS08855	COG2514	catechol 2,3-dioxygenase activity
EGX85_RS08870	COG1012	belongs to the aldehyde dehydrogenase family
EGX85_RS08875	COG1846	Transcriptional regulator
EGX85_RS08880	COG0346	lactoylglutathione lyase activity
EGX85_RS08885	COG0346	lactoylglutathione lyase activity
EGX85_RS08890	COG0400	carboxylic ester hydrolase activity
EGX85_RS08895	COG3949	Membrane
EGX85_RS08905	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EGX85_RS08910	COG0586	Pfam SNARE associated Golgi protein
EGX85_RS08920	COG2022	thiamine diphosphate biosynthetic process
EGX85_RS08925	COG2104	thiamine diphosphate biosynthetic process
EGX85_RS08925	COG2022	thiamine diphosphate biosynthetic process
EGX85_RS08930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGX85_RS08940	COG2271	Major facilitator Superfamily
EGX85_RS08955	COG4876	unkown
EGX85_RS08960	COG2357	RelA SpoT domain protein
EGX85_RS08975	COG1802	Transcriptional regulator
EGX85_RS08980	COG1070	Carbohydrate kinase
EGX85_RS08985	COG2610	gluconate transmembrane transporter activity
EGX85_RS08995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX85_RS09000	COG0494	nUDIX hydrolase
EGX85_RS09025	COG4221	oxidoreductase activity
EGX85_RS09030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGX85_RS09035	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGX85_RS09040	COG0248	Ppx GppA phosphatase
EGX85_RS09045	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EGX85_RS09050	COG1028	Short-chain dehydrogenase reductase Sdr
EGX85_RS09055	COG1363	Peptidase, m42
EGX85_RS09070	COG0069	glutamate synthase activity
EGX85_RS09085	COG4619	ABC transporter
EGX85_RS09090	COG0390	transport system, permease component
EGX85_RS09095	COG2205	protein histidine kinase activity
EGX85_RS09100	COG0745	RESPONSE REGULATOR receiver
EGX85_RS09110	COG2814	Major facilitator Superfamily
EGX85_RS09115	COG2272	Belongs to the type-B carboxylesterase lipase family
EGX85_RS09120	COG0531	amino acid
EGX85_RS09125	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EGX85_RS09130	COG1063	alcohol dehydrogenase
EGX85_RS09150	COG1174	glycine betaine transport
EGX85_RS09155	COG1346	cytolysis
EGX85_RS09160	COG1380	Effector of murein hydrolase LrgA
EGX85_RS09165	COG3279	Response regulator of the LytR AlgR family
EGX85_RS09170	COG3275	phosphorelay sensor kinase activity
EGX85_RS09180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGX85_RS09185	COG3477	response to acidic pH
EGX85_RS09195	COG0706	membrane insertase activity
EGX85_RS09205	COG0531	amino acid
EGX85_RS09215	COG1113	amino acid transport
EGX85_RS09235	COG2226	methyltransferase
EGX85_RS09240	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EGX85_RS09245	COG2814	Major facilitator Superfamily
EGX85_RS09255	COG1929	Belongs to the glycerate kinase type-1 family
EGX85_RS09270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EGX85_RS09275	COG0741	lytic transglycosylase activity
EGX85_RS09280	COG0588	phosphoglycerate mutase activity
EGX85_RS09290	COG2814	Major facilitator Superfamily
EGX85_RS09295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX85_RS09300	COG0765	amino acid transport
EGX85_RS09305	COG1126	abc transporter atp-binding protein
EGX85_RS09325	COG3443	Belongs to the bacterial solute-binding protein 9 family
EGX85_RS09325	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX85_RS09330	COG2353	YceI-like domain
EGX85_RS09355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX85_RS09360	COG2146	nitrite reductase [NAD(P)H] activity
EGX85_RS09370	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EGX85_RS09375	COG1140	nitrate reductase beta subunit
EGX85_RS09380	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EGX85_RS09385	COG2181	nitrate reductase activity
EGX85_RS09395	COG4585	Histidine kinase
EGX85_RS09400	COG2197	response regulator
EGX85_RS09405	COG2223	nitrite transmembrane transporter activity
EGX85_RS09415	COG1846	Transcriptional regulator
EGX85_RS09435	COG3871	stress protein (general stress protein 26)
EGX85_RS09450	COG1263	PTS System
EGX85_RS09450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX85_RS09465	COG1511	domain protein
EGX85_RS09495	COG0492	ferredoxin-NADP+ reductase activity
EGX85_RS09505	COG0604	alcohol dehydrogenase
EGX85_RS09510	COG2822	iron ion transport
EGX85_RS09515	COG2837	iron assimilation
EGX85_RS09520	COG0672	)-iron permease
EGX85_RS09525	COG0805	protein transport
EGX85_RS09530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGX85_RS09540	COG0463	Glycosyl transferase, family 2
