CWR44_RS09840 7d68229a01f0c7b3e42af1cb9bd3f467 420 Pfam PF11799 impB/mucB/samB family C-terminal domain 258 363 2.1E-12 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR44_RS09840 7d68229a01f0c7b3e42af1cb9bd3f467 420 Gene3D G3DSA:3.30.70.270 128 185 7.2E-11 T 28-03-2018 CWR44_RS09840 7d68229a01f0c7b3e42af1cb9bd3f467 420 Gene3D G3DSA:3.30.70.270 51 127 1.0E-11 T 28-03-2018 CWR44_RS09840 7d68229a01f0c7b3e42af1cb9bd3f467 420 Gene3D G3DSA:3.30.1490.100 262 370 4.4E-21 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR44_RS09840 7d68229a01f0c7b3e42af1cb9bd3f467 420 SUPERFAMILY SSF56672 10 249 2.05E-52 T 28-03-2018 CWR44_RS09840 7d68229a01f0c7b3e42af1cb9bd3f467 420 Gene3D G3DSA:1.10.150.20 186 261 6.5E-18 T 28-03-2018 CWR44_RS09840 7d68229a01f0c7b3e42af1cb9bd3f467 420 Pfam PF11798 IMS family HHH motif 183 213 1.2E-7 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CWR44_RS09840 7d68229a01f0c7b3e42af1cb9bd3f467 420 SUPERFAMILY SSF100879 270 355 1.2E-7 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR44_RS09840 7d68229a01f0c7b3e42af1cb9bd3f467 420 Pfam PF00817 impB/mucB/samB family 15 165 4.2E-32 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR44_RS01535 3556efdd008994601fa986226eb26c33 273 Pfam PF01226 Formate/nitrite transporter 24 262 1.5E-48 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CWR44_RS01535 3556efdd008994601fa986226eb26c33 273 Gene3D G3DSA:1.20.1080.10 10 273 2.4E-56 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWR44_RS05655 e9c48b4e74c7043d4248a5c0a9d8fcbf 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.3E-69 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CWR44_RS05655 e9c48b4e74c7043d4248a5c0a9d8fcbf 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 4.3E-67 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CWR44_RS05655 e9c48b4e74c7043d4248a5c0a9d8fcbf 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS05655 e9c48b4e74c7043d4248a5c0a9d8fcbf 156 Gene3D G3DSA:1.10.455.10 6 156 2.0E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CWR44_RS05655 e9c48b4e74c7043d4248a5c0a9d8fcbf 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.156 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CWR44_RS05655 e9c48b4e74c7043d4248a5c0a9d8fcbf 156 PIRSF PIRSF002122 3 156 2.1E-58 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CWR44_RS05655 e9c48b4e74c7043d4248a5c0a9d8fcbf 156 SUPERFAMILY SSF47973 4 149 7.59E-61 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CWR44_RS02545 a0da19fd8371a801475868b89f272b51 391 Pfam PF07687 Peptidase dimerisation domain 183 279 3.6E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS02545 a0da19fd8371a801475868b89f272b51 391 SUPERFAMILY SSF53187 4 199 8.17E-82 T 28-03-2018 CWR44_RS02545 a0da19fd8371a801475868b89f272b51 391 SUPERFAMILY SSF53187 300 390 8.17E-82 T 28-03-2018 CWR44_RS02545 a0da19fd8371a801475868b89f272b51 391 PIRSF PIRSF005962 1 391 9.4E-118 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS02545 a0da19fd8371a801475868b89f272b51 391 SUPERFAMILY SSF55031 186 298 7.98E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS02545 a0da19fd8371a801475868b89f272b51 391 Gene3D G3DSA:3.40.630.10 271 390 0.19 T 28-03-2018 CWR44_RS02545 a0da19fd8371a801475868b89f272b51 391 Gene3D G3DSA:3.40.630.10 1 270 2.6E-61 T 28-03-2018 CWR44_RS02545 a0da19fd8371a801475868b89f272b51 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 378 3.9E-108 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS02545 a0da19fd8371a801475868b89f272b51 391 Pfam PF01546 Peptidase family M20/M25/M40 74 384 3.0E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS09410 3ef920150471b346ba803aa2836cd548 82 Gene3D G3DSA:1.10.238.10 39 80 1.4E-4 T 28-03-2018 CWR44_RS09410 3ef920150471b346ba803aa2836cd548 82 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 5 66 1.0E-10 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CWR44_RS09410 3ef920150471b346ba803aa2836cd548 82 SUPERFAMILY SSF47473 39 78 4.35E-5 T 28-03-2018 IPR011992 EF-hand domain pair CWR44_RS09410 3ef920150471b346ba803aa2836cd548 82 Hamap MF_00363 UPF0154 protein . 6 76 23.081 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CWR44_RS09410 3ef920150471b346ba803aa2836cd548 82 Pfam PF03672 Uncharacterised protein family (UPF0154) 14 73 2.6E-31 T 28-03-2018 IPR005359 Protein with unknown function UPF0154 CWR44_RS01940 031bd848d03b04b4f2c595e9f87a784d 426 Gene3D G3DSA:1.20.1250.20 2 206 3.9E-43 T 28-03-2018 CWR44_RS01940 031bd848d03b04b4f2c595e9f87a784d 426 Gene3D G3DSA:1.20.1250.20 221 426 9.7E-27 T 28-03-2018 CWR44_RS01940 031bd848d03b04b4f2c595e9f87a784d 426 Pfam PF07690 Major Facilitator Superfamily 18 378 5.0E-65 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS01940 031bd848d03b04b4f2c595e9f87a784d 426 SUPERFAMILY SSF103473 4 415 2.88E-84 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01940 031bd848d03b04b4f2c595e9f87a784d 426 PIRSF PIRSF002808 1 424 1.9E-39 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CWR44_RS10175 037d979a7aca6ca95f41876fa5de1609 292 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 175 255 8.4E-28 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CWR44_RS10175 037d979a7aca6ca95f41876fa5de1609 292 Gene3D G3DSA:3.40.50.1010 3 187 6.7E-61 T 28-03-2018 IPR029060 PIN domain-like CWR44_RS10175 037d979a7aca6ca95f41876fa5de1609 292 SUPERFAMILY SSF47807 174 269 5.53E-29 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CWR44_RS10175 037d979a7aca6ca95f41876fa5de1609 292 Gene3D G3DSA:1.10.150.20 188 264 1.3E-26 T 28-03-2018 CWR44_RS10175 037d979a7aca6ca95f41876fa5de1609 292 SMART SM00475 3 263 5.3E-113 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CWR44_RS10175 037d979a7aca6ca95f41876fa5de1609 292 SUPERFAMILY SSF88723 3 156 1.94E-49 T 28-03-2018 IPR029060 PIN domain-like CWR44_RS10175 037d979a7aca6ca95f41876fa5de1609 292 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 161 4.5E-51 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CWR44_RS10175 037d979a7aca6ca95f41876fa5de1609 292 SMART SM00279 176 211 9.4E-16 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 Pfam PF02817 e3 binding domain 127 161 2.6E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 SUPERFAMILY SSF51230 3 93 6.67E-26 T 28-03-2018 IPR011053 Single hybrid motif CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 Gene3D G3DSA:2.40.50.100 47 124 3.7E-9 T 28-03-2018 CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 Gene3D G3DSA:3.90.1170.30 2 46 1.3E-12 T 28-03-2018 CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 SUPERFAMILY SSF52777 197 431 3.25E-87 T 28-03-2018 CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 Gene3D G3DSA:3.30.559.10 185 431 9.3E-91 T 28-03-2018 CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 203 431 4.9E-89 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 Gene3D G3DSA:4.10.320.10 125 182 1.2E-20 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 Pfam PF00364 Biotin-requiring enzyme 4 76 4.5E-24 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CWR44_RS07995 94a204404c01601ae113d85f9a0c3498 433 SUPERFAMILY SSF47005 121 166 5.49E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS01465 63a0d236905525f8659000fafd88ef67 147 Gene3D G3DSA:1.10.10.10 6 129 1.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01465 63a0d236905525f8659000fafd88ef67 147 SUPERFAMILY SSF46785 6 141 2.03E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01465 63a0d236905525f8659000fafd88ef67 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 7.5E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS01465 63a0d236905525f8659000fafd88ef67 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 7.5E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS01465 63a0d236905525f8659000fafd88ef67 147 Pfam PF01047 MarR family 36 93 3.8E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS01465 63a0d236905525f8659000fafd88ef67 147 SMART SM00347 29 127 6.1E-22 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 PIRSF PIRSF000149 1 335 1.3E-116 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 2.5E-35 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 266 281 7.2E-32 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 7.2E-32 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 7.2E-32 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 7.2E-32 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 7.2E-32 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 Gene3D G3DSA:3.30.360.10 161 315 9.5E-61 T 28-03-2018 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 Gene3D G3DSA:3.40.50.720 1 160 1.3E-71 T 28-03-2018 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 SUPERFAMILY SSF55347 150 313 5.69E-63 T 28-03-2018 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 SMART SM00846 3 151 8.0E-85 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 313 1.1E-60 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 2.1E-131 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06925 3a2a16e696e5ad17aaa560319674005f 335 SUPERFAMILY SSF51735 1 150 4.55E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS05835 eddf095090c8d43f73f49cfba2997e17 292 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 14 286 1.6E-51 T 28-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CWR44_RS05835 eddf095090c8d43f73f49cfba2997e17 292 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 33 291 31.745 T 28-03-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CWR44_RS05835 eddf095090c8d43f73f49cfba2997e17 292 Pfam PF02649 Type I GTP cyclohydrolase folE2 33 286 9.4E-72 T 28-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CWR44_RS05835 eddf095090c8d43f73f49cfba2997e17 292 Gene3D G3DSA:3.10.270.10 32 289 6.7E-84 T 28-03-2018 CWR44_RS07935 76f99f94c29bec5de62a9f8e2a31f2fa 77 SUPERFAMILY SSF52833 3 63 1.92E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS07935 76f99f94c29bec5de62a9f8e2a31f2fa 77 Gene3D G3DSA:3.40.30.10 2 75 8.2E-10 T 28-03-2018 CWR44_RS07935 76f99f94c29bec5de62a9f8e2a31f2fa 77 Pfam PF00462 Glutaredoxin 5 59 1.4E-9 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CWR44_RS00880 ba6a80c2eaf84c656c10a0cd5e2e81ef 340 SUPERFAMILY SSF102114 6 308 3.4E-82 T 28-03-2018 CWR44_RS00880 ba6a80c2eaf84c656c10a0cd5e2e81ef 340 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 340 41.227 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CWR44_RS00880 ba6a80c2eaf84c656c10a0cd5e2e81ef 340 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 340 2.8E-119 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CWR44_RS00880 ba6a80c2eaf84c656c10a0cd5e2e81ef 340 SMART SM00729 14 222 4.4E-9 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR44_RS00880 ba6a80c2eaf84c656c10a0cd5e2e81ef 340 Pfam PF13353 4Fe-4S single cluster domain 22 128 3.4E-8 T 28-03-2018 CWR44_RS00880 ba6a80c2eaf84c656c10a0cd5e2e81ef 340 Pfam PF04055 Radical SAM superfamily 18 182 2.2E-26 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS00880 ba6a80c2eaf84c656c10a0cd5e2e81ef 340 Pfam PF06463 Molybdenum Cofactor Synthesis C 189 317 1.7E-36 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CWR44_RS00880 ba6a80c2eaf84c656c10a0cd5e2e81ef 340 Gene3D G3DSA:3.20.20.70 1 340 1.6E-83 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS00880 ba6a80c2eaf84c656c10a0cd5e2e81ef 340 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CWR44_RS09855 32348565335f10287fd0c7709c841891 469 Gene3D G3DSA:3.60.120.10 4 468 1.9E-130 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CWR44_RS09855 32348565335f10287fd0c7709c841891 469 Pfam PF00425 chorismate binding enzyme 201 460 5.2E-84 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CWR44_RS09855 32348565335f10287fd0c7709c841891 469 SUPERFAMILY SSF56322 8 467 1.31E-127 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CWR44_RS09855 32348565335f10287fd0c7709c841891 469 Pfam PF04715 Anthranilate synthase component I, N terminal region 16 151 5.7E-27 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS09855 32348565335f10287fd0c7709c841891 469 PRINTS PR00095 Anthranilate synthase component I signature 417 431 4.1E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS09855 32348565335f10287fd0c7709c841891 469 PRINTS PR00095 Anthranilate synthase component I signature 402 416 4.1E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS09855 32348565335f10287fd0c7709c841891 469 PRINTS PR00095 Anthranilate synthase component I signature 322 335 4.1E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS09855 32348565335f10287fd0c7709c841891 469 PRINTS PR00095 Anthranilate synthase component I signature 308 321 4.1E-19 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 SUPERFAMILY SSF58113 1206 1360 5.49E-5 T 28-03-2018 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Gene3D G3DSA:3.90.20.10 3 104 1.1E-5 T 28-03-2018 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Gene3D G3DSA:1.20.5.50 105 224 0.23 T 28-03-2018 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 SUPERFAMILY SSF51261 1644 1764 3.4E-25 T 28-03-2018 IPR011055 Duplicated hybrid motif CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Gene3D G3DSA:1.20.120.20 683 920 4.3E-6 T 28-03-2018 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Gene3D G3DSA:1.20.120.20 1241 1364 1.5E-16 T 28-03-2018 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 SUPERFAMILY SSF53955 1777 1875 3.94E-8 T 28-03-2018 IPR023346 Lysozyme-like domain CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Gene3D G3DSA:1.20.120.20 1072 1240 4.7E-13 T 28-03-2018 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Pfam PF01551 Peptidase family M23 1663 1759 2.9E-17 T 28-03-2018 IPR016047 Peptidase M23 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Gene3D G3DSA:1.10.530.10 1776 1904 9.0E-10 T 28-03-2018 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Gene3D G3DSA:2.70.70.10 1654 1775 4.5E-24 T 28-03-2018 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Gene3D G3DSA:1.20.5.1230 932 1061 0.011 T 28-03-2018 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Gene3D G3DSA:1.20.5.1230 1446 1653 7.3E-7 T 28-03-2018 CWR44_RS09710 14ae50478fff36e94f077796527d77ca 2006 Gene3D G3DSA:1.20.1480.30 233 343 0.12 T 28-03-2018 CWR44_RS06255 33d6388638f518b519ac36ed563bbe8b 722 Gene3D G3DSA:3.90.550.10 1 276 5.1E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS06255 33d6388638f518b519ac36ed563bbe8b 722 Pfam PF00535 Glycosyl transferase family 2 5 128 1.8E-31 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR44_RS06255 33d6388638f518b519ac36ed563bbe8b 722 SUPERFAMILY SSF53756 462 647 1.73E-14 T 28-03-2018 CWR44_RS06255 33d6388638f518b519ac36ed563bbe8b 722 SUPERFAMILY SSF53448 3 205 4.07E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS06255 33d6388638f518b519ac36ed563bbe8b 722 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 349 715 1.1E-127 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CWR44_RS02270 91c415144872ba8a20b3313ad049fa63 332 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 197 219 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CWR44_RS02270 91c415144872ba8a20b3313ad049fa63 332 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CWR44_RS02270 91c415144872ba8a20b3313ad049fa63 332 SUPERFAMILY SSF52283 1 136 3.19E-36 T 28-03-2018 CWR44_RS02270 91c415144872ba8a20b3313ad049fa63 332 Gene3D G3DSA:3.40.50.720 118 303 4.9E-45 T 28-03-2018 CWR44_RS02270 91c415144872ba8a20b3313ad049fa63 332 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 177 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CWR44_RS02270 91c415144872ba8a20b3313ad049fa63 332 Gene3D G3DSA:3.40.50.720 2 117 8.8E-22 T 28-03-2018 CWR44_RS02270 91c415144872ba8a20b3313ad049fa63 332 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 332 1.9E-29 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CWR44_RS02270 91c415144872ba8a20b3313ad049fa63 332 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 300 8.0E-48 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWR44_RS02270 91c415144872ba8a20b3313ad049fa63 332 SUPERFAMILY SSF51735 103 302 6.53E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS05300 502f437e90301709b39932bf2ef89f71 87 Gene3D G3DSA:2.30.30.100 2 76 1.1E-32 T 28-03-2018 CWR44_RS05300 502f437e90301709b39932bf2ef89f71 87 Pfam PF06257 Biofilm formation stimulator VEG 4 74 1.5E-31 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CWR44_RS05300 502f437e90301709b39932bf2ef89f71 87 PIRSF PIRSF037257 1 85 1.2E-37 T 28-03-2018 IPR009366 Protein Veg GO:0042710 CWR44_RS08760 022e04f5098386cede4c8669329932b2 116 ProSitePatterns PS01319 Ribosome-binding factor A signature. 74 95 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CWR44_RS08760 022e04f5098386cede4c8669329932b2 116 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 95 1.0E-45 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWR44_RS08760 022e04f5098386cede4c8669329932b2 116 Gene3D G3DSA:3.30.300.20 3 115 6.9E-36 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWR44_RS08760 022e04f5098386cede4c8669329932b2 116 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 115 24.812 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWR44_RS08760 022e04f5098386cede4c8669329932b2 116 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 113 8.5E-39 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWR44_RS08760 022e04f5098386cede4c8669329932b2 116 SUPERFAMILY SSF89919 1 111 5.23E-37 T 28-03-2018 IPR023799 Ribosome-binding factor A domain CWR44_RS08760 022e04f5098386cede4c8669329932b2 116 Pfam PF02033 Ribosome-binding factor A 5 108 5.5E-34 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 80 90 - T 28-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 Gene3D G3DSA:3.40.50.1170 1 205 7.2E-53 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 Pfam PF00710 Asparaginase, N-terminal 3 191 4.4E-56 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 SUPERFAMILY SSF53774 1 322 7.85E-98 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 PIRSF PIRSF001220 1 324 7.7E-90 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 Gene3D G3DSA:3.40.50.40 206 322 9.7E-27 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 6.3E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 PRINTS PR00139 Asparaginase/glutaminase family signature 252 270 6.3E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 PRINTS PR00139 Asparaginase/glutaminase family signature 79 97 6.3E-15 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 SMART SM00870 3 317 1.8E-132 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 PIRSF PIRSF500176 1 324 1.5E-87 T 28-03-2018 CWR44_RS10350 db801df420f37550ae7209d81ed1cf22 324 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 28-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 64 3.8E-7 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 96 122 0.0073 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 333 9.0E-15 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 SUPERFAMILY SSF52540 549 856 3.8E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 857 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Gene3D G3DSA:3.40.50.300 156 341 7.3E-27 T 28-03-2018 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Gene3D G3DSA:3.40.50.300 555 770 3.4E-53 T 28-03-2018 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 SMART SM00382 197 341 7.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 SMART SM00382 600 746 2.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 SUPERFAMILY SSF81923 4 154 1.08E-27 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 8.6E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 8.6E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 8.6E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 8.6E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 SUPERFAMILY SSF52540 157 548 4.07E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 293 305 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Pfam PF07724 AAA domain (Cdc48 subfamily) 599 765 1.2E-55 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 771 851 6.3E-23 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Gene3D G3DSA:1.10.8.60 342 464 2.9E-39 T 28-03-2018 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Gene3D G3DSA:1.10.8.60 465 550 6.8E-6 T 28-03-2018 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Gene3D G3DSA:1.10.8.60 771 866 1.3E-22 T 28-03-2018 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 Gene3D G3DSA:1.10.1780.10 1 149 5.7E-18 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR44_RS07445 b4e52a264c691c8b073dac6b0d69933b 869 SMART SM01086 771 861 4.4E-30 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWR44_RS07560 9874263b4c924391d744ac9364981514 461 Gene3D G3DSA:3.10.580.10 135 277 5.4E-22 T 28-03-2018 CWR44_RS07560 9874263b4c924391d744ac9364981514 461 SMART SM00924 40 145 1.2E-27 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CWR44_RS07560 9874263b4c924391d744ac9364981514 461 SUPERFAMILY SSF158791 19 142 2.09E-27 T 28-03-2018 CWR44_RS07560 9874263b4c924391d744ac9364981514 461 Pfam PF00571 CBS domain 209 263 4.7E-9 T 28-03-2018 IPR000644 CBS domain CWR44_RS07560 9874263b4c924391d744ac9364981514 461 Pfam PF00571 CBS domain 146 203 5.0E-7 T 28-03-2018 IPR000644 CBS domain CWR44_RS07560 9874263b4c924391d744ac9364981514 461 SUPERFAMILY SSF161093 285 457 7.06E-51 T 28-03-2018 CWR44_RS07560 9874263b4c924391d744ac9364981514 461 SUPERFAMILY SSF54631 144 281 3.41E-33 T 28-03-2018 CWR44_RS07560 9874263b4c924391d744ac9364981514 461 Gene3D G3DSA:1.10.357.20 285 460 5.6E-40 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CWR44_RS07560 9874263b4c924391d744ac9364981514 461 Pfam PF03448 MgtE intracellular N domain 40 143 1.3E-23 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CWR44_RS07560 9874263b4c924391d744ac9364981514 461 Gene3D G3DSA:1.25.60.10 7 134 3.4E-23 T 28-03-2018 CWR44_RS07560 9874263b4c924391d744ac9364981514 461 TIGRFAM TIGR00400 mgtE: magnesium transporter 22 458 5.7E-121 T 28-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CWR44_RS07560 9874263b4c924391d744ac9364981514 461 Pfam PF01769 Divalent cation transporter 329 450 1.3E-29 T 28-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CWR44_RS07560 9874263b4c924391d744ac9364981514 461 SMART SM00116 216 264 7.8E-7 T 28-03-2018 IPR000644 CBS domain CWR44_RS07560 9874263b4c924391d744ac9364981514 461 SMART SM00116 152 205 7.6 T 28-03-2018 IPR000644 CBS domain CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Gene3D G3DSA:3.30.230.70 315 558 1.6E-59 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 SUPERFAMILY SSF50249 624 699 1.86E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 PIRSF PIRSF005499 2 700 1.9E-295 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 SUPERFAMILY SSF54211 8 144 6.07E-49 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Gene3D G3DSA:2.40.50.140 631 700 1.8E-22 T 28-03-2018 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 SMART SM00316 624 694 1.3E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 1.8E-15 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Pfam PF03725 3' exoribonuclease family, domain 2 463 532 1.5E-8 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Pfam PF00013 KH domain 560 618 1.4E-8 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Gene3D G3DSA:1.10.10.400 249 314 2.1E-16 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 11 695 0.0 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 697 30.754 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 SUPERFAMILY SSF54791 559 644 1.1E-21 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Pfam PF00575 S1 RNA binding domain 623 693 9.0E-19 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 SUPERFAMILY SSF55666 145 236 2.49E-27 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 SUPERFAMILY SSF54211 297 491 7.59E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 SUPERFAMILY SSF55666 454 552 6.28E-30 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Gene3D G3DSA:3.30.230.70 12 248 2.0E-56 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 SUPERFAMILY SSF46915 239 324 1.7E-14 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 324 1.3E-11 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 SMART SM00322 556 621 1.9E-10 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Pfam PF01138 3' exoribonuclease family, domain 1 327 460 5.6E-17 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 3.5E-22 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CWR44_RS08780 ac8fae8cdcc38394972e09c43dbffc77 700 Gene3D G3DSA:3.30.1370.10 559 630 1.3E-12 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 37.88 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 PIRSF PIRSF002162 1 177 9.1E-50 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 Gene3D G3DSA:3.90.930.12 5 85 2.9E-30 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 SUPERFAMILY SSF56053 1 82 1.08E-26 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 SUPERFAMILY SSF56053 83 177 2.73E-35 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 Gene3D G3DSA:3.90.930.12 86 178 4.8E-40 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 6.3E-75 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.7E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.7E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.7E-34 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 Pfam PF00347 Ribosomal protein L6 90 164 6.3E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00720 2fb006e4001d142264baf1cd6b827a6f 178 Pfam PF00347 Ribosomal protein L6 11 82 4.3E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 ProSitePatterns PS01176 Initiation factor 2 signature. 669 691 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 220 377 2.5E-39 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Gene3D G3DSA:3.40.50.300 215 389 3.1E-40 T 28-03-2018 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Gene3D G3DSA:2.40.30.10 619 716 3.2E-31 T 28-03-2018 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 SUPERFAMILY SSF52156 495 625 1.83E-38 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Pfam PF11987 Translation-initiation factor 2 504 608 3.8E-37 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Pfam PF00009 Elongation factor Tu GTP binding domain 223 377 9.2E-36 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Gene3D G3DSA:3.40.50.10050 516 597 3.6E-27 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Gene3D G3DSA:3.30.56.50 143 184 2.2E-9 T 28-03-2018 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Gene3D G3DSA:3.30.56.50 4 46 2.6E-14 T 28-03-2018 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 SUPERFAMILY SSF52540 210 390 5.1E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Gene3D G3DSA:2.40.30.10 390 483 6.9E-15 T 28-03-2018 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 133 716 4.0E-271 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 716 17.36 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 141 191 7.7E-15 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 52 1.5E-16 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 SUPERFAMILY SSF50447 390 472 3.53E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWR44_RS08755 aa90c8d414ae7c6106f5663eaa064358 716 SUPERFAMILY SSF50447 619 716 1.64E-34 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 559 2.1E-230 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 SUPERFAMILY SSF52954 459 565 7.36E-27 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 SUPERFAMILY SSF55681 403 473 8.3E-99 T 28-03-2018 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 SUPERFAMILY SSF55681 10 237 8.3E-99 T 28-03-2018 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 455 2.7E-56 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 Pfam PF03129 Anticodon binding domain 474 558 1.1E-16 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 Gene3D G3DSA:3.40.50.800 457 566 2.5E-27 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 Gene3D G3DSA:3.30.930.10 11 456 1.5E-94 T 28-03-2018 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.5E-19 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.5E-19 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.5E-19 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.5E-19 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 Pfam PF04073 Aminoacyl-tRNA editing domain 257 372 4.2E-26 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 SUPERFAMILY SSF55826 218 385 8.89E-32 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR44_RS08725 2f843a5c0819f7c310d4aa38b082510e 566 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 564 40.009 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 SUPERFAMILY SSF51735 2 191 3.45E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 SMART SM00984 308 400 9.9E-27 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 285 2.3E-23 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 Gene3D G3DSA:3.40.50.720 222 410 2.0E-53 T 28-03-2018 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 396 5.1E-136 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 Gene3D G3DSA:1.20.5.170 198 221 7.3E-12 T 28-03-2018 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 SUPERFAMILY SSF52413 296 400 2.88E-25 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 SUPERFAMILY SSF48179 198 291 4.25E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 PIRSF PIRSF000124 1 411 8.1E-76 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 309 399 9.6E-23 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 178 4.1E-57 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 Gene3D G3DSA:3.40.50.720 1 196 3.6E-44 T 28-03-2018 CWR44_RS02690 5681c85eea692db72a23844752f8c0e2 423 PIRSF PIRSF500136 1 416 8.0E-156 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 SUPERFAMILY SSF56091 3 311 9.25E-121 T 28-03-2018 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Gene3D G3DSA:1.10.150.20 545 608 2.6E-5 T 28-03-2018 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Pfam PF14520 Helix-hairpin-helix domain 438 494 2.6E-4 T 28-03-2018 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 112 141 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Hamap MF_01588 DNA ligase [ligA]. 2 662 51.308 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 PIRSF PIRSF001604 1 666 4.2E-249 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 SUPERFAMILY SSF47781 397 576 3.71E-59 T 28-03-2018 IPR010994 RuvA domain 2-like CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Gene3D G3DSA:1.10.287.610 2 66 2.1E-22 T 28-03-2018 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 SMART SM00278 472 491 92.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 SMART SM00278 536 555 120.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 SMART SM00278 438 457 42.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 11 658 5.3E-262 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 315 390 6.4E-33 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 324 339 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 SUPERFAMILY SSF52113 589 660 2.43E-17 T 28-03-2018 IPR001357 BRCT domain CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 SMART SM00292 588 663 8.5E-8 T 28-03-2018 IPR001357 BRCT domain CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Gene3D G3DSA:2.40.50.140 315 382 5.2E-31 T 28-03-2018 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 SMART SM00532 3 440 6.5E-271 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Pfam PF12826 Helix-hairpin-helix motif 503 565 1.2E-20 T 28-03-2018 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Gene3D G3DSA:1.10.150.20 495 544 6.3E-16 T 28-03-2018 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Gene3D G3DSA:3.30.1490.70 232 314 3.2E-28 T 28-03-2018 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 590 659 3.7E-13 T 28-03-2018 IPR001357 BRCT domain CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 400 426 2.4E-10 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Gene3D G3DSA:1.10.150.20 424 494 6.1E-28 T 28-03-2018 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Gene3D G3DSA:3.40.50.10190 609 661 1.9E-15 T 28-03-2018 IPR001357 BRCT domain CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 4 311 3.1E-129 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 SUPERFAMILY SSF50249 310 393 1.63E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS12405 8a957456ea7822d44619e927b1006928 667 Gene3D G3DSA:3.30.470.30 116 231 1.5E-47 T 28-03-2018 CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 Gene3D G3DSA:1.10.8.60 359 455 2.4E-29 T 28-03-2018 CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 8 467 6.7E-190 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 SUPERFAMILY SSF52540 209 462 2.18E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 SUPERFAMILY SSF52540 8 143 2.18E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 SMART SM00382 53 356 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 Gene3D G3DSA:3.40.50.300 5 356 3.1E-46 T 28-03-2018 CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 SMART SM01086 359 455 3.0E-22 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 Pfam PF07724 AAA domain (Cdc48 subfamily) 221 353 2.1E-35 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 Pfam PF07724 AAA domain (Cdc48 subfamily) 56 133 1.8E-6 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 5 467 41.948 T 28-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CWR44_RS08680 a1cfe6e3e27359d4a878b3044030eb2d 467 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 359 433 1.3E-6 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWR44_RS11715 cbd1344c8205f5645af1575dddd31023 333 SUPERFAMILY SSF51730 36 302 3.18E-67 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CWR44_RS11715 cbd1344c8205f5645af1575dddd31023 333 Gene3D G3DSA:3.20.20.220 10 313 1.2E-59 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CWR44_RS11715 cbd1344c8205f5645af1575dddd31023 333 Pfam PF01619 Proline dehydrogenase 44 290 4.1E-30 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CWR44_RS11715 cbd1344c8205f5645af1575dddd31023 333 PIRSF PIRSF000196 1 306 5.5E-124 T 28-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CWR44_RS02985 f91445b379b3ddbc4a3c7e3656b3f949 502 SUPERFAMILY SSF53756 161 500 1.52E-36 T 28-03-2018 CWR44_RS02985 f91445b379b3ddbc4a3c7e3656b3f949 502 TIGRFAM TIGR02918 TIGR02918: accessory Sec system glycosylation protein GtfA 1 499 4.8E-250 T 28-03-2018 IPR014267 Glycosyltransferase Gtf1 GO:0016757 CWR44_RS02985 f91445b379b3ddbc4a3c7e3656b3f949 502 Hamap MF_01472 Glycosyltransferase Gtf1 [gtf1]. 2 501 47.849 T 28-03-2018 IPR014267 Glycosyltransferase Gtf1 GO:0016757 CWR44_RS02985 f91445b379b3ddbc4a3c7e3656b3f949 502 Pfam PF00534 Glycosyl transferases group 1 318 451 7.8E-23 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWR44_RS02985 f91445b379b3ddbc4a3c7e3656b3f949 502 Gene3D G3DSA:3.40.50.2000 307 476 7.3E-26 T 28-03-2018 CWR44_RS06200 7bbb82d8696f70b36e1b6756c30479bc 215 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 60 8.2E-24 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CWR44_RS06200 7bbb82d8696f70b36e1b6756c30479bc 215 Gene3D G3DSA:2.30.30.90 124 214 3.8E-8 T 28-03-2018 CWR44_RS06200 7bbb82d8696f70b36e1b6756c30479bc 215 SUPERFAMILY SSF47979 63 135 2.22E-24 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CWR44_RS06200 7bbb82d8696f70b36e1b6756c30479bc 215 Gene3D G3DSA:1.10.60.10 73 123 5.4E-23 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CWR44_RS06200 7bbb82d8696f70b36e1b6756c30479bc 215 SUPERFAMILY SSF46785 2 62 3.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06200 7bbb82d8696f70b36e1b6756c30479bc 215 Gene3D G3DSA:1.10.10.10 2 70 7.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06200 7bbb82d8696f70b36e1b6756c30479bc 215 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 131 7.5E-26 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CWR44_RS06200 7bbb82d8696f70b36e1b6756c30479bc 215 SMART SM00899 142 214 3.0E-5 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR44_RS06200 7bbb82d8696f70b36e1b6756c30479bc 215 Pfam PF04023 FeoA domain 143 212 3.8E-7 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR44_RS06200 7bbb82d8696f70b36e1b6756c30479bc 215 SMART SM00529 24 123 2.9E-45 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 Gene3D G3DSA:3.30.1490.20 129 201 2.1E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 8.8E-82 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 SMART SM00878 336 442 2.5E-59 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 Pfam PF02785 Biotin carboxylase C-terminal domain 336 443 4.2E-37 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 SUPERFAMILY SSF52440 1 112 3.81E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.6E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 Gene3D G3DSA:3.30.470.20 203 445 9.3E-100 T 28-03-2018 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 SUPERFAMILY SSF56059 82 350 7.78E-73 T 28-03-2018 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 Gene3D G3DSA:3.40.50.20 1 128 2.1E-48 T 28-03-2018 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 447 4.4E-221 T 28-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CWR44_RS10555 eae92f126b8330f11627a119d22e69ca 451 SUPERFAMILY SSF51246 331 444 5.23E-44 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CWR44_RS00520 878e75943ca116a6bffcadaf897ce10e 343 SUPERFAMILY SSF81345 16 338 3.4E-81 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWR44_RS00520 878e75943ca116a6bffcadaf897ce10e 343 Pfam PF01032 FecCD transport family 31 338 2.9E-94 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR44_RS00520 878e75943ca116a6bffcadaf897ce10e 343 Gene3D G3DSA:1.10.3470.10 15 342 2.9E-65 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS00105 e6464bc12a77420ec7aa1edbba66cf79 229 SUPERFAMILY SSF48613 3 226 1.67E-51 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CWR44_RS00105 e6464bc12a77420ec7aa1edbba66cf79 229 Pfam PF03070 TENA/THI-4/PQQC family 10 216 5.6E-44 T 28-03-2018 IPR004305 Thiaminase-2/PQQC CWR44_RS00105 e6464bc12a77420ec7aa1edbba66cf79 229 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 216 2.1E-70 T 28-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 CWR44_RS00105 e6464bc12a77420ec7aa1edbba66cf79 229 Gene3D G3DSA:1.20.910.10 1 225 8.8E-33 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CWR44_RS06270 79ed528e4b7026ccdf786a5b450a74a3 265 Gene3D G3DSA:3.40.50.300 1 238 1.5E-62 T 28-03-2018 CWR44_RS06270 79ed528e4b7026ccdf786a5b450a74a3 265 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS06270 79ed528e4b7026ccdf786a5b450a74a3 265 SUPERFAMILY SSF52540 4 230 1.05E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06270 79ed528e4b7026ccdf786a5b450a74a3 265 SMART SM00382 28 217 3.1E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS06270 79ed528e4b7026ccdf786a5b450a74a3 265 Pfam PF00005 ABC transporter 20 167 1.9E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 SMART SM00490 493 577 1.0E-22 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 Pfam PF17191 RecG wedge domain 15 172 6.0E-20 T 28-03-2018 IPR033454 RecG, wedge domain CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 Gene3D G3DSA:2.40.50.140 57 147 2.8E-8 T 28-03-2018 CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 Pfam PF00270 DEAD/DEAH box helicase 263 419 5.1E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 SUPERFAMILY SSF52540 440 648 1.1E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 Gene3D G3DSA:1.10.150.20 11 56 1.8E-4 T 28-03-2018 CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 30 652 8.9E-230 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 SMART SM00487 258 447 1.8E-32 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 Pfam PF00271 Helicase conserved C-terminal domain 465 576 2.0E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 Gene3D G3DSA:3.40.50.300 244 444 2.5E-35 T 28-03-2018 CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 SUPERFAMILY SSF52540 178 440 2.91E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 Gene3D G3DSA:3.40.50.300 445 617 4.8E-35 T 28-03-2018 CWR44_RS08545 dc1ee76964dc369ab9aa121afeff8fb3 683 SUPERFAMILY SSF50249 10 175 5.48E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 Gene3D G3DSA:3.50.30.10 394 534 2.7E-41 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 SUPERFAMILY SSF56059 1 378 1.14E-139 T 28-03-2018 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 SUPERFAMILY SSF51621 512 869 1.36E-116 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 450 461 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 3 869 0.0 T 28-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 PIRSF PIRSF000853 1 875 0.0 T 28-03-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 Gene3D G3DSA:3.20.20.60 535 873 1.2E-101 T 28-03-2018 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 760 778 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 Gene3D G3DSA:1.10.189.10 341 389 9.7E-20 T 28-03-2018 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 517 868 2.1E-80 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 SUPERFAMILY SSF52009 393 512 1.96E-34 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 Gene3D G3DSA:3.30.470.20 243 340 1.1E-22 T 28-03-2018 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 Pfam PF00391 PEP-utilising enzyme, mobile domain 422 503 1.7E-26 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 Gene3D G3DSA:1.20.80.30 117 197 5.2E-30 T 28-03-2018 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 57 292 2.8E-32 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 302 353 2.9E-11 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CWR44_RS02500 5e5c5ef9492dadb2c9063d5958405fed 875 Gene3D G3DSA:3.30.1490.20 2 116 8.6E-31 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR44_RS10425 3d55a365a3d75004d3ad90f9b08ce8ea 180 Gene3D G3DSA:3.90.79.10 3 180 8.1E-41 T 28-03-2018 CWR44_RS10425 3d55a365a3d75004d3ad90f9b08ce8ea 180 Pfam PF00293 NUDIX domain 43 161 6.9E-19 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR44_RS10425 3d55a365a3d75004d3ad90f9b08ce8ea 180 ProSitePatterns PS00893 Nudix box signature. 76 97 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWR44_RS10425 3d55a365a3d75004d3ad90f9b08ce8ea 180 SUPERFAMILY SSF55811 6 176 2.44E-48 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR44_RS09010 a9f265a6fcd097b63061c2a552daf60f 142 Gene3D G3DSA:2.40.50.140 1 122 1.6E-42 T 28-03-2018 CWR44_RS09010 a9f265a6fcd097b63061c2a552daf60f 142 Pfam PF00436 Single-strand binding protein family 2 103 6.9E-38 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWR44_RS09010 a9f265a6fcd097b63061c2a552daf60f 142 SUPERFAMILY SSF50249 1 142 1.3E-51 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS09010 a9f265a6fcd097b63061c2a552daf60f 142 PIRSF PIRSF002070 1 141 3.2E-41 T 28-03-2018 CWR44_RS09010 a9f265a6fcd097b63061c2a552daf60f 142 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 120 1.6E-41 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWR44_RS09010 a9f265a6fcd097b63061c2a552daf60f 142 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 35.331 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWR44_RS12655 48ccfc186e9dad637e69731d23b8126c 238 Gene3D G3DSA:3.40.50.2300 1 136 4.2E-13 T 28-03-2018 CWR44_RS12655 48ccfc186e9dad637e69731d23b8126c 238 SMART SM00850 149 237 7.8E-12 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR44_RS12655 48ccfc186e9dad637e69731d23b8126c 238 Pfam PF04397 LytTr DNA-binding domain 151 237 6.6E-19 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR44_RS12655 48ccfc186e9dad637e69731d23b8126c 238 Gene3D G3DSA:2.40.50.40 139 208 7.5E-14 T 28-03-2018 CWR44_RS12655 48ccfc186e9dad637e69731d23b8126c 238 Pfam PF00072 Response regulator receiver domain 3 120 4.9E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS12655 48ccfc186e9dad637e69731d23b8126c 238 SMART SM00448 1 120 2.0E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS12655 48ccfc186e9dad637e69731d23b8126c 238 SUPERFAMILY SSF52172 1 133 4.98E-12 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS12260 c4b1830e02cbbef7df72077a47cdbd5c 381 Gene3D G3DSA:3.20.20.70 20 372 1.7E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS12260 c4b1830e02cbbef7df72077a47cdbd5c 381 SUPERFAMILY SSF102114 33 331 7.72E-25 T 28-03-2018 CWR44_RS12260 c4b1830e02cbbef7df72077a47cdbd5c 381 Pfam PF04055 Radical SAM superfamily 37 185 6.6E-11 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS12260 c4b1830e02cbbef7df72077a47cdbd5c 381 Pfam PF08756 YfkB-like domain 221 371 7.4E-77 T 28-03-2018 IPR014866 YfkB-like domain CWR44_RS12260 c4b1830e02cbbef7df72077a47cdbd5c 381 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 9 371 7.9E-188 T 28-03-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB CWR44_RS12260 c4b1830e02cbbef7df72077a47cdbd5c 381 Pfam PF13353 4Fe-4S single cluster domain 42 111 2.6E-5 T 28-03-2018 CWR44_RS03925 43e2bf336a61ee6b553e1aa957029c48 407 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 67 76 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR44_RS03925 43e2bf336a61ee6b553e1aa957029c48 407 SUPERFAMILY SSF53187 4 176 2.31E-56 T 28-03-2018 CWR44_RS03925 43e2bf336a61ee6b553e1aa957029c48 407 SUPERFAMILY SSF53187 317 403 2.31E-56 T 28-03-2018 CWR44_RS03925 43e2bf336a61ee6b553e1aa957029c48 407 Gene3D G3DSA:3.40.630.10 3 303 8.8E-59 T 28-03-2018 CWR44_RS03925 43e2bf336a61ee6b553e1aa957029c48 407 SUPERFAMILY SSF55031 176 222 6.13E-16 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS03925 43e2bf336a61ee6b553e1aa957029c48 407 SUPERFAMILY SSF55031 251 302 6.13E-16 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS03925 43e2bf336a61ee6b553e1aa957029c48 407 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 103 142 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR44_RS03925 43e2bf336a61ee6b553e1aa957029c48 407 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 10 395 8.1E-86 T 28-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CWR44_RS03925 43e2bf336a61ee6b553e1aa957029c48 407 Pfam PF01546 Peptidase family M20/M25/M40 69 400 2.3E-38 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS03925 43e2bf336a61ee6b553e1aa957029c48 407 Pfam PF07687 Peptidase dimerisation domain 173 304 1.5E-22 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS05210 4c20531854bf071293a285b9964fffb3 198 SMART SM00278 12 31 0.0049 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS05210 4c20531854bf071293a285b9964fffb3 198 Pfam PF13662 Toprim domain 80 171 3.7E-26 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS05210 4c20531854bf071293a285b9964fffb3 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 2.3E-88 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CWR44_RS05210 4c20531854bf071293a285b9964fffb3 198 SMART SM00493 80 165 1.3E-14 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS05210 4c20531854bf071293a285b9964fffb3 198 Gene3D G3DSA:3.40.1360.10 77 170 3.4E-39 T 28-03-2018 CWR44_RS05210 4c20531854bf071293a285b9964fffb3 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 109.789 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CWR44_RS05210 4c20531854bf071293a285b9964fffb3 198 Gene3D G3DSA:1.10.150.20 8 38 0.0011 T 28-03-2018 CWR44_RS05210 4c20531854bf071293a285b9964fffb3 198 Pfam PF02132 RecR protein 40 78 2.0E-16 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CWR44_RS05210 4c20531854bf071293a285b9964fffb3 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CWR44_RS05210 4c20531854bf071293a285b9964fffb3 198 SUPERFAMILY SSF111304 1 198 1.96E-78 T 28-03-2018 IPR023627 Recombination protein RecR CWR44_RS10180 e1e3642c05248831fa407f45d113d334 1147 SUPERFAMILY SSF52540 25 288 1.42E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10180 e1e3642c05248831fa407f45d113d334 1147 Pfam PF00350 Dynamin family 45 195 1.1E-23 T 28-03-2018 IPR022812 Dynamin superfamily CWR44_RS10180 e1e3642c05248831fa407f45d113d334 1147 Pfam PF00350 Dynamin family 593 808 3.6E-34 T 28-03-2018 IPR022812 Dynamin superfamily CWR44_RS10180 e1e3642c05248831fa407f45d113d334 1147 Gene3D G3DSA:3.40.50.300 569 1022 4.1E-31 T 28-03-2018 CWR44_RS10180 e1e3642c05248831fa407f45d113d334 1147 Gene3D G3DSA:3.40.50.300 10 564 1.7E-25 T 28-03-2018 CWR44_RS10180 e1e3642c05248831fa407f45d113d334 1147 SUPERFAMILY SSF52540 724 881 3.59E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10180 e1e3642c05248831fa407f45d113d334 1147 SUPERFAMILY SSF52540 575 643 3.59E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03490 c8ed8c65f63944ef96f7fcb31ebda90d 398 SUPERFAMILY SSF53383 36 397 7.07E-84 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS03490 c8ed8c65f63944ef96f7fcb31ebda90d 398 Gene3D G3DSA:3.90.1150.10 1 89 3.9E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS03490 c8ed8c65f63944ef96f7fcb31ebda90d 398 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 5 397 1.5E-103 T 28-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CWR44_RS03490 c8ed8c65f63944ef96f7fcb31ebda90d 398 Pfam PF00155 Aminotransferase class I and II 47 384 6.1E-33 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR44_RS03490 c8ed8c65f63944ef96f7fcb31ebda90d 398 Gene3D G3DSA:3.40.640.10 90 290 3.5E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS03490 c8ed8c65f63944ef96f7fcb31ebda90d 398 Gene3D G3DSA:3.90.1150.10 291 396 1.6E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS00615 9a6704571ac51d279c0700423a877ef2 142 PIRSF PIRSF005384 1 142 4.2E-42 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR44_RS00615 9a6704571ac51d279c0700423a877ef2 142 TIGRFAM TIGR01118 lacA: galactose-6-phosphate isomerase, LacA subunit 1 141 7.0E-82 T 28-03-2018 IPR004783 Galactose-6-phosphate isomerase subunit LacA GO:0005990|GO:0050044 KEGG: 00052+5.3.1.26 CWR44_RS00615 9a6704571ac51d279c0700423a877ef2 142 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 140 1.3E-33 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR44_RS00615 9a6704571ac51d279c0700423a877ef2 142 Pfam PF02502 Ribose/Galactose Isomerase 3 138 6.8E-39 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR44_RS00615 9a6704571ac51d279c0700423a877ef2 142 Gene3D G3DSA:3.40.1400.10 1 142 2.3E-40 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR44_RS00615 9a6704571ac51d279c0700423a877ef2 142 Hamap MF_01555 Galactose-6-phosphate isomerase subunit LacA [lacA]. 1 142 41.087 T 28-03-2018 IPR004783 Galactose-6-phosphate isomerase subunit LacA GO:0005990|GO:0050044 KEGG: 00052+5.3.1.26 CWR44_RS00615 9a6704571ac51d279c0700423a877ef2 142 SUPERFAMILY SSF89623 1 141 4.58E-44 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR44_RS03355 05a32879fd9af293e6868590598833f8 134 SUPERFAMILY SSF47413 4 69 1.97E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS03355 05a32879fd9af293e6868590598833f8 134 SMART SM00530 9 64 1.7E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS03355 05a32879fd9af293e6868590598833f8 134 Pfam PF05154 TM2 domain 73 120 7.9E-16 T 28-03-2018 IPR007829 TM2 domain CWR44_RS03355 05a32879fd9af293e6868590598833f8 134 Pfam PF01381 Helix-turn-helix 10 62 6.7E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS03355 05a32879fd9af293e6868590598833f8 134 Gene3D G3DSA:1.10.260.40 1 100 2.4E-21 T 28-03-2018 CWR44_RS00505 e5304cc8df58f4c951df70df81aace33 104 SUPERFAMILY SSF54909 1 100 6.52E-24 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CWR44_RS00505 e5304cc8df58f4c951df70df81aace33 104 Hamap MF_01272 Heme oxygenase (staphylobilin-producing) [isdG]. 1 104 28.308 T 28-03-2018 IPR023953 Heme oxygenase IsdG GO:0004392|GO:0033212|GO:0055114 CWR44_RS00505 e5304cc8df58f4c951df70df81aace33 104 Gene3D G3DSA:3.30.70.100 1 104 4.5E-19 T 28-03-2018 CWR44_RS00505 e5304cc8df58f4c951df70df81aace33 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 1.4E-14 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CWR44_RS00395 5951c746dd74a9c799cb0d1f6d3d2d6e 601 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 601 2.8E-226 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CWR44_RS00395 5951c746dd74a9c799cb0d1f6d3d2d6e 601 SUPERFAMILY SSF53697 245 601 1.07E-93 T 28-03-2018 CWR44_RS00395 5951c746dd74a9c799cb0d1f6d3d2d6e 601 Gene3D G3DSA:3.40.50.10490 240 453 8.7E-58 T 28-03-2018 CWR44_RS00395 5951c746dd74a9c799cb0d1f6d3d2d6e 601 Gene3D G3DSA:3.60.20.10 2 239 9.7E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS00395 5951c746dd74a9c799cb0d1f6d3d2d6e 601 SUPERFAMILY SSF56235 2 234 2.49E-68 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS00395 5951c746dd74a9c799cb0d1f6d3d2d6e 601 Pfam PF01380 SIS domain 461 583 7.3E-17 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR44_RS00395 5951c746dd74a9c799cb0d1f6d3d2d6e 601 Pfam PF01380 SIS domain 289 413 5.3E-32 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR44_RS00395 5951c746dd74a9c799cb0d1f6d3d2d6e 601 Pfam PF13522 Glutamine amidotransferase domain 64 192 6.8E-21 T 28-03-2018 CWR44_RS00395 5951c746dd74a9c799cb0d1f6d3d2d6e 601 Gene3D G3DSA:3.40.50.10490 454 599 1.0E-39 T 28-03-2018 CWR44_RS00395 5951c746dd74a9c799cb0d1f6d3d2d6e 601 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 601 38.454 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CWR44_RS11370 089cc4f8049b57bee844296086df853e 409 Pfam PF03949 Malic enzyme, NAD binding domain 162 383 2.8E-24 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CWR44_RS11370 089cc4f8049b57bee844296086df853e 409 SMART SM00919 160 384 1.7E-124 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CWR44_RS11370 089cc4f8049b57bee844296086df853e 409 SUPERFAMILY SSF51735 160 402 8.51E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS11370 089cc4f8049b57bee844296086df853e 409 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 28-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CWR44_RS11370 089cc4f8049b57bee844296086df853e 409 Pfam PF00390 Malic enzyme, N-terminal domain 16 148 6.6E-30 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CWR44_RS11370 089cc4f8049b57bee844296086df853e 409 Gene3D G3DSA:3.40.50.720 158 406 3.4E-83 T 28-03-2018 CWR44_RS11370 089cc4f8049b57bee844296086df853e 409 SMART SM01274 15 148 7.2E-80 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CWR44_RS11370 089cc4f8049b57bee844296086df853e 409 PIRSF PIRSF000106 29 406 1.6E-86 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CWR44_RS11370 089cc4f8049b57bee844296086df853e 409 Gene3D G3DSA:3.40.50.10380 3 157 7.1E-42 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CWR44_RS11370 089cc4f8049b57bee844296086df853e 409 SUPERFAMILY SSF53223 7 158 3.45E-55 T 28-03-2018 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 Pfam PF00476 DNA polymerase family A 500 874 3.8E-154 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 3 168 8.6E-53 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 Gene3D G3DSA:3.30.420.10 305 491 2.1E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 SMART SM00279 173 208 1.8E-16 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 SMART SM00482 633 840 1.7E-110 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 ProSitePatterns PS00447 DNA polymerase family A signature. 702 721 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 SUPERFAMILY SSF47807 170 269 7.18E-31 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 Gene3D G3DSA:1.20.1060.10 492 603 2.4E-33 T 28-03-2018 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 172 265 1.5E-33 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 SMART SM00474 287 467 1.0E-8 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 SMART SM00475 2 262 1.1E-139 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 SUPERFAMILY SSF53098 312 467 3.04E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 SUPERFAMILY SSF88723 2 168 4.58E-51 T 28-03-2018 IPR029060 PIN domain-like CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 TIGRFAM TIGR00593 pola: DNA polymerase I 4 876 0.0 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 Gene3D G3DSA:3.30.70.370 604 694 8.4E-15 T 28-03-2018 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 Gene3D G3DSA:3.30.70.370 702 876 2.4E-53 T 28-03-2018 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 Gene3D G3DSA:1.10.150.20 185 263 5.0E-30 T 28-03-2018 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 SUPERFAMILY SSF56672 471 876 1.67E-152 T 28-03-2018 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 Pfam PF01612 3'-5' exonuclease 319 443 2.0E-5 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 Gene3D G3DSA:3.40.50.1010 2 184 1.0E-64 T 28-03-2018 IPR029060 PIN domain-like CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 702 727 7.1E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 678 691 7.1E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 823 836 7.1E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 648 671 7.1E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 602 624 7.1E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 625 640 7.1E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 739 750 7.1E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 761 772 7.1E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11315 8ce565243bd3a657680db0a5dfb56172 876 PRINTS PR00868 DNA-polymerase family A (pol I) signature 793 809 7.1E-81 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 Gene3D G3DSA:1.10.530.10 1743 1891 3.3E-8 T 28-03-2018 CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 322 666 7.7E-99 T 28-03-2018 IPR010090 Phage tail tape measure protein CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 Gene3D G3DSA:1.10.287.620 154 282 1.9E-4 T 28-03-2018 CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 Gene3D G3DSA:1.20.120.20 1157 1286 2.2E-10 T 28-03-2018 CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 Gene3D G3DSA:2.70.70.10 1612 1742 8.2E-28 T 28-03-2018 CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 Pfam PF01551 Peptidase family M23 1636 1735 3.6E-21 T 28-03-2018 IPR016047 Peptidase M23 CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 Gene3D G3DSA:1.20.120.330 4 153 5.0E-5 T 28-03-2018 CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 Gene3D G3DSA:1.20.1000.10 575 1143 2.5E-4 T 28-03-2018 CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 Gene3D G3DSA:1.20.120.20 1444 1611 7.9E-7 T 28-03-2018 CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 SUPERFAMILY SSF53955 1779 1863 3.09E-5 T 28-03-2018 IPR023346 Lysozyme-like domain CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 SUPERFAMILY SSF51261 1603 1740 8.37E-32 T 28-03-2018 IPR011055 Duplicated hybrid motif CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 Pfam PF10145 Phage-related minor tail protein 362 560 5.4E-48 T 28-03-2018 IPR010090 Phage tail tape measure protein CWR44_RS09175 32031b8702d991451c8f6ecf6b40d9d1 1982 Gene3D G3DSA:1.10.287.700 1287 1380 1.4E-7 T 28-03-2018 CWR44_RS01650 1e1d78224aa3aa79bb708190226bbd61 160 Pfam PF14526 Integron-associated effector binding protein 7 158 4.8E-21 T 28-03-2018 IPR029441 Integron-associated effector binding protein CWR44_RS01650 1e1d78224aa3aa79bb708190226bbd61 160 SUPERFAMILY SSF55136 4 159 6.98E-23 T 28-03-2018 CWR44_RS01650 1e1d78224aa3aa79bb708190226bbd61 160 Gene3D G3DSA:3.20.80.10 2 160 1.9E-34 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CWR44_RS01650 1e1d78224aa3aa79bb708190226bbd61 160 SMART SM00871 3 159 1.0E-23 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR44_RS02765 bf4b3699bf2d13bd194290bb58e7d2c0 33 ProDom PD610536 SE2200 SAV2627.1 SA2420.1 MW2548 1 33 9.0E-5 T 28-03-2018 IPR022561 Protein of unknown function DUF2648 CWR44_RS02765 bf4b3699bf2d13bd194290bb58e7d2c0 33 Pfam PF10855 Protein of unknown function (DUF2648) 1 33 2.4E-12 T 28-03-2018 IPR022561 Protein of unknown function DUF2648 CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 SMART SM01086 311 405 2.4E-30 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 SMART SM00994 10 49 8.9E-22 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 3 405 1.1E-199 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 SUPERFAMILY SSF52540 59 394 2.92E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.0E-18 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 3.2E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 SMART SM00382 109 262 1.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 409 51.559 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 Gene3D G3DSA:3.40.50.300 53 309 1.9E-70 T 28-03-2018 CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 2.3E-16 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 SUPERFAMILY SSF57716 11 46 5.7E-11 T 28-03-2018 CWR44_RS11240 1bb0e4621a39f4e6eeaceffe62ca3663 420 Gene3D G3DSA:1.10.8.60 311 403 1.2E-31 T 28-03-2018 CWR44_RS03315 e90215adee406571c8ab09e284145d63 304 Gene3D G3DSA:3.40.50.1220 25 303 8.6E-14 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS03315 e90215adee406571c8ab09e284145d63 304 SUPERFAMILY SSF52467 23 297 5.14E-38 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS05885 5f4e9b9f2b6307c13b1ee15f01bc65f3 276 Gene3D G3DSA:3.40.1190.20 1 276 3.8E-52 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS05885 5f4e9b9f2b6307c13b1ee15f01bc65f3 276 SUPERFAMILY SSF53613 4 265 2.18E-66 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS05885 5f4e9b9f2b6307c13b1ee15f01bc65f3 276 Pfam PF08543 Phosphomethylpyrimidine kinase 13 259 6.5E-77 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CWR44_RS05885 5f4e9b9f2b6307c13b1ee15f01bc65f3 276 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 260 5.1E-71 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS06145 f98e1f8fbc0f37878afd7bb892bb7076 800 Pfam PF00361 Proton-conducting membrane transporter 129 422 1.4E-64 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS06145 f98e1f8fbc0f37878afd7bb892bb7076 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 1.2E-39 T 28-03-2018 CWR44_RS06145 f98e1f8fbc0f37878afd7bb892bb7076 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 1.2E-39 T 28-03-2018 CWR44_RS06145 f98e1f8fbc0f37878afd7bb892bb7076 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 153 174 1.2E-39 T 28-03-2018 CWR44_RS06145 f98e1f8fbc0f37878afd7bb892bb7076 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 1.2E-39 T 28-03-2018 CWR44_RS06145 f98e1f8fbc0f37878afd7bb892bb7076 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 106 126 1.2E-39 T 28-03-2018 CWR44_RS06145 f98e1f8fbc0f37878afd7bb892bb7076 800 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 1.2E-39 T 28-03-2018 CWR44_RS06145 f98e1f8fbc0f37878afd7bb892bb7076 800 Pfam PF13244 Domain of unknown function (DUF4040) 636 699 2.9E-20 T 28-03-2018 IPR025383 Domain of unknown function DUF4040 CWR44_RS06145 f98e1f8fbc0f37878afd7bb892bb7076 800 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 64 116 1.8E-9 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS08935 89380da145ac7bf7aa4ff913cf7b822a 158 PIRSF PIRSF000303 1 158 9.5E-69 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CWR44_RS08935 89380da145ac7bf7aa4ff913cf7b822a 158 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CWR44_RS08935 89380da145ac7bf7aa4ff913cf7b822a 158 Gene3D G3DSA:3.40.30.10 2 158 1.3E-49 T 28-03-2018 CWR44_RS08935 89380da145ac7bf7aa4ff913cf7b822a 158 PRINTS PR01011 Glutathione peroxidase family signature 22 39 2.4E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CWR44_RS08935 89380da145ac7bf7aa4ff913cf7b822a 158 PRINTS PR01011 Glutathione peroxidase family signature 57 73 2.4E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CWR44_RS08935 89380da145ac7bf7aa4ff913cf7b822a 158 PRINTS PR01011 Glutathione peroxidase family signature 122 131 2.4E-21 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CWR44_RS08935 89380da145ac7bf7aa4ff913cf7b822a 158 Pfam PF00255 Glutathione peroxidase 4 110 4.7E-41 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CWR44_RS08935 89380da145ac7bf7aa4ff913cf7b822a 158 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CWR44_RS08935 89380da145ac7bf7aa4ff913cf7b822a 158 SUPERFAMILY SSF52833 3 158 6.12E-62 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS05925 49d8ed6218be1d5d2e276a445c23d4f9 329 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 324 7.9E-117 T 28-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR44_RS05925 49d8ed6218be1d5d2e276a445c23d4f9 329 Pfam PF01515 Phosphate acetyl/butaryl transferase 4 324 3.9E-119 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR44_RS05925 49d8ed6218be1d5d2e276a445c23d4f9 329 PIRSF PIRSF000428 1 329 4.2E-107 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR44_RS05925 49d8ed6218be1d5d2e276a445c23d4f9 329 Gene3D G3DSA:3.40.50.10750 142 300 7.9E-62 T 28-03-2018 CWR44_RS05925 49d8ed6218be1d5d2e276a445c23d4f9 329 SUPERFAMILY SSF53659 5 326 1.32E-87 T 28-03-2018 CWR44_RS05295 6b50da66f78ff5376d04fe2ff80c6a16 296 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 53 80 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CWR44_RS05295 6b50da66f78ff5376d04fe2ff80c6a16 296 SUPERFAMILY SSF53335 20 290 3.19E-76 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS05295 6b50da66f78ff5376d04fe2ff80c6a16 296 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 21 286 3.7E-84 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CWR44_RS05295 6b50da66f78ff5376d04fe2ff80c6a16 296 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 21 289 53.929 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CWR44_RS05295 6b50da66f78ff5376d04fe2ff80c6a16 296 Gene3D G3DSA:1.10.8.100 227 290 2.9E-24 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CWR44_RS05295 6b50da66f78ff5376d04fe2ff80c6a16 296 Pfam PF00398 Ribosomal RNA adenine dimethylase 21 288 7.5E-71 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CWR44_RS05295 6b50da66f78ff5376d04fe2ff80c6a16 296 SMART SM00650 37 213 1.1E-80 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CWR44_RS05295 6b50da66f78ff5376d04fe2ff80c6a16 296 Gene3D G3DSA:3.40.50.150 3 226 5.3E-54 T 28-03-2018 CWR44_RS06855 ecc780cb9e11f4d07d0a1eee77e26180 159 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 106 141 7.3E-11 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS06855 ecc780cb9e11f4d07d0a1eee77e26180 159 SUPERFAMILY SSF51161 29 157 9.15E-34 T 28-03-2018 IPR011004 Trimeric LpxA-like CWR44_RS06855 ecc780cb9e11f4d07d0a1eee77e26180 159 Gene3D G3DSA:2.160.10.10 39 159 1.3E-29 T 28-03-2018 CWR44_RS11325 073037400e99b6eb91b741cdfa2e50fd 236 Gene3D G3DSA:3.40.50.2300 2 128 3.9E-37 T 28-03-2018 CWR44_RS11325 073037400e99b6eb91b741cdfa2e50fd 236 SMART SM00448 3 114 1.2E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS11325 073037400e99b6eb91b741cdfa2e50fd 236 Gene3D G3DSA:1.10.10.10 129 236 7.7E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11325 073037400e99b6eb91b741cdfa2e50fd 236 Pfam PF00072 Response regulator receiver domain 5 114 1.0E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS11325 073037400e99b6eb91b741cdfa2e50fd 236 SUPERFAMILY SSF46894 131 232 2.13E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS11325 073037400e99b6eb91b741cdfa2e50fd 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 231 1.5E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS11325 073037400e99b6eb91b741cdfa2e50fd 236 SMART SM00862 155 231 5.0E-31 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS11325 073037400e99b6eb91b741cdfa2e50fd 236 SUPERFAMILY SSF52172 2 127 8.4E-43 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS03385 ec84fc19d9a3bd23d0339fe637beac97 112 Pfam PF01381 Helix-turn-helix 7 61 7.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS03385 ec84fc19d9a3bd23d0339fe637beac97 112 SUPERFAMILY SSF47413 1 67 3.49E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS03385 ec84fc19d9a3bd23d0339fe637beac97 112 Gene3D G3DSA:1.10.260.40 1 91 1.4E-21 T 28-03-2018 CWR44_RS03385 ec84fc19d9a3bd23d0339fe637beac97 112 SMART SM00530 6 61 2.3E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 Pfam PF00391 PEP-utilising enzyme, mobile domain 508 576 6.8E-14 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 Pfam PF00224 Pyruvate kinase, barrel domain 1 342 4.2E-150 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 PRINTS PR01050 Pyruvate kinase family signature 269 293 2.2E-75 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 PRINTS PR01050 Pyruvate kinase family signature 244 268 2.2E-75 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 PRINTS PR01050 Pyruvate kinase family signature 186 200 2.2E-75 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 PRINTS PR01050 Pyruvate kinase family signature 294 312 2.2E-75 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 PRINTS PR01050 Pyruvate kinase family signature 217 243 2.2E-75 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 PRINTS PR01050 Pyruvate kinase family signature 313 329 2.2E-75 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 PRINTS PR01050 Pyruvate kinase family signature 59 75 2.2E-75 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 Gene3D G3DSA:2.40.33.10 85 156 2.5E-27 T 28-03-2018 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 473 1.7E-185 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 SUPERFAMILY SSF52935 323 474 5.63E-42 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 Gene3D G3DSA:3.20.20.60 1 84 6.8E-22 T 28-03-2018 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 Gene3D G3DSA:3.20.20.60 157 321 5.3E-64 T 28-03-2018 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 SUPERFAMILY SSF51621 1 74 2.62E-102 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 SUPERFAMILY SSF51621 156 343 2.62E-102 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 SUPERFAMILY SSF50800 70 167 5.58E-25 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 Gene3D G3DSA:3.50.30.10 472 580 9.5E-21 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 Pfam PF02887 Pyruvate kinase, alpha/beta domain 359 471 2.1E-36 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 Gene3D G3DSA:3.40.1380.20 322 471 5.6E-53 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CWR44_RS11350 96d8b250dcc1ccce09d1ab78ca5da7ed 586 SUPERFAMILY SSF52009 466 583 4.06E-21 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 TIGRFAM TIGR01529 argR_whole: arginine repressor 7 150 5.9E-50 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 PRINTS PR01467 Bacterial arginine repressor signature 38 53 3.7E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 PRINTS PR01467 Bacterial arginine repressor signature 89 102 3.7E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 PRINTS PR01467 Bacterial arginine repressor signature 22 35 3.7E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 PRINTS PR01467 Bacterial arginine repressor signature 119 134 3.7E-24 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 Gene3D G3DSA:3.30.1360.40 75 146 4.0E-27 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 SUPERFAMILY SSF55252 80 150 8.24E-22 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 88 150 6.0E-17 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 Gene3D G3DSA:1.10.10.10 4 67 1.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 SUPERFAMILY SSF46785 1 71 2.72E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 Pfam PF01316 Arginine repressor, DNA binding domain 2 70 1.5E-27 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 Hamap MF_00173 Arginine repressor [argR]. 1 150 67.715 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWR44_RS10525 fa16cc6ebd921577583149e86fb43fd7 150 Pfam PF02863 Arginine repressor, C-terminal domain 82 146 5.6E-25 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWR44_RS04870 17135401263f3d3a365ab28aa07ff6fd 189 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 158 179 1.9E-4 T 28-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CWR44_RS04870 17135401263f3d3a365ab28aa07ff6fd 189 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 189 4.1E-98 T 28-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CWR44_RS04870 17135401263f3d3a365ab28aa07ff6fd 189 PIRSF PIRSF000239 1 189 1.8E-48 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CWR44_RS04870 17135401263f3d3a365ab28aa07ff6fd 189 SUPERFAMILY SSF52833 4 188 1.86E-51 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS04870 17135401263f3d3a365ab28aa07ff6fd 189 Pfam PF00578 AhpC/TSA family 19 135 3.6E-33 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CWR44_RS04870 17135401263f3d3a365ab28aa07ff6fd 189 Gene3D G3DSA:3.40.30.10 11 156 2.2E-32 T 28-03-2018 CWR44_RS04870 17135401263f3d3a365ab28aa07ff6fd 189 Gene3D G3DSA:3.30.1020.10 157 184 7.4E-6 T 28-03-2018 CWR44_RS06695 b2bfc35bafeee110fa25918c4098b01c 322 SUPERFAMILY SSF47240 2 318 2.61E-78 T 28-03-2018 IPR009078 Ferritin-like superfamily CWR44_RS06695 b2bfc35bafeee110fa25918c4098b01c 322 Gene3D G3DSA:1.10.620.20 3 293 5.8E-64 T 28-03-2018 CWR44_RS06695 b2bfc35bafeee110fa25918c4098b01c 322 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 1 320 9.3E-126 T 28-03-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS06695 b2bfc35bafeee110fa25918c4098b01c 322 Pfam PF00268 Ribonucleotide reductase, small chain 5 281 2.0E-66 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 SUPERFAMILY SSF51064 153 208 3.14E-17 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 Hamap MF_01151 Protein GrpE [grpE]. 3 208 20.81 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 Gene3D G3DSA:3.90.20.20 2 151 8.0E-23 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 Gene3D G3DSA:2.30.22.10 152 208 2.5E-20 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 ProSitePatterns PS01071 grpE protein signature. 163 206 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 PRINTS PR00773 GrpE protein signature 187 206 7.1E-31 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 PRINTS PR00773 GrpE protein signature 106 121 7.1E-31 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 PRINTS PR00773 GrpE protein signature 160 175 7.1E-31 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 PRINTS PR00773 GrpE protein signature 78 94 7.1E-31 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 SUPERFAMILY SSF58014 56 152 2.35E-25 T 28-03-2018 CWR44_RS10830 b55f83e7c4354948a4afa0372580891a 208 Pfam PF01025 GrpE 46 208 3.8E-49 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 193 421 2.8E-78 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 Gene3D G3DSA:3.30.559.10 177 421 1.9E-83 T 28-03-2018 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 Pfam PF00364 Biotin-requiring enzyme 3 74 3.7E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 Pfam PF02817 e3 binding domain 128 160 5.5E-9 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 Gene3D G3DSA:4.10.320.10 118 176 1.2E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 SUPERFAMILY SSF52777 194 421 2.4E-80 T 28-03-2018 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 422 1.5E-178 T 28-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 SUPERFAMILY SSF47005 121 163 7.19E-7 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 Gene3D G3DSA:3.90.1170.30 44 96 0.007 T 28-03-2018 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 Gene3D G3DSA:3.90.1170.30 1 43 5.9E-16 T 28-03-2018 CWR44_RS10060 df72459fab3040ad5369bfe4c25a1041 423 SUPERFAMILY SSF51230 2 93 1.01E-26 T 28-03-2018 IPR011053 Single hybrid motif CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 1 144 1.1E-63 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 130 146 1.3E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 193 202 1.3E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 149 162 1.3E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 84 95 1.3E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 109 127 1.3E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 165 178 1.3E-45 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 SUPERFAMILY SSF52096 3 312 1.09E-98 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 1 314 1.1E-148 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 312 49.488 T 28-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11360 e66c87b7f44533441d438a0075ccc6bd 315 Gene3D G3DSA:3.90.226.10 7 308 1.3E-66 T 28-03-2018 CWR44_RS05535 2f15958b39995d9a099199e84781d987 335 ProSitePatterns PS00112 Phosphagen kinase active site signature. 156 162 - T 28-03-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 CWR44_RS05535 2f15958b39995d9a099199e84781d987 335 Gene3D G3DSA:3.30.590.10 2 244 2.7E-73 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CWR44_RS05535 2f15958b39995d9a099199e84781d987 335 Hamap MF_00602 Protein-arginine kinase [mcsB]. 10 335 35.057 T 28-03-2018 IPR023660 Protein arginine kinase GO:0006950|GO:0016775 CWR44_RS05535 2f15958b39995d9a099199e84781d987 335 SUPERFAMILY SSF55931 5 254 7.85E-78 T 28-03-2018 CWR44_RS05535 2f15958b39995d9a099199e84781d987 335 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 60 242 5.6E-68 T 28-03-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 CWR44_RS08340 4acf6d2dba01ea446adc9fb2782ee1bb 263 SUPERFAMILY SSF64438 5 262 1.53E-74 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CWR44_RS08340 4acf6d2dba01ea446adc9fb2782ee1bb 263 Gene3D G3DSA:3.60.140.10 2 263 1.1E-62 T 28-03-2018 CWR44_RS08340 4acf6d2dba01ea446adc9fb2782ee1bb 263 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 34 261 6.2E-47 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CWR44_RS08340 4acf6d2dba01ea446adc9fb2782ee1bb 263 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 27 260 1.9E-55 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 Pfam PF00245 Alkaline phosphatase 57 478 5.0E-111 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 ProSitePatterns PS00123 Alkaline phosphatase active site. 111 119 - T 28-03-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 SMART SM00098 57 483 5.8E-133 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 SUPERFAMILY SSF53649 41 387 6.94E-122 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 SUPERFAMILY SSF53649 424 482 6.94E-122 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 PRINTS PR00113 Alkaline phosphatase signature 111 126 2.8E-40 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 PRINTS PR00113 Alkaline phosphatase signature 148 168 2.8E-40 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 PRINTS PR00113 Alkaline phosphatase signature 264 293 2.8E-40 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 PRINTS PR00113 Alkaline phosphatase signature 198 208 2.8E-40 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 PRINTS PR00113 Alkaline phosphatase signature 56 76 2.8E-40 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CWR44_RS02675 7aef4ce7ac4ebd3b974eb063aac71129 489 Gene3D G3DSA:3.40.720.10 25 488 7.7E-118 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWR44_RS02035 f60097c5ddec93a95ef96bb488b14214 497 Gene3D G3DSA:3.40.605.10 2 271 6.0E-92 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS02035 f60097c5ddec93a95ef96bb488b14214 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS02035 f60097c5ddec93a95ef96bb488b14214 497 SUPERFAMILY SSF53720 9 490 3.93E-160 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR44_RS02035 f60097c5ddec93a95ef96bb488b14214 497 Pfam PF00171 Aldehyde dehydrogenase family 24 485 1.5E-167 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS02035 f60097c5ddec93a95ef96bb488b14214 497 Gene3D G3DSA:3.40.309.10 272 471 3.3E-69 T 28-03-2018 CWR44_RS02035 f60097c5ddec93a95ef96bb488b14214 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS08375 6acc4c3ec3e28eeb8c339f03aead4405 501 Gene3D G3DSA:3.40.50.720 1 318 1.6E-25 T 28-03-2018 CWR44_RS08375 6acc4c3ec3e28eeb8c339f03aead4405 501 Pfam PF13460 NAD(P)H-binding 8 114 3.2E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS08375 6acc4c3ec3e28eeb8c339f03aead4405 501 SUPERFAMILY SSF51735 1 263 8.86E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10115 e265835f70514eb69a4edaa0bd28fdfd 175 SUPERFAMILY SSF55068 2 165 1.11E-68 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS10115 e265835f70514eb69a4edaa0bd28fdfd 175 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 4 153 4.5E-58 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS10115 e265835f70514eb69a4edaa0bd28fdfd 175 Pfam PF01625 Peptide methionine sulfoxide reductase 4 154 4.4E-58 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS10115 e265835f70514eb69a4edaa0bd28fdfd 175 Gene3D G3DSA:3.30.1060.10 1 170 4.7E-62 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS10115 e265835f70514eb69a4edaa0bd28fdfd 175 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 160 35.985 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS05770 34b23cf68ffcaccd8bfca1f83e24f940 188 Gene3D G3DSA:3.40.50.360 1 184 6.7E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS05770 34b23cf68ffcaccd8bfca1f83e24f940 188 Pfam PF03358 NADPH-dependent FMN reductase 1 141 9.2E-26 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWR44_RS05770 34b23cf68ffcaccd8bfca1f83e24f940 188 SUPERFAMILY SSF52218 1 174 3.26E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS06195 6daf2d797b438dd758a036e4e55d3496 680 Pfam PF00999 Sodium/hydrogen exchanger family 8 425 3.2E-52 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CWR44_RS00240 a7957fbffd8c5dbc8ca2ba399e277ac0 475 Gene3D G3DSA:3.40.605.10 1 259 8.8E-85 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS00240 a7957fbffd8c5dbc8ca2ba399e277ac0 475 SUPERFAMILY SSF53720 4 470 3.4E-150 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR44_RS00240 a7957fbffd8c5dbc8ca2ba399e277ac0 475 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS00240 a7957fbffd8c5dbc8ca2ba399e277ac0 475 Gene3D G3DSA:3.40.309.10 260 456 1.4E-70 T 28-03-2018 CWR44_RS00240 a7957fbffd8c5dbc8ca2ba399e277ac0 475 Pfam PF00171 Aldehyde dehydrogenase family 13 470 4.9E-162 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS00240 a7957fbffd8c5dbc8ca2ba399e277ac0 475 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 SUPERFAMILY SSF52540 295 519 1.96E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 SUPERFAMILY SSF48334 22 290 4.05E-18 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 Pfam PF01713 Smr domain 708 783 9.6E-20 T 28-03-2018 IPR002625 Smr domain CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 783 1.4E-239 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 SUPERFAMILY SSF160443 706 782 1.96E-10 T 28-03-2018 IPR002625 Smr domain CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 412 428 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 Pfam PF00488 MutS domain V 333 513 1.5E-34 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 782 21.308 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 PIRSF PIRSF005814 1 783 4.1E-280 T 28-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 Gene3D G3DSA:3.40.50.300 294 556 3.0E-33 T 28-03-2018 CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 SMART SM00463 705 783 1.3E-24 T 28-03-2018 IPR002625 Smr domain CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 SMART SM00533 9 317 2.1E-6 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR44_RS08200 ffeb26b52be793c7306dba1ef024de86 783 SMART SM00534 330 515 2.3E-84 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR44_RS12515 f9463775acc8ff1e8cd8056abbda38fa 186 SUPERFAMILY SSF52833 33 151 1.33E-8 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS12515 f9463775acc8ff1e8cd8056abbda38fa 186 Gene3D G3DSA:3.40.30.10 1 183 5.1E-12 T 28-03-2018 CWR44_RS12515 f9463775acc8ff1e8cd8056abbda38fa 186 Pfam PF14595 Thioredoxin 14 138 6.6E-39 T 28-03-2018 CWR44_RS00750 0964968342ea32a0543eb1b5f0f3fa7a 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 1.0E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00750 0964968342ea32a0543eb1b5f0f3fa7a 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 1.0E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00750 0964968342ea32a0543eb1b5f0f3fa7a 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 1.0E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00750 0964968342ea32a0543eb1b5f0f3fa7a 87 Pfam PF00366 Ribosomal protein S17 12 79 5.5E-31 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00750 0964968342ea32a0543eb1b5f0f3fa7a 87 Gene3D G3DSA:2.40.50.140 7 84 7.3E-30 T 28-03-2018 CWR44_RS00750 0964968342ea32a0543eb1b5f0f3fa7a 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 7.6E-34 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00750 0964968342ea32a0543eb1b5f0f3fa7a 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00750 0964968342ea32a0543eb1b5f0f3fa7a 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 9.0E-35 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00750 0964968342ea32a0543eb1b5f0f3fa7a 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 23.745 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00750 0964968342ea32a0543eb1b5f0f3fa7a 87 SUPERFAMILY SSF50249 7 83 2.14E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 37 196 1.0E-53 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 225 360 9.9E-44 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 SUPERFAMILY SSF52518 396 588 1.97E-69 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 Gene3D G3DSA:3.40.50.1220 227 375 5.6E-49 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 SUPERFAMILY SSF52467 219 385 2.39E-57 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 455 474 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 Gene3D G3DSA:3.40.50.970 29 226 6.0E-59 T 28-03-2018 CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 418 566 1.3E-49 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 SUPERFAMILY SSF52518 34 212 4.3E-59 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 37 588 1.8E-225 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CWR44_RS12725 ebf4c843e150fddda7fdddb0b9a7d3fc 591 Gene3D G3DSA:3.40.50.970 376 586 9.3E-54 T 28-03-2018 CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 9.0E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.0E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 9.0E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 9.0E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 9.0E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 9.0E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 Pfam PF00106 short chain dehydrogenase 8 193 6.7E-53 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 210 0.0084 T 28-03-2018 CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 SUPERFAMILY SSF51735 1 227 2.38E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS01860 82791b1e4699d7fdaada82e5fc1c552b 231 Gene3D G3DSA:3.40.50.720 1 229 4.8E-59 T 28-03-2018 CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 SMART SM00491 733 861 1.2E-11 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 Gene3D G3DSA:3.40.50.300 248 685 1.1E-16 T 28-03-2018 CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 168 3.2E-28 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 Gene3D G3DSA:1.20.5.140 155 174 5.2E-4 T 28-03-2018 CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 Gene3D G3DSA:3.30.420.10 2 154 1.6E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 6 894 0.0 T 28-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 Pfam PF13307 Helicase C-terminal domain 716 874 2.9E-29 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 SMART SM00479 5 171 3.5E-35 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 SUPERFAMILY SSF53098 5 226 7.15E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 SUPERFAMILY SSF52540 401 470 7.24E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 SUPERFAMILY SSF52540 690 856 7.24E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 SUPERFAMILY SSF52540 643 657 7.24E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 SUPERFAMILY SSF52540 262 319 7.24E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 Pfam PF04851 Type III restriction enzyme, res subunit 250 476 5.6E-6 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 Pfam PF00929 Exonuclease 8 161 9.4E-28 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR44_RS10245 b4fc3b39fcec3bddb0e193901bcbc662 900 Gene3D G3DSA:3.40.50.300 696 900 2.8E-11 T 28-03-2018 CWR44_RS01175 023d92537a236c4154f7373c7dc9b701 363 Pfam PF02517 CAAX protease self-immunity 121 214 1.9E-4 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR44_RS08900 df6232db3ba33ee30e7b7def61ddbd66 177 SUPERFAMILY SSF110391 5 177 4.71E-57 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CWR44_RS08900 df6232db3ba33ee30e7b7def61ddbd66 177 Gene3D G3DSA:3.20.20.400 1 177 5.3E-63 T 28-03-2018 CWR44_RS08900 df6232db3ba33ee30e7b7def61ddbd66 177 PIRSF PIRSF016897 1 177 6.0E-62 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CWR44_RS08900 df6232db3ba33ee30e7b7def61ddbd66 177 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 5 177 1.2E-58 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 Gene3D G3DSA:3.30.360.10 123 212 2.0E-33 T 28-03-2018 CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 Gene3D G3DSA:3.40.50.720 1 122 3.0E-17 T 28-03-2018 CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 107 6.7E-16 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 43 240 3.9E-52 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 240 25.405 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 PIRSF PIRSF000161 1 241 1.2E-74 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 131 148 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 SUPERFAMILY SSF55347 110 214 2.07E-28 T 28-03-2018 CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 SUPERFAMILY SSF51735 1 106 6.88E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 SUPERFAMILY SSF51735 213 240 6.88E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS09975 73a194c72e649df69a0c8e6887dd0e71 241 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 110 240 2.2E-38 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS11750 31cdf992f724fc60aec53af6db454942 283 Gene3D G3DSA:1.10.530.10 123 265 7.4E-26 T 28-03-2018 CWR44_RS11750 31cdf992f724fc60aec53af6db454942 283 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 132 260 1.6E-13 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR44_RS11750 31cdf992f724fc60aec53af6db454942 283 SMART SM00047 113 271 1.8E-34 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR44_RS08765 0436603821de64c314dc68fe0aad91ed 305 SUPERFAMILY SSF55120 1 238 5.47E-77 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS08765 0436603821de64c314dc68fe0aad91ed 305 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 304 18.734 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS08765 0436603821de64c314dc68fe0aad91ed 305 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 3 217 1.7E-78 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS08765 0436603821de64c314dc68fe0aad91ed 305 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 179 4.5E-56 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CWR44_RS08765 0436603821de64c314dc68fe0aad91ed 305 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 238 2.3E-13 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CWR44_RS08765 0436603821de64c314dc68fe0aad91ed 305 Gene3D G3DSA:3.30.2350.10 1 229 9.0E-79 T 28-03-2018 CWR44_RS00885 25acf4ad1024415ab83e9d38f8246b8f 201 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 195 19.993 T 28-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CWR44_RS00885 25acf4ad1024415ab83e9d38f8246b8f 201 Pfam PF12804 MobA-like NTP transferase domain 3 164 1.7E-25 T 28-03-2018 IPR025877 MobA-like NTP transferase CWR44_RS00885 25acf4ad1024415ab83e9d38f8246b8f 201 Gene3D G3DSA:3.90.550.10 1 201 2.9E-27 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS00885 25acf4ad1024415ab83e9d38f8246b8f 201 SUPERFAMILY SSF53448 1 193 4.51E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS00655 d45dab87c4e6beb0b444b1fbdbf453b5 270 Pfam PF00005 ABC transporter 26 172 1.6E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS00655 d45dab87c4e6beb0b444b1fbdbf453b5 270 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS00655 d45dab87c4e6beb0b444b1fbdbf453b5 270 SMART SM00382 35 220 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS00655 d45dab87c4e6beb0b444b1fbdbf453b5 270 Gene3D G3DSA:3.40.50.300 4 243 2.2E-66 T 28-03-2018 CWR44_RS00655 d45dab87c4e6beb0b444b1fbdbf453b5 270 SUPERFAMILY SSF52540 7 236 3.63E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00655 d45dab87c4e6beb0b444b1fbdbf453b5 270 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 9 256 1.4E-102 T 28-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 CWR44_RS07410 71b0d62cdb3320c03c8ad635defb2734 301 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 95 298 2.3E-60 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR44_RS07410 71b0d62cdb3320c03c8ad635defb2734 301 SUPERFAMILY SSF56529 81 298 1.05E-68 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR44_RS07410 71b0d62cdb3320c03c8ad635defb2734 301 Gene3D G3DSA:3.90.850.10 60 301 3.5E-71 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR44_RS05530 03d041b4212b4d2ed13fd4c7a171aed7 187 PIRSF PIRSF015034 1 187 5.7E-50 T 28-03-2018 IPR025542 YacH protein CWR44_RS05530 03d041b4212b4d2ed13fd4c7a171aed7 187 Gene3D G3DSA:4.10.860.10 108 183 6.7E-9 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWR44_RS05530 03d041b4212b4d2ed13fd4c7a171aed7 187 Pfam PF02151 UvrB/uvrC motif 145 179 2.9E-6 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWR44_RS11130 98865b4589846d010806bde947ed06c6 106 Pfam PF04327 Cysteine protease Prp 1 101 4.4E-23 T 28-03-2018 IPR007422 Cysteine protease Prp CWR44_RS11130 98865b4589846d010806bde947ed06c6 106 Gene3D G3DSA:3.30.70.1490 1 106 1.1E-27 T 28-03-2018 IPR007422 Cysteine protease Prp CWR44_RS11130 98865b4589846d010806bde947ed06c6 106 SUPERFAMILY SSF118010 1 106 1.03E-31 T 28-03-2018 IPR007422 Cysteine protease Prp CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 Pfam PF07478 D-ala D-ala ligase C-terminus 136 339 4.2E-76 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 SUPERFAMILY SSF52440 3 128 6.62E-32 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 SUPERFAMILY SSF56059 129 344 3.72E-56 T 28-03-2018 CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 341 5.6E-107 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 Pfam PF01820 D-ala D-ala ligase N-terminus 5 118 2.5E-28 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 Gene3D G3DSA:3.30.1490.20 144 204 5.1E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 96 107 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 Gene3D G3DSA:3.40.50.20 1 139 1.8E-39 T 28-03-2018 CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 PIRSF PIRSF039102 1 350 6.1E-111 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 342 40.445 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 284 312 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS12870 7ff99967fc96251b076c5eb87202fcfb 356 Gene3D G3DSA:3.30.470.20 205 351 9.1E-39 T 28-03-2018 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 Pfam PF07478 D-ala D-ala ligase C-terminus 136 339 4.2E-76 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 SUPERFAMILY SSF52440 3 128 6.62E-32 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 SUPERFAMILY SSF56059 129 344 3.72E-56 T 28-03-2018 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 341 5.6E-107 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 Pfam PF01820 D-ala D-ala ligase N-terminus 5 118 2.5E-28 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 Gene3D G3DSA:3.30.1490.20 144 204 5.1E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 96 107 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 Gene3D G3DSA:3.40.50.20 1 139 1.8E-39 T 28-03-2018 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 PIRSF PIRSF039102 1 350 6.1E-111 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 342 40.445 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 284 312 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00040 7ff99967fc96251b076c5eb87202fcfb 356 Gene3D G3DSA:3.30.470.20 205 351 9.1E-39 T 28-03-2018 CWR44_RS11790 db353d50eb22ad3505118d19bfaa1ce0 117 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 114 3.1E-22 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CWR44_RS11790 db353d50eb22ad3505118d19bfaa1ce0 117 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 116 16.186 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 Gene3D G3DSA:3.30.572.10 1 318 1.4E-127 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 PRINTS PR00108 Thymidylate synthase family signature 214 240 5.3E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 PRINTS PR00108 Thymidylate synthase family signature 252 269 5.3E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 PRINTS PR00108 Thymidylate synthase family signature 170 189 5.3E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 PRINTS PR00108 Thymidylate synthase family signature 47 68 5.3E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 PRINTS PR00108 Thymidylate synthase family signature 196 211 5.3E-50 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 SUPERFAMILY SSF55831 6 318 3.01E-129 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 ProSitePatterns PS00091 Thymidylate synthase active site. 181 209 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 Pfam PF00303 Thymidylate synthase 8 318 8.2E-117 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 Hamap MF_00008 Thymidylate synthase [thyA]. 