EGX85_RS09540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EGX85_RS09545	COG1620	l-lactate permease
EGX85_RS09550	COG0438	transferase activity, transferring glycosyl groups
EGX85_RS09555	COG0579	oxidoreductase
EGX85_RS09570	COG5002	protein histidine kinase activity
EGX85_RS09570	COG3850	Histidine kinase
EGX85_RS09575	COG0745	RESPONSE REGULATOR receiver
EGX85_RS09580	COG0577	efflux transmembrane transporter activity
EGX85_RS09585	COG1136	(ABC) transporter
EGX85_RS09600	COG4640	response to antibiotic
EGX85_RS09605	COG2814	Major facilitator Superfamily
EGX85_RS09615	COG1566	PFAM secretion protein HlyD family protein
EGX85_RS09620	COG2814	Major facilitator Superfamily
EGX85_RS09645	COG0598	Magnesium transport protein CorA
EGX85_RS09650	COG1304	FMN binding
EGX85_RS09655	COG0786	glutamate:sodium symporter activity
EGX85_RS09660	COG2094	Belongs to the DNA glycosylase MPG family
EGX85_RS09675	COG1742	UPF0060 membrane protein
EGX85_RS09685	COG2258	MOSC domain
EGX85_RS09690	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGX85_RS09695	COG1266	CAAX protease self-immunity
EGX85_RS09700	COG0010	Belongs to the arginase family
EGX85_RS09710	COG1473	amidohydrolase
EGX85_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
EGX85_RS09720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGX85_RS09735	COG1737	Transcriptional regulator
EGX85_RS09740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX85_RS09740	COG1263	PTS System
EGX85_RS09750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX85_RS09770	COG1113	amino acid transport
EGX85_RS09780	COG1263	PTS System
EGX85_RS09780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX85_RS09785	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EGX85_RS09800	COG2378	regulation of single-species biofilm formation
EGX85_RS09810	COG1316	TRANSCRIPTIONal
EGX85_RS09815	COG3383	formate dehydrogenase (NAD+) activity
EGX85_RS09820	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EGX85_RS09840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX85_RS09845	COG2076	Multidrug Resistance protein
EGX85_RS09850	COG2076	Multidrug Resistance protein
EGX85_RS09855	COG3942	CHAP domain
EGX85_RS09870	COG1757	Na H antiporter
EGX85_RS09880	COG3942	CHAP domain
EGX85_RS09905	COG1960	acyl-CoA dehydrogenase activity
EGX85_RS09910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX85_RS09915	COG1957	nucleoside hydrolase
EGX85_RS09920	COG1268	BioY protein
EGX85_RS09930	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EGX85_RS09935	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGX85_RS09940	COG4149	molybdate abc transporter
EGX85_RS09945	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EGX85_RS09950	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGX85_RS09960	COG0315	cyclic pyranopterin monophosphate synthase activity
EGX85_RS09985	COG0746	molybdenum cofactor guanylyltransferase activity
EGX85_RS09990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGX85_RS10020	COG2348	transferase activity, transferring amino-acyl groups
EGX85_RS10025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX85_RS10045	COG4975	Glucose uptake
EGX85_RS10055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX85_RS10055	COG0551	DNA topoisomerase type I activity
EGX85_RS10060	COG2252	PERMEase
EGX85_RS10070	COG0051	transcription antitermination factor activity, RNA binding
EGX85_RS10075	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EGX85_RS10080	COG0088	Forms part of the polypeptide exit tunnel
EGX85_RS10085	COG0089	rRNA binding
EGX85_RS10090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EGX85_RS10095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGX85_RS10100	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EGX85_RS10105	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EGX85_RS10110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGX85_RS10115	COG0255	Belongs to the universal ribosomal protein uL29 family
EGX85_RS10120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGX85_RS10125	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGX85_RS10130	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EGX85_RS10135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EGX85_RS10145	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EGX85_RS10150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EGX85_RS10155	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EGX85_RS10160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EGX85_RS10165	COG1841	ribosomal large subunit assembly
EGX85_RS10170	COG0200	Binds to the 23S rRNA
EGX85_RS10175	COG0201	protein transport
EGX85_RS10180	COG0563	adenylate kinase activity
EGX85_RS10185	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGX85_RS10190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX85_RS10195	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EGX85_RS10205	COG0202	RNA polymerase activity
EGX85_RS10210	COG0203	ribosomal protein L17
EGX85_RS10215	COG1122	ATPase activity
EGX85_RS10220	COG1122	ATPase activity
EGX85_RS10230	COG0101	tRNA pseudouridine synthase activity
EGX85_RS10235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EGX85_RS10240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGX85_RS10245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EGX85_RS10250	COG1349	DNA-binding transcription factor activity
EGX85_RS10260	COG0698	ribose 5-phosphate isomerase
EGX85_RS10265	COG0698	ribose 5-phosphate isomerase
EGX85_RS10270	COG1105	Belongs to the carbohydrate kinase PfkB family
EGX85_RS10275	COG3684	Belongs to the aldolase LacD family
EGX85_RS10280	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGX85_RS10285	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX85_RS10285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX85_RS10290	COG2723	6-phospho-beta-galactosidase activity
EGX85_RS10300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX85_RS10305	COG0604	alcohol dehydrogenase
EGX85_RS10310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX85_RS10325	COG1302	Protein conserved in bacteria
EGX85_RS10335	COG4264	IucA IucC family
EGX85_RS10340	COG2814	Major facilitator Superfamily
EGX85_RS10350	COG3457	Alanine racemase
EGX85_RS10355	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EGX85_RS10360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX85_RS10365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX85_RS10370	COG3314	Sporulation integral membrane protein YlbJ
EGX85_RS10375	COG2329	Antibiotic biosynthesis monooxygenase
EGX85_RS10385	COG1988	membrane-bound metal-dependent
EGX85_RS10390	COG4284	Utp--glucose-1-phosphate uridylyltransferase
EGX85_RS10395	COG1272	protein, Hemolysin III
EGX85_RS10410	COG2814	Major facilitator Superfamily
EGX85_RS10415	COG0489	protein tyrosine kinase activity
EGX85_RS10470	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EGX85_RS10480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGX85_RS10490	COG1119	ATPase activity
EGX85_RS10495	COG0561	phosphatase activity
EGX85_RS10520	COG0640	Transcriptional regulator
EGX85_RS10525	COG0702	epimerase
EGX85_RS10530	COG1482	cell wall glycoprotein biosynthetic process
EGX85_RS10550	COG0783	Belongs to the Dps family
EGX85_RS10555	COG0813	purine-nucleoside phosphorylase activity
EGX85_RS10560	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGX85_RS10565	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EGX85_RS10570	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EGX85_RS10580	COG1854	S-ribosylhomocysteine lyase activity
EGX85_RS10600	COG5146	pantothenate kinase activity
EGX85_RS10615	COG0504	CTP synthase activity
EGX85_RS10625	COG0191	fructose-bisphosphate aldolase activity
EGX85_RS10630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGX85_RS10640	COG1012	belongs to the aldehyde dehydrogenase family
EGX85_RS10645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGX85_RS10650	COG0254	rRNA binding
EGX85_RS10655	COG1435	thymidine kinase activity
EGX85_RS10660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EGX85_RS10665	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX85_RS10670	COG0009	L-threonylcarbamoyladenylate synthase
EGX85_RS10675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX85_RS10680	COG4475	Protein of unknown function (DUF436)
EGX85_RS10685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGX85_RS10690	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EGX85_RS10695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGX85_RS10705	COG0356	it plays a direct role in the translocation of protons across the membrane