6 318 38.486 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS10130 3738d59dcf08d83ec729058b62add464 318 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 8 318 1.2E-159 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 4.1E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 Pfam PF03144 Elongation factor Tu domain 2 308 373 1.3E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 4 518 4.1E-197 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 SUPERFAMILY SSF52540 7 270 3.56E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 Pfam PF16658 Class II release factor RF3, C-terminal domain 382 507 1.8E-45 T 28-03-2018 IPR032090 Peptide chain release factor 3, C-terminal CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 SUPERFAMILY SSF50447 255 379 4.95E-26 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 SUPERFAMILY SSF54980 388 459 2.05E-17 T 28-03-2018 IPR035647 EF-G domain III/V-like CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 Pfam PF00009 Elongation factor Tu GTP binding domain 12 270 4.8E-56 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 520 49.666 T 28-03-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 PRINTS PR00315 GTP-binding elongation factor signature 98 109 1.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 PRINTS PR00315 GTP-binding elongation factor signature 134 143 1.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 PRINTS PR00315 GTP-binding elongation factor signature 62 70 1.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 PRINTS PR00315 GTP-binding elongation factor signature 82 92 1.9E-11 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 Gene3D G3DSA:2.40.30.10 266 385 9.6E-23 T 28-03-2018 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 Gene3D G3DSA:3.30.70.870 388 460 3.2E-13 T 28-03-2018 CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWR44_RS07610 bb338b4fd54b41a3d9a68a16e32550c9 520 Gene3D G3DSA:3.40.50.300 4 265 6.7E-42 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 860 887 - T 28-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Pfam PF01568 Molydopterin dinucleotide binding domain 821 932 1.1E-17 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 190 201 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 5 77 9.7E-11 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 SMART SM00929 84 125 9.7E-12 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 SUPERFAMILY SSF54862 77 210 9.63E-28 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Gene3D G3DSA:2.40.40.20 810 965 3.6E-21 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Pfam PF00384 Molybdopterin oxidoreductase 314 737 2.1E-76 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Gene3D G3DSA:3.40.228.10 418 509 1.2E-17 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 257 311 3.8E-18 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 262 935 1.4E-240 T 28-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 262 279 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 SUPERFAMILY SSF50692 786 937 2.26E-28 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Gene3D G3DSA:3.10.20.30 2 99 9.0E-7 T 28-03-2018 IPR012675 Beta-grasp domain CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 PIRSF PIRSF036643 1 970 0.0 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 SMART SM00926 257 311 4.3E-17 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Gene3D G3DSA:3.30.70.20 151 217 1.6E-11 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 84 123 1.0E-8 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Gene3D G3DSA:2.20.25.90 257 312 3.3E-18 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Gene3D G3DSA:3.30.70.20 100 150 0.0022 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 SUPERFAMILY SSF53706 251 775 1.31E-188 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 SUPERFAMILY SSF54292 6 74 2.14E-12 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Gene3D G3DSA:3.40.50.740 314 417 6.4E-25 T 28-03-2018 CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Pfam PF12838 4Fe-4S dicluster domain 146 204 2.4E-6 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR44_RS01055 1cac48ca265b9c8b86caf4ff5ce607cc 984 Gene3D G3DSA:3.40.50.740 510 789 3.1E-76 T 28-03-2018 CWR44_RS00575 ee967506c3f17f24dd6917a600f792f3 333 Gene3D G3DSA:3.20.20.30 1 331 1.7E-60 T 28-03-2018 CWR44_RS00575 ee967506c3f17f24dd6917a600f792f3 333 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 330 1.2E-110 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CWR44_RS00575 ee967506c3f17f24dd6917a600f792f3 333 Pfam PF00296 Luciferase-like monooxygenase 19 271 2.3E-25 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CWR44_RS00575 ee967506c3f17f24dd6917a600f792f3 333 SUPERFAMILY SSF51679 1 330 4.84E-58 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CWR44_RS01090 fa843f9d734390e66d1b8669ab721828 477 SUPERFAMILY SSF55604 7 81 3.01E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS01090 fa843f9d734390e66d1b8669ab721828 477 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS01090 fa843f9d734390e66d1b8669ab721828 477 Pfam PF00367 phosphotransferase system, EIIB 10 42 9.1E-12 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS01090 fa843f9d734390e66d1b8669ab721828 477 Pfam PF02378 Phosphotransferase system, EIIC 127 408 3.5E-33 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS01090 fa843f9d734390e66d1b8669ab721828 477 Gene3D G3DSA:3.30.1360.60 5 81 1.4E-22 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS08415 f8a3f9fef077bfb6b269bb90e1de8a7e 424 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08415 f8a3f9fef077bfb6b269bb90e1de8a7e 424 ProSitePatterns PS00482 Dihydroorotase signature 1. 56 64 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08415 f8a3f9fef077bfb6b269bb90e1de8a7e 424 SUPERFAMILY SSF51556 53 367 1.93E-112 T 28-03-2018 IPR032466 Metal-dependent hydrolase CWR44_RS08415 f8a3f9fef077bfb6b269bb90e1de8a7e 424 Gene3D G3DSA:3.20.20.140 67 405 1.2E-108 T 28-03-2018 CWR44_RS08415 f8a3f9fef077bfb6b269bb90e1de8a7e 424 Hamap MF_00220_B Dihydroorotase [pyrC]. 1 423 46.982 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08415 f8a3f9fef077bfb6b269bb90e1de8a7e 424 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 422 1.5E-144 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08415 f8a3f9fef077bfb6b269bb90e1de8a7e 424 Gene3D G3DSA:2.30.40.10 2 66 3.2E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR44_RS08415 f8a3f9fef077bfb6b269bb90e1de8a7e 424 Pfam PF01979 Amidohydrolase family 49 418 6.6E-47 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR44_RS08415 f8a3f9fef077bfb6b269bb90e1de8a7e 424 SUPERFAMILY SSF51338 365 423 6.65E-28 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR44_RS08415 f8a3f9fef077bfb6b269bb90e1de8a7e 424 SUPERFAMILY SSF51338 3 52 6.65E-28 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR44_RS10005 f89b72da0dac89fc7bc4f5579a32fa48 66 Gene3D G3DSA:2.40.50.140 1 66 9.7E-28 T 28-03-2018 CWR44_RS10005 f89b72da0dac89fc7bc4f5579a32fa48 66 SMART SM00357 3 66 1.3E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CWR44_RS10005 f89b72da0dac89fc7bc4f5579a32fa48 66 PRINTS PR00050 Cold shock protein signature 4 19 4.2E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR44_RS10005 f89b72da0dac89fc7bc4f5579a32fa48 66 PRINTS PR00050 Cold shock protein signature 39 57 4.2E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR44_RS10005 f89b72da0dac89fc7bc4f5579a32fa48 66 PRINTS PR00050 Cold shock protein signature 24 33 4.2E-20 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR44_RS10005 f89b72da0dac89fc7bc4f5579a32fa48 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CWR44_RS10005 f89b72da0dac89fc7bc4f5579a32fa48 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 6.1E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR44_RS10005 f89b72da0dac89fc7bc4f5579a32fa48 66 SUPERFAMILY SSF50249 1 65 4.43E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS10005 f89b72da0dac89fc7bc4f5579a32fa48 66 PIRSF PIRSF002599 1 66 1.0E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 Gene3D G3DSA:3.90.79.10 228 348 1.2E-7 T 28-03-2018 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 Pfam PF00633 Helix-hairpin-helix motif 99 128 1.7E-5 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 191 207 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 Gene3D G3DSA:1.10.1670.10 118 224 4.7E-31 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 SUPERFAMILY SSF55811 219 346 2.27E-18 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 SUPERFAMILY SSF48150 7 221 2.67E-69 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 165 3.1E-17 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 Gene3D G3DSA:1.10.340.30 21 117 5.7E-29 T 28-03-2018 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 SMART SM00478 39 189 8.1E-43 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 Pfam PF14815 NUDIX domain 234 344 3.2E-19 T 28-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR44_RS12215 5f8184d8921440153f39813a171b65b7 348 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 7 276 7.9E-98 T 28-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CWR44_RS10600 66f13ee68950fdfe3d17fb38a3be76be 450 PIRSF PIRSF006815 3 447 6.7E-182 T 28-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CWR44_RS10600 66f13ee68950fdfe3d17fb38a3be76be 450 Gene3D G3DSA:3.90.1150.10 338 447 2.1E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS10600 66f13ee68950fdfe3d17fb38a3be76be 450 SUPERFAMILY SSF53383 3 441 3.02E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS10600 66f13ee68950fdfe3d17fb38a3be76be 450 Gene3D G3DSA:3.40.640.10 84 337 3.6E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS10600 66f13ee68950fdfe3d17fb38a3be76be 450 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 48.98 T 28-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CWR44_RS10600 66f13ee68950fdfe3d17fb38a3be76be 450 Pfam PF02347 Glycine cleavage system P-protein 3 440 7.5E-151 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CWR44_RS10660 a8a33ab2bdaf320ff3e7167c5e56016b 328 Gene3D G3DSA:3.30.420.40 1 125 1.9E-26 T 28-03-2018 CWR44_RS10660 a8a33ab2bdaf320ff3e7167c5e56016b 328 SUPERFAMILY SSF53067 4 318 1.11E-64 T 28-03-2018 CWR44_RS10660 a8a33ab2bdaf320ff3e7167c5e56016b 328 ProSitePatterns PS01125 ROK family signature. 140 167 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWR44_RS10660 a8a33ab2bdaf320ff3e7167c5e56016b 328 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 326 1.5E-147 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CWR44_RS10660 a8a33ab2bdaf320ff3e7167c5e56016b 328 Gene3D G3DSA:3.30.420.40 126 324 2.3E-53 T 28-03-2018 CWR44_RS10660 a8a33ab2bdaf320ff3e7167c5e56016b 328 Pfam PF00480 ROK family 7 319 4.8E-64 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWR44_RS13115 f5b77bdd4e4326a1c31aef1e0b019603 186 Pfam PF08360 QacR-like protein, C-terminal region 55 186 5.1E-61 T 28-03-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 CWR44_RS13115 f5b77bdd4e4326a1c31aef1e0b019603 186 SUPERFAMILY SSF46689 2 63 1.64E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS13115 f5b77bdd4e4326a1c31aef1e0b019603 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS13115 f5b77bdd4e4326a1c31aef1e0b019603 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS13115 f5b77bdd4e4326a1c31aef1e0b019603 186 Gene3D G3DSA:1.10.10.60 38 73 2.2E-8 T 28-03-2018 CWR44_RS13115 f5b77bdd4e4326a1c31aef1e0b019603 186 SUPERFAMILY SSF48498 71 184 9.56E-39 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CWR44_RS13115 f5b77bdd4e4326a1c31aef1e0b019603 186 Gene3D G3DSA:1.10.10.60 1 37 1.9E-11 T 28-03-2018 CWR44_RS13115 f5b77bdd4e4326a1c31aef1e0b019603 186 ProSitePatterns PS01081 TetR-type HTH domain signature. 17 47 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CWR44_RS13115 f5b77bdd4e4326a1c31aef1e0b019603 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 51 2.2E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS06015 1504a218bdb8bbc83bade2cdbb1f6da7 203 Pfam PF00239 Resolvase, N terminal domain 2 145 1.2E-33 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS06015 1504a218bdb8bbc83bade2cdbb1f6da7 203 Pfam PF02796 Helix-turn-helix domain of resolvase 147 199 2.6E-20 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS06015 1504a218bdb8bbc83bade2cdbb1f6da7 203 Gene3D G3DSA:1.10.10.60 146 200 4.0E-15 T 28-03-2018 CWR44_RS06015 1504a218bdb8bbc83bade2cdbb1f6da7 203 SMART SM00857 2 145 4.1E-42 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS06015 1504a218bdb8bbc83bade2cdbb1f6da7 203 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CWR44_RS06015 1504a218bdb8bbc83bade2cdbb1f6da7 203 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CWR44_RS06015 1504a218bdb8bbc83bade2cdbb1f6da7 203 SUPERFAMILY SSF53041 1 145 9.16E-36 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS06015 1504a218bdb8bbc83bade2cdbb1f6da7 203 Gene3D G3DSA:1.20.5.40 115 143 4.2E-9 T 28-03-2018 CWR44_RS06015 1504a218bdb8bbc83bade2cdbb1f6da7 203 Gene3D G3DSA:3.40.50.1390 1 114 6.6E-31 T 28-03-2018 CWR44_RS07915 41e2e6a855d550c571aeaff616400830 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CWR44_RS07915 41e2e6a855d550c571aeaff616400830 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.3E-30 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR44_RS07915 41e2e6a855d550c571aeaff616400830 88 SUPERFAMILY SSF55594 1 83 1.14E-28 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR44_RS07915 41e2e6a855d550c571aeaff616400830 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 2.0E-34 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR44_RS07915 41e2e6a855d550c571aeaff616400830 88 Gene3D G3DSA:3.30.1340.10 1 88 2.2E-33 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR44_RS07915 41e2e6a855d550c571aeaff616400830 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.8E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR44_RS07915 41e2e6a855d550c571aeaff616400830 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.8E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR44_RS07915 41e2e6a855d550c571aeaff616400830 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.8E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CWR44_RS07915 41e2e6a855d550c571aeaff616400830 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 28-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CWR44_RS09440 21059a83dc16f4c64699cfcd75675c10 66 SUPERFAMILY SSF47413 2 61 1.58E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS09440 21059a83dc16f4c64699cfcd75675c10 66 Pfam PF01381 Helix-turn-helix 2 52 3.7E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS09440 21059a83dc16f4c64699cfcd75675c10 66 Gene3D G3DSA:1.10.260.40 2 59 8.0E-13 T 28-03-2018 CWR44_RS11815 8a39d72ca549056e010103441a653bd4 256 Pfam PF00326 Prolyl oligopeptidase family 87 253 2.0E-9 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CWR44_RS11815 8a39d72ca549056e010103441a653bd4 256 Gene3D G3DSA:3.40.50.1820 12 255 3.9E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS11815 8a39d72ca549056e010103441a653bd4 256 SUPERFAMILY SSF53474 18 253 4.02E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 59 72 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 Gene3D G3DSA:1.10.1740.10 19 102 1.6E-19 T 28-03-2018 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 253 3.2E-37 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 Gene3D G3DSA:1.10.10.10 106 158 8.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 Pfam PF04542 Sigma-70 region 2 35 104 1.4E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 SUPERFAMILY SSF88659 108 183 1.66E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 224 250 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 SUPERFAMILY SSF88946 10 104 1.44E-25 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 3 255 7.1E-143 T 28-03-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 Gene3D G3DSA:1.10.10.10 182 256 1.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 PRINTS PR00046 Major sigma-70 factor signature 59 72 1.1E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 PRINTS PR00046 Major sigma-70 factor signature 224 239 1.1E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 PRINTS PR00046 Major sigma-70 factor signature 207 219 1.1E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 PRINTS PR00046 Major sigma-70 factor signature 239 250 1.1E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 29 254 1.6E-91 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 Pfam PF04545 Sigma-70, region 4 205 251 2.9E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 Pfam PF04539 Sigma-70 region 3 117 188 1.2E-17 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS12805 b3c76ea66e1ce874634a81b2f376a4d5 256 SUPERFAMILY SSF88659 179 254 5.05E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS09110 ea476c173059762e93986722c580c826 104 Gene3D G3DSA:3.40.1800.10 20 101 8.2E-11 T 28-03-2018 CWR44_RS09110 ea476c173059762e93986722c580c826 104 Pfam PF01844 HNH endonuclease 41 88 9.4E-11 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CWR44_RS09110 ea476c173059762e93986722c580c826 104 SMART SM00507 28 84 0.0013 T 28-03-2018 IPR003615 HNH nuclease CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 Gene3D G3DSA:3.20.190.10 2 145 4.1E-27 T 28-03-2018 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 134 3.2E-26 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 289 1.2E-71 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 SUPERFAMILY SSF81624 2 139 1.44E-26 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 151 241 9.1E-19 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 SUPERFAMILY SSF46946 150 241 1.31E-24 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 SUPERFAMILY SSF57716 240 290 3.14E-12 T 28-03-2018 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 SMART SM01232 150 244 3.6E-32 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 Gene3D G3DSA:1.10.8.50 152 290 1.4E-38 T 28-03-2018 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 Pfam PF06827 Zinc finger found in FPG and IleRS 263 290 1.3E-7 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 SMART SM00898 2 136 2.7E-32 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CWR44_RS11310 9b2d1abe416c348d29e437fe61acb476 290 ProSitePatterns PS01242 Zinc finger FPG-type signature. 265 289 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 Gene3D G3DSA:3.90.110.10 144 316 2.2E-43 T 28-03-2018 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 146 305 4.2E-26 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 PIRSF PIRSF000102 1 315 7.5E-95 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 173 179 - T 28-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 SUPERFAMILY SSF51735 3 145 1.28E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 8 303 4.7E-109 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 Gene3D G3DSA:3.40.50.720 4 143 1.8E-30 T 28-03-2018 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 3 311 39.352 T 28-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 143 1.4E-35 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 SUPERFAMILY SSF56327 144 309 6.63E-50 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 PRINTS PR00086 L-lactate dehydrogenase signature 30 54 1.0E-41 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 PRINTS PR00086 L-lactate dehydrogenase signature 141 159 1.0E-41 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 PRINTS PR00086 L-lactate dehydrogenase signature 117 137 1.0E-41 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 PRINTS PR00086 L-lactate dehydrogenase signature 171 184 1.0E-41 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR44_RS02135 9c24c9f3f35d2f37164208b390fdcaf0 318 PRINTS PR00086 L-lactate dehydrogenase signature 5 29 1.0E-41 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CWR44_RS06505 e846b47718db4f4f53943dc41ab538bd 139 Pfam PF03479 Domain of unknown function (DUF296) 9 118 8.5E-20 T 28-03-2018 IPR005175 PPC domain CWR44_RS06505 e846b47718db4f4f53943dc41ab538bd 139 PIRSF PIRSF016702 1 139 1.3E-49 T 28-03-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif CWR44_RS06505 e846b47718db4f4f53943dc41ab538bd 139 Gene3D G3DSA:3.30.1330.80 1 139 1.4E-31 T 28-03-2018 CWR44_RS06505 e846b47718db4f4f53943dc41ab538bd 139 SUPERFAMILY SSF117856 1 137 6.28E-38 T 28-03-2018 CWR44_RS06790 7a1cd2df88374881d3e41f0d218ae7e6 429 SUPERFAMILY SSF52540 115 399 7.99E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06790 7a1cd2df88374881d3e41f0d218ae7e6 429 Gene3D G3DSA:3.40.50.300 93 264 3.6E-20 T 28-03-2018 CWR44_RS06790 7a1cd2df88374881d3e41f0d218ae7e6 429 Pfam PF00271 Helicase conserved C-terminal domain 287 388 6.6E-8 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS06790 7a1cd2df88374881d3e41f0d218ae7e6 429 Pfam PF04851 Type III restriction enzyme, res subunit 94 242 3.4E-9 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWR44_RS06790 7a1cd2df88374881d3e41f0d218ae7e6 429 SMART SM00487 92 274 2.2E-12 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS06790 7a1cd2df88374881d3e41f0d218ae7e6 429 Gene3D G3DSA:3.40.50.300 270 420 4.4E-15 T 28-03-2018 CWR44_RS06790 7a1cd2df88374881d3e41f0d218ae7e6 429 SMART SM00490 310 389 1.6E-4 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS01805 1687c87c4de63c793c58f643aa0f415f 266 Pfam PF02517 CAAX protease self-immunity 165 255 9.5E-11 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR44_RS08080 665119dc3fa704d9a669cbcb63bb4094 92 Hamap MF_01560 UPF0358 protein . 1 91 25.331 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CWR44_RS08080 665119dc3fa704d9a669cbcb63bb4094 92 Pfam PF07408 Protein of unknown function (DUF1507) 8 89 3.4E-38 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CWR44_RS08080 665119dc3fa704d9a669cbcb63bb4094 92 SUPERFAMILY SSF140404 4 82 1.27E-35 T 28-03-2018 IPR009983 Uncharacterised protein family UPF0358 CWR44_RS08080 665119dc3fa704d9a669cbcb63bb4094 92 Gene3D G3DSA:1.10.287.750 6 88 4.5E-39 T 28-03-2018 CWR44_RS02090 49816172f4eaef839f47621c7c37672d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 76 101 5.1E-39 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS02090 49816172f4eaef839f47621c7c37672d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 241 257 5.1E-39 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS02090 49816172f4eaef839f47621c7c37672d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 270 289 5.1E-39 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS02090 49816172f4eaef839f47621c7c37672d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 359 377 5.1E-39 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS02090 49816172f4eaef839f47621c7c37672d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 413 428 5.1E-39 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS02090 49816172f4eaef839f47621c7c37672d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 133 151 5.1E-39 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS02090 49816172f4eaef839f47621c7c37672d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 151 170 5.1E-39 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS02090 49816172f4eaef839f47621c7c37672d 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 436 453 5.1E-39 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS02090 49816172f4eaef839f47621c7c37672d 531 Pfam PF01019 Gamma-glutamyltranspeptidase 69 518 3.6E-80 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS02090 49816172f4eaef839f47621c7c37672d 531 SUPERFAMILY SSF56235 50 527 2.51E-100 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS07135 f2d53dcb74474c2ec1f14b08c918f25c 283 Pfam PF04018 Domain of unknown function (DUF368) 15 250 2.7E-52 T 28-03-2018 IPR007163 Protein of unknown function DUF368 CWR44_RS04160 afd28bbdd0cf2d27c860a95a388357f2 108 SUPERFAMILY SSF46785 14 107 1.82E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04160 afd28bbdd0cf2d27c860a95a388357f2 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.8E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS04160 afd28bbdd0cf2d27c860a95a388357f2 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 1.8E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS04160 afd28bbdd0cf2d27c860a95a388357f2 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 1.8E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS04160 afd28bbdd0cf2d27c860a95a388357f2 108 Pfam PF01022 Bacterial regulatory protein, arsR family 32 77 2.1E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS04160 afd28bbdd0cf2d27c860a95a388357f2 108 Gene3D G3DSA:1.10.10.10 1 108 1.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04160 afd28bbdd0cf2d27c860a95a388357f2 108 SMART SM00418 25 103 8.0E-29 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 Gene3D G3DSA:1.20.1250.20 3 200 2.0E-28 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 203 221 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 258 283 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 329 349 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 349 369 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 78 100 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 294 318 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 391 410 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 165 189 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 PRINTS PR01036 Tetracycline resistance protein TetB signature 224 242 8.1E-162 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 Gene3D G3DSA:1.20.1250.20 243 459 6.6E-18 T 28-03-2018 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 Pfam PF07690 Major Facilitator Superfamily 19 276 9.2E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 SUPERFAMILY SSF103473 239 455 6.67E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS04205 abb07ca312e94e2f5a6fb89dc464a236 459 SUPERFAMILY SSF103473 7 194 6.67E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 Hamap MF_00942 Endonuclease III [nth]. 1 211 38.012 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 SMART SM00525 188 208 2.5E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 1.6E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 SMART SM00478 39 187 4.1E-58 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 167 1.2E-22 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 189 205 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 Pfam PF00633 Helix-hairpin-helix motif 101 128 1.6E-7 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 Gene3D G3DSA:1.10.1670.10 119 219 1.5E-33 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 Gene3D G3DSA:1.10.340.30 22 118 3.1E-27 T 28-03-2018 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 SUPERFAMILY SSF48150 1 211 1.49E-71 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 PIRSF PIRSF001435 1 213 9.0E-58 T 28-03-2018 CWR44_RS10230 e156be28f17e9ac9a257967ca366575f 219 TIGRFAM TIGR01083 nth: endonuclease III 4 196 4.5E-83 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CWR44_RS06065 f9c2f836a6f5cfadf23b57ca77475b5a 254 SMART SM00422 7 76 2.7E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS06065 f9c2f836a6f5cfadf23b57ca77475b5a 254 Gene3D G3DSA:1.10.490.50 165 254 5.7E-10 T 28-03-2018 CWR44_RS06065 f9c2f836a6f5cfadf23b57ca77475b5a 254 Pfam PF13411 MerR HTH family regulatory protein 8 75 3.9E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS06065 f9c2f836a6f5cfadf23b57ca77475b5a 254 SUPERFAMILY SSF46955 7 109 7.33E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain CWR44_RS06065 f9c2f836a6f5cfadf23b57ca77475b5a 254 SUPERFAMILY SSF89082 166 254 1.44E-19 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CWR44_RS06065 f9c2f836a6f5cfadf23b57ca77475b5a 254 Gene3D G3DSA:1.10.1660.10 3 62 1.3E-20 T 28-03-2018 CWR44_RS06065 f9c2f836a6f5cfadf23b57ca77475b5a 254 Pfam PF07739 TipAS antibiotic-recognition domain 131 252 5.5E-13 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CWR44_RS06065 f9c2f836a6f5cfadf23b57ca77475b5a 254 Gene3D G3DSA:1.10.1660.10 63 138 3.0E-6 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 SUPERFAMILY SSF55424 325 438 1.22E-28 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 Gene3D G3DSA:3.50.50.60 141 262 5.9E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.0E-50 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 3.0E-50 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 125 134 3.0E-50 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 390 405 3.0E-50 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 325 346 3.0E-50 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 412 432 3.0E-50 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 162 187 3.0E-50 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 246 260 3.0E-50 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 288 295 3.0E-50 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 SUPERFAMILY SSF51905 1 301 3.28E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 297 3.6E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 329 435 6.1E-21 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 122 140 2.0E-32 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 245 261 2.0E-32 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 295 2.0E-32 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.0E-32 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 2.0E-32 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 Gene3D G3DSA:3.50.50.60 1 140 1.4E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 Gene3D G3DSA:3.50.50.60 263 305 1.3E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 Gene3D G3DSA:3.30.390.30 328 439 8.5E-27 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PIRSF PIRSF000350 61 436 3.3E-70 T 28-03-2018 CWR44_RS05965 a8974546dd3f7ccdfbc22d09c88f1ca2 440 PIRSF PIRSF000350 1 59 3.5E-10 T 28-03-2018 CWR44_RS11825 68d1f488e4902ccdae5339430507c8a2 78 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 2 70 24.85 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWR44_RS11825 68d1f488e4902ccdae5339430507c8a2 78 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 69 9.0E-25 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWR44_RS11825 68d1f488e4902ccdae5339430507c8a2 78 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 76 1.6E-31 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWR44_RS11825 68d1f488e4902ccdae5339430507c8a2 78 SMART SM01234 2 69 1.6E-45 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWR44_RS11825 68d1f488e4902ccdae5339430507c8a2 78 Pfam PF01809 Haemolytic domain 3 69 1.4E-30 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 SMART SM00448 3 116 3.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 Gene3D G3DSA:3.40.50.2300 2 127 2.6E-33 T 28-03-2018 CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 Pfam PF00072 Response regulator receiver domain 5 116 2.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 Gene3D G3DSA:1.10.10.10 128 209 1.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 SMART SM00421 145 202 2.1E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 4.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 4.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 4.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 4.8E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 SUPERFAMILY SSF46894 132 208 9.52E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS12300 97d8b11592bbbe321a76c1850ea3ca2a 209 SUPERFAMILY SSF52172 2 130 4.84E-33 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 Gene3D G3DSA:1.10.10.10 1 64 2.5E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 Pfam PF03099 Biotin/lipoate A/B protein ligase family 88 212 2.2E-13 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 84 321 3.6E-60 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 Pfam PF08279 HTH domain 6 59 1.5E-13 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 SUPERFAMILY SSF55681 73 274 4.89E-57 T 28-03-2018 CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 7 323 30.828 T 28-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 Gene3D G3DSA:2.30.30.100 278 321 4.1E-10 T 28-03-2018 CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 SUPERFAMILY SSF50037 281 322 6.41E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 SUPERFAMILY SSF46785 7 60 4.47E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 Pfam PF02237 Biotin protein ligase C terminal domain 283 322 4.0E-5 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CWR44_RS10250 668b895b72fe939f0742995a9f93f6b7 323 Gene3D G3DSA:3.30.930.10 67 276 4.3E-60 T 28-03-2018 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 286 1.2E-144 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 Gene3D G3DSA:3.40.50.261 120 299 4.4E-54 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 PIRSF PIRSF001553 1 291 1.5E-131 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 Gene3D G3DSA:3.40.50.720 1 119 2.7E-43 T 28-03-2018 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.3E-39 T 28-03-2018 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.3E-39 T 28-03-2018 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.3E-39 T 28-03-2018 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.3E-39 T 28-03-2018 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 SMART SM00881 4 100 6.8E-32 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 SUPERFAMILY SSF51735 1 122 4.93E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 Pfam PF02629 CoA binding domain 6 99 8.8E-30 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 SUPERFAMILY SSF52210 123 285 2.09E-54 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 Pfam PF00549 CoA-ligase 151 266 4.4E-18 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR44_RS08645 eeabee742a6990fcce22895574311e8d 301 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 42.761 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CWR44_RS07040 9b2f9a6c9e31dc5d2f6eb21cb61ef2bb 67 Pfam PF06855 YozE SAM-like fold 2 65 3.5E-18 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS07040 9b2f9a6c9e31dc5d2f6eb21cb61ef2bb 67 Gene3D G3DSA:1.10.150.260 1 66 1.2E-20 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS07040 9b2f9a6c9e31dc5d2f6eb21cb61ef2bb 67 SUPERFAMILY SSF140652 1 65 6.93E-21 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS04330 eaa5bdb425592b9a22bb1b2dec6b713d 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.703 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS04330 eaa5bdb425592b9a22bb1b2dec6b713d 159 Gene3D G3DSA:3.40.1280.10 1 159 3.5E-64 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR44_RS04330 eaa5bdb425592b9a22bb1b2dec6b713d 159 SUPERFAMILY SSF75217 1 157 1.05E-58 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR44_RS04330 eaa5bdb425592b9a22bb1b2dec6b713d 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 2.6E-57 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS04330 eaa5bdb425592b9a22bb1b2dec6b713d 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 4.7E-61 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS04330 eaa5bdb425592b9a22bb1b2dec6b713d 159 PIRSF PIRSF004505 1 159 3.1E-54 T 28-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS06085 7983e249332aff0b9cd679ddffb4b5db 234 SUPERFAMILY SSF56784 4 224 2.36E-38 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS06085 7983e249332aff0b9cd679ddffb4b5db 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 75 190 3.0E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS06085 7983e249332aff0b9cd679ddffb4b5db 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 3.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS06085 7983e249332aff0b9cd679ddffb4b5db 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 177 3.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS06085 7983e249332aff0b9cd679ddffb4b5db 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 3.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS06085 7983e249332aff0b9cd679ddffb4b5db 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 3.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS06085 7983e249332aff0b9cd679ddffb4b5db 234 Gene3D G3DSA:3.40.50.1000 76 232 9.3E-27 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS06085 7983e249332aff0b9cd679ddffb4b5db 234 Gene3D G3DSA:3.40.50.1000 1 45 0.035 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS06085 7983e249332aff0b9cd679ddffb4b5db 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 145 195 3.1E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS06085 7983e249332aff0b9cd679ddffb4b5db 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 195 2.1E-28 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS05670 fd0593ef8161387b88aa607261b2b044 388 PIRSF PIRSF005962 3 386 2.8E-124 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS05670 fd0593ef8161387b88aa607261b2b044 388 Pfam PF07687 Peptidase dimerisation domain 187 279 3.8E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS05670 fd0593ef8161387b88aa607261b2b044 388 Pfam PF01546 Peptidase family M20/M25/M40 73 368 3.9E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS05670 fd0593ef8161387b88aa607261b2b044 388 Gene3D G3DSA:3.40.630.10 3 245 1.4E-47 T 28-03-2018 CWR44_RS05670 fd0593ef8161387b88aa607261b2b044 388 Gene3D G3DSA:3.40.630.10 249 383 1.3E-15 T 28-03-2018 CWR44_RS05670 fd0593ef8161387b88aa607261b2b044 388 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 373 1.1E-112 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS05670 fd0593ef8161387b88aa607261b2b044 388 SUPERFAMILY SSF55031 185 296 1.83E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS05670 fd0593ef8161387b88aa607261b2b044 388 SUPERFAMILY SSF53187 299 380 1.02E-80 T 28-03-2018 CWR44_RS05670 fd0593ef8161387b88aa607261b2b044 388 SUPERFAMILY SSF53187 5 198 1.02E-80 T 28-03-2018 CWR44_RS08540 bf0dcfb5a10898321a7485805520c18e 266 SMART SM00318 56 190 1.3E-35 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CWR44_RS08540 bf0dcfb5a10898321a7485805520c18e 266 ProSitePatterns PS01123 Thermonuclease family signature 1. 67 91 - T 28-03-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 CWR44_RS08540 bf0dcfb5a10898321a7485805520c18e 266 SMART SM00894 229 265 5.6E-18 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CWR44_RS08540 bf0dcfb5a10898321a7485805520c18e 266 ProSitePatterns PS01284 Thermonuclease family signature 2. 131 141 - T 28-03-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 CWR44_RS08540 bf0dcfb5a10898321a7485805520c18e 266 Pfam PF05901 Excalibur calcium-binding domain 230 265 2.7E-15 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CWR44_RS08540 bf0dcfb5a10898321a7485805520c18e 266 Pfam PF00565 Staphylococcal nuclease homologue 81 189 4.6E-31 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CWR44_RS08540 bf0dcfb5a10898321a7485805520c18e 266 Gene3D G3DSA:2.40.50.90 50 197 7.5E-35 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CWR44_RS08540 bf0dcfb5a10898321a7485805520c18e 266 SUPERFAMILY SSF50199 65 190 2.75E-32 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CWR44_RS07510 923586aa2669003ae631bd12718d5fb1 240 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 230 3.0E-49 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CWR44_RS07510 923586aa2669003ae631bd12718d5fb1 240 PIRSF PIRSF029008 1 237 9.5E-70 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CWR44_RS07510 923586aa2669003ae631bd12718d5fb1 240 Hamap MF_01124 Adapter protein MecA [mecA]. 1 235 25.284 T 28-03-2018 IPR008681 Negative regulator of genetic competence, MecA CWR44_RS07215 845d7b962d7a8046187b06bc90697f55 321 Gene3D G3DSA:3.40.50.720 115 290 1.6E-52 T 28-03-2018 CWR44_RS07215 845d7b962d7a8046187b06bc90697f55 321 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CWR44_RS07215 845d7b962d7a8046187b06bc90697f55 321 Gene3D G3DSA:3.40.50.720 1 114 1.4E-32 T 28-03-2018 CWR44_RS07215 845d7b962d7a8046187b06bc90697f55 321 SUPERFAMILY SSF51735 101 288 2.23E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS07215 845d7b962d7a8046187b06bc90697f55 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 287 9.4E-63 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWR44_RS07215 845d7b962d7a8046187b06bc90697f55 321 SUPERFAMILY SSF52283 3 134 1.66E-34 T 28-03-2018 CWR44_RS07215 845d7b962d7a8046187b06bc90697f55 321 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 317 3.1E-31 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CWR44_RS12580 a7dc010cc874c6ba390a0f93b6eadce8 205 Gene3D G3DSA:2.60.40.1240 85 203 3.9E-14 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CWR44_RS12580 a7dc010cc874c6ba390a0f93b6eadce8 205 Pfam PF11611 Domain of unknown function (DUF4352) 86 196 6.8E-10 T 28-03-2018 IPR029051 Domain of unknown function DUF4352 CWR44_RS04810 122a6fcf6548c42a5a817655b2531d98 219 Gene3D G3DSA:3.30.460.10 14 169 6.7E-17 T 28-03-2018 CWR44_RS04810 122a6fcf6548c42a5a817655b2531d98 219 SUPERFAMILY SSF81301 19 157 9.16E-15 T 28-03-2018 CWR44_RS04810 122a6fcf6548c42a5a817655b2531d98 219 Pfam PF01909 Nucleotidyltransferase domain 29 87 2.8E-5 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CWR44_RS10465 1780f2ca9cf7b5a630a843e952c6f443 548 SMART SM00642 13 415 1.1E-152 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR44_RS10465 1780f2ca9cf7b5a630a843e952c6f443 548 Pfam PF00128 Alpha amylase, catalytic domain 28 372 9.5E-114 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR44_RS10465 1780f2ca9cf7b5a630a843e952c6f443 548 PRINTS PR00110 Alpha-amylase signature 92 103 1.8E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CWR44_RS10465 1780f2ca9cf7b5a630a843e952c6f443 548 PRINTS PR00110 Alpha-amylase signature 194 205 1.8E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CWR44_RS10465 1780f2ca9cf7b5a630a843e952c6f443 548 PRINTS PR00110 Alpha-amylase signature 316 328 1.8E-5 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CWR44_RS10465 1780f2ca9cf7b5a630a843e952c6f443 548 SUPERFAMILY SSF51011 476 546 1.87E-13 T 28-03-2018 CWR44_RS10465 1780f2ca9cf7b5a630a843e952c6f443 548 Gene3D G3DSA:3.20.20.80 2 476 9.4E-123 T 28-03-2018 CWR44_RS10465 1780f2ca9cf7b5a630a843e952c6f443 548 SUPERFAMILY SSF51445 4 471 3.31E-147 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWR44_RS10465 1780f2ca9cf7b5a630a843e952c6f443 548 Pfam PF16657 Maltogenic Amylase, C-terminal domain 476 520 3.0E-8 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal CWR44_RS10465 1780f2ca9cf7b5a630a843e952c6f443 548 Gene3D G3DSA:2.60.40.1180 477 545 2.3E-15 T 28-03-2018 CWR44_RS09105 f567217fd2a2dfa5f68375c1e7ef8689 144 SUPERFAMILY SSF88659 79 135 1.81E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS09105 f567217fd2a2dfa5f68375c1e7ef8689 144 TIGRFAM TIGR01636 phage_rinA: phage transcriptional regulator, RinA family 8 143 1.1E-21 T 28-03-2018 IPR006523 Transcription activator RinA CWR44_RS09105 f567217fd2a2dfa5f68375c1e7ef8689 144 Gene3D G3DSA:1.10.10.10 18 140 1.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS08235 46617ebecfba09e4b192e126c57384e0 266 Gene3D G3DSA:3.40.50.1860 113 266 2.0E-40 T 28-03-2018 CWR44_RS08235 46617ebecfba09e4b192e126c57384e0 266 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 69 77 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS08235 46617ebecfba09e4b192e126c57384e0 266 SUPERFAMILY SSF53681 4 106 5.36E-36 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS08235 46617ebecfba09e4b192e126c57384e0 266 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 254 8.5E-80 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS08235 46617ebecfba09e4b192e126c57384e0 266 Hamap MF_00258 Glutamate racemase [murI]. 3 256 38.661 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS08235 46617ebecfba09e4b192e126c57384e0 266 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 180 190 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS08235 46617ebecfba09e4b192e126c57384e0 266 Gene3D G3DSA:3.40.50.1860 1 112 8.2E-29 T 28-03-2018 CWR44_RS08235 46617ebecfba09e4b192e126c57384e0 266 SUPERFAMILY SSF53681 108 261 1.98E-37 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS08235 46617ebecfba09e4b192e126c57384e0 266 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 215 3.7E-35 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS11075 6184a8e9d65cf5a11294a4fc17f1c8f9 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.002 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CWR44_RS11075 6184a8e9d65cf5a11294a4fc17f1c8f9 172 Pfam PF00156 Phosphoribosyl transferase domain 36 149 6.7E-15 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR44_RS11075 6184a8e9d65cf5a11294a4fc17f1c8f9 172 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 5.5E-69 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CWR44_RS11075 6184a8e9d65cf5a11294a4fc17f1c8f9 172 SUPERFAMILY SSF53271 3 164 4.83E-51 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWR44_RS11075 6184a8e9d65cf5a11294a4fc17f1c8f9 172 Gene3D G3DSA:3.40.50.2020 1 172 6.8E-40 T 28-03-2018 CWR44_RS08855 8760ad96792591dddb1097d1ce7295f2 586 SUPERFAMILY SSF52922 473 582 3.61E-19 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR44_RS08855 8760ad96792591dddb1097d1ce7295f2 586 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 210 453 8.6E-65 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CWR44_RS08855 8760ad96792591dddb1097d1ce7295f2 586 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 476 547 1.6E-7 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CWR44_RS08855 8760ad96792591dddb1097d1ce7295f2 586 Gene3D G3DSA:3.40.920.10 1 182 1.4E-42 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR44_RS08855 8760ad96792591dddb1097d1ce7295f2 586 SUPERFAMILY SSF52518 198 458 1.92E-73 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS08855 8760ad96792591dddb1097d1ce7295f2 586 Gene3D G3DSA:3.40.50.970 195 484 1.5E-62 T 28-03-2018 CWR44_RS08855 8760ad96792591dddb1097d1ce7295f2 586 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 174 2.6E-41 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CWR44_RS08855 8760ad96792591dddb1097d1ce7295f2 586 SUPERFAMILY SSF53323 2 221 1.03E-41 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CWR44_RS08855 8760ad96792591dddb1097d1ce7295f2 586 Gene3D G3DSA:3.40.50.920 485 581 3.0E-11 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR44_RS08855 8760ad96792591dddb1097d1ce7295f2 586 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 573 3.5E-211 T 28-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CWR44_RS07865 6b82f7611648425f2b171c53d14e6405 188 SUPERFAMILY SSF53328 3 186 1.18E-53 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR44_RS07865 6b82f7611648425f2b171c53d14e6405 188 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 26.496 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CWR44_RS07865 6b82f7611648425f2b171c53d14e6405 188 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 187 2.1E-63 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CWR44_RS07865 6b82f7611648425f2b171c53d14e6405 188 Gene3D G3DSA:3.40.50.170 1 188 1.8E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR44_RS07865 6b82f7611648425f2b171c53d14e6405 188 Pfam PF00551 Formyl transferase 3 183 9.8E-55 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR44_RS03140 2389a1e7e3252744c1095c86dd29ed23 320 Pfam PF12368 Rhodanase C-terminal 220 285 2.6E-15 T 28-03-2018 IPR022111 Rhodanase, C-terminal CWR44_RS03140 2389a1e7e3252744c1095c86dd29ed23 320 Pfam PF00581 Rhodanese-like domain 114 208 7.6E-11 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS03140 2389a1e7e3252744c1095c86dd29ed23 320 SUPERFAMILY SSF52821 86 244 2.74E-33 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS03140 2389a1e7e3252744c1095c86dd29ed23 320 Hamap MF_00469 UPF0176 protein YceA [yceA]. 1 265 39.447 T 28-03-2018 IPR020936 Uncharacterised protein family UPF0176 CWR44_RS03140 2389a1e7e3252744c1095c86dd29ed23 320 Gene3D G3DSA:3.40.250.10 107 262 4.4E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS03140 2389a1e7e3252744c1095c86dd29ed23 320 SMART SM00450 113 214 8.8E-19 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS08675 ec1f20df84208b64bff411cd9af1a49e 181 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 9 181 3.5E-82 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CWR44_RS08675 ec1f20df84208b64bff411cd9af1a49e 181 SUPERFAMILY SSF56235 6 181 3.46E-57 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS08675 ec1f20df84208b64bff411cd9af1a49e 181 PIRSF PIRSF039093 2 181 4.7E-85 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CWR44_RS08675 ec1f20df84208b64bff411cd9af1a49e 181 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 8 181 40.213 T 28-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CWR44_RS08675 ec1f20df84208b64bff411cd9af1a49e 181 Pfam PF00227 Proteasome subunit 7 180 5.8E-26 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CWR44_RS08675 ec1f20df84208b64bff411cd9af1a49e 181 Gene3D G3DSA:3.60.20.10 9 181 1.8E-27 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS05110 9d06f5bbde2ceba1d94214b719b0d052 176 Pfam PF13599 Pentapeptide repeats (9 copies) 52 124 4.1E-8 T 28-03-2018 IPR001646 Pentapeptide repeat CWR44_RS05110 9d06f5bbde2ceba1d94214b719b0d052 176 Gene3D G3DSA:2.160.10.20 96 176 5.9E-9 T 28-03-2018 CWR44_RS05110 9d06f5bbde2ceba1d94214b719b0d052 176 SUPERFAMILY SSF141571 4 164 1.18E-19 T 28-03-2018 CWR44_RS05110 9d06f5bbde2ceba1d94214b719b0d052 176 Gene3D G3DSA:2.160.10.20 1 95 3.0E-8 T 28-03-2018 CWR44_RS07580 336a978afcc3e87e8cdfa99791740f9d 254 Gene3D G3DSA:3.40.50.1820 2 253 1.3E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS07580 336a978afcc3e87e8cdfa99791740f9d 254 Pfam PF00756 Putative esterase 16 239 1.0E-49 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CWR44_RS07580 336a978afcc3e87e8cdfa99791740f9d 254 SUPERFAMILY SSF53474 4 240 8.72E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS10970 cc8e7279f998b7c2ee7fa352c74d0562 211 Pfam PF01596 O-methyltransferase 34 207 6.2E-30 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CWR44_RS10970 cc8e7279f998b7c2ee7fa352c74d0562 211 Gene3D G3DSA:3.40.50.150 1 211 1.1E-34 T 28-03-2018 CWR44_RS10970 cc8e7279f998b7c2ee7fa352c74d0562 211 SUPERFAMILY SSF53335 5 207 4.56E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 127 377 1.2E-18 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 5 418 4.1E-135 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 SUPERFAMILY SSF50621 261 419 1.78E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 79 91 8.6E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 276 295 8.6E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 191 204 8.6E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 59 77 8.6E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 377 390 8.6E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 420 40.039 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 Gene3D G3DSA:2.40.37.10 271 421 1.8E-40 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 223 239 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 Gene3D G3DSA:3.20.20.10 34 270 1.9E-62 T 28-03-2018 IPR029066 PLP-binding barrel CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 163 172 5.6E-22 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 387 409 5.6E-22 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 77 94 5.6E-22 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 PRINTS PR01181 Diaminopimelate decarboxylase signature 305 323 5.6E-22 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 SUPERFAMILY SSF51419 26 288 6.83E-75 T 28-03-2018 IPR029066 PLP-binding barrel CWR44_RS09995 9f139b9f994b6de276669daed56b5cb4 421 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 286 2.3E-60 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CWR44_RS00850 aa417420f3c417966a84e9023b2924b3 419 SUPERFAMILY SSF55729 1 153 1.96E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS00850 aa417420f3c417966a84e9023b2924b3 419 SUPERFAMILY SSF55729 300 398 1.29E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS00850 aa417420f3c417966a84e9023b2924b3 419 SUPERFAMILY SSF55729 155 235 1.29E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS00850 aa417420f3c417966a84e9023b2924b3 419 Gene3D G3DSA:3.40.630.30 158 379 5.3E-31 T 28-03-2018 CWR44_RS00850 aa417420f3c417966a84e9023b2924b3 419 Gene3D G3DSA:3.40.630.30 1 157 6.5E-41 T 28-03-2018 CWR44_RS00850 aa417420f3c417966a84e9023b2924b3 419 Pfam PF02388 FemAB family 6 401 3.5E-81 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CWR44_RS07225 430dac7f37acbf4d4eef550ea9a544cd 485 Gene3D G3DSA:3.40.50.980 2 144 2.0E-26 T 28-03-2018 CWR44_RS07225 430dac7f37acbf4d4eef550ea9a544cd 485 Gene3D G3DSA:2.30.38.10 299 380 9.7E-11 T 28-03-2018 CWR44_RS07225 430dac7f37acbf4d4eef550ea9a544cd 485 Pfam PF00501 AMP-binding enzyme 13 386 1.3E-68 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CWR44_RS07225 430dac7f37acbf4d4eef550ea9a544cd 485 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 485 218.442 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CWR44_RS07225 430dac7f37acbf4d4eef550ea9a544cd 485 Gene3D G3DSA:3.40.50.980 145 298 2.0E-32 T 28-03-2018 CWR44_RS07225 430dac7f37acbf4d4eef550ea9a544cd 485 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 3 484 1.1E-205 T 28-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CWR44_RS07225 430dac7f37acbf4d4eef550ea9a544cd 485 Pfam PF13193 AMP-binding enzyme C-terminal domain 395 473 6.7E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CWR44_RS07225 430dac7f37acbf4d4eef550ea9a544cd 485 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 29 411 6.1E-97 T 28-03-2018 IPR010071 Amino acid adenylation domain CWR44_RS07225 430dac7f37acbf4d4eef550ea9a544cd 485 SUPERFAMILY SSF56801 4 482 2.88E-112 T 28-03-2018 CWR44_RS07225 430dac7f37acbf4d4eef550ea9a544cd 485 Gene3D G3DSA:3.30.300.30 381 485 1.1E-27 T 28-03-2018 CWR44_RS12520 175b3725d6d47a114b7f15740253a9c5 571 Gene3D G3DSA:3.90.350.10 260 498 2.1E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS12520 175b3725d6d47a114b7f15740253a9c5 571 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS12520 175b3725d6d47a114b7f15740253a9c5 571 Pfam PF01609 Transposase DDE domain 264 515 9.0E-38 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS06940 1f35187c0963ef27fe20bfc8a3e8fa4e 505 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 504 48.814 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06940 1f35187c0963ef27fe20bfc8a3e8fa4e 505 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 293 9.4E-84 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06940 1f35187c0963ef27fe20bfc8a3e8fa4e 505 SUPERFAMILY SSF64158 77 303 9.42E-86 T 28-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06940 1f35187c0963ef27fe20bfc8a3e8fa4e 505 PIRSF PIRSF001492 1 505 4.1E-202 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06940 1f35187c0963ef27fe20bfc8a3e8fa4e 505 Gene3D G3DSA:3.40.720.10 452 505 2.1E-4 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWR44_RS06940 1f35187c0963ef27fe20bfc8a3e8fa4e 505 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 503 8.8E-210 T 28-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06940 1f35187c0963ef27fe20bfc8a3e8fa4e 505 SUPERFAMILY SSF53649 305 503 3.81E-72 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR44_RS06940 1f35187c0963ef27fe20bfc8a3e8fa4e 505 SUPERFAMILY SSF53649 5 77 3.81E-72 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR44_RS06940 1f35187c0963ef27fe20bfc8a3e8fa4e 505 Pfam PF01676 Metalloenzyme superfamily 5 492 6.7E-75 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CWR44_RS06940 1f35187c0963ef27fe20bfc8a3e8fa4e 505 Gene3D G3DSA:3.40.1450.10 77 306 3.7E-95 T 28-03-2018 CWR44_RS13155 2b6ee0c572ad5d9a7fbf8847df5d538c 313 Pfam PF01545 Cation efflux family 18 211 1.3E-48 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR44_RS13155 2b6ee0c572ad5d9a7fbf8847df5d538c 313 SUPERFAMILY SSF160240 215 291 1.44E-12 T 28-03-2018 CWR44_RS13155 2b6ee0c572ad5d9a7fbf8847df5d538c 313 SUPERFAMILY SSF161111 13 212 3.92E-57 T 28-03-2018 CWR44_RS13155 2b6ee0c572ad5d9a7fbf8847df5d538c 313 Gene3D G3DSA:1.20.1510.10 13 209 2.2E-57 T 28-03-2018 CWR44_RS13155 2b6ee0c572ad5d9a7fbf8847df5d538c 313 Gene3D G3DSA:3.30.70.1350 210 294 3.0E-16 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR44_RS13155 2b6ee0c572ad5d9a7fbf8847df5d538c 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 14 293 2.6E-93 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 SUPERFAMILY SSF158832 6 309 1.44E-105 T 28-03-2018 CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 Gene3D G3DSA:1.10.150.310 487 621 1.3E-43 T 28-03-2018 CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 SUPERFAMILY SSF47781 549 623 4.45E-18 T 28-03-2018 IPR010994 RuvA domain 2-like CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 SUPERFAMILY SSF53098 310 457 6.07E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 Gene3D G3DSA:1.10.3500.10 346 486 1.9E-40 T 28-03-2018 IPR023323 Tex-like domain CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 Pfam PF00575 S1 RNA binding domain 639 710 4.3E-17 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 Pfam PF12836 Helix-hairpin-helix motif 479 543 8.6E-25 T 28-03-2018 CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 Gene3D G3DSA:2.40.50.140 631 713 1.3E-23 T 28-03-2018 CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 Gene3D G3DSA:1.10.3500.10 103 345 4.4E-80 T 28-03-2018 IPR023323 Tex-like domain CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 Pfam PF09371 Tex-like protein N-terminal domain 10 189 1.9E-63 T 28-03-2018 IPR018974 Tex-like protein, N-terminal CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 Pfam PF16921 Tex protein YqgF-like domain 314 439 6.3E-54 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 SUPERFAMILY SSF50249 628 710 6.86E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 SUPERFAMILY SSF47781 458 544 3.56E-25 T 28-03-2018 IPR010994 RuvA domain 2-like CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 SMART SM00732 314 412 9.0E-33 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 SMART SM00316 640 711 6.4E-23 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS12800 8404cc66f3a97bc2f22dcf2dc26178c8 715 Gene3D G3DSA:1.10.10.650 2 102 9.3E-31 T 28-03-2018 IPR023319 Tex-like protein, HTH domain CWR44_RS02840 d3b6050327685a49eb72a186f538a2bf 227 SUPERFAMILY SSF51206 32 155 8.25E-22 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CWR44_RS02840 d3b6050327685a49eb72a186f538a2bf 227 Gene3D G3DSA:1.10.10.10 157 227 3.5E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02840 d3b6050327685a49eb72a186f538a2bf 227 SUPERFAMILY SSF46785 159 226 5.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02840 d3b6050327685a49eb72a186f538a2bf 227 Pfam PF00027 Cyclic nucleotide-binding domain 42 128 6.4E-7 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CWR44_RS02840 d3b6050327685a49eb72a186f538a2bf 227 Gene3D G3DSA:2.60.120.10 15 156 3.1E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 Pfam PF00072 Response regulator receiver domain 3 115 3.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 SUPERFAMILY SSF52172 2 126 4.27E-29 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 Gene3D G3DSA:1.10.10.10 127 217 4.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 SUPERFAMILY SSF46894 139 215 6.12E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 Gene3D G3DSA:3.40.50.2300 1 126 2.3E-29 T 28-03-2018 CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 SMART SM00448 1 115 5.0E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 5.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 5.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 5.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 SMART SM00421 152 209 2.1E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS01480 fd84ee1cfe2d209e46d3943e23156eaa 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 2.9E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS00935 78d968a481e703536c0dd2381593cb5c 264 Pfam PF13531 Bacterial extracellular solute-binding protein 46 262 5.3E-41 T 28-03-2018 CWR44_RS00935 78d968a481e703536c0dd2381593cb5c 264 Gene3D G3DSA:3.40.190.10 137 228 1.8E-28 T 28-03-2018 CWR44_RS00935 78d968a481e703536c0dd2381593cb5c 264 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 51 260 5.5E-58 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CWR44_RS00935 78d968a481e703536c0dd2381593cb5c 264 PIRSF PIRSF004846 1 264 1.3E-78 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CWR44_RS00935 78d968a481e703536c0dd2381593cb5c 264 Gene3D G3DSA:3.40.190.10 44 136 6.6E-16 T 28-03-2018 CWR44_RS00935 78d968a481e703536c0dd2381593cb5c 264 SUPERFAMILY SSF53850 44 263 8.37E-56 T 28-03-2018 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 SUPERFAMILY SSF88946 96 205 1.31E-53 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 Gene3D G3DSA:1.10.601.10 79 204 1.3E-74 T 28-03-2018 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 Gene3D G3DSA:1.10.601.10 2 78 0.0054 T 28-03-2018 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 SUPERFAMILY SSF88659 208 281 5.79E-22 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 13 368 33.831 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 159 172 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 Pfam PF04539 Sigma-70 region 3 214 290 2.1E-31 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 Gene3D G3DSA:1.10.10.10 297 368 4.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 Gene3D G3DSA:1.10.10.10 205 255 8.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 Pfam PF00140 Sigma-70 factor, region 1.2 97 129 1.6E-18 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 Pfam PF03979 Sigma-70 factor, region 1.1 24 81 9.8E-16 T 28-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 328 354 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 Pfam PF04545 Sigma-70, region 4 303 356 5.0E-20 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 PRINTS PR00046 Major sigma-70 factor signature 307 319 2.9E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 PRINTS PR00046 Major sigma-70 factor signature 343 354 2.9E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 PRINTS PR00046 Major sigma-70 factor signature 328 343 2.9E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 PRINTS PR00046 Major sigma-70 factor signature 159 172 2.9E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 PRINTS PR00046 Major sigma-70 factor signature 183 191 2.9E-32 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 SUPERFAMILY SSF88659 265 366 4.49E-30 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 131 367 5.8E-124 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 133 356 6.9E-39 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10730 c77e87c2370a1737b92f9c33169c8239 368 Pfam PF04542 Sigma-70 region 2 135 204 4.2E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 Pfam PF00012 Hsp70 protein 76 574 8.5E-223 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 Gene3D G3DSA:2.60.34.10 360 501 6.6E-67 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 574 1.6E-285 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 Gene3D G3DSA:3.30.420.40 1 170 4.3E-69 T 28-03-2018 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 SUPERFAMILY SSF53067 1 157 4.32E-57 T 28-03-2018 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 Gene3D G3DSA:3.30.420.40 171 331 3.8E-49 T 28-03-2018 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 SUPERFAMILY SSF100920 354 510 5.1E-61 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 PRINTS PR00301 70kDa heat shock protein signature 53 61 7.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 PRINTS PR00301 70kDa heat shock protein signature 304 320 7.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 PRINTS PR00301 70kDa heat shock protein signature 358 377 7.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 PRINTS PR00301 70kDa heat shock protein signature 439 455 7.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 PRINTS PR00301 70kDa heat shock protein signature 172 182 7.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 PRINTS PR00301 70kDa heat shock protein signature 3 16 7.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 PRINTS PR00301 70kDa heat shock protein signature 31 43 7.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 PRINTS PR00301 70kDa heat shock protein signature 112 132 7.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 PRINTS PR00301 70kDa heat shock protein signature 335 355 7.7E-78 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 Gene3D G3DSA:1.20.1270.10 502 589 2.3E-24 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 SUPERFAMILY SSF53067 161 351 1.18E-66 T 28-03-2018 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 604 37.066 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CWR44_RS10825 e940a12ac267b7a4926aa836c98be907 611 SUPERFAMILY SSF100934 477 575 1.26E-14 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 44 55 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 SUPERFAMILY SSF46589 810 874 1.2E-17 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 16 559 1.7E-213 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 SUPERFAMILY SSF47323 571 825 5.98E-73 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 Gene3D G3DSA:1.10.287.380 803 873 4.7E-27 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 SUPERFAMILY SSF50677 191 342 3.66E-62 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 Hamap MF_02004 Valine--tRNA ligase [valS]. 3 875 15.907 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 Gene3D G3DSA:1.10.730.10 518 743 2.6E-74 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 Gene3D G3DSA:3.40.50.620 433 517 7.9E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 SUPERFAMILY SSF52374 341 570 3.15E-142 T 28-03-2018 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 SUPERFAMILY SSF52374 2 193 3.15E-142 T 28-03-2018 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 857 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 Gene3D G3DSA:3.90.740.10 237 432 5.8E-61 T 28-03-2018 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 Gene3D G3DSA:3.90.740.10 190 236 7.3E-15 T 28-03-2018 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 810 875 8.6E-23 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 Gene3D G3DSA:3.40.50.620 17 189 1.5E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 Pfam PF08264 Anticodon-binding domain of tRNA 604 751 3.3E-42 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 PRINTS PR00986 Valyl-tRNA synthetase signature 346 359 5.8E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 5.8E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 PRINTS PR00986 Valyl-tRNA synthetase signature 37 48 5.8E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 PRINTS PR00986 Valyl-tRNA synthetase signature 472 490 5.8E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR44_RS11185 d028d7e994f532093d7461ecb576f28a 876 PRINTS PR00986 Valyl-tRNA synthetase signature 440 461 5.8E-38 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 SUPERFAMILY SSF52540 191 510 4.5E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 SUPERFAMILY SSF52540 566 745 1.42E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 SUPERFAMILY SSF52540 461 528 1.42E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 9 755 28.884 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 Gene3D G3DSA:3.40.50.300 523 734 5.0E-28 T 28-03-2018 CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 Pfam PF14490 Helix-hairpin-helix containing domain 153 243 4.2E-30 T 28-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 Gene3D G3DSA:1.10.150.280 81 158 3.3E-5 T 28-03-2018 CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 Gene3D G3DSA:3.40.50.300 262 522 2.5E-33 T 28-03-2018 CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 Pfam PF13538 UvrD-like helicase C-terminal domain 673 720 1.7E-15 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 SMART SM00382 353 513 9.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 Gene3D G3DSA:1.10.150.20 166 217 0.1 T 28-03-2018 CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 Pfam PF13604 AAA domain 340 545 4.3E-53 T 28-03-2018 CWR44_RS10995 e2aa2b23c4133e5d66f2a5d732ddcbf5 812 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 12 746 0.0 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CWR44_RS06245 e19d0dd137496e30f47f1b3000cdbe27 575 Pfam PF00005 ABC transporter 351 501 2.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06245 e19d0dd137496e30f47f1b3000cdbe27 575 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS06245 e19d0dd137496e30f47f1b3000cdbe27 575 Pfam PF00664 ABC transporter transmembrane region 22 289 1.5E-50 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR44_RS06245 e19d0dd137496e30f47f1b3000cdbe27 575 SMART SM00382 360 547 3.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS06245 e19d0dd137496e30f47f1b3000cdbe27 575 SUPERFAMILY SSF52540 331 571 6.48E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06245 e19d0dd137496e30f47f1b3000cdbe27 575 Gene3D G3DSA:1.20.1560.10 3 321 2.2E-71 T 28-03-2018 CWR44_RS06245 e19d0dd137496e30f47f1b3000cdbe27 575 SUPERFAMILY SSF90123 10 319 1.96E-75 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR44_RS06245 e19d0dd137496e30f47f1b3000cdbe27 575 Gene3D G3DSA:3.40.50.300 322 575 1.1E-72 T 28-03-2018 CWR44_RS08320 211a535981e3f0e99590c7c9afcdd462 449 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 12 443 4.0E-122 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS08320 211a535981e3f0e99590c7c9afcdd462 449 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 445 34.094 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS08320 211a535981e3f0e99590c7c9afcdd462 449 SUPERFAMILY SSF51984 7 98 7.19E-15 T 28-03-2018 CWR44_RS08320 211a535981e3f0e99590c7c9afcdd462 449 Pfam PF02875 Mur ligase family, glutamate ligase domain 309 375 2.2E-8 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR44_RS08320 211a535981e3f0e99590c7c9afcdd462 449 SUPERFAMILY SSF53623 102 305 1.28E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS08320 211a535981e3f0e99590c7c9afcdd462 449 SUPERFAMILY SSF53244 307 443 2.61E-40 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR44_RS08320 211a535981e3f0e99590c7c9afcdd462 449 Pfam PF08245 Mur ligase middle domain 116 287 1.7E-33 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS08320 211a535981e3f0e99590c7c9afcdd462 449 Gene3D G3DSA:3.40.1190.10 101 305 6.2E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS08320 211a535981e3f0e99590c7c9afcdd462 449 Gene3D G3DSA:3.90.190.20 312 444 1.8E-33 T 28-03-2018 CWR44_RS08320 211a535981e3f0e99590c7c9afcdd462 449 Gene3D G3DSA:3.40.50.720 3 100 2.0E-13 T 28-03-2018 CWR44_RS08215 ff51932909bf8de3e5b00d2b409beb89 204 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 7 204 1.4E-44 T 28-03-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit CWR44_RS08215 ff51932909bf8de3e5b00d2b409beb89 204 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 92 191 2.4E-11 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS08215 ff51932909bf8de3e5b00d2b409beb89 204 PIRSF PIRSF000170 2 204 2.1E-93 T 28-03-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute CWR44_RS08215 ff51932909bf8de3e5b00d2b409beb89 204 Gene3D G3DSA:1.20.1300.10 1 204 1.2E-46 T 28-03-2018 CWR44_RS08215 ff51932909bf8de3e5b00d2b409beb89 204 SUPERFAMILY SSF81343 2 203 4.32E-57 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS02150 0df4b99d64b4bb59bc245c572ed53a6f 350 SUPERFAMILY SSF50129 1 156 1.17E-52 T 28-03-2018 IPR011032 GroES-like CWR44_RS02150 0df4b99d64b4bb59bc245c572ed53a6f 350 Gene3D G3DSA:3.40.50.10730 169 333 1.4E-28 T 28-03-2018 CWR44_RS02150 0df4b99d64b4bb59bc245c572ed53a6f 350 Gene3D G3DSA:3.90.180.10 1 168 1.1E-47 T 28-03-2018 CWR44_RS02150 0df4b99d64b4bb59bc245c572ed53a6f 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 129 9.9E-31 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWR44_RS02150 0df4b99d64b4bb59bc245c572ed53a6f 350 SMART SM00829 10 344 0.0018 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR44_RS02150 0df4b99d64b4bb59bc245c572ed53a6f 350 SUPERFAMILY SSF51735 140 309 8.65E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02150 0df4b99d64b4bb59bc245c572ed53a6f 350 Pfam PF00107 Zinc-binding dehydrogenase 178 304 7.8E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR44_RS02150 0df4b99d64b4bb59bc245c572ed53a6f 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 Gene3D G3DSA:3.30.1330.20 215 323 2.2E-47 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 329 4.2E-137 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 PRINTS PR00423 Cell division protein FtsZ signature 126 147 2.4E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 PRINTS PR00423 Cell division protein FtsZ signature 189 211 2.4E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 PRINTS PR00423 Cell division protein FtsZ signature 212 233 2.4E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 PRINTS PR00423 Cell division protein FtsZ signature 98 118 2.4E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 Pfam PF12327 FtsZ family, C-terminal domain 222 316 7.2E-34 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 SMART SM00865 207 324 1.9E-57 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 Gene3D G3DSA:3.40.50.1440 9 214 3.9E-47 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 SUPERFAMILY SSF52490 13 208 3.53E-71 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 SUPERFAMILY SSF55307 207 318 3.2E-44 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 2.5E-45 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 SMART SM00864 13 205 9.9E-116 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CWR44_RS08335 a0280e4040f7f2ec8576a5c42e9b2b29 393 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 368 38.896 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CWR44_RS08345 fe082c9ba75bfee900e7d924339ca086 222 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 222 4.1E-46 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CWR44_RS08345 fe082c9ba75bfee900e7d924339ca086 222 Pfam PF01168 Alanine racemase, N-terminal domain 26 221 9.8E-16 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS08345 fe082c9ba75bfee900e7d924339ca086 222 PIRSF PIRSF004848 1 222 2.7E-60 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CWR44_RS08345 fe082c9ba75bfee900e7d924339ca086 222 SUPERFAMILY SSF51419 1 221 6.8E-68 T 28-03-2018 IPR029066 PLP-binding barrel CWR44_RS08345 fe082c9ba75bfee900e7d924339ca086 222 Gene3D G3DSA:3.20.20.10 1 222 1.6E-44 T 28-03-2018 IPR029066 PLP-binding barrel CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 Gene3D G3DSA:3.30.565.10 411 564 3.3E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 454 561 2.9E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 Pfam PF08448 PAS fold 231 336 5.4E-7 T 28-03-2018 IPR013656 PAS fold-4 CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 SUPERFAMILY SSF47384 327 407 7.46E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 SMART SM00091 225 290 3.4E-4 T 28-03-2018 IPR000014 PAS domain CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 SUPERFAMILY SSF55785 214 333 1.47E-9 T 28-03-2018 IPR000014 PAS domain CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 542 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 517 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 561 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 503 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 SMART SM00388 341 408 1.5E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 Gene3D G3DSA:1.10.287.130 347 404 1.8E-17 T 28-03-2018 CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 Pfam PF00512 His Kinase A (phospho-acceptor) domain 342 407 1.1E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 Gene3D G3DSA:3.30.450.20 223 346 1.5E-18 T 28-03-2018 CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 SUPERFAMILY SSF55874 398 560 1.44E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS11320 df4a433010f16935a2a64b7d83fa8078 565 SMART SM00387 452 564 1.6E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS12275 219ba3f9c81eccc72b4ecdd2e367926d 415 SUPERFAMILY SSF144052 6 414 1.83E-143 T 28-03-2018 CWR44_RS12275 219ba3f9c81eccc72b4ecdd2e367926d 415 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 368 390 1.1E-52 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR44_RS12275 219ba3f9c81eccc72b4ecdd2e367926d 415 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 250 269 1.1E-52 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR44_RS12275 219ba3f9c81eccc72b4ecdd2e367926d 415 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 306 326 1.1E-52 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR44_RS12275 219ba3f9c81eccc72b4ecdd2e367926d 415 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 160 182 1.1E-52 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR44_RS12275 219ba3f9c81eccc72b4ecdd2e367926d 415 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 329 350 1.1E-52 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR44_RS12275 219ba3f9c81eccc72b4ecdd2e367926d 415 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 394 413 1.1E-52 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR44_RS12275 219ba3f9c81eccc72b4ecdd2e367926d 415 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 17 34 1.1E-52 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR44_RS12275 219ba3f9c81eccc72b4ecdd2e367926d 415 Gene3D G3DSA:3.40.1830.10 7 179 3.2E-53 T 28-03-2018 IPR035097 Peptidase M29, N-terminal CWR44_RS12275 219ba3f9c81eccc72b4ecdd2e367926d 415 Pfam PF02073 Thermophilic metalloprotease (M29) 7 413 1.9E-160 T 28-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CWR44_RS08775 a978b832f75e744ca964b590bca434f1 89 Pfam PF00312 Ribosomal protein S15 8 88 4.9E-38 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08775 a978b832f75e744ca964b590bca434f1 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08775 a978b832f75e744ca964b590bca434f1 89 SMART SM01387 8 88 4.3E-52 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08775 a978b832f75e744ca964b590bca434f1 89 Gene3D G3DSA:1.10.287.10 2 89 1.2E-36 T 28-03-2018 CWR44_RS08775 a978b832f75e744ca964b590bca434f1 89 SUPERFAMILY SSF47060 3 89 7.06E-37 T 28-03-2018 IPR009068 S15/NS1, RNA-binding CWR44_RS08775 a978b832f75e744ca964b590bca434f1 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.812 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08775 a978b832f75e744ca964b590bca434f1 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 1.0E-40 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08775 a978b832f75e744ca964b590bca434f1 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 5.0E-39 T 28-03-2018 CWR44_RS03940 aabee467d532b4b9d99bd67762213e2c 456 PRINTS PR01774 Exfoliative toxin signature 271 295 1.7E-5 T 28-03-2018 IPR008353 Peptidase S1B, exfoliative toxin GO:0004252|GO:0006508 CWR44_RS03940 aabee467d532b4b9d99bd67762213e2c 456 PRINTS PR01774 Exfoliative toxin signature 399 423 1.7E-5 T 28-03-2018 IPR008353 Peptidase S1B, exfoliative toxin GO:0004252|GO:0006508 CWR44_RS03940 aabee467d532b4b9d99bd67762213e2c 456 Gene3D G3DSA:2.40.10.10 367 453 3.9E-10 T 28-03-2018 CWR44_RS03940 aabee467d532b4b9d99bd67762213e2c 456 Gene3D G3DSA:2.40.10.10 215 343 4.3E-5 T 28-03-2018 CWR44_RS03940 aabee467d532b4b9d99bd67762213e2c 456 SUPERFAMILY SSF50494 234 438 5.31E-22 T 28-03-2018 IPR009003 Peptidase S1, PA clan CWR44_RS03940 aabee467d532b4b9d99bd67762213e2c 456 Pfam PF00089 Trypsin 264 437 8.3E-8 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CWR44_RS06540 6946d733db385501f8a274fbf2e5d266 458 Gene3D G3DSA:3.30.465.10 346 430 3.8E-17 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWR44_RS06540 6946d733db385501f8a274fbf2e5d266 458 SUPERFAMILY SSF54631 206 341 5.94E-28 T 28-03-2018 CWR44_RS06540 6946d733db385501f8a274fbf2e5d266 458 Gene3D G3DSA:3.10.580.10 197 345 4.0E-30 T 28-03-2018 CWR44_RS06540 6946d733db385501f8a274fbf2e5d266 458 Pfam PF01595 Domain of unknown function DUF21 11 203 1.3E-51 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CWR44_RS06540 6946d733db385501f8a274fbf2e5d266 458 Pfam PF00571 CBS domain 289 338 2.0E-5 T 28-03-2018 IPR000644 CBS domain CWR44_RS06540 6946d733db385501f8a274fbf2e5d266 458 Pfam PF00571 CBS domain 219 273 1.9E-4 T 28-03-2018 IPR000644 CBS domain CWR44_RS06540 6946d733db385501f8a274fbf2e5d266 458 SUPERFAMILY SSF56176 352 430 3.82E-14 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWR44_RS06540 6946d733db385501f8a274fbf2e5d266 458 Pfam PF03471 Transporter associated domain 355 429 5.3E-14 T 28-03-2018 IPR005170 Transporter-associated domain CWR44_RS06540 6946d733db385501f8a274fbf2e5d266 458 SMART SM01091 354 432 3.7E-15 T 28-03-2018 IPR005170 Transporter-associated domain CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 SUPERFAMILY SSF51905 1 304 2.54E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 304 3.1E-120 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 293 6.2E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 Gene3D G3DSA:3.50.50.60 128 174 1.9E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 3.4E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 3.4E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 40 55 3.4E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 3.4E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 3.4E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 3.4E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 194 210 3.4E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 267 285 3.4E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 233 254 3.4E-69 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 Gene3D G3DSA:3.50.50.60 175 312 5.6E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 Gene3D G3DSA:3.50.50.60 1 127 2.2E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 3.2E-38 T 28-03-2018 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 3.2E-38 T 28-03-2018 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 3.2E-38 T 28-03-2018 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 3.2E-38 T 28-03-2018 CWR44_RS06865 943aa405bade26ced5f1e035c79c76a9 313 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 3.2E-38 T 28-03-2018 CWR44_RS11020 2e19a6eadceaf81e8b122d1e804127ad 390 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS11020 2e19a6eadceaf81e8b122d1e804127ad 390 Pfam PF00872 Transposase, Mutator family 1 380 3.8E-167 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS11020 2e19a6eadceaf81e8b122d1e804127ad 390 Gene3D G3DSA:3.30.420.10 159 377 0.0014 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS04745 2e19a6eadceaf81e8b122d1e804127ad 390 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS04745 2e19a6eadceaf81e8b122d1e804127ad 390 Pfam PF00872 Transposase, Mutator family 1 380 3.8E-167 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS04745 2e19a6eadceaf81e8b122d1e804127ad 390 Gene3D G3DSA:3.30.420.10 159 377 0.0014 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS04730 2e19a6eadceaf81e8b122d1e804127ad 390 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS04730 2e19a6eadceaf81e8b122d1e804127ad 390 Pfam PF00872 Transposase, Mutator family 1 380 3.8E-167 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS04730 2e19a6eadceaf81e8b122d1e804127ad 390 Gene3D G3DSA:3.30.420.10 159 377 0.0014 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS07015 2e19a6eadceaf81e8b122d1e804127ad 390 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS07015 2e19a6eadceaf81e8b122d1e804127ad 390 Pfam PF00872 Transposase, Mutator family 1 380 3.8E-167 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS07015 2e19a6eadceaf81e8b122d1e804127ad 390 Gene3D G3DSA:3.30.420.10 159 377 0.0014 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS05790 2e19a6eadceaf81e8b122d1e804127ad 390 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS05790 2e19a6eadceaf81e8b122d1e804127ad 390 Pfam PF00872 Transposase, Mutator family 1 380 3.8E-167 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS05790 2e19a6eadceaf81e8b122d1e804127ad 390 Gene3D G3DSA:3.30.420.10 159 377 0.0014 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 560 6.2E-113 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 SUPERFAMILY SSF55681 117 298 6.57E-111 T 28-03-2018 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 SUPERFAMILY SSF55681 427 587 6.57E-111 T 28-03-2018 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 SUPERFAMILY SSF55261 295 422 1.96E-40 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 SUPERFAMILY SSF50249 4 108 1.47E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 2.5E-18 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 Gene3D G3DSA:3.30.930.10 370 588 5.5E-56 T 28-03-2018 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 Gene3D G3DSA:3.30.930.10 137 358 1.1E-57 T 28-03-2018 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 585 4.3E-257 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 587 34.957 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 Gene3D G3DSA:2.40.50.140 1 111 1.0E-27 T 28-03-2018 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 208 5.8E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 521 535 5.8E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 213 226 5.8E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 477 493 5.8E-27 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11050 0fc2cc3d5317478854f70bcd33c15631 588 Pfam PF02938 GAD domain 314 408 9.3E-29 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CWR44_RS00350 50e97d4603fb19fb6afe90ee6f4686bf 310 SUPERFAMILY SSF51182 2 310 3.8E-95 T 28-03-2018 IPR011051 RmlC-like cupin domain CWR44_RS00350 50e97d4603fb19fb6afe90ee6f4686bf 310 Pfam PF01238 Phosphomannose isomerase type I 4 193 2.8E-28 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CWR44_RS00350 50e97d4603fb19fb6afe90ee6f4686bf 310 Gene3D G3DSA:2.60.120.10 230 310 8.5E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWR44_RS00350 50e97d4603fb19fb6afe90ee6f4686bf 310 Gene3D G3DSA:2.60.120.10 1 218 3.9E-53 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWR44_RS00350 50e97d4603fb19fb6afe90ee6f4686bf 310 PIRSF PIRSF036894 1 310 1.3E-117 T 28-03-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 Gene3D G3DSA:1.10.10.60 144 193 1.3E-11 T 28-03-2018 CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 SUPERFAMILY SSF46689 190 238 1.88E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 Pfam PF12833 Helix-turn-helix domain 161 236 5.1E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 Pfam PF02311 AraC-like ligand binding domain 2 116 7.4E-6 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 206 221 7.8E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 221 237 7.8E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 Gene3D G3DSA:1.10.10.60 194 242 6.2E-10 T 28-03-2018 CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 SUPERFAMILY SSF51182 2 59 1.11E-6 T 28-03-2018 IPR011051 RmlC-like cupin domain CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 SMART SM00342 154 237 1.5E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 SUPERFAMILY SSF46689 137 188 8.36E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 Gene3D G3DSA:2.60.120.10 1 143 5.9E-6 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWR44_RS02115 65b50d7301854b3a92b6bb89a3c246b5 245 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 191 233 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR44_RS10815 96535ae8578af4dba4ea44a121433d81 312 Gene3D G3DSA:3.40.50.150 114 312 1.1E-39 T 28-03-2018 CWR44_RS10815 96535ae8578af4dba4ea44a121433d81 312 PIRSF PIRSF000401 1 311 4.5E-112 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CWR44_RS10815 96535ae8578af4dba4ea44a121433d81 312 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 309 34.114 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CWR44_RS10815 96535ae8578af4dba4ea44a121433d81 312 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 303 1.1E-78 T 28-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CWR44_RS10815 96535ae8578af4dba4ea44a121433d81 312 SUPERFAMILY SSF53335 54 308 1.92E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS10815 96535ae8578af4dba4ea44a121433d81 312 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 309 8.3E-105 T 28-03-2018 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 290 2.6E-67 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 Gene3D G3DSA:3.30.470.20 185 319 3.9E-50 T 28-03-2018 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 Gene3D G3DSA:3.30.1490.20 86 183 6.8E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 284 291 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 SMART SM01210 322 411 1.7E-35 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 SUPERFAMILY SSF56059 103 307 1.35E-51 T 28-03-2018 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 Gene3D G3DSA:3.90.600.10 322 411 1.1E-25 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 411 37.643 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 SUPERFAMILY SSF52440 1 102 2.16E-32 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 2.4E-32 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 SMART SM01209 102 290 1.4E-109 T 28-03-2018 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 411 4.6E-141 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 Gene3D G3DSA:3.40.50.20 2 85 4.2E-33 T 28-03-2018 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 324 409 2.5E-23 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR44_RS07875 16fd7ff1298228f5e86e2d7bbea7a6e9 413 SUPERFAMILY SSF51246 321 411 3.3E-24 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 SUPERFAMILY SSF47413 2 60 5.96E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 1.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 1.5E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 4.4E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 Gene3D G3DSA:1.10.260.40 3 55 8.6E-24 T 28-03-2018 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 SMART SM00354 2 72 8.2E-39 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 SUPERFAMILY SSF53822 62 329 4.89E-69 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 Pfam PF13377 Periplasmic binding protein-like domain 169 328 1.5E-26 T 28-03-2018 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 Gene3D G3DSA:3.40.50.2300 56 175 3.5E-31 T 28-03-2018 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 Gene3D G3DSA:3.40.50.2300 176 311 1.0E-29 T 28-03-2018 CWR44_RS11550 be11df8cb5d69b7f26eec3b6c7bd7a44 330 TIGRFAM TIGR01481 ccpA: catabolite control protein A 1 329 8.7E-165 T 28-03-2018 IPR006377 Catabolite control protein A GO:0006355 CWR44_RS12360 c02f90d8f8964142bda6f54d68b1ee00 358 Gene3D G3DSA:3.30.70.270 121 172 6.2E-18 T 28-03-2018 CWR44_RS12360 c02f90d8f8964142bda6f54d68b1ee00 358 Gene3D G3DSA:3.30.70.270 43 120 8.9E-27 T 28-03-2018 CWR44_RS12360 c02f90d8f8964142bda6f54d68b1ee00 358 SUPERFAMILY SSF56672 3 236 1.78E-89 T 28-03-2018 CWR44_RS12360 c02f90d8f8964142bda6f54d68b1ee00 358 Pfam PF00817 impB/mucB/samB family 9 155 9.3E-52 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR44_RS12360 c02f90d8f8964142bda6f54d68b1ee00 358 SUPERFAMILY SSF100879 240 341 1.35E-25 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR44_RS12360 c02f90d8f8964142bda6f54d68b1ee00 358 Hamap MF_01113 DNA polymerase IV [dinB]. 3 352 36.965 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CWR44_RS12360 c02f90d8f8964142bda6f54d68b1ee00 358 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 344 9.2E-20 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR44_RS12360 c02f90d8f8964142bda6f54d68b1ee00 358 Gene3D G3DSA:1.10.150.20 173 245 1.0E-14 T 28-03-2018 CWR44_RS12360 c02f90d8f8964142bda6f54d68b1ee00 358 Gene3D G3DSA:3.30.1490.100 246 351 2.6E-27 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CWR44_RS07120 42b9ac8867a6d9193addb35e05d70f8e 271 Gene3D G3DSA:3.40.190.10 30 123 3.4E-26 T 28-03-2018 CWR44_RS07120 42b9ac8867a6d9193addb35e05d70f8e 271 Pfam PF03180 NLPA lipoprotein 31 270 1.4E-85 T 28-03-2018 IPR004872 Lipoprotein NlpA family CWR44_RS07120 42b9ac8867a6d9193addb35e05d70f8e 271 SUPERFAMILY SSF53850 30 270 2.4E-77 T 28-03-2018 CWR44_RS07120 42b9ac8867a6d9193addb35e05d70f8e 271 Gene3D G3DSA:3.40.190.10 124 270 3.0E-45 T 28-03-2018 CWR44_RS07120 42b9ac8867a6d9193addb35e05d70f8e 271 PIRSF PIRSF002854 1 271 3.1E-96 T 28-03-2018 IPR004872 Lipoprotein NlpA family CWR44_RS00265 021ea8ce5282ea7cf2f8cba570926fc7 535 Gene3D G3DSA:3.40.50.300 1 287 2.6E-131 T 28-03-2018 CWR44_RS00265 021ea8ce5282ea7cf2f8cba570926fc7 535 SUPERFAMILY SSF52317 292 534 2.58E-83 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS00265 021ea8ce5282ea7cf2f8cba570926fc7 535 Pfam PF06418 CTP synthase N-terminus 3 267 1.3E-127 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CWR44_RS00265 021ea8ce5282ea7cf2f8cba570926fc7 535 TIGRFAM TIGR00337 PyrG: CTP synthase 1 528 1.1E-255 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CWR44_RS00265 021ea8ce5282ea7cf2f8cba570926fc7 535 SUPERFAMILY SSF52540 1 269 1.93E-124 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00265 021ea8ce5282ea7cf2f8cba570926fc7 535 Hamap MF_01227 CTP synthase [pyrG]. 2 533 52.573 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CWR44_RS00265 021ea8ce5282ea7cf2f8cba570926fc7 535 Pfam PF00117 Glutamine amidotransferase class-I 303 528 7.7E-56 T 28-03-2018 IPR017926 Glutamine amidotransferase CWR44_RS00265 021ea8ce5282ea7cf2f8cba570926fc7 535 Gene3D G3DSA:3.40.50.880 289 535 9.9E-74 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 PIRSF PIRSF000726 53 400 3.5E-90 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 PIRSF PIRSF000726 2 61 9.9E-13 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 Pfam PF13840 ACT domain 333 395 7.9E-8 T 28-03-2018 IPR027795 GATS-like ACT domain CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 Gene3D G3DSA:3.30.70.260 333 399 7.5E-12 T 28-03-2018 CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 SUPERFAMILY SSF55021 333 399 2.86E-13 T 28-03-2018 CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 Pfam PF00696 Amino acid kinase family 2 227 6.1E-40 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 Gene3D G3DSA:3.40.1160.10 1 235 1.7E-52 T 28-03-2018 CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 SUPERFAMILY SSF55021 248 322 1.37E-8 T 28-03-2018 CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 62 398 1.2E-91 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 SUPERFAMILY SSF53633 3 241 9.69E-59 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR44_RS09960 32a89ae2d5426718381abb43ed7ea91d 400 Gene3D G3DSA:3.30.70.260 236 332 1.2E-11 T 28-03-2018 CWR44_RS01715 076ae2b61f25c4cc5c63e3623d530435 256 SUPERFAMILY SSF52172 2 127 5.41E-31 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS01715 076ae2b61f25c4cc5c63e3623d530435 256 SMART SM00850 157 254 2.1E-27 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR44_RS01715 076ae2b61f25c4cc5c63e3623d530435 256 Pfam PF00072 Response regulator receiver domain 4 113 9.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS01715 076ae2b61f25c4cc5c63e3623d530435 256 Gene3D G3DSA:2.40.50.40 147 217 2.1E-13 T 28-03-2018 CWR44_RS01715 076ae2b61f25c4cc5c63e3623d530435 256 SMART SM00448 1 112 3.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS01715 076ae2b61f25c4cc5c63e3623d530435 256 Gene3D G3DSA:3.40.50.2300 1 134 1.5E-28 T 28-03-2018 CWR44_RS01715 076ae2b61f25c4cc5c63e3623d530435 256 Gene3D G3DSA:2.20.25.10 218 254 7.9E-11 T 28-03-2018 CWR44_RS01715 076ae2b61f25c4cc5c63e3623d530435 256 Pfam PF04397 LytTr DNA-binding domain 158 251 1.4E-23 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR44_RS06920 aaca734ac14a31a952d6d20b2cca2ff0 337 Gene3D G3DSA:1.10.10.10 19 87 8.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06920 aaca734ac14a31a952d6d20b2cca2ff0 337 SUPERFAMILY SSF46785 19 84 4.34E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06920 aaca734ac14a31a952d6d20b2cca2ff0 337 Gene3D G3DSA:3.40.50.1360 91 336 1.4E-32 T 28-03-2018 CWR44_RS06920 aaca734ac14a31a952d6d20b2cca2ff0 337 SUPERFAMILY SSF100950 96 337 1.09E-64 T 28-03-2018 CWR44_RS06920 aaca734ac14a31a952d6d20b2cca2ff0 337 Pfam PF04198 Putative sugar-binding domain 92 337 1.2E-69 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CWR44_RS01305 74973e53c5575f22f2f33397b5cf8895 224 Gene3D G3DSA:3.40.50.2300 1 121 4.0E-33 T 28-03-2018 CWR44_RS01305 74973e53c5575f22f2f33397b5cf8895 224 Pfam PF00072 Response regulator receiver domain 5 112 4.6E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS01305 74973e53c5575f22f2f33397b5cf8895 224 SMART SM00862 145 220 6.7E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS01305 74973e53c5575f22f2f33397b5cf8895 224 SMART SM00448 2 112 5.5E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS01305 74973e53c5575f22f2f33397b5cf8895 224 Gene3D G3DSA:1.10.10.10 122 223 5.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01305 74973e53c5575f22f2f33397b5cf8895 224 SUPERFAMILY SSF52172 1 175 1.3E-38 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS01305 74973e53c5575f22f2f33397b5cf8895 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 3.9E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS08805 772663f96b0b7226906936af918d5e2f 429 Pfam PF00675 Insulinase (Peptidase family M16) 64 170 1.5E-15 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CWR44_RS08805 772663f96b0b7226906936af918d5e2f 429 Gene3D G3DSA:3.30.830.10 7 223 3.1E-45 T 28-03-2018 CWR44_RS08805 772663f96b0b7226906936af918d5e2f 429 SUPERFAMILY SSF63411 249 421 4.19E-18 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR44_RS08805 772663f96b0b7226906936af918d5e2f 429 Gene3D G3DSA:3.30.830.10 224 425 1.8E-20 T 28-03-2018 CWR44_RS08805 772663f96b0b7226906936af918d5e2f 429 SUPERFAMILY SSF63411 13 221 1.83E-40 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR44_RS08805 772663f96b0b7226906936af918d5e2f 429 Pfam PF05193 Peptidase M16 inactive domain 182 363 7.2E-22 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 SUPERFAMILY SSF46600 187 239 7.98E-12 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 10 573 5.1E-196 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 Pfam PF02151 UvrB/uvrC motif 201 234 1.1E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 Gene3D G3DSA:4.10.860.10 179 239 5.8E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 SMART SM00465 19 99 7.1E-25 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 SUPERFAMILY SSF47781 507 594 8.58E-16 T 28-03-2018 IPR010994 RuvA domain 2-like CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 Hamap MF_00203 UvrABC system protein C [uvrC]. 6 592 28.304 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 SUPERFAMILY SSF82771 20 101 2.35E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 Gene3D G3DSA:3.40.1440.10 5 102 2.0E-25 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 378 528 1.8E-51 T 28-03-2018 IPR001162 UvrC family homology region CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 Gene3D G3DSA:1.10.150.20 527 596 4.3E-9 T 28-03-2018 CWR44_RS08210 71f63ffc5e3ddaa54f9026d7bddc82ec 596 Pfam PF01541 GIY-YIG catalytic domain 20 94 6.5E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR44_RS10395 a4ba090f79c2bb6e21baa07e072d6cbb 245 Pfam PF01479 S4 domain 6 52 9.5E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS10395 a4ba090f79c2bb6e21baa07e072d6cbb 245 SUPERFAMILY SSF55174 6 71 1.04E-14 T 28-03-2018 CWR44_RS10395 a4ba090f79c2bb6e21baa07e072d6cbb 245 SMART SM00363 6 63 9.2E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS10395 a4ba090f79c2bb6e21baa07e072d6cbb 245 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 103 117 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWR44_RS10395 a4ba090f79c2bb6e21baa07e072d6cbb 245 SUPERFAMILY SSF55120 50 240 2.64E-44 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS10395 a4ba090f79c2bb6e21baa07e072d6cbb 245 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 70 230 1.7E-50 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWR44_RS10395 a4ba090f79c2bb6e21baa07e072d6cbb 245 Gene3D G3DSA:3.10.290.10 3 61 8.6E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS10395 a4ba090f79c2bb6e21baa07e072d6cbb 245 Gene3D G3DSA:3.30.70.1560 147 217 5.7E-23 T 28-03-2018 CWR44_RS10395 a4ba090f79c2bb6e21baa07e072d6cbb 245 Gene3D G3DSA:3.30.70.580 62 146 6.4E-21 T 28-03-2018 CWR44_RS10395 a4ba090f79c2bb6e21baa07e072d6cbb 245 Pfam PF00849 RNA pseudouridylate synthase 66 200 9.7E-23 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS05840 1604eaabd289ff9a21f3460688cd48ff 221 Gene3D G3DSA:3.40.50.10320 2 211 2.0E-41 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CWR44_RS05840 1604eaabd289ff9a21f3460688cd48ff 221 SUPERFAMILY SSF102588 4 218 4.19E-48 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CWR44_RS05840 1604eaabd289ff9a21f3460688cd48ff 221 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 136 3.9E-27 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CWR44_RS05840 1604eaabd289ff9a21f3460688cd48ff 221 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 5 219 4.8E-102 T 28-03-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 SUPERFAMILY SSF81338 3 234 4.84E-72 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 Pfam PF00230 Major intrinsic protein 4 230 7.0E-43 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 230 1.9E-59 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 ProSitePatterns PS00221 MIP family signature. 62 70 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 PRINTS PR00783 Major intrinsic protein family signature 81 100 3.0E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 PRINTS PR00783 Major intrinsic protein family signature 44 68 3.0E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 PRINTS PR00783 Major intrinsic protein family signature 166 188 3.0E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 PRINTS PR00783 Major intrinsic protein family signature 2 21 3.0E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 PRINTS PR00783 Major intrinsic protein family signature 213 233 3.0E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 PRINTS PR00783 Major intrinsic protein family signature 136 154 3.0E-42 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CWR44_RS08905 0fdfacd216dbe8ac0016106b3541a84b 272 Gene3D G3DSA:1.20.1080.10 1 239 7.2E-84 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CWR44_RS11115 cacac2e63465a662910be0e9afc1e44a 151 Gene3D G3DSA:3.30.70.260 73 150 2.8E-11 T 28-03-2018 CWR44_RS11115 cacac2e63465a662910be0e9afc1e44a 151 Hamap MF_00707 UPF0735 ACT domain-containing protein . 5 150 27.978 T 28-03-2018 IPR008310 UPF0735 ACT domain-containing protein CWR44_RS11115 cacac2e63465a662910be0e9afc1e44a 151 SUPERFAMILY SSF55021 72 147 2.21E-9 T 28-03-2018 CWR44_RS11115 cacac2e63465a662910be0e9afc1e44a 151 PIRSF PIRSF025624 1 150 9.7E-61 T 28-03-2018 IPR008310 UPF0735 ACT domain-containing protein CWR44_RS07340 9305c8e1d0db3b363245dd9eaba539c7 126 Gene3D G3DSA:2.40.50.140 2 16 0.48 T 28-03-2018 CWR44_RS07340 9305c8e1d0db3b363245dd9eaba539c7 126 SUPERFAMILY SSF50249 4 77 1.94E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS07340 9305c8e1d0db3b363245dd9eaba539c7 126 Pfam PF00575 S1 RNA binding domain 6 76 4.6E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS07340 9305c8e1d0db3b363245dd9eaba539c7 126 Gene3D G3DSA:2.40.50.140 17 107 3.3E-24 T 28-03-2018 CWR44_RS07340 9305c8e1d0db3b363245dd9eaba539c7 126 SMART SM00316 6 76 5.0E-22 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS00255 d870b3bde5dc99b98f2f373b211cc449 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR44_RS00255 d870b3bde5dc99b98f2f373b211cc449 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 284 6.1E-128 T 28-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CWR44_RS00255 d870b3bde5dc99b98f2f373b211cc449 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 283 1.5E-101 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR44_RS00255 d870b3bde5dc99b98f2f373b211cc449 285 Gene3D G3DSA:3.20.20.70 1 285 6.5E-106 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS00255 d870b3bde5dc99b98f2f373b211cc449 285 PIRSF PIRSF001359 1 284 2.4E-127 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR44_RS00255 d870b3bde5dc99b98f2f373b211cc449 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 284 9.1E-115 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CWR44_RS00255 d870b3bde5dc99b98f2f373b211cc449 285 SUPERFAMILY SSF51569 1 284 2.34E-104 T 28-03-2018 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 SMART SM00836 435 553 3.4E-57 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 Gene3D G3DSA:3.40.50.620 107 361 2.0E-57 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 Pfam PF05746 DALR anticodon binding domain 436 553 8.6E-38 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 553 27.112 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 SMART SM01016 9 93 5.7E-35 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 8 553 5.7E-157 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 Gene3D G3DSA:3.30.1360.70 3 106 3.3E-33 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 SUPERFAMILY SSF52374 119 446 1.26E-95 T 28-03-2018 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 10 93 3.6E-26 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 SUPERFAMILY SSF55190 5 113 1.83E-27 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 Gene3D G3DSA:1.10.730.10 401 553 1.2E-47 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 Pfam PF00750 tRNA synthetases class I (R) 105 409 2.4E-26 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 SUPERFAMILY SSF47323 430 553 3.01E-37 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 2.7E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 2.7E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 2.7E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR44_RS06055 0b139a7297891fdb24e18306c0016ac0 553 PRINTS PR01038 Arginyl-tRNA synthetase signature 304 325 2.7E-24 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 SUPERFAMILY SSF56601 25 281 1.01E-71 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 57 74 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 159 184 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 133 157 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 212 227 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 26 50 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 97 122 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 PRINTS PR00118 Beta-lactamase class A signature 195 210 1.3E-47 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 Gene3D G3DSA:3.40.710.10 24 281 1.9E-38 T 28-03-2018 CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 Pfam PF13354 Beta-lactamase enzyme family 46 246 8.3E-37 T 28-03-2018 CWR44_RS04795 38f49897d465bec66fbf5f7c7bc7ea6b 281 ProSitePatterns PS00146 Beta-lactamase class-A active site. 59 74 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 SUPERFAMILY SSF46600 613 659 2.22E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 7 658 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 SUPERFAMILY SSF52540 6 416 1.38E-145 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 Pfam PF00271 Helicase conserved C-terminal domain 436 546 1.1E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 Gene3D G3DSA:4.10.860.10 602 661 3.5E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 Gene3D G3DSA:3.40.50.300 12 416 2.2E-33 T 28-03-2018 CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 Pfam PF04851 Type III restriction enzyme, res subunit 14 140 3.2E-12 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 SMART SM00487 11 427 3.9E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 Hamap MF_00204 UvrABC system protein B [uvrB]. 5 660 44.45 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 Gene3D G3DSA:3.40.50.300 417 590 4.1E-33 T 28-03-2018 CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 Pfam PF02151 UvrB/uvrC motif 626 659 1.2E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 Pfam PF12344 Ultra-violet resistance protein B 553 594 4.3E-22 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 SUPERFAMILY SSF52540 34 82 4.54E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 SUPERFAMILY SSF52540 471 595 4.54E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06835 d5857f40fd99499ac29ca1bec7d378cc 661 SMART SM00490 461 547 3.6E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Gene3D G3DSA:3.40.50.300 554 830 3.8E-44 T 28-03-2018 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Pfam PF01624 MutS domain I 5 115 9.2E-49 T 28-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 5 796 0.0 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Gene3D G3DSA:1.10.1420.10 247 390 1.1E-35 T 28-03-2018 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 SUPERFAMILY SSF55271 2 112 7.32E-46 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 SUPERFAMILY SSF48334 251 553 4.19E-86 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Pfam PF05192 MutS domain III 256 546 1.6E-43 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Gene3D G3DSA:3.30.420.110 129 245 8.0E-21 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 874 25.136 T 28-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Gene3D G3DSA:3.40.1170.10 1 128 3.3E-50 T 28-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 PIRSF PIRSF037677 1 239 1.1E-37 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 PIRSF PIRSF037677 170 860 1.5E-135 T 28-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Pfam PF05190 MutS family domain IV 412 505 4.7E-26 T 28-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 676 692 - T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Gene3D G3DSA:1.10.1420.10 391 522 4.5E-27 T 28-03-2018 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 SUPERFAMILY SSF53150 114 264 4.71E-35 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 SMART SM00534 595 782 2.9E-110 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Pfam PF00488 MutS domain V 599 784 4.9E-83 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 Pfam PF05188 MutS domain II 125 237 3.5E-12 T 28-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 SUPERFAMILY SSF52540 554 786 1.41E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08890 c9f1f2081470084a2f15253858c1bcb6 883 SMART SM00533 268 578 8.4E-107 T 28-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CWR44_RS09285 9da1d47c7d1fb5a873967690d82740de 288 SUPERFAMILY SSF52540 2 215 5.33E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS09285 9da1d47c7d1fb5a873967690d82740de 288 ProSitePatterns PS00211 ABC transporters family signature. 123 137 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS09285 9da1d47c7d1fb5a873967690d82740de 288 Pfam PF00005 ABC transporter 17 150 8.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS09285 9da1d47c7d1fb5a873967690d82740de 288 SMART SM00382 26 199 3.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS09285 9da1d47c7d1fb5a873967690d82740de 288 Gene3D G3DSA:3.40.50.300 1 257 9.3E-50 T 28-03-2018 CWR44_RS01360 29c0dab961a54d3f0d4d129c02e2624b 581 Gene3D G3DSA:1.20.120.20 200 323 8.9E-5 T 28-03-2018 CWR44_RS01360 29c0dab961a54d3f0d4d129c02e2624b 581 Pfam PF03239 Iron permease FTR1 family 298 490 3.0E-22 T 28-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 208 228 8.3E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 275 293 8.3E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 Gene3D G3DSA:3.40.50.300 238 384 4.4E-14 T 28-03-2018 CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 Hamap MF_00900 GTPase HflX [hflX]. 35 394 42.798 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 Pfam PF16360 GTP-binding GTPase Middle Region 122 200 1.5E-31 T 28-03-2018 IPR032305 GTP-binding protein, middle domain CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 PIRSF PIRSF006809 6 412 1.3E-143 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 Gene3D G3DSA:3.40.50.300 175 237 1.5E-11 T 28-03-2018 CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 SUPERFAMILY SSF52540 206 376 9.11E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 Pfam PF01926 50S ribosome-binding GTPase 207 326 1.1E-17 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 16 361 3.9E-138 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CWR44_RS08940 ed716e180309e4ef69fa6a6fd0119545 412 Pfam PF13167 GTP-binding GTPase N-terminal 33 120 4.4E-29 T 28-03-2018 IPR025121 GTPase HflX, N-terminal CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 2.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 2.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 2.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 2.4E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 8.0E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 8.0E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 8.0E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 Pfam PF00106 short chain dehydrogenase 4 180 2.9E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 SUPERFAMILY SSF51735 3 246 1.27E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS06820 4a506ff60fe1e07ef9498b70be698089 272 Gene3D G3DSA:3.40.50.720 2 269 6.9E-63 T 28-03-2018 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 SMART SM00155 407 434 3.2E-8 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 SMART SM00155 229 256 1.3E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 Hamap MF_01916 Cardiolipin synthase. 21 494 43.987 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 Gene3D G3DSA:3.30.870.10 97 295 6.9E-35 T 28-03-2018 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 Pfam PF13091 PLD-like domain 147 260 2.5E-14 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 Pfam PF13091 PLD-like domain 335 461 6.7E-31 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 Gene3D G3DSA:3.30.870.10 324 488 9.5E-36 T 28-03-2018 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 SUPERFAMILY SSF56024 89 327 2.83E-55 T 28-03-2018 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 15 494 2.8E-230 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 SUPERFAMILY SSF56024 281 481 4.26E-55 T 28-03-2018 CWR44_RS00070 6c800c153d854009099fdbc2ddd8e6eb 494 Pfam PF13396 Phospholipase_D-nuclease N-terminal 25 68 4.8E-11 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CWR44_RS12295 c23c8352cf489301918d7ad54e0ccf4e 403 Pfam PF03631 Virulence factor BrkB 77 328 9.5E-69 T 28-03-2018 IPR017039 Virulence factor BrkB CWR44_RS12295 c23c8352cf489301918d7ad54e0ccf4e 403 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 66 327 8.8E-52 T 28-03-2018 IPR017039 Virulence factor BrkB CWR44_RS12295 c23c8352cf489301918d7ad54e0ccf4e 403 PIRSF PIRSF035875 49 349 1.8E-105 T 28-03-2018 IPR017039 Virulence factor BrkB CWR44_RS05205 d410a0dd6f29849a01affcd842fc1e0e 105 Pfam PF02575 YbaB/EbfC DNA-binding family 11 101 1.8E-32 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR44_RS05205 d410a0dd6f29849a01affcd842fc1e0e 105 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 4 105 9.3E-30 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR44_RS05205 d410a0dd6f29849a01affcd842fc1e0e 105 PIRSF PIRSF004555 3 105 3.3E-38 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR44_RS05205 d410a0dd6f29849a01affcd842fc1e0e 105 SUPERFAMILY SSF82607 11 105 4.19E-33 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR44_RS05205 d410a0dd6f29849a01affcd842fc1e0e 105 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 99 23.104 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR44_RS05205 d410a0dd6f29849a01affcd842fc1e0e 105 Gene3D G3DSA:3.30.1310.10 1 105 5.2E-36 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CWR44_RS08205 1cb9d859e5d21680c844be97eec6ea87 104 Pfam PF00085 Thioredoxin 3 103 6.5E-33 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWR44_RS08205 1cb9d859e5d21680c844be97eec6ea87 104 PRINTS PR00421 Thioredoxin family signature 28 37 2.5E-8 T 28-03-2018 CWR44_RS08205 1cb9d859e5d21680c844be97eec6ea87 104 PRINTS PR00421 Thioredoxin family signature 20 28 2.5E-8 T 28-03-2018 CWR44_RS08205 1cb9d859e5d21680c844be97eec6ea87 104 PRINTS PR00421 Thioredoxin family signature 68 79 2.5E-8 T 28-03-2018 CWR44_RS08205 1cb9d859e5d21680c844be97eec6ea87 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CWR44_RS08205 1cb9d859e5d21680c844be97eec6ea87 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 103 4.1E-39 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CWR44_RS08205 1cb9d859e5d21680c844be97eec6ea87 104 SUPERFAMILY SSF52833 2 104 1.19E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS08205 1cb9d859e5d21680c844be97eec6ea87 104 PIRSF PIRSF000077 1 104 4.5E-44 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CWR44_RS08205 1cb9d859e5d21680c844be97eec6ea87 104 Gene3D G3DSA:3.40.30.10 1 104 2.0E-36 T 28-03-2018 CWR44_RS03070 cbc731ab0eb0960dc1e0aa79664b0ff4 306 SUPERFAMILY SSF103481 196 302 4.45E-12 T 28-03-2018 CWR44_RS03070 cbc731ab0eb0960dc1e0aa79664b0ff4 306 SUPERFAMILY SSF103481 46 153 5.89E-10 T 28-03-2018 CWR44_RS03070 cbc731ab0eb0960dc1e0aa79664b0ff4 306 Pfam PF00892 EamA-like transporter family 162 298 4.0E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR44_RS03070 cbc731ab0eb0960dc1e0aa79664b0ff4 306 Pfam PF00892 EamA-like transporter family 12 151 1.0E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR44_RS09955 a0ce98328f28e8e384481d4d649ea811 534 Pfam PF12848 ABC transporter 224 309 6.7E-21 T 28-03-2018 IPR032781 ABC-transporter extension domain CWR44_RS09955 a0ce98328f28e8e384481d4d649ea811 534 SUPERFAMILY SSF52540 295 527 1.94E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS09955 a0ce98328f28e8e384481d4d649ea811 534 SUPERFAMILY SSF52540 125 252 1.73E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS09955 a0ce98328f28e8e384481d4d649ea811 534 SUPERFAMILY SSF52540 2 92 1.73E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS09955 a0ce98328f28e8e384481d4d649ea811 534 Gene3D G3DSA:3.40.50.300 1 283 3.3E-55 T 28-03-2018 CWR44_RS09955 a0ce98328f28e8e384481d4d649ea811 534 Gene3D G3DSA:3.40.50.300 284 534 6.3E-40 T 28-03-2018 CWR44_RS09955 a0ce98328f28e8e384481d4d649ea811 534 Pfam PF00005 ABC transporter 335 469 5.3E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS09955 a0ce98328f28e8e384481d4d649ea811 534 Pfam PF00005 ABC transporter 18 184 1.5E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS09955 a0ce98328f28e8e384481d4d649ea811 534 SMART SM00382 26 238 4.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS09955 a0ce98328f28e8e384481d4d649ea811 534 SMART SM00382 344 514 1.8E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS05750 cbd468c4c5a468843ace2313f5e25036 220 Gene3D G3DSA:3.40.50.300 7 212 3.9E-45 T 28-03-2018 CWR44_RS05750 cbd468c4c5a468843ace2313f5e25036 220 SUPERFAMILY SSF52540 9 211 2.34E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05750 cbd468c4c5a468843ace2313f5e25036 220 PIRSF PIRSF000705 1 218 1.2E-64 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CWR44_RS05750 cbd468c4c5a468843ace2313f5e25036 220 Pfam PF01712 Deoxynucleoside kinase 12 211 2.6E-63 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 Pfam PF00258 Flavodoxin 87 218 5.3E-31 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 SUPERFAMILY SSF52343 467 622 7.86E-49 T 28-03-2018 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 Pfam PF00175 Oxidoreductase NAD-binding domain 480 586 1.7E-16 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PIRSF PIRSF000207 1 622 1.6E-273 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 SUPERFAMILY SSF63380 250 468 5.88E-61 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 Pfam PF00667 FAD binding domain 250 445 2.1E-29 T 28-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 548 564 4.7E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 290 300 4.7E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 409 416 4.7E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 504 513 4.7E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 571 579 4.7E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 442 451 4.7E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 479 498 4.7E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 517 528 4.7E-24 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 Gene3D G3DSA:3.40.50.360 42 242 6.5E-42 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 Gene3D G3DSA:2.40.30.10 243 462 4.0E-47 T 28-03-2018 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00369 Flavodoxin signature 86 99 2.5E-15 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00369 Flavodoxin signature 166 176 2.5E-15 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00369 Flavodoxin signature 190 209 2.5E-15 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 PRINTS PR00369 Flavodoxin signature 134 145 2.5E-15 T 28-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 6 622 4.0E-238 T 28-03-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 Gene3D G3DSA:3.40.50.80 476 622 3.6E-35 T 28-03-2018 CWR44_RS02625 d847083196f80354759379ad6bbe0cc5 622 SUPERFAMILY SSF52218 83 227 1.6E-47 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS07705 1cd761565dcb95a8f6c9185b0f1f4345 455 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 103 447 4.0E-110 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CWR44_RS07705 1cd761565dcb95a8f6c9185b0f1f4345 455 Gene3D G3DSA:3.60.120.10 2 450 1.4E-88 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CWR44_RS07705 1cd761565dcb95a8f6c9185b0f1f4345 455 SUPERFAMILY SSF56322 37 448 1.44E-90 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CWR44_RS07705 1cd761565dcb95a8f6c9185b0f1f4345 455 Pfam PF00425 chorismate binding enzyme 191 439 9.8E-65 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CWR44_RS01900 86782a7df8370c9748cdf7871dfa0f8f 512 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 3 508 3.6E-284 T 28-03-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CWR44_RS01900 86782a7df8370c9748cdf7871dfa0f8f 512 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 364 384 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR44_RS01900 86782a7df8370c9748cdf7871dfa0f8f 512 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 247 6.5E-73 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CWR44_RS01900 86782a7df8370c9748cdf7871dfa0f8f 512 SUPERFAMILY SSF53067 1 247 1.97E-69 T 28-03-2018 CWR44_RS01900 86782a7df8370c9748cdf7871dfa0f8f 512 Gene3D G3DSA:3.30.420.40 249 512 7.4E-61 T 28-03-2018 CWR44_RS01900 86782a7df8370c9748cdf7871dfa0f8f 512 PIRSF PIRSF000538 1 505 1.2E-141 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR44_RS01900 86782a7df8370c9748cdf7871dfa0f8f 512 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 257 452 1.5E-33 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CWR44_RS01900 86782a7df8370c9748cdf7871dfa0f8f 512 SUPERFAMILY SSF53067 252 498 5.98E-65 T 28-03-2018 CWR44_RS01900 86782a7df8370c9748cdf7871dfa0f8f 512 Gene3D G3DSA:3.30.420.40 1 248 9.6E-67 T 28-03-2018 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 3.0E-33 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 6.1E-31 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 SUPERFAMILY SSF55681 118 418 4.07E-100 T 28-03-2018 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 8.0E-172 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 4.8E-34 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 4.8E-34 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 4.8E-34 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 4.8E-34 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 4.8E-34 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 Gene3D G3DSA:1.10.287.40 2 105 3.5E-28 T 28-03-2018 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 PIRSF PIRSF001529 1 426 1.3E-196 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 Gene3D G3DSA:3.30.930.10 106 427 5.4E-95 T 28-03-2018 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 42.673 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CWR44_RS04410 853255468276f2bbcc92ec4ec3591612 428 SUPERFAMILY SSF46589 1 113 9.42E-29 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWR44_RS08715 b414dd4ffa18dcb1ce7e887e006a8d2d 260 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 218 244 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CWR44_RS08715 b414dd4ffa18dcb1ce7e887e006a8d2d 260 Pfam PF01148 Cytidylyltransferase family 2 257 5.1E-73 T 28-03-2018 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 SUPERFAMILY SSF51735 3 179 4.26E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 3.6E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 3.6E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 3.6E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 3.6E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 3.6E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 3.6E-40 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 Gene3D G3DSA:3.40.50.720 1 180 8.3E-39 T 28-03-2018 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 36.826 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 PIRSF PIRSF000114 1 332 1.6E-113 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 160 1.0E-51 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 Gene3D G3DSA:1.10.1040.10 181 331 3.9E-57 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 321 8.0E-56 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CWR44_RS10330 f9c95e81166c0fa53e06a9e0e3c39a07 332 SUPERFAMILY SSF48179 180 332 7.48E-59 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR44_RS05970 934334e34e3c81622b5cb592c02136a6 146 Pfam PF02082 Transcriptional regulator 3 78 6.9E-17 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CWR44_RS05970 934334e34e3c81622b5cb592c02136a6 146 Gene3D G3DSA:1.10.10.10 1 144 4.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS05970 934334e34e3c81622b5cb592c02136a6 146 SUPERFAMILY SSF46785 2 135 2.04E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS13120 ab78564cfc8817d417b5d3095ef65d27 202 Pfam PF00239 Resolvase, N terminal domain 2 145 4.0E-33 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS13120 ab78564cfc8817d417b5d3095ef65d27 202 SUPERFAMILY SSF53041 1 145 3.79E-36 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS13120 ab78564cfc8817d417b5d3095ef65d27 202 Gene3D G3DSA:1.20.5.40 115 143 5.8E-9 T 28-03-2018 CWR44_RS13120 ab78564cfc8817d417b5d3095ef65d27 202 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CWR44_RS13120 ab78564cfc8817d417b5d3095ef65d27 202 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CWR44_RS13120 ab78564cfc8817d417b5d3095ef65d27 202 Gene3D G3DSA:3.40.50.1390 1 114 1.2E-29 T 28-03-2018 CWR44_RS13120 ab78564cfc8817d417b5d3095ef65d27 202 Gene3D G3DSA:1.10.10.60 146 202 2.7E-15 T 28-03-2018 CWR44_RS13120 ab78564cfc8817d417b5d3095ef65d27 202 Pfam PF02796 Helix-turn-helix domain of resolvase 147 198 4.5E-20 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS13120 ab78564cfc8817d417b5d3095ef65d27 202 SMART SM00857 2 145 4.9E-43 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 ProSitePatterns PS00211 ABC transporters family signature. 641 655 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 Gene3D G3DSA:1.10.8.280 145 256 2.0E-19 T 28-03-2018 CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 Gene3D G3DSA:1.20.1580.10 92 124 1.4E-6 T 28-03-2018 CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 Gene3D G3DSA:3.40.50.300 274 467 2.4E-25 T 28-03-2018 CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 Pfam PF00005 ABC transporter 465 670 1.6E-11 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 SUPERFAMILY SSF52540 462 716 2.07E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 SUPERFAMILY SSF52540 277 409 5.23E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 SUPERFAMILY SSF52540 1 151 5.23E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 Gene3D G3DSA:3.40.50.300 15 53 0.029 T 28-03-2018 CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 SMART SM00382 474 716 1.3 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 SMART SM00382 23 411 0.52 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03105 ad2aa20dd0f5e6ddaf1af3473986f719 752 Gene3D G3DSA:3.40.50.300 468 751 9.7E-46 T 28-03-2018 CWR44_RS01070 995a4a96b2256e345ca240cfb436a7ac 233 SUPERFAMILY SSF46785 3 63 1.01E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01070 995a4a96b2256e345ca240cfb436a7ac 233 Gene3D G3DSA:1.10.10.10 1 66 5.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01070 995a4a96b2256e345ca240cfb436a7ac 233 SMART SM00420 7 63 8.3E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR44_RS01070 995a4a96b2256e345ca240cfb436a7ac 233 Pfam PF08279 HTH domain 7 62 2.4E-16 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CWR44_RS03985 4a77782424b9d133723309638af5804c 133 SUPERFAMILY SSF52788 3 129 8.24E-46 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR44_RS03985 4a77782424b9d133723309638af5804c 133 SMART SM00226 4 131 6.9E-61 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR44_RS03985 4a77782424b9d133723309638af5804c 133 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 128 1.2E-25 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR44_RS03985 4a77782424b9d133723309638af5804c 133 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 6 128 4.9E-66 T 28-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 CWR44_RS03985 4a77782424b9d133723309638af5804c 133 Gene3D G3DSA:3.40.50.2300 1 131 6.7E-43 T 28-03-2018 CWR44_RS03985 4a77782424b9d133723309638af5804c 133 Hamap MF_01624 Protein ArsC [arsC]. 1 131 47.774 T 28-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 SUPERFAMILY SSF54980 401 516 1.25E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 Gene3D G3DSA:3.40.50.300 71 203 3.4E-31 T 28-03-2018 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 601 1.7E-286 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 Pfam PF03144 Elongation factor Tu domain 2 222 292 5.4E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 SUPERFAMILY SSF52540 4 210 3.63E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 SMART SM00838 398 483 3.0E-5 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 Pfam PF00009 Elongation factor Tu GTP binding domain 7 198 5.8E-57 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 141 6.4E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 Gene3D G3DSA:3.40.50.300 1 70 3.8E-10 T 28-03-2018 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 SUPERFAMILY SSF50447 155 302 2.02E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 Gene3D G3DSA:3.30.70.240 404 495 3.8E-17 T 28-03-2018 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 Gene3D G3DSA:2.40.30.10 205 305 3.5E-20 T 28-03-2018 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 SUPERFAMILY SSF54980 305 390 1.08E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 Gene3D G3DSA:2.40.50.250 496 576 5.9E-38 T 28-03-2018 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 Gene3D G3DSA:3.30.70.870 306 403 2.1E-32 T 28-03-2018 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 Pfam PF00679 Elongation factor G C-terminus 399 477 2.2E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.3E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.3E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.3E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.3E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS08065 6861784c342cd274f07ce4280974c29e 614 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.3E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 510 1.1E-17 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 177 1.1E-33 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 SUPERFAMILY SSF52518 4 177 6.58E-40 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 Gene3D G3DSA:3.40.50.970 1 193 1.5E-43 T 28-03-2018 CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 SUPERFAMILY SSF52518 352 532 5.34E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 Gene3D G3DSA:3.40.50.970 343 539 4.1E-33 T 28-03-2018 CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 PIRSF PIRSF036565 1 546 5.2E-201 T 28-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 SUPERFAMILY SSF52467 165 326 1.22E-30 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 413 432 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 319 6.5E-23 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CWR44_RS02780 156fe90a08e304487a036e48451dc243 546 Gene3D G3DSA:3.40.50.1220 194 329 3.9E-22 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 SUPERFAMILY SSF47323 645 914 8.6E-79 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 Gene3D G3DSA:3.90.740.10 218 490 8.5E-94 T 28-03-2018 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 SUPERFAMILY SSF50677 201 394 7.85E-61 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 Gene3D G3DSA:3.40.50.620 28 217 1.9E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 Pfam PF06827 Zinc finger found in FPG and IleRS 882 911 5.6E-11 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 26 634 3.0E-233 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 829 2.3E-296 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 913 20.778 T 28-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 Gene3D G3DSA:3.30.2320.20 793 880 2.4E-24 T 28-03-2018 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 Gene3D G3DSA:1.10.730.10 571 792 8.9E-49 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 SUPERFAMILY SSF52374 1 200 3.6E-153 T 28-03-2018 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 SUPERFAMILY SSF52374 394 641 3.6E-153 T 28-03-2018 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 392 407 2.7E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 554 563 2.7E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 2.7E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 2.7E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 520 533 2.7E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CWR44_RS08370 a38a27c4cc36a91c0e70095b080005b8 916 Pfam PF08264 Anticodon-binding domain of tRNA 678 831 1.5E-28 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 7 147 2.1E-46 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 Gene3D G3DSA:3.40.50.1370 1 146 1.4E-53 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 328 5.2E-55 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 6 331 81.42 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 SUPERFAMILY SSF53671 2 331 3.8E-100 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 7 330 5.3E-123 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 Gene3D G3DSA:3.40.50.1370 147 317 1.0E-51 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 52 59 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 295 318 2.6E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 2.6E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 275 2.6E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 2.6E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 50 64 6.2E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 83 96 6.2E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 309 320 6.2E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 6.2E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS03345 bea5ae2dcae17f4354624b179373f70d 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 123 137 6.2E-30 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 Gene3D G3DSA:3.30.310.50 446 543 9.0E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 Gene3D G3DSA:3.40.120.10 8 201 2.6E-50 T 28-03-2018 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 310 426 2.2E-17 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 Gene3D G3DSA:3.40.120.10 322 434 6.9E-29 T 28-03-2018 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 198 298 2.0E-23 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 SUPERFAMILY SSF53738 289 434 1.49E-23 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 SUPERFAMILY SSF53738 196 300 9.81E-21 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 128 142 1.3E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 214 233 1.3E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 281 296 1.3E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 129 138 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 35 168 2.0E-41 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 SUPERFAMILY SSF55957 447 537 1.7E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 SUPERFAMILY SSF53738 24 220 2.0E-43 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 479 525 5.8E-7 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03130 14404d5b72b79e056b4bb4dbbfd46fc5 548 Gene3D G3DSA:3.40.120.10 202 321 2.3E-26 T 28-03-2018 CWR44_RS12720 00013cfb233c3250470387f8978f8e16 562 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 464 475 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWR44_RS12720 00013cfb233c3250470387f8978f8e16 562 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 556 4.3E-236 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWR44_RS12720 00013cfb233c3250470387f8978f8e16 562 SUPERFAMILY SSF143975 1 375 2.75E-133 T 28-03-2018 CWR44_RS12720 00013cfb233c3250470387f8978f8e16 562 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 556 45.324 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWR44_RS12720 00013cfb233c3250470387f8978f8e16 562 Gene3D G3DSA:3.40.50.2300 36 260 1.6E-5 T 28-03-2018 CWR44_RS12720 00013cfb233c3250470387f8978f8e16 562 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 121 131 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWR44_RS12720 00013cfb233c3250470387f8978f8e16 562 Pfam PF00920 Dehydratase family 33 552 1.6E-219 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CWR44_RS12720 00013cfb233c3250470387f8978f8e16 562 SUPERFAMILY SSF52016 376 556 1.1E-58 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR44_RS10560 c8c041c82eb4e67fc6d8f9288a9c67af 161 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 122 135 1.2E-15 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWR44_RS10560 c8c041c82eb4e67fc6d8f9288a9c67af 161 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 107 121 1.2E-15 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWR44_RS10560 c8c041c82eb4e67fc6d8f9288a9c67af 161 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 90 103 1.2E-15 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWR44_RS10560 c8c041c82eb4e67fc6d8f9288a9c67af 161 Pfam PF00364 Biotin-requiring enzyme 87 159 4.0E-23 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CWR44_RS10560 c8c041c82eb4e67fc6d8f9288a9c67af 161 Gene3D G3DSA:2.40.50.100 6 161 2.1E-17 T 28-03-2018 CWR44_RS10560 c8c041c82eb4e67fc6d8f9288a9c67af 161 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 161 1.1E-51 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWR44_RS10560 c8c041c82eb4e67fc6d8f9288a9c67af 161 SUPERFAMILY SSF51230 85 160 2.62E-22 T 28-03-2018 IPR011053 Single hybrid motif CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Gene3D G3DSA:3.10.600.10 463 533 5.2E-18 T 28-03-2018 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 SUPERFAMILY SSF56059 86 330 3.18E-67 T 28-03-2018 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Gene3D G3DSA:1.10.10.60 945 991 4.2E-19 T 28-03-2018 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 SUPERFAMILY SSF51569 525 837 1.5E-80 T 28-03-2018 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Gene3D G3DSA:3.10.600.10 992 1062 2.3E-18 T 28-03-2018 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 PIRSF PIRSF001594 1 1147 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 SUPERFAMILY SSF89000 834 1011 7.45E-56 T 28-03-2018 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 SUPERFAMILY SSF52440 3 115 1.37E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 112 3.6E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 SUPERFAMILY SSF51246 340 457 5.23E-38 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 SUPERFAMILY SSF51230 1066 1146 9.68E-21 T 28-03-2018 IPR011053 Single hybrid motif CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Gene3D G3DSA:3.40.50.20 3 132 1.3E-50 T 28-03-2018 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Gene3D G3DSA:3.30.1490.20 133 205 7.9E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Gene3D G3DSA:3.20.20.70 534 821 4.6E-65 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Gene3D G3DSA:3.30.470.20 207 453 1.4E-91 T 28-03-2018 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Pfam PF00682 HMGL-like 535 805 1.7E-25 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 SMART SM00878 344 451 1.0E-51 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Pfam PF00364 Biotin-requiring enzyme 1081 1145 1.1E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Gene3D G3DSA:2.40.50.100 1075 1147 2.5E-18 T 28-03-2018 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 118 323 3.0E-75 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Pfam PF02785 Biotin carboxylase C-terminal domain 344 452 5.3E-33 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 6 1146 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CWR44_RS08090 b2c37af573a69a38cbc5cfcb6a01b580 1149 Pfam PF02436 Conserved carboxylase domain 829 1029 7.9E-74 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CWR44_RS12420 770c6ec8c522aea7922d63db45093b33 100 Gene3D G3DSA:1.10.1270.10 1 100 5.1E-34 T 28-03-2018 CWR44_RS12420 770c6ec8c522aea7922d63db45093b33 100 Pfam PF01371 Trp repressor protein 9 94 4.6E-34 T 28-03-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 CWR44_RS12420 770c6ec8c522aea7922d63db45093b33 100 SUPERFAMILY SSF48295 3 95 5.02E-31 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CWR44_RS12420 770c6ec8c522aea7922d63db45093b33 100 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 1.1E-48 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD CWR44_RS12420 770c6ec8c522aea7922d63db45093b33 100 PIRSF PIRSF012508 1 100 1.8E-46 T 28-03-2018 IPR013368 TrpR homologue YerC/YecD CWR44_RS01505 6ddd3bf74ab3dd4b3a939dffd5d6d5b3 517 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 359 439 1.5E-28 T 28-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 CWR44_RS01505 6ddd3bf74ab3dd4b3a939dffd5d6d5b3 517 Gene3D G3DSA:3.30.70.20 237 361 5.8E-28 T 28-03-2018 CWR44_RS01505 6ddd3bf74ab3dd4b3a939dffd5d6d5b3 517 Gene3D G3DSA:3.30.70.20 199 236 3.8E-18 T 28-03-2018 CWR44_RS01505 6ddd3bf74ab3dd4b3a939dffd5d6d5b3 517 Gene3D G3DSA:1.10.3650.10 362 437 2.8E-28 T 28-03-2018 CWR44_RS01505 6ddd3bf74ab3dd4b3a939dffd5d6d5b3 517 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 491 1.8E-252 T 28-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CWR44_RS01505 6ddd3bf74ab3dd4b3a939dffd5d6d5b3 517 SUPERFAMILY SSF54862 2 487 3.35E-163 T 28-03-2018 CWR44_RS01505 6ddd3bf74ab3dd4b3a939dffd5d6d5b3 517 Gene3D G3DSA:3.30.70.20 5 198 5.8E-29 T 28-03-2018 CWR44_RS01505 6ddd3bf74ab3dd4b3a939dffd5d6d5b3 517 Pfam PF13247 4Fe-4S dicluster domain 176 272 3.2E-36 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR44_RS00680 5c3457ccbe3d4cb4b361314b0e18e55a 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 1.0E-8 T 28-03-2018 CWR44_RS00680 5c3457ccbe3d4cb4b361314b0e18e55a 37 SUPERFAMILY SSF57840 1 37 5.76E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00680 5c3457ccbe3d4cb4b361314b0e18e55a 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00680 5c3457ccbe3d4cb4b361314b0e18e55a 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.56 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00680 5c3457ccbe3d4cb4b361314b0e18e55a 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.7E-24 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00680 5c3457ccbe3d4cb4b361314b0e18e55a 37 Pfam PF00444 Ribosomal protein L36 1 37 1.5E-19 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS02465 22ebc9c86b1e322a721e69582300de28 296 SUPERFAMILY SSF51569 4 294 9.42E-93 T 28-03-2018 CWR44_RS02465 22ebc9c86b1e322a721e69582300de28 296 Hamap MF_00729 Fructose-bisphosphate aldolase class 1 [fda]. 2 293 52.367 T 28-03-2018 IPR023014 Fructose-bisphosphate aldolase class I, Gram positive bacteria-type GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CWR44_RS02465 22ebc9c86b1e322a721e69582300de28 296 Pfam PF00274 Fructose-bisphosphate aldolase class-I 9 211 2.8E-13 T 28-03-2018 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS02465 22ebc9c86b1e322a721e69582300de28 296 Gene3D G3DSA:3.20.20.70 1 293 5.5E-70 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 292 6.3E-93 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 288 1.1E-19 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 44 51 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 44 63 2.9E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 245 254 2.9E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 280 2.9E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 2.9E-23 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 140 4.7E-41 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 SUPERFAMILY SSF53671 1 294 7.07E-88 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 Gene3D G3DSA:3.40.50.1370 1 140 5.9E-47 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 Gene3D G3DSA:3.40.50.1370 141 295 3.9E-45 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 2.6E-33 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 249 254 2.6E-33 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 206 215 2.6E-33 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 34 56 2.6E-33 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 273 287 2.6E-33 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 72 81 2.6E-33 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08410 894cf142abf94f108b63ea5714e61ce0 297 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 294 38.741 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 450 6.3E-147 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 Gene3D G3DSA:3.30.390.30 333 450 1.3E-33 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 SUPERFAMILY SSF55424 330 450 3.44E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 SUPERFAMILY SSF51905 5 360 7.61E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 Gene3D G3DSA:3.50.50.60 228 332 1.9E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 Gene3D G3DSA:3.50.50.60 111 227 2.4E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 332 439 1.0E-27 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 298 1.0E-36 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 1.0E-36 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 1.0E-36 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 1.0E-36 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.0E-36 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PIRSF PIRSF000350 1 448 1.9E-84 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 311 1.9E-67 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 Gene3D G3DSA:1.10.287.990 37 104 4.8E-22 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 6.5E-64 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 392 407 6.5E-64 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.5E-64 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 6.5E-64 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 327 348 6.5E-64 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 6.5E-64 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 291 298 6.5E-64 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 6.5E-64 T 28-03-2018 CWR44_RS03480 f4bc4fdddffa1104cf05f413d972dc8d 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 414 434 6.5E-64 T 28-03-2018 CWR44_RS05505 fd99f107207f84ced3145ff3cd76cc2b 453 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 3.7E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS05505 fd99f107207f84ced3145ff3cd76cc2b 453 Pfam PF00155 Aminotransferase class I and II 132 372 1.5E-15 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR44_RS05505 fd99f107207f84ced3145ff3cd76cc2b 453 Gene3D G3DSA:1.10.10.10 1 71 1.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS05505 fd99f107207f84ced3145ff3cd76cc2b 453 SUPERFAMILY SSF46785 2 73 1.59E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS05505 fd99f107207f84ced3145ff3cd76cc2b 453 SUPERFAMILY SSF53383 63 445 8.55E-60 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS05505 fd99f107207f84ced3145ff3cd76cc2b 453 SMART SM00345 10 69 6.0E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS05505 fd99f107207f84ced3145ff3cd76cc2b 453 Gene3D G3DSA:3.90.1150.10 344 446 2.4E-8 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS05505 fd99f107207f84ced3145ff3cd76cc2b 453 Gene3D G3DSA:3.40.640.10 140 343 1.1E-24 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS08110 89f0f1aff417eb9034954f4c35b65826 352 Pfam PF14504 CAP-associated N-terminal 67 205 1.2E-39 T 28-03-2018 IPR029410 CAP-associated domain CWR44_RS08110 89f0f1aff417eb9034954f4c35b65826 352 Pfam PF00188 Cysteine-rich secretory protein family 243 342 5.8E-8 T 28-03-2018 IPR014044 CAP domain CWR44_RS08110 89f0f1aff417eb9034954f4c35b65826 352 SUPERFAMILY SSF55797 234 337 4.45E-8 T 28-03-2018 IPR014044 CAP domain CWR44_RS11595 68d43a3d3d94f9c080f3460f4b91c439 357 SUPERFAMILY SSF53187 172 345 1.77E-66 T 28-03-2018 CWR44_RS11595 68d43a3d3d94f9c080f3460f4b91c439 357 SUPERFAMILY SSF53187 6 83 1.77E-66 T 28-03-2018 CWR44_RS11595 68d43a3d3d94f9c080f3460f4b91c439 357 Gene3D G3DSA:2.40.30.40 72 163 8.3E-25 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CWR44_RS11595 68d43a3d3d94f9c080f3460f4b91c439 357 SUPERFAMILY SSF101821 73 180 8.7E-27 T 28-03-2018 CWR44_RS11595 68d43a3d3d94f9c080f3460f4b91c439 357 PIRSF PIRSF001123 3 356 2.1E-132 T 28-03-2018 IPR008007 Peptidase M42 CWR44_RS11595 68d43a3d3d94f9c080f3460f4b91c439 357 Pfam PF05343 M42 glutamyl aminopeptidase 47 337 3.6E-97 T 28-03-2018 IPR008007 Peptidase M42 CWR44_RS11595 68d43a3d3d94f9c080f3460f4b91c439 357 Gene3D G3DSA:3.40.630.10 164 354 1.4E-39 T 28-03-2018 CWR44_RS00130 1228fa0fc04de20d463c372ea06793a4 421 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 419 44.74 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00130 1228fa0fc04de20d463c372ea06793a4 421 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 409 5.7E-111 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR44_RS00130 1228fa0fc04de20d463c372ea06793a4 421 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 418 1.7E-176 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00130 1228fa0fc04de20d463c372ea06793a4 421 Gene3D G3DSA:3.65.10.10 21 223 2.7E-46 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR44_RS00130 1228fa0fc04de20d463c372ea06793a4 421 Gene3D G3DSA:3.65.10.10 224 421 2.2E-51 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR44_RS00130 1228fa0fc04de20d463c372ea06793a4 421 SUPERFAMILY SSF55205 1 420 8.63E-140 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CWR44_RS00755 d6d987866c6974426d2d4ac9991049aa 69 Gene3D G3DSA:1.10.287.310 1 65 1.4E-24 T 28-03-2018 CWR44_RS00755 d6d987866c6974426d2d4ac9991049aa 69 SUPERFAMILY SSF46561 1 63 7.85E-23 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00755 d6d987866c6974426d2d4ac9991049aa 69 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 2.6E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00755 d6d987866c6974426d2d4ac9991049aa 69 Pfam PF00831 Ribosomal L29 protein 4 60 2.8E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00755 d6d987866c6974426d2d4ac9991049aa 69 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.564 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS01675 a94f9cdd151c315cfed83a76f2fa3402 608 Pfam PF13520 Amino acid permease 26 446 8.6E-36 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS01150 5de072f0f5d95afd45871c5f716b7ec6 203 Pfam PF01613 Flavin reductase like domain 23 165 9.6E-20 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CWR44_RS01150 5de072f0f5d95afd45871c5f716b7ec6 203 SMART SM00903 20 170 2.3E-15 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CWR44_RS01150 5de072f0f5d95afd45871c5f716b7ec6 203 SUPERFAMILY SSF50475 3 197 1.57E-40 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR44_RS01150 5de072f0f5d95afd45871c5f716b7ec6 203 Gene3D G3DSA:2.30.110.10 2 199 9.9E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR44_RS01745 a3b8f2852bd223f94fe230be4a1cc0de 211 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 202 2.6E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS01745 a3b8f2852bd223f94fe230be4a1cc0de 211 SUPERFAMILY SSF161098 11 195 8.63E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS01745 a3b8f2852bd223f94fe230be4a1cc0de 211 Gene3D G3DSA:1.10.3720.10 1 207 1.3E-28 T 28-03-2018 CWR44_RS01845 fd07d244f2a69e5c9c742f51a486cb9d 513 Gene3D G3DSA:3.30.420.150 125 309 1.6E-42 T 28-03-2018 CWR44_RS01845 fd07d244f2a69e5c9c742f51a486cb9d 513 SUPERFAMILY SSF53067 4 125 5.18E-29 T 28-03-2018 CWR44_RS01845 fd07d244f2a69e5c9c742f51a486cb9d 513 SUPERFAMILY SSF53067 129 306 7.77E-42 T 28-03-2018 CWR44_RS01845 fd07d244f2a69e5c9c742f51a486cb9d 513 Pfam PF02541 Ppx/GppA phosphatase family 26 303 5.6E-54 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CWR44_RS01845 fd07d244f2a69e5c9c742f51a486cb9d 513 SUPERFAMILY SSF109604 315 511 7.22E-26 T 28-03-2018 CWR44_RS01845 fd07d244f2a69e5c9c742f51a486cb9d 513 Gene3D G3DSA:3.30.420.40 1 124 3.6E-33 T 28-03-2018 CWR44_RS01845 fd07d244f2a69e5c9c742f51a486cb9d 513 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 4 303 8.7E-101 T 28-03-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 CWR44_RS08670 8a41bb7aee3d8de94b513b7e275ac81d 297 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 7 294 8.7E-105 T 28-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CWR44_RS08670 8a41bb7aee3d8de94b513b7e275ac81d 297 Gene3D G3DSA:1.10.150.130 1 107 7.2E-22 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR44_RS08670 8a41bb7aee3d8de94b513b7e275ac81d 297 SUPERFAMILY SSF47823 7 96 1.55E-18 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CWR44_RS08670 8a41bb7aee3d8de94b513b7e275ac81d 297 Pfam PF00589 Phage integrase family 109 278 1.9E-45 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS08670 8a41bb7aee3d8de94b513b7e275ac81d 297 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 86 4.9E-17 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWR44_RS08670 8a41bb7aee3d8de94b513b7e275ac81d 297 Gene3D G3DSA:1.10.443.10 108 286 1.1E-46 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS08670 8a41bb7aee3d8de94b513b7e275ac81d 297 SUPERFAMILY SSF56349 104 290 1.97E-52 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR44_RS08670 8a41bb7aee3d8de94b513b7e275ac81d 297 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 292 53.36 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CWR44_RS08470 e338f8ed68a6197cd53b318f61b415eb 802 Gene3D G3DSA:3.40.50.300 463 694 2.1E-23 T 28-03-2018 CWR44_RS08470 e338f8ed68a6197cd53b318f61b415eb 802 SUPERFAMILY SSF52540 529 705 3.26E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08470 e338f8ed68a6197cd53b318f61b415eb 802 SMART SM00490 563 660 7.3E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS08470 e338f8ed68a6197cd53b318f61b415eb 802 TIGRFAM TIGR00595 priA: primosomal protein N' 289 798 4.4E-214 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CWR44_RS08470 e338f8ed68a6197cd53b318f61b415eb 802 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 801 25.296 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CWR44_RS08470 e338f8ed68a6197cd53b318f61b415eb 802 SUPERFAMILY SSF52540 187 448 4.18E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08470 e338f8ed68a6197cd53b318f61b415eb 802 SMART SM00487 261 460 7.8E-21 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS08470 e338f8ed68a6197cd53b318f61b415eb 802 Pfam PF00271 Helicase conserved C-terminal domain 563 659 3.5E-8 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS08470 e338f8ed68a6197cd53b318f61b415eb 802 Pfam PF04851 Type III restriction enzyme, res subunit 264 428 2.7E-18 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWR44_RS08470 e338f8ed68a6197cd53b318f61b415eb 802 Gene3D G3DSA:3.40.50.300 262 430 5.0E-26 T 28-03-2018 CWR44_RS07565 1d0945839069ffba270c610fbbfdb020 614 Gene3D G3DSA:3.40.50.720 395 515 7.2E-7 T 28-03-2018 CWR44_RS07565 1d0945839069ffba270c610fbbfdb020 614 Pfam PF00999 Sodium/hydrogen exchanger family 7 388 2.8E-73 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CWR44_RS07565 1d0945839069ffba270c610fbbfdb020 614 Gene3D G3DSA:3.30.70.1450 537 611 2.2E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR44_RS07565 1d0945839069ffba270c610fbbfdb020 614 Pfam PF02254 TrkA-N domain 442 513 5.6E-5 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CWR44_RS07565 1d0945839069ffba270c610fbbfdb020 614 Gene3D G3DSA:1.20.91.10 240 322 3.4E-17 T 28-03-2018 CWR44_RS07565 1d0945839069ffba270c610fbbfdb020 614 SUPERFAMILY SSF116726 538 611 4.97E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR44_RS07565 1d0945839069ffba270c610fbbfdb020 614 SUPERFAMILY SSF51735 403 514 1.34E-7 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS07565 1d0945839069ffba270c610fbbfdb020 614 Pfam PF02080 TrkA-C domain 554 608 1.0E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR44_RS01640 a04ca2030747a7dd0900815b05cd4d43 222 Pfam PF01814 Hemerythrin HHE cation binding domain 83 220 4.3E-19 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CWR44_RS01640 a04ca2030747a7dd0900815b05cd4d43 222 SUPERFAMILY SSF140683 1 60 3.66E-6 T 28-03-2018 CWR44_RS01640 a04ca2030747a7dd0900815b05cd4d43 222 Gene3D G3DSA:1.10.3910.10 1 61 2.4E-15 T 28-03-2018 CWR44_RS01640 a04ca2030747a7dd0900815b05cd4d43 222 Hamap MF_01156 Iron-sulfur cluster repair protein ScdA [scdA]. 1 222 50.387 T 28-03-2018 IPR023551 Iron-sulfur cluster repair protein ScdA GO:0006979 CWR44_RS01640 a04ca2030747a7dd0900815b05cd4d43 222 Pfam PF04405 Domain of Unknown function (DUF542) 6 58 2.4E-21 T 28-03-2018 IPR019903 Repair of iron centres family CWR44_RS01640 a04ca2030747a7dd0900815b05cd4d43 222 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 8 221 1.1E-80 T 28-03-2018 IPR019903 Repair of iron centres family CWR44_RS01640 a04ca2030747a7dd0900815b05cd4d43 222 Gene3D G3DSA:1.20.120.520 62 222 2.8E-24 T 28-03-2018 CWR44_RS03075 0dfc167e6b25bc96b46345d7e82d3bb1 160 SUPERFAMILY SSF46785 2 139 6.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03075 0dfc167e6b25bc96b46345d7e82d3bb1 160 Gene3D G3DSA:1.10.10.10 1 147 2.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03075 0dfc167e6b25bc96b46345d7e82d3bb1 160 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CWR44_RS03075 0dfc167e6b25bc96b46345d7e82d3bb1 160 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 136 2.1E-28 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CWR44_RS03075 0dfc167e6b25bc96b46345d7e82d3bb1 160 Pfam PF02082 Transcriptional regulator 1 83 4.4E-22 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CWR44_RS08160 8a66beb8c0de323b509ddbd125d94b65 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.527 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08160 8a66beb8c0de323b509ddbd125d94b65 57 Pfam PF01783 Ribosomal L32p protein family 2 57 2.7E-27 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08160 8a66beb8c0de323b509ddbd125d94b65 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 2.9E-28 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08160 8a66beb8c0de323b509ddbd125d94b65 57 SUPERFAMILY SSF57829 1 55 8.55E-24 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 SUPERFAMILY SSF54686 1 137 5.23E-59 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 Gene3D G3DSA:3.90.1170.10 3 139 5.3E-53 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 3.4E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 3.4E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 3.4E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 3.4E-40 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 7.9E-61 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.0E-51 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00760 37cb9766dcc4b2d3d2ca6a45d47e816c 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 40.058 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS07255 c8b88b08a7cdf1609903ef2268e90708 354 SUPERFAMILY SSF51905 124 298 2.79E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07255 c8b88b08a7cdf1609903ef2268e90708 354 Gene3D G3DSA:3.50.50.60 1 117 0.043 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07255 c8b88b08a7cdf1609903ef2268e90708 354 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 284 2.6E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07255 c8b88b08a7cdf1609903ef2268e90708 354 SUPERFAMILY SSF51905 1 182 1.71E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07255 c8b88b08a7cdf1609903ef2268e90708 354 Gene3D G3DSA:3.50.50.60 118 297 2.4E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS09520 a65ffd8cb6612ab5575d660be7f5952f 171 PIRSF PIRSF002070 1 166 4.9E-27 T 28-03-2018 CWR44_RS09520 a65ffd8cb6612ab5575d660be7f5952f 171 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 171 1.9E-25 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWR44_RS09520 a65ffd8cb6612ab5575d660be7f5952f 171 Gene3D G3DSA:2.40.50.140 1 114 2.2E-26 T 28-03-2018 CWR44_RS09520 a65ffd8cb6612ab5575d660be7f5952f 171 SUPERFAMILY SSF50249 1 171 8.23E-38 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS09520 a65ffd8cb6612ab5575d660be7f5952f 171 Pfam PF00436 Single-strand binding protein family 1 101 8.8E-21 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 Gene3D G3DSA:3.40.50.720 158 337 2.1E-36 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.4E-41 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 1.4E-41 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 1.4E-41 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 1.4E-41 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.4E-41 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 466 2.7E-170 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 SUPERFAMILY SSF51905 7 339 6.71E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 Gene3D G3DSA:3.30.390.30 338 463 1.4E-39 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 6.7E-34 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 Gene3D G3DSA:1.10.287.990 42 109 6.8E-23 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 SUPERFAMILY SSF55424 344 466 4.3E-39 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 Gene3D G3DSA:3.40.50.720 9 41 0.064 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PIRSF PIRSF000350 3 457 2.4E-94 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 1.2E-75 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.2E-75 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 1.2E-75 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.2E-75 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 1.2E-75 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 1.2E-75 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.2E-75 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.2E-75 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 1.2E-75 T 28-03-2018 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CWR44_RS08000 d9868b1cd4940b4296def7724d7210f0 468 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 329 4.8E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04780 9887ab0ad61e11808f3fd1e22c5e4ee5 192 Pfam PF02796 Helix-turn-helix domain of resolvase 140 183 2.8E-17 T 28-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS04780 9887ab0ad61e11808f3fd1e22c5e4ee5 192 SMART SM00857 2 138 2.1E-60 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS04780 9887ab0ad61e11808f3fd1e22c5e4ee5 192 SUPERFAMILY SSF53041 2 138 3.4E-43 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS04780 9887ab0ad61e11808f3fd1e22c5e4ee5 192 SUPERFAMILY SSF46689 140 182 3.05E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS04780 9887ab0ad61e11808f3fd1e22c5e4ee5 192 Pfam PF00239 Resolvase, N terminal domain 3 138 4.5E-45 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS04780 9887ab0ad61e11808f3fd1e22c5e4ee5 192 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CWR44_RS04780 9887ab0ad61e11808f3fd1e22c5e4ee5 192 Gene3D G3DSA:3.40.50.1390 2 106 4.5E-34 T 28-03-2018 CWR44_RS04780 9887ab0ad61e11808f3fd1e22c5e4ee5 192 Gene3D G3DSA:1.10.10.60 134 184 9.2E-13 T 28-03-2018 CWR44_RS04780 9887ab0ad61e11808f3fd1e22c5e4ee5 192 Gene3D G3DSA:1.20.5.40 107 133 7.0E-15 T 28-03-2018 CWR44_RS04780 9887ab0ad61e11808f3fd1e22c5e4ee5 192 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 28-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CWR44_RS08630 8d02e75b99ef74e376695ef3d6771b1b 294 SUPERFAMILY SSF52540 9 265 1.8E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08630 8d02e75b99ef74e376695ef3d6771b1b 294 Gene3D G3DSA:3.40.50.300 12 179 2.6E-32 T 28-03-2018 CWR44_RS08630 8d02e75b99ef74e376695ef3d6771b1b 294 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 279 8.0E-110 T 28-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis CWR44_RS08630 8d02e75b99ef74e376695ef3d6771b1b 294 Pfam PF01926 50S ribosome-binding GTPase 123 204 1.3E-17 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS08630 8d02e75b99ef74e376695ef3d6771b1b 294 Gene3D G3DSA:1.10.1580.10 180 273 6.3E-19 T 28-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain CWR44_RS08630 8d02e75b99ef74e376695ef3d6771b1b 294 PIRSF PIRSF006230 1 284 2.0E-96 T 28-03-2018 IPR016478 GTPase, MTG1 CWR44_RS00050 81828eb754b7ae615c2fcde6fce0f92f 562 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS00050 81828eb754b7ae615c2fcde6fce0f92f 562 Gene3D G3DSA:3.90.350.10 263 498 2.1E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS00050 81828eb754b7ae615c2fcde6fce0f92f 562 Pfam PF01609 Transposase DDE domain 264 515 8.7E-38 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS12880 81828eb754b7ae615c2fcde6fce0f92f 562 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS12880 81828eb754b7ae615c2fcde6fce0f92f 562 Gene3D G3DSA:3.90.350.10 263 498 2.1E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS12880 81828eb754b7ae615c2fcde6fce0f92f 562 Pfam PF01609 Transposase DDE domain 264 515 8.7E-38 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 Gene3D G3DSA:3.50.50.60 193 325 1.4E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PIRSF PIRSF000238 1 507 1.2E-237 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 507 3.5E-235 T 28-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 Gene3D G3DSA:3.50.50.60 438 507 1.6E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 Gene3D G3DSA:3.40.30.10 101 192 0.0026 T 28-03-2018 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 206 482 2.3E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 Gene3D G3DSA:3.50.50.60 326 437 1.2E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 SUPERFAMILY SSF52833 104 191 9.48E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 SUPERFAMILY SSF52833 1 99 1.34E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 Pfam PF13192 Thioredoxin domain 123 188 4.0E-6 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 467 485 5.1E-59 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 343 367 5.1E-59 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 328 340 5.1E-59 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 254 5.1E-59 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 306 314 5.1E-59 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 207 229 5.1E-59 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 433 454 5.1E-59 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 395 411 5.1E-59 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 335 355 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 SUPERFAMILY SSF51905 197 503 2.06E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 Gene3D G3DSA:3.40.30.10 1 92 1.5E-24 T 28-03-2018 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 365 7.6E-38 T 28-03-2018 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 457 479 7.6E-38 T 28-03-2018 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 227 7.6E-38 T 28-03-2018 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 323 7.6E-38 T 28-03-2018 CWR44_RS04865 2fbdb57e2c24ec5ab25ea2d1ca607eae 507 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 431 447 7.6E-38 T 28-03-2018 CWR44_RS05625 9c2b243b9584e2a730aa8a37ef5144f7 122 Gene3D G3DSA:1.20.5.710 2 51 4.2E-17 T 28-03-2018 CWR44_RS05625 9c2b243b9584e2a730aa8a37ef5144f7 122 SUPERFAMILY SSF54736 52 122 7.32E-25 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CWR44_RS05625 9c2b243b9584e2a730aa8a37ef5144f7 122 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 122 2.5E-48 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS05625 9c2b243b9584e2a730aa8a37ef5144f7 122 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 57 122 1.0E-14 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS05625 9c2b243b9584e2a730aa8a37ef5144f7 122 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 56 122 1.2E-29 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS05625 9c2b243b9584e2a730aa8a37ef5144f7 122 Gene3D G3DSA:3.30.1390.10 52 122 1.9E-29 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CWR44_RS05625 9c2b243b9584e2a730aa8a37ef5144f7 122 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 122 25.446 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS05625 9c2b243b9584e2a730aa8a37ef5144f7 122 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 49 4.5E-21 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS05625 9c2b243b9584e2a730aa8a37ef5144f7 122 SUPERFAMILY SSF48300 3 58 2.22E-18 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 Gene3D G3DSA:3.90.650.10 200 378 6.5E-25 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 Gene3D G3DSA:3.90.650.10 567 727 8.7E-17 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 SUPERFAMILY SSF56042 568 725 8.5E-22 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 724 7.5E-296 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 Gene3D G3DSA:3.30.1330.10 414 562 3.3E-42 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 SUPERFAMILY SSF55326 393 562 6.67E-51 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 Gene3D G3DSA:3.30.1330.10 22 199 4.7E-52 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 SUPERFAMILY SSF55326 18 201 5.83E-50 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 729 287.838 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 360 2.6E-33 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 SUPERFAMILY SSF56042 204 425 4.34E-52 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 Pfam PF00586 AIR synthase related protein, N-terminal domain 89 194 1.1E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 Pfam PF00586 AIR synthase related protein, N-terminal domain 452 557 4.4E-21 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWR44_RS07850 107397a75424568f6f94b9a66943cb5d 729 PIRSF PIRSF001587 8 728 1.0E-301 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS04390 f496007336955562b52827a5bac3a596 303 Gene3D G3DSA:1.20.58.390 9 239 0.013 T 28-03-2018 CWR44_RS04390 f496007336955562b52827a5bac3a596 303 Pfam PF09991 Predicted membrane protein (DUF2232) 15 293 2.9E-56 T 28-03-2018 IPR018710 Protein of unknown function DUF2232 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 SUPERFAMILY SSF52540 53 339 5.97E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 Gene3D G3DSA:1.10.10.10 395 515 1.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 Pfam PF00271 Helicase conserved C-terminal domain 218 319 3.8E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 Pfam PF16124 RecQ zinc-binding 333 394 3.7E-9 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 SUPERFAMILY SSF47819 514 589 7.2E-18 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 SMART SM00490 239 320 1.2E-26 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 SMART SM00341 515 588 8.0E-9 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 Pfam PF09382 RQC domain 399 505 1.1E-23 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 Gene3D G3DSA:1.10.150.80 519 591 9.9E-20 T 28-03-2018 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 SUPERFAMILY SSF46785 399 497 2.31E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 Pfam PF00570 HRDC domain 519 585 8.8E-18 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 Gene3D G3DSA:3.40.50.300 1 210 9.2E-34 T 28-03-2018 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 5 453 2.0E-135 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 2 587 3.8E-256 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 SMART SM00487 10 203 2.5E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 Gene3D G3DSA:3.40.50.300 211 394 3.6E-47 T 28-03-2018 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 Pfam PF00270 DEAD/DEAH box helicase 16 178 3.0E-20 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR44_RS06630 8e6fc9fe97cc394c298561deb85847f8 592 SMART SM00956 402 502 5.6E-25 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 Pfam PF00231 ATP synthase 3 287 3.5E-93 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 SUPERFAMILY SSF52943 2 287 1.57E-85 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 Gene3D G3DSA:1.10.287.80 2 41 5.6E-17 T 28-03-2018 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 Gene3D G3DSA:1.10.287.80 240 282 7.4E-15 T 28-03-2018 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 4.7E-101 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 2.3E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 2.3E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 2.3E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 2.3E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 Gene3D G3DSA:3.40.1380.10 42 239 6.8E-70 T 28-03-2018 CWR44_RS00150 c008a5d21e58c111453939cd88dc54c1 288 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 34.76 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS03965 3ae3296725073f1b77a9fb29c2065b43 295 Gene3D G3DSA:2.30.30.60 135 189 7.2E-12 T 28-03-2018 CWR44_RS03965 3ae3296725073f1b77a9fb29c2065b43 295 SUPERFAMILY SSF82861 31 118 5.89E-16 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CWR44_RS03965 3ae3296725073f1b77a9fb29c2065b43 295 SUPERFAMILY SSF50182 120 188 7.19E-11 T 28-03-2018 IPR010920 LSM domain CWR44_RS03965 3ae3296725073f1b77a9fb29c2065b43 295 Gene3D G3DSA:3.30.70.100 191 284 2.0E-7 T 28-03-2018 CWR44_RS03965 3ae3296725073f1b77a9fb29c2065b43 295 SUPERFAMILY SSF82689 196 284 9.55E-7 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CWR44_RS03965 3ae3296725073f1b77a9fb29c2065b43 295 Pfam PF00924 Mechanosensitive ion channel 76 279 2.9E-36 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CWR44_RS08180 31e02991d0f3f7c65349007430990a56 310 SUPERFAMILY SSF53098 93 305 3.95E-48 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS08180 31e02991d0f3f7c65349007430990a56 310 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 5 297 2.5E-65 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CWR44_RS08180 31e02991d0f3f7c65349007430990a56 310 PIRSF PIRSF037748 1 306 3.1E-109 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CWR44_RS08180 31e02991d0f3f7c65349007430990a56 310 Pfam PF11858 Domain of unknown function (DUF3378) 3 76 6.9E-20 T 28-03-2018 IPR024568 Ribonuclease HIII, N-terminal CWR44_RS08180 31e02991d0f3f7c65349007430990a56 310 Gene3D G3DSA:3.30.420.10 91 309 7.4E-38 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS08180 31e02991d0f3f7c65349007430990a56 310 Pfam PF01351 Ribonuclease HII 94 297 3.5E-42 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CWR44_RS08180 31e02991d0f3f7c65349007430990a56 310 Gene3D G3DSA:3.30.310.10 1 68 3.9E-4 T 28-03-2018 CWR44_RS08180 31e02991d0f3f7c65349007430990a56 310 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 305 28.429 T 28-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CWR44_RS00205 416b712077e1396e9fb7f7ca4bfd1ac4 138 SMART SM00226 1 137 3.6E-21 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR44_RS00205 416b712077e1396e9fb7f7ca4bfd1ac4 138 SUPERFAMILY SSF52788 1 134 1.44E-30 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR44_RS00205 416b712077e1396e9fb7f7ca4bfd1ac4 138 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 129 1.2E-25 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR44_RS00205 416b712077e1396e9fb7f7ca4bfd1ac4 138 Gene3D G3DSA:3.40.50.2300 1 136 1.1E-29 T 28-03-2018 CWR44_RS00205 416b712077e1396e9fb7f7ca4bfd1ac4 138 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 39 55 2.8E-12 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR44_RS00205 416b712077e1396e9fb7f7ca4bfd1ac4 138 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 71 86 2.8E-12 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR44_RS00205 416b712077e1396e9fb7f7ca4bfd1ac4 138 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 109 124 2.8E-12 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR44_RS00205 416b712077e1396e9fb7f7ca4bfd1ac4 138 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 2.8E-12 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 Pfam PF03454 MoeA C-terminal region (domain IV) 337 407 1.6E-15 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 Gene3D G3DSA:2.40.340.10 335 410 1.6E-12 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 SUPERFAMILY SSF63882 8 182 2.35E-53 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 Pfam PF00994 Probable molybdopterin binding domain 186 324 4.2E-27 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 6.2E-41 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 Gene3D G3DSA:3.40.980.10 156 334 1.4E-52 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 SMART SM00852 186 324 8.7E-37 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 SUPERFAMILY SSF53218 183 328 1.07E-39 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 SUPERFAMILY SSF63867 333 408 3.79E-15 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 183 320 8.6E-33 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS00905 1cf165ab45c96d05aaa09885a173d7df 419 Gene3D G3DSA:2.170.190.11 51 147 1.9E-24 T 28-03-2018 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 Gene3D G3DSA:1.20.120.430 243 355 5.4E-15 T 28-03-2018 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 Gene3D G3DSA:1.20.120.430 1 67 3.5E-17 T 28-03-2018 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 PIRSF PIRSF006485 2 436 4.9E-177 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 SUPERFAMILY SSF52540 4 167 2.36E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 155 4.4E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 175 343 1.6E-27 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 SUPERFAMILY SSF52540 138 433 1.7E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 Gene3D G3DSA:3.30.300.20 356 434 9.6E-34 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 4.3E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 4.3E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 432 2.1E-31 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 431 3.5E-181 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 Hamap MF_00195 GTPase Der [der]. 3 436 40.876 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 Gene3D G3DSA:1.20.120.430 68 242 1.7E-45 T 28-03-2018 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 5.0E-26 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS10335 4ef91acdc1ad4a1110ca913c6bc23f0a 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 7.5E-27 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 6.9E-71 T 28-03-2018 CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 SUPERFAMILY SSF51735 5 255 1.31E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 Gene3D G3DSA:3.40.50.720 1 40 1.1E-8 T 28-03-2018 CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 Gene3D G3DSA:3.40.50.720 41 265 4.8E-65 T 28-03-2018 CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.0E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.0E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.0E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.0E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.0E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01835 4aa43563705c73cac7ec5730e978ef99 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.0E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS12860 711c584b9a01cf800c080081f6d99d37 503 Gene3D G3DSA:3.40.50.300 3 218 4.9E-59 T 28-03-2018 CWR44_RS12860 711c584b9a01cf800c080081f6d99d37 503 Pfam PF00270 DEAD/DEAH box helicase 26 191 1.1E-50 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR44_RS12860 711c584b9a01cf800c080081f6d99d37 503 Pfam PF00271 Helicase conserved C-terminal domain 226 335 2.0E-30 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS12860 711c584b9a01cf800c080081f6d99d37 503 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 2 502 42.706 T 28-03-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 CWR44_RS12860 711c584b9a01cf800c080081f6d99d37 503 SMART SM00487 21 218 3.4E-60 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS12860 711c584b9a01cf800c080081f6d99d37 503 Gene3D G3DSA:3.40.50.300 219 499 1.6E-45 T 28-03-2018 CWR44_RS12860 711c584b9a01cf800c080081f6d99d37 503 SMART SM00490 254 335 6.5E-34 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS12860 711c584b9a01cf800c080081f6d99d37 503 SUPERFAMILY SSF52540 69 356 1.78E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS12860 711c584b9a01cf800c080081f6d99d37 503 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 148 156 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CWR44_RS11065 b4f099fafbadb55b6e1f4515b3002f18 150 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 144 31.249 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CWR44_RS11065 b4f099fafbadb55b6e1f4515b3002f18 150 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 143 4.5E-51 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CWR44_RS11065 b4f099fafbadb55b6e1f4515b3002f18 150 Gene3D G3DSA:3.50.80.10 1 150 4.5E-51 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CWR44_RS11065 b4f099fafbadb55b6e1f4515b3002f18 150 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 8.4E-52 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CWR44_RS11065 b4f099fafbadb55b6e1f4515b3002f18 150 SUPERFAMILY SSF69500 1 143 5.23E-52 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Pfam PF02151 UvrB/uvrC motif 417 452 1.3E-5 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Gene3D G3DSA:1.10.8.60 714 818 1.9E-26 T 28-03-2018 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Pfam PF07724 AAA domain (Cdc48 subfamily) 536 708 1.1E-56 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 SUPERFAMILY SSF52540 486 798 2.03E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Gene3D G3DSA:1.10.8.60 344 487 2.4E-43 T 28-03-2018 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 SMART SM00382 200 345 1.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 SMART SM00382 537 715 3.