EGX85_RS10710	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGX85_RS10715	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EGX85_RS10720	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGX85_RS10725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EGX85_RS10730	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EGX85_RS10735	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EGX85_RS10740	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EGX85_RS10750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGX85_RS10755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGX85_RS10765	COG0629	single-stranded DNA binding
EGX85_RS10770	COG1388	LysM domain
EGX85_RS10775	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EGX85_RS10785	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EGX85_RS10790	COG0352	thiamine-phosphate diphosphorylase activity
EGX85_RS10795	COG0706	membrane insertase activity
EGX85_RS10805	COG1418	mRNA catabolic process
EGX85_RS10810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX85_RS10815	COG1937	Protein conserved in bacteria
EGX85_RS10835	COG0772	Belongs to the SEDS family
EGX85_RS10840	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGX85_RS10845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGX85_RS10850	COG0513	Belongs to the DEAD box helicase family
EGX85_RS10860	COG3428	Bacterial PH domain
EGX85_RS10865	COG3402	PFAM membrane-flanked domain
EGX85_RS10870	COG0736	holo-[acyl-carrier-protein] synthase activity
EGX85_RS10875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGX85_RS10885	COG2337	Toxic component of a toxin-antitoxin (TA) module
EGX85_RS10890	COG2208	phosphoserine phosphatase activity
EGX85_RS10905	COG1191	sigma factor activity
EGX85_RS10910	COG2183	response to ionizing radiation
EGX85_RS10950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGX85_RS10955	COG0066	3-isopropylmalate dehydratase activity
EGX85_RS10960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGX85_RS10965	COG0473	3-isopropylmalate dehydrogenase activity
EGX85_RS10975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EGX85_RS10980	COG0440	acetolactate synthase activity
EGX85_RS10985	COG0028	Belongs to the TPP enzyme family
EGX85_RS10990	COG0129	dihydroxy-acid dehydratase activity
EGX85_RS10995	COG0802	atpase or kinase
EGX85_RS11000	COG1214	PFAM Peptidase M22, glycoprotease
EGX85_RS11005	COG0456	acetyltransferase
EGX85_RS11010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EGX85_RS11015	COG0488	(ABC) transporter
EGX85_RS11020	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EGX85_RS11025	COG2391	methyltransferase activity
EGX85_RS11030	COG0425	Belongs to the sulfur carrier protein TusA family
EGX85_RS11035	COG0004	ammonium transporteR
EGX85_RS11040	COG1609	Transcriptional regulator
EGX85_RS11045	COG1621	beta-fructofuranosidase activity
EGX85_RS11050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX85_RS11055	COG3279	Response regulator of the LytR AlgR family
EGX85_RS11070	COG4512	PFAM Accessory gene regulator B
EGX85_RS11095	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EGX85_RS11100	COG0459	protein refolding
EGX85_RS11105	COG0582	viral genome integration into host DNA
EGX85_RS11165	COG1725	Transcriptional regulator
EGX85_RS11180	COG1131	(ABC) transporter
EGX85_RS11220	COG2706	6-phosphogluconolactonase activity
EGX85_RS11225	COG1012	belongs to the aldehyde dehydrogenase family
EGX85_RS11230	COG1227	inorganic diphosphatase activity
EGX85_RS11235	COG1335	isochorismatase
EGX85_RS11245	COG1605	Chorismate mutase
EGX85_RS11245	COG0077	Prephenate dehydratase
EGX85_RS11255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EGX85_RS11260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGX85_RS11265	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EGX85_RS11275	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGX85_RS11280	COG4496	protein, YerC YecD
EGX85_RS11285	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EGX85_RS11290	COG0210	DNA helicase
EGX85_RS11295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGX85_RS11300	COG4851	CamS sex pheromone cAM373 precursor
EGX85_RS11310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX85_RS11315	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGX85_RS11320	COG0154	amidase activity
EGX85_RS11325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGX85_RS11330	COG1597	lipid kinase activity
EGX85_RS11335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGX85_RS11345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGX85_RS11355	COG1528	Iron-storage protein
EGX85_RS11370	COG4129	membrane
EGX85_RS11375	COG0024	Methionine aminopeptidase
EGX85_RS11380	COG4221	oxidoreductase activity
EGX85_RS11400	COG4585	Histidine kinase