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 541 559 7.5E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 662 7.5E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 586 604 7.5E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 615 633 7.5E-43 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.4E-14 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 8.8E-18 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Gene3D G3DSA:1.10.1780.10 79 191 3.3E-24 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 SUPERFAMILY SSF52540 161 464 2.12E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 SMART SM01086 714 803 3.5E-37 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 SUPERFAMILY SSF81923 5 152 2.9E-31 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 571 589 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 334 4.6E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Gene3D G3DSA:1.10.1780.10 1 78 3.0E-22 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Gene3D G3DSA:3.40.50.300 192 342 1.9E-21 T 28-03-2018 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Gene3D G3DSA:3.40.50.300 492 713 6.8E-55 T 28-03-2018 CWR44_RS05540 b46049815627e4bc7f395e87837651d8 824 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 714 793 6.9E-27 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CWR44_RS06680 fe3db2500511ffa2ccf75da8bf63312c 299 Pfam PF00892 EamA-like transporter family 11 142 4.1E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR44_RS06680 fe3db2500511ffa2ccf75da8bf63312c 299 Pfam PF00892 EamA-like transporter family 154 280 1.1E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR44_RS06680 fe3db2500511ffa2ccf75da8bf63312c 299 SUPERFAMILY SSF103481 45 145 5.49E-12 T 28-03-2018 CWR44_RS06680 fe3db2500511ffa2ccf75da8bf63312c 299 SUPERFAMILY SSF103481 185 281 9.02E-15 T 28-03-2018 CWR44_RS04415 1a67efde07da9e350a4713ec3406cf5c 270 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 207 217 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CWR44_RS04415 1a67efde07da9e350a4713ec3406cf5c 270 SUPERFAMILY SSF53613 4 268 4.16E-61 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS04415 1a67efde07da9e350a4713ec3406cf5c 270 Pfam PF01256 Carbohydrate kinase 25 262 2.2E-55 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CWR44_RS04415 1a67efde07da9e350a4713ec3406cf5c 270 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 8 266 1.9E-54 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CWR44_RS04415 1a67efde07da9e350a4713ec3406cf5c 270 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 91 101 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CWR44_RS04415 1a67efde07da9e350a4713ec3406cf5c 270 Gene3D G3DSA:3.40.1190.20 2 270 6.9E-41 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS04415 1a67efde07da9e350a4713ec3406cf5c 270 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 1 270 22.601 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CWR44_RS10645 bbfacb16fc673f5d7da262cb63ebb52d 324 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 196 210 - T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CWR44_RS10645 bbfacb16fc673f5d7da262cb63ebb52d 324 SUPERFAMILY SSF52540 3 320 1.27E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10645 bbfacb16fc673f5d7da262cb63ebb52d 324 Gene3D G3DSA:3.40.50.300 110 323 1.8E-24 T 28-03-2018 CWR44_RS10645 bbfacb16fc673f5d7da262cb63ebb52d 324 Gene3D G3DSA:3.30.450.90 1 105 2.8E-22 T 28-03-2018 CWR44_RS10645 bbfacb16fc673f5d7da262cb63ebb52d 324 Pfam PF00437 Type II/IV secretion system protein 9 265 1.3E-52 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CWR44_RS05510 8098dcf9cba0c6d0c1c910c5e1dbea62 295 SUPERFAMILY SSF51366 19 267 2.78E-71 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR44_RS05510 8098dcf9cba0c6d0c1c910c5e1dbea62 295 PIRSF PIRSF029271 2 295 1.1E-150 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CWR44_RS05510 8098dcf9cba0c6d0c1c910c5e1dbea62 295 ProSitePatterns PS01235 PdxS/SNZ family signature. 206 224 - T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CWR44_RS05510 8098dcf9cba0c6d0c1c910c5e1dbea62 295 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 10 295 5.2E-152 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CWR44_RS05510 8098dcf9cba0c6d0c1c910c5e1dbea62 295 Gene3D G3DSA:3.20.20.70 19 272 2.6E-72 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS05510 8098dcf9cba0c6d0c1c910c5e1dbea62 295 Pfam PF01680 SOR/SNZ family 9 213 6.3E-106 T 28-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CWR44_RS05510 8098dcf9cba0c6d0c1c910c5e1dbea62 295 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 5 295 52.494 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CWR44_RS03145 45d92b682b9639ef42359e58d92ecbbf 400 Gene3D G3DSA:1.20.1250.20 4 196 7.5E-10 T 28-03-2018 CWR44_RS03145 45d92b682b9639ef42359e58d92ecbbf 400 Gene3D G3DSA:1.20.1250.20 200 398 5.5E-17 T 28-03-2018 CWR44_RS03145 45d92b682b9639ef42359e58d92ecbbf 400 Pfam PF05977 Transmembrane secretion effector 10 390 8.0E-16 T 28-03-2018 IPR010290 Transmembrane secretion effector CWR44_RS03145 45d92b682b9639ef42359e58d92ecbbf 400 SUPERFAMILY SSF103473 6 395 5.1E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS04785 f836f520e5924a2d0dee0ba64af93f6b 126 Pfam PF03965 Penicillinase repressor 8 121 1.8E-34 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR44_RS04785 f836f520e5924a2d0dee0ba64af93f6b 126 Gene3D G3DSA:1.10.10.10 9 72 1.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04785 f836f520e5924a2d0dee0ba64af93f6b 126 PIRSF PIRSF019455 1 126 1.4E-31 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CWR44_RS04785 f836f520e5924a2d0dee0ba64af93f6b 126 SUPERFAMILY SSF46785 6 125 6.96E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04785 f836f520e5924a2d0dee0ba64af93f6b 126 Gene3D G3DSA:1.10.4040.10 73 122 6.4E-15 T 28-03-2018 CWR44_RS09870 ab620d4ce5a75e027c415ad3deb9d870 260 SUPERFAMILY SSF51366 34 254 6.83E-69 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR44_RS09870 ab620d4ce5a75e027c415ad3deb9d870 260 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 50 67 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CWR44_RS09870 ab620d4ce5a75e027c415ad3deb9d870 260 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 255 33.652 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CWR44_RS09870 ab620d4ce5a75e027c415ad3deb9d870 260 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 252 1.1E-77 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CWR44_RS09870 ab620d4ce5a75e027c415ad3deb9d870 260 Gene3D G3DSA:3.20.20.70 4 257 1.6E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS06780 6dbf00d85af7a4aa048d2c043b17fd5d 213 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 6 201 7.0E-57 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal CWR44_RS06780 6dbf00d85af7a4aa048d2c043b17fd5d 213 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 1.9E-35 T 28-03-2018 IPR001498 Impact, N-terminal CWR44_RS06780 6dbf00d85af7a4aa048d2c043b17fd5d 213 SUPERFAMILY SSF54980 138 201 2.73E-8 T 28-03-2018 IPR035647 EF-G domain III/V-like CWR44_RS06780 6dbf00d85af7a4aa048d2c043b17fd5d 213 Gene3D G3DSA:3.30.230.30 4 133 3.5E-47 T 28-03-2018 IPR001498 Impact, N-terminal CWR44_RS06780 6dbf00d85af7a4aa048d2c043b17fd5d 213 Gene3D G3DSA:3.30.70.240 137 198 5.8E-12 T 28-03-2018 CWR44_RS06780 6dbf00d85af7a4aa048d2c043b17fd5d 213 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 28-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CWR44_RS06780 6dbf00d85af7a4aa048d2c043b17fd5d 213 SUPERFAMILY SSF54211 5 131 1.67E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS06780 6dbf00d85af7a4aa048d2c043b17fd5d 213 Pfam PF09186 Domain of unknown function (DUF1949) 140 195 1.8E-12 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 Pfam PF08245 Mur ligase middle domain 106 274 2.1E-25 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 Gene3D G3DSA:3.90.190.20 296 436 1.6E-24 T 28-03-2018 CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 SUPERFAMILY SSF53623 87 293 9.16E-58 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 SUPERFAMILY SSF51984 1 88 3.34E-20 T 28-03-2018 CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 433 34.705 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 SUPERFAMILY SSF53244 294 429 1.26E-34 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 Gene3D G3DSA:3.40.50.720 4 89 2.8E-4 T 28-03-2018 CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 Pfam PF01225 Mur ligase family, catalytic domain 3 101 4.7E-22 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 Gene3D G3DSA:3.40.1190.10 90 295 2.3E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 376 2.4E-19 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR44_RS11570 2e70ddba537c6a38bb6668a565604304 437 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 3 428 2.9E-126 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 Pfam PF13365 Trypsin-like peptidase domain 127 271 2.0E-30 T 28-03-2018 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 Gene3D G3DSA:2.40.10.10 197 303 5.2E-34 T 28-03-2018 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 Gene3D G3DSA:2.40.10.10 81 196 3.2E-29 T 28-03-2018 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 SUPERFAMILY SSF50494 85 305 1.35E-54 T 28-03-2018 IPR009003 Peptidase S1, PA clan CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 PRINTS PR00834 HtrA/DegQ protease family signature 264 281 2.0E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 PRINTS PR00834 HtrA/DegQ protease family signature 347 359 2.0E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 PRINTS PR00834 HtrA/DegQ protease family signature 201 225 2.0E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 PRINTS PR00834 HtrA/DegQ protease family signature 160 180 2.0E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 PRINTS PR00834 HtrA/DegQ protease family signature 242 259 2.0E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 PRINTS PR00834 HtrA/DegQ protease family signature 139 151 2.0E-35 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 SMART SM00228 309 390 3.5E-4 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 Gene3D G3DSA:2.30.42.10 307 413 2.5E-18 T 28-03-2018 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 Pfam PF13180 PDZ domain 311 399 1.6E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS11505 6f13973434d15da54e56c3e216f35099 425 SUPERFAMILY SSF50156 283 401 3.02E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS09875 91b07abc7e9afe0f8738f9aba76e111a 208 Gene3D G3DSA:3.20.20.70 1 207 3.7E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS09875 91b07abc7e9afe0f8738f9aba76e111a 208 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 207 33.705 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CWR44_RS09875 91b07abc7e9afe0f8738f9aba76e111a 208 SUPERFAMILY SSF51366 1 205 1.88E-47 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR44_RS09875 91b07abc7e9afe0f8738f9aba76e111a 208 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 203 1.1E-38 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CWR44_RS04055 6454d9bdb24aed7f2c43f32f63d752d9 558 PIRSF PIRSF001294 1 558 2.5E-226 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CWR44_RS04055 6454d9bdb24aed7f2c43f32f63d752d9 558 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 2 554 6.9E-178 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CWR44_RS04055 6454d9bdb24aed7f2c43f32f63d752d9 558 Pfam PF03814 Potassium-transporting ATPase A subunit 5 554 2.6E-216 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CWR44_RS04055 6454d9bdb24aed7f2c43f32f63d752d9 558 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 556 29.557 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.8E-18 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.8E-18 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.8E-18 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.8E-18 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.8E-18 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 2.4E-12 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 2.4E-12 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 2.4E-12 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.4E-12 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 SUPERFAMILY SSF55124 511 616 1.96E-24 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 281 5.0E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 Gene3D G3DSA:3.50.50.60 243 312 4.5E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00397 Sirohaem Fe-binding site signature 628 646 4.5E-5 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PRINTS PR00397 Sirohaem Fe-binding site signature 671 689 4.5E-5 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 PIRSF PIRSF037149 1 803 0.0 T 28-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 554 615 1.4E-10 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 SUPERFAMILY SSF56014 627 795 5.5E-46 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 624 760 2.1E-24 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 Gene3D G3DSA:3.90.480.10 427 620 4.1E-13 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 Gene3D G3DSA:3.30.413.10 623 800 1.2E-36 T 28-03-2018 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 SUPERFAMILY SSF51905 144 305 5.28E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 792 1.4E-275 T 28-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 Gene3D G3DSA:3.50.50.60 1 103 2.1E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 Gene3D G3DSA:3.50.50.60 104 241 3.3E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 SUPERFAMILY SSF51905 2 192 8.52E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 671 687 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 Pfam PF04324 BFD-like [2Fe-2S] binding domain 415 464 1.0E-15 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CWR44_RS01525 9aaab6ffa664ea66b508d2fd06088b2c 803 Pfam PF04324 BFD-like [2Fe-2S] binding domain 479 529 1.6E-11 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CWR44_RS07595 dff95fee31ce17834dc4c729b51ddb48 391 SUPERFAMILY SSF53756 6 370 2.9E-41 T 28-03-2018 CWR44_RS07595 dff95fee31ce17834dc4c729b51ddb48 391 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 19 179 1.3E-42 T 28-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CWR44_RS07595 dff95fee31ce17834dc4c729b51ddb48 391 Gene3D G3DSA:3.40.50.2000 183 361 3.1E-19 T 28-03-2018 CWR44_RS07595 dff95fee31ce17834dc4c729b51ddb48 391 Gene3D G3DSA:3.40.50.2000 1 182 2.2E-8 T 28-03-2018 CWR44_RS07595 dff95fee31ce17834dc4c729b51ddb48 391 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 227 349 8.5E-9 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWR44_RS07595 dff95fee31ce17834dc4c729b51ddb48 391 Hamap MF_01280 Processive diacylglycerol beta-glucosyltransferase [ugtP]. 2 388 49.201 T 28-03-2018 IPR023589 Processive diacylglycerol beta-glucosyltransferase GO:0047228 KEGG: 00561+2.4.1.315|MetaCyc: PWY-6778|MetaCyc: PWY-7817 CWR44_RS02425 47acdd7969c942b283f6a3f8ff38d3d5 445 Gene3D G3DSA:3.40.640.10 194 313 2.8E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS02425 47acdd7969c942b283f6a3f8ff38d3d5 445 Gene3D G3DSA:3.90.1150.10 1 193 3.0E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS02425 47acdd7969c942b283f6a3f8ff38d3d5 445 SUPERFAMILY SSF53383 20 429 7.01E-128 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS02425 47acdd7969c942b283f6a3f8ff38d3d5 445 Pfam PF00202 Aminotransferase class-III 25 427 1.0E-103 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS02425 47acdd7969c942b283f6a3f8ff38d3d5 445 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 244 281 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS02425 47acdd7969c942b283f6a3f8ff38d3d5 445 Gene3D G3DSA:3.90.1150.10 314 431 8.6E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS02425 47acdd7969c942b283f6a3f8ff38d3d5 445 PIRSF PIRSF000521 3 129 4.3E-6 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS02425 47acdd7969c942b283f6a3f8ff38d3d5 445 PIRSF PIRSF000521 125 430 3.3E-37 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS08875 61f2ee3095e7de1a678ead5402c1e101 514 Pfam PF00919 Uncharacterized protein family UPF0004 70 170 1.1E-30 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CWR44_RS08875 61f2ee3095e7de1a678ead5402c1e101 514 SMART SM00729 213 431 1.4E-62 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR44_RS08875 61f2ee3095e7de1a678ead5402c1e101 514 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 70 502 4.4E-195 T 28-03-2018 CWR44_RS08875 61f2ee3095e7de1a678ead5402c1e101 514 Pfam PF04055 Radical SAM superfamily 217 388 9.0E-34 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS08875 61f2ee3095e7de1a678ead5402c1e101 514 Pfam PF01938 TRAM domain 443 503 1.1E-12 T 28-03-2018 IPR002792 TRAM domain CWR44_RS08875 61f2ee3095e7de1a678ead5402c1e101 514 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 68 504 70.833 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CWR44_RS08875 61f2ee3095e7de1a678ead5402c1e101 514 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 69 501 7.2E-162 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CWR44_RS08875 61f2ee3095e7de1a678ead5402c1e101 514 Gene3D G3DSA:3.80.30.20 210 445 7.8E-54 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CWR44_RS08875 61f2ee3095e7de1a678ead5402c1e101 514 SUPERFAMILY SSF102114 200 436 5.89E-61 T 28-03-2018 CWR44_RS08875 61f2ee3095e7de1a678ead5402c1e101 514 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 217 237 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 Pfam PF14698 Argininosuccinate lyase C-terminal 365 432 1.1E-22 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 Gene3D G3DSA:1.10.275.10 4 108 1.2E-39 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 SUPERFAMILY SSF48557 8 459 3.61E-149 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 2.4E-29 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 2.4E-29 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 2.4E-29 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 PRINTS PR00149 Fumarate lyase superfamily signature 233 260 2.4E-29 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 TIGRFAM TIGR00838 argH: argininosuccinate lyase 6 455 2.9E-198 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 PRINTS PR00145 Argininosuccinate lyase family signature 233 257 4.0E-67 T 28-03-2018 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 4.0E-67 T 28-03-2018 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 4.0E-67 T 28-03-2018 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 PRINTS PR00145 Argininosuccinate lyase family signature 312 331 4.0E-67 T 28-03-2018 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 4.0E-67 T 28-03-2018 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 4.0E-67 T 28-03-2018 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 455 43.062 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 Gene3D G3DSA:1.20.200.10 109 376 2.3E-90 T 28-03-2018 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 Gene3D G3DSA:1.10.40.30 377 434 1.9E-22 T 28-03-2018 CWR44_RS07370 0f0cf816e28487a91fa089a6d9a349af 460 Pfam PF00206 Lyase 8 302 5.6E-73 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CWR44_RS02620 627df5893989368ae19366264894b0d0 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 174 332 9.7E-53 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 433 561 8.4E-4 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 Gene3D G3DSA:3.30.413.10 429 565 4.4E-29 T 28-03-2018 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 Gene3D G3DSA:3.30.413.10 143 348 3.3E-57 T 28-03-2018 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 SUPERFAMILY SSF56014 431 562 2.49E-36 T 28-03-2018 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 Gene3D G3DSA:3.30.413.10 80 142 0.0041 T 28-03-2018 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 20 562 1.1E-264 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 PRINTS PR00397 Sirohaem Fe-binding site signature 481 499 1.1E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 PRINTS PR00397 Sirohaem Fe-binding site signature 433 451 1.1E-8 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 SUPERFAMILY SSF55124 15 148 2.94E-31 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 SUPERFAMILY SSF55124 348 424 9.16E-21 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 SUPERFAMILY SSF56014 149 346 5.89E-62 T 28-03-2018 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 11 573 57.872 T 28-03-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 79 139 3.2E-15 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 355 419 9.9E-14 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS02620 627df5893989368ae19366264894b0d0 573 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 481 497 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CWR44_RS06455 7d4ef20d4d3cd0a3788905af401a574b 543 Gene3D G3DSA:3.40.50.300 310 541 5.7E-56 T 28-03-2018 CWR44_RS06455 7d4ef20d4d3cd0a3788905af401a574b 543 Pfam PF00005 ABC transporter 341 477 3.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06455 7d4ef20d4d3cd0a3788905af401a574b 543 Pfam PF00664 ABC transporter transmembrane region 19 263 1.2E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR44_RS06455 7d4ef20d4d3cd0a3788905af401a574b 543 Gene3D G3DSA:1.20.1560.10 1 309 1.5E-24 T 28-03-2018 CWR44_RS06455 7d4ef20d4d3cd0a3788905af401a574b 543 SMART SM00382 349 531 8.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS06455 7d4ef20d4d3cd0a3788905af401a574b 543 SUPERFAMILY SSF52540 317 528 7.5E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06455 7d4ef20d4d3cd0a3788905af401a574b 543 SUPERFAMILY SSF90123 2 305 8.5E-36 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR44_RS06455 7d4ef20d4d3cd0a3788905af401a574b 543 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS11730 b07e7bd4dbe81deb4ed5d4bd622c61b5 210 SUPERFAMILY SSF63380 92 195 1.36E-28 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CWR44_RS11730 b07e7bd4dbe81deb4ed5d4bd622c61b5 210 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 197 4.2E-64 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11730 b07e7bd4dbe81deb4ed5d4bd622c61b5 210 SUPERFAMILY SSF63380 1 88 4.17E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CWR44_RS11730 b07e7bd4dbe81deb4ed5d4bd622c61b5 210 Pfam PF00677 Lumazine binding domain 100 183 9.0E-20 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11730 b07e7bd4dbe81deb4ed5d4bd622c61b5 210 Pfam PF00677 Lumazine binding domain 3 86 1.4E-20 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11730 b07e7bd4dbe81deb4ed5d4bd622c61b5 210 Gene3D G3DSA:2.40.30.20 93 190 2.7E-28 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS11730 b07e7bd4dbe81deb4ed5d4bd622c61b5 210 PIRSF PIRSF000498 1 207 2.5E-69 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11730 b07e7bd4dbe81deb4ed5d4bd622c61b5 210 Gene3D G3DSA:2.40.30.20 1 88 3.3E-26 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS01325 c07cc56a208812246ab6358ab2f1f192 492 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 491 53.079 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS01325 c07cc56a208812246ab6358ab2f1f192 492 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 487 4.5E-214 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS01325 c07cc56a208812246ab6358ab2f1f192 492 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 490 2.1E-230 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS01325 c07cc56a208812246ab6358ab2f1f192 492 SUPERFAMILY SSF51905 7 274 1.97E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01325 c07cc56a208812246ab6358ab2f1f192 492 Gene3D G3DSA:3.50.50.60 1 437 1.6E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS08190 51fa441ec1b5b9ecfe3d682f485830b4 173 Pfam PF02674 Colicin V production protein 3 160 3.8E-22 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 PIRSF PIRSF000110 1 493 8.4E-182 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 491 82.251 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 9 491 5.3E-191 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 223 240 2.0E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 332 358 2.0E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 147 160 2.0E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 241 257 2.0E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 171 199 2.0E-47 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 14 191 8.1E-61 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 Gene3D G3DSA:3.30.360.10 193 492 2.6E-120 T 28-03-2018 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 Gene3D G3DSA:3.40.50.720 7 192 2.0E-67 T 28-03-2018 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 SUPERFAMILY SSF51735 7 194 8.07E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 SUPERFAMILY SSF55347 181 491 2.32E-110 T 28-03-2018 CWR44_RS10455 495a0d99529953ed96ef41db32edfc67 494 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 194 489 1.4E-111 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CWR44_RS09945 b6f091f59ebb2ef72ac4afd97bb31ed2 316 Gene3D G3DSA:3.40.190.10 40 166 1.7E-36 T 28-03-2018 CWR44_RS09945 b6f091f59ebb2ef72ac4afd97bb31ed2 316 Gene3D G3DSA:3.40.190.10 167 312 1.2E-18 T 28-03-2018 CWR44_RS09945 b6f091f59ebb2ef72ac4afd97bb31ed2 316 Pfam PF12849 PBP superfamily domain 38 282 1.3E-41 T 28-03-2018 IPR024370 PBP domain CWR44_RS09945 b6f091f59ebb2ef72ac4afd97bb31ed2 316 SUPERFAMILY SSF53850 43 308 1.93E-70 T 28-03-2018 CWR44_RS09945 b6f091f59ebb2ef72ac4afd97bb31ed2 316 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 294 3.6E-98 T 28-03-2018 IPR011862 Phosphate binding protein GO:0006810 CWR44_RS06875 73fb05e29d7b3e70657eb2b349c0c95f 328 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 6 314 2.0E-125 T 28-03-2018 IPR010119 Gluconeogenesis factor CWR44_RS06875 73fb05e29d7b3e70657eb2b349c0c95f 328 SUPERFAMILY SSF142338 3 312 1.96E-101 T 28-03-2018 CWR44_RS06875 73fb05e29d7b3e70657eb2b349c0c95f 328 Gene3D G3DSA:3.40.50.10680 82 322 7.5E-59 T 28-03-2018 CWR44_RS06875 73fb05e29d7b3e70657eb2b349c0c95f 328 Pfam PF01933 Uncharacterised protein family UPF0052 6 287 3.4E-106 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CWR44_RS06875 73fb05e29d7b3e70657eb2b349c0c95f 328 Hamap MF_00973 Gluconeogenesis factor. 2 317 33.939 T 28-03-2018 IPR010119 Gluconeogenesis factor CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 2 391 50.729 T 28-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 197 5.8E-78 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 197 5.4E-70 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 208 393 3.0E-69 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 203 393 35.622 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 202 36.715 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 Gene3D G3DSA:3.90.870.10 1 211 1.2E-85 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 Pfam PF00925 GTP cyclohydrolase II 209 369 3.7E-63 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 PIRSF PIRSF001259 1 393 3.7E-147 T 28-03-2018 CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 SUPERFAMILY SSF55821 2 199 6.64E-77 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWR44_RS11725 1a070cc8a0a18ebb73ab45a023298318 393 SUPERFAMILY SSF142695 205 371 2.48E-57 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 7.4E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 7.4E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 7.4E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 7.4E-31 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 SUPERFAMILY SSF51569 2 289 2.2E-84 T 28-03-2018 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 PIRSF PIRSF001365 2 293 9.8E-85 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 Pfam PF00701 Dihydrodipicolinate synthetase family 5 279 4.0E-78 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 8 287 4.0E-86 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 SMART SM01130 4 290 6.8E-111 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 Gene3D G3DSA:3.20.20.70 2 293 2.1E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS09970 dc670d3418be226c330239ce06ea2301 294 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 4 288 54.031 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 4 250 8.5E-79 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 SUPERFAMILY SSF53613 2 259 3.43E-58 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 6 254 30.035 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 PIRSF PIRSF000513 1 262 4.4E-88 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 Gene3D G3DSA:3.40.1190.20 1 263 4.3E-55 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 Pfam PF02110 Hydroxyethylthiazole kinase family 4 248 1.0E-77 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 56 64 6.0E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 25 46 6.0E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 12 19 6.0E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 82 99 6.0E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 113 127 6.0E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00095 2f207fb2b9f9ccb2608b4daffb091901 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 156 173 6.0E-34 T 28-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS09745 762b4d1945eacad5d974f8d348ae09e4 574 SUPERFAMILY SSF54001 222 353 5.0E-10 T 28-03-2018 CWR44_RS09745 762b4d1945eacad5d974f8d348ae09e4 574 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 31 164 2.0E-13 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS09745 762b4d1945eacad5d974f8d348ae09e4 574 SUPERFAMILY SSF55846 28 170 4.32E-24 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS09745 762b4d1945eacad5d974f8d348ae09e4 574 SMART SM00644 21 164 2.0E-7 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS09745 762b4d1945eacad5d974f8d348ae09e4 574 Gene3D G3DSA:3.40.80.10 18 201 6.4E-22 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS09745 762b4d1945eacad5d974f8d348ae09e4 574 Pfam PF05257 CHAP domain 240 327 1.2E-8 T 28-03-2018 IPR007921 CHAP domain CWR44_RS06660 4a492a782fef395c8bfb6f6000043aaa 308 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 10 301 4.6E-52 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CWR44_RS06660 4a492a782fef395c8bfb6f6000043aaa 308 Gene3D G3DSA:3.40.50.10330 4 140 1.2E-21 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CWR44_RS06660 4a492a782fef395c8bfb6f6000043aaa 308 SMART SM00046 7 139 0.0015 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CWR44_RS06660 4a492a782fef395c8bfb6f6000043aaa 308 Pfam PF00781 Diacylglycerol kinase catalytic domain 8 135 1.5E-25 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CWR44_RS06660 4a492a782fef395c8bfb6f6000043aaa 308 SUPERFAMILY SSF111331 6 303 4.06E-60 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CWR44_RS03870 9f08928252b0f1845b96fdcf283c1f20 247 SUPERFAMILY SSF52540 2 225 2.71E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03870 9f08928252b0f1845b96fdcf283c1f20 247 SMART SM00382 27 212 2.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03870 9f08928252b0f1845b96fdcf283c1f20 247 Pfam PF00005 ABC transporter 17 162 3.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS03870 9f08928252b0f1845b96fdcf283c1f20 247 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS03870 9f08928252b0f1845b96fdcf283c1f20 247 Gene3D G3DSA:3.40.50.300 1 242 5.4E-48 T 28-03-2018 CWR44_RS11690 06e8e5f8b5340db2b66b82a3a53e0ae1 186 Pfam PF06962 Putative rRNA methylase 47 184 1.0E-46 T 28-03-2018 IPR010719 Putative rRNA methylase CWR44_RS11690 06e8e5f8b5340db2b66b82a3a53e0ae1 186 SUPERFAMILY SSF53335 15 185 5.67E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS11690 06e8e5f8b5340db2b66b82a3a53e0ae1 186 Gene3D G3DSA:3.40.50.150 4 186 1.3E-22 T 28-03-2018 CWR44_RS00785 529bd2525ffdc8303c020888079ec528 91 Gene3D G3DSA:3.30.70.330 1 91 6.8E-31 T 28-03-2018 CWR44_RS00785 529bd2525ffdc8303c020888079ec528 91 Pfam PF00276 Ribosomal protein L23 5 86 1.8E-31 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00785 529bd2525ffdc8303c020888079ec528 91 SUPERFAMILY SSF54189 1 86 2.45E-30 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00785 529bd2525ffdc8303c020888079ec528 91 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 91 20.168 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CWR44_RS02220 8ee64e83e1349a4746d2b013cc7ab9f6 316 Gene3D G3DSA:1.20.58.340 131 245 4.7E-11 T 28-03-2018 CWR44_RS02220 8ee64e83e1349a4746d2b013cc7ab9f6 316 Gene3D G3DSA:1.20.58.340 246 316 2.1E-21 T 28-03-2018 CWR44_RS02220 8ee64e83e1349a4746d2b013cc7ab9f6 316 Pfam PF01544 CorA-like Mg2+ transporter protein 27 311 7.9E-57 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CWR44_RS02220 8ee64e83e1349a4746d2b013cc7ab9f6 316 Gene3D G3DSA:3.30.460.20 1 125 5.9E-17 T 28-03-2018 CWR44_RS02220 8ee64e83e1349a4746d2b013cc7ab9f6 316 SUPERFAMILY SSF144083 251 313 7.72E-20 T 28-03-2018 CWR44_RS02220 8ee64e83e1349a4746d2b013cc7ab9f6 316 SUPERFAMILY SSF143865 6 250 1.2E-37 T 28-03-2018 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 530 652 1.8E-49 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 531 651 5.0E-43 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 404 486 9.4E-23 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 Pfam PF00367 phosphotransferase system, EIIB 431 462 4.6E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 Gene3D G3DSA:2.70.70.10 520 675 7.3E-56 T 28-03-2018 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 Gene3D G3DSA:3.30.1360.60 426 500 2.7E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 593 605 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 Pfam PF02378 Phosphotransferase system, EIIC 13 344 3.9E-96 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 SUPERFAMILY SSF51261 524 673 1.08E-51 T 28-03-2018 IPR011055 Duplicated hybrid motif CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 502 3.4E-241 T 28-03-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 440 457 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS02155 2f6dcc1047dc0abadcbcd3331f534d6b 675 SUPERFAMILY SSF55604 429 500 1.44E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS06165 4eb4d2c76c230bb4e91bf5c2c58a9e62 160 PIRSF PIRSF019239 1 160 2.2E-31 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CWR44_RS06165 4eb4d2c76c230bb4e91bf5c2c58a9e62 160 Pfam PF01899 Na+/H+ ion antiporter subunit 8 158 2.1E-32 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 Pfam PF13646 HEAT repeats 299 370 3.1E-8 T 28-03-2018 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 SMART SM00567 E-Z type HEAT repeats 329 358 0.49 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 SMART SM00567 E-Z type HEAT repeats 297 326 74.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 Pfam PF13484 4Fe-4S double cluster binding domain 188 250 1.7E-14 T 28-03-2018 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 Gene3D G3DSA:3.30.70.20 54 193 3.2E-4 T 28-03-2018 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 10 341 5.1E-122 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 308 42.586 T 28-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 SUPERFAMILY SSF54862 164 261 1.3E-13 T 28-03-2018 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 Gene3D G3DSA:1.25.40.70 258 371 3.9E-7 T 28-03-2018 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 Gene3D G3DSA:3.30.70.20 194 251 3.3E-8 T 28-03-2018 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 3.5E-18 T 28-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CWR44_RS12005 cb793b85ea00155f70990783a4778982 375 SUPERFAMILY SSF48371 284 371 1.01E-10 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CWR44_RS08450 14206d58546cb337960456fdf57da8df 565 Gene3D G3DSA:3.40.970.40 238 288 5.4E-12 T 28-03-2018 CWR44_RS08450 14206d58546cb337960456fdf57da8df 565 Gene3D G3DSA:1.10.8.50 166 235 6.5E-18 T 28-03-2018 CWR44_RS08450 14206d58546cb337960456fdf57da8df 565 Gene3D G3DSA:2.30.310.10 1 165 1.3E-47 T 28-03-2018 CWR44_RS08450 14206d58546cb337960456fdf57da8df 565 Pfam PF05670 Domain of unknown function (DUF814) 449 533 1.9E-26 T 28-03-2018 IPR008532 Domain of unknown function DUF814 CWR44_RS08450 14206d58546cb337960456fdf57da8df 565 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 441 8.0E-137 T 28-03-2018 CWR44_RS00165 991c54bc07ebf677d086422775b1d453 176 Pfam PF00430 ATP synthase B/B' CF(0) 24 153 7.2E-34 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CWR44_RS00165 991c54bc07ebf677d086422775b1d453 176 Hamap MF_01398 ATP synthase subunit b [atpF]. 18 155 13.539 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CWR44_RS00165 991c54bc07ebf677d086422775b1d453 176 Gene3D G3DSA:1.20.5.620 58 139 2.0E-4 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CWR44_RS00165 991c54bc07ebf677d086422775b1d453 176 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 28 172 4.0E-37 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CWR44_RS00165 991c54bc07ebf677d086422775b1d453 176 SUPERFAMILY SSF81573 79 137 2.35E-7 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CWR44_RS08280 06a7d2dc9183d21361b62b433ec250bf 230 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 225 2.9E-63 T 28-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CWR44_RS08280 06a7d2dc9183d21361b62b433ec250bf 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 199 2.2E-23 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS08280 06a7d2dc9183d21361b62b433ec250bf 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 194 5.6E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS08280 06a7d2dc9183d21361b62b433ec250bf 230 SUPERFAMILY SSF56784 2 228 2.28E-45 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS08280 06a7d2dc9183d21361b62b433ec250bf 230 Gene3D G3DSA:3.40.50.1000 89 230 3.8E-28 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS08280 06a7d2dc9183d21361b62b433ec250bf 230 Gene3D G3DSA:1.10.150.240 17 88 3.7E-15 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 1.0E-138 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 Gene3D G3DSA:2.40.50.140 1 114 9.7E-49 T 28-03-2018 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 6.4E-57 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 SUPERFAMILY SSF50249 2 125 1.47E-50 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 SUPERFAMILY SSF50104 126 272 3.55E-60 T 28-03-2018 IPR008991 Translation protein SH3-like domain CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 Gene3D G3DSA:4.10.950.10 197 275 3.5E-32 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 6.5E-34 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 PIRSF PIRSF002158 3 277 2.3E-101 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 Gene3D G3DSA:2.30.30.30 119 195 8.0E-35 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 49.125 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 SMART SM01383 42 118 3.3E-46 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00780 03ba3882a5bf85e142e609746d9138f2 277 SMART SM01382 124 253 1.0E-93 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR44_RS09950 2e7d185af9e00450871395ced0793273 299 Pfam PF13509 S1 domain 8 69 5.0E-6 T 28-03-2018 CWR44_RS09950 2e7d185af9e00450871395ced0793273 299 Gene3D G3DSA:2.40.50.140 72 228 5.1E-7 T 28-03-2018 CWR44_RS09950 2e7d185af9e00450871395ced0793273 299 PIRSF PIRSF012524 4 290 1.6E-108 T 28-03-2018 IPR014464 Conserved virulence factor B CWR44_RS09950 2e7d185af9e00450871395ced0793273 299 Pfam PF00575 S1 RNA binding domain 82 211 2.7E-4 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS09950 2e7d185af9e00450871395ced0793273 299 Gene3D G3DSA:1.10.10.10 229 288 1.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10150 ef312f504292c78325d258bc2c533540 64 Pfam PF10782 Zinc-finger 8 64 2.7E-27 T 28-03-2018 IPR019718 Protein of unknown function DUF2602 CWR44_RS11010 081158cd043d3776bca6c2516842eb6d 379 SUPERFAMILY SSF53383 3 374 2.18E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS11010 081158cd043d3776bca6c2516842eb6d 379 Pfam PF00266 Aminotransferase class-V 3 364 3.5E-77 T 28-03-2018 IPR000192 Aminotransferase class V domain CWR44_RS11010 081158cd043d3776bca6c2516842eb6d 379 Gene3D G3DSA:3.90.1150.10 263 379 1.5E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS11010 081158cd043d3776bca6c2516842eb6d 379 Gene3D G3DSA:3.40.640.10 11 255 5.8E-59 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS11010 081158cd043d3776bca6c2516842eb6d 379 PIRSF PIRSF005572 1 379 2.2E-123 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWR44_RS12245 05d0173a1ad77ab92fa4906cf557d79c 270 Hamap MF_01434 Monofunctional glycosyltransferase [mgt]. 1 269 52.379 T 28-03-2018 IPR022978 Monofunctional glycosyl transferase GO:0016757 CWR44_RS12245 05d0173a1ad77ab92fa4906cf557d79c 270 SUPERFAMILY SSF53955 76 265 3.09E-57 T 28-03-2018 IPR023346 Lysozyme-like domain CWR44_RS12245 05d0173a1ad77ab92fa4906cf557d79c 270 Gene3D G3DSA:1.10.3810.10 61 268 6.7E-64 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWR44_RS12245 05d0173a1ad77ab92fa4906cf557d79c 270 Pfam PF00912 Transglycosylase 76 250 3.9E-55 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWR44_RS01380 7c1fd4611cbf2d6d61e6cc14382f4941 133 SUPERFAMILY SSF55729 8 126 3.66E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS01380 7c1fd4611cbf2d6d61e6cc14382f4941 133 Gene3D G3DSA:3.40.630.30 1 133 4.6E-19 T 28-03-2018 CWR44_RS01380 7c1fd4611cbf2d6d61e6cc14382f4941 133 Pfam PF13673 Acetyltransferase (GNAT) domain 38 125 1.9E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 SMART SM00889 479 597 2.2E-70 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Hamap MF_00054_B Elongation factor G [fusA]. 6 690 107.925 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 SUPERFAMILY SSF52540 6 280 1.17E-109 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Pfam PF03144 Elongation factor Tu domain 2 323 390 1.2E-14 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 SUPERFAMILY SSF54980 599 689 6.23E-31 T 28-03-2018 IPR035647 EF-G domain III/V-like CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Gene3D G3DSA:3.30.230.10 491 612 2.5E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Gene3D G3DSA:3.30.70.240 613 690 1.6E-32 T 28-03-2018 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Gene3D G3DSA:3.30.70.870 400 490 7.3E-34 T 28-03-2018 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Gene3D G3DSA:3.40.50.300 1 285 1.4E-64 T 28-03-2018 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 SUPERFAMILY SSF54211 478 598 1.16E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Gene3D G3DSA:2.40.30.10 286 399 7.3E-31 T 28-03-2018 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Pfam PF03764 Elongation factor G, domain IV 478 596 4.6E-45 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Pfam PF14492 Elongation Factor G, domain II 403 476 6.0E-33 T 28-03-2018 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 7.8E-43 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 691 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 SUPERFAMILY SSF54980 403 480 2.09E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Pfam PF00009 Elongation factor Tu GTP binding domain 8 280 3.0E-69 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 SMART SM00838 599 686 2.9E-57 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 SUPERFAMILY SSF50447 263 403 7.07E-34 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWR44_RS05660 a35c0b84fca3df7a7d5736c6ff698178 693 Pfam PF00679 Elongation factor G C-terminus 599 685 2.0E-31 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR44_RS13200 e05ee154a8bede130fc48913221b4bcc 317 Pfam PF06970 Replication initiator protein A (RepA) N-terminus 13 87 3.0E-31 T 28-03-2018 IPR010724 Replication initiator A, N-terminal CWR44_RS13070 e05ee154a8bede130fc48913221b4bcc 317 Pfam PF06970 Replication initiator protein A (RepA) N-terminus 13 87 3.0E-31 T 28-03-2018 IPR010724 Replication initiator A, N-terminal CWR44_RS11060 68cfe215d5e450c67ce2b20f48ee15a5 291 Pfam PF08239 Bacterial SH3 domain 52 101 1.0E-9 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CWR44_RS11060 68cfe215d5e450c67ce2b20f48ee15a5 291 SUPERFAMILY SSF53187 119 289 8.48E-48 T 28-03-2018 CWR44_RS11060 68cfe215d5e450c67ce2b20f48ee15a5 291 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 122 286 1.2E-42 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR44_RS11060 68cfe215d5e450c67ce2b20f48ee15a5 291 SMART SM00646 178 286 1.2E-31 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CWR44_RS11060 68cfe215d5e450c67ce2b20f48ee15a5 291 Gene3D G3DSA:3.40.630.40 117 291 6.6E-51 T 28-03-2018 CWR44_RS11060 68cfe215d5e450c67ce2b20f48ee15a5 291 Gene3D G3DSA:2.40.50.110 37 105 1.9E-10 T 28-03-2018 CWR44_RS11060 68cfe215d5e450c67ce2b20f48ee15a5 291 PIRSF PIRSF037730 7 291 3.0E-132 T 28-03-2018 IPR017273 Probable cell wall amidase LytH GO:0005576|GO:0016811|GO:0071555 CWR44_RS11060 68cfe215d5e450c67ce2b20f48ee15a5 291 SMART SM00287 41 105 1.8E-10 T 28-03-2018 IPR003646 SH3-like domain, bacterial-type CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 Gene3D G3DSA:1.10.10.10 79 97 2.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 SMART SM00028 172 206 6.5E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 SMART SM00028 35 68 0.89 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 SMART SM00028 103 136 50.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 SMART SM00028 69 102 0.011 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 SMART SM00028 138 171 11.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 Gene3D G3DSA:1.25.40.10 9 46 0.0075 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 Gene3D G3DSA:1.25.40.10 47 78 1.5E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 SUPERFAMILY SSF48452 13 207 6.45E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 Pfam PF13181 Tetratricopeptide repeat 173 206 6.4E-7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 Pfam PF13431 Tetratricopeptide repeat 57 90 5.3E-7 T 28-03-2018 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 Gene3D G3DSA:1.25.40.10 98 151 4.0E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 Gene3D G3DSA:1.25.40.10 152 192 4.1E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS11000 37ab2d0ffd0dd5312429a6322fbf5fe4 224 Gene3D G3DSA:1.20.58.280 193 222 0.001 T 28-03-2018 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 Gene3D G3DSA:3.40.50.720 1 179 9.1E-35 T 28-03-2018 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 465 4.1E-134 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 4 466 3.1E-221 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 Gene3D G3DSA:1.10.1040.10 180 433 1.9E-112 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 PIRSF PIRSF000109 1 468 3.3E-241 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 SMART SM01350 178 466 7.7E-218 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 SUPERFAMILY SSF51735 3 171 1.9E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 6.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 355 377 6.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 118 143 6.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 3 26 6.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 65 94 6.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 248 275 6.9E-87 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 252 264 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 172 2.9E-51 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 SUPERFAMILY SSF48179 176 467 9.36E-130 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR44_RS10475 fd0bb59ea43f54312de4868a1cabad51 468 Gene3D G3DSA:1.20.5.320 434 467 3.9E-20 T 28-03-2018 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 Gene3D G3DSA:3.50.50.60 1 415 2.4E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 416 1.2E-8 T 28-03-2018 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 166 1.2E-8 T 28-03-2018 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.2E-8 T 28-03-2018 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 Pfam PF03486 HI0933-like protein 3 410 7.7E-153 T 28-03-2018 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 4 410 1.8E-143 T 28-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 2.0E-8 T 28-03-2018 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 366 388 2.0E-8 T 28-03-2018 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.0E-8 T 28-03-2018 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 SUPERFAMILY SSF51905 2 192 4.0E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 SUPERFAMILY SSF51905 356 413 4.0E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11655 47359c1e8252b1ea751de4e855d7d00f 416 SUPERFAMILY SSF160996 191 359 2.62E-46 T 28-03-2018 CWR44_RS10855 ba6342811c10a6a5281ab7ca5bf877dc 324 Gene3D G3DSA:3.40.50.300 3 132 1.8E-15 T 28-03-2018 CWR44_RS10855 ba6342811c10a6a5281ab7ca5bf877dc 324 SUPERFAMILY SSF52540 4 201 6.37E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10855 ba6342811c10a6a5281ab7ca5bf877dc 324 SUPERFAMILY SSF48019 205 324 2.38E-21 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CWR44_RS10855 ba6342811c10a6a5281ab7ca5bf877dc 324 Pfam PF06144 DNA polymerase III, delta subunit 8 182 3.5E-40 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CWR44_RS10855 ba6342811c10a6a5281ab7ca5bf877dc 324 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 4 324 8.8E-81 T 28-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CWR44_RS10855 ba6342811c10a6a5281ab7ca5bf877dc 324 Gene3D G3DSA:1.20.272.10 214 324 1.9E-28 T 28-03-2018 CWR44_RS10855 ba6342811c10a6a5281ab7ca5bf877dc 324 Gene3D G3DSA:1.10.8.60 135 213 4.4E-17 T 28-03-2018 CWR44_RS06120 547e3acd9d1834b4cb257a2fb01dbc26 308 Gene3D G3DSA:2.40.50.100 63 227 0.005 T 28-03-2018 CWR44_RS06120 547e3acd9d1834b4cb257a2fb01dbc26 308 Pfam PF13437 HlyD family secretion protein 142 233 1.5E-5 T 28-03-2018 CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 Gene3D G3DSA:3.20.20.80 1 470 5.9E-143 T 28-03-2018 CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 SUPERFAMILY SSF51445 2 467 3.98E-156 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 Pfam PF00232 Glycosyl hydrolase family 1 3 468 2.5E-170 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 371 379 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 PRINTS PR00131 Glycosyl hydrolase family 1 signature 438 450 2.7E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 2.7E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 2.7E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 PRINTS PR00131 Glycosyl hydrolase family 1 signature 371 379 2.7E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 431 2.7E-24 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 TIGRFAM TIGR01233 lacG: 6-phospho-beta-galactosidase 3 469 6.3E-258 T 28-03-2018 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85 CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 Hamap MF_01574 6-phospho-beta-galactosidase [lacG]. 1 470 67.377 T 28-03-2018 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85 CWR44_RS00585 a65801c2b97eba37896d156d6bee0e11 470 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CWR44_RS00730 3d9d89c37cec06bb5e71fa5ef24fd6bb 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.723 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z CWR44_RS00730 3d9d89c37cec06bb5e71fa5ef24fd6bb 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 8.2E-25 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00730 3d9d89c37cec06bb5e71fa5ef24fd6bb 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00730 3d9d89c37cec06bb5e71fa5ef24fd6bb 61 SUPERFAMILY SSF57716 3 61 2.57E-22 T 28-03-2018 CWR44_RS00730 3d9d89c37cec06bb5e71fa5ef24fd6bb 61 Gene3D G3DSA:4.10.830.10 1 61 7.4E-22 T 28-03-2018 CWR44_RS12765 021918d34217c76114a76e60c3e38937 570 Gene3D G3DSA:3.90.350.10 260 498 2.1E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS12765 021918d34217c76114a76e60c3e38937 570 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS12765 021918d34217c76114a76e60c3e38937 570 Pfam PF01609 Transposase DDE domain 264 515 9.0E-38 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 Pfam PF00873 AcrB/AcrD/AcrF family 5 1049 2.1E-195 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 Gene3D G3DSA:1.20.1640.10 836 1052 3.8E-41 T 28-03-2018 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 Gene3D G3DSA:1.20.1640.10 308 535 1.9E-47 T 28-03-2018 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 Gene3D G3DSA:3.30.70.1430 603 743 0.097 T 28-03-2018 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 PRINTS PR00702 Acriflavin resistance protein family signature 481 504 3.1E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 PRINTS PR00702 Acriflavin resistance protein family signature 506 529 3.1E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 3.1E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 PRINTS PR00702 Acriflavin resistance protein family signature 370 393 3.1E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 PRINTS PR00702 Acriflavin resistance protein family signature 425 449 3.1E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 PRINTS PR00702 Acriflavin resistance protein family signature 397 418 3.1E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 3.1E-43 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 SUPERFAMILY SSF82693 309 351 4.55E-12 T 28-03-2018 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 SUPERFAMILY SSF82693 135 181 4.55E-12 T 28-03-2018 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 SUPERFAMILY SSF82714 747 831 1.01E-9 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 Gene3D G3DSA:3.30.70.1430 42 141 4.8E-18 T 28-03-2018 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 SUPERFAMILY SSF82693 42 133 2.2E-13 T 28-03-2018 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 SUPERFAMILY SSF82866 331 533 9.81E-43 T 28-03-2018 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 SUPERFAMILY SSF82866 830 1051 2.88E-46 T 28-03-2018 CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 Gene3D G3DSA:3.30.2090.10 180 307 2.5E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 Gene3D G3DSA:3.30.2090.10 746 833 2.1E-14 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CWR44_RS00845 9e967b70218be1978d2c22f0f069c24b 1060 SUPERFAMILY SSF82714 182 246 3.14E-6 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CWR44_RS13100 0fb8950599b9efdba85c65036238ad40 664 Pfam PF07670 Nucleoside recognition 511 635 1.7E-29 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR44_RS13100 0fb8950599b9efdba85c65036238ad40 664 Pfam PF07670 Nucleoside recognition 350 443 3.3E-14 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR44_RS13100 0fb8950599b9efdba85c65036238ad40 664 Pfam PF07664 Ferrous iron transport protein B C terminus 454 506 1.1E-19 T 28-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CWR44_RS13100 0fb8950599b9efdba85c65036238ad40 664 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 631 3.9E-190 T 28-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CWR44_RS13100 0fb8950599b9efdba85c65036238ad40 664 Gene3D G3DSA:3.40.50.300 4 314 8.1E-31 T 28-03-2018 CWR44_RS13100 0fb8950599b9efdba85c65036238ad40 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 51 66 6.9E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS13100 0fb8950599b9efdba85c65036238ad40 664 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 6.9E-5 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS13100 0fb8950599b9efdba85c65036238ad40 664 Pfam PF02421 Ferrous iron transport protein B 5 155 1.0E-56 T 28-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CWR44_RS13100 0fb8950599b9efdba85c65036238ad40 664 SUPERFAMILY SSF52540 6 169 7.91E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00910 738e66407aea282fbdb93a636245b0c8 160 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 160 33.497 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CWR44_RS00910 738e66407aea282fbdb93a636245b0c8 160 SUPERFAMILY SSF55040 11 158 1.05E-56 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CWR44_RS00910 738e66407aea282fbdb93a636245b0c8 160 Gene3D G3DSA:3.30.70.640 2 160 3.2E-66 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CWR44_RS00910 738e66407aea282fbdb93a636245b0c8 160 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 155 1.1E-60 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CWR44_RS00910 738e66407aea282fbdb93a636245b0c8 160 Pfam PF01967 MoaC family 15 153 2.1E-52 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CWR44_RS05405 027e561d986f3da39932bb36ab9c6e94 121 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 118 5.7E-40 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWR44_RS05405 027e561d986f3da39932bb36ab9c6e94 121 TIGRFAM TIGR00526 folB_dom: FolB domain 3 121 3.4E-32 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWR44_RS05405 027e561d986f3da39932bb36ab9c6e94 121 Gene3D G3DSA:3.30.1130.10 2 120 2.3E-33 T 28-03-2018 CWR44_RS05405 027e561d986f3da39932bb36ab9c6e94 121 SUPERFAMILY SSF55620 1 120 5.78E-43 T 28-03-2018 CWR44_RS05405 027e561d986f3da39932bb36ab9c6e94 121 Pfam PF02152 Dihydroneopterin aldolase 5 116 4.1E-33 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWR44_RS05405 027e561d986f3da39932bb36ab9c6e94 121 SMART SM00905 5 118 1.1E-51 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CWR44_RS12820 c84e52ce6cbd924e07e1a52bb3e91644 333 Gene3D G3DSA:3.60.40.10 82 332 4.3E-31 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR44_RS12820 c84e52ce6cbd924e07e1a52bb3e91644 333 SUPERFAMILY SSF81606 129 330 1.2E-12 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR44_RS12820 c84e52ce6cbd924e07e1a52bb3e91644 333 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 143 331 2.0E-46 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR44_RS12820 c84e52ce6cbd924e07e1a52bb3e91644 333 SUPERFAMILY SSF101215 2 81 7.85E-27 T 28-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 CWR44_RS12820 c84e52ce6cbd924e07e1a52bb3e91644 333 Gene3D G3DSA:1.10.1240.30 2 80 3.8E-16 T 28-03-2018 IPR017944 KaiA/RbsU helical domain GO:0006468 CWR44_RS12820 c84e52ce6cbd924e07e1a52bb3e91644 333 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 7 79 4.5E-19 T 28-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 CWR44_RS12820 c84e52ce6cbd924e07e1a52bb3e91644 333 SMART SM00332 91 329 4.1E-6 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR44_RS12820 c84e52ce6cbd924e07e1a52bb3e91644 333 ProDom PD685490 RSBU REGULATOR SIGMA REGULATION FACTOR B PHOSPHATASE SIGMAB INDIRECT SIGMA-B 1 87 2.0E-43 T 28-03-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 CWR44_RS12820 c84e52ce6cbd924e07e1a52bb3e91644 333 SMART SM00331 116 331 7.4E-74 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR44_RS10710 36ba65633c458836fb823ba4a9657653 296 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 174 181 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CWR44_RS10710 36ba65633c458836fb823ba4a9657653 296 SMART SM00518 2 284 1.8E-124 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CWR44_RS10710 36ba65633c458836fb823ba4a9657653 296 Hamap MF_00152 Probable endonuclease 4 [nfo]. 1 284 43.178 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CWR44_RS10710 36ba65633c458836fb823ba4a9657653 296 SUPERFAMILY SSF51658 1 294 6.55E-103 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWR44_RS10710 36ba65633c458836fb823ba4a9657653 296 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 68 76 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CWR44_RS10710 36ba65633c458836fb823ba4a9657653 296 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 2 281 1.0E-98 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CWR44_RS10710 36ba65633c458836fb823ba4a9657653 296 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 212 228 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CWR44_RS10710 36ba65633c458836fb823ba4a9657653 296 Gene3D G3DSA:3.20.20.150 1 296 4.8E-60 T 28-03-2018 CWR44_RS10710 36ba65633c458836fb823ba4a9657653 296 Pfam PF01261 Xylose isomerase-like TIM barrel 20 236 1.1E-39 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 Pfam PF08245 Mur ligase middle domain 111 294 5.5E-44 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 SUPERFAMILY SSF63418 1 103 9.42E-23 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 Gene3D G3DSA:3.40.1190.10 96 311 2.0E-56 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 390 5.2E-13 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 SUPERFAMILY SSF53623 105 312 1.44E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 450 2.2E-130 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 451 32.679 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 Gene3D G3DSA:3.90.190.20 314 451 2.7E-40 T 28-03-2018 CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 Pfam PF01225 Mur ligase family, catalytic domain 25 100 7.0E-11 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 Gene3D G3DSA:3.40.1390.10 2 95 1.8E-22 T 28-03-2018 CWR44_RS12865 9e62b06619058a71da037ffd621f9b81 451 SUPERFAMILY SSF53244 316 450 1.59E-36 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR44_RS01950 7d46450217377105fbc1bc80ee724596 371 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 4 348 3.6E-80 T 28-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CWR44_RS01950 7d46450217377105fbc1bc80ee724596 371 Gene3D G3DSA:3.30.9.10 181 308 1.6E-26 T 28-03-2018 CWR44_RS01950 7d46450217377105fbc1bc80ee724596 371 SUPERFAMILY SSF54373 221 308 6.28E-17 T 28-03-2018 CWR44_RS01950 7d46450217377105fbc1bc80ee724596 371 Gene3D G3DSA:3.50.50.60 1 180 4.1E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01950 7d46450217377105fbc1bc80ee724596 371 SUPERFAMILY SSF51905 309 365 9.06E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01950 7d46450217377105fbc1bc80ee724596 371 SUPERFAMILY SSF51905 1 221 9.06E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01950 7d46450217377105fbc1bc80ee724596 371 Pfam PF01266 FAD dependent oxidoreductase 3 346 4.5E-66 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 310 1.4E-114 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 Gene3D G3DSA:3.30.420.40 5 147 1.8E-43 T 28-03-2018 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 Gene3D G3DSA:3.30.420.40 148 293 5.8E-19 T 28-03-2018 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 SUPERFAMILY SSF53067 105 311 4.91E-45 T 28-03-2018 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 SUPERFAMILY SSF53067 6 126 4.4E-32 T 28-03-2018 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 317 2.5E-135 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 Pfam PF00814 Glycoprotease family 28 310 2.2E-105 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 335 62.608 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 2.2E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 2.2E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 2.2E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 2.2E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 2.2E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 2.2E-49 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12700 8e60d2a2f1cb4e03f2fd741bf823dd78 342 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CWR44_RS11270 163162e7f9c7179730ca81e0ad85e75e 175 Gene3D G3DSA:3.30.110.10 83 175 3.7E-36 T 28-03-2018 CWR44_RS11270 163162e7f9c7179730ca81e0ad85e75e 175 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 4 174 30.584 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWR44_RS11270 163162e7f9c7179730ca81e0ad85e75e 175 SUPERFAMILY SSF54364 9 82 8.76E-29 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWR44_RS11270 163162e7f9c7179730ca81e0ad85e75e 175 Gene3D G3DSA:3.10.20.80 6 82 1.3E-30 T 28-03-2018 CWR44_RS11270 163162e7f9c7179730ca81e0ad85e75e 175 ProSitePatterns PS00938 Initiation factor 3 signature. 62 75 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CWR44_RS11270 163162e7f9c7179730ca81e0ad85e75e 175 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 11 79 1.4E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWR44_RS11270 163162e7f9c7179730ca81e0ad85e75e 175 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 11 172 1.2E-70 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CWR44_RS11270 163162e7f9c7179730ca81e0ad85e75e 175 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 87 171 2.4E-39 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CWR44_RS11270 163162e7f9c7179730ca81e0ad85e75e 175 SUPERFAMILY SSF55200 86 175 1.28E-33 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CWR44_RS12330 c8238d677203e62d497d839654d82ad6 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 6.0E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR44_RS12330 c8238d677203e62d497d839654d82ad6 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 88 104 6.0E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR44_RS12330 c8238d677203e62d497d839654d82ad6 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 66 79 6.0E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR44_RS12330 c8238d677203e62d497d839654d82ad6 250 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 6.0E-20 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR44_RS12330 c8238d677203e62d497d839654d82ad6 250 Pfam PF00557 Metallopeptidase family M24 12 240 2.2E-47 T 28-03-2018 IPR000994 Peptidase M24 CWR44_RS12330 c8238d677203e62d497d839654d82ad6 250 Gene3D G3DSA:3.90.230.10 1 250 1.8E-69 T 28-03-2018 CWR44_RS12330 c8238d677203e62d497d839654d82ad6 250 Hamap MF_01974 Methionine aminopeptidase [map]. 1 249 36.573 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR44_RS12330 c8238d677203e62d497d839654d82ad6 250 SUPERFAMILY SSF55920 2 248 3.53E-73 T 28-03-2018 IPR000994 Peptidase M24 CWR44_RS12330 c8238d677203e62d497d839654d82ad6 250 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 1 248 8.0E-85 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 SUPERFAMILY SSF55021 650 728 1.19E-7 T 28-03-2018 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 Gene3D G3DSA:3.30.70.260 649 729 3.6E-9 T 28-03-2018 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 Pfam PF13291 ACT domain 649 726 8.8E-18 T 28-03-2018 IPR002912 ACT domain CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 SUPERFAMILY SSF81301 199 371 2.29E-64 T 28-03-2018 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 Gene3D G3DSA:3.30.460.10 197 330 4.4E-43 T 28-03-2018 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 SUPERFAMILY SSF109604 10 195 2.86E-72 T 28-03-2018 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 Pfam PF13328 HD domain 34 180 1.4E-45 T 28-03-2018 IPR003607 HD/PDEase domain CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 2.5E-40 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 SUPERFAMILY SSF81271 382 454 1.96E-22 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 SMART SM00954 240 350 6.6E-69 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 32 725 2.0E-239 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 Pfam PF02824 TGS domain 395 454 2.8E-20 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 SMART SM00471 46 158 7.8E-7 T 28-03-2018 IPR003607 HD/PDEase domain CWR44_RS11070 e4690d89ea5c7400213bd48f79dedc4b 729 Gene3D G3DSA:3.10.20.30 389 462 8.3E-21 T 28-03-2018 IPR012675 Beta-grasp domain CWR44_RS07985 ecb802bc4c9a2249ca837b77433e897e 370 Gene3D G3DSA:3.40.50.970 3 363 3.3E-86 T 28-03-2018 CWR44_RS07985 ecb802bc4c9a2249ca837b77433e897e 370 Pfam PF00676 Dehydrogenase E1 component 53 342 4.1E-102 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CWR44_RS07985 ecb802bc4c9a2249ca837b77433e897e 370 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 23 363 3.7E-146 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CWR44_RS07985 ecb802bc4c9a2249ca837b77433e897e 370 SUPERFAMILY SSF52518 18 365 1.34E-103 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS07440 388f09011ac4a2bff4f203a0812540d6 608 Gene3D G3DSA:3.40.50.1110 407 604 1.1E-17 T 28-03-2018 CWR44_RS07440 388f09011ac4a2bff4f203a0812540d6 608 Pfam PF01757 Acyltransferase family 19 350 6.1E-29 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CWR44_RS07440 388f09011ac4a2bff4f203a0812540d6 608 SUPERFAMILY SSF52266 448 602 4.12E-17 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWR44_RS09760 f5a0cf782bd11558da89d395d6459a97 1011 Gene3D G3DSA:3.40.50.300 1 225 8.7E-20 T 28-03-2018 CWR44_RS09760 f5a0cf782bd11558da89d395d6459a97 1011 Pfam PF13558 Putative exonuclease SbcCD, C subunit 894 969 8.5E-14 T 28-03-2018 CWR44_RS09760 f5a0cf782bd11558da89d395d6459a97 1011 Gene3D G3DSA:1.10.287.510 455 584 3.4E-7 T 28-03-2018 CWR44_RS09760 f5a0cf782bd11558da89d395d6459a97 1011 Pfam PF13476 AAA domain 5 215 3.7E-23 T 28-03-2018 CWR44_RS09760 f5a0cf782bd11558da89d395d6459a97 1011 Gene3D G3DSA:3.40.50.300 729 1007 1.2E-13 T 28-03-2018 CWR44_RS09760 f5a0cf782bd11558da89d395d6459a97 1011 SUPERFAMILY SSF52540 132 226 2.09E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS09760 f5a0cf782bd11558da89d395d6459a97 1011 SUPERFAMILY SSF52540 903 996 2.09E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS09760 f5a0cf782bd11558da89d395d6459a97 1011 SUPERFAMILY SSF52540 24 98 2.09E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05820 013acc38bce4e0b80c01c279c5144057 538 SUPERFAMILY SSF48208 239 452 1.81E-12 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CWR44_RS05820 013acc38bce4e0b80c01c279c5144057 538 Gene3D G3DSA:1.50.10.10 192 410 1.7E-11 T 28-03-2018 CWR44_RS08170 6ed9962ed877b6542153eaf88f611af1 352 SUPERFAMILY SSF55681 95 344 6.81E-80 T 28-03-2018 CWR44_RS08170 6ed9962ed877b6542153eaf88f611af1 352 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 23 90 1.6E-24 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CWR44_RS08170 6ed9962ed877b6542153eaf88f611af1 352 Gene3D G3DSA:3.30.930.10 10 347 1.1E-95 T 28-03-2018 CWR44_RS08170 6ed9962ed877b6542153eaf88f611af1 352 SUPERFAMILY SSF46589 15 102 2.2E-22 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWR44_RS08170 6ed9962ed877b6542153eaf88f611af1 352 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 11 343 48.774 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CWR44_RS08170 6ed9962ed877b6542153eaf88f611af1 352 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 42 344 6.2E-114 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CWR44_RS08170 6ed9962ed877b6542153eaf88f611af1 352 Pfam PF01409 tRNA synthetases class II core domain (F) 95 343 2.5E-108 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CWR44_RS09210 3ca16f5f087b9de028404d203bb63fa4 127 Pfam PF05105 Bacteriophage holin family 13 120 2.6E-26 T 28-03-2018 IPR006480 Bacteriophage holin family CWR44_RS09210 3ca16f5f087b9de028404d203bb63fa4 127 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 10 126 3.2E-24 T 28-03-2018 IPR006480 Bacteriophage holin family CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 Pfam PF13091 PLD-like domain 335 458 1.7E-28 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 Pfam PF13091 PLD-like domain 146 274 6.8E-13 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 Gene3D G3DSA:3.30.870.10 118 313 1.5E-34 T 28-03-2018 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 Gene3D G3DSA:3.30.870.10 314 472 2.2E-33 T 28-03-2018 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 PIRSF PIRSF000850 304 395 11.0 T 28-03-2018 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 PIRSF PIRSF000850 105 271 0.0022 T 28-03-2018 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 PIRSF PIRSF000850 385 492 0.048 T 28-03-2018 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 Pfam PF13396 Phospholipase_D-nuclease N-terminal 23 67 5.9E-12 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 SMART SM00155 228 255 6.1E-6 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 SMART SM00155 406 433 3.3E-8 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 Hamap MF_01916 Cardiolipin synthase. 18 493 42.175 T 28-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 11 493 6.4E-225 T 28-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 SUPERFAMILY SSF56024 83 322 2.79E-49 T 28-03-2018 CWR44_RS09280 40fde466ac0d4dde32f96debdb920f1f 493 SUPERFAMILY SSF56024 279 478 1.7E-56 T 28-03-2018 CWR44_RS02550 be865f972615782cf1a5f12c53c07f0a 754 SMART SM00342 170 253 9.4E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS02550 be865f972615782cf1a5f12c53c07f0a 754 Gene3D G3DSA:1.10.10.60 149 207 7.0E-10 T 28-03-2018 CWR44_RS02550 be865f972615782cf1a5f12c53c07f0a 754 SUPERFAMILY SSF51445 318 620 2.53E-14 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWR44_RS02550 be865f972615782cf1a5f12c53c07f0a 754 SUPERFAMILY SSF51011 609 753 1.19E-28 T 28-03-2018 CWR44_RS02550 be865f972615782cf1a5f12c53c07f0a 754 SUPERFAMILY SSF46689 206 257 3.58E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS02550 be865f972615782cf1a5f12c53c07f0a 754 Gene3D G3DSA:1.10.10.60 209 273 1.1E-10 T 28-03-2018 CWR44_RS02550 be865f972615782cf1a5f12c53c07f0a 754 Gene3D G3DSA:2.60.40.1500 607 754 6.0E-22 T 28-03-2018 CWR44_RS02550 be865f972615782cf1a5f12c53c07f0a 754 Gene3D G3DSA:2.60.120.280 17 138 8.7E-8 T 28-03-2018 CWR44_RS02550 be865f972615782cf1a5f12c53c07f0a 754 Pfam PF12833 Helix-turn-helix domain 177 254 3.5E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS00965 4ad5be4ddf8c8f737484c7e10a07aba2 381 SUPERFAMILY SSF47203 235 380 4.35E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CWR44_RS00965 4ad5be4ddf8c8f737484c7e10a07aba2 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 99 6.9E-7 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CWR44_RS00965 4ad5be4ddf8c8f737484c7e10a07aba2 381 PIRSF PIRSF016578 4 109 2.0E-8 T 28-03-2018 CWR44_RS00965 4ad5be4ddf8c8f737484c7e10a07aba2 381 PIRSF PIRSF016578 138 380 1.3E-23 T 28-03-2018 CWR44_RS00965 4ad5be4ddf8c8f737484c7e10a07aba2 381 Gene3D G3DSA:1.10.540.10 9 123 2.7E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CWR44_RS00965 4ad5be4ddf8c8f737484c7e10a07aba2 381 Gene3D G3DSA:2.40.110.10 124 228 2.4E-20 T 28-03-2018 CWR44_RS00965 4ad5be4ddf8c8f737484c7e10a07aba2 381 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 245 359 3.1E-12 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CWR44_RS00965 4ad5be4ddf8c8f737484c7e10a07aba2 381 Gene3D G3DSA:1.20.140.10 231 377 1.2E-17 T 28-03-2018 CWR44_RS00965 4ad5be4ddf8c8f737484c7e10a07aba2 381 SUPERFAMILY SSF56645 22 226 4.45E-43 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CWR44_RS00965 4ad5be4ddf8c8f737484c7e10a07aba2 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 218 4.5E-12 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CWR44_RS06585 6665d8579c7c766a77f34bf2c0560a64 381 SUPERFAMILY SSF56322 10 378 5.1E-95 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CWR44_RS06585 6665d8579c7c766a77f34bf2c0560a64 381 Pfam PF00425 chorismate binding enzyme 117 374 1.4E-79 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CWR44_RS06585 6665d8579c7c766a77f34bf2c0560a64 381 PRINTS PR00095 Anthranilate synthase component I signature 236 249 9.2E-6 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS06585 6665d8579c7c766a77f34bf2c0560a64 381 PRINTS PR00095 Anthranilate synthase component I signature 222 235 9.2E-6 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS06585 6665d8579c7c766a77f34bf2c0560a64 381 PRINTS PR00095 Anthranilate synthase component I signature 316 330 9.2E-6 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS06585 6665d8579c7c766a77f34bf2c0560a64 381 Gene3D G3DSA:3.60.120.10 37 379 1.9E-94 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CWR44_RS10445 148f687d9a0f7a44fa5106813f4b9472 271 SUPERFAMILY SSF51735 1 159 2.63E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10445 148f687d9a0f7a44fa5106813f4b9472 271 SUPERFAMILY SSF48179 160 268 1.11E-27 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR44_RS10445 148f687d9a0f7a44fa5106813f4b9472 271 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 265 6.9E-83 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR44_RS10445 148f687d9a0f7a44fa5106813f4b9472 271 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 265 21.649 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR44_RS10445 148f687d9a0f7a44fa5106813f4b9472 271 Gene3D G3DSA:1.10.3730.10 159 270 8.1E-29 T 28-03-2018 CWR44_RS10445 148f687d9a0f7a44fa5106813f4b9472 271 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 161 265 1.1E-27 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CWR44_RS10445 148f687d9a0f7a44fa5106813f4b9472 271 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 98 5.6E-17 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CWR44_RS10445 148f687d9a0f7a44fa5106813f4b9472 271 PIRSF PIRSF000193 1 268 1.3E-88 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CWR44_RS10445 148f687d9a0f7a44fa5106813f4b9472 271 Gene3D G3DSA:3.40.50.720 1 158 3.5E-20 T 28-03-2018 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 SMART SM00387 34 178 7.0E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 Pfam PF01751 Toprim domain 427 537 1.9E-17 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 7 642 50.347 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 573 633 4.1E-29 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR01159 DNA gyrase subunit B signature 366 380 6.4E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR01159 DNA gyrase subunit B signature 478 487 6.4E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR01159 DNA gyrase subunit B signature 380 400 6.4E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR01159 DNA gyrase subunit B signature 597 609 6.4E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR01159 DNA gyrase subunit B signature 225 247 6.4E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR01159 DNA gyrase subunit B signature 316 332 6.4E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR01159 DNA gyrase subunit B signature 184 199 6.4E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR01159 DNA gyrase subunit B signature 199 212 6.4E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR01159 DNA gyrase subunit B signature 613 629 6.4E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR01159 DNA gyrase subunit B signature 9 19 6.4E-55 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 Pfam PF00204 DNA gyrase B 226 396 1.8E-58 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 SUPERFAMILY SSF55874 8 217 7.2E-66 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 ProSitePatterns PS00177 DNA topoisomerase II signature. 430 438 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 Gene3D G3DSA:3.30.565.10 21 225 6.4E-74 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 177 6.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 SUPERFAMILY SSF56719 402 639 7.06E-85 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 SMART SM00433 38 637 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 SUPERFAMILY SSF54211 226 397 7.78E-54 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR00418 DNA topoisomerase II family signature 532 544 4.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR00418 DNA topoisomerase II family signature 512 529 4.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR00418 DNA topoisomerase II family signature 115 129 4.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR00418 DNA topoisomerase II family signature 73 86 4.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR00418 DNA topoisomerase II family signature 272 285 4.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR00418 DNA topoisomerase II family signature 576 592 4.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR00418 DNA topoisomerase II family signature 428 442 4.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR00418 DNA topoisomerase II family signature 494 510 4.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 PRINTS PR00418 DNA topoisomerase II family signature 38 53 4.5E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 6 645 0.0 T 28-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 Gene3D G3DSA:3.30.230.10 226 398 9.6E-56 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS09795 7c2cb34338c3260e3b56073f921895ff 666 Gene3D G3DSA:3.40.50.670 407 640 1.5E-91 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 Pfam PF00005 ABC transporter 28 64 2.1E-8 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 Pfam PF00005 ABC transporter 99 131 6.2E-6 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 Pfam PF00005 ABC transporter 314 438 1.1E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 Gene3D G3DSA:3.40.50.300 11 281 7.6E-38 T 28-03-2018 CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 SMART SM00091 156 226 0.0024 T 28-03-2018 IPR000014 PAS domain CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 SMART SM00382 323 483 1.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 SMART SM00382 30 177 8.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 Gene3D G3DSA:3.40.50.300 288 487 9.4E-34 T 28-03-2018 CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 SUPERFAMILY SSF52540 279 484 1.65E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 SUPERFAMILY SSF52540 4 196 3.3E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS13130 4d04e430dec118f56b7a4723a711d943 488 ProSitePatterns PS00211 ABC transporters family signature. 103 117 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS09475 1549bfd9d3c975bd8b2d38170ac03b42 249 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 148 215 2.0E-11 T 28-03-2018 IPR006343 DnaD domain CWR44_RS09475 1549bfd9d3c975bd8b2d38170ac03b42 249 SUPERFAMILY SSF158499 152 209 1.57E-6 T 28-03-2018 IPR006343 DnaD domain CWR44_RS09475 1549bfd9d3c975bd8b2d38170ac03b42 249 Pfam PF07261 Replication initiation and membrane attachment 154 216 2.7E-10 T 28-03-2018 IPR006343 DnaD domain CWR44_RS09475 1549bfd9d3c975bd8b2d38170ac03b42 249 Gene3D G3DSA:1.10.10.630 139 215 8.8E-12 T 28-03-2018 IPR034829 DnaD-like domain CWR44_RS09475 1549bfd9d3c975bd8b2d38170ac03b42 249 Pfam PF13730 Helix-turn-helix domain 25 77 1.4E-9 T 28-03-2018 CWR44_RS09475 1549bfd9d3c975bd8b2d38170ac03b42 249 Gene3D G3DSA:1.10.10.10 15 89 0.03 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10295 741b92bc26b8396243898bdae27034c3 354 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 348 34.155 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWR44_RS10295 741b92bc26b8396243898bdae27034c3 354 Gene3D G3DSA:3.40.50.1970 1 166 2.4E-38 T 28-03-2018 CWR44_RS10295 741b92bc26b8396243898bdae27034c3 354 Pfam PF01761 3-dehydroquinate synthase 62 316 3.0E-83 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWR44_RS10295 741b92bc26b8396243898bdae27034c3 354 Gene3D G3DSA:1.20.1090.10 167 354 1.4E-41 T 28-03-2018 CWR44_RS10295 741b92bc26b8396243898bdae27034c3 354 SUPERFAMILY SSF56796 1 346 3.01E-87 T 28-03-2018 CWR44_RS10295 741b92bc26b8396243898bdae27034c3 354 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 12 340 6.6E-105 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWR44_RS10295 741b92bc26b8396243898bdae27034c3 354 PIRSF PIRSF001455 1 350 4.5E-103 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CWR44_RS02455 97617c358eca0871b102f657d31bc167 248 Gene3D G3DSA:3.40.50.1000 96 239 1.1E-25 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS02455 97617c358eca0871b102f657d31bc167 248 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 206 2.1E-25 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS02455 97617c358eca0871b102f657d31bc167 248 Gene3D G3DSA:3.40.50.1000 2 30 0.29 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS02455 97617c358eca0871b102f657d31bc167 248 Gene3D G3DSA:1.10.150.240 31 95 9.9E-11 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CWR44_RS02455 97617c358eca0871b102f657d31bc167 248 SUPERFAMILY SSF56784 4 217 7.27E-41 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS02455 97617c358eca0871b102f657d31bc167 248 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 110 200 4.4E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS02455 97617c358eca0871b102f657d31bc167 248 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 81 206 1.2E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS03990 20e36a8768e11a331ded426b4d500cf8 113 Gene3D G3DSA:1.10.10.10 1 110 7.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03990 20e36a8768e11a331ded426b4d500cf8 113 SMART SM00418 35 113 4.9E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03990 20e36a8768e11a331ded426b4d500cf8 113 SUPERFAMILY SSF46785 16 104 1.67E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03990 20e36a8768e11a331ded426b4d500cf8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 4.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03990 20e36a8768e11a331ded426b4d500cf8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 4.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03990 20e36a8768e11a331ded426b4d500cf8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 4.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03990 20e36a8768e11a331ded426b4d500cf8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 4.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03990 20e36a8768e11a331ded426b4d500cf8 113 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CWR44_RS03990 20e36a8768e11a331ded426b4d500cf8 113 Pfam PF01022 Bacterial regulatory protein, arsR family 41 84 7.7E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS05355 8f170110782f6fe2f00485b29571ea15 396 SUPERFAMILY SSF101386 232 334 1.25E-20 T 28-03-2018 CWR44_RS05355 8f170110782f6fe2f00485b29571ea15 396 Gene3D G3DSA:3.40.1010.10 3 120 3.9E-12 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS05355 8f170110782f6fe2f00485b29571ea15 396 Gene3D G3DSA:1.10.287.1080 233 352 4.1E-34 T 28-03-2018 CWR44_RS05355 8f170110782f6fe2f00485b29571ea15 396 PIRSF PIRSF002845 1 388 4.9E-153 T 28-03-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted CWR44_RS05355 8f170110782f6fe2f00485b29571ea15 396 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 206 5.6E-16 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS05355 8f170110782f6fe2f00485b29571ea15 396 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 257 330 6.2E-25 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CWR44_RS05355 8f170110782f6fe2f00485b29571ea15 396 SUPERFAMILY SSF53790 4 265 1.12E-30 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS07460 c49510d2521add5a41ef22fcf9b4d3a0 414 SUPERFAMILY SSF53901 215 412 4.25E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS07460 c49510d2521add5a41ef22fcf9b4d3a0 414 SMART SM00825 Beta-ketoacyl synthase 7 414 1.4E-16 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CWR44_RS07460 c49510d2521add5a41ef22fcf9b4d3a0 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 369 1.7E-37 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CWR44_RS07460 c49510d2521add5a41ef22fcf9b4d3a0 414 PIRSF PIRSF000447 2 414 8.5E-185 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CWR44_RS07460 c49510d2521add5a41ef22fcf9b4d3a0 414 SUPERFAMILY SSF53901 4 252 1.61E-77 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS07460 c49510d2521add5a41ef22fcf9b4d3a0 414 Gene3D G3DSA:3.40.47.10 263 414 4.3E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS07460 c49510d2521add5a41ef22fcf9b4d3a0 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CWR44_RS07460 c49510d2521add5a41ef22fcf9b4d3a0 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 247 5.1E-62 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CWR44_RS07460 c49510d2521add5a41ef22fcf9b4d3a0 414 Gene3D G3DSA:3.40.47.10 7 260 2.2E-79 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS07460 c49510d2521add5a41ef22fcf9b4d3a0 414 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 5 410 1.1E-193 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CWR44_RS03795 4f7e3dac4d3a78867cd3eb49a3f10101 143 SUPERFAMILY SSF55620 30 135 5.56E-23 T 28-03-2018 CWR44_RS03795 4f7e3dac4d3a78867cd3eb49a3f10101 143 Gene3D G3DSA:3.30.479.10 2 140 1.7E-22 T 28-03-2018 CWR44_RS03795 4f7e3dac4d3a78867cd3eb49a3f10101 143 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 25 137 1.0E-17 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 PIRSF PIRSF000429 1 383 8.1E-125 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 Pfam PF02803 Thiolase, C-terminal domain 261 380 6.8E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 SUPERFAMILY SSF53901 1 255 7.02E-77 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 ProSitePatterns PS00099 Thiolases active site. 363 376 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 379 1.1E-135 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 Gene3D G3DSA:3.40.47.10 255 379 1.1E-28 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 Gene3D G3DSA:3.40.47.10 1 254 1.2E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 Pfam PF00108 Thiolase, N-terminal domain 4 252 3.2E-88 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CWR44_RS02200 381a3b1743ecc6ca33b2bb2be1a19748 383 SUPERFAMILY SSF53901 261 379 6.64E-37 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS06355 a48fd452d05ded88a5a3a4ec409160e4 272 Gene3D G3DSA:3.10.350.10 22 82 1.7E-17 T 28-03-2018 CWR44_RS06355 a48fd452d05ded88a5a3a4ec409160e4 272 SUPERFAMILY SSF54001 154 271 1.57E-20 T 28-03-2018 CWR44_RS06355 a48fd452d05ded88a5a3a4ec409160e4 272 SUPERFAMILY SSF54106 90 133 6.41E-12 T 28-03-2018 IPR018392 LysM domain CWR44_RS06355 a48fd452d05ded88a5a3a4ec409160e4 272 Gene3D G3DSA:3.10.350.10 83 151 5.5E-18 T 28-03-2018 CWR44_RS06355 a48fd452d05ded88a5a3a4ec409160e4 272 SMART SM00257 28 71 5.4E-17 T 28-03-2018 IPR018392 LysM domain CWR44_RS06355 a48fd452d05ded88a5a3a4ec409160e4 272 SMART SM00257 90 133 1.4E-17 T 28-03-2018 IPR018392 LysM domain CWR44_RS06355 a48fd452d05ded88a5a3a4ec409160e4 272 Pfam PF01476 LysM domain 91 133 8.0E-16 T 28-03-2018 IPR018392 LysM domain CWR44_RS06355 a48fd452d05ded88a5a3a4ec409160e4 272 Pfam PF01476 LysM domain 29 70 7.6E-16 T 28-03-2018 IPR018392 LysM domain CWR44_RS06355 a48fd452d05ded88a5a3a4ec409160e4 272 SUPERFAMILY SSF54106 27 70 1.1E-12 T 28-03-2018 IPR018392 LysM domain CWR44_RS06355 a48fd452d05ded88a5a3a4ec409160e4 272 Pfam PF05257 CHAP domain 166 247 5.7E-13 T 28-03-2018 IPR007921 CHAP domain CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 SMART SM00448 2 115 1.4E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 Gene3D G3DSA:3.40.50.2300 1 141 2.6E-30 T 28-03-2018 CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 3.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 3.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 3.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 Gene3D G3DSA:1.10.10.10 142 200 3.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 SUPERFAMILY SSF52172 1 129 5.83E-29 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 SMART SM00421 137 194 7.5E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 191 3.0E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 SUPERFAMILY SSF46894 129 200 1.5E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS09300 05fc4b3e7f6812e435b04c41097d7d0d 200 Pfam PF00072 Response regulator receiver domain 4 115 2.8E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 Pfam PF13769 Virulence factor 107 186 7.3E-27 T 28-03-2018 IPR025989 Virulence factor domain CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 5 84 6.5E-19 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 Pfam PF13646 HEAT repeats 235 314 3.2E-11 T 28-03-2018 CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 SMART SM00932 4 91 5.4E-19 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 SUPERFAMILY SSF48371 231 367 2.18E-24 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 Gene3D G3DSA:1.25.40.70 290 354 1.0E-6 T 28-03-2018 CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 Gene3D G3DSA:1.25.40.70 181 289 1.1E-11 T 28-03-2018 CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 SMART SM00567 E-Z type HEAT repeats 307 336 53.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 SMART SM00567 E-Z type HEAT repeats 276 305 0.4 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 SMART SM00567 E-Z type HEAT repeats 245 274 62.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 SUPERFAMILY SSF110836 1 84 2.22E-24 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CWR44_RS10140 4fedfbfd20a744f7b74e17fa2bc17a4e 370 Gene3D G3DSA:3.30.1370.70 2 86 7.9E-18 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CWR44_RS09025 ec0a77b12c704ba9b03e2dfea542edd9 240 Pfam PF07261 Replication initiation and membrane attachment 154 214 1.0E-8 T 28-03-2018 IPR006343 DnaD domain CWR44_RS09025 ec0a77b12c704ba9b03e2dfea542edd9 240 SUPERFAMILY SSF158499 143 208 6.15E-9 T 28-03-2018 IPR006343 DnaD domain CWR44_RS09025 ec0a77b12c704ba9b03e2dfea542edd9 240 Gene3D G3DSA:1.10.10.630 137 213 1.1E-10 T 28-03-2018 IPR034829 DnaD-like domain CWR44_RS09025 ec0a77b12c704ba9b03e2dfea542edd9 240 Gene3D G3DSA:1.10.10.60 17 97 4.7E-4 T 28-03-2018 CWR44_RS09025 ec0a77b12c704ba9b03e2dfea542edd9 240 Pfam PF13730 Helix-turn-helix domain 19 73 1.9E-15 T 28-03-2018 CWR44_RS09025 ec0a77b12c704ba9b03e2dfea542edd9 240 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 143 213 8.0E-11 T 28-03-2018 IPR006343 DnaD domain CWR44_RS09885 380c02d5bc1888abfc453f16977936e9 243 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 1 243 27.551 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWR44_RS09885 380c02d5bc1888abfc453f16977936e9 243 SUPERFAMILY SSF51366 3 238 9.04E-73 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR44_RS09885 380c02d5bc1888abfc453f16977936e9 243 Gene3D G3DSA:3.20.20.70 1 243 2.9E-62 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS09885 380c02d5bc1888abfc453f16977936e9 243 Pfam PF00290 Tryptophan synthase alpha chain 3 237 6.3E-77 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWR44_RS09885 380c02d5bc1888abfc453f16977936e9 243 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 15 239 2.4E-64 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWR44_RS09885 380c02d5bc1888abfc453f16977936e9 243 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 30 43 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 Gene3D G3DSA:1.20.120.140 204 311 3.2E-32 T 28-03-2018 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 SMART SM00963 2 87 1.4E-32 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 2.5E-22 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 SMART SM00962 101 297 3.6E-116 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 SMART SM00382 100 247 7.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 Gene3D G3DSA:3.40.50.300 94 203 3.8E-17 T 28-03-2018 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 Gene3D G3DSA:1.20.120.140 1 92 5.3E-30 T 28-03-2018 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 2.7E-190 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 2.2E-77 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 449 35.229 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 SUPERFAMILY SSF47446 328 430 9.97E-39 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 Gene3D G3DSA:1.10.260.30 328 432 6.0E-40 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 Pfam PF02978 Signal peptide binding domain 328 427 1.6E-34 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CWR44_RS08595 829774c31f31cca72537afe1e313b85b 456 SUPERFAMILY SSF52540 43 355 8.76E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00140 612d746d5976ff85ff03ec62939a1e1f 133 Gene3D G3DSA:1.20.5.440 90 131 3.2E-10 T 28-03-2018 CWR44_RS00140 612d746d5976ff85ff03ec62939a1e1f 133 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 22.456 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00140 612d746d5976ff85ff03ec62939a1e1f 133 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 131 1.7E-11 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00140 612d746d5976ff85ff03ec62939a1e1f 133 SUPERFAMILY SSF46604 88 132 6.28E-5 T 28-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00140 612d746d5976ff85ff03ec62939a1e1f 133 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 89 1.0E-41 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00140 612d746d5976ff85ff03ec62939a1e1f 133 Gene3D G3DSA:2.60.15.10 2 89 1.1E-25 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00140 612d746d5976ff85ff03ec62939a1e1f 133 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 1.2E-24 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00140 612d746d5976ff85ff03ec62939a1e1f 133 SUPERFAMILY SSF51344 3 85 1.01E-22 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00140 612d746d5976ff85ff03ec62939a1e1f 133 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 131 2.4E-34 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS05080 439437ab7c703f452d4a8115f62a92d3 285 Pfam PF01734 Patatin-like phospholipase 9 198 1.8E-13 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CWR44_RS05080 439437ab7c703f452d4a8115f62a92d3 285 SUPERFAMILY SSF52151 5 271 7.06E-32 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWR44_RS05080 439437ab7c703f452d4a8115f62a92d3 285 Gene3D G3DSA:3.40.1090.10 2 262 1.9E-29 T 28-03-2018 CWR44_RS08560 bb575591174f77475d63860a6b2a7339 309 PIRSF PIRSF000446 1 305 6.9E-100 T 28-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CWR44_RS08560 bb575591174f77475d63860a6b2a7339 309 Gene3D G3DSA:3.30.70.250 141 186 3.0E-20 T 28-03-2018 CWR44_RS08560 bb575591174f77475d63860a6b2a7339 309 SUPERFAMILY SSF55048 127 195 4.32E-15 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CWR44_RS08560 bb575591174f77475d63860a6b2a7339 309 Gene3D G3DSA:3.40.366.10 3 140 4.5E-34 T 28-03-2018 CWR44_RS08560 bb575591174f77475d63860a6b2a7339 309 Gene3D G3DSA:3.40.366.10 187 307 2.1E-24 T 28-03-2018 CWR44_RS08560 bb575591174f77475d63860a6b2a7339 309 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 9.8E-98 T 28-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CWR44_RS08560 bb575591174f77475d63860a6b2a7339 309 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 304 4.5E-27 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CWR44_RS08560 bb575591174f77475d63860a6b2a7339 309 SUPERFAMILY SSF52151 4 119 9.68E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWR44_RS08560 bb575591174f77475d63860a6b2a7339 309 SUPERFAMILY SSF52151 188 304 9.68E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWR44_RS08560 bb575591174f77475d63860a6b2a7339 309 Pfam PF00698 Acyl transferase domain 7 284 3.6E-33 T 28-03-2018 IPR014043 Acyl transferase CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 2.7E-34 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 1.6E-60 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 Gene3D G3DSA:2.40.30.10 300 393 4.3E-33 T 28-03-2018 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 3.4E-18 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 SUPERFAMILY SSF50447 203 301 1.47E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 Gene3D G3DSA:3.40.50.300 75 192 3.3E-31 T 28-03-2018 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 5.8E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 5.8E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 5.8E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 5.8E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 5.8E-25 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 9.9E-234 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 59.953 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 146 3.2E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 SUPERFAMILY SSF50465 302 394 2.65E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 Gene3D G3DSA:3.40.50.300 1 74 1.5E-11 T 28-03-2018 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 Gene3D G3DSA:2.40.30.10 193 298 2.1E-32 T 28-03-2018 CWR44_RS05665 ce09229b3aed8f78cc378142e90a6a16 394 SUPERFAMILY SSF52540 6 219 2.2E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06325 3c4c9d57bda891e95d2c1653f9cf0dbf 224 SUPERFAMILY SSF52172 1 117 2.99E-33 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS06325 3c4c9d57bda891e95d2c1653f9cf0dbf 224 SUPERFAMILY SSF46894 126 221 6.8E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS06325 3c4c9d57bda891e95d2c1653f9cf0dbf 224 Gene3D G3DSA:1.10.10.10 123 224 4.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06325 3c4c9d57bda891e95d2c1653f9cf0dbf 224 SMART SM00862 147 222 5.9E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS06325 3c4c9d57bda891e95d2c1653f9cf0dbf 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 221 4.3E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS06325 3c4c9d57bda891e95d2c1653f9cf0dbf 224 Pfam PF00072 Response regulator receiver domain 3 111 2.1E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS06325 3c4c9d57bda891e95d2c1653f9cf0dbf 224 SMART SM00448 1 111 3.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS06325 3c4c9d57bda891e95d2c1653f9cf0dbf 224 Gene3D G3DSA:3.40.50.2300 1 122 7.7E-29 T 28-03-2018 CWR44_RS11190 8de07d67f820b4958c8b8128daad230b 184 SUPERFAMILY SSF48150 2 182 4.39E-66 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CWR44_RS11190 8de07d67f820b4958c8b8128daad230b 184 Gene3D G3DSA:1.10.340.30 1 182 2.7E-64 T 28-03-2018 CWR44_RS11190 8de07d67f820b4958c8b8128daad230b 184 Pfam PF03352 Methyladenine glycosylase 8 180 1.5E-63 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CWR44_RS07160 943c6824ba9e079c89135b2d391189bc 465 SUPERFAMILY SSF101960 32 462 6.28E-143 T 28-03-2018 CWR44_RS07160 943c6824ba9e079c89135b2d391189bc 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 1.6E-232 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CWR44_RS07160 943c6824ba9e079c89135b2d391189bc 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 4.8E-75 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CWR44_RS02910 6daef22360f3cd524afcc43fc2829351 290 Gene3D G3DSA:3.40.190.10 92 177 8.9E-20 T 28-03-2018 CWR44_RS02910 6daef22360f3cd524afcc43fc2829351 290 SUPERFAMILY SSF46785 1 110 5.92E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02910 6daef22360f3cd524afcc43fc2829351 290 Pfam PF03466 LysR substrate binding domain 87 286 1.6E-35 T 28-03-2018 IPR005119 LysR, substrate-binding CWR44_RS02910 6daef22360f3cd524afcc43fc2829351 290 Gene3D G3DSA:1.10.10.10 1 91 3.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02910 6daef22360f3cd524afcc43fc2829351 290 SUPERFAMILY SSF53850 89 288 1.78E-34 T 28-03-2018 CWR44_RS02910 6daef22360f3cd524afcc43fc2829351 290 Gene3D G3DSA:3.40.190.10 178 264 7.2E-13 T 28-03-2018 CWR44_RS02910 6daef22360f3cd524afcc43fc2829351 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.1E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS12250 0d9cc7d5c1816ee75947e2084a775f5e 172 SUPERFAMILY SSF52317 3 170 2.44E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS12250 0d9cc7d5c1816ee75947e2084a775f5e 172 Pfam PF01965 DJ-1/PfpI family 3 169 1.7E-51 T 28-03-2018 IPR002818 DJ-1/PfpI CWR44_RS12250 0d9cc7d5c1816ee75947e2084a775f5e 172 Gene3D G3DSA:3.40.50.880 1 172 4.9E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS12250 0d9cc7d5c1816ee75947e2084a775f5e 172 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 171 1.7E-46 T 28-03-2018 IPR006286 Peptidase C56, PfpI CWR44_RS05860 ec6a33d3eff68f77135e83e81c34c7ae 461 ProSitePatterns PS00455 Putative AMP-binding domain signature. 133 144 - T 28-03-2018 IPR020845 AMP-binding, conserved site CWR44_RS05860 ec6a33d3eff68f77135e83e81c34c7ae 461 Gene3D G3DSA:3.40.50.980 3 136 5.8E-9 T 28-03-2018 CWR44_RS05860 ec6a33d3eff68f77135e83e81c34c7ae 461 Gene3D G3DSA:3.30.300.30 357 460 6.3E-22 T 28-03-2018 CWR44_RS05860 ec6a33d3eff68f77135e83e81c34c7ae 461 Gene3D G3DSA:3.40.50.980 137 285 1.8E-19 T 28-03-2018 CWR44_RS05860 ec6a33d3eff68f77135e83e81c34c7ae 461 Pfam PF13193 AMP-binding enzyme C-terminal domain 372 444 3.3E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CWR44_RS05860 ec6a33d3eff68f77135e83e81c34c7ae 461 Pfam PF00501 AMP-binding enzyme 11 362 1.8E-30 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CWR44_RS05860 ec6a33d3eff68f77135e83e81c34c7ae 461 SUPERFAMILY SSF56801 5 456 2.22E-68 T 28-03-2018 CWR44_RS05860 ec6a33d3eff68f77135e83e81c34c7ae 461 Gene3D G3DSA:2.30.38.10 286 355 0.0014 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 ProSitePatterns PS01047 Heavy-metal-associated domain. 78 107 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 496 502 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 Gene3D G3DSA:3.30.70.100 3 71 1.3E-18 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 SUPERFAMILY SSF81653 302 392 4.58E-26 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 Gene3D G3DSA:3.40.1110.10 509 613 3.4E-31 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 Pfam PF00122 E1-E2 ATPase 292 473 2.3E-57 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 SUPERFAMILY SSF55008 3 71 6.54E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 Gene3D G3DSA:3.30.70.100 72 159 1.1E-23 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 205 791 1.0E-189 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 224 790 7.8E-206 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 342 356 6.6E-29 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 635 645 6.6E-29 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 711 723 6.6E-29 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 613 624 6.6E-29 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 688 707 6.6E-29 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 494 508 6.6E-29 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 39 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 Gene3D G3DSA:3.40.50.1000 614 752 2.0E-43 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 Pfam PF00702 haloacid dehalogenase-like hydrolase 490 702 8.0E-49 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 Gene3D G3DSA:1.20.1110.10 257 508 2.5E-53 T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 PRINTS PR00941 Cadmium-transporting ATPase signature 377 391 1.8E-5 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 PRINTS PR00941 Cadmium-transporting ATPase signature 87 108 1.8E-5 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 PRINTS PR00941 Cadmium-transporting ATPase signature 358 374 1.8E-5 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 SUPERFAMILY SSF55008 73 143 6.81E-22 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 Pfam PF00403 Heavy-metal-associated domain 8 68 1.8E-13 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 Pfam PF00403 Heavy-metal-associated domain 76 136 1.3E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 8 70 7.7E-9 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 SUPERFAMILY SSF81665 259 295 5.49E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 SUPERFAMILY SSF81665 393 488 5.49E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 SUPERFAMILY SSF81665 737 767 5.49E-14 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 ProSitePatterns PS01229 Hypothetical cof family signature 2. 688 710 - T 28-03-2018 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 264 777 1.4E-101 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 SUPERFAMILY SSF56784 546 788 5.15E-64 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS02260 f23e48996e0f55148e7369139e0aa9f2 795 SUPERFAMILY SSF56784 492 512 5.15E-64 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS11620 4401a550cd204ea50a052c13c2d39674 282 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 3 278 5.4E-143 T 28-03-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 CWR44_RS11620 4401a550cd204ea50a052c13c2d39674 282 Gene3D G3DSA:3.30.470.10 1 131 2.5E-29 T 28-03-2018 CWR44_RS11620 4401a550cd204ea50a052c13c2d39674 282 Pfam PF01063 Amino-transferase class IV 30 252 7.7E-40 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR44_RS11620 4401a550cd204ea50a052c13c2d39674 282 ProSitePatterns PS00770 Aminotransferases class-IV signature. 178 207 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR44_RS11620 4401a550cd204ea50a052c13c2d39674 282 Gene3D G3DSA:3.20.10.10 132 281 8.4E-37 T 28-03-2018 CWR44_RS11620 4401a550cd204ea50a052c13c2d39674 282 SUPERFAMILY SSF56752 3 276 1.7E-79 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR44_RS09270 b48797de015b85e4e813f5dc38693f82 341 Gene3D G3DSA:3.40.640.10 1 254 3.7E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS09270 b48797de015b85e4e813f5dc38693f82 341 SUPERFAMILY SSF53383 1 341 4.44E-79 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS09270 b48797de015b85e4e813f5dc38693f82 341 Gene3D G3DSA:3.90.1150.10 255 341 2.0E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS09270 b48797de015b85e4e813f5dc38693f82 341 Pfam PF01212 Beta-eliminating lyase 28 270 3.5E-29 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CWR44_RS01830 52da96b15e78caca879e0f1412717b31 358 Pfam PF05343 M42 glutamyl aminopeptidase 45 340 4.2E-113 T 28-03-2018 IPR008007 Peptidase M42 CWR44_RS01830 52da96b15e78caca879e0f1412717b31 358 PIRSF PIRSF001123 1 358 4.8E-146 T 28-03-2018 IPR008007 Peptidase M42 CWR44_RS01830 52da96b15e78caca879e0f1412717b31 358 SUPERFAMILY SSF101821 70 180 8.24E-34 T 28-03-2018 CWR44_RS01830 52da96b15e78caca879e0f1412717b31 358 Gene3D G3DSA:2.40.30.40 69 161 3.6E-34 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CWR44_RS01830 52da96b15e78caca879e0f1412717b31 358 Gene3D G3DSA:3.40.630.10 172 356 1.1E-46 T 28-03-2018 CWR44_RS01830 52da96b15e78caca879e0f1412717b31 358 SUPERFAMILY SSF53187 4 80 2.13E-68 T 28-03-2018 CWR44_RS01830 52da96b15e78caca879e0f1412717b31 358 SUPERFAMILY SSF53187 172 355 2.13E-68 T 28-03-2018 CWR44_RS03640 fcfbd4b436bdd96270634421c27e04b7 100 SUPERFAMILY SSF52794 1 98 7.85E-29 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR44_RS03640 fcfbd4b436bdd96270634421c27e04b7 100 Gene3D G3DSA:3.40.50.2300 1 98 2.2E-28 T 28-03-2018 CWR44_RS03640 fcfbd4b436bdd96270634421c27e04b7 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 94 6.1E-15 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR44_RS01275 7c33d7d2a0278dc0952e81608b7c1c10 402 Pfam PF07690 Major Facilitator Superfamily 21 359 8.0E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS01275 7c33d7d2a0278dc0952e81608b7c1c10 402 SUPERFAMILY SSF103473 6 390 3.53E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01275 7c33d7d2a0278dc0952e81608b7c1c10 402 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 13 389 5.7E-88 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CWR44_RS01275 7c33d7d2a0278dc0952e81608b7c1c10 402 Gene3D G3DSA:1.20.1250.20 202 395 1.3E-16 T 28-03-2018 CWR44_RS01275 7c33d7d2a0278dc0952e81608b7c1c10 402 Gene3D G3DSA:1.20.1250.20 4 201 1.7E-34 T 28-03-2018 CWR44_RS01275 7c33d7d2a0278dc0952e81608b7c1c10 402 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 84 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CWR44_RS01275 7c33d7d2a0278dc0952e81608b7c1c10 402 PRINTS PR01035 Tetracycline resistance protein signature 108 129 5.0E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR44_RS01275 7c33d7d2a0278dc0952e81608b7c1c10 402 PRINTS PR01035 Tetracycline resistance protein signature 356 379 5.0E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR44_RS01275 7c33d7d2a0278dc0952e81608b7c1c10 402 PRINTS PR01035 Tetracycline resistance protein signature 24 40 5.0E-7 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR44_RS12210 8be969e442364fdb36516b106e575685 180 Hamap MF_01568 UPF0374 protein . 4 178 50.827 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 CWR44_RS12210 8be969e442364fdb36516b106e575685 180 PIRSF PIRSF028345 4 180 1.2E-78 T 28-03-2018 IPR016882 Uncharacterised protein family UPF0374 CWR44_RS12210 8be969e442364fdb36516b106e575685 180 Gene3D G3DSA:2.40.380.10 18 174 8.2E-33 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CWR44_RS12210 8be969e442364fdb36516b106e575685 180 Pfam PF04167 Protein of unknown function (DUF402) 63 127 2.1E-17 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CWR44_RS12210 8be969e442364fdb36516b106e575685 180 SUPERFAMILY SSF159234 7 173 8.37E-32 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 SUPERFAMILY SSF50249 1 63 2.11E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 SMART SM00278 108 127 0.24 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 SMART SM00278 73 92 0.38 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 SUPERFAMILY SSF47781 66 133 6.12E-21 T 28-03-2018 IPR010994 RuvA domain 2-like CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 Pfam PF07499 RuvA, C-terminal domain 156 199 5.4E-10 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 Gene3D G3DSA:2.40.50.140 1 56 2.6E-19 T 28-03-2018 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 2 199 8.3E-51 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 200 29.074 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 Gene3D G3DSA:1.10.150.20 81 142 1.3E-16 T 28-03-2018 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 Pfam PF01330 RuvA N terminal domain 1 62 6.4E-19 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 Gene3D G3DSA:1.10.150.280 57 80 0.0014 T 28-03-2018 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 SUPERFAMILY SSF46929 153 199 1.96E-7 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 Gene3D G3DSA:1.10.8.10 143 200 2.4E-7 T 28-03-2018 CWR44_RS11110 528e69003b70b087df4fc38db10766e9 201 Pfam PF14520 Helix-hairpin-helix domain 72 129 2.3E-14 T 28-03-2018 CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 Gene3D G3DSA:1.20.1640.10 204 416 1.9E-29 T 28-03-2018 CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 PRINTS PR01755 Bacterial translocase SecF protein signature 480 495 4.9E-26 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 PRINTS PR01755 Bacterial translocase SecF protein signature 674 689 4.9E-26 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 PRINTS PR01755 Bacterial translocase SecF protein signature 638 656 4.9E-26 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 PRINTS PR01755 Bacterial translocase SecF protein signature 590 604 4.9E-26 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 482 726 2.7E-67 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 SUPERFAMILY SSF82866 221 415 5.49E-38 T 28-03-2018 CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 425 31.161 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 Pfam PF02355 Protein export membrane protein 549 735 2.9E-62 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 Pfam PF02355 Protein export membrane protein 243 414 5.6E-14 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 188 404 1.8E-51 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 517 723 2.3E-48 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 453 737 24.939 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 Pfam PF07549 SecD/SecF GG Motif 32 49 0.086 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 Pfam PF07549 SecD/SecF GG Motif 476 499 2.9E-4 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 34 411 9.3E-97 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 SUPERFAMILY SSF82866 546 739 6.8E-36 T 28-03-2018 CWR44_RS11085 c2a46dbc35226314142813a75b3d461f 761 Gene3D G3DSA:1.20.1640.10 527 746 2.6E-32 T 28-03-2018 CWR44_RS08035 c5712d81811b5f7c1d58df2caf70d7f1 400 SUPERFAMILY SSF90123 21 149 3.81E-5 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR44_RS08035 c5712d81811b5f7c1d58df2caf70d7f1 400 Gene3D G3DSA:1.20.1070.10 1 370 8.6E-7 T 28-03-2018 CWR44_RS08035 c5712d81811b5f7c1d58df2caf70d7f1 400 Pfam PF13273 Protein of unknown function (DUF4064) 14 126 1.8E-18 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 363 46.178 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 SUPERFAMILY SSF103025 4 280 1.52E-94 T 28-03-2018 CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 Gene3D G3DSA:3.30.1360.120 5 134 2.2E-35 T 28-03-2018 CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 265 357 1.4E-23 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 SUPERFAMILY SSF101790 273 358 5.72E-22 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 359 1.1E-133 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 Gene3D G3DSA:3.30.1360.120 135 235 7.1E-26 T 28-03-2018 CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 Gene3D G3DSA:4.10.1250.10 236 279 8.6E-11 T 28-03-2018 CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 257 4.4E-93 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 Gene3D G3DSA:2.40.30.110 281 363 3.6E-20 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CWR44_RS10605 016f522509eea61c465acaaf4163a758 363 PIRSF PIRSF006487 1 362 5.4E-96 T 28-03-2018 CWR44_RS02410 6dbe27e67ed8d3dfb8583f633b41e2ff 234 Gene3D G3DSA:3.30.1330.80 2 94 6.3E-30 T 28-03-2018 CWR44_RS02410 6dbe27e67ed8d3dfb8583f633b41e2ff 234 SUPERFAMILY SSF117856 4 234 1.48E-76 T 28-03-2018 CWR44_RS02410 6dbe27e67ed8d3dfb8583f633b41e2ff 234 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 4 234 5.4E-74 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CWR44_RS02410 6dbe27e67ed8d3dfb8583f633b41e2ff 234 Pfam PF03306 Alpha-acetolactate decarboxylase 5 222 6.6E-76 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CWR44_RS02410 6dbe27e67ed8d3dfb8583f633b41e2ff 234 PIRSF PIRSF001332 1 234 4.0E-91 T 28-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CWR44_RS02410 6dbe27e67ed8d3dfb8583f633b41e2ff 234 Gene3D G3DSA:3.30.1330.80 95 198 1.9E-41 T 28-03-2018 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 SUPERFAMILY SSF54980 408 503 1.49E-26 T 28-03-2018 IPR035647 EF-G domain III/V-like CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 SUPERFAMILY SSF54980 301 379 6.47E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 Gene3D G3DSA:3.30.70.240 398 558 4.6E-28 T 28-03-2018 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 Gene3D G3DSA:2.40.30.10 197 296 7.0E-27 T 28-03-2018 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 PRINTS PR00315 GTP-binding elongation factor signature 15 28 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 PRINTS PR00315 GTP-binding elongation factor signature 83 93 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 PRINTS PR00315 GTP-binding elongation factor signature 135 144 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 PRINTS PR00315 GTP-binding elongation factor signature 99 110 4.0E-14 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 Gene3D G3DSA:3.30.70.870 297 376 6.7E-27 T 28-03-2018 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 Gene3D G3DSA:3.40.50.300 8 194 1.0E-37 T 28-03-2018 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 SMART SM00838 407 495 2.5E-5 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 Pfam PF00679 Elongation factor G C-terminus 408 495 5.6E-24 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 3.1E-48 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 Pfam PF00009 Elongation factor Tu GTP binding domain 11 190 3.1E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 Pfam PF03144 Elongation factor Tu domain 2 214 284 1.9E-11 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 302.711 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 185 9.5E-20 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR44_RS10845 50d31b6e1e5cd4d7769048f41bf76607 607 SUPERFAMILY SSF52540 4 235 4.25E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS01600 b81325067e16b7b9eae6e74160b19048 228 PIRSF PIRSF000709 2 218 9.0E-8 T 28-03-2018 CWR44_RS01600 b81325067e16b7b9eae6e74160b19048 228 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 228 6.1E-102 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CWR44_RS01600 b81325067e16b7b9eae6e74160b19048 228 Gene3D G3DSA:3.40.50.1240 1 228 6.3E-60 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWR44_RS01600 b81325067e16b7b9eae6e74160b19048 228 SUPERFAMILY SSF53254 1 223 5.68E-71 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWR44_RS01600 b81325067e16b7b9eae6e74160b19048 228 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 42.592 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CWR44_RS01600 b81325067e16b7b9eae6e74160b19048 228 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CWR44_RS01600 b81325067e16b7b9eae6e74160b19048 228 SMART SM00855 3 189 1.2E-22 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWR44_RS01600 b81325067e16b7b9eae6e74160b19048 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 127 6.6E-29 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 6.0E-73 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 37.652 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 Gene3D G3DSA:3.40.190.10 105 198 6.4E-33 T 28-03-2018 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 SUPERFAMILY SSF54782 220 307 2.48E-20 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 292 1.9E-17 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 2.1E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 2.1E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 2.1E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 2.1E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 2.1E-48 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 292 8.6E-105 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 Gene3D G3DSA:3.40.190.10 1 104 1.3E-39 T 28-03-2018 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 Gene3D G3DSA:3.30.160.40 219 304 2.8E-17 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 SUPERFAMILY SSF53850 2 216 2.82E-76 T 28-03-2018 CWR44_RS11215 2f31d5339d853fce9b0c4ae36a3a07a3 310 PIRSF PIRSF001438 1 310 5.2E-113 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS05365 49fbf05857194dd7bea85c57c662f29d 131 Pfam PF04977 Septum formation initiator 41 118 9.8E-17 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CWR44_RS06860 522d6d43d843a495c210afe54025a48d 479 Gene3D G3DSA:1.25.40.10 17 129 5.2E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS06860 522d6d43d843a495c210afe54025a48d 479 SUPERFAMILY SSF48452 17 103 4.93E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS06860 522d6d43d843a495c210afe54025a48d 479 Pfam PF13181 Tetratricopeptide repeat 27 48 0.0079 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS06860 522d6d43d843a495c210afe54025a48d 479 Gene3D G3DSA:1.25.40.10 233 316 0.0072 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS06860 522d6d43d843a495c210afe54025a48d 479 SUPERFAMILY SSF48452 151 267 4.3E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS06860 522d6d43d843a495c210afe54025a48d 479 SMART SM00028 15 48 0.031 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS06860 522d6d43d843a495c210afe54025a48d 479 SMART SM00028 176 209 21.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS06860 522d6d43d843a495c210afe54025a48d 479 SMART SM00028 279 312 210.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS06860 522d6d43d843a495c210afe54025a48d 479 Gene3D G3DSA:1.25.40.10 143 232 1.2E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 Gene3D G3DSA:3.50.30.20 2 142 8.3E-55 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 358 48.871 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 SMART SM01097 3 133 1.4E-77 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00097 Anthranilate synthase component II signature 243 254 3.5E-6 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00097 Anthranilate synthase component II signature 216 225 3.5E-6 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00097 Anthranilate synthase component II signature 329 342 3.5E-6 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 130 6.7E-50 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 SUPERFAMILY SSF52317 146 358 5.87E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 Gene3D G3DSA:3.40.50.880 143 359 2.3E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 260 277 4.7E-36 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 213 227 4.7E-36 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 243 259 4.7E-36 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 285 296 4.7E-36 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 174 188 4.7E-36 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 6 355 2.0E-146 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 Pfam PF00117 Glutamine amidotransferase class-I 176 352 1.5E-49 T 28-03-2018 IPR017926 Glutamine amidotransferase CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 243 254 1.8E-11 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 216 225 1.8E-11 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 329 342 1.8E-11 T 28-03-2018 CWR44_RS08420 3d73863b78ba5aa489d180c5aed06653 366 SUPERFAMILY SSF52021 4 146 5.49E-54 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS12545 4fe5e77f91fb5caaf79ac1a88419f1d2 126 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 9.2E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS12545 4fe5e77f91fb5caaf79ac1a88419f1d2 126 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 9.2E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS12545 4fe5e77f91fb5caaf79ac1a88419f1d2 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 8.1E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS12545 4fe5e77f91fb5caaf79ac1a88419f1d2 126 SMART SM00345 17 76 2.0E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS12545 4fe5e77f91fb5caaf79ac1a88419f1d2 126 Gene3D G3DSA:1.10.10.10 1 90 6.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12545 4fe5e77f91fb5caaf79ac1a88419f1d2 126 SUPERFAMILY SSF46785 6 80 2.12E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10705 a81f90f788519e44c6941b40495e1e29 258 Pfam PF00005 ABC transporter 21 171 4.6E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS10705 a81f90f788519e44c6941b40495e1e29 258 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS10705 a81f90f788519e44c6941b40495e1e29 258 Gene3D G3DSA:3.40.50.300 1 242 5.9E-64 T 28-03-2018 CWR44_RS10705 a81f90f788519e44c6941b40495e1e29 258 SMART SM00382 30 225 8.0E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS10705 a81f90f788519e44c6941b40495e1e29 258 SUPERFAMILY SSF52540 3 231 7.64E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS12015 15ffa73e2b55583243baa03d0d85dd60 484 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 279 375 1.2E-26 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWR44_RS12015 15ffa73e2b55583243baa03d0d85dd60 484 SMART SM00062 41 262 7.6E-56 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR44_RS12015 15ffa73e2b55583243baa03d0d85dd60 484 SUPERFAMILY SSF161098 279 469 4.32E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS12015 15ffa73e2b55583243baa03d0d85dd60 484 Gene3D G3DSA:1.10.3720.10 272 483 7.5E-42 T 28-03-2018 CWR44_RS12015 15ffa73e2b55583243baa03d0d85dd60 484 Gene3D G3DSA:3.40.190.10 145 225 1.4E-17 T 28-03-2018 CWR44_RS12015 15ffa73e2b55583243baa03d0d85dd60 484 SUPERFAMILY SSF53850 1 259 3.72E-63 T 28-03-2018 CWR44_RS12015 15ffa73e2b55583243baa03d0d85dd60 484 Gene3D G3DSA:3.40.190.10 31 144 2.1E-36 T 28-03-2018 CWR44_RS12015 15ffa73e2b55583243baa03d0d85dd60 484 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 298 481 2.3E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS12015 15ffa73e2b55583243baa03d0d85dd60 484 SMART SM00079 41 259 5.8E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CWR44_RS12015 15ffa73e2b55583243baa03d0d85dd60 484 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 257 8.8E-55 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR44_RS11030 53c869747f319b9e5e61e82fb9abb51c 140 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 124 3.0E-32 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CWR44_RS11030 53c869747f319b9e5e61e82fb9abb51c 140 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 28-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CWR44_RS11030 53c869747f319b9e5e61e82fb9abb51c 140 SUPERFAMILY SSF46785 2 126 3.91E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11030 53c869747f319b9e5e61e82fb9abb51c 140 Pfam PF02082 Transcriptional regulator 1 82 3.5E-26 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CWR44_RS11030 53c869747f319b9e5e61e82fb9abb51c 140 Gene3D G3DSA:1.10.10.10 1 140 4.8E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11330 69c8a169b4e26a953362ee80b2be3fdf 422 Gene3D G3DSA:3.40.718.10 1 422 3.8E-138 T 28-03-2018 CWR44_RS11330 69c8a169b4e26a953362ee80b2be3fdf 422 SMART SM01329 20 417 9.8E-186 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWR44_RS11330 69c8a169b4e26a953362ee80b2be3fdf 422 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 21 416 8.6E-123 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWR44_RS11330 69c8a169b4e26a953362ee80b2be3fdf 422 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 421 4.9E-212 T 28-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CWR44_RS11330 69c8a169b4e26a953362ee80b2be3fdf 422 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 306 325 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CWR44_RS11330 69c8a169b4e26a953362ee80b2be3fdf 422 SUPERFAMILY SSF53659 4 421 3.07E-141 T 28-03-2018 CWR44_RS01710 d78970e815ab1a118e81ae979c709259 584 Pfam PF06580 Histidine kinase 378 457 1.6E-24 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CWR44_RS01710 d78970e815ab1a118e81ae979c709259 584 SUPERFAMILY SSF55874 469 576 2.23E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01710 d78970e815ab1a118e81ae979c709259 584 Gene3D G3DSA:3.30.565.10 394 578 5.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01710 d78970e815ab1a118e81ae979c709259 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 577 2.6E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01710 d78970e815ab1a118e81ae979c709259 584 SMART SM00387 472 579 1.4E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01710 d78970e815ab1a118e81ae979c709259 584 SMART SM00065 237 373 0.0041 T 28-03-2018 IPR003018 GAF domain GO:0005515 CWR44_RS01710 d78970e815ab1a118e81ae979c709259 584 Pfam PF07694 5TMR of 5TMR-LYT 26 207 2.3E-48 T 28-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CWR44_RS02140 5e543552337725cbfb18a9850bb6fb6e 110 Gene3D G3DSA:3.40.30.10 1 105 6.6E-14 T 28-03-2018 CWR44_RS02140 5e543552337725cbfb18a9850bb6fb6e 110 Pfam PF00085 Thioredoxin 7 87 2.7E-9 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWR44_RS02140 5e543552337725cbfb18a9850bb6fb6e 110 SUPERFAMILY SSF52833 4 100 6.33E-22 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS08430 767fd4d76dde5f9d1c8495bec9abc1c8 230 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 229 38.676 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08430 767fd4d76dde5f9d1c8495bec9abc1c8 230 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 55 68 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08430 767fd4d76dde5f9d1c8495bec9abc1c8 230 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 5 224 9.7E-61 T 28-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08430 767fd4d76dde5f9d1c8495bec9abc1c8 230 SUPERFAMILY SSF51366 2 228 3.05E-69 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR44_RS08430 767fd4d76dde5f9d1c8495bec9abc1c8 230 Gene3D G3DSA:3.20.20.70 2 229 4.2E-60 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS08430 767fd4d76dde5f9d1c8495bec9abc1c8 230 SMART SM00934 4 224 2.2E-91 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08430 767fd4d76dde5f9d1c8495bec9abc1c8 230 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 222 3.7E-47 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08650 16b1a17cdac3f0b47e90bd4e2e8d8991 409 Gene3D G3DSA:3.40.630.30 167 388 4.4E-35 T 28-03-2018 CWR44_RS08650 16b1a17cdac3f0b47e90bd4e2e8d8991 409 SUPERFAMILY SSF46589 243 306 4.6E-14 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWR44_RS08650 16b1a17cdac3f0b47e90bd4e2e8d8991 409 SUPERFAMILY SSF55729 310 408 3.35E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS08650 16b1a17cdac3f0b47e90bd4e2e8d8991 409 SUPERFAMILY SSF55729 165 243 3.35E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS08650 16b1a17cdac3f0b47e90bd4e2e8d8991 409 Pfam PF02388 FemAB family 9 408 5.6E-135 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CWR44_RS08650 16b1a17cdac3f0b47e90bd4e2e8d8991 409 Gene3D G3DSA:3.40.630.30 1 166 2.4E-27 T 28-03-2018 CWR44_RS08650 16b1a17cdac3f0b47e90bd4e2e8d8991 409 SUPERFAMILY SSF55729 1 163 1.54E-50 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS10950 55e2ee77108a882679b2f30bfec644d3 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CWR44_RS10950 55e2ee77108a882679b2f30bfec644d3 158 SUPERFAMILY SSF46557 5 79 1.03E-27 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CWR44_RS10950 55e2ee77108a882679b2f30bfec644d3 158 SUPERFAMILY SSF54534 83 157 1.44E-19 T 28-03-2018 CWR44_RS10950 55e2ee77108a882679b2f30bfec644d3 158 Gene3D G3DSA:3.10.50.30 79 158 1.3E-24 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CWR44_RS10950 55e2ee77108a882679b2f30bfec644d3 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 2.9E-55 T 28-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CWR44_RS10950 55e2ee77108a882679b2f30bfec644d3 158 PIRSF PIRSF006092 1 158 1.2E-51 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CWR44_RS10950 55e2ee77108a882679b2f30bfec644d3 158 Gene3D G3DSA:1.10.287.180 6 78 2.0E-32 T 28-03-2018 CWR44_RS10950 55e2ee77108a882679b2f30bfec644d3 158 Pfam PF03449 Transcription elongation factor, N-terminal 8 76 3.6E-32 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CWR44_RS10950 55e2ee77108a882679b2f30bfec644d3 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 158 2.1E-25 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CWR44_RS10950 55e2ee77108a882679b2f30bfec644d3 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 32.87 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CWR44_RS10110 cec903eb237a5ead6933cbe46befc10e 142 Pfam PF01641 SelR domain 6 124 3.7E-47 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS10110 cec903eb237a5ead6933cbe46befc10e 142 Gene3D G3DSA:2.170.150.20 2 141 2.4E-49 T 28-03-2018 CWR44_RS10110 cec903eb237a5ead6933cbe46befc10e 142 SUPERFAMILY SSF51316 6 139 1.46E-56 T 28-03-2018 IPR011057 Mss4-like CWR44_RS10110 cec903eb237a5ead6933cbe46befc10e 142 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 6 133 6.2E-59 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS10110 cec903eb237a5ead6933cbe46befc10e 142 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 2 125 35.025 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 337 2.9E-143 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 Gene3D G3DSA:3.40.50.970 358 532 1.7E-42 T 28-03-2018 CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 Gene3D G3DSA:3.40.50.920 538 662 1.3E-28 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 661 7.9E-280 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 SUPERFAMILY SSF52518 5 324 1.6E-109 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 ProSitePatterns PS00802 Transketolase signature 2. 466 482 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 Pfam PF02780 Transketolase, C-terminal domain 547 655 3.2E-9 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 Gene3D G3DSA:3.40.50.970 2 357 1.4E-101 T 28-03-2018 CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 Pfam PF02779 Transketolase, pyrimidine binding domain 353 523 1.5E-41 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 SMART SM00861 353 524 7.3E-61 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 SUPERFAMILY SSF52518 344 525 1.51E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS09405 06f7e629410b93a1b2de66fcac0dbc1a 662 SUPERFAMILY SSF52922 534 660 2.88E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 251 2.1E-40 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 Gene3D G3DSA:3.40.1360.10 241 365 8.3E-32 T 28-03-2018 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 SMART SM00400 34 88 1.4E-37 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 SUPERFAMILY SSF48024 463 561 1.24E-6 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 Pfam PF01807 CHC2 zinc finger 4 97 6.3E-38 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 TIGRFAM TIGR01391 dnaG: DNA primase 2 416 1.4E-148 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 Gene3D G3DSA:3.90.980.10 107 240 2.0E-41 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 Gene3D G3DSA:1.10.860.10 464 561 8.6E-10 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 SUPERFAMILY SSF56731 114 420 1.01E-94 T 28-03-2018 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 Hamap MF_00974 DNA primase [dnaG]. 2 591 28.078 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 SMART SM00493 259 330 2.1E-12 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 Gene3D G3DSA:3.90.580.10 1 100 4.5E-34 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 SUPERFAMILY SSF57783 2 96 4.76E-35 T 28-03-2018 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 Pfam PF13155 Toprim-like 262 347 1.9E-12 T 28-03-2018 CWR44_RS10735 7530be099fe632ae3da7ac3447f6c405 601 PIRSF PIRSF002811 1 601 1.8E-188 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CWR44_RS12755 c523104d22e7fb256e879e7322e00676 191 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 4 182 2.1E-66 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CWR44_RS12755 c523104d22e7fb256e879e7322e00676 191 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 3 191 39.198 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CWR44_RS12755 c523104d22e7fb256e879e7322e00676 191 Pfam PF00694 Aconitase C-terminal domain 6 124 8.9E-32 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12755 c523104d22e7fb256e879e7322e00676 191 Gene3D G3DSA:3.20.19.10 1 170 5.3E-46 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR44_RS12755 c523104d22e7fb256e879e7322e00676 191 SUPERFAMILY SSF52016 4 186 5.3E-57 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR44_RS09330 c70a5aab9254ec8b39a1018e3506932e 460 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR44_RS09330 c70a5aab9254ec8b39a1018e3506932e 460 Gene3D G3DSA:3.30.70.260 371 447 2.3E-16 T 28-03-2018 CWR44_RS09330 c70a5aab9254ec8b39a1018e3506932e 460 SUPERFAMILY SSF53633 1 290 1.44E-65 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR44_RS09330 c70a5aab9254ec8b39a1018e3506932e 460 Gene3D G3DSA:3.30.70.260 282 370 1.3E-19 T 28-03-2018 CWR44_RS09330 c70a5aab9254ec8b39a1018e3506932e 460 Gene3D G3DSA:3.40.1160.10 1 281 1.3E-50 T 28-03-2018 CWR44_RS09330 c70a5aab9254ec8b39a1018e3506932e 460 SUPERFAMILY SSF55021 373 448 1.65E-18 T 28-03-2018 CWR44_RS09330 c70a5aab9254ec8b39a1018e3506932e 460 PIRSF PIRSF000726 1 448 2.2E-80 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR44_RS09330 c70a5aab9254ec8b39a1018e3506932e 460 SUPERFAMILY SSF55021 297 369 1.37E-12 T 28-03-2018 CWR44_RS09330 c70a5aab9254ec8b39a1018e3506932e 460 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 444 8.7E-84 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR44_RS09330 c70a5aab9254ec8b39a1018e3506932e 460 Pfam PF00696 Amino acid kinase family 2 276 3.6E-39 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 Gene3D G3DSA:3.40.710.10 240 591 6.9E-70 T 28-03-2018 CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 SUPERFAMILY SSF56601 195 613 9.13E-80 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 SUPERFAMILY SSF56519 61 242 3.79E-44 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 224 3.2E-23 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 Pfam PF03793 PASTA domain 658 712 2.6E-11 T 28-03-2018 IPR005543 PASTA domain CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 Pfam PF03793 PASTA domain 601 654 6.5E-9 T 28-03-2018 IPR005543 PASTA domain CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 Gene3D G3DSA:3.90.1310.10 27 239 3.4E-38 T 28-03-2018 CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 SUPERFAMILY SSF54184 658 712 4.19E-14 T 28-03-2018 CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 SMART SM00740 596 656 3.7E-11 T 28-03-2018 IPR005543 PASTA domain CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 SMART SM00740 657 713 7.8E-9 T 28-03-2018 IPR005543 PASTA domain CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 579 4.7E-79 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR44_RS08310 2b4ba523183963ed9f142c31e1d60347 772 SUPERFAMILY SSF54184 600 655 1.11E-16 T 28-03-2018 CWR44_RS08485 254b8b07c75f323ad4524f1c571bc899 310 SUPERFAMILY SSF53328 3 202 4.97E-64 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR44_RS08485 254b8b07c75f323ad4524f1c571bc899 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 303 36.139 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CWR44_RS08485 254b8b07c75f323ad4524f1c571bc899 310 Gene3D G3DSA:3.10.25.10 206 310 4.5E-29 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR44_RS08485 254b8b07c75f323ad4524f1c571bc899 310 Gene3D G3DSA:3.40.50.170 1 205 3.3E-67 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR44_RS08485 254b8b07c75f323ad4524f1c571bc899 310 SUPERFAMILY SSF50486 204 301 2.98E-29 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CWR44_RS08485 254b8b07c75f323ad4524f1c571bc899 310 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 132 155 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR44_RS08485 254b8b07c75f323ad4524f1c571bc899 310 Pfam PF02911 Formyl transferase, C-terminal domain 203 300 2.9E-29 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR44_RS08485 254b8b07c75f323ad4524f1c571bc899 310 Pfam PF00551 Formyl transferase 3 178 4.1E-42 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CWR44_RS08485 254b8b07c75f323ad4524f1c571bc899 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 303 6.6E-109 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 SMART SM00839 183 412 2.9E-97 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 SUPERFAMILY SSF51735 181 413 1.34E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 172 194 1.2E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 340 351 1.2E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 92 106 1.2E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 214 234 1.2E-29 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 36 162 1.2E-55 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 Gene3D G3DSA:3.40.50.10860 33 167 3.7E-51 T 28-03-2018 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 PIRSF PIRSF000185 2 414 1.5E-172 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 Gene3D G3DSA:3.40.50.720 181 414 3.5E-76 T 28-03-2018 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 100 113 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 SUPERFAMILY SSF53223 5 183 3.2E-66 T 28-03-2018 CWR44_RS07360 7c2bb3e3a2830875a20241f8be50400a 414 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 181 412 5.7E-77 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CWR44_RS00660 46bf52f2b09facd0343cd3228106f39a 123 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00660 46bf52f2b09facd0343cd3228106f39a 123 TIGRFAM TIGR00059 L17: ribosomal protein bL17 2 123 1.2E-44 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00660 46bf52f2b09facd0343cd3228106f39a 123 SUPERFAMILY SSF64263 2 123 2.88E-42 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00660 46bf52f2b09facd0343cd3228106f39a 123 Gene3D G3DSA:3.90.1030.10 1 123 1.0E-46 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00660 46bf52f2b09facd0343cd3228106f39a 123 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 122 27.048 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00660 46bf52f2b09facd0343cd3228106f39a 123 Pfam PF01196 Ribosomal protein L17 16 122 1.9E-37 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00600 530d5cd7f437b364aaec03921c8f1f65 325 SUPERFAMILY SSF51569 7 322 1.35E-67 T 28-03-2018 CWR44_RS00600 530d5cd7f437b364aaec03921c8f1f65 325 SMART SM01133 21 283 8.0E-31 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWR44_RS00600 530d5cd7f437b364aaec03921c8f1f65 325 Pfam PF01791 DeoC/LacD family aldolase 21 282 1.8E-77 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWR44_RS00600 530d5cd7f437b364aaec03921c8f1f65 325 TIGRFAM TIGR01232 lacD: tagatose 1,6-diphosphate aldolase 3 325 2.7E-204 T 28-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CWR44_RS00600 530d5cd7f437b364aaec03921c8f1f65 325 Gene3D G3DSA:3.20.20.70 4 325 3.3E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS00600 530d5cd7f437b364aaec03921c8f1f65 325 Hamap MF_00734 Tagatose 1,6-diphosphate aldolase [lacD]. 1 325 209.574 T 28-03-2018 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CWR44_RS04570 83c2b33e50e8cd9ed325a325d58159c0 749 SUPERFAMILY SSF51726 387 739 1.31E-104 T 28-03-2018 CWR44_RS04570 83c2b33e50e8cd9ed325a325d58159c0 749 SUPERFAMILY SSF51726 6 366 4.06E-88 T 28-03-2018 CWR44_RS04570 83c2b33e50e8cd9ed325a325d58159c0 749 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 415 735 1.0E-136 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWR44_RS04570 83c2b33e50e8cd9ed325a325d58159c0 749 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 9 741 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWR44_RS04570 83c2b33e50e8cd9ed325a325d58159c0 749 PIRSF PIRSF000382 3 747 0.0 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWR44_RS04570 83c2b33e50e8cd9ed325a325d58159c0 749 Gene3D G3DSA:3.20.20.210 379 742 2.6E-110 T 28-03-2018 CWR44_RS04570 83c2b33e50e8cd9ed325a325d58159c0 749 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 6 309 4.3E-110 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWR44_RS04570 83c2b33e50e8cd9ed325a325d58159c0 749 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 4 742 32.244 T 28-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWR44_RS04570 83c2b33e50e8cd9ed325a325d58159c0 749 Gene3D G3DSA:3.20.20.210 4 378 1.1E-110 T 28-03-2018 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 Pfam PF02872 5'-nucleotidase, C-terminal domain 315 476 2.0E-31 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 Gene3D G3DSA:3.60.21.10 2 304 8.9E-57 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 Pfam PF00149 Calcineurin-like phosphoesterase 5 235 2.1E-6 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 SUPERFAMILY SSF56300 2 304 3.64E-65 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 SUPERFAMILY SSF55816 302 504 1.27E-45 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 PRINTS PR01607 Apyrase family signature 449 468 1.2E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 PRINTS PR01607 Apyrase family signature 359 382 1.2E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 PRINTS PR01607 Apyrase family signature 182 199 1.2E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 PRINTS PR01607 Apyrase family signature 218 241 1.2E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 PRINTS PR01607 Apyrase family signature 2 20 1.2E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 PRINTS PR01607 Apyrase family signature 244 264 1.2E-22 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 ProSitePatterns PS00786 5'-nucleotidase signature 2. 86 97 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS03055 37976d41ddcf9981fa64df2947caf926 513 Gene3D G3DSA:3.90.780.10 305 512 4.0E-43 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS00940 0d9be326d90ea035a2a8e75fbbec80e2 264 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 3 261 30.535 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CWR44_RS00940 0d9be326d90ea035a2a8e75fbbec80e2 264 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 23 261 1.5E-72 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CWR44_RS00940 0d9be326d90ea035a2a8e75fbbec80e2 264 Gene3D G3DSA:3.10.20.10 29 110 1.7E-17 T 28-03-2018 CWR44_RS00940 0d9be326d90ea035a2a8e75fbbec80e2 264 Pfam PF02634 FdhD/NarQ family 27 260 4.7E-72 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CWR44_RS00940 0d9be326d90ea035a2a8e75fbbec80e2 264 SUPERFAMILY SSF53927 8 260 3.61E-73 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR44_RS00940 0d9be326d90ea035a2a8e75fbbec80e2 264 PIRSF PIRSF015626 1 263 8.9E-74 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CWR44_RS00940 0d9be326d90ea035a2a8e75fbbec80e2 264 Gene3D G3DSA:3.40.140.10 126 264 3.3E-47 T 28-03-2018 CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 4.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 4.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 4.6E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 Gene3D G3DSA:3.30.565.10 286 453 3.1E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 SMART SM00387 344 453 1.3E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 Gene3D G3DSA:1.10.287.130 223 285 7.3E-15 T 28-03-2018 CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 SMART SM00388 233 300 8.7E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 234 296 2.8E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 SUPERFAMILY SSF55874 290 452 2.23E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 451 5.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS10070 1c93477f2c6744acc11ec6e6406249ee 453 SUPERFAMILY SSF47384 216 296 1.84E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS10200 4e376d90b484fb83e47c8113456451c1 112 PIRSF PIRSF029938 1 112 1.3E-41 T 28-03-2018 IPR011229 Cell cycle protein GpsB CWR44_RS10200 4e376d90b484fb83e47c8113456451c1 112 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 42 1.6E-14 T 28-03-2018 IPR019933 DivIVA domain CWR44_RS10200 4e376d90b484fb83e47c8113456451c1 112 Pfam PF05103 DivIVA protein 8 69 1.4E-11 T 28-03-2018 IPR007793 DivIVA family CWR44_RS10200 4e376d90b484fb83e47c8113456451c1 112 Gene3D G3DSA:1.20.5.170 16 76 7.9E-5 T 28-03-2018 CWR44_RS10200 4e376d90b484fb83e47c8113456451c1 112 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 1 112 22.671 T 28-03-2018 IPR011229 Cell cycle protein GpsB CWR44_RS03150 9de78c51b2f561980da533595724ad82 324 SUPERFAMILY SSF56235 2 315 1.62E-94 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS03150 9de78c51b2f561980da533595724ad82 324 Gene3D G3DSA:3.60.60.10 1 313 3.4E-75 T 28-03-2018 CWR44_RS03150 9de78c51b2f561980da533595724ad82 324 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 311 2.2E-69 T 28-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CWR44_RS06405 4776de84e42ea0035cc6506cb9156601 162 Pfam PF04306 Protein of unknown function (DUF456) 22 157 1.4E-34 T 28-03-2018 IPR007403 Protein of unknown function DUF456 CWR44_RS01735 86b74aa86935a591e8d801c7207f4c8e 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 211 1.0E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS01735 86b74aa86935a591e8d801c7207f4c8e 228 SUPERFAMILY SSF161098 18 202 8.9E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS01735 86b74aa86935a591e8d801c7207f4c8e 228 Gene3D G3DSA:1.10.3720.10 4 217 8.1E-28 T 28-03-2018 CWR44_RS06960 b1a619dfd5ef26ea29c38881df93fcf7 246 SUPERFAMILY SSF53474 14 242 1.09E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS06960 b1a619dfd5ef26ea29c38881df93fcf7 246 PIRSF PIRSF017388 1 244 5.2E-88 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 CWR44_RS06960 b1a619dfd5ef26ea29c38881df93fcf7 246 Pfam PF12146 Serine aminopeptidase, S33 15 226 4.0E-16 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CWR44_RS06960 b1a619dfd5ef26ea29c38881df93fcf7 246 Gene3D G3DSA:3.40.50.1820 1 244 3.2E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 Pfam PF01467 Cytidylyltransferase-like 8 135 7.3E-17 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 64 7.7E-14 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 114 136 9.8E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 87 103 9.8E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 4 22 9.8E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 22 43 9.8E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 51 75 9.8E-50 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 Gene3D G3DSA:3.40.50.620 2 160 3.8E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 4 160 34.908 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 SUPERFAMILY SSF52374 3 158 7.51E-42 T 28-03-2018 CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 13 70 8.0E-5 T 28-03-2018 CWR44_RS08140 9c3fef2c67b41d7d145e1a50620e73dc 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 6 159 4.9E-59 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CWR44_RS01080 9b4b70615205b3b327d59616c4ae426d 350 SUPERFAMILY SSF51445 1 229 2.84E-60 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWR44_RS01080 9b4b70615205b3b327d59616c4ae426d 350 Pfam PF05913 Bacterial protein of unknown function (DUF871) 1 343 6.9E-92 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CWR44_RS01080 9b4b70615205b3b327d59616c4ae426d 350 Gene3D G3DSA:2.40.100.10 235 345 7.4E-29 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS01080 9b4b70615205b3b327d59616c4ae426d 350 Gene3D G3DSA:3.20.20.70 1 228 2.5E-60 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS01080 9b4b70615205b3b327d59616c4ae426d 350 SUPERFAMILY SSF50891 230 344 1.97E-32 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 403 420 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 SUPERFAMILY SSF53697 4 442 8.62E-139 T 28-03-2018 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 Gene3D G3DSA:3.40.50.10490 1 60 1.3E-9 T 28-03-2018 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 Gene3D G3DSA:3.40.50.10490 61 202 1.7E-44 T 28-03-2018 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 Pfam PF00342 Phosphoglucose isomerase 75 421 4.3E-22 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 Gene3D G3DSA:3.40.50.10490 203 429 6.8E-74 T 28-03-2018 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 193 211 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 403 416 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 371 389 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 268 289 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 PRINTS PR00662 Glucose-6-phosphate isomerase signature 389 403 2.3E-23 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 197 210 - T 28-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS07380 fb403d5660fdfc757d42d7315cc6d206 443 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 430 24.891 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS10325 d3c19263016ec123fc48a09f65c4b5d9 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CWR44_RS10325 d3c19263016ec123fc48a09f65c4b5d9 90 SUPERFAMILY SSF47729 1 90 1.62E-35 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CWR44_RS10325 d3c19263016ec123fc48a09f65c4b5d9 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.2E-37 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWR44_RS10325 d3c19263016ec123fc48a09f65c4b5d9 90 SMART SM00411 1 90 5.7E-51 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWR44_RS10325 d3c19263016ec123fc48a09f65c4b5d9 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.1E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWR44_RS10325 d3c19263016ec123fc48a09f65c4b5d9 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.1E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWR44_RS10325 d3c19263016ec123fc48a09f65c4b5d9 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.1E-21 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CWR44_RS10325 d3c19263016ec123fc48a09f65c4b5d9 90 Gene3D G3DSA:4.10.520.10 1 90 2.0E-38 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 Gene3D G3DSA:1.20.120.620 384 481 3.4E-14 T 28-03-2018 CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 SMART SM00387 762 874 4.2E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 Gene3D G3DSA:3.40.50.300 7 135 4.1E-16 T 28-03-2018 CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 SMART SM00388 650 718 2.2E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 SUPERFAMILY SSF47384 646 718 5.49E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 Pfam PF00512 His Kinase A (phospho-acceptor) domain 651 717 2.0E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 Gene3D G3DSA:1.10.287.130 653 714 6.1E-13 T 28-03-2018 CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 Gene3D G3DSA:3.30.565.10 715 882 7.4E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 Gene3D G3DSA:3.40.50.620 210 348 1.4E-6 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 Pfam PF13493 Domain of unknown function (DUF4118) 384 491 2.4E-20 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 Gene3D G3DSA:3.30.450.40 482 652 0.0067 T 28-03-2018 IPR029016 GAF domain-like CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 SUPERFAMILY SSF55874 708 872 7.6E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 763 871 7.4E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04065 ad9a0cedb22a55ba197ab033a78956df 889 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 7 214 4.7E-81 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 ProSitePatterns PS00674 AAA-protein family signature. 304 322 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 SUPERFAMILY SSF52540 158 405 2.22E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 Gene3D G3DSA:1.10.8.60 350 427 6.4E-24 T 28-03-2018 CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 SMART SM00382 197 336 1.4E-26 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 Pfam PF06480 FtsH Extracellular 9 102 1.5E-11 T 28-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 112 605 4.9E-239 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 Gene3D G3DSA:3.40.50.300 141 349 3.9E-65 T 28-03-2018 CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 201 333 2.8E-46 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 619 37.568 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 SUPERFAMILY SSF140990 415 607 8.63E-67 T 28-03-2018 CWR44_RS05385 593efbf5507dafac9b79dd60d55ceaf5 727 Pfam PF01434 Peptidase family M41 395 604 7.8E-83 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CWR44_RS00385 a01e4a152fb99557a2f190cae46c0e9c 286 Gene3D G3DSA:3.40.50.1000 1 274 5.1E-32 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS00385 a01e4a152fb99557a2f190cae46c0e9c 286 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 8 252 2.3E-23 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR44_RS00385 a01e4a152fb99557a2f190cae46c0e9c 286 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 9 280 4.9E-50 T 28-03-2018 IPR000150 Cof family GO:0016787 CWR44_RS00385 a01e4a152fb99557a2f190cae46c0e9c 286 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 280 1.2E-52 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS00385 a01e4a152fb99557a2f190cae46c0e9c 286 SUPERFAMILY SSF56784 2 285 1.01E-57 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 30 48 3.4E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 7 25 3.4E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 116 135 3.4E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 75 93 3.4E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 51 69 3.4E-43 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 3 153 34.888 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 PIRSF PIRSF006160 3 154 2.4E-66 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 10 143 3.0E-76 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 SUPERFAMILY SSF63411 3 150 4.58E-64 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 5 148 4.7E-56 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS00300 9292085f85a1a2a64728da1f854faa3c 156 Gene3D G3DSA:3.30.1360.80 5 151 2.1E-59 T 28-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS01875 663749cb9854e8a2e9f07040bfc47cea 422 Pfam PF12102 Domain of unknown function (DUF3578) 11 200 3.2E-39 T 28-03-2018 IPR021961 Protein of unknown function DUF3578 CWR44_RS01875 663749cb9854e8a2e9f07040bfc47cea 422 Pfam PF13020 Domain of unknown function (DUF3883) 280 388 9.5E-15 T 28-03-2018 IPR024975 Domain of unknown function DUF3883 CWR44_RS00900 f5da7450052a76d063a856b6840e0576 156 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 2 136 3.9E-36 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CWR44_RS00900 f5da7450052a76d063a856b6840e0576 156 Gene3D G3DSA:3.40.50.300 1 154 3.0E-15 T 28-03-2018 CWR44_RS00900 f5da7450052a76d063a856b6840e0576 156 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 2 121 6.1E-26 T 28-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CWR44_RS00900 f5da7450052a76d063a856b6840e0576 156 SUPERFAMILY SSF52540 2 121 4.29E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07050 a6818dd5a91ba59e3f15c194a056b130 202 PIRSF PIRSF000709 1 156 6.4E-11 T 28-03-2018 CWR44_RS07050 a6818dd5a91ba59e3f15c194a056b130 202 Gene3D G3DSA:3.40.50.1240 1 198 1.9E-40 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWR44_RS07050 a6818dd5a91ba59e3f15c194a056b130 202 SUPERFAMILY SSF53254 1 184 1.01E-45 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWR44_RS07050 a6818dd5a91ba59e3f15c194a056b130 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 188 2.3E-38 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWR44_RS07050 a6818dd5a91ba59e3f15c194a056b130 202 SMART SM00855 4 154 6.3E-20 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWR44_RS07050 a6818dd5a91ba59e3f15c194a056b130 202 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CWR44_RS10670 8a8993d7267a970b8a5a625d251d21a8 485 SUPERFAMILY SSF144091 153 337 8.11E-43 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CWR44_RS10670 8a8993d7267a970b8a5a625d251d21a8 485 Gene3D G3DSA:1.25.40.10 333 484 3.2E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS10670 8a8993d7267a970b8a5a625d251d21a8 485 Gene3D G3DSA:1.20.1540.10 153 332 3.2E-41 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CWR44_RS10670 8a8993d7267a970b8a5a625d251d21a8 485 SUPERFAMILY SSF48452 369 479 2.19E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS10670 8a8993d7267a970b8a5a625d251d21a8 485 Pfam PF01694 Rhomboid family 198 333 5.7E-35 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CWR44_RS03220 3c8b41a7f1c4ac5bc29b60aafb33c068 510 Pfam PF00474 Sodium:solute symporter family 39 442 3.4E-38 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR44_RS03220 3c8b41a7f1c4ac5bc29b60aafb33c068 510 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 39 442 8.9E-65 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR44_RS10280 ebe2c5b81ca777f4cbd1be020e5df796 178 PIRSF PIRSF007165 1 178 3.5E-44 T 28-03-2018 IPR011188 Uncharacterised protein family UPF0302 CWR44_RS10280 ebe2c5b81ca777f4cbd1be020e5df796 178 SMART SM00914 136 172 2.8E-8 T 28-03-2018 IPR014957 IDEAL domain CWR44_RS10280 ebe2c5b81ca777f4cbd1be020e5df796 178 Pfam PF08858 IDEAL domain 147 172 8.5E-7 T 28-03-2018 IPR014957 IDEAL domain CWR44_RS10280 ebe2c5b81ca777f4cbd1be020e5df796 178 Pfam PF08864 UPF0302 domain 9 106 1.1E-24 T 28-03-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal CWR44_RS09930 ed45d7cb6299b3dc6580ba4628f7f4a0 291 ProSitePatterns PS00211 ABC transporters family signature. 188 202 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS09930 ed45d7cb6299b3dc6580ba4628f7f4a0 291 Gene3D G3DSA:3.40.50.300 30 289 3.1E-59 T 28-03-2018 CWR44_RS09930 ed45d7cb6299b3dc6580ba4628f7f4a0 291 SMART SM00382 69 262 8.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS09930 ed45d7cb6299b3dc6580ba4628f7f4a0 291 SUPERFAMILY SSF52540 36 278 3.67E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS09930 ed45d7cb6299b3dc6580ba4628f7f4a0 291 Pfam PF00005 ABC transporter 60 216 1.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS09930 ed45d7cb6299b3dc6580ba4628f7f4a0 291 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 45 291 1.2E-125 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CWR44_RS03090 34c36c5e605389f8bf1104be92603b6a 281 SUPERFAMILY SSF52540 3 224 3.45E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03090 34c36c5e605389f8bf1104be92603b6a 281 Gene3D G3DSA:3.40.50.300 1 263 5.7E-51 T 28-03-2018 CWR44_RS03090 34c36c5e605389f8bf1104be92603b6a 281 Pfam PF00005 ABC transporter 21 160 3.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS03090 34c36c5e605389f8bf1104be92603b6a 281 SMART SM00382 30 208 1.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS02670 86e52a9c2d1ba01c0dfb4a8743f90417 222 SMART SM00448 1 111 4.9E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS02670 86e52a9c2d1ba01c0dfb4a8743f90417 222 Pfam PF00072 Response regulator receiver domain 3 111 6.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS02670 86e52a9c2d1ba01c0dfb4a8743f90417 222 SUPERFAMILY SSF52172 1 167 4.69E-31 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS02670 86e52a9c2d1ba01c0dfb4a8743f90417 222 Gene3D G3DSA:3.40.50.2300 1 122 5.4E-29 T 28-03-2018 CWR44_RS02670 86e52a9c2d1ba01c0dfb4a8743f90417 222 SUPERFAMILY SSF46894 145 220 7.82E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS02670 86e52a9c2d1ba01c0dfb4a8743f90417 222 SMART SM00862 146 221 6.8E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS02670 86e52a9c2d1ba01c0dfb4a8743f90417 222 Gene3D G3DSA:1.10.10.10 123 222 7.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02670 86e52a9c2d1ba01c0dfb4a8743f90417 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 5.4E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS10390 108f8e35e6849e0fa2378d493f768a78 241 SMART SM00448 3 113 1.5E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS10390 108f8e35e6849e0fa2378d493f768a78 241 Gene3D G3DSA:3.40.50.2300 2 131 1.4E-39 T 28-03-2018 CWR44_RS10390 108f8e35e6849e0fa2378d493f768a78 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 6.1E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS10390 108f8e35e6849e0fa2378d493f768a78 241 Pfam PF00072 Response regulator receiver domain 5 113 2.4E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS10390 108f8e35e6849e0fa2378d493f768a78 241 SUPERFAMILY SSF52172 5 189 9.66E-43 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS10390 108f8e35e6849e0fa2378d493f768a78 241 Gene3D G3DSA:1.10.10.10 132 238 7.2E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10390 108f8e35e6849e0fa2378d493f768a78 241 SMART SM00862 154 231 8.6E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS07085 dcd0c3d7e1c4b601432df7d72b71cdae 107 SUPERFAMILY SSF52833 4 104 9.19E-25 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS07085 dcd0c3d7e1c4b601432df7d72b71cdae 107 Pfam PF00085 Thioredoxin 6 101 1.2E-17 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWR44_RS07085 dcd0c3d7e1c4b601432df7d72b71cdae 107 Gene3D G3DSA:3.40.30.10 1 107 2.1E-21 T 28-03-2018 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 Pfam PF00696 Amino acid kinase family 3 282 1.5E-29 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 PIRSF PIRSF000723 1 309 2.5E-129 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 PRINTS PR01469 Bacterial carbamate kinase signature 263 278 1.1E-59 T 28-03-2018 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 PRINTS PR01469 Bacterial carbamate kinase signature 155 174 1.1E-59 T 28-03-2018 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 PRINTS PR01469 Bacterial carbamate kinase signature 208 223 1.1E-59 T 28-03-2018 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 PRINTS PR01469 Bacterial carbamate kinase signature 71 89 1.1E-59 T 28-03-2018 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 PRINTS PR01469 Bacterial carbamate kinase signature 178 196 1.1E-59 T 28-03-2018 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 PRINTS PR01469 Bacterial carbamate kinase signature 38 57 1.1E-59 T 28-03-2018 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 PRINTS PR01469 Bacterial carbamate kinase signature 106 125 1.1E-59 T 28-03-2018 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 TIGRFAM TIGR00746 arcC: carbamate kinase 3 308 5.8E-116 T 28-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 Gene3D G3DSA:3.40.1160.10 1 309 2.7E-58 T 28-03-2018 CWR44_RS03340 c234b63c4d3e4564b62954ecc831cb30 309 SUPERFAMILY SSF53633 1 307 1.14E-84 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR44_RS07210 c0834eac9d92b6ce36abec95c9d63c9b 263 PIRSF PIRSF000915 1 259 1.8E-56 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CWR44_RS07210 c0834eac9d92b6ce36abec95c9d63c9b 263 SUPERFAMILY SSF56784 3 250 7.72E-66 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS07210 c0834eac9d92b6ce36abec95c9d63c9b 263 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 106 7.8E-26 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CWR44_RS07210 c0834eac9d92b6ce36abec95c9d63c9b 263 Gene3D G3DSA:3.40.50.1000 72 182 3.1E-31 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS07210 c0834eac9d92b6ce36abec95c9d63c9b 263 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 250 1.7E-99 T 28-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 CWR44_RS07210 c0834eac9d92b6ce36abec95c9d63c9b 263 Pfam PF13242 HAD-hyrolase-like 180 251 9.8E-18 T 28-03-2018 CWR44_RS07210 c0834eac9d92b6ce36abec95c9d63c9b 263 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 229 2.0E-40 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CWR44_RS08790 06ec8d299e2f4380834bb0bef7af27a5 805 Gene3D G3DSA:1.10.10.10 752 792 4.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS08790 06ec8d299e2f4380834bb0bef7af27a5 805 Pfam PF09397 Ftsk gamma domain 738 798 3.7E-28 T 28-03-2018 IPR018541 FtsK gamma domain CWR44_RS08790 06ec8d299e2f4380834bb0bef7af27a5 805 SUPERFAMILY SSF46785 737 802 1.36E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS08790 06ec8d299e2f4380834bb0bef7af27a5 805 Gene3D G3DSA:3.40.50.300 210 751 1.4E-52 T 28-03-2018 CWR44_RS08790 06ec8d299e2f4380834bb0bef7af27a5 805 SMART SM00843 736 801 7.8E-34 T 28-03-2018 IPR018541 FtsK gamma domain CWR44_RS08790 06ec8d299e2f4380834bb0bef7af27a5 805 SUPERFAMILY SSF52540 419 712 5.18E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08790 06ec8d299e2f4380834bb0bef7af27a5 805 SMART SM00382 479 661 8.9E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS08790 06ec8d299e2f4380834bb0bef7af27a5 805 Pfam PF01580 FtsK/SpoIIIE family 457 640 5.3E-60 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CWR44_RS02405 002332b3acffb71bc7c323ac034d6ef7 295 SUPERFAMILY SSF57783 2 36 2.83E-6 T 28-03-2018 CWR44_RS02405 002332b3acffb71bc7c323ac034d6ef7 295 Gene3D G3DSA:2.20.28.20 2 27 7.0E-5 T 28-03-2018 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Pfam PF04563 RNA polymerase beta subunit 28 453 8.5E-30 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 SUPERFAMILY SSF64484 14 286 0.0 T 28-03-2018 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 SUPERFAMILY SSF64484 377 1155 0.0 T 28-03-2018 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Pfam PF10385 RNA polymerase beta subunit external 1 domain 546 613 2.3E-25 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Pfam PF04560 RNA polymerase Rpb2, domain 7 1071 1146 8.9E-26 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Gene3D G3DSA:2.40.50.100 672 750 2.0E-22 T 28-03-2018 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 2.5E-28 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Pfam PF04561 RNA polymerase Rpb2, domain 2 373 409 1.2E-4 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Gene3D G3DSA:2.40.270.10 847 1055 2.5E-77 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Pfam PF00562 RNA polymerase Rpb2, domain 6 675 1069 8.0E-166 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 ProSitePatterns PS01166 RNA polymerases beta chain signature. 922 934 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Pfam PF04565 RNA polymerase Rpb2, domain 3 468 536 5.3E-30 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Gene3D G3DSA:2.40.270.10 751 846 2.9E-11 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Gene3D G3DSA:3.90.1800.10 1072 1115 1.0E-11 T 28-03-2018 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Gene3D G3DSA:3.90.1100.10 20 240 2.6E-58 T 28-03-2018 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Gene3D G3DSA:3.90.1100.10 601 670 1.1E-13 T 28-03-2018 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Gene3D G3DSA:3.90.1100.10 293 600 3.3E-82 T 28-03-2018 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1147 12.53 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05635 30b7564d0a6b4e5a2d9e1c8c77fd5b8d 1183 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 205 895 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 2.4E-67 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 Gene3D G3DSA:3.40.50.10860 11 139 2.9E-49 T 28-03-2018 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 3.3E-40 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 Gene3D G3DSA:3.40.50.720 140 263 2.3E-42 T 28-03-2018 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 SUPERFAMILY SSF53223 2 121 8.34E-40 T 28-03-2018 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 SUPERFAMILY SSF51735 122 278 3.19E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 38.128 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.1E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.1E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.1E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.1E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.1E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.1E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR44_RS07820 43758c2966d145d4dba4c01bd1a494d9 285 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.1E-80 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CWR44_RS04370 0f3d958c0b783688d4ebb515ab9d51c9 427 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR44_RS04370 0f3d958c0b783688d4ebb515ab9d51c9 427 Gene3D G3DSA:3.40.440.10 1 150 3.5E-52 T 28-03-2018 CWR44_RS04370 0f3d958c0b783688d4ebb515ab9d51c9 427 Gene3D G3DSA:3.40.440.10 151 264 9.1E-25 T 28-03-2018 CWR44_RS04370 0f3d958c0b783688d4ebb515ab9d51c9 427 SUPERFAMILY SSF52540 1 426 1.17E-171 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04370 0f3d958c0b783688d4ebb515ab9d51c9 427 Gene3D G3DSA:3.90.170.10 265 427 4.1E-68 T 28-03-2018 CWR44_RS04370 0f3d958c0b783688d4ebb515ab9d51c9 427 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR44_RS04370 0f3d958c0b783688d4ebb515ab9d51c9 427 SMART SM00788 3 422 8.9E-282 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR44_RS04370 0f3d958c0b783688d4ebb515ab9d51c9 427 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 427 202.129 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR44_RS04370 0f3d958c0b783688d4ebb515ab9d51c9 427 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 424 1.5E-179 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR44_RS04370 0f3d958c0b783688d4ebb515ab9d51c9 427 Pfam PF00709 Adenylosuccinate synthetase 4 420 1.2E-178 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 Pfam PF00117 Glutamine amidotransferase class-I 4 182 4.8E-36 T 28-03-2018 IPR017926 Glutamine amidotransferase CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 71 87 2.1E-6 T 28-03-2018 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 42 56 2.1E-6 T 28-03-2018 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 183 6.6E-45 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 SUPERFAMILY SSF52317 1 187 6.06E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 Gene3D G3DSA:3.40.50.880 1 188 2.1E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00097 Anthranilate synthase component II signature 96 104 5.9E-32 T 28-03-2018 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.9E-32 T 28-03-2018 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00097 Anthranilate synthase component II signature 117 129 5.9E-32 T 28-03-2018 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00097 Anthranilate synthase component II signature 71 82 5.9E-32 T 28-03-2018 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00097 Anthranilate synthase component II signature 161 174 5.9E-32 T 28-03-2018 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00097 Anthranilate synthase component II signature 45 54 5.9E-32 T 28-03-2018 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00096 Glutamine amidotransferase superfamily signature 45 54 1.3E-12 T 28-03-2018 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00096 Glutamine amidotransferase superfamily signature 71 82 1.3E-12 T 28-03-2018 CWR44_RS09860 4434781da518cc4f5259d194ab22f1eb 199 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 1.3E-12 T 28-03-2018 CWR44_RS09965 01ab82640f7297eef2391e909098e535 329 PIRSF PIRSF000148 1 327 1.8E-109 T 28-03-2018 CWR44_RS09965 01ab82640f7297eef2391e909098e535 329 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 324 6.5E-113 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR44_RS09965 01ab82640f7297eef2391e909098e535 329 SMART SM00859 3 119 1.3E-28 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CWR44_RS09965 01ab82640f7297eef2391e909098e535 329 SUPERFAMILY SSF55347 125 310 3.67E-64 T 28-03-2018 CWR44_RS09965 01ab82640f7297eef2391e909098e535 329 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 135 309 6.5E-47 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CWR44_RS09965 01ab82640f7297eef2391e909098e535 329 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 323 33.095 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CWR44_RS09965 01ab82640f7297eef2391e909098e535 329 SUPERFAMILY SSF51735 1 152 6.86E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS09965 01ab82640f7297eef2391e909098e535 329 Gene3D G3DSA:3.30.360.10 137 306 1.4E-60 T 28-03-2018 CWR44_RS09965 01ab82640f7297eef2391e909098e535 329 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 117 7.9E-29 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CWR44_RS09965 01ab82640f7297eef2391e909098e535 329 Gene3D G3DSA:3.40.50.720 1 136 4.3E-28 T 28-03-2018 CWR44_RS01415 4ba5126cf81255ca2fcb644a977e25c7 425 Pfam PF12698 ABC-2 family transporter protein 9 403 3.5E-24 T 28-03-2018 CWR44_RS01415 4ba5126cf81255ca2fcb644a977e25c7 425 Gene3D G3DSA:3.40.1710.10 28 246 1.1E-26 T 28-03-2018 CWR44_RS11230 3e2c07eace2225d2a24bdd2bf426e975 195 SUPERFAMILY SSF52540 4 195 2.14E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11230 3e2c07eace2225d2a24bdd2bf426e975 195 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 13 195 27.711 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CWR44_RS11230 3e2c07eace2225d2a24bdd2bf426e975 195 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 10 191 3.8E-68 T 28-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CWR44_RS11230 3e2c07eace2225d2a24bdd2bf426e975 195 Gene3D G3DSA:3.40.50.300 6 75 1.1E-12 T 28-03-2018 CWR44_RS11230 3e2c07eace2225d2a24bdd2bf426e975 195 Pfam PF01926 50S ribosome-binding GTPase 27 145 1.6E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS11230 3e2c07eace2225d2a24bdd2bf426e975 195 Gene3D G3DSA:3.40.50.300 76 193 1.5E-13 T 28-03-2018 CWR44_RS06775 0499fd981bc5627c6f77bc874d9410a3 361 ProSitePatterns PS01348 MraY family signature 2. 145 156 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR44_RS06775 0499fd981bc5627c6f77bc874d9410a3 361 Pfam PF00953 Glycosyl transferase family 4 73 225 3.5E-41 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWR44_RS02450 3040eb07f838bf090f44b820682d8cfe 441 Gene3D G3DSA:3.20.20.80 66 422 8.0E-14 T 28-03-2018 CWR44_RS02450 3040eb07f838bf090f44b820682d8cfe 441 Pfam PF13200 Putative glycosyl hydrolase domain 70 394 6.7E-121 T 28-03-2018 IPR025275 Putative glycosyl hydrolase domain DUF4015 CWR44_RS02450 3040eb07f838bf090f44b820682d8cfe 441 SUPERFAMILY SSF51445 83 401 1.0E-10 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWR44_RS07140 025f0e8d979b06d9b9fd2e31826d50df 253 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 5 245 2.2E-112 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CWR44_RS07140 025f0e8d979b06d9b9fd2e31826d50df 253 Pfam PF00005 ABC transporter 20 172 8.3E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS07140 025f0e8d979b06d9b9fd2e31826d50df 253 SUPERFAMILY SSF52540 4 232 6.81E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07140 025f0e8d979b06d9b9fd2e31826d50df 253 Gene3D G3DSA:3.40.50.300 2 251 1.4E-44 T 28-03-2018 CWR44_RS07140 025f0e8d979b06d9b9fd2e31826d50df 253 SMART SM00382 29 224 9.1E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS07140 025f0e8d979b06d9b9fd2e31826d50df 253 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 PRINTS PR00869 DNA-polymerase family X signature 193 201 5.2E-5 T 28-03-2018 IPR022312 DNA polymerase family X GO:0003677|GO:0034061 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 PRINTS PR00869 DNA-polymerase family X signature 179 193 5.2E-5 T 28-03-2018 IPR022312 DNA polymerase family X GO:0003677|GO:0034061 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 PRINTS PR00869 DNA-polymerase family X signature 295 313 5.2E-5 T 28-03-2018 IPR022312 DNA polymerase family X GO:0003677|GO:0034061 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 Pfam PF14716 Helix-hairpin-helix domain 4 67 5.0E-18 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 SUPERFAMILY SSF47802 2 80 5.23E-20 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 SMART SM00483 1 314 8.2E-43 T 28-03-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 Gene3D G3DSA:3.30.460.10 153 245 1.7E-17 T 28-03-2018 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 Pfam PF14791 DNA polymerase beta thumb 254 314 1.3E-15 T 28-03-2018 IPR029398 DNA polymerase beta, thumb domain CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 SMART SM00278 88 107 31.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 SMART SM00278 123 142 160.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 SMART SM00278 48 67 87.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 Pfam PF02811 PHP domain 335 509 3.8E-7 T 28-03-2018 IPR004013 PHP domain GO:0003824 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 SUPERFAMILY SSF89550 333 566 1.31E-48 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 PIRSF PIRSF005047 1 566 2.4E-223 T 28-03-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 Gene3D G3DSA:3.30.210.10 252 313 2.4E-15 T 28-03-2018 IPR029398 DNA polymerase beta, thumb domain CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 Gene3D G3DSA:1.10.150.110 1 82 1.5E-18 T 28-03-2018 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 SUPERFAMILY SSF81301 153 314 9.81E-42 T 28-03-2018 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 Gene3D G3DSA:3.20.20.140 322 568 4.7E-42 T 28-03-2018 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 Gene3D G3DSA:1.10.150.20 86 146 3.2E-11 T 28-03-2018 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 180 199 1.2E-6 T 28-03-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 296 313 1.2E-6 T 28-03-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 55 72 1.2E-6 T 28-03-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08195 203ce1b77fcf38b0c33645e440daa89d 570 SMART SM00481 334 413 4.1E-11 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 SUPERFAMILY SSF52016 638 898 1.57E-83 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 Gene3D G3DSA:3.30.499.10 373 584 5.9E-65 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 ProSitePatterns PS00450 Aconitase family signature 1. 435 451 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 Gene3D G3DSA:3.30.499.10 33 239 2.4E-69 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 Gene3D G3DSA:3.40.1060.10 240 372 5.7E-44 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 SUPERFAMILY SSF53732 9 635 4.45E-220 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 Pfam PF00330 Aconitase family (aconitate hydratase) 76 570 4.7E-177 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 ProSitePatterns PS01244 Aconitase family signature 2. 501 514 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 899 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 Gene3D G3DSA:3.20.19.10 662 900 5.8E-89 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 PRINTS PR00415 Aconitase family signature 439 450 5.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 PRINTS PR00415 Aconitase family signature 501 514 5.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 PRINTS PR00415 Aconitase family signature 217 232 5.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 PRINTS PR00415 Aconitase family signature 279 292 5.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 PRINTS PR00415 Aconitase family signature 170 178 5.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 PRINTS PR00415 Aconitase family signature 293 306 5.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 PRINTS PR00415 Aconitase family signature 146 159 5.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 PRINTS PR00415 Aconitase family signature 203 216 5.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 PRINTS PR00415 Aconitase family signature 373 387 5.6E-40 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS09775 8cb48134eb5d0e7fe6390ac390babc7a 901 Pfam PF00694 Aconitase C-terminal domain 701 827 1.3E-41 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS08880 a1620427f9d28ae09b8ee148f838dd3b 121 Gene3D G3DSA:1.20.1500.10 6 114 2.7E-22 T 28-03-2018 IPR023378 YheA/YmcA-like domain CWR44_RS08880 a1620427f9d28ae09b8ee148f838dd3b 121 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 7 111 2.0E-16 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CWR44_RS08880 a1620427f9d28ae09b8ee148f838dd3b 121 SUPERFAMILY SSF158622 1 115 1.05E-29 T 28-03-2018 IPR023378 YheA/YmcA-like domain CWR44_RS08880 a1620427f9d28ae09b8ee148f838dd3b 121 PIRSF PIRSF021287 1 121 4.1E-43 T 28-03-2018 IPR016783 Biofilm formation YmcA CWR44_RS07145 1d647dc8b44f262d9e6bed7d9c2f1aaa 435 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 150 424 3.1E-72 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CWR44_RS07145 1d647dc8b44f262d9e6bed7d9c2f1aaa 435 Pfam PF01458 Uncharacterized protein family (UPF0051) 183 408 4.6E-59 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CWR44_RS07145 1d647dc8b44f262d9e6bed7d9c2f1aaa 435 SUPERFAMILY SSF101960 12 433 2.88E-115 T 28-03-2018 CWR44_RS08910 d6daf8694e3efadebf08d23e23ee3698 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 251 9.5E-88 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CWR44_RS08910 d6daf8694e3efadebf08d23e23ee3698 499 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 58.895 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CWR44_RS08910 d6daf8694e3efadebf08d23e23ee3698 499 SUPERFAMILY SSF53067 254 492 1.57E-85 T 28-03-2018 CWR44_RS08910 d6daf8694e3efadebf08d23e23ee3698 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 449 1.8E-63 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CWR44_RS08910 d6daf8694e3efadebf08d23e23ee3698 499 SUPERFAMILY SSF53067 3 254 1.88E-95 T 28-03-2018 CWR44_RS08910 d6daf8694e3efadebf08d23e23ee3698 499 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 493 2.7E-228 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CWR44_RS08910 d6daf8694e3efadebf08d23e23ee3698 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR44_RS08910 d6daf8694e3efadebf08d23e23ee3698 499 Gene3D G3DSA:3.30.420.40 248 499 4.4E-80 T 28-03-2018 CWR44_RS08910 d6daf8694e3efadebf08d23e23ee3698 499 PIRSF PIRSF000538 2 497 2.4E-178 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR44_RS08910 d6daf8694e3efadebf08d23e23ee3698 499 Gene3D G3DSA:3.30.420.40 1 247 4.1E-86 T 28-03-2018 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 164 287 4.7E-10 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 SUPERFAMILY SSF55681 4 375 6.13E-126 T 28-03-2018 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 4 237 2.0E-87 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 SUPERFAMILY SSF52954 359 461 4.68E-34 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 Gene3D G3DSA:3.40.50.800 358 462 5.4E-28 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 326 338 4.4E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 407 426 4.4E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 149 161 4.4E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 219 229 4.4E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 24 38 4.4E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 170 187 4.4E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 PRINTS PR01043 Glycyl-tRNA synthetase signature 202 219 4.4E-53 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 Pfam PF03129 Anticodon binding domain 372 459 7.4E-24 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 2 462 51.022 T 28-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 Gene3D G3DSA:3.30.930.10 236 357 1.1E-43 T 28-03-2018 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 Gene3D G3DSA:3.30.930.10 2 103 2.3E-21 T 28-03-2018 CWR44_RS10750 6c49091fe664c204a0d2c67f409cab05 463 Gene3D G3DSA:3.30.930.10 104 235 5.5E-33 T 28-03-2018 CWR44_RS09900 e5e3c930b568cc4cd5ae19b735dfd06b 419 Pfam PF02388 FemAB family 6 411 1.7E-139 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CWR44_RS09900 e5e3c930b568cc4cd5ae19b735dfd06b 419 Gene3D G3DSA:3.40.630.30 1 170 6.4E-29 T 28-03-2018 CWR44_RS09900 e5e3c930b568cc4cd5ae19b735dfd06b 419 Gene3D G3DSA:3.40.630.30 171 387 4.7E-33 T 28-03-2018 CWR44_RS09900 e5e3c930b568cc4cd5ae19b735dfd06b 419 SUPERFAMILY SSF55729 171 246 4.24E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS09900 e5e3c930b568cc4cd5ae19b735dfd06b 419 SUPERFAMILY SSF55729 309 408 4.24E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS09900 e5e3c930b568cc4cd5ae19b735dfd06b 419 SUPERFAMILY SSF55729 1 166 4.77E-47 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 SUPERFAMILY SSF69065 10 175 2.09E-51 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 Pfam PF14622 Ribonuclease-III-like 31 160 2.6E-36 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 SMART SM00535 32 167 3.8E-53 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 Gene3D G3DSA:1.10.1520.10 16 165 1.2E-41 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 SUPERFAMILY SSF54768 160 242 7.7E-21 T 28-03-2018 CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 SMART SM00358 173 240 2.5E-19 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 Hamap MF_00104 Ribonuclease 3 [rnc]. 