EGX85_RS11405	COG2197	response regulator
EGX85_RS11410	COG1295	ribonuclease BN
EGX85_RS11420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX85_RS11425	COG4840	Belongs to the UPF0435 family
EGX85_RS11430	COG2309	aminopeptidase activity
EGX85_RS11435	COG1607	acyl-coa hydrolase
EGX85_RS11445	COG0535	radical SAM domain protein
EGX85_RS11455	COG0693	protein deglycase activity
EGX85_RS11460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX85_RS11465	COG2137	regulation of response to DNA damage stimulus
EGX85_RS11475	COG1134	teichoic acid transport
EGX85_RS11475	COG1388	LysM domain
EGX85_RS11485	COG1988	membrane-bound metal-dependent
EGX85_RS11490	COG1194	a g-specific adenine glycosylase
EGX85_RS11495	COG3557	Belongs to the UPF0374 family
EGX85_RS11505	COG4129	membrane
EGX85_RS11510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGX85_RS11515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGX85_RS11520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX85_RS11525	COG0735	belongs to the Fur family
EGX85_RS11695	COG1126	abc transporter atp-binding protein
EGX85_RS11700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGX85_RS11710	COG0363	glucosamine-6-phosphate deaminase activity
EGX85_RS11725	COG0114	fumarate hydratase activity
EGX85_RS11730	COG0564	pseudouridine synthase activity
EGX85_RS11735	COG4585	Histidine kinase
EGX85_RS11735	COG2203	Gaf domain
EGX85_RS11740	COG2197	response regulator
EGX85_RS11750	COG4399	Belongs to the UPF0754 family
EGX85_RS11755	COG3679	Belongs to the UPF0342 family
EGX85_RS11765	COG4717	serine-type aminopeptidase activity
EGX85_RS11770	COG3481	metal-dependent phosphohydrolase, HD sub domain
EGX85_RS11775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX85_RS11790	COG0537	adenosine 5'-monophosphoramidase activity
EGX85_RS11795	COG1131	(ABC) transporter
EGX85_RS11800	COG4473	ABC transporter
EGX85_RS11810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EGX85_RS11815	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGX85_RS11820	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EGX85_RS11870	COG0318	PFAM AMP-dependent synthetase and ligase
EGX85_RS11880	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EGX85_RS11885	COG0494	nUDIX hydrolase
EGX85_RS11890	COG1506	peptidase
EGX85_RS11895	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EGX85_RS11900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EGX85_RS11915	COG0656	L-ascorbic acid biosynthetic process
EGX85_RS11920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX85_RS11925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX85_RS11935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGX85_RS11960	COG4193	domain, Protein
EGX85_RS11960	COG3266	domain, Protein
EGX85_RS11960	COG5632	N-Acetylmuramoyl-L-alanine amidase
EGX85_RS11975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX85_RS11975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX85_RS11980	COG0307	riboflavin synthase, alpha
EGX85_RS11985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX85_RS11985	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX85_RS11990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EGX85_RS11995	COG0506	proline dehydrogenase activity
EGX85_RS12000	COG2267	carboxylic ester hydrolase activity
EGX85_RS12010	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EGX85_RS12015	COG1242	4 iron, 4 sulfur cluster binding
EGX85_RS12020	COG2814	Major facilitator Superfamily
EGX85_RS12025	COG0495	leucyl-tRNA aminoacylation
EGX85_RS12040	COG1196	nuclear chromosome segregation
EGX85_RS12040	COG1511	domain protein
EGX85_RS12040	COG4372	Transposase
EGX85_RS12050	COG2081	HI0933 family
EGX85_RS12055	COG2244	polysaccharide biosynthetic process
EGX85_RS12060	COG1187	pseudouridine synthase activity
EGX85_RS12070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGX85_RS12080	COG0510	thiamine kinase activity
EGX85_RS12085	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGX85_RS12090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX85_RS12100	COG1363	Peptidase, m42
EGX85_RS12110	COG4848	Belongs to the UPF0354 family
EGX85_RS12115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX85_RS12120	COG1674	ftsk spoiiie
EGX85_RS12125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGX85_RS12130	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EGX85_RS12140	COG1605	Chorismate mutase
EGX85_RS12140	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EGX85_RS12145	COG1609	Transcriptional regulator