20 236 29.759 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 Gene3D G3DSA:3.30.160.20 171 245 3.5E-20 T 28-03-2018 CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 Pfam PF00035 Double-stranded RNA binding motif 174 239 6.3E-15 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 ProSitePatterns PS00517 Ribonuclease III family signature. 56 64 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR44_RS08575 05e434eda2b1419825cfc9852ad28c30 245 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 22 239 3.3E-78 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 Pfam PF01751 Toprim domain 430 541 2.5E-17 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR00418 DNA topoisomerase II family signature 121 135 1.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR00418 DNA topoisomerase II family signature 78 91 1.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR00418 DNA topoisomerase II family signature 279 292 1.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR00418 DNA topoisomerase II family signature 431 445 1.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR00418 DNA topoisomerase II family signature 515 532 1.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR00418 DNA topoisomerase II family signature 43 58 1.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR00418 DNA topoisomerase II family signature 497 513 1.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR00418 DNA topoisomerase II family signature 535 547 1.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR00418 DNA topoisomerase II family signature 577 593 1.6E-70 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 SUPERFAMILY SSF55874 14 222 3.93E-72 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR01159 DNA gyrase subunit B signature 598 610 2.3E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR01159 DNA gyrase subunit B signature 371 385 2.3E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR01159 DNA gyrase subunit B signature 614 630 2.3E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR01159 DNA gyrase subunit B signature 385 405 2.3E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR01159 DNA gyrase subunit B signature 14 24 2.3E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR01159 DNA gyrase subunit B signature 231 253 2.3E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR01159 DNA gyrase subunit B signature 204 217 2.3E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR01159 DNA gyrase subunit B signature 189 204 2.3E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR01159 DNA gyrase subunit B signature 323 339 2.3E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 PRINTS PR01159 DNA gyrase subunit B signature 481 490 2.3E-74 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 SMART SM00387 39 183 1.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 Gene3D G3DSA:3.40.50.670 410 641 5.5E-103 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 Gene3D G3DSA:3.30.565.10 24 235 2.6E-74 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 ProSitePatterns PS00177 DNA topoisomerase II signature. 433 441 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 14 640 4.5E-300 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 Pfam PF00204 DNA gyrase B 232 401 8.3E-62 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 40 181 6.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 11 644 92.231 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 574 634 6.6E-30 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 SUPERFAMILY SSF56719 405 636 4.45E-91 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 SMART SM00433 43 638 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 Gene3D G3DSA:3.30.230.10 236 403 8.3E-63 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS04425 7e6b87b189e835e7ffd962e009bc36ad 644 SUPERFAMILY SSF54211 232 402 1.06E-58 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS12440 4c108b6857425204d4af02ceb047a6e2 273 TIGRFAM TIGR00552 nadE: NAD+ synthetase 22 263 7.6E-72 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CWR44_RS12440 4c108b6857425204d4af02ceb047a6e2 273 Gene3D G3DSA:3.40.50.620 3 271 8.7E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS12440 4c108b6857425204d4af02ceb047a6e2 273 Pfam PF02540 NAD synthase 25 264 1.0E-69 T 28-03-2018 IPR022310 NAD/GMP synthase CWR44_RS12440 4c108b6857425204d4af02ceb047a6e2 273 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 18 267 30.578 T 28-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CWR44_RS12440 4c108b6857425204d4af02ceb047a6e2 273 SUPERFAMILY SSF52402 4 268 3.67E-81 T 28-03-2018 CWR44_RS08495 a03475be9450a4bf1aa0bcaab1f81afe 364 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 17 363 2.8E-154 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS08495 a03475be9450a4bf1aa0bcaab1f81afe 364 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 18 360 71.953 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS08495 a03475be9450a4bf1aa0bcaab1f81afe 364 Pfam PF04055 Radical SAM superfamily 121 291 2.3E-18 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS08495 a03475be9450a4bf1aa0bcaab1f81afe 364 Pfam PF13394 4Fe-4S single cluster domain 126 227 2.2E-6 T 28-03-2018 CWR44_RS08495 a03475be9450a4bf1aa0bcaab1f81afe 364 Gene3D G3DSA:3.20.20.70 28 360 3.3E-41 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS08495 a03475be9450a4bf1aa0bcaab1f81afe 364 PIRSF PIRSF006004 9 364 1.6E-138 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS08495 a03475be9450a4bf1aa0bcaab1f81afe 364 SUPERFAMILY SSF102114 113 333 3.27E-16 T 28-03-2018 CWR44_RS09335 3465224e853f0f1b042dee8f1b096be4 425 Pfam PF00742 Homoserine dehydrogenase 137 315 7.0E-60 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWR44_RS09335 3465224e853f0f1b042dee8f1b096be4 425 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWR44_RS09335 3465224e853f0f1b042dee8f1b096be4 425 Gene3D G3DSA:3.40.50.720 1 157 6.0E-31 T 28-03-2018 CWR44_RS09335 3465224e853f0f1b042dee8f1b096be4 425 SUPERFAMILY SSF55347 137 302 2.16E-49 T 28-03-2018 CWR44_RS09335 3465224e853f0f1b042dee8f1b096be4 425 SUPERFAMILY SSF51735 1 158 3.38E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS09335 3465224e853f0f1b042dee8f1b096be4 425 PIRSF PIRSF000098 1 422 4.2E-133 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CWR44_RS09335 3465224e853f0f1b042dee8f1b096be4 425 Gene3D G3DSA:3.30.360.10 158 298 7.2E-49 T 28-03-2018 CWR44_RS09335 3465224e853f0f1b042dee8f1b096be4 425 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 128 8.7E-18 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CWR44_RS07825 f12376488571c34d458f8f926e3d3176 160 SUPERFAMILY SSF52255 2 159 5.36E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR44_RS07825 f12376488571c34d458f8f926e3d3176 160 Pfam PF00731 AIR carboxylase 2 148 8.9E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR44_RS07825 f12376488571c34d458f8f926e3d3176 160 PIRSF PIRSF001338 1 160 8.9E-70 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CWR44_RS07825 f12376488571c34d458f8f926e3d3176 160 SMART SM01001 1 152 2.7E-100 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR44_RS07825 f12376488571c34d458f8f926e3d3176 160 Gene3D G3DSA:3.40.50.7700 1 160 2.1E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR44_RS07825 f12376488571c34d458f8f926e3d3176 160 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 159 1.0E-65 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CWR44_RS07825 f12376488571c34d458f8f926e3d3176 160 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 156 32.204 T 28-03-2018 IPR033747 Class I PurE CWR44_RS12410 69570b7430d351369166f0fd37c54bde 731 Gene3D G3DSA:3.40.50.300 281 383 1.1E-28 T 28-03-2018 CWR44_RS12410 69570b7430d351369166f0fd37c54bde 731 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 270 2.3E-85 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CWR44_RS12410 69570b7430d351369166f0fd37c54bde 731 Pfam PF13361 UvrD-like helicase C-terminal domain 276 613 4.3E-79 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWR44_RS12410 69570b7430d351369166f0fd37c54bde 731 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 4 727 0.0 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CWR44_RS12410 69570b7430d351369166f0fd37c54bde 731 Gene3D G3DSA:3.40.50.300 384 684 2.3E-53 T 28-03-2018 CWR44_RS12410 69570b7430d351369166f0fd37c54bde 731 Gene3D G3DSA:3.40.50.300 138 280 4.5E-34 T 28-03-2018 CWR44_RS12410 69570b7430d351369166f0fd37c54bde 731 Gene3D G3DSA:3.40.50.300 1 137 2.0E-30 T 28-03-2018 CWR44_RS12410 69570b7430d351369166f0fd37c54bde 731 SUPERFAMILY SSF52540 1 640 2.1E-183 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04670 6a3c622025ed361b68d4d6d061c8a0fe 189 Pfam PF00072 Response regulator receiver domain 2 76 2.1E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS04670 6a3c622025ed361b68d4d6d061c8a0fe 189 SMART SM00862 112 185 5.2E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS04670 6a3c622025ed361b68d4d6d061c8a0fe 189 Pfam PF00486 Transcriptional regulatory protein, C terminal 115 185 4.5E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS04670 6a3c622025ed361b68d4d6d061c8a0fe 189 Gene3D G3DSA:1.10.10.10 89 189 8.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04670 6a3c622025ed361b68d4d6d061c8a0fe 189 SMART SM00448 1 76 8.4E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS04670 6a3c622025ed361b68d4d6d061c8a0fe 189 SUPERFAMILY SSF52172 2 92 4.55E-27 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS04670 6a3c622025ed361b68d4d6d061c8a0fe 189 SUPERFAMILY SSF46894 85 186 3.12E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS04670 6a3c622025ed361b68d4d6d061c8a0fe 189 Gene3D G3DSA:3.40.50.2300 1 88 8.0E-25 T 28-03-2018 CWR44_RS10760 237e7c4ccf3a606bab7ec86caecee4f4 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 166 6.6E-28 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR44_RS10760 237e7c4ccf3a606bab7ec86caecee4f4 299 Pfam PF07650 KH domain 206 283 5.3E-22 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS10760 237e7c4ccf3a606bab7ec86caecee4f4 299 Pfam PF01926 50S ribosome-binding GTPase 9 123 2.8E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS10760 237e7c4ccf3a606bab7ec86caecee4f4 299 Gene3D G3DSA:3.40.50.300 2 54 1.2E-12 T 28-03-2018 CWR44_RS10760 237e7c4ccf3a606bab7ec86caecee4f4 299 Hamap MF_00367 GTPase Era [era]. 4 294 38.752 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10760 237e7c4ccf3a606bab7ec86caecee4f4 299 SUPERFAMILY SSF54814 179 294 2.62E-41 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWR44_RS10760 237e7c4ccf3a606bab7ec86caecee4f4 299 SUPERFAMILY SSF52540 9 203 4.57E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10760 237e7c4ccf3a606bab7ec86caecee4f4 299 Gene3D G3DSA:3.40.50.300 55 177 2.6E-19 T 28-03-2018 CWR44_RS10760 237e7c4ccf3a606bab7ec86caecee4f4 299 Gene3D G3DSA:3.30.300.20 183 297 7.5E-45 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWR44_RS10760 237e7c4ccf3a606bab7ec86caecee4f4 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 7 277 6.0E-104 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS02740 af26782ea511adaabaf0689d3eefc9e8 340 Pfam PF08485 Polysaccharide biosynthesis protein C-terminal 284 331 8.1E-19 T 28-03-2018 IPR013692 UDP-glucose 4-epimerase CapD, C-terminal domain GO:0003978|GO:0009103 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344 CWR44_RS02740 af26782ea511adaabaf0689d3eefc9e8 340 Pfam PF02719 Polysaccharide biosynthesis protein 7 281 3.0E-106 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CWR44_RS02740 af26782ea511adaabaf0689d3eefc9e8 340 Gene3D G3DSA:3.40.50.720 1 330 4.3E-63 T 28-03-2018 CWR44_RS02740 af26782ea511adaabaf0689d3eefc9e8 340 SUPERFAMILY SSF51735 1 259 1.31E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS00795 73d58dc0f1e5c275d30b58f0585c99e4 220 Gene3D G3DSA:4.10.960.10 66 173 2.2E-32 T 28-03-2018 CWR44_RS00795 73d58dc0f1e5c275d30b58f0585c99e4 220 SUPERFAMILY SSF50447 1 219 2.47E-78 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWR44_RS00795 73d58dc0f1e5c275d30b58f0585c99e4 220 ProSitePatterns PS00474 Ribosomal protein L3 signature. 110 133 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site CWR44_RS00795 73d58dc0f1e5c275d30b58f0585c99e4 220 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 211 2.0E-84 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00795 73d58dc0f1e5c275d30b58f0585c99e4 220 Pfam PF00297 Ribosomal protein L3 103 190 5.7E-15 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00795 73d58dc0f1e5c275d30b58f0585c99e4 220 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 215 39.647 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10860 ca6e707b1153e71d4d9bc85ef755a2d7 726 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 204 371 5.0E-29 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CWR44_RS10860 ca6e707b1153e71d4d9bc85ef755a2d7 726 Pfam PF03772 Competence protein 183 437 1.2E-47 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CWR44_RS10860 ca6e707b1153e71d4d9bc85ef755a2d7 726 Pfam PF00753 Metallo-beta-lactamase superfamily 474 679 3.6E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS10860 ca6e707b1153e71d4d9bc85ef755a2d7 726 SMART SM00849 476 681 8.8E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS10860 ca6e707b1153e71d4d9bc85ef755a2d7 726 SUPERFAMILY SSF56281 468 718 9.04E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS10860 ca6e707b1153e71d4d9bc85ef755a2d7 726 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 173 709 1.9E-81 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CWR44_RS10860 ca6e707b1153e71d4d9bc85ef755a2d7 726 Gene3D G3DSA:3.60.15.10 460 718 1.3E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 SUPERFAMILY SSF55785 251 366 1.5E-12 T 28-03-2018 IPR000014 PAS domain CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 SUPERFAMILY SSF55874 430 599 4.06E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 Gene3D G3DSA:1.10.287.130 371 437 7.9E-19 T 28-03-2018 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 Pfam PF00512 His Kinase A (phospho-acceptor) domain 375 440 3.5E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 SUPERFAMILY SSF158472 203 252 4.45E-10 T 28-03-2018 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 SMART SM00091 262 327 3.9E-8 T 28-03-2018 IPR000014 PAS domain CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 SMART SM00387 485 599 2.7E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 SUPERFAMILY SSF103190 56 179 3.49E-7 T 28-03-2018 IPR029151 Periplasmic sensor domain-like CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 597 3.5E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 260 374 6.2E-12 T 28-03-2018 IPR000014 PAS domain CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 SMART SM00304 203 255 1.4E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 Pfam PF00989 PAS fold 263 365 2.1E-8 T 28-03-2018 IPR013767 PAS fold GO:0006355 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 538 6.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 559 577 6.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 552 6.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 583 596 6.0E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 Gene3D G3DSA:3.30.450.20 248 370 9.1E-22 T 28-03-2018 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 SUPERFAMILY SSF47384 359 440 2.75E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 Pfam PF00672 HAMP domain 203 251 2.8E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 SMART SM00388 374 441 1.2E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 Gene3D G3DSA:3.30.565.10 448 599 1.8E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04350 9c8401327ed88121ab5e61e83313b58d 608 Gene3D G3DSA:3.30.450.20 33 181 7.3E-11 T 28-03-2018 CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 SUPERFAMILY SSF52096 72 148 3.15E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 SUPERFAMILY SSF52096 219 394 3.15E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 Pfam PF13180 PDZ domain 131 209 5.6E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 Gene3D G3DSA:1.10.101.10 400 478 5.9E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 Gene3D G3DSA:3.90.226.10 210 399 1.3E-55 T 28-03-2018 CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 82 395 4.0E-103 T 28-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 Pfam PF03572 Peptidase family S41 225 388 4.0E-48 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 SMART SM00228 130 201 1.6E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 SUPERFAMILY SSF47090 400 471 1.31E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 Gene3D G3DSA:2.30.42.10 130 209 4.4E-22 T 28-03-2018 CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 Pfam PF01471 Putative peptidoglycan binding domain 415 464 9.7E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 SMART SM00245 201 390 4.2E-59 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 SUPERFAMILY SSF50156 101 215 2.93E-22 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS10095 91b3808bb4891ccf09a2ef442b605832 490 Gene3D G3DSA:3.30.750.44 50 129 3.2E-17 T 28-03-2018 CWR44_RS00190 fd005d2696c95210cfbc80fb219924c9 209 SUPERFAMILY SSF53271 4 207 5.64E-73 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWR44_RS00190 fd005d2696c95210cfbc80fb219924c9 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 4.4E-76 T 28-03-2018 CWR44_RS00190 fd005d2696c95210cfbc80fb219924c9 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 5.5E-92 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CWR44_RS00190 fd005d2696c95210cfbc80fb219924c9 209 Gene3D G3DSA:3.40.50.2020 2 207 4.2E-66 T 28-03-2018 CWR44_RS00190 fd005d2696c95210cfbc80fb219924c9 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.918 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CWR44_RS10895 296296a3dc1f175ebb1c392ca6f085a3 96 Gene3D G3DSA:3.30.110.60 1 96 8.2E-30 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWR44_RS10895 296296a3dc1f175ebb1c392ca6f085a3 96 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 9.5E-25 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWR44_RS10895 296296a3dc1f175ebb1c392ca6f085a3 96 SUPERFAMILY SSF75471 1 93 1.83E-31 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWR44_RS10895 296296a3dc1f175ebb1c392ca6f085a3 96 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 3.0E-45 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWR44_RS10895 296296a3dc1f175ebb1c392ca6f085a3 96 SMART SM01103 2 85 3.3E-43 T 28-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CWR44_RS10895 296296a3dc1f175ebb1c392ca6f085a3 96 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 3.8E-35 T 28-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 556 605 1.7E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 661 706 2.5E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 713 755 6.4E-13 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 764 808 1.8E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 614 657 4.6E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 507 550 2.5E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 SMART SM00434 12 466 1.0E-293 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 6 812 24.901 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 9 811 0.0 T 28-03-2018 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Gene3D G3DSA:1.10.268.10 346 488 1.8E-52 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 SUPERFAMILY SSF56719 31 488 4.19E-180 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 473 1.6E-160 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Gene3D G3DSA:3.30.1360.40 237 334 6.5E-36 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Gene3D G3DSA:3.90.199.10 35 216 2.6E-85 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 SUPERFAMILY SSF101904 501 822 3.27E-109 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CWR44_RS04420 f143f16f25ee64fd6a73d8e8cb647ed6 899 Gene3D G3DSA:2.120.10.90 499 812 5.3E-125 T 28-03-2018 CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 Pfam PF01493 GXGXG motif 1239 1423 7.9E-65 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 Gene3D G3DSA:3.20.20.70 778 1212 2.7E-152 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 Pfam PF04898 Glutamate synthase central domain 457 740 7.7E-98 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 SUPERFAMILY SSF56235 20 431 1.26E-127 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 SUPERFAMILY SSF51395 451 1194 2.7E-235 T 28-03-2018 CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 Gene3D G3DSA:3.60.20.10 20 436 1.5E-131 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 SUPERFAMILY SSF69336 1217 1470 6.8E-77 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 Pfam PF01645 Conserved region in glutamate synthase 794 1160 3.7E-154 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 Pfam PF00310 Glutamine amidotransferases class-II 20 429 5.5E-157 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 Gene3D G3DSA:3.20.20.70 437 777 1.5E-77 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS05160 80fda9ed075fe7c815bb092df23c0ca1 1506 Gene3D G3DSA:2.160.20.60 1214 1483 7.2E-88 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CWR44_RS08015 b04848e19ce2dbcf969820c151756e12 364 SUPERFAMILY SSF52540 4 244 6.92E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08015 b04848e19ce2dbcf969820c151756e12 364 Pfam PF00005 ABC transporter 20 161 9.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS08015 b04848e19ce2dbcf969820c151756e12 364 Gene3D G3DSA:2.40.50.100 242 290 0.15 T 28-03-2018 CWR44_RS08015 b04848e19ce2dbcf969820c151756e12 364 Pfam PF08402 TOBE domain 273 341 3.0E-8 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CWR44_RS08015 b04848e19ce2dbcf969820c151756e12 364 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS08015 b04848e19ce2dbcf969820c151756e12 364 Gene3D G3DSA:3.40.50.300 1 241 6.4E-72 T 28-03-2018 CWR44_RS08015 b04848e19ce2dbcf969820c151756e12 364 SUPERFAMILY SSF50331 237 342 8.08E-14 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CWR44_RS08015 b04848e19ce2dbcf969820c151756e12 364 SMART SM00382 29 212 5.5E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS12675 6e3f41e3e49c136d544ebcd8b1b49815 414 Pfam PF00909 Ammonium Transporter Family 8 402 1.2E-115 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CWR44_RS12675 6e3f41e3e49c136d544ebcd8b1b49815 414 TIGRFAM TIGR00836 amt: ammonium transporter 5 402 9.0E-126 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CWR44_RS12675 6e3f41e3e49c136d544ebcd8b1b49815 414 SUPERFAMILY SSF111352 4 380 4.18E-117 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CWR44_RS12675 6e3f41e3e49c136d544ebcd8b1b49815 414 Gene3D G3DSA:1.10.3430.10 1 382 2.0E-123 T 28-03-2018 CWR44_RS01215 91cb07206182e4318099aa22f68e191c 403 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 1 401 22.278 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CWR44_RS01215 91cb07206182e4318099aa22f68e191c 403 Pfam PF03616 Sodium/glutamate symporter 2 369 3.8E-140 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CWR44_RS01215 91cb07206182e4318099aa22f68e191c 403 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 2 400 2.3E-107 T 28-03-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 CWR44_RS06460 842e00fc37389d0d0748b60e73492421 553 Pfam PF00005 ABC transporter 345 484 1.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06460 842e00fc37389d0d0748b60e73492421 553 SUPERFAMILY SSF90123 12 314 2.09E-35 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR44_RS06460 842e00fc37389d0d0748b60e73492421 553 Gene3D G3DSA:1.20.1560.10 4 311 3.8E-21 T 28-03-2018 CWR44_RS06460 842e00fc37389d0d0748b60e73492421 553 SUPERFAMILY SSF52540 319 543 2.79E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06460 842e00fc37389d0d0748b60e73492421 553 SMART SM00382 354 529 2.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS06460 842e00fc37389d0d0748b60e73492421 553 Pfam PF00664 ABC transporter transmembrane region 13 282 4.6E-12 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR44_RS06460 842e00fc37389d0d0748b60e73492421 553 Gene3D G3DSA:3.40.50.300 312 553 3.2E-57 T 28-03-2018 CWR44_RS12730 0ba232ba610f7d9dae25dd5f4529955c 80 Gene3D G3DSA:3.30.70.260 2 80 1.1E-14 T 28-03-2018 CWR44_RS12730 0ba232ba610f7d9dae25dd5f4529955c 80 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 1.0E-29 T 28-03-2018 CWR44_RS12730 0ba232ba610f7d9dae25dd5f4529955c 80 SUPERFAMILY SSF55021 2 78 1.68E-12 T 28-03-2018 CWR44_RS12730 0ba232ba610f7d9dae25dd5f4529955c 80 Pfam PF13291 ACT domain 5 75 1.5E-7 T 28-03-2018 IPR002912 ACT domain CWR44_RS00770 a73b1b69956f0c336aa48b30b729b57b 117 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.411 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00770 a73b1b69956f0c336aa48b30b729b57b 117 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00770 a73b1b69956f0c336aa48b30b729b57b 117 Gene3D G3DSA:3.90.470.10 1 117 6.5E-43 T 28-03-2018 CWR44_RS00770 a73b1b69956f0c336aa48b30b729b57b 117 SUPERFAMILY SSF54843 1 111 4.06E-43 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00770 a73b1b69956f0c336aa48b30b729b57b 117 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 1.6E-35 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00770 a73b1b69956f0c336aa48b30b729b57b 117 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 4.3E-47 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS12915 42dfcee18d489658e9e5d4ce02328265 291 Pfam PF02096 60Kd inner membrane protein 56 248 3.3E-45 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWR44_RS12915 42dfcee18d489658e9e5d4ce02328265 291 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 252 29.428 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CWR44_RS12915 42dfcee18d489658e9e5d4ce02328265 291 PRINTS PR00701 60kDa inner membrane protein signature 215 238 1.4E-5 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWR44_RS12915 42dfcee18d489658e9e5d4ce02328265 291 PRINTS PR00701 60kDa inner membrane protein signature 129 152 1.4E-5 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWR44_RS12915 42dfcee18d489658e9e5d4ce02328265 291 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 56 248 4.7E-48 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CWR44_RS00085 42dfcee18d489658e9e5d4ce02328265 291 Pfam PF02096 60Kd inner membrane protein 56 248 3.3E-45 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWR44_RS00085 42dfcee18d489658e9e5d4ce02328265 291 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 252 29.428 T 28-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CWR44_RS00085 42dfcee18d489658e9e5d4ce02328265 291 PRINTS PR00701 60kDa inner membrane protein signature 215 238 1.4E-5 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWR44_RS00085 42dfcee18d489658e9e5d4ce02328265 291 PRINTS PR00701 60kDa inner membrane protein signature 129 152 1.4E-5 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWR44_RS00085 42dfcee18d489658e9e5d4ce02328265 291 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 56 248 4.7E-48 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 491 1.2E-171 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 519 50.496 T 28-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 Gene3D G3DSA:1.10.730.10 356 524 1.4E-40 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 Pfam PF08264 Anticodon-binding domain of tRNA 396 535 5.4E-9 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 SUPERFAMILY SSF50249 559 656 2.11E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 267 282 3.8E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 359 370 3.8E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 3.8E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 3.8E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 3.8E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 PRINTS PR01041 Methionyl-tRNA synthetase signature 234 245 3.8E-31 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 SUPERFAMILY SSF52374 3 362 2.39E-111 T 28-03-2018 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 Gene3D G3DSA:2.40.50.140 551 659 8.7E-29 T 28-03-2018 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 Pfam PF01588 Putative tRNA binding domain 566 656 3.3E-26 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 Pfam PF09334 tRNA synthetases class I (M) 6 371 1.1E-115 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 Gene3D G3DSA:3.40.50.620 3 355 2.9E-100 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 535 658 3.7E-42 T 28-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CWR44_RS05280 c3604e3017baba4d85dc08e35cec6cf1 659 SUPERFAMILY SSF47323 361 572 2.06E-43 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS09480 821bc56179dd149ff430c177fd6b514c 127 Gene3D G3DSA:1.10.8.200 4 65 5.5E-12 T 28-03-2018 CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 SUPERFAMILY SSF64307 108 188 1.96E-18 T 28-03-2018 IPR001455 TusA-like domain CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 SMART SM00450 10 102 8.9E-19 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 Pfam PF00581 Rhodanese-like domain 15 98 7.4E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 SUPERFAMILY SSF52821 15 102 3.01E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 Pfam PF13686 DsrE/DsrF/DrsH-like family 202 354 1.4E-54 T 28-03-2018 IPR032836 DsrE2-like family CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 Gene3D G3DSA:3.40.1260.10 194 355 2.0E-50 T 28-03-2018 CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 SUPERFAMILY SSF75169 297 350 8.51E-20 T 28-03-2018 IPR027396 DsrEFH-like CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 SUPERFAMILY SSF75169 203 247 8.51E-20 T 28-03-2018 IPR027396 DsrEFH-like CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 Gene3D G3DSA:3.40.250.10 4 102 1.4E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 Pfam PF01206 Sulfurtransferase TusA 120 188 1.6E-15 T 28-03-2018 IPR001455 TusA-like domain CWR44_RS04140 4b62226be4fb77b88ee2107baf28364f 355 Gene3D G3DSA:3.30.110.40 103 189 2.4E-22 T 28-03-2018 IPR001455 TusA-like domain CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PIRSF PIRSF000350 1 440 2.8E-59 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 300 3.6E-24 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.6E-24 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 3.6E-24 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 3.6E-24 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 3.6E-24 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 312 1.8E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 335 435 2.3E-13 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 SUPERFAMILY SSF51905 1 354 1.94E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 Gene3D G3DSA:3.40.50.720 167 323 2.1E-28 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 SUPERFAMILY SSF55424 332 442 4.98E-21 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.9E-42 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 3.9E-42 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 331 352 3.9E-42 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 293 300 3.9E-42 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 3.9E-42 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 394 409 3.9E-42 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 416 436 3.9E-42 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 3.9E-42 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 3.9E-42 T 28-03-2018 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 Gene3D G3DSA:3.50.50.60 1 166 7.8E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03505 4d2bb96cd7f291ee03a1945c26de06ea 447 Gene3D G3DSA:3.30.390.30 324 445 1.4E-18 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS10680 0fb60f1155321d3db3f019e65d2dac59 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.517 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10680 0fb60f1155321d3db3f019e65d2dac59 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 2.0E-20 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10680 0fb60f1155321d3db3f019e65d2dac59 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS10680 0fb60f1155321d3db3f019e65d2dac59 49 Pfam PF00471 Ribosomal protein L33 3 49 3.8E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10680 0fb60f1155321d3db3f019e65d2dac59 49 SUPERFAMILY SSF57829 1 49 6.71E-19 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CWR44_RS05240 27622323c0b0e6c3516f1337ec52f7f6 203 ProSitePatterns PS01331 Thymidylate kinase signature. 89 101 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWR44_RS05240 27622323c0b0e6c3516f1337ec52f7f6 203 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 192 7.9E-56 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWR44_RS05240 27622323c0b0e6c3516f1337ec52f7f6 203 Gene3D G3DSA:3.40.50.300 2 198 7.1E-53 T 28-03-2018 CWR44_RS05240 27622323c0b0e6c3516f1337ec52f7f6 203 Hamap MF_00165 Thymidylate kinase [tmk]. 3 202 30.743 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWR44_RS05240 27622323c0b0e6c3516f1337ec52f7f6 203 SUPERFAMILY SSF52540 2 202 1.24E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05240 27622323c0b0e6c3516f1337ec52f7f6 203 Pfam PF02223 Thymidylate kinase 7 193 1.4E-50 T 28-03-2018 CWR44_RS06600 0be71b919877c6af90fb9e4f3292ed4e 238 Gene3D G3DSA:2.40.100.10 96 230 9.3E-32 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS06600 0be71b919877c6af90fb9e4f3292ed4e 238 SUPERFAMILY SSF160467 2 102 4.58E-12 T 28-03-2018 CWR44_RS06600 0be71b919877c6af90fb9e4f3292ed4e 238 SUPERFAMILY SSF50891 99 227 1.29E-33 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS06600 0be71b919877c6af90fb9e4f3292ed4e 238 SMART SM00796 1 212 3.1E-70 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CWR44_RS06600 0be71b919877c6af90fb9e4f3292ed4e 238 Gene3D G3DSA:3.30.1360.40 1 92 1.4E-7 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWR44_RS06600 0be71b919877c6af90fb9e4f3292ed4e 238 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 212 2.4E-43 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CWR44_RS01840 e4a001647e5997d84d1964dab23cff3b 514 Pfam PF03806 AbgT putative transporter family 14 510 2.8E-205 T 28-03-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 CWR44_RS11145 e6c001f70922c7e138bc5246e65f2031 278 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 10 270 1.7E-41 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CWR44_RS11145 e6c001f70922c7e138bc5246e65f2031 278 PIRSF PIRSF038471 1 278 1.2E-55 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CWR44_RS11145 e6c001f70922c7e138bc5246e65f2031 278 Pfam PF04085 rod shape-determining protein MreC 113 264 2.2E-39 T 28-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CWR44_RS11145 e6c001f70922c7e138bc5246e65f2031 278 Gene3D G3DSA:1.20.5.170 70 102 0.0017 T 28-03-2018 CWR44_RS11145 e6c001f70922c7e138bc5246e65f2031 278 Gene3D G3DSA:2.40.50.140 129 217 0.26 T 28-03-2018 CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 Gene3D G3DSA:1.10.580.10 294 352 8.2E-10 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 Pfam PF00285 Citrate synthase, C-terminal domain 7 355 7.2E-127 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 ProSitePatterns PS00480 Citrate synthase signature. 255 267 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 PIRSF PIRSF001369 1 372 3.7E-147 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 SUPERFAMILY SSF48256 5 372 7.2E-131 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 Gene3D G3DSA:1.10.580.10 12 261 4.7E-83 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 PRINTS PR00143 Citrate synthase signature 173 188 1.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 PRINTS PR00143 Citrate synthase signature 124 137 1.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 PRINTS PR00143 Citrate synthase signature 325 339 1.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 PRINTS PR00143 Citrate synthase signature 305 321 1.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 PRINTS PR00143 Citrate synthase signature 195 223 1.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 PRINTS PR00143 Citrate synthase signature 248 268 1.3E-39 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CWR44_RS11335 6a565dbc07f4c4083d35b8f3bff7a597 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 6 372 1.7E-152 T 28-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CWR44_RS01345 0f064fbe5e1e6b77eaa6737574bc93d7 171 Gene3D G3DSA:3.40.630.30 3 170 2.7E-27 T 28-03-2018 CWR44_RS01345 0f064fbe5e1e6b77eaa6737574bc93d7 171 Pfam PF00583 Acetyltransferase (GNAT) family 37 147 2.8E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS01345 0f064fbe5e1e6b77eaa6737574bc93d7 171 SUPERFAMILY SSF55729 10 158 5.85E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS11440 b82633a0ac72efe8fa655e44141856bc 407 SUPERFAMILY SSF52402 174 389 1.28E-50 T 28-03-2018 CWR44_RS11440 b82633a0ac72efe8fa655e44141856bc 407 SUPERFAMILY SSF143437 3 173 8.89E-51 T 28-03-2018 CWR44_RS11440 b82633a0ac72efe8fa655e44141856bc 407 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 371 1.7E-63 T 28-03-2018 IPR020536 Thil, AANH domain GO:0004810 CWR44_RS11440 b82633a0ac72efe8fa655e44141856bc 407 Gene3D G3DSA:3.30.70.1510 5 82 3.3E-24 T 28-03-2018 CWR44_RS11440 b82633a0ac72efe8fa655e44141856bc 407 Gene3D G3DSA:3.30.2300.10 84 163 6.4E-21 T 28-03-2018 CWR44_RS11440 b82633a0ac72efe8fa655e44141856bc 407 Gene3D G3DSA:3.40.50.620 175 403 6.2E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS11440 b82633a0ac72efe8fa655e44141856bc 407 SMART SM00981 75 165 8.3E-24 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CWR44_RS11440 b82633a0ac72efe8fa655e44141856bc 407 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 374 2.1E-125 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CWR44_RS11440 b82633a0ac72efe8fa655e44141856bc 407 Pfam PF02926 THUMP domain 36 163 2.3E-21 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CWR44_RS11440 b82633a0ac72efe8fa655e44141856bc 407 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 407 159.216 T 28-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CWR44_RS10450 f4626af7ab107f720b4d02c558a26c3e 306 Pfam PF12706 Beta-lactamase superfamily domain 50 153 1.1E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS10450 f4626af7ab107f720b4d02c558a26c3e 306 Gene3D G3DSA:3.60.15.10 1 306 2.1E-57 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS10450 f4626af7ab107f720b4d02c558a26c3e 306 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 304 1.4E-103 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CWR44_RS10450 f4626af7ab107f720b4d02c558a26c3e 306 Hamap MF_01818 Ribonuclease BN [rbn]. 1 306 35.957 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CWR44_RS10450 f4626af7ab107f720b4d02c558a26c3e 306 SUPERFAMILY SSF56281 1 305 6.16E-73 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS00330 cabb97b12afde3b27710287c3d4944c3 147 Pfam PF00210 Ferritin-like domain 9 146 3.7E-33 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CWR44_RS00330 cabb97b12afde3b27710287c3d4944c3 147 ProSitePatterns PS00819 Dps protein family signature 2. 55 69 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CWR44_RS00330 cabb97b12afde3b27710287c3d4944c3 147 PIRSF PIRSF005900 2 147 2.7E-50 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CWR44_RS00330 cabb97b12afde3b27710287c3d4944c3 147 ProSitePatterns PS00818 Dps protein family signature 1. 29 45 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CWR44_RS00330 cabb97b12afde3b27710287c3d4944c3 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 53 69 6.8E-15 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CWR44_RS00330 cabb97b12afde3b27710287c3d4944c3 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 124 142 6.8E-15 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CWR44_RS00330 cabb97b12afde3b27710287c3d4944c3 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 29 45 6.8E-15 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CWR44_RS00330 cabb97b12afde3b27710287c3d4944c3 147 Gene3D G3DSA:1.20.1260.10 2 147 3.7E-46 T 28-03-2018 IPR012347 Ferritin-related CWR44_RS00330 cabb97b12afde3b27710287c3d4944c3 147 SUPERFAMILY SSF47240 5 146 6.69E-46 T 28-03-2018 IPR009078 Ferritin-like superfamily CWR44_RS10780 983852a3fd68b554f437ce432f3fd77d 315 Pfam PF02562 PhoH-like protein 109 312 3.5E-94 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CWR44_RS10780 983852a3fd68b554f437ce432f3fd77d 315 Gene3D G3DSA:3.40.50.300 106 312 1.0E-30 T 28-03-2018 CWR44_RS10780 983852a3fd68b554f437ce432f3fd77d 315 SUPERFAMILY SSF54791 11 75 1.0E-4 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR44_RS10780 983852a3fd68b554f437ce432f3fd77d 315 SUPERFAMILY SSF52540 63 287 3.17E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07455 e1fdda69d4cf50d28f0cb38e35f76190 313 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 184 6.1E-29 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWR44_RS07455 e1fdda69d4cf50d28f0cb38e35f76190 313 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 311 69.596 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWR44_RS07455 e1fdda69d4cf50d28f0cb38e35f76190 313 Gene3D G3DSA:3.40.47.10 161 310 7.1E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS07455 e1fdda69d4cf50d28f0cb38e35f76190 313 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 311 1.1E-125 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWR44_RS07455 e1fdda69d4cf50d28f0cb38e35f76190 313 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 311 1.6E-35 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CWR44_RS07455 e1fdda69d4cf50d28f0cb38e35f76190 313 SUPERFAMILY SSF53901 3 311 5.22E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS07455 e1fdda69d4cf50d28f0cb38e35f76190 313 Gene3D G3DSA:3.40.47.10 1 160 1.5E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS03515 82d70ff7b4cd868c76e9e1a9bccb8678 357 SMART SM00829 15 345 9.2E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR44_RS03515 82d70ff7b4cd868c76e9e1a9bccb8678 357 SUPERFAMILY SSF51735 148 305 2.45E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS03515 82d70ff7b4cd868c76e9e1a9bccb8678 357 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 142 7.2E-35 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWR44_RS03515 82d70ff7b4cd868c76e9e1a9bccb8678 357 SUPERFAMILY SSF50129 9 180 9.43E-61 T 28-03-2018 IPR011032 GroES-like CWR44_RS03515 82d70ff7b4cd868c76e9e1a9bccb8678 357 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CWR44_RS03515 82d70ff7b4cd868c76e9e1a9bccb8678 357 Pfam PF00107 Zinc-binding dehydrogenase 183 310 2.5E-33 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR44_RS03515 82d70ff7b4cd868c76e9e1a9bccb8678 357 Gene3D G3DSA:3.90.180.10 5 175 1.5E-55 T 28-03-2018 CWR44_RS03515 82d70ff7b4cd868c76e9e1a9bccb8678 357 Gene3D G3DSA:3.40.50.720 176 296 6.6E-29 T 28-03-2018 CWR44_RS08045 2dc4ab4b18df566e0c0a994f0e14622e 446 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 22 443 38.968 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS08045 2dc4ab4b18df566e0c0a994f0e14622e 446 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 30 411 8.3E-113 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS08045 2dc4ab4b18df566e0c0a994f0e14622e 446 Pfam PF01566 Natural resistance-associated macrophage protein 51 418 1.8E-119 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS08045 2dc4ab4b18df566e0c0a994f0e14622e 446 PRINTS PR00447 Natural resistance-associated macrophage protein signature 138 157 1.1E-64 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS08045 2dc4ab4b18df566e0c0a994f0e14622e 446 PRINTS PR00447 Natural resistance-associated macrophage protein signature 353 370 1.1E-64 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS08045 2dc4ab4b18df566e0c0a994f0e14622e 446 PRINTS PR00447 Natural resistance-associated macrophage protein signature 110 136 1.1E-64 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS08045 2dc4ab4b18df566e0c0a994f0e14622e 446 PRINTS PR00447 Natural resistance-associated macrophage protein signature 215 238 1.1E-64 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS08045 2dc4ab4b18df566e0c0a994f0e14622e 446 PRINTS PR00447 Natural resistance-associated macrophage protein signature 387 406 1.1E-64 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS08045 2dc4ab4b18df566e0c0a994f0e14622e 446 PRINTS PR00447 Natural resistance-associated macrophage protein signature 163 184 1.1E-64 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS08045 2dc4ab4b18df566e0c0a994f0e14622e 446 PRINTS PR00447 Natural resistance-associated macrophage protein signature 325 344 1.1E-64 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS03190 9f4bcd49fe389f48186788a8a3d1521e 257 SMART SM00382 39 222 8.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03190 9f4bcd49fe389f48186788a8a3d1521e 257 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS03190 9f4bcd49fe389f48186788a8a3d1521e 257 SUPERFAMILY SSF52540 9 247 1.87E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03190 9f4bcd49fe389f48186788a8a3d1521e 257 Pfam PF00005 ABC transporter 30 173 1.2E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS03190 9f4bcd49fe389f48186788a8a3d1521e 257 Gene3D G3DSA:3.40.50.300 11 253 2.5E-48 T 28-03-2018 CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 SUPERFAMILY SSF48557 3 458 7.54E-149 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 Gene3D G3DSA:1.10.40.30 416 460 4.1E-27 T 28-03-2018 CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 Pfam PF10415 Fumarase C C-terminus 406 458 2.6E-26 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 1.4E-6 T 28-03-2018 CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 PRINTS PR00145 Argininosuccinate lyase family signature 131 153 1.4E-6 T 28-03-2018 CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 PRINTS PR00145 Argininosuccinate lyase family signature 173 193 1.4E-6 T 28-03-2018 CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 1.0E-34 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 1.0E-34 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 1.0E-34 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 1.0E-34 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 460 88.915 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 Pfam PF00206 Lyase 11 340 5.7E-111 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 Gene3D G3DSA:1.20.200.10 137 415 1.8E-86 T 28-03-2018 CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 Gene3D G3DSA:1.10.275.10 1 136 4.8E-56 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CWR44_RS11980 f57b96c14ea9e9d89c785dae82ea6e0b 461 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 458 1.4E-225 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CWR44_RS00625 e5482ac30b738c8bf05d2b6181fe5c8f 243 SUPERFAMILY SSF52467 2 242 5.54E-80 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS00625 e5482ac30b738c8bf05d2b6181fe5c8f 243 Gene3D G3DSA:3.40.50.1220 1 243 1.6E-62 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS00625 e5482ac30b738c8bf05d2b6181fe5c8f 243 Pfam PF02146 Sir2 family 23 198 1.6E-53 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CWR44_RS00625 e5482ac30b738c8bf05d2b6181fe5c8f 243 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 7 241 61.122 T 28-03-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 CWR44_RS06115 9ae5c3fa95ecd3e3e2fc2f47317d5d63 124 SUPERFAMILY SSF46785 6 113 7.44E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06115 9ae5c3fa95ecd3e3e2fc2f47317d5d63 124 TIGRFAM TIGR01889 Staph_reg_Sar: staphylococcal accessory regulator family 11 116 2.5E-34 T 28-03-2018 IPR010166 Transcriptional regulator SarA/Rot GO:0006355 CWR44_RS06115 9ae5c3fa95ecd3e3e2fc2f47317d5d63 124 Gene3D G3DSA:1.10.10.10 2 124 6.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10570 abf02891e0dfc7771d3ef4727ee8432f 352 Gene3D G3DSA:3.90.230.10 126 352 3.3E-81 T 28-03-2018 CWR44_RS10570 abf02891e0dfc7771d3ef4727ee8432f 352 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 126 3.1E-21 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CWR44_RS10570 abf02891e0dfc7771d3ef4727ee8432f 352 SUPERFAMILY SSF53092 8 126 1.1E-23 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWR44_RS10570 abf02891e0dfc7771d3ef4727ee8432f 352 Gene3D G3DSA:3.40.350.10 1 124 2.0E-24 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWR44_RS10570 abf02891e0dfc7771d3ef4727ee8432f 352 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 282 294 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CWR44_RS10570 abf02891e0dfc7771d3ef4727ee8432f 352 Pfam PF00557 Metallopeptidase family M24 133 336 4.2E-65 T 28-03-2018 IPR000994 Peptidase M24 CWR44_RS10570 abf02891e0dfc7771d3ef4727ee8432f 352 SUPERFAMILY SSF55920 83 347 1.57E-81 T 28-03-2018 IPR000994 Peptidase M24 CWR44_RS04855 bdfe3fdce6ef5ed7852a7351e8505be4 192 SUPERFAMILY SSF53254 1 191 8.16E-46 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWR44_RS04855 bdfe3fdce6ef5ed7852a7351e8505be4 192 SMART SM00855 2 165 5.6E-15 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWR44_RS04855 bdfe3fdce6ef5ed7852a7351e8505be4 192 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CWR44_RS04855 bdfe3fdce6ef5ed7852a7351e8505be4 192 Gene3D G3DSA:3.40.50.1240 1 192 8.0E-45 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CWR44_RS04855 bdfe3fdce6ef5ed7852a7351e8505be4 192 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 187 2.1E-38 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CWR44_RS04855 bdfe3fdce6ef5ed7852a7351e8505be4 192 PIRSF PIRSF000709 1 184 1.4E-20 T 28-03-2018 CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 Gene3D G3DSA:3.40.50.300 1 255 1.9E-13 T 28-03-2018 CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 Gene3D G3DSA:3.40.50.300 716 971 2.9E-10 T 28-03-2018 CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 Gene3D G3DSA:1.20.120.330 508 715 5.2E-4 T 28-03-2018 CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 SUPERFAMILY SSF52540 1 149 4.35E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 SUPERFAMILY SSF52540 880 969 4.35E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 SUPERFAMILY SSF52540 204 212 4.35E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 SUPERFAMILY SSF52540 666 702 2.28E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 SUPERFAMILY SSF52540 487 569 2.28E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 SUPERFAMILY SSF52540 788 958 2.28E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 Gene3D G3DSA:1.10.287.510 256 358 0.045 T 28-03-2018 CWR44_RS11940 713d1883c679d13b1b407c46bd299f74 978 Pfam PF13514 AAA domain 1 206 6.0E-21 T 28-03-2018 CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 Gene3D G3DSA:3.90.1150.10 294 396 2.5E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 SUPERFAMILY SSF53383 2 395 3.99E-127 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 4 395 8.9E-163 T 28-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 Gene3D G3DSA:3.40.640.10 170 293 8.7E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 Hamap MF_01689 Ornithine aminotransferase [rocD]. 4 396 67.039 T 28-03-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 PIRSF PIRSF000521 1 159 2.5E-10 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 PIRSF PIRSF000521 171 396 2.2E-34 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 12 396 38.012 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 Gene3D G3DSA:3.90.1150.10 1 169 1.2E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS07355 15d7d67e788a47508b645c1ef275fba0 396 Pfam PF00202 Aminotransferase class-III 15 394 1.4E-132 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS10800 edd9666bb5d02197589f136531470243 58 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 5.3E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10800 edd9666bb5d02197589f136531470243 58 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 5.3E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10800 edd9666bb5d02197589f136531470243 58 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 5.3E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10800 edd9666bb5d02197589f136531470243 58 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 5.3E-16 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10800 edd9666bb5d02197589f136531470243 58 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 28-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS10800 edd9666bb5d02197589f136531470243 58 Gene3D G3DSA:1.20.5.1150 16 52 7.1E-19 T 28-03-2018 CWR44_RS10800 edd9666bb5d02197589f136531470243 58 Pfam PF01165 Ribosomal protein S21 5 57 5.9E-22 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10800 edd9666bb5d02197589f136531470243 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 58 1.1E-21 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10800 edd9666bb5d02197589f136531470243 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 1.0E-8 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10800 edd9666bb5d02197589f136531470243 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.847 T 28-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 Gene3D G3DSA:3.40.50.10090 1 42 1.2E-8 T 28-03-2018 CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.5E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.5E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.5E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.5E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 4.5E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.5E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 6 244 4.3E-107 T 28-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 SUPERFAMILY SSF51735 3 245 3.14E-92 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 Gene3D G3DSA:3.40.50.720 43 245 1.0E-71 T 28-03-2018 CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.0E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.0E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.0E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 243 7.7E-71 T 28-03-2018 CWR44_RS08565 268bc564e0e747a06dbc26224b2fc2c1 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 184 1.4E-5 T 28-03-2018 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 SUPERFAMILY SSF54752 268 326 2.62E-22 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 SMART SM00382 57 228 8.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 Pfam PF00154 recA bacterial DNA recombination protein 7 268 3.0E-143 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 SUPERFAMILY SSF52540 3 267 3.35E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 PRINTS PR00142 RecA protein signature 93 122 3.3E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 PRINTS PR00142 RecA protein signature 127 156 3.3E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 PRINTS PR00142 RecA protein signature 243 272 3.3E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 PRINTS PR00142 RecA protein signature 165 194 3.3E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 PRINTS PR00142 RecA protein signature 297 314 3.3E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 PRINTS PR00142 RecA protein signature 210 238 3.3E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 7.2E-172 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 Hamap MF_00268 Protein RecA [recA]. 5 329 53.229 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 Gene3D G3DSA:3.40.50.300 26 268 1.2E-46 T 28-03-2018 CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 Gene3D G3DSA:3.30.250.10 269 326 1.1E-26 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CWR44_RS08835 3f7964bd987043dbea15f7de4d4d5680 348 ProSitePatterns PS00321 recA signature. 213 221 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CWR44_RS02970 26698caff0cf8f6925b3f7b25aaf4269 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 220 1.8E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS02970 26698caff0cf8f6925b3f7b25aaf4269 223 SUPERFAMILY SSF52172 6 172 1.42E-29 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS02970 26698caff0cf8f6925b3f7b25aaf4269 223 Pfam PF00072 Response regulator receiver domain 11 117 5.2E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS02970 26698caff0cf8f6925b3f7b25aaf4269 223 Gene3D G3DSA:3.40.50.2300 3 130 5.6E-28 T 28-03-2018 CWR44_RS02970 26698caff0cf8f6925b3f7b25aaf4269 223 SMART SM00862 148 220 6.5E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS02970 26698caff0cf8f6925b3f7b25aaf4269 223 Gene3D G3DSA:1.10.10.10 131 222 1.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02970 26698caff0cf8f6925b3f7b25aaf4269 223 SMART SM00448 9 116 3.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS07180 74793255d71734d494226a7fc3bb675d 275 Pfam PF01925 Sulfite exporter TauE/SafE 9 269 1.6E-53 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CWR44_RS07180 74793255d71734d494226a7fc3bb675d 275 Gene3D G3DSA:1.20.1250.20 67 271 3.7E-4 T 28-03-2018 CWR44_RS09135 7da3bf5855fa78ac125b8d6343e4f67a 384 Gene3D G3DSA:3.30.2320.10 251 349 8.0E-5 T 28-03-2018 CWR44_RS09135 7da3bf5855fa78ac125b8d6343e4f67a 384 SUPERFAMILY SSF56563 120 379 1.44E-26 T 28-03-2018 CWR44_RS09135 7da3bf5855fa78ac125b8d6343e4f67a 384 Pfam PF05065 Phage capsid family 130 378 1.4E-11 T 28-03-2018 IPR024455 Phage capsid CWR44_RS09135 7da3bf5855fa78ac125b8d6343e4f67a 384 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 16 379 2.4E-22 T 28-03-2018 IPR024455 Phage capsid CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 Pfam PF00334 Nucleoside diphosphate kinase 2 135 4.0E-57 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 Gene3D G3DSA:3.30.70.141 1 149 1.9E-60 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 36.374 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 SUPERFAMILY SSF54919 1 149 1.03E-59 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 SMART SM00562 1 138 1.3E-88 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 2.4E-46 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 2.4E-46 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 2.4E-46 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 2.4E-46 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS10305 a04c9b85d4dfa3f3b8ca762757104e9e 149 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 2.4E-46 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS03115 18dd39f7b5532ef861de458f16198298 195 SUPERFAMILY SSF46689 6 72 1.09E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS03115 18dd39f7b5532ef861de458f16198298 195 Gene3D G3DSA:1.10.10.60 49 172 3.1E-8 T 28-03-2018 CWR44_RS03115 18dd39f7b5532ef861de458f16198298 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 60 1.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS03115 18dd39f7b5532ef861de458f16198298 195 Gene3D G3DSA:1.10.10.60 3 48 3.8E-14 T 28-03-2018 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 SUPERFAMILY SSF54680 332 431 1.2E-27 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 Gene3D G3DSA:3.40.1030.10 68 337 1.3E-96 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 SMART SM00941 345 418 2.6E-31 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 Gene3D G3DSA:3.90.1170.30 338 423 2.1E-27 T 28-03-2018 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 Gene3D G3DSA:1.20.970.10 1 66 1.1E-26 T 28-03-2018 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 5.5E-183 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 SUPERFAMILY SSF52418 69 328 4.45E-95 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 SUPERFAMILY SSF47648 1 69 4.71E-23 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 1.4E-23 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 PIRSF PIRSF000478 1 432 1.3E-169 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 417 1.2E-27 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00315 f01b164c7b0e4f239832fe2b9ffdc3b0 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 5.5E-49 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS05685 c218c025298e5b42ed335ebdb03c32c9 139 SUPERFAMILY SSF55811 5 120 7.99E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR44_RS05685 c218c025298e5b42ed335ebdb03c32c9 139 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWR44_RS05685 c218c025298e5b42ed335ebdb03c32c9 139 Gene3D G3DSA:3.90.79.10 1 128 3.0E-26 T 28-03-2018 CWR44_RS05685 c218c025298e5b42ed335ebdb03c32c9 139 Pfam PF00293 NUDIX domain 6 113 6.0E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR44_RS05685 c218c025298e5b42ed335ebdb03c32c9 139 PRINTS PR00502 NUDIX hydrolase family signature 43 58 6.9E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWR44_RS05685 c218c025298e5b42ed335ebdb03c32c9 139 PRINTS PR00502 NUDIX hydrolase family signature 29 43 6.9E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CWR44_RS09865 93ab66039c134b7074cf60bb249f57c9 338 SUPERFAMILY SSF52418 73 329 1.06E-76 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS09865 93ab66039c134b7074cf60bb249f57c9 338 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 328 4.0E-92 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CWR44_RS09865 93ab66039c134b7074cf60bb249f57c9 338 Pfam PF00591 Glycosyl transferase family, a/b domain 76 322 9.8E-78 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS09865 93ab66039c134b7074cf60bb249f57c9 338 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 2 332 32.558 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CWR44_RS09865 93ab66039c134b7074cf60bb249f57c9 338 Gene3D G3DSA:3.40.1030.10 68 331 2.4E-81 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS03425 7889be10d74c026345101d3f73cb6e11 1068 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 301 653 3.2E-47 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CWR44_RS03425 7889be10d74c026345101d3f73cb6e11 1068 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 697 1064 1.4E-113 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CWR44_RS03425 7889be10d74c026345101d3f73cb6e11 1068 Gene3D G3DSA:3.40.50.2000 474 622 3.4E-9 T 28-03-2018 CWR44_RS03425 7889be10d74c026345101d3f73cb6e11 1068 SUPERFAMILY SSF53756 353 655 8.16E-12 T 28-03-2018 CWR44_RS03425 7889be10d74c026345101d3f73cb6e11 1068 SUPERFAMILY SSF53756 789 1063 5.97E-12 T 28-03-2018 CWR44_RS02360 92995810dc3a4f292f6cfb7c556ae213 315 SUPERFAMILY SSF51556 2 310 4.64E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase CWR44_RS02360 92995810dc3a4f292f6cfb7c556ae213 315 Pfam PF04909 Amidohydrolase 4 308 2.0E-26 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR44_RS02360 92995810dc3a4f292f6cfb7c556ae213 315 Gene3D G3DSA:3.20.20.140 1 311 9.2E-43 T 28-03-2018 CWR44_RS00210 ed62a4efd96d26d835d66c4b46ac378a 347 Pfam PF03481 Putative GTP-binding controlling metal-binding 205 338 8.3E-20 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CWR44_RS00210 ed62a4efd96d26d835d66c4b46ac378a 347 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 20 212 2.8E-57 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CWR44_RS00210 ed62a4efd96d26d835d66c4b46ac378a 347 Gene3D G3DSA:3.90.870.10 6 218 5.7E-70 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWR44_RS00210 ed62a4efd96d26d835d66c4b46ac378a 347 PIRSF PIRSF004930 1 344 1.4E-113 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CWR44_RS00210 ed62a4efd96d26d835d66c4b46ac378a 347 Pfam PF01300 Telomere recombination 27 203 5.0E-56 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CWR44_RS00210 ed62a4efd96d26d835d66c4b46ac378a 347 SUPERFAMILY SSF55821 17 208 1.4E-60 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CWR44_RS02995 c864a656ae3453f43cef6cf63dd04d86 180 Pfam PF15432 Accessory Sec secretory system ASP3 18 142 1.0E-39 T 28-03-2018 IPR022259 Accessory Sec system protein Asp3 GO:0015031 CWR44_RS02995 c864a656ae3453f43cef6cf63dd04d86 180 TIGRFAM TIGR03711 acc_sec_asp3: accessory Sec system protein Asp3 8 140 3.6E-55 T 28-03-2018 IPR022259 Accessory Sec system protein Asp3 GO:0015031 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 Pfam PF00403 Heavy-metal-associated domain 77 137 7.3E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 Pfam PF00403 Heavy-metal-associated domain 12 68 4.0E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 496 502 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 74 138 8.6E-15 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 265 777 6.8E-97 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 Gene3D G3DSA:3.30.70.100 72 150 5.0E-24 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 SUPERFAMILY SSF55008 3 71 6.28E-19 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 Gene3D G3DSA:3.30.70.100 1 71 3.9E-19 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 SUPERFAMILY SSF55008 73 141 4.58E-21 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 Pfam PF00702 haloacid dehalogenase-like hydrolase 490 702 7.9E-49 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 206 791 1.9E-190 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 ProSitePatterns PS01047 Heavy-metal-associated domain. 79 108 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 225 790 3.8E-201 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 Gene3D G3DSA:3.40.50.1000 614 752 4.8E-43 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00943 Copper-transporting ATPase signature 665 682 3.3E-17 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00943 Copper-transporting ATPase signature 118 138 3.3E-17 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00943 Copper-transporting ATPase signature 415 429 3.3E-17 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00943 Copper-transporting ATPase signature 89 103 3.3E-17 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00943 Copper-transporting ATPase signature 210 229 3.3E-17 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00943 Copper-transporting ATPase signature 477 492 3.3E-17 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00943 Copper-transporting ATPase signature 262 281 3.3E-17 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 SUPERFAMILY SSF81653 296 392 4.84E-28 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 Gene3D G3DSA:1.20.1110.10 257 507 3.3E-50 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 SUPERFAMILY SSF56784 546 788 8.8E-63 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 SUPERFAMILY SSF56784 492 512 8.8E-63 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 SUPERFAMILY SSF81665 257 296 3.4E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 SUPERFAMILY SSF81665 393 486 3.4E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 SUPERFAMILY SSF81665 737 768 3.4E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 711 723 2.7E-28 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 494 508 2.7E-28 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 613 624 2.7E-28 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 688 707 2.7E-28 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 342 356 2.7E-28 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 635 645 2.7E-28 T 28-03-2018 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 Gene3D G3DSA:3.40.1110.10 508 613 1.4E-33 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR44_RS13170 3b97a910669063b4c6e73b9ec9f83ee9 795 Pfam PF00122 E1-E2 ATPase 293 473 5.5E-58 T 28-03-2018 CWR44_RS07430 86e8a7c4369470f1ceada549c55bea4a 274 Gene3D G3DSA:3.40.50.1000 1 270 1.3E-37 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS07430 86e8a7c4369470f1ceada549c55bea4a 274 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 28-03-2018 CWR44_RS07430 86e8a7c4369470f1ceada549c55bea4a 274 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 262 1.0E-63 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS07430 86e8a7c4369470f1ceada549c55bea4a 274 SUPERFAMILY SSF56784 1 267 4.14E-67 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS07430 86e8a7c4369470f1ceada549c55bea4a 274 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 262 1.9E-62 T 28-03-2018 IPR000150 Cof family GO:0016787 CWR44_RS07430 86e8a7c4369470f1ceada549c55bea4a 274 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 235 1.5E-25 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 SUPERFAMILY SSF50249 61 135 3.6E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 SUPERFAMILY SSF50249 130 229 2.43E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 ProSitePatterns PS01175 Ribonuclease II family signature. 549 573 - T 28-03-2018 IPR022966 Ribonuclease II/R, conserved site CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 Gene3D G3DSA:2.40.50.140 632 775 1.1E-24 T 28-03-2018 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 Gene3D G3DSA:2.40.50.140 133 288 0.0072 T 28-03-2018 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 Hamap MF_01895 Ribonuclease R [rnr]. 22 712 58.25 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 SMART SM00316 630 712 5.4E-16 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 SUPERFAMILY SSF50249 212 630 8.0E-143 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 Pfam PF08206 Ribonuclease B OB domain 151 202 4.5E-10 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 Pfam PF08206 Ribonuclease B OB domain 76 134 4.0E-17 T 28-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 Pfam PF00773 RNB domain 252 580 1.7E-110 T 28-03-2018 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 Gene3D G3DSA:2.40.50.140 59 130 0.096 T 28-03-2018 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 Pfam PF00575 S1 RNA binding domain 631 711 3.3E-16 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 712 3.6E-287 T 28-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 Gene3D G3DSA:1.10.10.10 2 58 2.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 SMART SM00955 252 582 3.9E-168 T 28-03-2018 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 SMART SM00357 142 206 2.5E-4 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 SMART SM00357 75 137 6.6E-5 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 SUPERFAMILY SSF50249 632 711 7.86E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS06965 4133a1343ec48cadaa19361e7be36619 792 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 65 712 2.8E-220 T 28-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CWR44_RS05915 5884e2158c8385e63adac2168bfafc29 255 Pfam PF06738 Putative threonine/serine exporter 17 254 4.2E-62 T 28-03-2018 IPR010619 Putative threonine/serine exporter CWR44_RS12685 f8e1420459facd141be576593cc2091c 365 Pfam PF04143 Sulphur transport 21 332 1.3E-97 T 28-03-2018 IPR007272 Sulphur transport domain CWR44_RS08010 513f7b6c15ef7d77fed6e0f26f31b8a8 179 Pfam PF07883 Cupin domain 106 173 1.7E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CWR44_RS08010 513f7b6c15ef7d77fed6e0f26f31b8a8 179 Gene3D G3DSA:2.60.120.10 74 179 3.4E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWR44_RS08010 513f7b6c15ef7d77fed6e0f26f31b8a8 179 SUPERFAMILY SSF51182 54 176 5.24E-25 T 28-03-2018 IPR011051 RmlC-like cupin domain CWR44_RS08010 513f7b6c15ef7d77fed6e0f26f31b8a8 179 SMART SM00530 6 61 5.4E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS08010 513f7b6c15ef7d77fed6e0f26f31b8a8 179 Gene3D G3DSA:1.10.260.40 1 73 2.6E-21 T 28-03-2018 CWR44_RS08010 513f7b6c15ef7d77fed6e0f26f31b8a8 179 SUPERFAMILY SSF47413 1 64 3.66E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS08010 513f7b6c15ef7d77fed6e0f26f31b8a8 179 Pfam PF01381 Helix-turn-helix 7 61 7.3E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS09940 a1fe732b4d1ae4fcc1ba501ada0bd6ea 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 305 2.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS09940 a1fe732b4d1ae4fcc1ba501ada0bd6ea 308 Gene3D G3DSA:1.10.3720.10 15 298 1.5E-39 T 28-03-2018 CWR44_RS09940 a1fe732b4d1ae4fcc1ba501ada0bd6ea 308 SUPERFAMILY SSF161098 26 301 2.62E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS09940 a1fe732b4d1ae4fcc1ba501ada0bd6ea 308 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 24 304 3.1E-79 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 SMART SM00437 242 508 1.6E-122 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 SMART SM00493 3 103 3.7E-32 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Gene3D G3DSA:2.70.20.10 326 454 3.9E-39 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 631 55.886 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Gene3D G3DSA:3.30.65.10 610 653 2.9E-11 T 28-03-2018 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Gene3D G3DSA:3.30.65.10 554 609 2.2E-17 T 28-03-2018 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Pfam PF01751 Toprim domain 5 113 3.9E-29 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 609 3.3E-258 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Gene3D G3DSA:1.10.460.10 135 325 9.4E-50 T 28-03-2018 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 574 610 5.4E-16 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 655 688 0.75 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 615 653 3.7E-15 T 28-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 1.1E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 368 384 1.1E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 471 485 1.1E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 1.1E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 1.1E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Gene3D G3DSA:2.20.25.10 656 689 0.0049 T 28-03-2018 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 SMART SM00436 104 192 5.3E-51 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 SUPERFAMILY SSF56712 4 587 9.16E-198 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Pfam PF01131 DNA topoisomerase 128 546 2.5E-134 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 Gene3D G3DSA:3.40.50.140 2 129 1.4E-38 T 28-03-2018 CWR44_RS08660 d44a89b778aafe51e0572f3a641abbb8 689 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 Pfam PF00579 tRNA synthetases class I (W and Y) 3 281 6.0E-80 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 326 40.541 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 325 1.4E-108 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 193 203 2.2E-24 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 161 2.2E-24 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 2.2E-24 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 2.2E-24 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 Gene3D G3DSA:1.10.240.10 200 308 7.2E-32 T 28-03-2018 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 SUPERFAMILY SSF52374 3 325 1.89E-90 T 28-03-2018 CWR44_RS07500 753aa9b4ee7f7d4d55028f8fe5117f04 329 Gene3D G3DSA:3.40.50.620 1 199 1.3E-68 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 5 646 0.0 T 28-03-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 275 329 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 55 500 5.7E-139 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 SUPERFAMILY SSF81442 42 555 4.32E-168 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 222 241 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 319 334 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 378 396 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 93 116 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 193 211 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 406 425 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 343 364 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 46 71 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 120 144 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 456 477 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 174 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 PRINTS PR01165 Cytochrome c oxidase subunit I signature 273 294 1.4E-93 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 Gene3D G3DSA:1.20.210.10 42 557 3.1E-179 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07790 be21dda95ed633a1aa433808e71f683e 662 Gene3D G3DSA:1.10.287.70 570 637 2.9E-9 T 28-03-2018 CWR44_RS01645 cddc5b41b60dbb84ddc20340cde663d5 252 Pfam PF13847 Methyltransferase domain 37 185 3.7E-18 T 28-03-2018 IPR025714 Methyltransferase domain CWR44_RS01645 cddc5b41b60dbb84ddc20340cde663d5 252 Gene3D G3DSA:3.40.50.150 25 245 3.3E-30 T 28-03-2018 CWR44_RS01645 cddc5b41b60dbb84ddc20340cde663d5 252 SUPERFAMILY SSF53335 15 242 9.82E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 SUPERFAMILY SSF63418 3 99 1.57E-20 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 484 30.974 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 SUPERFAMILY SSF53244 332 467 6.8E-32 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 SUPERFAMILY SSF53623 99 331 7.06E-70 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 Gene3D G3DSA:3.90.190.20 337 491 6.9E-36 T 28-03-2018 CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 20 475 5.0E-134 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 Pfam PF01225 Mur ligase family, catalytic domain 23 82 5.4E-9 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 Pfam PF08245 Mur ligase middle domain 108 311 6.2E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 414 2.7E-17 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 Gene3D G3DSA:3.40.1390.10 1 98 1.3E-23 T 28-03-2018 CWR44_RS07600 9c113e1372cf1b41faa0750038e2ca6c 494 Gene3D G3DSA:3.40.1190.10 99 336 1.6E-57 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS07950 b8e9f3e5af7009eec41b150381b689a8 219 Pfam PF02254 TrkA-N domain 5 120 9.2E-30 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CWR44_RS07950 b8e9f3e5af7009eec41b150381b689a8 219 Gene3D G3DSA:3.40.50.720 3 135 8.4E-24 T 28-03-2018 CWR44_RS07950 b8e9f3e5af7009eec41b150381b689a8 219 SUPERFAMILY SSF51735 4 133 7.28E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS07950 b8e9f3e5af7009eec41b150381b689a8 219 SUPERFAMILY SSF116726 133 215 1.7E-19 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR44_RS07950 b8e9f3e5af7009eec41b150381b689a8 219 Pfam PF02080 TrkA-C domain 150 216 1.4E-14 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR44_RS07950 b8e9f3e5af7009eec41b150381b689a8 219 Gene3D G3DSA:3.30.70.1450 136 218 6.8E-20 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CWR44_RS03100 4ae48e8f8e5b43ede256a9fc63ee9731 261 SUPERFAMILY SSF54001 1 259 1.94E-72 T 28-03-2018 CWR44_RS03100 4ae48e8f8e5b43ede256a9fc63ee9731 261 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 2.0E-14 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CWR44_RS03100 4ae48e8f8e5b43ede256a9fc63ee9731 261 PRINTS PR01543 Arylamine N-acetyltransferase signature 101 126 2.0E-14 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CWR44_RS03100 4ae48e8f8e5b43ede256a9fc63ee9731 261 PRINTS PR01543 Arylamine N-acetyltransferase signature 154 173 2.0E-14 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CWR44_RS03100 4ae48e8f8e5b43ede256a9fc63ee9731 261 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 2.0E-14 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CWR44_RS03100 4ae48e8f8e5b43ede256a9fc63ee9731 261 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 2.0E-14 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CWR44_RS03100 4ae48e8f8e5b43ede256a9fc63ee9731 261 Gene3D G3DSA:3.30.2140.10 155 261 1.8E-10 T 28-03-2018 CWR44_RS03100 4ae48e8f8e5b43ede256a9fc63ee9731 261 Gene3D G3DSA:3.30.2140.10 1 143 1.9E-29 T 28-03-2018 CWR44_RS03100 4ae48e8f8e5b43ede256a9fc63ee9731 261 Pfam PF00797 N-acetyltransferase 21 255 7.9E-68 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CWR44_RS01960 ccd9c822c8002e37f6d9639ac21affb6 255 SUPERFAMILY SSF110399 1 239 1.31E-76 T 28-03-2018 CWR44_RS01960 ccd9c822c8002e37f6d9639ac21affb6 255 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 39.864 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CWR44_RS01960 ccd9c822c8002e37f6d9639ac21affb6 255 Pfam PF05690 Thiazole biosynthesis protein ThiG 3 248 1.7E-101 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CWR44_RS01960 ccd9c822c8002e37f6d9639ac21affb6 255 Gene3D G3DSA:3.20.20.70 1 253 2.0E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS12390 8de2ae7fe5d1bf7b28c9d0bfc7188bc8 100 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 25.645 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CWR44_RS12390 8de2ae7fe5d1bf7b28c9d0bfc7188bc8 100 SUPERFAMILY SSF141000 3 94 5.36E-30 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CWR44_RS12390 8de2ae7fe5d1bf7b28c9d0bfc7188bc8 100 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 1.7E-28 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CWR44_RS12390 8de2ae7fe5d1bf7b28c9d0bfc7188bc8 100 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 2.8E-20 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CWR44_RS01020 c6402b820825905467abea3603487498 109 SUPERFAMILY SSF103481 6 101 1.11E-15 T 28-03-2018 CWR44_RS01020 c6402b820825905467abea3603487498 109 Pfam PF00893 Small Multidrug Resistance protein 1 90 1.3E-21 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 Gene3D G3DSA:3.40.50.300 83 364 7.0E-118 T 28-03-2018 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 Gene3D G3DSA:2.40.30.20 3 82 1.3E-36 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 8.1E-251 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 92 3.6E-17 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 SUPERFAMILY SSF47917 372 499 2.09E-47 T 28-03-2018 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 50.592 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 PIRSF PIRSF039088 1 501 1.5E-245 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 Gene3D G3DSA:1.20.150.20 373 498 6.7E-49 T 28-03-2018 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 SUPERFAMILY SSF50615 11 94 3.4E-29 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 494 1.7E-45 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 SUPERFAMILY SSF52540 95 370 1.9E-97 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00155 32a972d63c6f4e867ad3a9dfdb3d6fb3 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 7.2E-72 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR44_RS04560 8a8302fab70bde15d375495cd636070f 257 Gene3D G3DSA:3.40.190.80 148 257 3.0E-17 T 28-03-2018 CWR44_RS04560 8a8302fab70bde15d375495cd636070f 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 61 77 4.4E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS04560 8a8302fab70bde15d375495cd636070f 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 172 193 4.4E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS04560 8a8302fab70bde15d375495cd636070f 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 39 59 4.4E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS04560 8a8302fab70bde15d375495cd636070f 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 4.4E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS04560 8a8302fab70bde15d375495cd636070f 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 132 155 4.4E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS04560 8a8302fab70bde15d375495cd636070f 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 203 227 4.4E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS04560 8a8302fab70bde15d375495cd636070f 257 Pfam PF00459 Inositol monophosphatase family 27 253 6.3E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS04560 8a8302fab70bde15d375495cd636070f 257 Gene3D G3DSA:3.30.540.10 6 147 6.5E-31 T 28-03-2018 CWR44_RS04560 8a8302fab70bde15d375495cd636070f 257 SUPERFAMILY SSF56655 16 254 7.07E-55 T 28-03-2018 CWR44_RS07925 7d602577ba7e423d320a06fefba32f4d 567 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS07925 7d602577ba7e423d320a06fefba32f4d 567 Pfam PF01609 Transposase DDE domain 264 515 8.9E-38 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS07925 7d602577ba7e423d320a06fefba32f4d 567 Gene3D G3DSA:3.90.350.10 263 498 2.2E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS06280 b066989a529dcfff47091f1dbffbbdfa 338 Pfam PF01032 FecCD transport family 20 334 2.4E-86 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR44_RS06280 b066989a529dcfff47091f1dbffbbdfa 338 Gene3D G3DSA:1.10.3470.10 5 337 1.3E-65 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS06280 b066989a529dcfff47091f1dbffbbdfa 338 SUPERFAMILY SSF81345 4 334 3.27E-76 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWR44_RS07970 9fc616c7292c61b7c9ade5a1479878a5 72 Pfam PF07288 Protein of unknown function (DUF1447) 3 69 1.5E-26 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CWR44_RS07970 9fc616c7292c61b7c9ade5a1479878a5 72 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 3 64 4.0E-29 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CWR44_RS07970 9fc616c7292c61b7c9ade5a1479878a5 72 Hamap MF_01553 UPF0356 protein . 2 70 20.136 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CWR44_RS05035 586605c601a37827bc3f5a1aebf4f971 171 SUPERFAMILY SSF55729 7 139 2.02E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS05035 586605c601a37827bc3f5a1aebf4f971 171 Pfam PF13673 Acetyltransferase (GNAT) domain 48 129 1.2E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS05035 586605c601a37827bc3f5a1aebf4f971 171 Gene3D G3DSA:3.40.630.30 1 145 7.4E-20 T 28-03-2018 CWR44_RS05335 ba45f8133b40c9767ca0e9c0f989db8e 221 SUPERFAMILY SSF50715 3 188 1.92E-54 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CWR44_RS05335 ba45f8133b40c9767ca0e9c0f989db8e 221 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 13 94 5.0E-41 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CWR44_RS05335 ba45f8133b40c9767ca0e9c0f989db8e 221 Pfam PF01386 Ribosomal L25p family 8 91 6.0E-22 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CWR44_RS05335 ba45f8133b40c9767ca0e9c0f989db8e 221 Gene3D G3DSA:2.40.240.10 11 94 1.4E-25 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CWR44_RS05335 ba45f8133b40c9767ca0e9c0f989db8e 221 Gene3D G3DSA:2.170.120.20 98 186 2.7E-27 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CWR44_RS05335 ba45f8133b40c9767ca0e9c0f989db8e 221 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 12 179 6.4E-49 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CWR44_RS05335 ba45f8133b40c9767ca0e9c0f989db8e 221 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 2 182 26.159 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CWR44_RS05335 ba45f8133b40c9767ca0e9c0f989db8e 221 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 101 181 7.7E-26 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 5 381 2.7E-105 T 28-03-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 48 69 2.0E-9 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 169 187 2.0E-9 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 75 95 2.0E-9 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 310 331 2.0E-9 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 SUPERFAMILY SSF55035 109 215 5.1E-32 T 28-03-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 Gene3D G3DSA:3.90.770.10 2 133 2.6E-19 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 Gene3D G3DSA:3.90.770.10 134 372 2.2E-55 T 28-03-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 22 382 1.6E-103 T 28-03-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 368 381 - T 28-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 SUPERFAMILY SSF56542 225 424 3.79E-99 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 SUPERFAMILY SSF56542 6 117 3.79E-99 T 28-03-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02195 3bb12b62975b33fc6328d3c877b94f3e 425 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 171 185 - T 28-03-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS12645 4dcabbc59f98861441b75e2236fa01fc 46 SMART SM00794 2 46 1.3E-21 T 28-03-2018 IPR009229 Staphylococcal AgrD CWR44_RS12645 4dcabbc59f98861441b75e2236fa01fc 46 TIGRFAM TIGR04223 quorum_AgrD: cyclic lactone autoinducer peptide 7 43 2.4E-11 T 28-03-2018 IPR009229 Staphylococcal AgrD CWR44_RS12645 4dcabbc59f98861441b75e2236fa01fc 46 Pfam PF05931 Staphylococcal AgrD protein 4 45 5.6E-21 T 28-03-2018 IPR009229 Staphylococcal AgrD CWR44_RS05920 5a8967e7fd3e3da582ea97aa38fa4ea8 249 Pfam PF06778 Chlorite dismutase 33 237 9.1E-76 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CWR44_RS05920 5a8967e7fd3e3da582ea97aa38fa4ea8 249 Gene3D G3DSA:3.30.70.1100 140 245 4.3E-29 T 28-03-2018 CWR44_RS05920 5a8967e7fd3e3da582ea97aa38fa4ea8 249 Hamap MF_01442 Putative heme-dependent peroxidase . 1 249 54.827 T 28-03-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family CWR44_RS05920 5a8967e7fd3e3da582ea97aa38fa4ea8 249 SUPERFAMILY SSF54909 1 248 7.24E-91 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CWR44_RS05920 5a8967e7fd3e3da582ea97aa38fa4ea8 249 Gene3D G3DSA:3.30.70.1030 4 137 3.3E-36 T 28-03-2018 CWR44_RS05845 140b40a6cd51c78057149298f7617944 119 SUPERFAMILY SSF89442 2 119 1.02E-47 T 28-03-2018 IPR014934 Protein of unknown function DUF1806 CWR44_RS05845 140b40a6cd51c78057149298f7617944 119 Gene3D G3DSA:2.70.180.10 1 117 2.2E-48 T 28-03-2018 IPR014934 Protein of unknown function DUF1806 CWR44_RS05845 140b40a6cd51c78057149298f7617944 119 Pfam PF08830 Protein of unknown function (DUF1806) 4 117 5.1E-49 T 28-03-2018 IPR014934 Protein of unknown function DUF1806 CWR44_RS02095 fecd1ecc781dd55db6bb344c35e29ca2 357 SUPERFAMILY SSF56300 119 288 3.92E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS02095 fecd1ecc781dd55db6bb344c35e29ca2 357 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 67 287 2.1E-26 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CWR44_RS02095 fecd1ecc781dd55db6bb344c35e29ca2 357 SMART SM00854 63 288 5.1E-35 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CWR44_RS02095 fecd1ecc781dd55db6bb344c35e29ca2 357 Gene3D G3DSA:3.60.21.10 93 349 3.1E-23 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS01210 45513e8321288697bc75962104973bd5 202 Gene3D G3DSA:3.10.300.10 1 194 1.0E-55 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR44_RS01210 45513e8321288697bc75962104973bd5 202 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 3 184 3.8E-48 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR44_RS01210 45513e8321288697bc75962104973bd5 202 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 3 187 7.9E-48 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR44_RS01210 45513e8321288697bc75962104973bd5 202 SUPERFAMILY SSF50486 2 193 3.22E-56 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CWR44_RS01210 45513e8321288697bc75962104973bd5 202 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 1 187 30.606 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CWR44_RS01485 875aecbe99dda301120a7b872c32b7b0 344 Gene3D G3DSA:3.30.450.20 6 167 3.2E-7 T 28-03-2018 CWR44_RS01485 875aecbe99dda301120a7b872c32b7b0 344 Pfam PF07730 Histidine kinase 149 214 4.6E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CWR44_RS01485 875aecbe99dda301120a7b872c32b7b0 344 SMART SM00387 252 344 1.0E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01485 875aecbe99dda301120a7b872c32b7b0 344 SUPERFAMILY SSF55874 220 343 1.83E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01485 875aecbe99dda301120a7b872c32b7b0 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 302 9.6E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS01485 875aecbe99dda301120a7b872c32b7b0 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 324 9.6E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS01485 875aecbe99dda301120a7b872c32b7b0 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 343 9.6E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS01485 875aecbe99dda301120a7b872c32b7b0 344 Gene3D G3DSA:3.30.565.10 171 344 7.4E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01485 875aecbe99dda301120a7b872c32b7b0 344 PIRSF PIRSF037432 1 344 2.3E-195 T 28-03-2018 IPR017203 Signal transduction histidine kinase, NreB GO:0000155|GO:0004673|GO:0005506|GO:0005524|GO:0005737|GO:0018106 CWR44_RS01485 875aecbe99dda301120a7b872c32b7b0 344 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 257 343 2.1E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 Gene3D G3DSA:3.50.50.60 254 340 1.3E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 SUPERFAMILY SSF55424 349 473 1.41E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 Gene3D G3DSA:3.40.50.720 3 50 0.13 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 333 8.3E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 5.7E-37 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 5.7E-37 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 320 5.7E-37 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 285 5.7E-37 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 5.7E-37 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 SUPERFAMILY SSF51905 2 343 3.79E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 313 320 1.1E-63 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 349 370 1.1E-63 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.1E-63 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 416 431 1.1E-63 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 458 1.1E-63 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 1.1E-63 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.1E-63 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 1.1E-63 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 284 1.1E-63 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 Gene3D G3DSA:1.10.287.990 51 105 7.2E-21 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 474 5.6E-151 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 Gene3D G3DSA:3.50.50.60 129 253 2.4E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 353 462 2.5E-26 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 PIRSF PIRSF000350 1 468 2.1E-81 T 28-03-2018 CWR44_RS10515 db40581007d01d8b89960cc85ca3bc6b 474 Gene3D G3DSA:3.30.390.30 341 472 3.9E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS02535 1fc0751d8e742b18e320c937166fbf9d 393 Pfam PF01546 Peptidase family M20/M25/M40 74 386 3.5E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS02535 1fc0751d8e742b18e320c937166fbf9d 393 Gene3D G3DSA:3.40.630.10 1 267 1.8E-61 T 28-03-2018 CWR44_RS02535 1fc0751d8e742b18e320c937166fbf9d 393 Gene3D G3DSA:3.40.630.10 268 393 1.1E-17 T 28-03-2018 CWR44_RS02535 1fc0751d8e742b18e320c937166fbf9d 393 PIRSF PIRSF005962 1 393 4.6E-119 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS02535 1fc0751d8e742b18e320c937166fbf9d 393 Pfam PF07687 Peptidase dimerisation domain 184 279 1.3E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS02535 1fc0751d8e742b18e320c937166fbf9d 393 SUPERFAMILY SSF53187 3 199 1.32E-82 T 28-03-2018 CWR44_RS02535 1fc0751d8e742b18e320c937166fbf9d 393 SUPERFAMILY SSF53187 300 392 1.32E-82 T 28-03-2018 CWR44_RS02535 1fc0751d8e742b18e320c937166fbf9d 393 SUPERFAMILY SSF55031 186 298 3.4E-27 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS02535 1fc0751d8e742b18e320c937166fbf9d 393 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 378 1.5E-108 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS09780 379b69464756a93c622b2c92bbca58b4 156 Gene3D G3DSA:3.10.129.10 3 142 1.1E-34 T 28-03-2018 CWR44_RS09780 379b69464756a93c622b2c92bbca58b4 156 Pfam PF03061 Thioesterase superfamily 18 102 1.5E-18 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CWR44_RS09780 379b69464756a93c622b2c92bbca58b4 156 SUPERFAMILY SSF54637 4 131 5.57E-38 T 28-03-2018 IPR029069 HotDog domain CWR44_RS09780 379b69464756a93c622b2c92bbca58b4 156 PIRSF PIRSF003230 2 135 4.2E-30 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CWR44_RS09780 379b69464756a93c622b2c92bbca58b4 156 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 11 122 2.2E-30 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CWR44_RS10790 37cf784a23476f0eb525491d9cfb8752 328 Gene3D G3DSA:1.10.287.40 188 289 0.001 T 28-03-2018 CWR44_RS10790 37cf784a23476f0eb525491d9cfb8752 328 Hamap MF_01562 UPF0365 protein . 