EGX85_RS12155	COG0454	-acetyltransferase
EGX85_RS12160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGX85_RS12170	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EGX85_RS12180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGX85_RS12190	COG0477	Major facilitator Superfamily
EGX85_RS12195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX85_RS12200	COG0204	Acyl-transferase
EGX85_RS12205	COG1263	PTS System
EGX85_RS12205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX85_RS12225	COG1764	response to oxidative stress
EGX85_RS12230	COG0584	glycerophosphoryl diester phosphodiesterase
EGX85_RS12235	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGX85_RS12245	COG1956	GAF domain-containing protein
EGX85_RS12255	COG1104	cysteine desulfurase activity
EGX85_RS12260	COG0301	tRNA thio-modification
EGX85_RS12265	COG0730	response to heat
EGX85_RS12270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EGX85_RS12275	COG0827	DNA restriction-modification system
EGX85_RS12280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGX85_RS12285	COG0589	response to stress
EGX85_RS12290	COG0686	Belongs to the AlaDH PNT family
EGX85_RS12295	COG0006	proline dipeptidase activity
EGX85_RS12300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EGX85_RS12320	COG4109	DRTGG domain
EGX85_RS12325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EGX85_RS12330	COG0587	DNA-directed DNA polymerase activity
EGX85_RS12335	COG0281	malic enzyme
EGX85_RS12340	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EGX85_RS12345	COG0825	malonyl-CoA metabolic process
EGX85_RS12350	COG0205	6-phosphofructokinase activity
EGX85_RS12355	COG0469	pyruvate kinase activity
EGX85_RS12365	COG1113	amino acid transport
EGX85_RS12370	COG0372	Belongs to the citrate synthase family
EGX85_RS12375	COG0538	isocitrate dehydrogenase activity
EGX85_RS12390	COG0745	RESPONSE REGULATOR receiver
EGX85_RS12395	COG5002	protein histidine kinase activity
EGX85_RS12400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX85_RS12400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX85_RS12410	COG0237	dephospho-CoA kinase activity
EGX85_RS12415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGX85_RS12420	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EGX85_RS12430	COG1484	DNA-dependent DNA replication
EGX85_RS12435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EGX85_RS12440	COG0833	amino acid
EGX85_RS12445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EGX85_RS12450	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EGX85_RS12455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EGX85_RS12460	COG4112	unkown
EGX85_RS12470	COG0544	peptidyl-prolyl cis-trans isomerase activity
EGX85_RS12475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EGX85_RS12485	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EGX85_RS12490	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EGX85_RS12495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX85_RS12500	COG0181	hydroxymethylbilane synthase activity
EGX85_RS12515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGX85_RS12525	COG2818	Glycosylase
EGX85_RS12530	COG0525	valine-tRNA ligase activity
EGX85_RS12535	COG0285	dihydrofolate synthase activity
EGX85_RS12545	COG2003	Belongs to the UPF0758 family
EGX85_RS12570	COG1792	Involved in formation and maintenance of cell shape
EGX85_RS12580	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EGX85_RS12585	COG2868	ribosomal protein
EGX85_RS12590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EGX85_RS12595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGX85_RS12600	COG4492	Belongs to the UPF0735 family
EGX85_RS12605	COG0632	four-way junction helicase activity
EGX85_RS12610	COG2255	four-way junction helicase activity
EGX85_RS12615	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EGX85_RS12620	COG0343	queuine tRNA-ribosyltransferase activity
EGX85_RS12625	COG1862	Preprotein translocase
EGX85_RS12630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX85_RS12630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX85_RS12635	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGX85_RS12635	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EGX85_RS12640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX85_RS12645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX85_RS12650	COG1490	D-aminoacyl-tRNA deacylase activity