1 321 47.994 T 28-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity CWR44_RS10790 37cf784a23476f0eb525491d9cfb8752 328 Pfam PF12127 SigmaW regulon antibacterial 7 318 1.7E-162 T 28-03-2018 IPR022853 Uncharacterised protein family YdfA-immunity CWR44_RS11820 50d9d079d6891eaf87fca6914bd26d28 157 Gene3D G3DSA:3.90.79.10 1 133 1.2E-14 T 28-03-2018 CWR44_RS11820 50d9d079d6891eaf87fca6914bd26d28 157 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 2 154 6.7E-56 T 28-03-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 CWR44_RS11820 50d9d079d6891eaf87fca6914bd26d28 157 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CWR44_RS11820 50d9d079d6891eaf87fca6914bd26d28 157 SUPERFAMILY SSF55811 6 107 4.74E-17 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR44_RS11820 50d9d079d6891eaf87fca6914bd26d28 157 Pfam PF00293 NUDIX domain 27 102 3.0E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR44_RS06935 d8ad5d278c27e153e174f46936e026ef 253 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 242 1.4E-57 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06935 d8ad5d278c27e153e174f46936e026ef 253 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 252 41.306 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06935 d8ad5d278c27e153e174f46936e026ef 253 Pfam PF00121 Triosephosphate isomerase 5 248 6.1E-95 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06935 d8ad5d278c27e153e174f46936e026ef 253 Gene3D G3DSA:3.20.20.70 1 253 2.6E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS06935 d8ad5d278c27e153e174f46936e026ef 253 ProSitePatterns PS00171 Triosephosphate isomerase active site. 167 177 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06935 d8ad5d278c27e153e174f46936e026ef 253 SUPERFAMILY SSF51351 1 250 7.2E-93 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS05985 f9b19770ea0d1cd40bd29ace98b05d25 158 SUPERFAMILY SSF55729 1 146 4.05E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS05985 f9b19770ea0d1cd40bd29ace98b05d25 158 Gene3D G3DSA:3.40.630.30 1 158 6.5E-32 T 28-03-2018 CWR44_RS05985 f9b19770ea0d1cd40bd29ace98b05d25 158 Pfam PF00583 Acetyltransferase (GNAT) family 43 130 7.0E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS08135 76cd8e80fdda84bc901fdb4099c4db85 183 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 115 121 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWR44_RS08135 76cd8e80fdda84bc901fdb4099c4db85 183 PIRSF PIRSF004553 1 179 1.2E-47 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CWR44_RS08135 76cd8e80fdda84bc901fdb4099c4db85 183 SUPERFAMILY SSF53335 1 171 1.92E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS08135 76cd8e80fdda84bc901fdb4099c4db85 183 Pfam PF03602 Conserved hypothetical protein 95 1 173 2.0E-54 T 28-03-2018 CWR44_RS08135 76cd8e80fdda84bc901fdb4099c4db85 183 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 176 2.7E-51 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CWR44_RS08135 76cd8e80fdda84bc901fdb4099c4db85 183 Gene3D G3DSA:3.40.50.150 1 183 4.6E-31 T 28-03-2018 CWR44_RS06675 87c299b010fa6a26cef4446ebf6e78e8 166 Gene3D G3DSA:3.30.1130.10 22 166 3.1E-42 T 28-03-2018 CWR44_RS06675 87c299b010fa6a26cef4446ebf6e78e8 166 Pfam PF14489 QueF-like protein 63 141 8.6E-35 T 28-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CWR44_RS06675 87c299b010fa6a26cef4446ebf6e78e8 166 SUPERFAMILY SSF55620 29 136 6.3E-28 T 28-03-2018 CWR44_RS06675 87c299b010fa6a26cef4446ebf6e78e8 166 PIRSF PIRSF027377 8 148 2.0E-63 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CWR44_RS06675 87c299b010fa6a26cef4446ebf6e78e8 166 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 28 139 2.1E-53 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CWR44_RS06675 87c299b010fa6a26cef4446ebf6e78e8 166 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 166 70.634 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 451 1.1E-137 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 330 351 2.1E-61 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 437 2.1E-61 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 2.1E-61 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 301 2.1E-61 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 2.1E-61 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.1E-61 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 2.1E-61 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.1E-61 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 395 410 2.1E-61 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 Gene3D G3DSA:3.50.50.60 1 149 4.8E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 SUPERFAMILY SSF55424 331 451 2.41E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 Gene3D G3DSA:3.50.50.60 275 356 6.1E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 Gene3D G3DSA:3.30.390.30 357 448 5.1E-27 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PIRSF PIRSF000350 1 452 3.1E-82 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 6.5E-33 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 301 6.5E-33 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 6.5E-33 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 6.5E-33 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 6.5E-33 T 28-03-2018 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 SUPERFAMILY SSF51905 1 324 5.94E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 314 7.6E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 Gene3D G3DSA:3.50.50.60 150 274 8.2E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03460 ae6bbf1b05725442e15a628fa6b413e5 453 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 442 7.8E-29 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR44_RS04695 ab38d3384cc036181b125f363121e23e 211 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 202 3.2E-27 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS04695 ab38d3384cc036181b125f363121e23e 211 SMART SM00934 2 203 3.4E-30 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS04695 ab38d3384cc036181b125f363121e23e 211 Gene3D G3DSA:3.20.20.70 1 208 2.0E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS04695 ab38d3384cc036181b125f363121e23e 211 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 2 207 3.8E-82 T 28-03-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 CWR44_RS04695 ab38d3384cc036181b125f363121e23e 211 SUPERFAMILY SSF51366 2 207 1.1E-37 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR44_RS00740 ac58612b2ce49c24a9b1777ca4d2c0c7 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 2.8E-31 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00740 ac58612b2ce49c24a9b1777ca4d2c0c7 105 Gene3D G3DSA:2.30.30.30 1 91 4.1E-38 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWR44_RS00740 ac58612b2ce49c24a9b1777ca4d2c0c7 105 SMART SM00739 2 29 2.2E-6 T 28-03-2018 IPR005824 KOW CWR44_RS00740 ac58612b2ce49c24a9b1777ca4d2c0c7 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 22.736 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00740 ac58612b2ce49c24a9b1777ca4d2c0c7 105 SUPERFAMILY SSF50104 1 99 1.5E-38 T 28-03-2018 IPR008991 Translation protein SH3-like domain CWR44_RS00740 ac58612b2ce49c24a9b1777ca4d2c0c7 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00740 ac58612b2ce49c24a9b1777ca4d2c0c7 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 101 5.9E-40 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00740 ac58612b2ce49c24a9b1777ca4d2c0c7 105 Pfam PF00467 KOW motif 5 36 9.7E-9 T 28-03-2018 IPR005824 KOW CWR44_RS11400 7b587aa92afc11a969bade6fb25efed0 351 Pfam PF00557 Metallopeptidase family M24 137 340 8.3E-63 T 28-03-2018 IPR000994 Peptidase M24 CWR44_RS11400 7b587aa92afc11a969bade6fb25efed0 351 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 130 1.9E-20 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CWR44_RS11400 7b587aa92afc11a969bade6fb25efed0 351 SUPERFAMILY SSF55920 130 350 7.59E-76 T 28-03-2018 IPR000994 Peptidase M24 CWR44_RS11400 7b587aa92afc11a969bade6fb25efed0 351 SUPERFAMILY SSF53092 8 130 1.53E-22 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CWR44_RS11400 7b587aa92afc11a969bade6fb25efed0 351 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CWR44_RS11400 7b587aa92afc11a969bade6fb25efed0 351 Gene3D G3DSA:3.40.350.10 1 113 2.2E-16 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CWR44_RS11400 7b587aa92afc11a969bade6fb25efed0 351 Gene3D G3DSA:3.90.230.10 114 351 2.2E-75 T 28-03-2018 CWR44_RS06735 835d48bfc6ff7dbfb123c57d1de80b05 171 SUPERFAMILY SSF81301 13 170 1.73E-31 T 28-03-2018 CWR44_RS06735 835d48bfc6ff7dbfb123c57d1de80b05 171 Pfam PF04229 GrpB protein 13 170 5.8E-20 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CWR44_RS06735 835d48bfc6ff7dbfb123c57d1de80b05 171 Gene3D G3DSA:3.30.460.10 6 171 3.1E-19 T 28-03-2018 CWR44_RS08260 2d517558ba6fa0cc537609e5479b9db6 44 Pfam PF05480 Staphylococcus haemolytic protein 1 43 7.7E-19 T 28-03-2018 IPR008846 Staphylococcal hemolytic protein family GO:0009405 CWR44_RS08270 2d517558ba6fa0cc537609e5479b9db6 44 Pfam PF05480 Staphylococcus haemolytic protein 1 43 7.7E-19 T 28-03-2018 IPR008846 Staphylococcal hemolytic protein family GO:0009405 CWR44_RS07795 5c705c3e1e8aa85c95ecca3e8233a455 374 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 8 230 1.4E-120 T 28-03-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 CWR44_RS07795 5c705c3e1e8aa85c95ecca3e8233a455 374 Gene3D G3DSA:1.10.287.90 20 108 5.6E-22 T 28-03-2018 CWR44_RS07795 5c705c3e1e8aa85c95ecca3e8233a455 374 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 27 102 1.3E-10 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07795 5c705c3e1e8aa85c95ecca3e8233a455 374 SUPERFAMILY SSF81464 14 110 6.21E-21 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07795 5c705c3e1e8aa85c95ecca3e8233a455 374 PIRSF PIRSF000292 1 302 3.2E-104 T 28-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CWR44_RS07795 5c705c3e1e8aa85c95ecca3e8233a455 374 SUPERFAMILY SSF49503 112 246 1.03E-39 T 28-03-2018 IPR008972 Cupredoxin CWR44_RS07795 5c705c3e1e8aa85c95ecca3e8233a455 374 Gene3D G3DSA:2.60.40.420 109 370 3.3E-36 T 28-03-2018 IPR008972 Cupredoxin CWR44_RS10945 f7e6ea7f61f46ac0b0c4f12678794fc0 242 SMART SM00796 1 203 1.7E-95 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CWR44_RS10945 f7e6ea7f61f46ac0b0c4f12678794fc0 242 SUPERFAMILY SSF160467 4 93 4.84E-13 T 28-03-2018 CWR44_RS10945 f7e6ea7f61f46ac0b0c4f12678794fc0 242 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 3 201 2.4E-69 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CWR44_RS10945 f7e6ea7f61f46ac0b0c4f12678794fc0 242 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 211 2.4E-61 T 28-03-2018 IPR010016 KipI family CWR44_RS10945 f7e6ea7f61f46ac0b0c4f12678794fc0 242 Gene3D G3DSA:2.40.100.10 87 221 8.7E-50 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS10945 f7e6ea7f61f46ac0b0c4f12678794fc0 242 SUPERFAMILY SSF50891 90 219 6.45E-47 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS10945 f7e6ea7f61f46ac0b0c4f12678794fc0 242 Gene3D G3DSA:3.30.1360.40 1 82 4.4E-12 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 Gene3D G3DSA:2.70.150.10 3 245 2.7E-33 T 28-03-2018 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 SUPERFAMILY SSF81653 152 244 1.11E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 347 353 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 Gene3D G3DSA:3.40.50.1000 464 605 2.0E-34 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 SUPERFAMILY SSF81665 94 147 2.88E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 SUPERFAMILY SSF81665 245 339 2.88E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 SUPERFAMILY SSF81665 583 616 2.88E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 SUPERFAMILY SSF56784 344 363 3.34E-55 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 SUPERFAMILY SSF56784 435 637 3.34E-55 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 Pfam PF00702 haloacid dehalogenase-like hydrolase 341 552 5.3E-38 T 28-03-2018 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 Pfam PF00122 E1-E2 ATPase 143 325 1.0E-44 T 28-03-2018 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 94 640 6.5E-169 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 557 1.4E-28 T 28-03-2018 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 463 474 1.4E-28 T 28-03-2018 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 485 495 1.4E-28 T 28-03-2018 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 194 208 1.4E-28 T 28-03-2018 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 561 573 1.4E-28 T 28-03-2018 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 345 359 1.4E-28 T 28-03-2018 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 Gene3D G3DSA:3.40.1110.10 356 463 1.6E-19 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 117 616 7.8E-87 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 538 554 2.6E-8 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 569 594 2.6E-8 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR44_RS04150 afa1bbc1e3952150e2042f504cff3197 644 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 510 526 2.6E-8 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR44_RS00870 823bb54f3789f7a2534073b58b68905d 401 Pfam PF07690 Major Facilitator Superfamily 21 301 4.0E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS00870 823bb54f3789f7a2534073b58b68905d 401 Gene3D G3DSA:1.20.1250.20 2 194 4.4E-28 T 28-03-2018 CWR44_RS00870 823bb54f3789f7a2534073b58b68905d 401 Gene3D G3DSA:1.20.1250.20 212 400 3.6E-21 T 28-03-2018 CWR44_RS00870 823bb54f3789f7a2534073b58b68905d 401 SUPERFAMILY SSF103473 14 397 1.28E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS07585 96912c437135cc453134548a8dae8f35 169 Hamap MF_01444 Putative phosphoesterase . 1 169 35.635 T 28-03-2018 IPR022932 Putative phosphoesterase YjcG CWR44_RS07585 96912c437135cc453134548a8dae8f35 169 Pfam PF13563 2'-5' RNA ligase superfamily 10 156 4.4E-20 T 28-03-2018 CWR44_RS07585 96912c437135cc453134548a8dae8f35 169 SUPERFAMILY SSF55144 1 168 1.45E-33 T 28-03-2018 IPR009097 Cyclic phosphodiesterase CWR44_RS07585 96912c437135cc453134548a8dae8f35 169 Gene3D G3DSA:3.90.1140.10 1 169 5.5E-24 T 28-03-2018 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 SUPERFAMILY SSF47384 345 426 7.65E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 Gene3D G3DSA:1.10.287.130 365 422 5.7E-17 T 28-03-2018 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 SUPERFAMILY SSF158472 198 248 6.15E-10 T 28-03-2018 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 SUPERFAMILY SSF55874 415 582 9.3E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 SMART SM00388 359 426 2.8E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 562 8.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 581 8.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 523 8.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 537 8.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 Pfam PF00512 His Kinase A (phospho-acceptor) domain 359 425 8.4E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 SMART SM00304 197 249 1.1E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 Pfam PF00672 HAMP domain 198 246 9.6E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 Gene3D G3DSA:3.30.450.20 69 364 8.4E-7 T 28-03-2018 CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 Gene3D G3DSA:3.30.565.10 440 585 2.2E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 473 583 2.1E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS10385 ccbffc02ce36af45040113a1df2b6ae8 585 SMART SM00387 472 584 7.8E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS09620 45869d86150b7479a5dd3103e78c031b 242 SUPERFAMILY SSF102114 26 199 7.06E-13 T 28-03-2018 CWR44_RS09620 45869d86150b7479a5dd3103e78c031b 242 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 3 242 1.3E-92 T 28-03-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CWR44_RS09620 45869d86150b7479a5dd3103e78c031b 242 Pfam PF13394 4Fe-4S single cluster domain 26 116 2.0E-9 T 28-03-2018 CWR44_RS09620 45869d86150b7479a5dd3103e78c031b 242 Gene3D G3DSA:3.20.20.70 25 227 2.7E-16 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS09620 45869d86150b7479a5dd3103e78c031b 242 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 239 31.954 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CWR44_RS09620 45869d86150b7479a5dd3103e78c031b 242 PIRSF PIRSF000370 2 242 4.7E-43 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CWR44_RS09620 45869d86150b7479a5dd3103e78c031b 242 Pfam PF04055 Radical SAM superfamily 28 126 4.5E-9 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS04290 7a7c52cd13fd6f6e7ee9ffdf0f635fe1 247 Gene3D G3DSA:3.20.20.190 1 247 2.4E-62 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR44_RS04290 7a7c52cd13fd6f6e7ee9ffdf0f635fe1 247 SUPERFAMILY SSF51695 3 244 4.19E-62 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR44_RS04290 7a7c52cd13fd6f6e7ee9ffdf0f635fe1 247 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 240 2.8E-44 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CWR44_RS03665 a086c3425ed9af0637383d55588fc5ca 283 Pfam PF02569 Pantoate-beta-alanine ligase 3 279 2.2E-101 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CWR44_RS03665 a086c3425ed9af0637383d55588fc5ca 283 Gene3D G3DSA:3.40.50.620 1 175 1.3E-78 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS03665 a086c3425ed9af0637383d55588fc5ca 283 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 27 76 3.1E-7 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR44_RS03665 a086c3425ed9af0637383d55588fc5ca 283 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 3 280 2.6E-107 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CWR44_RS03665 a086c3425ed9af0637383d55588fc5ca 283 SUPERFAMILY SSF52374 3 280 8.85E-105 T 28-03-2018 CWR44_RS03665 a086c3425ed9af0637383d55588fc5ca 283 Hamap MF_00158 Pantothenate synthetase [panC]. 3 280 38.864 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CWR44_RS03665 a086c3425ed9af0637383d55588fc5ca 283 Gene3D G3DSA:3.30.1300.10 176 283 1.2E-26 T 28-03-2018 CWR44_RS04710 4095d81ba4fd68c0364c5fc5715e29d7 33 Pfam PF10855 Protein of unknown function (DUF2648) 1 33 8.2E-9 T 28-03-2018 IPR022561 Protein of unknown function DUF2648 CWR44_RS04710 4095d81ba4fd68c0364c5fc5715e29d7 33 ProDom PD610536 SE2200 SAV2627.1 SA2420.1 MW2548 1 33 0.005 T 28-03-2018 IPR022561 Protein of unknown function DUF2648 CWR44_RS03615 db1d92c702a059bd3e0ed2f6ab8eba5e 334 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 9 304 1.4E-40 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CWR44_RS03615 db1d92c702a059bd3e0ed2f6ab8eba5e 334 Gene3D G3DSA:3.30.420.40 134 282 8.6E-42 T 28-03-2018 CWR44_RS03615 db1d92c702a059bd3e0ed2f6ab8eba5e 334 SUPERFAMILY SSF53067 5 117 5.31E-21 T 28-03-2018 CWR44_RS03615 db1d92c702a059bd3e0ed2f6ab8eba5e 334 SUPERFAMILY SSF53067 120 307 9.58E-47 T 28-03-2018 CWR44_RS03615 db1d92c702a059bd3e0ed2f6ab8eba5e 334 Gene3D G3DSA:3.30.420.40 2 133 1.3E-15 T 28-03-2018 CWR44_RS08300 72ccb2a0711d8f94b983ddfb701ed070 311 SUPERFAMILY SSF81799 113 214 6.67E-36 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS08300 72ccb2a0711d8f94b983ddfb701ed070 311 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 308 1.3E-121 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS08300 72ccb2a0711d8f94b983ddfb701ed070 311 Pfam PF01795 MraW methylase family 2 308 2.8E-134 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS08300 72ccb2a0711d8f94b983ddfb701ed070 311 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 37.534 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS08300 72ccb2a0711d8f94b983ddfb701ed070 311 Gene3D G3DSA:1.10.150.170 111 216 5.8E-40 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS08300 72ccb2a0711d8f94b983ddfb701ed070 311 PIRSF PIRSF004486 1 311 6.5E-106 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS08300 72ccb2a0711d8f94b983ddfb701ed070 311 SUPERFAMILY SSF53335 214 308 3.62E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS08300 72ccb2a0711d8f94b983ddfb701ed070 311 SUPERFAMILY SSF53335 3 112 3.62E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 Gene3D G3DSA:3.40.50.740 632 984 5.9E-39 T 28-03-2018 CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 Gene3D G3DSA:3.40.228.10 223 631 1.6E-93 T 28-03-2018 CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 Pfam PF01568 Molydopterin dinucleotide binding domain 1078 1188 2.4E-20 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 SUPERFAMILY SSF50692 1074 1225 7.69E-45 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 SMART SM00926 40 102 8.1E-5 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 Gene3D G3DSA:2.40.40.20 1039 1227 3.3E-43 T 28-03-2018 CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 SUPERFAMILY SSF53706 7 1055 0.0 T 28-03-2018 CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 Pfam PF00384 Molybdopterin oxidoreductase 105 818 1.4E-160 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 Gene3D G3DSA:2.20.25.90 52 95 2.2E-26 T 28-03-2018 CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 6 37 2.8E-9 T 28-03-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 6 1226 0.0 T 28-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CWR44_RS01510 a5497e4a32a1b09efa134d37b6214181 1227 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 45 63 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CWR44_RS01655 57d027260cee03823ba4e989576eb0b5 207 PIRSF PIRSF032442 1 203 1.7E-56 T 28-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 CWR44_RS01655 57d027260cee03823ba4e989576eb0b5 207 Gene3D G3DSA:3.90.70.10 19 206 9.6E-12 T 28-03-2018 CWR44_RS01655 57d027260cee03823ba4e989576eb0b5 207 Pfam PF13529 Peptidase_C39 like family 8 158 2.5E-18 T 28-03-2018 CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 181 2.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 193 212 2.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 132 2.2E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 180 208 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 212 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 183 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 231 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 46 63 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 248 268 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 132 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 54 284 3.3E-59 T 28-03-2018 CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 Gene3D G3DSA:3.40.50.720 2 288 1.8E-74 T 28-03-2018 CWR44_RS02250 0315ea0c4acbff42a859df1dd24817e2 289 SUPERFAMILY SSF51735 43 286 8.73E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS05765 85c38c8fbb6b05ead3b820581a0c9970 288 Gene3D G3DSA:3.40.50.1000 194 255 0.056 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS05765 85c38c8fbb6b05ead3b820581a0c9970 288 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 253 4.3E-24 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR44_RS05765 85c38c8fbb6b05ead3b820581a0c9970 288 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 28-03-2018 CWR44_RS05765 85c38c8fbb6b05ead3b820581a0c9970 288 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 280 6.0E-71 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS05765 85c38c8fbb6b05ead3b820581a0c9970 288 SUPERFAMILY SSF56784 1 284 1.3E-67 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS05765 85c38c8fbb6b05ead3b820581a0c9970 288 Gene3D G3DSA:3.30.1240.10 89 193 4.6E-26 T 28-03-2018 CWR44_RS05765 85c38c8fbb6b05ead3b820581a0c9970 288 Gene3D G3DSA:3.30.1240.10 24 88 1.6E-7 T 28-03-2018 CWR44_RS05765 85c38c8fbb6b05ead3b820581a0c9970 288 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 280 2.6E-59 T 28-03-2018 IPR000150 Cof family GO:0016787 CWR44_RS05765 85c38c8fbb6b05ead3b820581a0c9970 288 Gene3D G3DSA:3.40.50.1000 1 23 0.11 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS05765 85c38c8fbb6b05ead3b820581a0c9970 288 ProSitePatterns PS01229 Hypothetical cof family signature 2. 234 256 - T 28-03-2018 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 115 3.0E-13 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 Pfam PF00361 Proton-conducting membrane transporter 128 428 5.0E-63 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 258 280 1.1E-8 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 366 388 1.1E-8 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 79 99 1.1E-8 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 529 550 1.1E-8 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 218 239 3.7E-41 T 28-03-2018 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 435 454 3.7E-41 T 28-03-2018 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 3.7E-41 T 28-03-2018 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 308 320 3.7E-41 T 28-03-2018 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 105 125 3.7E-41 T 28-03-2018 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 240 266 3.7E-41 T 28-03-2018 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 Pfam PF13244 Domain of unknown function (DUF4040) 630 694 2.3E-22 T 28-03-2018 IPR025383 Domain of unknown function DUF4040 CWR44_RS07325 c26336e9d497450afaf54019599f89da 803 TIGRFAM TIGR00940 2a6301s01: monovalent cation:proton antiporter 4 792 0.0 T 28-03-2018 IPR005663 Monovalent cation proton antiporter subunit A GO:0015077|GO:0030004 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 Gene3D G3DSA:1.10.1200.70 333 420 8.0E-20 T 28-03-2018 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 SUPERFAMILY SSF69075 325 420 4.58E-12 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 SUPERFAMILY SSF69742 1 158 5.49E-44 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 8.7E-42 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 420 3.7E-133 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 PIRSF PIRSF000445 1 435 2.9E-139 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 305 1.2E-42 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 325 418 2.9E-19 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 Gene3D G3DSA:3.40.50.720 158 320 1.4E-19 T 28-03-2018 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 27.314 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CWR44_RS11225 b11cae1a2a6f3eec8dab11bea1ba4ad7 448 SUPERFAMILY SSF51735 162 315 5.09E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 SUPERFAMILY SSF55874 239 380 2.49E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 SUPERFAMILY SSF47384 159 231 1.28E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 Gene3D G3DSA:3.30.565.10 242 380 3.8E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 280 380 8.7E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 Gene3D G3DSA:1.10.287.130 162 232 1.3E-10 T 28-03-2018 CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 SMART SM00387 276 380 2.8E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 SMART SM00388 171 239 1.0E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 172 232 5.3E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 380 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 362 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 327 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS04675 4f6fc09b7ea44f9f4350d0dfe41f6427 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 341 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS09845 54ebb5bc581ef8fcf5f895660e11285b 363 SUPERFAMILY SSF51735 4 170 2.39E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS09845 54ebb5bc581ef8fcf5f895660e11285b 363 Gene3D G3DSA:3.30.70.260 292 360 4.2E-6 T 28-03-2018 CWR44_RS09845 54ebb5bc581ef8fcf5f895660e11285b 363 SUPERFAMILY SSF48179 175 283 7.37E-33 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR44_RS09845 54ebb5bc581ef8fcf5f895660e11285b 363 Gene3D G3DSA:1.10.3660.10 183 291 1.7E-22 T 28-03-2018 CWR44_RS09845 54ebb5bc581ef8fcf5f895660e11285b 363 Gene3D G3DSA:3.40.50.720 1 172 1.2E-18 T 28-03-2018 CWR44_RS09845 54ebb5bc581ef8fcf5f895660e11285b 363 Pfam PF02153 Prephenate dehydrogenase 16 273 7.9E-66 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CWR44_RS09845 54ebb5bc581ef8fcf5f895660e11285b 363 SUPERFAMILY SSF55021 295 361 1.22E-6 T 28-03-2018 CWR44_RS10205 af6586874959dcd7dd9c4775ab79fdf0 187 SUPERFAMILY SSF102405 1 176 4.12E-62 T 28-03-2018 CWR44_RS10205 af6586874959dcd7dd9c4775ab79fdf0 187 Gene3D G3DSA:3.40.50.450 1 180 3.5E-31 T 28-03-2018 CWR44_RS10205 af6586874959dcd7dd9c4775ab79fdf0 187 Pfam PF06908 Protein of unknown function (DUF1273) 4 171 1.3E-67 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CWR44_RS10205 af6586874959dcd7dd9c4775ab79fdf0 187 PIRSF PIRSF021290 1 179 1.5E-69 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CWR44_RS10205 af6586874959dcd7dd9c4775ab79fdf0 187 Hamap MF_01575 UPF0398 protein . 1 177 34.676 T 28-03-2018 IPR010697 Protein of unknown function DUF1273 CWR44_RS01160 8ec8debb3dcb81379c42cb8e63c20df0 377 SUPERFAMILY SSF55031 174 281 2.62E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS01160 8ec8debb3dcb81379c42cb8e63c20df0 377 Pfam PF07687 Peptidase dimerisation domain 175 267 2.3E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS01160 8ec8debb3dcb81379c42cb8e63c20df0 377 SUPERFAMILY SSF53187 288 373 9.02E-76 T 28-03-2018 CWR44_RS01160 8ec8debb3dcb81379c42cb8e63c20df0 377 SUPERFAMILY SSF53187 4 187 9.02E-76 T 28-03-2018 CWR44_RS01160 8ec8debb3dcb81379c42cb8e63c20df0 377 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 7 357 4.9E-118 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS01160 8ec8debb3dcb81379c42cb8e63c20df0 377 Gene3D G3DSA:3.40.630.10 2 240 1.2E-45 T 28-03-2018 CWR44_RS01160 8ec8debb3dcb81379c42cb8e63c20df0 377 Gene3D G3DSA:3.40.630.10 241 377 1.1E-14 T 28-03-2018 CWR44_RS01160 8ec8debb3dcb81379c42cb8e63c20df0 377 PIRSF PIRSF005962 1 374 3.0E-118 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS01160 8ec8debb3dcb81379c42cb8e63c20df0 377 Pfam PF01546 Peptidase family M20/M25/M40 64 355 3.7E-29 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS08720 27927ca9d3dc917404829f07ff243916 428 SUPERFAMILY SSF50156 176 267 9.99E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS08720 27927ca9d3dc917404829f07ff243916 428 Pfam PF02163 Peptidase family M50 10 413 1.0E-75 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CWR44_RS08720 27927ca9d3dc917404829f07ff243916 428 Gene3D G3DSA:2.30.42.10 199 292 6.6E-14 T 28-03-2018 CWR44_RS08720 27927ca9d3dc917404829f07ff243916 428 Pfam PF13180 PDZ domain 203 266 6.9E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS08720 27927ca9d3dc917404829f07ff243916 428 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 427 1.2E-82 T 28-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CWR44_RS03550 53c78b6a8572a54776e7fbcc4df234cf 536 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 277 474 6.9E-26 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CWR44_RS03550 53c78b6a8572a54776e7fbcc4df234cf 536 Gene3D G3DSA:3.30.420.40 269 522 4.2E-30 T 28-03-2018 CWR44_RS03550 53c78b6a8572a54776e7fbcc4df234cf 536 SUPERFAMILY SSF53067 273 519 7.12E-13 T 28-03-2018 CWR44_RS03550 53c78b6a8572a54776e7fbcc4df234cf 536 SUPERFAMILY SSF53067 16 265 2.33E-32 T 28-03-2018 CWR44_RS03550 53c78b6a8572a54776e7fbcc4df234cf 536 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 16 241 1.7E-18 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CWR44_RS03550 53c78b6a8572a54776e7fbcc4df234cf 536 Gene3D G3DSA:3.30.420.40 10 268 2.5E-38 T 28-03-2018 CWR44_RS01700 a02ce63bb354bdc047bc386931e89fe1 310 Gene3D G3DSA:3.40.50.720 1 178 6.9E-27 T 28-03-2018 CWR44_RS01700 a02ce63bb354bdc047bc386931e89fe1 310 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 152 6.6E-39 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWR44_RS01700 a02ce63bb354bdc047bc386931e89fe1 310 SUPERFAMILY SSF48179 180 305 1.33E-32 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR44_RS01700 a02ce63bb354bdc047bc386931e89fe1 310 SUPERFAMILY SSF51735 1 163 4.65E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS01700 a02ce63bb354bdc047bc386931e89fe1 310 Gene3D G3DSA:1.10.1040.10 179 310 6.6E-34 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR44_RS01700 a02ce63bb354bdc047bc386931e89fe1 310 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 307 2.5E-84 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWR44_RS01700 a02ce63bb354bdc047bc386931e89fe1 310 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 304 5.5E-35 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWR44_RS06080 0a539254a4b638bdf7dd1c5291234e3c 317 SUPERFAMILY SSF81345 7 312 3.14E-59 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWR44_RS06080 0a539254a4b638bdf7dd1c5291234e3c 317 Pfam PF01032 FecCD transport family 15 312 1.3E-65 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR44_RS06080 0a539254a4b638bdf7dd1c5291234e3c 317 Gene3D G3DSA:1.10.3470.10 6 317 1.2E-51 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS00365 b8efc4060ef897b87ef8ddd9205388ed 316 SUPERFAMILY SSF161111 18 217 1.28E-59 T 28-03-2018 CWR44_RS00365 b8efc4060ef897b87ef8ddd9205388ed 316 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 297 1.9E-94 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR44_RS00365 b8efc4060ef897b87ef8ddd9205388ed 316 Gene3D G3DSA:1.20.1510.10 18 214 7.5E-61 T 28-03-2018 CWR44_RS00365 b8efc4060ef897b87ef8ddd9205388ed 316 SUPERFAMILY SSF160240 220 295 2.49E-12 T 28-03-2018 CWR44_RS00365 b8efc4060ef897b87ef8ddd9205388ed 316 Gene3D G3DSA:3.30.70.1350 215 299 8.7E-16 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR44_RS00365 b8efc4060ef897b87ef8ddd9205388ed 316 Pfam PF01545 Cation efflux family 24 216 1.0E-50 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR44_RS04575 161f6213be443527f5e35096599daff2 612 Pfam PF02574 Homocysteine S-methyltransferase 13 280 2.7E-55 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CWR44_RS04575 161f6213be443527f5e35096599daff2 612 SUPERFAMILY SSF82282 2 362 3.01E-98 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CWR44_RS04575 161f6213be443527f5e35096599daff2 612 Gene3D G3DSA:3.20.20.330 1 316 8.5E-82 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CWR44_RS04575 161f6213be443527f5e35096599daff2 612 SUPERFAMILY SSF51730 317 600 5.1E-65 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CWR44_RS04575 161f6213be443527f5e35096599daff2 612 Pfam PF02219 Methylenetetrahydrofolate reductase 321 575 2.5E-27 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWR44_RS04575 161f6213be443527f5e35096599daff2 612 Gene3D G3DSA:3.20.20.220 317 611 7.0E-62 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CWR44_RS01220 e7c50f4b984f9bfaa4dbc4130e1b7e36 349 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 6 333 37.02 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CWR44_RS01220 e7c50f4b984f9bfaa4dbc4130e1b7e36 349 Gene3D G3DSA:3.20.20.70 6 345 2.9E-72 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS01220 e7c50f4b984f9bfaa4dbc4130e1b7e36 349 SUPERFAMILY SSF51395 26 347 1.2E-83 T 28-03-2018 CWR44_RS01220 e7c50f4b984f9bfaa4dbc4130e1b7e36 349 PIRSF PIRSF003314 3 343 4.2E-124 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CWR44_RS01220 e7c50f4b984f9bfaa4dbc4130e1b7e36 349 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 8 331 6.3E-124 T 28-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CWR44_RS01220 e7c50f4b984f9bfaa4dbc4130e1b7e36 349 Pfam PF01070 FMN-dependent dehydrogenase 166 327 1.2E-21 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CWR44_RS06295 5e6818f910d7d3a25b246aa9710a14fd 126 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 3 118 1.2E-36 T 28-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain CWR44_RS06295 5e6818f910d7d3a25b246aa9710a14fd 126 Pfam PF03610 PTS system fructose IIA component 4 110 2.8E-22 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR44_RS06295 5e6818f910d7d3a25b246aa9710a14fd 126 Gene3D G3DSA:3.40.50.510 1 125 1.1E-25 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR44_RS06295 5e6818f910d7d3a25b246aa9710a14fd 126 SUPERFAMILY SSF53062 1 119 2.75E-29 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 Pfam PF00106 short chain dehydrogenase 5 193 4.5E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 PIRSF PIRSF000095 1 285 4.7E-111 T 28-03-2018 IPR011348 17beta-dehydrogenase GO:0004303|GO:0005737|GO:0006703|GO:0055114 Reactome: R-HSA-2453902 CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 SUPERFAMILY SSF51735 4 247 9.51E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 Gene3D G3DSA:3.40.50.720 3 284 1.9E-57 T 28-03-2018 CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 7.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 7.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS12325 4fa14d9edaa74b0aa483c87dc232a209 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 7.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 5.3E-82 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 Pfam PF00406 Adenylate kinase 5 190 2.3E-60 T 28-03-2018 CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 Pfam PF05191 Adenylate kinase, active site lid 127 162 4.9E-18 T 28-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 SUPERFAMILY SSF52540 1 214 6.5E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 Hamap MF_00235 Adenylate kinase [adk]. 1 213 52.868 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 Gene3D G3DSA:3.40.50.300 1 216 4.6E-68 T 28-03-2018 CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 PRINTS PR00094 Adenylate kinase signature 177 191 1.7E-32 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 PRINTS PR00094 Adenylate kinase signature 4 17 1.7E-32 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 PRINTS PR00094 Adenylate kinase signature 32 46 1.7E-32 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 PRINTS PR00094 Adenylate kinase signature 160 175 1.7E-32 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR44_RS00690 ff5037af50d5875af42cceb1df432ca7 216 PRINTS PR00094 Adenylate kinase signature 81 97 1.7E-32 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CWR44_RS04265 2b5def4cd16eb617d98d10ba80c1e361 142 SUPERFAMILY SSF54593 4 139 8.11E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS04265 2b5def4cd16eb617d98d10ba80c1e361 142 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 27 135 9.2E-6 T 28-03-2018 IPR028973 PhnB-like CWR44_RS04265 2b5def4cd16eb617d98d10ba80c1e361 142 Gene3D G3DSA:3.10.180.10 1 142 1.1E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS07570 3cead8987e06b8adb48bd698c9636c3e 256 Gene3D G3DSA:3.40.50.720 1 256 8.6E-43 T 28-03-2018 CWR44_RS07570 3cead8987e06b8adb48bd698c9636c3e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS07570 3cead8987e06b8adb48bd698c9636c3e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS07570 3cead8987e06b8adb48bd698c9636c3e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS07570 3cead8987e06b8adb48bd698c9636c3e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS07570 3cead8987e06b8adb48bd698c9636c3e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS07570 3cead8987e06b8adb48bd698c9636c3e 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 1.6E-80 T 28-03-2018 CWR44_RS07570 3cead8987e06b8adb48bd698c9636c3e 256 PIRSF PIRSF000094 1 256 1.7E-92 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWR44_RS07570 3cead8987e06b8adb48bd698c9636c3e 256 SUPERFAMILY SSF51735 5 254 1.51E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 SUPERFAMILY SSF54211 6 174 3.19E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 PIRSF PIRSF000676 1 301 5.6E-86 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 Gene3D G3DSA:3.30.70.890 166 290 6.5E-21 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 Gene3D G3DSA:3.30.230.10 4 165 8.2E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 Pfam PF08544 GHMP kinases C terminal 208 281 1.6E-8 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 PRINTS PR00958 Homoserine kinase signature 250 265 1.2E-36 T 28-03-2018 CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 PRINTS PR00958 Homoserine kinase signature 12 27 1.2E-36 T 28-03-2018 CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 PRINTS PR00958 Homoserine kinase signature 130 143 1.2E-36 T 28-03-2018 CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 PRINTS PR00958 Homoserine kinase signature 170 187 1.2E-36 T 28-03-2018 CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 PRINTS PR00958 Homoserine kinase signature 96 111 1.2E-36 T 28-03-2018 CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 89 100 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 Pfam PF00288 GHMP kinases N terminal domain 83 143 1.5E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 TIGRFAM TIGR00191 thrB: homoserine kinase 6 293 2.1E-79 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 SUPERFAMILY SSF55060 166 285 1.81E-33 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS09345 a21fd7000a99317583fe8dab914629dc 305 Hamap MF_00384 Homoserine kinase [thrB]. 5 299 30.365 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CWR44_RS02520 21f31c4840885a0da683f217fd80f05c 531 Pfam PF00501 AMP-binding enzyme 21 423 3.5E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CWR44_RS02520 21f31c4840885a0da683f217fd80f05c 531 Gene3D G3DSA:3.30.300.30 417 530 2.4E-29 T 28-03-2018 CWR44_RS02520 21f31c4840885a0da683f217fd80f05c 531 Gene3D G3DSA:3.40.50.980 181 333 3.7E-37 T 28-03-2018 CWR44_RS02520 21f31c4840885a0da683f217fd80f05c 531 Gene3D G3DSA:2.30.38.10 334 416 1.2E-21 T 28-03-2018 CWR44_RS02520 21f31c4840885a0da683f217fd80f05c 531 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 28-03-2018 IPR020845 AMP-binding, conserved site CWR44_RS02520 21f31c4840885a0da683f217fd80f05c 531 SUPERFAMILY SSF56801 17 522 2.88E-140 T 28-03-2018 CWR44_RS02520 21f31c4840885a0da683f217fd80f05c 531 Gene3D G3DSA:3.40.50.980 9 180 1.5E-33 T 28-03-2018 CWR44_RS02520 21f31c4840885a0da683f217fd80f05c 531 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 510 1.3E-23 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 Pfam PF01479 S4 domain 365 400 2.4E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 3 419 45.568 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 SUPERFAMILY SSF52374 5 324 3.6E-111 T 28-03-2018 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 51 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 419 1.2E-133 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 1.1E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 1.1E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 1.1E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 45 67 1.1E-30 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 Gene3D G3DSA:3.40.50.620 3 224 6.1E-70 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 SMART SM00363 353 415 1.2E-4 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 Gene3D G3DSA:3.10.290.10 326 420 1.3E-21 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 SUPERFAMILY SSF55174 322 419 4.45E-22 T 28-03-2018 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 Pfam PF00579 tRNA synthetases class I (W and Y) 30 324 2.0E-84 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11520 92c483f66f15b4971c0c8c627f1ff079 420 Gene3D G3DSA:1.10.240.10 225 325 9.2E-37 T 28-03-2018 CWR44_RS02175 60ed0ec40790e7effe2cb4263b180253 128 Pfam PF03788 LrgA family 22 113 1.2E-23 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 CWR44_RS10360 ce953b2556e4b314654fcb2e8610dacd 542 SMART SM00257 493 541 3.3E-5 T 28-03-2018 IPR018392 LysM domain CWR44_RS10360 ce953b2556e4b314654fcb2e8610dacd 542 SUPERFAMILY SSF54106 492 541 1.57E-5 T 28-03-2018 IPR018392 LysM domain CWR44_RS10360 ce953b2556e4b314654fcb2e8610dacd 542 Pfam PF01476 LysM domain 494 541 3.9E-6 T 28-03-2018 IPR018392 LysM domain CWR44_RS10360 ce953b2556e4b314654fcb2e8610dacd 542 Gene3D G3DSA:3.10.350.10 490 542 2.6E-9 T 28-03-2018 CWR44_RS09630 9db0e705147177d3386124190a83103a 164 SUPERFAMILY SSF46689 17 86 1.25E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS09630 9db0e705147177d3386124190a83103a 164 Gene3D G3DSA:1.10.10.10 43 95 0.0014 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS09630 9db0e705147177d3386124190a83103a 164 Gene3D G3DSA:1.10.10.60 1 42 4.5E-7 T 28-03-2018 CWR44_RS12650 fd006717fbac6aa2f349d9c98ed270fa 427 Gene3D G3DSA:1.10.287.130 211 271 8.0E-10 T 28-03-2018 CWR44_RS12650 fd006717fbac6aa2f349d9c98ed270fa 427 Pfam PF14501 GHKL domain 321 424 2.1E-17 T 28-03-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain CWR44_RS12650 fd006717fbac6aa2f349d9c98ed270fa 427 Gene3D G3DSA:3.30.565.10 275 414 4.9E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS12650 fd006717fbac6aa2f349d9c98ed270fa 427 SUPERFAMILY SSF55874 290 406 7.41E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS10870 9d6e48c0ba5d8255f9deebdfb9f28324 234 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 172 233 2.8E-20 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CWR44_RS10870 9d6e48c0ba5d8255f9deebdfb9f28324 234 SUPERFAMILY SSF47781 154 233 1.45E-28 T 28-03-2018 IPR010994 RuvA domain 2-like CWR44_RS10870 9d6e48c0ba5d8255f9deebdfb9f28324 234 Pfam PF12836 Helix-hairpin-helix motif 170 233 2.3E-24 T 28-03-2018 CWR44_RS10870 9d6e48c0ba5d8255f9deebdfb9f28324 234 SMART SM00278 212 231 0.012 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS10870 9d6e48c0ba5d8255f9deebdfb9f28324 234 SMART SM00278 182 201 0.08 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CWR44_RS10870 9d6e48c0ba5d8255f9deebdfb9f28324 234 Gene3D G3DSA:1.10.150.280 129 234 7.0E-28 T 28-03-2018 CWR44_RS03845 c977846b197c6774584db5f6fcce58f4 517 Gene3D G3DSA:3.40.190.10 146 285 7.3E-23 T 28-03-2018 CWR44_RS03845 c977846b197c6774584db5f6fcce58f4 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 435 1.3E-67 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CWR44_RS03845 c977846b197c6774584db5f6fcce58f4 517 Gene3D G3DSA:3.90.76.10 45 145 1.8E-25 T 28-03-2018 CWR44_RS03845 c977846b197c6774584db5f6fcce58f4 517 Gene3D G3DSA:3.10.105.10 286 485 1.6E-39 T 28-03-2018 CWR44_RS03845 c977846b197c6774584db5f6fcce58f4 517 PIRSF PIRSF002741 2 517 1.6E-61 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CWR44_RS03845 c977846b197c6774584db5f6fcce58f4 517 SUPERFAMILY SSF53850 48 510 2.3E-93 T 28-03-2018 CWR44_RS10795 1e7053b53535570a770199011f1a890a 236 Gene3D G3DSA:2.40.50.140 171 236 1.6E-9 T 28-03-2018 CWR44_RS10795 1e7053b53535570a770199011f1a890a 236 SUPERFAMILY SSF141322 171 234 2.09E-5 T 28-03-2018 CWR44_RS11515 ed84e0ffc4bcab71e55bf0e410bb3ef6 156 Pfam PF01047 MarR family 38 93 1.7E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS11515 ed84e0ffc4bcab71e55bf0e410bb3ef6 156 SUPERFAMILY SSF46785 9 151 8.04E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11515 ed84e0ffc4bcab71e55bf0e410bb3ef6 156 SMART SM00347 28 131 7.2E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS11515 ed84e0ffc4bcab71e55bf0e410bb3ef6 156 Gene3D G3DSA:1.10.10.10 2 155 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01445 5f369b69ff5d77afc160d8c70cbebd27 140 Gene3D G3DSA:2.30.110.10 2 133 4.9E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR44_RS01445 5f369b69ff5d77afc160d8c70cbebd27 140 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 7 123 2.4E-16 T 28-03-2018 CWR44_RS01445 5f369b69ff5d77afc160d8c70cbebd27 140 SUPERFAMILY SSF50475 6 129 1.38E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CWR44_RS02510 65c2e3a077ee736f397b74f2f9f73564 131 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.6E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS02510 65c2e3a077ee736f397b74f2f9f73564 131 SUPERFAMILY SSF46785 2 85 3.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02510 65c2e3a077ee736f397b74f2f9f73564 131 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.1E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS02510 65c2e3a077ee736f397b74f2f9f73564 131 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.1E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS02510 65c2e3a077ee736f397b74f2f9f73564 131 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.1E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS02510 65c2e3a077ee736f397b74f2f9f73564 131 Gene3D G3DSA:1.10.10.10 1 94 1.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04445 930855b479c92d011efca58e325859de 451 Gene3D G3DSA:1.10.8.60 280 351 4.1E-32 T 28-03-2018 CWR44_RS04445 930855b479c92d011efca58e325859de 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 211 225 4.1E-53 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWR44_RS04445 930855b479c92d011efca58e325859de 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 147 167 4.1E-53 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWR44_RS04445 930855b479c92d011efca58e325859de 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 179 193 4.1E-53 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWR44_RS04445 930855b479c92d011efca58e325859de 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 408 427 4.1E-53 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWR44_RS04445 930855b479c92d011efca58e325859de 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 245 272 4.1E-53 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CWR44_RS04445 930855b479c92d011efca58e325859de 451 Gene3D G3DSA:3.40.50.300 111 278 1.2E-21 T 28-03-2018 CWR44_RS04445 930855b479c92d011efca58e325859de 451 Pfam PF11638 DnaA N-terminal domain 4 66 6.3E-11 T 28-03-2018 IPR024633 DnaA N-terminal domain CWR44_RS04445 930855b479c92d011efca58e325859de 451 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 359 427 6.9E-31 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CWR44_RS04445 930855b479c92d011efca58e325859de 451 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 7 448 1.1E-182 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CWR44_RS04445 930855b479c92d011efca58e325859de 451 ProSitePatterns PS01008 DnaA protein signature. 408 427 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CWR44_RS04445 930855b479c92d011efca58e325859de 451 SUPERFAMILY SSF52540 114 325 6.41E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04445 930855b479c92d011efca58e325859de 451 SMART SM00760 358 427 4.4E-41 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CWR44_RS04445 930855b479c92d011efca58e325859de 451 Gene3D G3DSA:1.10.1750.10 352 449 1.2E-36 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CWR44_RS04445 930855b479c92d011efca58e325859de 451 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 4 449 33.964 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CWR44_RS04445 930855b479c92d011efca58e325859de 451 SUPERFAMILY SSF48295 345 450 1.36E-36 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CWR44_RS04445 930855b479c92d011efca58e325859de 451 SMART SM00382 146 277 3.9E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS04445 930855b479c92d011efca58e325859de 451 Pfam PF00308 Bacterial dnaA protein 115 331 2.2E-103 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 TIGRFAM TIGR00767 rho: transcription termination factor Rho 19 424 7.8E-187 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 426 199.016 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 Pfam PF07497 Rho termination factor, RNA-binding domain 63 136 3.2E-28 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 Pfam PF07498 Rho termination factor, N-terminal domain 19 59 7.9E-12 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 SUPERFAMILY SSF50249 62 135 2.78E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 167 372 1.5E-21 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 SMART SM00357 64 129 2.2E-13 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 Gene3D G3DSA:1.10.720.10 12 55 3.9E-10 T 28-03-2018 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 SMART SM00382 178 364 3.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 SUPERFAMILY SSF68912 19 59 8.24E-7 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 Gene3D G3DSA:3.40.50.300 140 426 1.3E-49 T 28-03-2018 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 SMART SM00959 17 59 1.8E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 Gene3D G3DSA:2.40.50.140 62 127 8.5E-27 T 28-03-2018 CWR44_RS00235 015ad322ba784ff6298d00a2234fa442 438 SUPERFAMILY SSF52540 101 380 1.32E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04905 cda29e5f1aedddbf34643a3f694efb75 193 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 2 190 3.7E-94 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CWR44_RS04905 cda29e5f1aedddbf34643a3f694efb75 193 Gene3D G3DSA:3.40.50.2020 3 188 4.9E-21 T 28-03-2018 CWR44_RS04905 cda29e5f1aedddbf34643a3f694efb75 193 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 39.236 T 28-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CWR44_RS04905 cda29e5f1aedddbf34643a3f694efb75 193 SUPERFAMILY SSF53271 2 186 5.38E-40 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWR44_RS08535 9b48b8644bf9adc0f03dd9b41a7f9ff6 552 Pfam PF02734 DAK2 domain 35 199 9.6E-41 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWR44_RS08535 9b48b8644bf9adc0f03dd9b41a7f9ff6 552 SMART SM01121 236 552 6.8E-183 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CWR44_RS08535 9b48b8644bf9adc0f03dd9b41a7f9ff6 552 SUPERFAMILY SSF101473 3 200 1.01E-46 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWR44_RS08535 9b48b8644bf9adc0f03dd9b41a7f9ff6 552 Pfam PF13684 Dihydroxyacetone kinase family 236 552 1.1E-118 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CWR44_RS08535 9b48b8644bf9adc0f03dd9b41a7f9ff6 552 SMART SM01120 35 200 5.1E-72 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWR44_RS08535 9b48b8644bf9adc0f03dd9b41a7f9ff6 552 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 10 552 4.0E-211 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV CWR44_RS04075 b1c2c96403220b09e58058898e02ca94 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 1.3E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS04075 b1c2c96403220b09e58058898e02ca94 438 Pfam PF01610 Transposase 164 417 3.8E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS11720 86aac286788b44cfdcb99b209398981b 152 Gene3D G3DSA:3.40.50.960 1 66 2.0E-24 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11720 86aac286788b44cfdcb99b209398981b 152 Gene3D G3DSA:3.40.50.960 67 152 9.5E-40 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11720 86aac286788b44cfdcb99b209398981b 152 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 149 7.6E-60 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11720 86aac286788b44cfdcb99b209398981b 152 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 12 148 8.9E-59 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11720 86aac286788b44cfdcb99b209398981b 152 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 7 152 31.415 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS11720 86aac286788b44cfdcb99b209398981b 152 SUPERFAMILY SSF52121 3 152 7.06E-63 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 Gene3D G3DSA:1.20.58.410 567 647 3.7E-7 T 28-03-2018 CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 ProSitePatterns PS00211 ABC transporters family signature. 447 461 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 SMART SM00382 354 520 2.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 SMART SM00382 28 249 1.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 Pfam PF16326 ABC transporter C-terminal domain 575 645 6.6E-12 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 Gene3D G3DSA:3.40.50.300 2 276 1.9E-56 T 28-03-2018 CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 Gene3D G3DSA:3.40.50.300 292 559 5.9E-52 T 28-03-2018 CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 SUPERFAMILY SSF52540 4 249 1.92E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 Pfam PF12848 ABC transporter 237 320 1.2E-22 T 28-03-2018 IPR032781 ABC-transporter extension domain CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 Pfam PF00005 ABC transporter 20 195 1.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 Pfam PF00005 ABC transporter 347 475 1.8E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS12695 fac7f6379ed8f61dc154fa77e64ba4e3 647 SUPERFAMILY SSF52540 318 536 5.11E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00605 aec9a21f649ab412cc7bf246127b2eab 310 Pfam PF00294 pfkB family carbohydrate kinase 10 292 1.5E-57 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CWR44_RS00605 aec9a21f649ab412cc7bf246127b2eab 310 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR44_RS00605 aec9a21f649ab412cc7bf246127b2eab 310 TIGRFAM TIGR01231 lacC: tagatose-6-phosphate kinase 1 310 6.8E-151 T 28-03-2018 IPR005926 Tagatose-6-phosphate kinase GO:0009024|GO:0019512 KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CWR44_RS00605 aec9a21f649ab412cc7bf246127b2eab 310 Hamap MF_01557 Tagatose-6-phosphate kinase [lacC]. 1 310 57.159 T 28-03-2018 IPR005926 Tagatose-6-phosphate kinase GO:0009024|GO:0019512 KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395 CWR44_RS00605 aec9a21f649ab412cc7bf246127b2eab 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 248 261 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR44_RS00605 aec9a21f649ab412cc7bf246127b2eab 310 Gene3D G3DSA:2.20.150.10 9 42 1.1E-14 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CWR44_RS00605 aec9a21f649ab412cc7bf246127b2eab 310 SUPERFAMILY SSF53613 1 289 6.55E-63 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS00605 aec9a21f649ab412cc7bf246127b2eab 310 PIRSF PIRSF000535 1 310 7.5E-126 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWR44_RS00605 aec9a21f649ab412cc7bf246127b2eab 310 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 307 1.8E-97 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWR44_RS00605 aec9a21f649ab412cc7bf246127b2eab 310 Gene3D G3DSA:3.40.1190.20 43 310 3.6E-39 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS11670 543ad550fd033a48d567659d88e57fd5 103 SUPERFAMILY SSF52821 2 99 5.37E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS11670 543ad550fd033a48d567659d88e57fd5 103 Pfam PF00581 Rhodanese-like domain 6 94 2.3E-10 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS11670 543ad550fd033a48d567659d88e57fd5 103 Gene3D G3DSA:3.40.250.10 1 102 5.9E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS11670 543ad550fd033a48d567659d88e57fd5 103 SMART SM00450 5 99 1.4E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS11450 34ca7b44d69d8bd513d184225d390075 564 Gene3D G3DSA:1.20.120.20 99 500 0.002 T 28-03-2018 CWR44_RS11450 34ca7b44d69d8bd513d184225d390075 564 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 3 564 20.608 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CWR44_RS11450 34ca7b44d69d8bd513d184225d390075 564 Pfam PF06160 Septation ring formation regulator, EzrA 6 560 2.4E-157 T 28-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CWR44_RS07520 b94ecf811e47afbe235f3d97eaeb5887 602 Pfam PF08439 Oligopeptidase F 117 186 3.5E-21 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CWR44_RS07520 b94ecf811e47afbe235f3d97eaeb5887 602 Pfam PF01432 Peptidase family M3 207 587 4.1E-76 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CWR44_RS07520 b94ecf811e47afbe235f3d97eaeb5887 602 SUPERFAMILY SSF55486 13 585 2.2E-124 T 28-03-2018 CWR44_RS07520 b94ecf811e47afbe235f3d97eaeb5887 602 Gene3D G3DSA:1.10.1370.10 96 599 8.4E-46 T 28-03-2018 CWR44_RS07520 b94ecf811e47afbe235f3d97eaeb5887 602 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 16 598 1.6E-202 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CWR44_RS05960 a901aa2d12f72f49738dc2e407b99237 67 PIRSF PIRSF002599 1 67 4.9E-24 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CWR44_RS05960 a901aa2d12f72f49738dc2e407b99237 67 SMART SM00357 3 66 4.1E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CWR44_RS05960 a901aa2d12f72f49738dc2e407b99237 67 PRINTS PR00050 Cold shock protein signature 39 57 2.8E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR44_RS05960 a901aa2d12f72f49738dc2e407b99237 67 PRINTS PR00050 Cold shock protein signature 24 33 2.8E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR44_RS05960 a901aa2d12f72f49738dc2e407b99237 67 PRINTS PR00050 Cold shock protein signature 4 19 2.8E-19 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR44_RS05960 a901aa2d12f72f49738dc2e407b99237 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CWR44_RS05960 a901aa2d12f72f49738dc2e407b99237 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 6.3E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CWR44_RS05960 a901aa2d12f72f49738dc2e407b99237 67 SUPERFAMILY SSF50249 1 66 2.02E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS05960 a901aa2d12f72f49738dc2e407b99237 67 Gene3D G3DSA:2.40.50.140 1 66 5.2E-26 T 28-03-2018 CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 SUPERFAMILY SSF47413 2 59 5.63E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 SUPERFAMILY SSF53822 58 311 7.28E-56 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 1.4E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 1.4E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 Gene3D G3DSA:3.40.50.2300 58 163 3.8E-21 T 28-03-2018 CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 Pfam PF13377 Periplasmic binding protein-like domain 173 318 1.5E-25 T 28-03-2018 CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.4E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 SMART SM00354 1 71 2.4E-35 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 Gene3D G3DSA:1.10.260.40 3 57 5.5E-22 T 28-03-2018 CWR44_RS03705 c91283543d5eabcf52a1ba7e5d66e133 322 Gene3D G3DSA:3.40.50.2300 164 321 3.4E-35 T 28-03-2018 CWR44_RS07630 1dbd0f08d0bf653f23ee59e422f23a39 503 ProSitePatterns PS00785 5'-nucleotidase signature 1. 9 21 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07630 1dbd0f08d0bf653f23ee59e422f23a39 503 SUPERFAMILY SSF56300 3 303 1.92E-56 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS07630 1dbd0f08d0bf653f23ee59e422f23a39 503 PRINTS PR01607 Apyrase family signature 217 240 1.7E-8 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07630 1dbd0f08d0bf653f23ee59e422f23a39 503 PRINTS PR01607 Apyrase family signature 7 25 1.7E-8 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07630 1dbd0f08d0bf653f23ee59e422f23a39 503 PRINTS PR01607 Apyrase family signature 184 201 1.7E-8 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07630 1dbd0f08d0bf653f23ee59e422f23a39 503 PRINTS PR01607 Apyrase family signature 363 386 1.7E-8 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07630 1dbd0f08d0bf653f23ee59e422f23a39 503 Gene3D G3DSA:3.90.780.10 307 493 1.9E-16 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07630 1dbd0f08d0bf653f23ee59e422f23a39 503 Gene3D G3DSA:3.60.21.10 3 306 4.0E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS07630 1dbd0f08d0bf653f23ee59e422f23a39 503 Pfam PF02872 5'-nucleotidase, C-terminal domain 326 457 9.3E-12 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07630 1dbd0f08d0bf653f23ee59e422f23a39 503 SUPERFAMILY SSF55816 324 467 7.59E-18 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 Gene3D G3DSA:3.90.1170.30 1 44 1.8E-13 T 28-03-2018 CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 SUPERFAMILY SSF47005 142 181 5.23E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 Pfam PF02817 e3 binding domain 144 177 4.6E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 Gene3D G3DSA:3.90.1170.30 45 95 8.7E-5 T 28-03-2018 CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 Pfam PF00364 Biotin-requiring enzyme 2 74 2.3E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 213 434 1.6E-78 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 Gene3D G3DSA:4.10.320.10 140 188 3.5E-15 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 SUPERFAMILY SSF51230 2 83 5.1E-26 T 28-03-2018 IPR011053 Single hybrid motif CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 SUPERFAMILY SSF52777 214 434 2.36E-79 T 28-03-2018 CWR44_RS10500 e123f428c58a92550f50d0eb66dac91c 442 Gene3D G3DSA:3.30.559.10 195 439 5.4E-83 T 28-03-2018 CWR44_RS01040 8ef4533d2dec64ca721df061056724c9 259 SMART SM00047 102 250 1.6E-42 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR44_RS01040 8ef4533d2dec64ca721df061056724c9 259 Gene3D G3DSA:1.10.530.10 98 247 1.7E-24 T 28-03-2018 CWR44_RS01040 8ef4533d2dec64ca721df061056724c9 259 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 115 242 1.3E-14 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR44_RS12455 02c1b00a1556daf3db4f644aa7262b18 266 Gene3D G3DSA:3.40.190.10 93 164 8.4E-14 T 28-03-2018 CWR44_RS12455 02c1b00a1556daf3db4f644aa7262b18 266 Pfam PF00800 Prephenate dehydratase 4 177 3.7E-42 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CWR44_RS12455 02c1b00a1556daf3db4f644aa7262b18 266 SUPERFAMILY SSF55021 170 265 7.63E-20 T 28-03-2018 CWR44_RS12455 02c1b00a1556daf3db4f644aa7262b18 266 Gene3D G3DSA:3.40.190.10 1 92 2.8E-23 T 28-03-2018 CWR44_RS12455 02c1b00a1556daf3db4f644aa7262b18 266 SUPERFAMILY SSF53850 1 180 1.85E-49 T 28-03-2018 CWR44_RS12455 02c1b00a1556daf3db4f644aa7262b18 266 Gene3D G3DSA:3.30.70.260 178 266 7.0E-17 T 28-03-2018 CWR44_RS13175 8297ee2a0b605822bdbb1ca344d8b793 69 Gene3D G3DSA:3.30.70.100 1 69 2.5E-21 T 28-03-2018 CWR44_RS13175 8297ee2a0b605822bdbb1ca344d8b793 69 PRINTS PR00944 Copper ion binding protein signature 54 67 2.3E-5 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR44_RS13175 8297ee2a0b605822bdbb1ca344d8b793 69 PRINTS PR00944 Copper ion binding protein signature 15 28 2.3E-5 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR44_RS13175 8297ee2a0b605822bdbb1ca344d8b793 69 PRINTS PR00944 Copper ion binding protein signature 3 15 2.3E-5 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR44_RS13175 8297ee2a0b605822bdbb1ca344d8b793 69 PRINTS PR00944 Copper ion binding protein signature 28 41 2.3E-5 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR44_RS13175 8297ee2a0b605822bdbb1ca344d8b793 69 Pfam PF00403 Heavy-metal-associated domain 5 66 1.2E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS13175 8297ee2a0b605822bdbb1ca344d8b793 69 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 6 67 1.1E-20 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CWR44_RS13175 8297ee2a0b605822bdbb1ca344d8b793 69 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CWR44_RS13175 8297ee2a0b605822bdbb1ca344d8b793 69 SUPERFAMILY SSF55008 5 68 9.16E-21 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS07105 e60a45cc5d538ca7df47224642e4d02a 98 SUPERFAMILY SSF52833 7 98 1.86E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS07105 e60a45cc5d538ca7df47224642e4d02a 98 Pfam PF00085 Thioredoxin 15 84 1.3E-6 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWR44_RS07105 e60a45cc5d538ca7df47224642e4d02a 98 Gene3D G3DSA:3.40.30.10 18 98 1.6E-8 T 28-03-2018 CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 Gene3D G3DSA:2.40.50.140 65 126 2.4E-25 T 28-03-2018 CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 Gene3D G3DSA:2.30.30.30 2 61 4.5E-27 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 2.7E-23 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 PIRSF PIRSF005901 1 185 4.0E-72 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.1E-80 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 SMART SM00841 129 184 9.2E-33 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 Gene3D G3DSA:2.40.50.140 129 184 3.8E-27 T 28-03-2018 CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 SUPERFAMILY SSF50249 65 129 7.28E-21 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 SUPERFAMILY SSF50249 128 185 4.45E-18 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 SUPERFAMILY SSF50104 1 63 6.62E-22 T 28-03-2018 IPR008991 Translation protein SH3-like domain CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.9E-27 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.7E-26 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 SMART SM01185 67 121 3.1E-27 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CWR44_RS10565 b2d2c7fb5714d6e8a90c745fde723578 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 50.951 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CWR44_RS02310 4711435e75fcf8aab48a294c0723b8cc 474 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 245 465 1.5E-80 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related CWR44_RS02310 4711435e75fcf8aab48a294c0723b8cc 474 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 4 213 7.2E-24 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related CWR44_RS02310 4711435e75fcf8aab48a294c0723b8cc 474 SUPERFAMILY SSF52540 274 464 2.57E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS02310 4711435e75fcf8aab48a294c0723b8cc 474 Gene3D G3DSA:3.40.50.300 1 230 1.6E-39 T 28-03-2018 CWR44_RS02310 4711435e75fcf8aab48a294c0723b8cc 474 Gene3D G3DSA:3.40.50.300 231 470 5.4E-83 T 28-03-2018 CWR44_RS02310 4711435e75fcf8aab48a294c0723b8cc 474 SUPERFAMILY SSF52540 25 213 8.04E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00985 c21bd86e1b4bcd71c8eb2eba704c7c5a 286 Gene3D G3DSA:2.60.120.10 15 200 3.9E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWR44_RS00985 c21bd86e1b4bcd71c8eb2eba704c7c5a 286 SUPERFAMILY SSF46689 202 254 2.46E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS00985 c21bd86e1b4bcd71c8eb2eba704c7c5a 286 Pfam PF12833 Helix-turn-helix domain 171 250 7.1E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS00985 c21bd86e1b4bcd71c8eb2eba704c7c5a 286 SMART SM00342 165 249 5.9E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS00985 c21bd86e1b4bcd71c8eb2eba704c7c5a 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 218 233 9.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR44_RS00985 c21bd86e1b4bcd71c8eb2eba704c7c5a 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 233 249 9.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR44_RS00985 c21bd86e1b4bcd71c8eb2eba704c7c5a 286 Gene3D G3DSA:1.10.10.60 201 258 4.6E-8 T 28-03-2018 CWR44_RS00320 b9beec445e31702b2960c8a0cfef15a6 220 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 212 1.8E-88 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWR44_RS00320 b9beec445e31702b2960c8a0cfef15a6 220 Gene3D G3DSA:3.20.20.70 1 216 1.1E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS00320 b9beec445e31702b2960c8a0cfef15a6 220 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 215 37.819 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CWR44_RS00320 b9beec445e31702b2960c8a0cfef15a6 220 SMART SM01133 2 213 3.0E-102 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWR44_RS00320 b9beec445e31702b2960c8a0cfef15a6 220 PIRSF PIRSF001357 1 219 5.9E-78 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWR44_RS00320 b9beec445e31702b2960c8a0cfef15a6 220 Pfam PF01791 DeoC/LacD family aldolase 6 208 1.5E-23 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CWR44_RS00320 b9beec445e31702b2960c8a0cfef15a6 220 SUPERFAMILY SSF51569 1 214 1.78E-84 T 28-03-2018 CWR44_RS00045 6d626e0f4437db38be8c30b7555ffa00 399 Pfam PF01098 Cell cycle protein 17 388 1.9E-95 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CWR44_RS12875 6d626e0f4437db38be8c30b7555ffa00 399 Pfam PF01098 Cell cycle protein 17 388 1.9E-95 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CWR44_RS13105 2691f3a1122a2acbb80754cbdf920db2 75 SMART SM00899 2 75 2.2E-11 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR44_RS13105 2691f3a1122a2acbb80754cbdf920db2 75 Gene3D G3DSA:2.30.30.90 1 75 8.5E-11 T 28-03-2018 CWR44_RS13105 2691f3a1122a2acbb80754cbdf920db2 75 SUPERFAMILY SSF50037 7 74 1.65E-12 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CWR44_RS13105 2691f3a1122a2acbb80754cbdf920db2 75 Pfam PF04023 FeoA domain 5 74 2.1E-12 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CWR44_RS12710 8a4bb65bd98cbf29e44289e85e1209ca 221 SUPERFAMILY SSF53067 3 103 2.42E-28 T 28-03-2018 CWR44_RS12710 8a4bb65bd98cbf29e44289e85e1209ca 221 Pfam PF00814 Glycoprotease family 24 149 3.4E-33 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CWR44_RS12710 8a4bb65bd98cbf29e44289e85e1209ca 221 SUPERFAMILY SSF53067 109 204 1.23E-12 T 28-03-2018 CWR44_RS12710 8a4bb65bd98cbf29e44289e85e1209ca 221 Gene3D G3DSA:3.30.420.40 1 138 6.9E-37 T 28-03-2018 CWR44_RS12710 8a4bb65bd98cbf29e44289e85e1209ca 221 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 205 1.3E-54 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 Gene3D G3DSA:3.40.50.1980 21 187 8.0E-48 T 28-03-2018 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 SUPERFAMILY SSF53807 12 308 2.21E-86 T 28-03-2018 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00690 Adhesin family signature 248 266 8.6E-50 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00690 Adhesin family signature 274 293 8.6E-50 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00690 Adhesin family signature 76 93 8.6E-50 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00690 Adhesin family signature 63 76 8.6E-50 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00690 Adhesin family signature 32 50 8.6E-50 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00690 Adhesin family signature 195 216 8.6E-50 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 Gene3D G3DSA:3.40.50.1980 188 308 1.1E-32 T 28-03-2018 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00691 Adhesin B signature 76 95 3.9E-78 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00691 Adhesin B signature 287 305 3.9E-78 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00691 Adhesin B signature 32 53 3.9E-78 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00691 Adhesin B signature 137 156 3.9E-78 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00691 Adhesin B signature 266 284 3.9E-78 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00691 Adhesin B signature 195 212 3.9E-78 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00691 Adhesin B signature 221 239 3.9E-78 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00691 Adhesin B signature 244 261 3.9E-78 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 PRINTS PR00691 Adhesin B signature 57 75 3.9E-78 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03880 a0c908c7699fcb5f48a05608d2b94655 309 Pfam PF01297 Zinc-uptake complex component A periplasmic 35 305 4.6E-74 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CWR44_RS07235 3f8fc646601d7aaa130dc917b322d63f 78 Pfam PF00550 Phosphopantetheine attachment site 5 74 8.0E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWR44_RS07235 3f8fc646601d7aaa130dc917b322d63f 78 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 4 76 1.3E-41 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CWR44_RS07235 3f8fc646601d7aaa130dc917b322d63f 78 SUPERFAMILY SSF47336 2 77 7.46E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWR44_RS07235 3f8fc646601d7aaa130dc917b322d63f 78 Gene3D G3DSA:1.10.1200.10 1 78 1.4E-10 T 28-03-2018 CWR44_RS07235 3f8fc646601d7aaa130dc917b322d63f 78 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 78 47.542 T 28-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 Gene3D G3DSA:3.30.300.10 389 513 9.2E-52 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 513 54.503 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 1.1E-7 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 1.1E-7 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.1E-7 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 Pfam PF00117 Glutamine amidotransferase class-I 12 190 1.7E-44 T 28-03-2018 IPR017926 Glutamine amidotransferase CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 Gene3D G3DSA:3.40.50.620 214 388 8.9E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 SUPERFAMILY SSF52317 6 228 4.4E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 1.7E-6 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 1.7E-6 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 1.7E-6 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 Gene3D G3DSA:3.40.50.880 5 213 1.3E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 SUPERFAMILY SSF52402 188 406 5.29E-62 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 Pfam PF00958 GMP synthase C terminal domain 422 512 4.9E-42 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 195 2.6E-81 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 513 6.0E-153 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 PRINTS PR00097 Anthranilate synthase component II signature 168 181 5.2E-6 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 PRINTS PR00097 Anthranilate synthase component II signature 54 63 5.2E-6 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 PRINTS PR00097 Anthranilate synthase component II signature 81 92 5.2E-6 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 SUPERFAMILY SSF54810 393 513 5.23E-49 T 28-03-2018 CWR44_RS04920 382a81d213980d442f7a6e93e7b8d0fb 513 Pfam PF03054 tRNA methyl transferase 220 249 2.0E-5 T 28-03-2018 CWR44_RS07590 7b5778be94a7bd35bafb2e5e96fd6aba 381 Gene3D G3DSA:1.20.1250.20 1 182 1.6E-16 T 28-03-2018 CWR44_RS07590 7b5778be94a7bd35bafb2e5e96fd6aba 381 PRINTS PR01035 Tetracycline resistance protein signature 321 343 5.2E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR44_RS07590 7b5778be94a7bd35bafb2e5e96fd6aba 381 PRINTS PR01035 Tetracycline resistance protein signature 202 218 5.2E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR44_RS07590 7b5778be94a7bd35bafb2e5e96fd6aba 381 Pfam PF07690 Major Facilitator Superfamily 2 336 1.6E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS07590 7b5778be94a7bd35bafb2e5e96fd6aba 381 Gene3D G3DSA:1.20.1250.20 191 380 7.5E-22 T 28-03-2018 CWR44_RS07590 7b5778be94a7bd35bafb2e5e96fd6aba 381 SUPERFAMILY SSF103473 3 377 4.19E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS06970 576f1cbc111385fcfdda531070830560 156 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 70.875 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWR44_RS06970 576f1cbc111385fcfdda531070830560 156 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 13 135 3.0E-59 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWR44_RS06970 576f1cbc111385fcfdda531070830560 156 Gene3D G3DSA:2.40.280.10 12 130 4.6E-50 T 28-03-2018 IPR023620 Small protein B CWR44_RS06970 576f1cbc111385fcfdda531070830560 156 SUPERFAMILY SSF74982 6 135 4.19E-51 T 28-03-2018 IPR023620 Small protein B CWR44_RS06970 576f1cbc111385fcfdda531070830560 156 ProSitePatterns PS01317 SsrA-binding protein. 30 42 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site CWR44_RS06970 576f1cbc111385fcfdda531070830560 156 Pfam PF01668 SmpB protein 13 153 7.2E-60 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWR44_RS06970 576f1cbc111385fcfdda531070830560 156 TIGRFAM TIGR00086 smpB: SsrA-binding protein 12 153 2.8E-57 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CWR44_RS02210 d4956651718095b2cf2a06094148e315 173 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 74 159 7.4E-29 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWR44_RS02210 d4956651718095b2cf2a06094148e315 173 SUPERFAMILY SSF46767 72 159 2.35E-25 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWR44_RS02210 d4956651718095b2cf2a06094148e315 173 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWR44_RS02210 d4956651718095b2cf2a06094148e315 173 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 3 66 2.2E-4 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWR44_RS02210 d4956651718095b2cf2a06094148e315 173 Gene3D G3DSA:1.10.10.10 69 160 2.6E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02210 d4956651718095b2cf2a06094148e315 173 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 73 157 7.0E-29 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CWR44_RS02210 d4956651718095b2cf2a06094148e315 173 SUPERFAMILY SSF53155 4 77 5.1E-14 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CWR44_RS02210 d4956651718095b2cf2a06094148e315 173 Gene3D G3DSA:3.30.160.70 1 68 1.7E-12 T 28-03-2018 CWR44_RS02210 d4956651718095b2cf2a06094148e315 173 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 158 36.049 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 SUPERFAMILY SSF53098 421 875 4.23E-101 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 SMART SM00481 336 403 3.9E-25 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Gene3D G3DSA:1.20.5.140 571 590 4.6E-14 T 28-03-2018 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Gene3D G3DSA:1.10.150.280 1373 1422 2.2E-7 T 28-03-2018 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 SUPERFAMILY SSF81585 1375 1422 2.35E-7 T 28-03-2018 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Pfam PF00929 Exonuclease 423 578 3.7E-43 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Pfam PF11490 DNA polymerase III polC-type N-terminus II 94 207 9.1E-18 T 28-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 SMART SM00479 421 587 1.6E-58 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Pfam PF14579 Helix-hairpin-helix motif 1349 1428 4.4E-9 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Pfam PF14480 DNA polymerase III polC-type N-terminus I 8 79 3.0E-14 T 28-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 415 636 8.9E-56 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 232 1436 0.0 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Pfam PF02811 PHP domain 337 695 1.4E-49 T 28-03-2018 IPR004013 PHP domain GO:0003824 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 824 1246 1.4E-96 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Gene3D G3DSA:3.30.420.10 417 570 3.5E-44 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1438 435.224 T 28-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Gene3D G3DSA:3.20.20.150 322 416 4.8E-4 T 28-03-2018 CWR44_RS08730 db7a9c16660e7b67ad52119936b48b9b 1438 Gene3D G3DSA:2.40.50.140 222 321 6.3E-16 T 28-03-2018 CWR44_RS08980 3bb42d59ed5a44219311d2f56a5b0c5e 63 Pfam PF01381 Helix-turn-helix 7 60 6.5E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS08980 3bb42d59ed5a44219311d2f56a5b0c5e 63 Gene3D G3DSA:1.10.3100.10 4 62 1.7E-13 T 28-03-2018 IPR027910 YdiL-like domain CWR44_RS08980 3bb42d59ed5a44219311d2f56a5b0c5e 63 SUPERFAMILY SSF47413 6 61 1.69E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS08980 3bb42d59ed5a44219311d2f56a5b0c5e 63 SMART SM00530 6 61 3.9E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS04395 8c3ba4fc04680f13e9e241012c46e507 322 PIRSF PIRSF000443 1 322 6.9E-79 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CWR44_RS04395 8c3ba4fc04680f13e9e241012c46e507 322 Gene3D G3DSA:3.40.50.1820 2 317 1.6E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS04395 8c3ba4fc04680f13e9e241012c46e507 322 SUPERFAMILY SSF53474 5 315 7.94E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS04395 8c3ba4fc04680f13e9e241012c46e507 322 Pfam PF00561 alpha/beta hydrolase fold 38 302 4.4E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS04010 de67dacae8e82f9dce4b1a8cc259c000 221 Gene3D G3DSA:3.40.50.720 2 218 8.2E-30 T 28-03-2018 CWR44_RS04010 de67dacae8e82f9dce4b1a8cc259c000 221 SUPERFAMILY SSF51735 1 208 9.83E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS04010 de67dacae8e82f9dce4b1a8cc259c000 221 Pfam PF13460 NAD(P)H-binding 7 194 1.5E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10765 a016b2ce1f38d7441edee14e5ea2c6f1 134 Gene3D G3DSA:3.40.140.10 2 134 2.9E-45 T 28-03-2018 CWR44_RS10765 a016b2ce1f38d7441edee14e5ea2c6f1 134 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 104 2.3E-15 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWR44_RS10765 a016b2ce1f38d7441edee14e5ea2c6f1 134 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 6 133 1.6E-49 T 28-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CWR44_RS10765 a016b2ce1f38d7441edee14e5ea2c6f1 134 SUPERFAMILY SSF53927 5 133 4.52E-44 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR44_RS00525 a4d31caa4ff55e2d8e55d4d0c1b32626 332 Gene3D G3DSA:3.40.50.1980 159 331 3.2E-33 T 28-03-2018 CWR44_RS00525 a4d31caa4ff55e2d8e55d4d0c1b32626 332 Gene3D G3DSA:3.40.50.1980 30 158 1.5E-29 T 28-03-2018 CWR44_RS00525 a4d31caa4ff55e2d8e55d4d0c1b32626 332 Pfam PF01497 Periplasmic binding protein 61 298 1.1E-32 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CWR44_RS00525 a4d31caa4ff55e2d8e55d4d0c1b32626 332 SUPERFAMILY SSF53807 44 322 4.71E-61 T 28-03-2018 CWR44_RS04525 a3935669bc7cdfce09c0b01abb8c6900 190 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 8 179 2.2E-49 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS04525 a3935669bc7cdfce09c0b01abb8c6900 190 SUPERFAMILY SSF51306 25 182 3.87E-47 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR44_RS04525 a3935669bc7cdfce09c0b01abb8c6900 190 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 1.6E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS04525 a3935669bc7cdfce09c0b01abb8c6900 190 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 75 87 1.6E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS04525 a3935669bc7cdfce09c0b01abb8c6900 190 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 25 41 1.6E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS04525 a3935669bc7cdfce09c0b01abb8c6900 190 ProSitePatterns PS00501 Signal peptidases I serine active site. 34 41 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CWR44_RS04525 a3935669bc7cdfce09c0b01abb8c6900 190 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CWR44_RS04525 a3935669bc7cdfce09c0b01abb8c6900 190 Gene3D G3DSA:2.10.109.10 21 189 8.0E-43 T 28-03-2018 CWR44_RS04525 a3935669bc7cdfce09c0b01abb8c6900 190 Pfam PF00717 Peptidase S24-like 31 99 1.5E-18 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR44_RS04525 a3935669bc7cdfce09c0b01abb8c6900 190 ProSitePatterns PS00760 Signal peptidases I lysine active site. 77 89 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CWR44_RS05070 8b9b99ffc41af124614a91a5080ee8dc 230 SUPERFAMILY SSF55729 24 197 2.98E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS05070 8b9b99ffc41af124614a91a5080ee8dc 230 Pfam PF13302 Acetyltransferase (GNAT) domain 35 173 7.7E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS05070 8b9b99ffc41af124614a91a5080ee8dc 230 Gene3D G3DSA:3.40.630.30 22 219 1.4E-23 T 28-03-2018 CWR44_RS08230 c2de3641ad33a4fb0a36328540c2d45c 438 Pfam PF01610 Transposase 164 417 3.6E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS08230 c2de3641ad33a4fb0a36328540c2d45c 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 4.3E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS06110 c2de3641ad33a4fb0a36328540c2d45c 438 Pfam PF01610 Transposase 164 417 3.6E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS06110 c2de3641ad33a4fb0a36328540c2d45c 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 4.3E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS07725 c2de3641ad33a4fb0a36328540c2d45c 438 Pfam PF01610 Transposase 164 417 3.6E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS07725 c2de3641ad33a4fb0a36328540c2d45c 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 4.3E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS06550 c2de3641ad33a4fb0a36328540c2d45c 438 Pfam PF01610 Transposase 164 417 3.6E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS06550 c2de3641ad33a4fb0a36328540c2d45c 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 4.3E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS12200 c2de3641ad33a4fb0a36328540c2d45c 438 Pfam PF01610 Transposase 164 417 3.6E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS12200 c2de3641ad33a4fb0a36328540c2d45c 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 4.3E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS06750 89ec08725eaba4cdb93a2b582a645b13 373 Pfam PF02595 Glycerate kinase family 3 339 2.3E-54 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR44_RS06750 89ec08725eaba4cdb93a2b582a645b13 373 SUPERFAMILY SSF110738 1 367 1.7E-89 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR44_RS06750 89ec08725eaba4cdb93a2b582a645b13 373 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 339 1.2E-53 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR44_RS06750 89ec08725eaba4cdb93a2b582a645b13 373 Gene3D G3DSA:3.90.1510.10 43 271 1.5E-36 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CWR44_RS03860 e2d141c5f81e6ded4fa92fa3d03a3d07 452 Pfam PF05525 Branched-chain amino acid transport protein 8 441 1.2E-147 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWR44_RS03860 e2d141c5f81e6ded4fa92fa3d03a3d07 452 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 429 9.0E-123 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWR44_RS08700 1c770058504c5bd937be42261cf6a51b 240 Pfam PF00696 Amino acid kinase family 8 217 1.0E-26 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR44_RS08700 1c770058504c5bd937be42261cf6a51b 240 SUPERFAMILY SSF53633 6 239 8.25E-73 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CWR44_RS08700 1c770058504c5bd937be42261cf6a51b 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 5 239 43.225 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CWR44_RS08700 1c770058504c5bd937be42261cf6a51b 240 PIRSF PIRSF005650 2 240 6.7E-94 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CWR44_RS08700 1c770058504c5bd937be42261cf6a51b 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 7 239 2.0E-103 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CWR44_RS08700 1c770058504c5bd937be42261cf6a51b 240 Gene3D G3DSA:3.40.1160.10 1 240 8.1E-42 T 28-03-2018 CWR44_RS10935 32c475fc502ad8547c59f704568950cf 149 Gene3D G3DSA:2.40.50.100 63 149 5.1E-14 T 28-03-2018 CWR44_RS10935 32c475fc502ad8547c59f704568950cf 149 SUPERFAMILY SSF51230 74 148 6.41E-19 T 28-03-2018 IPR011053 Single hybrid motif CWR44_RS10935 32c475fc502ad8547c59f704568950cf 149 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 105 122 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR44_RS10935 32c475fc502ad8547c59f704568950cf 149 Pfam PF00364 Biotin-requiring enzyme 73 148 2.2E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CWR44_RS10935 32c475fc502ad8547c59f704568950cf 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 110 123 6.3E-5 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWR44_RS10935 32c475fc502ad8547c59f704568950cf 149 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 77 90 6.3E-5 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CWR44_RS00185 3b1f343d3e2f8de83fa8fa558bb7e674 377 Gene3D G3DSA:3.40.50.2000 2 202 1.8E-78 T 28-03-2018 CWR44_RS00185 3b1f343d3e2f8de83fa8fa558bb7e674 377 SUPERFAMILY SSF53756 1 375 3.77E-134 T 28-03-2018 CWR44_RS00185 3b1f343d3e2f8de83fa8fa558bb7e674 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 364 3.8E-154 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CWR44_RS00185 3b1f343d3e2f8de83fa8fa558bb7e674 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 362 1.9E-116 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CWR44_RS00185 3b1f343d3e2f8de83fa8fa558bb7e674 377 Gene3D G3DSA:3.40.50.2000 203 348 2.8E-29 T 28-03-2018 CWR44_RS10720 909dc6bd199770ce031d1814277eafa3 366 PIRSF PIRSF037489 1 366 9.5E-126 T 28-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CWR44_RS10720 909dc6bd199770ce031d1814277eafa3 366 SUPERFAMILY SSF102705 1 365 1.19E-112 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWR44_RS10720 909dc6bd199770ce031d1814277eafa3 366 Gene3D G3DSA:3.40.1390.30 1 123 2.8E-36 T 28-03-2018 CWR44_RS10720 909dc6bd199770ce031d1814277eafa3 366 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 361 6.0E-66 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWR44_RS10720 909dc6bd199770ce031d1814277eafa3 366 Gene3D G3DSA:3.40.1390.30 241 345 1.1E-8 T 28-03-2018 CWR44_RS10720 909dc6bd199770ce031d1814277eafa3 366 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 344 1.1E-77 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CWR44_RS10720 909dc6bd199770ce031d1814277eafa3 366 Gene3D G3DSA:3.30.70.120 128 233 2.6E-30 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 SUPERFAMILY SSF63520 179 273 7.59E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 ProSitePatterns PS00654 PRD domain signature. 