EGX85_RS12655	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX85_RS12660	COG0124	histidyl-tRNA synthetase
EGX85_RS12665	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EGX85_RS12675	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGX85_RS12680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGX85_RS12685	COG1959	2 iron, 2 sulfur cluster binding
EGX85_RS12690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX85_RS12695	COG1104	cysteine desulfurase activity
EGX85_RS12700	COG0482	sulfurtransferase activity
EGX85_RS12710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX85_RS12715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EGX85_RS12720	COG4472	Bacterial protein of unknown function (DUF965)
EGX85_RS12725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGX85_RS12730	COG3906	Belongs to the UPF0473 family
EGX85_RS12740	COG0826	peptidase U32
EGX85_RS12745	COG0826	peptidase U32
EGX85_RS12750	COG0572	uridine kinase
EGX85_RS12755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX85_RS12770	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGX85_RS12775	COG1984	allophanate hydrolase subunit 2
EGX85_RS12780	COG0511	ligase activity, forming carbon-carbon bonds
EGX85_RS12785	COG0439	Biotin carboxylase
EGX85_RS12790	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EGX85_RS12795	COG1914	H( )-stimulated, divalent metal cation uptake system
EGX85_RS12800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGX85_RS12805	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EGX85_RS12810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EGX85_RS12815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGX85_RS12820	COG1534	Rna-binding protein
EGX85_RS12825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EGX85_RS12830	COG1713	HD superfamily hydrolase involved in NAD metabolism
EGX85_RS12835	COG0799	negative regulation of ribosome biogenesis
EGX85_RS12840	COG2226	methyltransferase
EGX85_RS12845	COG1596	polysaccharide export
EGX85_RS12845	COG1555	photosystem II stabilization
EGX85_RS12850	COG2131	deaminase
EGX85_RS12855	COG2333	competence protein COMEC
EGX85_RS12855	COG0658	competence protein
EGX85_RS12860	COG1466	dna polymerase III delta subunit
EGX85_RS12870	COG0268	Binds directly to 16S ribosomal RNA
EGX85_RS12875	COG0481	GTPase activity
EGX85_RS12880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX85_RS12885	COG1420	regulation of RNA biosynthetic process
EGX85_RS12890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGX85_RS12895	COG0443	Heat shock 70 kDa protein
EGX85_RS12900	COG0484	heat shock protein binding
EGX85_RS12905	COG2264	protein methyltransferase activity
EGX85_RS12910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGX85_RS12915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGX85_RS12925	COG1030	water channel activity
EGX85_RS12930	COG4864	UPF0365 protein
EGX85_RS12940	COG1702	phosphate starvation-inducible protein PhoH
EGX85_RS12945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EGX85_RS12950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EGX85_RS12960	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGX85_RS12965	COG1381	Involved in DNA repair and RecF pathway recombination
EGX85_RS12970	COG0423	glycine-tRNA ligase activity
EGX85_RS12975	COG0517	IMP dehydrogenase activity
EGX85_RS12980	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EGX85_RS12990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGX85_RS12995	COG2384	SAM-dependent methyltransferase
EGX85_RS13000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGX85_RS13015	COG1121	(ABC) transporter
EGX85_RS13020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX85_RS13035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGX85_RS13040	COG0768	penicillin binding
EGX85_RS13045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGX85_RS13050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGX85_RS13060	COG4483	Protein conserved in bacteria
EGX85_RS13065	COG1940	carbohydrate kinase activity
EGX85_RS13070	COG0011	TIGRFAM Protein of
EGX85_RS13075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX85_RS13080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX85_RS13085	COG1459	type II secretion system
EGX85_RS13090	COG4537	Required for transformation and DNA binding
EGX85_RS13115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EGX85_RS13120	COG0404	The glycine cleavage system catalyzes the degradation of glycine