101 113 - T 28-03-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 SUPERFAMILY SSF63520 59 168 4.58E-28 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 Gene3D G3DSA:1.10.1790.10 56 170 1.2E-23 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 SUPERFAMILY SSF50151 4 57 9.94E-15 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 Pfam PF00874 PRD domain 185 273 2.6E-18 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 Pfam PF00874 PRD domain 77 165 1.2E-21 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 Pfam PF03123 CAT RNA binding domain 4 60 2.5E-21 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 Gene3D G3DSA:1.10.1790.10 175 279 4.5E-20 T 28-03-2018 IPR011608 PRD domain GO:0006355 CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 SMART SM01061 4 62 1.4E-25 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR44_RS09810 b9f1fd633bfe1a35f410f3af451f1973 284 Gene3D G3DSA:2.30.24.10 1 55 1.7E-22 T 28-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CWR44_RS08600 89652645d5876352834a77eb1313dcde 91 Pfam PF00886 Ribosomal protein S16 9 68 2.2E-24 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08600 89652645d5876352834a77eb1313dcde 91 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 3.0E-33 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08600 89652645d5876352834a77eb1313dcde 91 Gene3D G3DSA:3.30.1320.10 2 86 1.1E-32 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08600 89652645d5876352834a77eb1313dcde 91 SUPERFAMILY SSF54565 2 85 1.11E-31 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08600 89652645d5876352834a77eb1313dcde 91 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 78 24.319 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 373 383 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 2.0E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 368 380 2.0E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 2.0E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 2.0E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 2.0E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 338 344 2.0E-30 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 Gene3D G3DSA:3.30.9.10 98 205 1.1E-10 T 28-03-2018 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 Gene3D G3DSA:3.30.9.10 206 345 3.0E-41 T 28-03-2018 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 405 531 4.3E-22 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 SUPERFAMILY SSF51905 13 239 3.4E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 Gene3D G3DSA:3.50.50.60 4 95 2.5E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 SUPERFAMILY SSF54373 249 344 1.31E-12 T 28-03-2018 CWR44_RS08915 282670544d6fec2e2f76ba715b81e28e 557 Pfam PF01266 FAD dependent oxidoreductase 21 352 6.8E-60 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CWR44_RS09935 931f65dc34c86d860599f39c98ab2f1c 306 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 33 303 8.4E-87 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CWR44_RS09935 931f65dc34c86d860599f39c98ab2f1c 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 302 1.4E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS09935 931f65dc34c86d860599f39c98ab2f1c 306 Gene3D G3DSA:1.10.3720.10 32 306 6.0E-43 T 28-03-2018 CWR44_RS09935 931f65dc34c86d860599f39c98ab2f1c 306 SUPERFAMILY SSF161098 30 298 4.45E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03780 0ddb8731837e94dcf7e4cd38eb6d4e9e 212 Gene3D G3DSA:3.40.50.720 1 210 4.0E-21 T 28-03-2018 CWR44_RS03780 0ddb8731837e94dcf7e4cd38eb6d4e9e 212 Pfam PF13460 NAD(P)H-binding 7 194 1.6E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS03780 0ddb8731837e94dcf7e4cd38eb6d4e9e 212 SUPERFAMILY SSF51735 1 210 5.86E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 Gene3D G3DSA:3.30.230.10 258 454 3.2E-36 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 SUPERFAMILY SSF54211 299 452 1.02E-39 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 SUPERFAMILY SSF54211 251 265 1.02E-39 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 Hamap MF_01498 DNA repair protein RadA [radA]. 21 452 43.699 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 448 5.2E-199 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 SMART SM00382 87 240 1.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 Gene3D G3DSA:3.40.50.300 53 257 3.3E-24 T 28-03-2018 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 PRINTS PR01874 DNA repair protein radA signature 10 34 2.0E-93 T 28-03-2018 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 PRINTS PR01874 DNA repair protein radA signature 79 107 2.0E-93 T 28-03-2018 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 PRINTS PR01874 DNA repair protein radA signature 170 194 2.0E-93 T 28-03-2018 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 PRINTS PR01874 DNA repair protein radA signature 318 341 2.0E-93 T 28-03-2018 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 PRINTS PR01874 DNA repair protein radA signature 209 237 2.0E-93 T 28-03-2018 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 PRINTS PR01874 DNA repair protein radA signature 244 270 2.0E-93 T 28-03-2018 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 PRINTS PR01874 DNA repair protein radA signature 120 137 2.0E-93 T 28-03-2018 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 Pfam PF13541 Subunit ChlI of Mg-chelatase 353 426 2.3E-6 T 28-03-2018 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 Pfam PF13481 AAA domain 70 218 1.4E-14 T 28-03-2018 CWR44_RS05545 73e87db7ca8e5e96f51248147a3ad0db 454 SUPERFAMILY SSF52540 67 290 9.01E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11705 ee3c2ee251e6601c79b876ced48be1fc 390 ProSitePatterns PS01007 Transposases, Mutator family, signature. 233 257 - T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS11705 ee3c2ee251e6601c79b876ced48be1fc 390 Pfam PF00872 Transposase, Mutator family 1 380 8.9E-167 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CWR44_RS11705 ee3c2ee251e6601c79b876ced48be1fc 390 Gene3D G3DSA:3.30.420.10 159 377 0.0022 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 Pfam PF08442 ATP-grasp domain 2 202 9.0E-84 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 Pfam PF00549 CoA-ligase 262 380 2.0E-24 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 SUPERFAMILY SSF52210 239 386 6.41E-54 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 PIRSF PIRSF001554 1 388 2.4E-158 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 3.2E-167 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 Gene3D G3DSA:3.30.1490.20 21 95 7.3E-25 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 SUPERFAMILY SSF56059 1 238 7.95E-84 T 28-03-2018 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 Gene3D G3DSA:3.30.470.20 96 239 1.8E-58 T 28-03-2018 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 44.837 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CWR44_RS08640 c1b4ed3d1f545f609351ffef0d331fd5 388 Gene3D G3DSA:3.40.50.261 240 385 4.5E-43 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CWR44_RS11290 13f298bf53364fe3610590a7e505f6db 461 Pfam PF07261 Replication initiation and membrane attachment 325 384 7.5E-10 T 28-03-2018 IPR006343 DnaD domain CWR44_RS11290 13f298bf53364fe3610590a7e505f6db 461 Gene3D G3DSA:1.10.10.630 309 383 2.9E-10 T 28-03-2018 IPR034829 DnaD-like domain CWR44_RS12345 04c35e7ab285a8c3451dcda1ef299bea 436 Pfam PF08353 Domain of unknown function (DUF1727) 313 421 3.0E-28 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 CWR44_RS12345 04c35e7ab285a8c3451dcda1ef299bea 436 SUPERFAMILY SSF53623 50 185 6.02E-31 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS12345 04c35e7ab285a8c3451dcda1ef299bea 436 SUPERFAMILY SSF53623 225 292 6.02E-31 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS12345 04c35e7ab285a8c3451dcda1ef299bea 436 Gene3D G3DSA:3.40.1190.10 46 299 1.4E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS12345 04c35e7ab285a8c3451dcda1ef299bea 436 Pfam PF08245 Mur ligase middle domain 53 274 1.6E-17 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS00865 a90cfb775e3c35f8ae1d9a4d19e413b4 145 Gene3D G3DSA:1.10.10.10 2 145 2.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00865 a90cfb775e3c35f8ae1d9a4d19e413b4 145 Pfam PF12802 MarR family 29 87 1.5E-7 T 28-03-2018 CWR44_RS00865 a90cfb775e3c35f8ae1d9a4d19e413b4 145 SUPERFAMILY SSF46785 4 140 2.38E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00865 a90cfb775e3c35f8ae1d9a4d19e413b4 145 SMART SM00347 23 123 5.5E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 SUPERFAMILY SSF55957 359 448 1.19E-25 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 SUPERFAMILY SSF53738 259 367 6.28E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 135 8.8E-42 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 SUPERFAMILY SSF53738 159 258 1.26E-26 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 375 443 1.6E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 444 1.6E-179 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 371 1.1E-32 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 Gene3D G3DSA:3.40.120.10 265 375 9.1E-33 T 28-03-2018 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 Gene3D G3DSA:3.40.120.10 1 149 3.0E-43 T 28-03-2018 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 Gene3D G3DSA:3.30.310.50 376 448 1.4E-23 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 160 255 2.0E-14 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 446 44.915 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 4.1E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 4.1E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 175 194 4.1E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 Gene3D G3DSA:3.40.120.10 158 264 1.7E-25 T 28-03-2018 CWR44_RS00400 77938f3d045d076f22ae372a0d7a11c1 450 SUPERFAMILY SSF53738 3 181 1.96E-46 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CWR44_RS03180 22f1c3ff17fafc474fb853faeb65e484 319 Gene3D G3DSA:1.10.3720.10 1 295 1.4E-19 T 28-03-2018 CWR44_RS03180 22f1c3ff17fafc474fb853faeb65e484 319 SUPERFAMILY SSF161098 93 292 2.8E-8 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03180 22f1c3ff17fafc474fb853faeb65e484 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 306 9.6E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 SUPERFAMILY SSF103473 6 197 4.84E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 SUPERFAMILY SSF103473 248 472 4.84E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 Gene3D G3DSA:1.20.1250.20 4 203 6.3E-35 T 28-03-2018 CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 Pfam PF07690 Major Facilitator Superfamily 19 409 4.4E-54 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 433 3.3E-104 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 1.1E-11 T 28-03-2018 CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 302 326 1.1E-11 T 28-03-2018 CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 1.1E-11 T 28-03-2018 CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 77 99 1.1E-11 T 28-03-2018 CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 1.1E-11 T 28-03-2018 CWR44_RS00470 4a4cc93e02be86956320626d2dd04fb7 483 Gene3D G3DSA:1.20.1250.20 259 483 5.7E-29 T 28-03-2018 CWR44_RS10985 cb4f576d15ef62bc3ab8d8c5aa63173e 86 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 82 2.1E-33 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CWR44_RS10985 cb4f576d15ef62bc3ab8d8c5aa63173e 86 PIRSF PIRSF037258 1 86 5.8E-41 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CWR44_RS10985 cb4f576d15ef62bc3ab8d8c5aa63173e 86 Hamap MF_01507 UPF0297 protein . 1 84 25.098 T 28-03-2018 IPR009309 Uncharacterised protein family UPF0297 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 Pfam PF00226 DnaJ domain 5 66 1.8E-27 T 28-03-2018 IPR001623 DnaJ domain CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 SUPERFAMILY SSF46565 2 103 1.57E-37 T 28-03-2018 IPR001623 DnaJ domain CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 PRINTS PR00625 DnaJ domain signature 61 80 4.2E-32 T 28-03-2018 IPR001623 DnaJ domain CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 PRINTS PR00625 DnaJ domain signature 41 61 4.2E-32 T 28-03-2018 IPR001623 DnaJ domain CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 PRINTS PR00625 DnaJ domain signature 7 25 4.2E-32 T 28-03-2018 IPR001623 DnaJ domain CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 PRINTS PR00625 DnaJ domain signature 25 40 4.2E-32 T 28-03-2018 IPR001623 DnaJ domain CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 SUPERFAMILY SSF49493 263 348 4.19E-23 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 SUPERFAMILY SSF57938 134 214 2.75E-19 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 SUPERFAMILY SSF49493 114 138 1.02E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 SUPERFAMILY SSF49493 218 260 1.02E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 Gene3D G3DSA:2.60.260.20 259 370 9.0E-28 T 28-03-2018 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 Gene3D G3DSA:2.60.260.20 176 258 3.2E-17 T 28-03-2018 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 Pfam PF00684 DnaJ central domain 147 211 4.9E-14 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 SMART SM00271 4 61 6.5E-33 T 28-03-2018 IPR001623 DnaJ domain CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 353 1.4E-140 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 28-03-2018 IPR018253 DnaJ domain, conserved site CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 Gene3D G3DSA:2.60.260.20 115 175 7.1E-11 T 28-03-2018 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 Gene3D G3DSA:1.10.287.110 1 114 8.2E-39 T 28-03-2018 IPR001623 DnaJ domain CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 373 40.665 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CWR44_RS10820 6a4a150b749f3721ad1300e1d0f4053f 377 Pfam PF01556 DnaJ C terminal domain 120 337 3.2E-43 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CWR44_RS05740 2ac827a3d0af537fb19bac1b22968762 139 SUPERFAMILY SSF55729 6 126 4.96E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS05740 2ac827a3d0af537fb19bac1b22968762 139 Gene3D G3DSA:3.40.630.30 7 126 7.8E-15 T 28-03-2018 CWR44_RS05740 2ac827a3d0af537fb19bac1b22968762 139 Pfam PF00583 Acetyltransferase (GNAT) family 23 118 7.9E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS03690 d81c04c709233d38a9c2168edcfa839a 498 Pfam PF00005 ABC transporter 17 167 9.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS03690 d81c04c709233d38a9c2168edcfa839a 498 Pfam PF00005 ABC transporter 268 419 4.3E-14 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS03690 d81c04c709233d38a9c2168edcfa839a 498 SUPERFAMILY SSF52540 2 228 1.28E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03690 d81c04c709233d38a9c2168edcfa839a 498 Gene3D G3DSA:3.40.50.300 1 238 2.7E-53 T 28-03-2018 CWR44_RS03690 d81c04c709233d38a9c2168edcfa839a 498 ProSitePatterns PS00211 ABC transporters family signature. 392 406 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS03690 d81c04c709233d38a9c2168edcfa839a 498 SUPERFAMILY SSF52540 259 480 3.63E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03690 d81c04c709233d38a9c2168edcfa839a 498 SMART SM00382 26 215 4.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03690 d81c04c709233d38a9c2168edcfa839a 498 SMART SM00382 276 468 0.0051 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03690 d81c04c709233d38a9c2168edcfa839a 498 Gene3D G3DSA:3.40.50.300 252 489 9.4E-29 T 28-03-2018 CWR44_RS10260 8738904f18ed817435f144bcdd8b26ca 376 Gene3D G3DSA:3.40.50.2000 186 354 1.1E-39 T 28-03-2018 CWR44_RS10260 8738904f18ed817435f144bcdd8b26ca 376 SUPERFAMILY SSF53756 6 373 4.32E-77 T 28-03-2018 CWR44_RS10260 8738904f18ed817435f144bcdd8b26ca 376 Pfam PF13439 Glycosyltransferase Family 4 11 174 4.3E-19 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CWR44_RS10260 8738904f18ed817435f144bcdd8b26ca 376 Pfam PF00534 Glycosyl transferases group 1 184 344 7.1E-39 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWR44_RS10260 8738904f18ed817435f144bcdd8b26ca 376 Gene3D G3DSA:3.40.50.2000 1 185 3.9E-13 T 28-03-2018 CWR44_RS10260 8738904f18ed817435f144bcdd8b26ca 376 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 1 371 4.1E-164 T 28-03-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 CWR44_RS11970 757d44ba034ba9c5263c75577e718138 369 SUPERFAMILY SSF55781 6 170 4.14E-17 T 28-03-2018 IPR029016 GAF domain-like CWR44_RS11970 757d44ba034ba9c5263c75577e718138 369 Pfam PF13185 GAF domain 25 163 7.0E-13 T 28-03-2018 IPR003018 GAF domain GO:0005515 CWR44_RS11970 757d44ba034ba9c5263c75577e718138 369 Gene3D G3DSA:3.30.450.40 4 180 3.3E-17 T 28-03-2018 IPR029016 GAF domain-like CWR44_RS11970 757d44ba034ba9c5263c75577e718138 369 SUPERFAMILY SSF55874 245 369 1.7E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS11970 757d44ba034ba9c5263c75577e718138 369 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 279 369 1.1E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS11970 757d44ba034ba9c5263c75577e718138 369 Pfam PF07730 Histidine kinase 180 244 7.3E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CWR44_RS11970 757d44ba034ba9c5263c75577e718138 369 Gene3D G3DSA:3.30.565.10 181 369 1.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS03290 df4340bc90cc21037184f8d1f9e7487b 321 SMART SM00876 229 319 8.6E-35 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR44_RS03290 df4340bc90cc21037184f8d1f9e7487b 321 Gene3D G3DSA:3.20.20.70 12 321 6.2E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS03290 df4340bc90cc21037184f8d1f9e7487b 321 Hamap MF_01694 Biotin synthase [bioB]. 13 320 39.258 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR44_RS03290 df4340bc90cc21037184f8d1f9e7487b 321 PIRSF PIRSF001619 1 321 2.3E-120 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR44_RS03290 df4340bc90cc21037184f8d1f9e7487b 321 SUPERFAMILY SSF102114 15 318 3.14E-70 T 28-03-2018 CWR44_RS03290 df4340bc90cc21037184f8d1f9e7487b 321 Pfam PF04055 Radical SAM superfamily 62 217 6.0E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS03290 df4340bc90cc21037184f8d1f9e7487b 321 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 229 318 2.2E-16 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR44_RS03290 df4340bc90cc21037184f8d1f9e7487b 321 TIGRFAM TIGR00433 bioB: biotin synthase 29 318 5.3E-113 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CWR44_RS03290 df4340bc90cc21037184f8d1f9e7487b 321 SMART SM00729 53 261 1.7E-35 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR44_RS02905 bfd8892b9a4299ccf910c98c2514c994 203 Pfam PF00149 Calcineurin-like phosphoesterase 4 150 1.5E-16 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR44_RS02905 bfd8892b9a4299ccf910c98c2514c994 203 SUPERFAMILY SSF56300 3 172 1.83E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS02905 bfd8892b9a4299ccf910c98c2514c994 203 Gene3D G3DSA:3.60.21.10 1 203 4.8E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS03305 c62c9378d0a85418dc17524cfc932ef0 113 Gene3D G3DSA:2.40.50.100 4 112 8.6E-20 T 28-03-2018 CWR44_RS03305 c62c9378d0a85418dc17524cfc932ef0 113 SUPERFAMILY SSF51230 5 111 1.27E-21 T 28-03-2018 IPR011053 Single hybrid motif CWR44_RS03305 c62c9378d0a85418dc17524cfc932ef0 113 Pfam PF01597 Glycine cleavage H-protein 14 107 1.2E-14 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CWR44_RS01330 b1ac2c993e63be417f89efa97e6ceb93 383 Gene3D G3DSA:3.40.50.2000 5 199 0.001 T 28-03-2018 CWR44_RS01330 b1ac2c993e63be417f89efa97e6ceb93 383 Gene3D G3DSA:3.40.50.2000 200 368 4.8E-30 T 28-03-2018 CWR44_RS01330 b1ac2c993e63be417f89efa97e6ceb93 383 Pfam PF00534 Glycosyl transferases group 1 203 360 4.1E-33 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWR44_RS01330 b1ac2c993e63be417f89efa97e6ceb93 383 SUPERFAMILY SSF53756 6 382 5.18E-51 T 28-03-2018 CWR44_RS01665 1b01cdcd2532d1bcf32e549b418f4ed6 466 Pfam PF00324 Amino acid permease 13 447 4.3E-100 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CWR44_RS01665 1b01cdcd2532d1bcf32e549b418f4ed6 466 PIRSF PIRSF006060 1 462 2.3E-65 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS11295 9257943c4cdfb3858595e5c2da81cf45 156 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 78.359 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CWR44_RS11295 9257943c4cdfb3858595e5c2da81cf45 156 Pfam PF03477 ATP cone domain 50 136 4.2E-17 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CWR44_RS11295 9257943c4cdfb3858595e5c2da81cf45 156 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 8.1E-57 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CWR44_RS10610 3c639e6869f245f97eb8352ea7822aad 172 PRINTS PR01100 Shikimate kinase family signature 79 88 9.4E-20 T 28-03-2018 CWR44_RS10610 3c639e6869f245f97eb8352ea7822aad 172 PRINTS PR01100 Shikimate kinase family signature 62 70 9.4E-20 T 28-03-2018 CWR44_RS10610 3c639e6869f245f97eb8352ea7822aad 172 PRINTS PR01100 Shikimate kinase family signature 10 25 9.4E-20 T 28-03-2018 CWR44_RS10610 3c639e6869f245f97eb8352ea7822aad 172 PRINTS PR01100 Shikimate kinase family signature 34 47 9.4E-20 T 28-03-2018 CWR44_RS10610 3c639e6869f245f97eb8352ea7822aad 172 PRINTS PR01100 Shikimate kinase family signature 100 117 9.4E-20 T 28-03-2018 CWR44_RS10610 3c639e6869f245f97eb8352ea7822aad 172 Gene3D G3DSA:3.40.50.300 4 171 5.6E-21 T 28-03-2018 CWR44_RS10610 3c639e6869f245f97eb8352ea7822aad 172 Pfam PF01202 Shikimate kinase 16 169 5.3E-40 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CWR44_RS10610 3c639e6869f245f97eb8352ea7822aad 172 SUPERFAMILY SSF52540 10 166 1.41E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10610 3c639e6869f245f97eb8352ea7822aad 172 ProSitePatterns PS01128 Shikimate kinase signature. 63 87 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CWR44_RS10610 3c639e6869f245f97eb8352ea7822aad 172 Hamap MF_00109 Shikimate kinase [aroK]. 7 170 24.146 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CWR44_RS04910 7b15ceba5ac3197625c8a29041a51f87 422 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 325 345 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWR44_RS04910 7b15ceba5ac3197625c8a29041a51f87 422 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 2 407 3.3E-127 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWR44_RS04910 7b15ceba5ac3197625c8a29041a51f87 422 TIGRFAM TIGR03173 pbuX: xanthine permease 6 410 4.2E-157 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CWR44_RS04910 7b15ceba5ac3197625c8a29041a51f87 422 Pfam PF00860 Permease family 2 378 6.3E-110 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR44_RS01495 bdab47b3c0bd40de208a3c479e04a6d8 227 SUPERFAMILY SSF103501 1 223 1.2E-71 T 28-03-2018 IPR023234 NarG-like domain CWR44_RS01495 bdab47b3c0bd40de208a3c479e04a6d8 227 Gene3D G3DSA:1.20.950.20 1 215 1.8E-45 T 28-03-2018 CWR44_RS01495 bdab47b3c0bd40de208a3c479e04a6d8 227 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 223 8.3E-72 T 28-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 CWR44_RS01495 bdab47b3c0bd40de208a3c479e04a6d8 227 Pfam PF02665 Nitrate reductase gamma subunit 3 222 2.0E-87 T 28-03-2018 IPR023234 NarG-like domain CWR44_RS03000 b821ed4b874105265fc78c4f5d8ad3f4 520 TIGRFAM TIGR03712 acc_sec_asp2: accessory Sec system protein Asp2 6 514 4.7E-241 T 28-03-2018 IPR022267 Accessory Sec system protein Asp2 GO:0015031 CWR44_RS03000 b821ed4b874105265fc78c4f5d8ad3f4 520 SUPERFAMILY SSF53474 281 409 3.08E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS03000 b821ed4b874105265fc78c4f5d8ad3f4 520 Pfam PF16929 Accessory Sec system GspB-transporter 5 513 7.5E-199 T 28-03-2018 IPR022267 Accessory Sec system protein Asp2 GO:0015031 CWR44_RS03000 b821ed4b874105265fc78c4f5d8ad3f4 520 Gene3D G3DSA:3.40.50.1820 284 505 2.1E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS10695 cef77d78b743d5b708253d7cd9d1a44b 140 Gene3D G3DSA:1.10.10.10 6 91 5.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10695 cef77d78b743d5b708253d7cd9d1a44b 140 Pfam PF01475 Ferric uptake regulator family 13 128 3.4E-32 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CWR44_RS10695 cef77d78b743d5b708253d7cd9d1a44b 140 SUPERFAMILY SSF46785 5 132 3.27E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04635 f051c21db703f0a5ccd329918bcfaa63 356 Pfam PF07553 Host cell surface-exposed lipoprotein 210 257 2.5E-13 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 CWR44_RS04635 f051c21db703f0a5ccd329918bcfaa63 356 Pfam PF07553 Host cell surface-exposed lipoprotein 260 305 6.8E-10 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 CWR44_RS04635 f051c21db703f0a5ccd329918bcfaa63 356 Pfam PF07553 Host cell surface-exposed lipoprotein 308 355 1.0E-16 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 CWR44_RS04635 f051c21db703f0a5ccd329918bcfaa63 356 Pfam PF07553 Host cell surface-exposed lipoprotein 110 155 2.9E-17 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 CWR44_RS04635 f051c21db703f0a5ccd329918bcfaa63 356 Pfam PF07553 Host cell surface-exposed lipoprotein 159 206 5.9E-11 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 CWR44_RS12905 e9cddb9de114b019bf14eb0b40c9ecb3 213 Gene3D G3DSA:1.10.3210.10 4 213 1.6E-18 T 28-03-2018 CWR44_RS12905 e9cddb9de114b019bf14eb0b40c9ecb3 213 SMART SM00471 22 137 1.8E-6 T 28-03-2018 IPR003607 HD/PDEase domain CWR44_RS12905 e9cddb9de114b019bf14eb0b40c9ecb3 213 SUPERFAMILY SSF109604 1 212 1.8E-64 T 28-03-2018 CWR44_RS00075 e9cddb9de114b019bf14eb0b40c9ecb3 213 Gene3D G3DSA:1.10.3210.10 4 213 1.6E-18 T 28-03-2018 CWR44_RS00075 e9cddb9de114b019bf14eb0b40c9ecb3 213 SMART SM00471 22 137 1.8E-6 T 28-03-2018 IPR003607 HD/PDEase domain CWR44_RS00075 e9cddb9de114b019bf14eb0b40c9ecb3 213 SUPERFAMILY SSF109604 1 212 1.8E-64 T 28-03-2018 CWR44_RS04700 e11d5bed569d8f10b5b1368a810a3734 116 SUPERFAMILY SSF46785 3 110 2.3E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04700 e11d5bed569d8f10b5b1368a810a3734 116 Gene3D G3DSA:1.10.10.10 18 116 8.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04700 e11d5bed569d8f10b5b1368a810a3734 116 Pfam PF01638 HxlR-like helix-turn-helix 20 109 2.2E-30 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CWR44_RS11625 8b2c0aad0465990ca209be381c8f524f 469 Gene3D G3DSA:3.30.70.360 285 373 1.9E-26 T 28-03-2018 CWR44_RS11625 8b2c0aad0465990ca209be381c8f524f 469 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 12 462 2.1E-183 T 28-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CWR44_RS11625 8b2c0aad0465990ca209be381c8f524f 469 SUPERFAMILY SSF53187 3 183 2.86E-61 T 28-03-2018 CWR44_RS11625 8b2c0aad0465990ca209be381c8f524f 469 SUPERFAMILY SSF53187 384 466 2.86E-61 T 28-03-2018 CWR44_RS11625 8b2c0aad0465990ca209be381c8f524f 469 Gene3D G3DSA:3.30.70.360 204 284 1.0E-8 T 28-03-2018 CWR44_RS11625 8b2c0aad0465990ca209be381c8f524f 469 Pfam PF01546 Peptidase family M20/M25/M40 83 463 5.7E-27 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS11625 8b2c0aad0465990ca209be381c8f524f 469 SUPERFAMILY SSF55031 183 379 1.77E-53 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS11625 8b2c0aad0465990ca209be381c8f524f 469 Gene3D G3DSA:3.40.630.10 2 188 7.4E-26 T 28-03-2018 CWR44_RS01825 28e042eb7494c543fc0d5237699a99bd 153 Pfam PF06998 Protein of unknown function (DUF1307) 27 145 8.2E-23 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 CWR44_RS01825 28e042eb7494c543fc0d5237699a99bd 153 SUPERFAMILY SSF160704 22 147 1.19E-33 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 CWR44_RS01825 28e042eb7494c543fc0d5237699a99bd 153 Gene3D G3DSA:3.30.1830.10 26 147 1.6E-25 T 28-03-2018 CWR44_RS01825 28e042eb7494c543fc0d5237699a99bd 153 PIRSF PIRSF006187 1 149 1.6E-31 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 SMART SM01390 3 91 4.0E-43 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 Gene3D G3DSA:1.10.1050.10 149 200 8.4E-19 T 28-03-2018 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 1.3E-26 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 SUPERFAMILY SSF55174 2 200 3.27E-66 T 28-03-2018 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 34.891 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 Gene3D G3DSA:3.10.290.10 98 148 9.6E-21 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 SMART SM00363 92 156 3.2E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 Pfam PF01479 S4 domain 93 139 1.4E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 Gene3D G3DSA:1.10.1050.10 1 97 1.9E-37 T 28-03-2018 CWR44_RS11465 a493977d004a8dba7e4f39de6a9fc7f5 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 2.5E-81 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWR44_RS03790 b4290f91b9744e2ee78751edb4a380e2 338 SMART SM00116 283 330 0.025 T 28-03-2018 IPR000644 CBS domain CWR44_RS03790 b4290f91b9744e2ee78751edb4a380e2 338 SMART SM00116 226 273 38.0 T 28-03-2018 IPR000644 CBS domain CWR44_RS03790 b4290f91b9744e2ee78751edb4a380e2 338 SUPERFAMILY SSF54631 206 337 6.01E-24 T 28-03-2018 CWR44_RS03790 b4290f91b9744e2ee78751edb4a380e2 338 Pfam PF01595 Domain of unknown function DUF21 9 202 2.5E-49 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CWR44_RS03790 b4290f91b9744e2ee78751edb4a380e2 338 Gene3D G3DSA:3.10.580.10 196 338 7.8E-27 T 28-03-2018 CWR44_RS03790 b4290f91b9744e2ee78751edb4a380e2 338 Pfam PF00571 CBS domain 283 330 9.1E-6 T 28-03-2018 IPR000644 CBS domain CWR44_RS08460 56cd33ba10490333895b8567b1dd34bc 70 SUPERFAMILY SSF63562 1 67 7.15E-18 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWR44_RS08460 56cd33ba10490333895b8567b1dd34bc 70 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 63 13.647 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS08460 56cd33ba10490333895b8567b1dd34bc 70 SMART SM01409 8 62 8.0E-12 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWR44_RS08460 56cd33ba10490333895b8567b1dd34bc 70 Gene3D G3DSA:3.90.940.10 1 69 7.5E-16 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWR44_RS08460 56cd33ba10490333895b8567b1dd34bc 70 Pfam PF01192 RNA polymerase Rpb6 9 61 2.5E-13 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CWR44_RS08460 56cd33ba10490333895b8567b1dd34bc 70 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 3.9E-13 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS10980 16d0d609e66b7e8f8a3a6d5d28f181b9 142 SUPERFAMILY SSF53098 5 141 1.0E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS10980 16d0d609e66b7e8f8a3a6d5d28f181b9 142 Gene3D G3DSA:3.30.420.140 2 142 8.8E-41 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CWR44_RS10980 16d0d609e66b7e8f8a3a6d5d28f181b9 142 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 142 25.488 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CWR44_RS10980 16d0d609e66b7e8f8a3a6d5d28f181b9 142 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 139 9.2E-42 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CWR44_RS10980 16d0d609e66b7e8f8a3a6d5d28f181b9 142 Pfam PF03652 Holliday junction resolvase 5 140 3.0E-41 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CWR44_RS10980 16d0d609e66b7e8f8a3a6d5d28f181b9 142 SMART SM00732 4 107 3.9E-30 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 Gene3D G3DSA:3.40.50.880 1 192 1.8E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 SUPERFAMILY SSF52317 1 189 5.43E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 3.7E-13 T 28-03-2018 CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 3.7E-13 T 28-03-2018 CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 3.7E-13 T 28-03-2018 CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 Pfam PF00117 Glutamine amidotransferase class-I 4 187 2.5E-43 T 28-03-2018 IPR017926 Glutamine amidotransferase CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 100 108 3.4E-30 T 28-03-2018 CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 2 16 3.4E-30 T 28-03-2018 CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 48 57 3.4E-30 T 28-03-2018 CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 120 132 3.4E-30 T 28-03-2018 CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 75 86 3.4E-30 T 28-03-2018 CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 165 178 3.4E-30 T 28-03-2018 CWR44_RS06580 705c4857d80f099abdb87714bacaf32e 197 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 9.6E-54 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 Gene3D G3DSA:3.40.50.880 1 192 1.8E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 SUPERFAMILY SSF52317 1 189 5.43E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 3.7E-13 T 28-03-2018 CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 3.7E-13 T 28-03-2018 CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 3.7E-13 T 28-03-2018 CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 Pfam PF00117 Glutamine amidotransferase class-I 4 187 2.5E-43 T 28-03-2018 IPR017926 Glutamine amidotransferase CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 100 108 3.4E-30 T 28-03-2018 CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 2 16 3.4E-30 T 28-03-2018 CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 48 57 3.4E-30 T 28-03-2018 CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 120 132 3.4E-30 T 28-03-2018 CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 75 86 3.4E-30 T 28-03-2018 CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 PRINTS PR00097 Anthranilate synthase component II signature 165 178 3.4E-30 T 28-03-2018 CWR44_RS12985 705c4857d80f099abdb87714bacaf32e 197 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 9.6E-54 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CWR44_RS10520 309bafe8894d1798bfdef6518b6abf94 561 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 510 1.6E-18 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CWR44_RS10520 309bafe8894d1798bfdef6518b6abf94 561 Gene3D G3DSA:3.40.50.300 209 536 2.4E-17 T 28-03-2018 CWR44_RS10520 309bafe8894d1798bfdef6518b6abf94 561 SUPERFAMILY SSF52540 1 219 2.86E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10520 309bafe8894d1798bfdef6518b6abf94 561 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 553 3.8E-163 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CWR44_RS10520 309bafe8894d1798bfdef6518b6abf94 561 Gene3D G3DSA:3.40.50.300 1 208 7.8E-27 T 28-03-2018 CWR44_RS10520 309bafe8894d1798bfdef6518b6abf94 561 SUPERFAMILY SSF52540 311 507 2.84E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10520 309bafe8894d1798bfdef6518b6abf94 561 SUPERFAMILY SSF52540 3 50 2.84E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10520 309bafe8894d1798bfdef6518b6abf94 561 PIRSF PIRSF003128 1 558 1.0E-173 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CWR44_RS11960 2b25bfc81257e6f11f19c15d408e36b4 154 Pfam PF01381 Helix-turn-helix 15 61 3.2E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS11960 2b25bfc81257e6f11f19c15d408e36b4 154 Gene3D G3DSA:1.10.260.40 9 151 2.7E-10 T 28-03-2018 CWR44_RS11960 2b25bfc81257e6f11f19c15d408e36b4 154 SMART SM00530 13 67 9.5E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS11960 2b25bfc81257e6f11f19c15d408e36b4 154 SUPERFAMILY SSF47413 10 62 8.58E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS00705 cc3b303e20ebd33d50b6397f5895a60f 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 8.5E-28 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00705 cc3b303e20ebd33d50b6397f5895a60f 59 SUPERFAMILY SSF55129 1 58 3.79E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CWR44_RS00705 cc3b303e20ebd33d50b6397f5895a60f 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.853 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00705 cc3b303e20ebd33d50b6397f5895a60f 59 Gene3D G3DSA:3.30.1390.20 4 58 4.9E-25 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CWR44_RS00705 cc3b303e20ebd33d50b6397f5895a60f 59 Pfam PF00327 Ribosomal protein L30p/L7e 5 53 7.4E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CWR44_RS00705 cc3b303e20ebd33d50b6397f5895a60f 59 PIRSF PIRSF002211 1 59 4.0E-28 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS01865 3b8f478e2601623cf40b111f1e34f27e 88 Pfam PF07205 Domain of unknown function (DUF1413) 11 72 5.3E-7 T 28-03-2018 IPR010813 Protein of unknown function DUF1413 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 PRINTS PR00125 ATP synthase delta subunit signature 150 168 8.6E-23 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 PRINTS PR00125 ATP synthase delta subunit signature 4 23 8.6E-23 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 PRINTS PR00125 ATP synthase delta subunit signature 84 98 8.6E-23 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 PRINTS PR00125 ATP synthase delta subunit signature 73 84 8.6E-23 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 PRINTS PR00125 ATP synthase delta subunit signature 135 150 8.6E-23 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 4 174 7.8E-37 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 SUPERFAMILY SSF47928 2 104 4.32E-23 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 4 174 3.5E-42 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 1 177 16.767 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 Gene3D G3DSA:1.10.520.20 1 105 2.7E-20 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00160 e3f15a0c2cb5effaf36a6841da5fdbf1 179 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS13125 6dcebd44588bd62132fd3d992e928b44 299 Pfam PF01636 Phosphotransferase enzyme family 27 262 3.9E-23 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CWR44_RS13125 6dcebd44588bd62132fd3d992e928b44 299 SUPERFAMILY SSF56112 4 263 8.78E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CWR44_RS13125 6dcebd44588bd62132fd3d992e928b44 299 Gene3D G3DSA:3.90.1200.10 117 281 2.7E-15 T 28-03-2018 CWR44_RS05880 7c7cd6be1c33b7a0fc69b5cf473ebf69 468 SUPERFAMILY SSF103473 17 434 4.71E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS05880 7c7cd6be1c33b7a0fc69b5cf473ebf69 468 Gene3D G3DSA:1.20.1250.20 15 226 1.8E-23 T 28-03-2018 CWR44_RS05880 7c7cd6be1c33b7a0fc69b5cf473ebf69 468 Pfam PF07690 Major Facilitator Superfamily 65 358 3.3E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS05880 7c7cd6be1c33b7a0fc69b5cf473ebf69 468 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CWR44_RS05880 7c7cd6be1c33b7a0fc69b5cf473ebf69 468 Gene3D G3DSA:1.20.1250.20 243 440 1.5E-25 T 28-03-2018 CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 SUPERFAMILY SSF52540 176 377 3.98E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 Gene3D G3DSA:1.20.120.140 74 174 3.0E-22 T 28-03-2018 CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 105 378 8.6E-118 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 ProSitePatterns PS00018 EF-hand calcium-binding domain. 56 68 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 352 365 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 104 379 63.694 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 SUPERFAMILY SSF47364 78 155 3.66E-19 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 SMART SM00382 177 357 7.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 SMART SM00963 80 161 1.3E-22 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 SMART SM00962 178 379 5.4E-124 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 Pfam PF02881 SRP54-type protein, helical bundle domain 92 156 1.3E-12 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 Gene3D G3DSA:3.40.50.300 175 380 8.4E-42 T 28-03-2018 CWR44_RS08585 643ca1f9d93e2c1b0e9954c841b99517 407 Pfam PF00448 SRP54-type protein, GTPase domain 179 378 2.5E-81 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 Pfam PF01168 Alanine racemase, N-terminal domain 13 229 5.6E-63 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 Pfam PF00842 Alanine racemase, C-terminal domain 246 368 3.5E-40 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 SUPERFAMILY SSF51419 13 238 5.52E-59 T 28-03-2018 IPR029066 PLP-binding barrel CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 SUPERFAMILY SSF50621 239 377 3.92E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 PRINTS PR00992 Alanine racemase signature 351 364 1.9E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 PRINTS PR00992 Alanine racemase signature 67 85 1.9E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 PRINTS PR00992 Alanine racemase signature 260 275 1.9E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 PRINTS PR00992 Alanine racemase signature 31 47 1.9E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 PRINTS PR00992 Alanine racemase signature 164 175 1.9E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 PRINTS PR00992 Alanine racemase signature 129 141 1.9E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 PRINTS PR00992 Alanine racemase signature 202 229 1.9E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 PRINTS PR00992 Alanine racemase signature 277 292 1.9E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 PRINTS PR00992 Alanine racemase signature 297 314 1.9E-58 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 Hamap MF_01201 Alanine racemase. 6 369 32.102 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 TIGRFAM TIGR00492 alr: alanine racemase 8 368 1.6E-105 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 SMART SM01005 244 369 4.0E-61 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 Gene3D G3DSA:3.20.20.10 6 226 1.1E-43 T 28-03-2018 IPR029066 PLP-binding barrel CWR44_RS12835 1ad4d8aeb763fabf5a51ec0019421471 382 Gene3D G3DSA:2.40.37.10 227 378 1.1E-51 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR44_RS10835 21197cd7081a548985fd2b17a43150d7 325 Gene3D G3DSA:3.30.450.40 182 324 2.5E-24 T 28-03-2018 IPR029016 GAF domain-like CWR44_RS10835 21197cd7081a548985fd2b17a43150d7 325 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 325 4.2E-87 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CWR44_RS10835 21197cd7081a548985fd2b17a43150d7 325 PIRSF PIRSF005485 1 325 1.0E-85 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CWR44_RS10835 21197cd7081a548985fd2b17a43150d7 325 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 325 26.098 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CWR44_RS10835 21197cd7081a548985fd2b17a43150d7 325 Pfam PF01628 HrcA protein C terminal domain 107 318 2.8E-36 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CWR44_RS10835 21197cd7081a548985fd2b17a43150d7 325 Gene3D G3DSA:1.10.10.10 1 87 8.1E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10835 21197cd7081a548985fd2b17a43150d7 325 SUPERFAMILY SSF55781 71 324 1.49E-46 T 28-03-2018 IPR029016 GAF domain-like CWR44_RS10835 21197cd7081a548985fd2b17a43150d7 325 SUPERFAMILY SSF46785 1 82 8.68E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04105 c7e30c7546715b26eb4fefa170f4d017 312 Pfam PF00294 pfkB family carbohydrate kinase 15 302 3.1E-49 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CWR44_RS04105 c7e30c7546715b26eb4fefa170f4d017 312 PRINTS PR00990 Ribokinase signature 19 40 3.1E-9 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR44_RS04105 c7e30c7546715b26eb4fefa170f4d017 312 PRINTS PR00990 Ribokinase signature 190 205 3.1E-9 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR44_RS04105 c7e30c7546715b26eb4fefa170f4d017 312 PRINTS PR00990 Ribokinase signature 229 240 3.1E-9 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR44_RS04105 c7e30c7546715b26eb4fefa170f4d017 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 258 271 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR44_RS04105 c7e30c7546715b26eb4fefa170f4d017 312 Gene3D G3DSA:3.40.1190.20 13 309 7.4E-49 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS04105 c7e30c7546715b26eb4fefa170f4d017 312 SUPERFAMILY SSF53613 14 304 7.17E-56 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS10905 3618dea33ee4ee8b2c0c7a3190c6ef31 366 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 365 1.2E-149 T 28-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH CWR44_RS10905 3618dea33ee4ee8b2c0c7a3190c6ef31 366 Gene3D G3DSA:3.40.50.300 56 224 3.9E-34 T 28-03-2018 CWR44_RS10905 3618dea33ee4ee8b2c0c7a3190c6ef31 366 SUPERFAMILY SSF52540 67 280 5.97E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10905 3618dea33ee4ee8b2c0c7a3190c6ef31 366 Pfam PF01926 50S ribosome-binding GTPase 162 231 3.8E-14 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS12370 238ccd68fc1dbf6a6b88f3716605d540 454 SUPERFAMILY SSF53335 69 452 3.17E-86 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS12370 238ccd68fc1dbf6a6b88f3716605d540 454 Gene3D G3DSA:3.40.50.150 170 451 1.8E-51 T 28-03-2018 CWR44_RS12370 238ccd68fc1dbf6a6b88f3716605d540 454 Gene3D G3DSA:3.40.50.150 76 137 9.1E-13 T 28-03-2018 CWR44_RS12370 238ccd68fc1dbf6a6b88f3716605d540 454 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 384 415 - T 28-03-2018 IPR030390 RNA methyltransferase TrmA, active site CWR44_RS12370 238ccd68fc1dbf6a6b88f3716605d540 454 SUPERFAMILY SSF50249 11 66 9.14E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS12370 238ccd68fc1dbf6a6b88f3716605d540 454 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 90 453 1.7E-24 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CWR44_RS12370 238ccd68fc1dbf6a6b88f3716605d540 454 Gene3D G3DSA:2.40.50.140 2 75 3.8E-24 T 28-03-2018 CWR44_RS12370 238ccd68fc1dbf6a6b88f3716605d540 454 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 445 7.9E-153 T 28-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CWR44_RS12370 238ccd68fc1dbf6a6b88f3716605d540 454 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 435 445 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CWR44_RS10220 9de282d6c17b2448f191ac3cc0f691dd 759 SUPERFAMILY SSF53955 70 279 1.27E-69 T 28-03-2018 IPR023346 Lysozyme-like domain CWR44_RS10220 9de282d6c17b2448f191ac3cc0f691dd 759 SUPERFAMILY SSF56601 298 670 2.92E-81 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR44_RS10220 9de282d6c17b2448f191ac3cc0f691dd 759 Pfam PF00912 Transglycosylase 80 255 4.2E-62 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWR44_RS10220 9de282d6c17b2448f191ac3cc0f691dd 759 Gene3D G3DSA:3.40.710.10 284 733 2.7E-68 T 28-03-2018 CWR44_RS10220 9de282d6c17b2448f191ac3cc0f691dd 759 Gene3D G3DSA:1.10.3810.10 72 272 4.5E-74 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWR44_RS10220 9de282d6c17b2448f191ac3cc0f691dd 759 Pfam PF00905 Penicillin binding protein transpeptidase domain 361 622 2.6E-25 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR44_RS08555 22399eab8aa5ed0dda5b9711266200ac 328 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 328 142.687 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CWR44_RS08555 22399eab8aa5ed0dda5b9711266200ac 328 Gene3D G3DSA:3.40.718.10 1 327 1.2E-103 T 28-03-2018 CWR44_RS08555 22399eab8aa5ed0dda5b9711266200ac 328 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 2 320 4.5E-120 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CWR44_RS08555 22399eab8aa5ed0dda5b9711266200ac 328 Pfam PF02504 Fatty acid synthesis protein 2 313 2.0E-111 T 28-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CWR44_RS08555 22399eab8aa5ed0dda5b9711266200ac 328 PIRSF PIRSF002465 1 327 4.4E-126 T 28-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CWR44_RS08555 22399eab8aa5ed0dda5b9711266200ac 328 SUPERFAMILY SSF53659 1 323 2.84E-102 T 28-03-2018 CWR44_RS05330 186268991ffa1367781d5380de8c5cf2 321 SUPERFAMILY SSF53271 76 312 5.46E-65 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWR44_RS05330 186268991ffa1367781d5380de8c5cf2 321 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 12 321 4.2E-126 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWR44_RS05330 186268991ffa1367781d5380de8c5cf2 321 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 135 150 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CWR44_RS05330 186268991ffa1367781d5380de8c5cf2 321 Pfam PF14572 Phosphoribosyl synthetase-associated domain 212 320 2.3E-26 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWR44_RS05330 186268991ffa1367781d5380de8c5cf2 321 Gene3D G3DSA:3.40.50.2020 8 161 2.2E-67 T 28-03-2018 CWR44_RS05330 186268991ffa1367781d5380de8c5cf2 321 SMART SM01400 11 127 2.9E-80 T 28-03-2018 CWR44_RS05330 186268991ffa1367781d5380de8c5cf2 321 Gene3D G3DSA:3.40.50.2020 162 299 3.6E-40 T 28-03-2018 CWR44_RS05330 186268991ffa1367781d5380de8c5cf2 321 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 11 321 49.655 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWR44_RS05330 186268991ffa1367781d5380de8c5cf2 321 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 11 127 1.1E-50 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CWR44_RS12190 737a97344010f9abad919ece853ae2fc 429 Gene3D G3DSA:3.40.640.10 62 307 5.7E-73 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS12190 737a97344010f9abad919ece853ae2fc 429 SUPERFAMILY SSF53383 2 427 7.43E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS12190 737a97344010f9abad919ece853ae2fc 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 90.521 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CWR44_RS12190 737a97344010f9abad919ece853ae2fc 429 Gene3D G3DSA:3.90.1150.10 308 429 5.5E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS12190 737a97344010f9abad919ece853ae2fc 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS12190 737a97344010f9abad919ece853ae2fc 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 9 427 2.4E-167 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CWR44_RS12190 737a97344010f9abad919ece853ae2fc 429 Pfam PF00202 Aminotransferase class-III 35 415 5.6E-73 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS03840 1a85912f7f4e1d315c8d5495fd883520 318 SUPERFAMILY SSF161098 90 289 3.79E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03840 1a85912f7f4e1d315c8d5495fd883520 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 2.5E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03840 1a85912f7f4e1d315c8d5495fd883520 318 Gene3D G3DSA:1.10.3720.10 84 297 5.0E-23 T 28-03-2018 CWR44_RS07465 e1d2e36001b08059664677f060b19fbb 125 Pfam PF13038 Domain of unknown function (DUF3899) 34 123 3.6E-22 T 28-03-2018 IPR025007 Domain of unknown function DUF3899 CWR44_RS05575 800395b158ae807dd9ffd056b9708769 249 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 242 2.4E-81 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CWR44_RS05575 800395b158ae807dd9ffd056b9708769 249 SUPERFAMILY SSF55315 4 76 2.0E-16 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWR44_RS05575 800395b158ae807dd9ffd056b9708769 249 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 6 79 1.5E-20 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWR44_RS05575 800395b158ae807dd9ffd056b9708769 249 Pfam PF00588 SpoU rRNA Methylase family 97 236 1.6E-40 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CWR44_RS05575 800395b158ae807dd9ffd056b9708769 249 SUPERFAMILY SSF75217 67 243 3.92E-50 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR44_RS05575 800395b158ae807dd9ffd056b9708769 249 Gene3D G3DSA:3.30.1330.30 2 75 4.8E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWR44_RS05575 800395b158ae807dd9ffd056b9708769 249 Gene3D G3DSA:3.40.1280.10 80 249 4.3E-48 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR44_RS05575 800395b158ae807dd9ffd056b9708769 249 SMART SM00967 5 79 1.0E-19 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWR44_RS01855 ddbbb43fe70f62db45c8f38855a2e01f 410 Pfam PF01546 Peptidase family M20/M25/M40 70 402 6.5E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS01855 ddbbb43fe70f62db45c8f38855a2e01f 410 Gene3D G3DSA:3.30.70.360 184 310 1.6E-18 T 28-03-2018 CWR44_RS01855 ddbbb43fe70f62db45c8f38855a2e01f 410 Pfam PF07687 Peptidase dimerisation domain 173 294 3.5E-23 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS01855 ddbbb43fe70f62db45c8f38855a2e01f 410 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 8 396 4.4E-99 T 28-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CWR44_RS01855 ddbbb43fe70f62db45c8f38855a2e01f 410 Gene3D G3DSA:3.40.630.10 1 183 1.8E-33 T 28-03-2018 CWR44_RS01855 ddbbb43fe70f62db45c8f38855a2e01f 410 SUPERFAMILY SSF53187 3 169 4.0E-57 T 28-03-2018 CWR44_RS01855 ddbbb43fe70f62db45c8f38855a2e01f 410 SUPERFAMILY SSF53187 322 405 4.0E-57 T 28-03-2018 CWR44_RS01855 ddbbb43fe70f62db45c8f38855a2e01f 410 SUPERFAMILY SSF55031 199 293 1.05E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS01030 a20f78d83ecca76f41d23b5c7554620b 318 SUPERFAMILY SSF51735 100 285 3.41E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS01030 a20f78d83ecca76f41d23b5c7554620b 318 SUPERFAMILY SSF52283 3 133 2.08E-33 T 28-03-2018 CWR44_RS01030 a20f78d83ecca76f41d23b5c7554620b 318 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CWR44_RS01030 a20f78d83ecca76f41d23b5c7554620b 318 Gene3D G3DSA:3.40.50.720 110 287 3.6E-54 T 28-03-2018 CWR44_RS01030 a20f78d83ecca76f41d23b5c7554620b 318 Gene3D G3DSA:3.40.50.720 1 109 2.1E-32 T 28-03-2018 CWR44_RS01030 a20f78d83ecca76f41d23b5c7554620b 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 285 2.0E-60 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWR44_RS01030 a20f78d83ecca76f41d23b5c7554620b 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 317 3.8E-32 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 Gene3D G3DSA:3.50.50.60 156 324 9.1E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 9.4E-13 T 28-03-2018 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.4E-13 T 28-03-2018 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 9.4E-13 T 28-03-2018 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 9.4E-13 T 28-03-2018 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.5E-18 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 1.5E-18 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 211 227 1.5E-18 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 287 305 1.5E-18 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 1.5E-18 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 SUPERFAMILY SSF51905 7 264 6.22E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 291 1.2E-96 T 28-03-2018 CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 320 4.8E-138 T 28-03-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA CWR44_RS10355 6c75eddbf70fe90b18d641075c06fc3c 328 Gene3D G3DSA:3.50.50.60 3 153 1.0E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 TIGRFAM TIGR00016 ackA: acetate kinase 2 395 4.6E-170 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 SUPERFAMILY SSF53067 4 196 9.5E-71 T 28-03-2018 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 PIRSF PIRSF000722 1 398 6.8E-154 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 Pfam PF00871 Acetokinase family 5 390 4.2E-167 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 Gene3D G3DSA:3.30.420.40 196 397 2.7E-82 T 28-03-2018 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 SUPERFAMILY SSF53067 158 394 5.83E-93 T 28-03-2018 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 Hamap MF_00020 Acetate kinase [ackA]. 1 398 196.757 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 PRINTS PR00471 Acetate kinase family signature 203 224 9.5E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 PRINTS PR00471 Acetate kinase family signature 300 313 9.5E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 PRINTS PR00471 Acetate kinase family signature 5 16 9.5E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 PRINTS PR00471 Acetate kinase family signature 173 186 9.5E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 PRINTS PR00471 Acetate kinase family signature 377 389 9.5E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 PRINTS PR00471 Acetate kinase family signature 322 338 9.5E-47 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CWR44_RS11420 72df9a03307abefeb36d8a1e9b46949e 398 Gene3D G3DSA:3.30.420.40 4 195 3.6E-78 T 28-03-2018 CWR44_RS05275 5f4f57a3867df18ffa35c4245b92bf79 280 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 200 2.6E-29 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS05275 5f4f57a3867df18ffa35c4245b92bf79 280 SUPERFAMILY SSF53790 2 221 5.1E-78 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS05275 5f4f57a3867df18ffa35c4245b92bf79 280 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 4 276 5.0E-79 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS05275 5f4f57a3867df18ffa35c4245b92bf79 280 Gene3D G3DSA:3.40.1010.10 1 111 1.9E-42 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS05275 5f4f57a3867df18ffa35c4245b92bf79 280 PIRSF PIRSF005917 1 280 5.0E-99 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS05275 5f4f57a3867df18ffa35c4245b92bf79 280 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 81 92 - T 28-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS05275 5f4f57a3867df18ffa35c4245b92bf79 280 Gene3D G3DSA:3.30.950.10 112 226 3.1E-32 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS05275 5f4f57a3867df18ffa35c4245b92bf79 280 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 3 223 35.706 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS02770 b42bf3fd9b243dc9c6a78046fc09d0d2 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 28.382 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CWR44_RS02770 b42bf3fd9b243dc9c6a78046fc09d0d2 208 Pfam PF02525 Flavodoxin-like fold 3 202 3.2E-44 T 28-03-2018 IPR003680 Flavodoxin-like fold CWR44_RS02770 b42bf3fd9b243dc9c6a78046fc09d0d2 208 Gene3D G3DSA:3.40.50.360 3 208 1.0E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS02770 b42bf3fd9b243dc9c6a78046fc09d0d2 208 SUPERFAMILY SSF52218 3 208 5.16E-50 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS02490 731cec274d1191195b396e575b45f75b 497 Gene3D G3DSA:3.50.50.60 1 387 1.1E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS02490 731cec274d1191195b396e575b45f75b 497 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 6 487 2.2E-190 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS02490 731cec274d1191195b396e575b45f75b 497 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 1 490 51.899 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS02490 731cec274d1191195b396e575b45f75b 497 SUPERFAMILY SSF51905 1 272 4.4E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS02490 731cec274d1191195b396e575b45f75b 497 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 4 490 1.1E-216 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS03755 472d8fd58c0b5eeab98d8bd37c9f7971 469 PIRSF PIRSF006060 1 469 4.5E-65 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS03755 472d8fd58c0b5eeab98d8bd37c9f7971 469 Pfam PF00324 Amino acid permease 13 442 3.0E-105 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 PRINTS PR01036 Tetracycline resistance protein TetB signature 245 267 9.3E-11 T 28-03-2018 CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 PRINTS PR01036 Tetracycline resistance protein TetB signature 306 330 9.3E-11 T 28-03-2018 CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 PRINTS PR01036 Tetracycline resistance protein TetB signature 185 209 9.3E-11 T 28-03-2018 CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 PRINTS PR01036 Tetracycline resistance protein TetB signature 470 494 9.3E-11 T 28-03-2018 CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 SUPERFAMILY SSF103473 176 365 3.79E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 SUPERFAMILY SSF103473 639 672 3.79E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 SUPERFAMILY SSF103473 416 587 3.79E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 Gene3D G3DSA:1.20.1250.20 176 371 4.1E-36 T 28-03-2018 CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 183 662 1.6E-140 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 Pfam PF07690 Major Facilitator Superfamily 187 577 2.9E-56 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS01250 445501c4f3da1686ad241c0d85582c94 684 Gene3D G3DSA:1.20.1250.20 427 679 6.8E-30 T 28-03-2018 CWR44_RS12450 5eea92a9e08b949786124204612489e9 355 Gene3D G3DSA:3.90.340.10 1 118 1.6E-40 T 28-03-2018 CWR44_RS12450 5eea92a9e08b949786124204612489e9 355 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 61 68 - T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CWR44_RS12450 5eea92a9e08b949786124204612489e9 355 Gene3D G3DSA:3.90.1230.10 181 291 1.9E-46 T 28-03-2018 CWR44_RS12450 5eea92a9e08b949786124204612489e9 355 Pfam PF02898 Nitric oxide synthase, oxygenase domain 2 348 1.6E-149 T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CWR44_RS12450 5eea92a9e08b949786124204612489e9 355 PIRSF PIRSF037219 1 354 4.0E-150 T 28-03-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.13.165|KEGG: 00330+1.14.13.165 CWR44_RS12450 5eea92a9e08b949786124204612489e9 355 SUPERFAMILY SSF56512 2 354 2.62E-159 T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 109 9.6E-44 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 Gene3D G3DSA:3.40.50.20 1 122 3.8E-51 T 28-03-2018 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 319 2.4E-63 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 284 291 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 Gene3D G3DSA:3.30.470.20 208 448 5.0E-83 T 28-03-2018 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 SUPERFAMILY SSF56059 82 350 1.54E-68 T 28-03-2018 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 Pfam PF02785 Biotin carboxylase C-terminal domain 334 443 8.9E-35 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 SUPERFAMILY SSF51246 329 445 2.3E-35 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 SUPERFAMILY SSF52440 3 112 4.53E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 SMART SM00878 334 443 2.1E-47 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CWR44_RS10930 52ff1d27e71a1df2b81cecaf425acde1 453 Gene3D G3DSA:3.30.1490.20 123 207 5.9E-24 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR44_RS08005 d4e928cae6524714125cc6bbd85c1441 90 Hamap MF_01041 UPF0223 protein . 1 89 25.726 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CWR44_RS08005 d4e928cae6524714125cc6bbd85c1441 90 Gene3D G3DSA:1.10.220.80 12 87 9.3E-31 T 28-03-2018 IPR023324 BH2638-like domain CWR44_RS08005 d4e928cae6524714125cc6bbd85c1441 90 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 83 4.6E-36 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CWR44_RS08005 d4e928cae6524714125cc6bbd85c1441 90 PIRSF PIRSF037260 1 89 8.5E-40 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CWR44_RS08005 d4e928cae6524714125cc6bbd85c1441 90 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 1 83 9.0E-33 T 28-03-2018 IPR007920 Protein of unknown function UPF0223 CWR44_RS08005 d4e928cae6524714125cc6bbd85c1441 90 SUPERFAMILY SSF158504 4 82 4.58E-34 T 28-03-2018 IPR023324 BH2638-like domain CWR44_RS12665 b3072b406c6d324ff5fc8d4df5c96cd1 494 Gene3D G3DSA:2.60.120.560 357 486 7.4E-28 T 28-03-2018 CWR44_RS12665 b3072b406c6d324ff5fc8d4df5c96cd1 494 Gene3D G3DSA:2.115.10.20 43 356 6.6E-88 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWR44_RS12665 b3072b406c6d324ff5fc8d4df5c96cd1 494 SUPERFAMILY SSF49899 343 492 4.75E-29 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CWR44_RS12665 b3072b406c6d324ff5fc8d4df5c96cd1 494 SMART SM00640 38 456 6.6E-130 T 28-03-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 CWR44_RS12665 b3072b406c6d324ff5fc8d4df5c96cd1 494 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 344 487 2.3E-24 T 28-03-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal CWR44_RS12665 b3072b406c6d324ff5fc8d4df5c96cd1 494 SUPERFAMILY SSF75005 30 340 5.18E-101 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CWR44_RS12665 b3072b406c6d324ff5fc8d4df5c96cd1 494 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 38 51 - T 28-03-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CWR44_RS12665 b3072b406c6d324ff5fc8d4df5c96cd1 494 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 38 340 1.8E-93 T 28-03-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal CWR44_RS12665 b3072b406c6d324ff5fc8d4df5c96cd1 494 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 22 467 2.9E-174 T 28-03-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 CWR44_RS11810 cc71a9535a709e02b127847193adb999 530 Gene3D G3DSA:3.90.228.20 216 294 1.7E-29 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CWR44_RS11810 cc71a9535a709e02b127847193adb999 530 Gene3D G3DSA:3.90.228.20 295 526 2.8E-95 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CWR44_RS11810 cc71a9535a709e02b127847193adb999 530 Gene3D G3DSA:3.40.449.10 22 214 1.1E-76 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CWR44_RS11810 cc71a9535a709e02b127847193adb999 530 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 253 268 - T 28-03-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CWR44_RS11810 cc71a9535a709e02b127847193adb999 530 Pfam PF01293 Phosphoenolpyruvate carboxykinase 23 482 1.8E-221 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CWR44_RS11810 cc71a9535a709e02b127847193adb999 530 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 23 526 8.8E-237 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CWR44_RS11810 cc71a9535a709e02b127847193adb999 530 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 14 530 56.145 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CWR44_RS11810 cc71a9535a709e02b127847193adb999 530 SUPERFAMILY SSF53795 216 517 9.61E-132 T 28-03-2018 CWR44_RS11810 cc71a9535a709e02b127847193adb999 530 PIRSF PIRSF006294 2 528 8.2E-242 T 28-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CWR44_RS11810 cc71a9535a709e02b127847193adb999 530 SUPERFAMILY SSF68923 15 215 3.31E-77 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CWR44_RS06395 f3067c1394f638722240f74112713891 284 SUPERFAMILY SSF53850 88 283 9.9E-21 T 28-03-2018 CWR44_RS06395 f3067c1394f638722240f74112713891 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS06395 f3067c1394f638722240f74112713891 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS06395 f3067c1394f638722240f74112713891 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.2E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS06395 f3067c1394f638722240f74112713891 284 Gene3D G3DSA:1.10.10.10 1 86 2.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06395 f3067c1394f638722240f74112713891 284 Gene3D G3DSA:3.40.190.10 169 251 3.8E-6 T 28-03-2018 CWR44_RS06395 f3067c1394f638722240f74112713891 284 SUPERFAMILY SSF46785 1 110 7.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06395 f3067c1394f638722240f74112713891 284 Pfam PF03466 LysR substrate binding domain 88 279 7.2E-23 T 28-03-2018 IPR005119 LysR, substrate-binding CWR44_RS06395 f3067c1394f638722240f74112713891 284 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.1E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS06395 f3067c1394f638722240f74112713891 284 Gene3D G3DSA:3.40.190.10 87 168 4.1E-9 T 28-03-2018 CWR44_RS02365 428db21f10db8fc51d3fa55c01d98dfb 284 Pfam PF03881 Fructosamine kinase 12 283 9.9E-74 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CWR44_RS02365 428db21f10db8fc51d3fa55c01d98dfb 284 Gene3D G3DSA:3.30.200.20 2 85 2.9E-16 T 28-03-2018 CWR44_RS02365 428db21f10db8fc51d3fa55c01d98dfb 284 PIRSF PIRSF006221 1 284 5.9E-89 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CWR44_RS02365 428db21f10db8fc51d3fa55c01d98dfb 284 Gene3D G3DSA:3.90.1200.10 86 283 2.7E-17 T 28-03-2018 CWR44_RS02365 428db21f10db8fc51d3fa55c01d98dfb 284 SUPERFAMILY SSF56112 9 279 2.62E-46 T 28-03-2018 IPR011009 Protein kinase-like domain CWR44_RS10365 5bd0f1b306e53236d2563c8f7a5b888f 459 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 129 138 - T 28-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site CWR44_RS10365 5bd0f1b306e53236d2563c8f7a5b888f 459 Pfam PF16124 RecQ zinc-binding 394 427 5.8E-6 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CWR44_RS10365 5bd0f1b306e53236d2563c8f7a5b888f 459 SUPERFAMILY SSF52540 22 334 4.77E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10365 5bd0f1b306e53236d2563c8f7a5b888f 459 SMART SM00487 11 203 6.7E-33 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS10365 5bd0f1b306e53236d2563c8f7a5b888f 459 Gene3D G3DSA:3.40.50.300 197 432 7.2E-43 T 28-03-2018 CWR44_RS10365 5bd0f1b306e53236d2563c8f7a5b888f 459 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 342 7.3E-95 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CWR44_RS10365 5bd0f1b306e53236d2563c8f7a5b888f 459 Pfam PF00271 Helicase conserved C-terminal domain 212 318 1.5E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS10365 5bd0f1b306e53236d2563c8f7a5b888f 459 SMART SM00490 238 319 1.6E-23 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS10365 5bd0f1b306e53236d2563c8f7a5b888f 459 Gene3D G3DSA:3.40.50.300 1 194 1.0E-34 T 28-03-2018 CWR44_RS10365 5bd0f1b306e53236d2563c8f7a5b888f 459 Pfam PF00270 DEAD/DEAH box helicase 17 175 2.7E-21 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR44_RS10300 8aaaa6cecf5feb7688fe0d12fed1eca7 388 TIGRFAM TIGR00033 aroC: chorismate synthase 1 368 2.9E-120 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR44_RS10300 8aaaa6cecf5feb7688fe0d12fed1eca7 388 Pfam PF01264 Chorismate synthase 1 362 2.1E-115 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR44_RS10300 8aaaa6cecf5feb7688fe0d12fed1eca7 388 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR44_RS10300 8aaaa6cecf5feb7688fe0d12fed1eca7 388 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR44_RS10300 8aaaa6cecf5feb7688fe0d12fed1eca7 388 SUPERFAMILY SSF103263 1 383 9.81E-137 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR44_RS10300 8aaaa6cecf5feb7688fe0d12fed1eca7 388 Gene3D G3DSA:3.60.150.10 1 387 1.6E-130 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR44_RS10300 8aaaa6cecf5feb7688fe0d12fed1eca7 388 ProSitePatterns PS00789 Chorismate synthase signature 3. 337 353 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR44_RS10300 8aaaa6cecf5feb7688fe0d12fed1eca7 388 Hamap MF_00300 Chorismate synthase [aroC]. 1 370 34.172 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR44_RS10300 8aaaa6cecf5feb7688fe0d12fed1eca7 388 PIRSF PIRSF001456 1 380 5.4E-122 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 Pfam PF00162 Phosphoglycerate kinase 6 384 4.2E-152 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 PRINTS PR00477 Phosphoglycerate kinase family signature 348 359 7.2E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 7.2E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 PRINTS PR00477 Phosphoglycerate kinase family signature 314 339 7.2E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 7.2E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 7.2E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 PRINTS PR00477 Phosphoglycerate kinase family signature 142 164 7.2E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 PRINTS PR00477 Phosphoglycerate kinase family signature 371 388 7.2E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 7.2E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 PRINTS PR00477 Phosphoglycerate kinase family signature 172 194 7.2E-90 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 Gene3D G3DSA:3.40.50.1260 184 383 1.5E-81 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 395 40.472 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 SUPERFAMILY SSF53748 4 395 4.59E-149 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 PIRSF PIRSF000724 1 396 1.5E-140 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06930 6536dc7cf33f5b97d7f0e8e33ced0717 396 Gene3D G3DSA:3.40.50.1260 3 183 2.3E-67 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS08610 7464f0f4876d5f36fb4f0da382ea2dd0 245 Gene3D G3DSA:3.40.1280.10 1 167 7.0E-80 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR44_RS08610 7464f0f4876d5f36fb4f0da382ea2dd0 245 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 232 4.4E-102 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWR44_RS08610 7464f0f4876d5f36fb4f0da382ea2dd0 245 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 219 2.8E-73 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWR44_RS08610 7464f0f4876d5f36fb4f0da382ea2dd0 245 SUPERFAMILY SSF75217 1 242 1.2E-105 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR44_RS08610 7464f0f4876d5f36fb4f0da382ea2dd0 245 PIRSF PIRSF000386 1 245 4.3E-107 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWR44_RS08610 7464f0f4876d5f36fb4f0da382ea2dd0 245 Gene3D G3DSA:1.10.1270.20 168 245 3.0E-35 T 28-03-2018 CWR44_RS08610 7464f0f4876d5f36fb4f0da382ea2dd0 245 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 245 114.005 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CWR44_RS00775 7695aad33df84cdedec5e126938d605e 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.2E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00775 7695aad33df84cdedec5e126938d605e 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.2E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00775 7695aad33df84cdedec5e126938d605e 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.2E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00775 7695aad33df84cdedec5e126938d605e 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.636 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00775 7695aad33df84cdedec5e126938d605e 92 Pfam PF00203 Ribosomal protein S19 3 83 1.7E-37 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00775 7695aad33df84cdedec5e126938d605e 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00775 7695aad33df84cdedec5e126938d605e 92 SUPERFAMILY SSF54570 3 84 7.59E-36 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00775 7695aad33df84cdedec5e126938d605e 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 2.8E-48 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWR44_RS00775 7695aad33df84cdedec5e126938d605e 92 PIRSF PIRSF002144 1 92 5.2E-33 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00775 7695aad33df84cdedec5e126938d605e 92 Gene3D G3DSA:3.30.860.10 1 92 3.0E-41 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS11510 68b76c3603f17f5c05717a91405792a1 469 PRINTS PR01988 Putative bacilysin exporter bacE signature 438 461 9.8E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CWR44_RS11510 68b76c3603f17f5c05717a91405792a1 469 PRINTS PR01988 Putative bacilysin exporter bacE signature 230 251 9.8E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CWR44_RS11510 68b76c3603f17f5c05717a91405792a1 469 PRINTS PR01988 Putative bacilysin exporter bacE signature 140 158 9.8E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CWR44_RS11510 68b76c3603f17f5c05717a91405792a1 469 Pfam PF07690 Major Facilitator Superfamily 21 414 7.8E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS11510 68b76c3603f17f5c05717a91405792a1 469 Gene3D G3DSA:1.20.1250.20 257 468 6.7E-25 T 28-03-2018 CWR44_RS11510 68b76c3603f17f5c05717a91405792a1 469 SUPERFAMILY SSF103473 8 199 6.93E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS11510 68b76c3603f17f5c05717a91405792a1 469 SUPERFAMILY SSF103473 253 462 6.93E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS11510 68b76c3603f17f5c05717a91405792a1 469 Gene3D G3DSA:1.20.1250.20 7 204 8.1E-23 T 28-03-2018 CWR44_RS11510 68b76c3603f17f5c05717a91405792a1 469 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 427 1.0E-79 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CWR44_RS12670 2d1116e05fcfe2a174432db300d7ac30 319 Pfam PF13407 Periplasmic binding protein domain 64 300 2.1E-14 T 28-03-2018 IPR025997 Periplasmic binding protein CWR44_RS12670 2d1116e05fcfe2a174432db300d7ac30 319 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CWR44_RS12670 2d1116e05fcfe2a174432db300d7ac30 319 SUPERFAMILY SSF47413 2 59 6.75E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS12670 2d1116e05fcfe2a174432db300d7ac30 319 SUPERFAMILY SSF53822 58 316 1.14E-56 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWR44_RS12670 2d1116e05fcfe2a174432db300d7ac30 319 Gene3D G3DSA:3.40.50.2300 54 171 3.5E-29 T 28-03-2018 CWR44_RS12670 2d1116e05fcfe2a174432db300d7ac30 319 SMART SM00354 1 70 5.3E-31 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS12670 2d1116e05fcfe2a174432db300d7ac30 319 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 47 7.9E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS12670 2d1116e05fcfe2a174432db300d7ac30 319 Gene3D G3DSA:1.10.260.40 3 53 1.8E-18 T 28-03-2018 CWR44_RS12670 2d1116e05fcfe2a174432db300d7ac30 319 Gene3D G3DSA:3.40.50.2300 172 306 8.3E-18 T 28-03-2018 CWR44_RS05260 73115cb1421621b430faa54a8f3923f6 132 PIRSF PIRSF021439 1 132 1.0E-26 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CWR44_RS05260 73115cb1421621b430faa54a8f3923f6 132 Gene3D G3DSA:1.20.5.400 2 81 3.5E-4 T 28-03-2018 CWR44_RS05260 73115cb1421621b430faa54a8f3923f6 132 Pfam PF06156 Initiation control protein YabA 2 127 8.8E-25 T 28-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CWR44_RS12760 b2dd28a1e4489b942eda1f498419e2ab 422 Gene3D G3DSA:3.40.50.1100 55 106 5.3E-22 T 28-03-2018 CWR44_RS12760 b2dd28a1e4489b942eda1f498419e2ab 422 TIGRFAM TIGR02079 THD1: threonine dehydratase 10 422 1.4E-184 T 28-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CWR44_RS12760 b2dd28a1e4489b942eda1f498419e2ab 422 SUPERFAMILY SSF53686 10 366 1.02E-96 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR44_RS12760 b2dd28a1e4489b942eda1f498419e2ab 422 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 47 60 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CWR44_RS12760 b2dd28a1e4489b942eda1f498419e2ab 422 Gene3D G3DSA:3.40.50.1100 107 341 1.7E-50 T 28-03-2018 CWR44_RS12760 b2dd28a1e4489b942eda1f498419e2ab 422 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 329 421 1.3E-20 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CWR44_RS12760 b2dd28a1e4489b942eda1f498419e2ab 422 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 316 3.5E-72 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR44_RS00700 121f45cbe716d11424dba436c0d23d03 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 4.0E-37 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CWR44_RS00700 121f45cbe716d11424dba436c0d23d03 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 142 6.3E-54 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00700 121f45cbe716d11424dba436c0d23d03 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.144 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CWR44_RS00700 121f45cbe716d11424dba436c0d23d03 146 SUPERFAMILY SSF52080 4 142 6.93E-48 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CWR44_RS00700 121f45cbe716d11424dba436c0d23d03 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00700 121f45cbe716d11424dba436c0d23d03 146 Gene3D G3DSA:3.100.10.10 42 146 1.8E-31 T 28-03-2018 CWR44_RS04565 c57f4230f96f369b9eb8b5745c5d6c7b 247 Pfam PF04199 Putative cyclase 19 185 1.1E-33 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CWR44_RS04565 c57f4230f96f369b9eb8b5745c5d6c7b 247 Gene3D G3DSA:3.50.30.50 14 247 9.3E-51 T 28-03-2018 CWR44_RS04565 c57f4230f96f369b9eb8b5745c5d6c7b 247 SUPERFAMILY SSF102198 16 246 2.49E-54 T 28-03-2018 CWR44_RS01920 4c1563dd91df469dbad41c694c5454b6 232 SMART SM00954 77 200 1.7E-41 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR44_RS01920 4c1563dd91df469dbad41c694c5454b6 232 SUPERFAMILY SSF81301 40 231 3.11E-53 T 28-03-2018 CWR44_RS01920 4c1563dd91df469dbad41c694c5454b6 232 Pfam PF04607 Region found in RelA / SpoT proteins 77 197 2.6E-37 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR44_RS01920 4c1563dd91df469dbad41c694c5454b6 232 Gene3D G3DSA:3.30.460.10 37 181 1.5E-36 T 28-03-2018 CWR44_RS01920 4c1563dd91df469dbad41c694c5454b6 232 Gene3D G3DSA:1.10.287.860 183 230 8.2E-15 T 28-03-2018 CWR44_RS01915 8a6403a2458f371325c215b118320c68 291 SUPERFAMILY SSF53474 28 290 2.13E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS01915 8a6403a2458f371325c215b118320c68 291 Pfam PF12146 Serine aminopeptidase, S33 33 264 7.7E-11 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CWR44_RS01915 8a6403a2458f371325c215b118320c68 291 Gene3D G3DSA:3.40.50.1820 17 288 3.3E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 SUPERFAMILY SSF52343 255 375 3.14E-23 T 28-03-2018 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 Gene3D G3DSA:1.10.490.10 1 156 3.1E-32 T 28-03-2018 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 SUPERFAMILY SSF63380 146 252 6.63E-19 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 PRINTS PR00409 Phthalate dioxygenase reductase family signature 261 280 5.7E-9 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 PRINTS PR00409 Phthalate dioxygenase reductase family signature 200 214 5.7E-9 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 PRINTS PR00409 Phthalate dioxygenase reductase family signature 341 349 5.7E-9 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 PRINTS PR00409 Phthalate dioxygenase reductase family signature 239 253 5.7E-9 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 Pfam PF00175 Oxidoreductase NAD-binding domain 262 354 4.0E-6 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 Pfam PF00970 Oxidoreductase FAD-binding domain 152 251 4.7E-9 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 Pfam PF00042 Globin 7 102 8.9E-9 T 28-03-2018 IPR000971 Globin GO:0020037 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 SUPERFAMILY SSF46458 1 149 2.49E-37 T 28-03-2018 IPR009050 Globin-like CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 Gene3D G3DSA:3.40.50.80 253 381 9.8E-20 T 28-03-2018 CWR44_RS07805 b62b7a2d245a4cc046e1eac84fc2e090 381 Gene3D G3DSA:2.40.30.10 157 252 1.7E-19 T 28-03-2018 CWR44_RS08830 9790ebd3144400624296fca0ddc3478e 380 PIRSF PIRSF006728 1 380 7.6E-112 T 28-03-2018 IPR008135 Competence-induced protein CinA CWR44_RS08830 9790ebd3144400624296fca0ddc3478e 380 SUPERFAMILY SSF53218 1 203 8.9E-37 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS08830 9790ebd3144400624296fca0ddc3478e 380 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 380 104.051 T 28-03-2018 IPR008135 Competence-induced protein CinA CWR44_RS08830 9790ebd3144400624296fca0ddc3478e 380 SMART SM00852 4 171 1.0E-34 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS08830 9790ebd3144400624296fca0ddc3478e 380 Gene3D G3DSA:3.40.980.10 1 172 2.3E-43 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS08830 9790ebd3144400624296fca0ddc3478e 380 Pfam PF00994 Probable molybdopterin binding domain 5 168 4.1E-32 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS08830 9790ebd3144400624296fca0ddc3478e 380 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 166 5.4E-30 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS08830 9790ebd3144400624296fca0ddc3478e 380 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 2 283 1.1E-90 T 28-03-2018 IPR008135 Competence-induced protein CinA CWR44_RS06095 bf65daab0135171043cd381668da128e 168 Gene3D G3DSA:3.30.1450.10 36 109 0.0097 T 28-03-2018 CWR44_RS05340 f6610a11c6ee3b7a3ec3f0f45dc23d19 190 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 186 8.2E-64 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWR44_RS05340 f6610a11c6ee3b7a3ec3f0f45dc23d19 190 SUPERFAMILY SSF53178 1 186 1.31E-67 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWR44_RS05340 f6610a11c6ee3b7a3ec3f0f45dc23d19 190 Pfam PF01195 Peptidyl-tRNA hydrolase 4 186 7.0E-57 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWR44_RS05340 f6610a11c6ee3b7a3ec3f0f45dc23d19 190 Gene3D G3DSA:3.40.50.1470 1 190 3.2E-71 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWR44_RS05340 f6610a11c6ee3b7a3ec3f0f45dc23d19 190 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CWR44_RS05340 f6610a11c6ee3b7a3ec3f0f45dc23d19 190 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CWR44_RS05340 f6610a11c6ee3b7a3ec3f0f45dc23d19 190 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 36.907 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CWR44_RS07345 8af64bb87019d2283f308b2617e6dc96 539 Pfam PF01609 Transposase DDE domain 264 515 8.5E-38 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS07345 8af64bb87019d2283f308b2617e6dc96 539 Gene3D G3DSA:3.90.350.10 257 498 1.7E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS07345 8af64bb87019d2283f308b2617e6dc96 539 Pfam PF05598 Transposase domain (DUF772) 49 117 1.5E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS13150 8af64bb87019d2283f308b2617e6dc96 539 Pfam PF01609 Transposase DDE domain 264 515 8.5E-38 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS13150 8af64bb87019d2283f308b2617e6dc96 539 Gene3D G3DSA:3.90.350.10 257 498 1.7E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS13150 8af64bb87019d2283f308b2617e6dc96 539 Pfam PF05598 Transposase domain (DUF772) 49 117 1.5E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS00570 2de6d845c63cdf17e0c402d96052da6c 336 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 149 170 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CWR44_RS00570 2de6d845c63cdf17e0c402d96052da6c 336 Pfam PF00107 Zinc-binding dehydrogenase 160 249 2.4E-15 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR44_RS00570 2de6d845c63cdf17e0c402d96052da6c 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 87 4.4E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWR44_RS00570 2de6d845c63cdf17e0c402d96052da6c 336 SMART SM00829 11 333 1.7E-9 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR44_RS00570 2de6d845c63cdf17e0c402d96052da6c 336 Gene3D G3DSA:3.90.180.10 6 160 4.3E-39 T 28-03-2018 CWR44_RS00570 2de6d845c63cdf17e0c402d96052da6c 336 Gene3D G3DSA:3.40.50.720 161 267 8.5E-14 T 28-03-2018 CWR44_RS00570 2de6d845c63cdf17e0c402d96052da6c 336 SUPERFAMILY SSF51735 115 283 5.82E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS00570 2de6d845c63cdf17e0c402d96052da6c 336 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 334 9.7E-100 T 28-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 CWR44_RS00570 2de6d845c63cdf17e0c402d96052da6c 336 SUPERFAMILY SSF50129 15 140 3.35E-31 T 28-03-2018 IPR011032 GroES-like CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 SUPERFAMILY SSF52374 5 316 1.31E-111 T 28-03-2018 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 Gene3D G3DSA:1.10.1160.10 247 333 3.0E-31 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 Gene3D G3DSA:3.40.50.620 130 246 1.6E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 323 6.9E-124 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 Gene3D G3DSA:3.40.50.620 5 129 6.3E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 SUPERFAMILY SSF48163 298 483 2.35E-48 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 8.5E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 8.5E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 8.5E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 8.5E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 8.5E-27 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 Gene3D G3DSA:1.10.8.70 335 381 1.9E-4 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 484 33.839 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 483 3.0E-187 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWR44_RS05555 a10d1f15ce25a6aa0ab6c10cad3371e6 484 Gene3D G3DSA:1.10.10.350 386 484 2.0E-28 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 Pfam PF04998 RNA polymerase Rpb1, domain 5 774 1134 9.2E-69 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1185 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 Gene3D G3DSA:2.40.40.20 335 477 6.9E-39 T 28-03-2018 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1195 18.555 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 667 4.3E-34 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 Gene3D G3DSA:2.40.50.100 914 1033 1.0E-38 T 28-03-2018 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 SUPERFAMILY SSF64484 5 1184 0.0 T 28-03-2018 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 2.3E-88 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 SMART SM00663 224 503 1.2E-181 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 Pfam PF05000 RNA polymerase Rpb1, domain 4 696 763 1.3E-14 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS05640 a68158ffdbc3c2b644b11a988ec8d5af 1206 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 474 2.1E-38 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS09560 2545ec06f6003ca42da1b0a916e6ec79 134 Gene3D G3DSA:2.30.30.290 57 134 1.2E-15 T 28-03-2018 IPR023385 YopX-like domain, beta barrel type CWR44_RS09560 2545ec06f6003ca42da1b0a916e6ec79 134 TIGRFAM TIGR01671 phage_TIGR01671: phage conserved hypothetical protein TIGR01671 2 128 7.6E-19 T 28-03-2018 IPR010024 Conserved hypothetical protein CHP1671 CWR44_RS09560 2545ec06f6003ca42da1b0a916e6ec79 134 Gene3D G3DSA:3.30.1490.160 1 56 8.5E-13 T 28-03-2018 CWR44_RS09560 2545ec06f6003ca42da1b0a916e6ec79 134 Pfam PF09643 YopX protein 3 128 5.2E-25 T 28-03-2018 IPR019096 YopX protein CWR44_RS09560 2545ec06f6003ca42da1b0a916e6ec79 134 SUPERFAMILY SSF159006 1 128 8.24E-28 T 28-03-2018 CWR44_RS05950 d12ed77fe6829c0b25f74d48d39b7a4c 358 TIGRFAM TIGR01220 Pmev_kin_Gr_pos: phosphomevalonate kinase 2 358 4.5E-198 T 28-03-2018 IPR005917 Phosphomevalonate kinase KEGG: 00900+2.7.4.2|MetaCyc: PWY-7391|MetaCyc: PWY-922 CWR44_RS05950 d12ed77fe6829c0b25f74d48d39b7a4c 358 SUPERFAMILY SSF55060 214 354 1.39E-33 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS05950 d12ed77fe6829c0b25f74d48d39b7a4c 358 Pfam PF08544 GHMP kinases C terminal 261 347 1.1E-10 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS05950 d12ed77fe6829c0b25f74d48d39b7a4c 358 SUPERFAMILY SSF54211 1 230 6.53E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS05950 d12ed77fe6829c0b25f74d48d39b7a4c 358 PRINTS PR00959 Mevalonate kinase family signature 313 330 1.0E-6 T 28-03-2018 CWR44_RS05950 d12ed77fe6829c0b25f74d48d39b7a4c 358 PRINTS PR00959 Mevalonate kinase family signature 6 30 1.0E-6 T 28-03-2018 CWR44_RS05950 d12ed77fe6829c0b25f74d48d39b7a4c 358 PRINTS PR00959 Mevalonate kinase family signature 112 134 1.0E-6 T 28-03-2018 CWR44_RS05950 d12ed77fe6829c0b25f74d48d39b7a4c 358 Gene3D G3DSA:3.30.70.890 221 358 5.2E-26 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS05950 d12ed77fe6829c0b25f74d48d39b7a4c 358 Gene3D G3DSA:3.30.230.10 1 220 6.1E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS05950 d12ed77fe6829c0b25f74d48d39b7a4c 358 Pfam PF00288 GHMP kinases N terminal domain 103 174 6.5E-14 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWR44_RS00640 cf4f180daec78fc9d57fcec97624471e 267 Pfam PF01416 tRNA pseudouridine synthase 142 240 1.0E-28 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS00640 cf4f180daec78fc9d57fcec97624471e 267 Pfam PF01416 tRNA pseudouridine synthase 8 103 1.4E-9 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS00640 cf4f180daec78fc9d57fcec97624471e 267 SUPERFAMILY SSF55120 2 245 2.01E-80 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS00640 cf4f180daec78fc9d57fcec97624471e 267 PIRSF PIRSF001430 1 259 5.3E-78 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS00640 cf4f180daec78fc9d57fcec97624471e 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 243 34.062 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS00640 cf4f180daec78fc9d57fcec97624471e 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 238 2.0E-67 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS00640 cf4f180daec78fc9d57fcec97624471e 267 Gene3D G3DSA:3.30.70.580 1 104 1.5E-29 T 28-03-2018 CWR44_RS00640 cf4f180daec78fc9d57fcec97624471e 267 Gene3D G3DSA:3.30.70.660 105 242 3.1E-37 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS11040 cbfae7ea387872672616de207554663a 258 SUPERFAMILY SSF69572 4 246 4.71E-58 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CWR44_RS11040 cbfae7ea387872672616de207554663a 258 Pfam PF00899 ThiF family 7 170 6.0E-34 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CWR44_RS11040 cbfae7ea387872672616de207554663a 258 Gene3D G3DSA:3.40.50.720 1 251 7.4E-42 T 28-03-2018 CWR44_RS06815 df1dc24ea5a4320531545a53524cc561 286 SMART SM00257 59 102 3.3E-4 T 28-03-2018 IPR018392 LysM domain CWR44_RS06815 df1dc24ea5a4320531545a53524cc561 286 SUPERFAMILY SSF54106 59 101 7.19E-8 T 28-03-2018 IPR018392 LysM domain CWR44_RS06815 df1dc24ea5a4320531545a53524cc561 286 Pfam PF05257 CHAP domain 180 263 2.4E-14 T 28-03-2018 IPR007921 CHAP domain CWR44_RS06815 df1dc24ea5a4320531545a53524cc561 286 SUPERFAMILY SSF54001 176 273 3.83E-19 T 28-03-2018 CWR44_RS06815 df1dc24ea5a4320531545a53524cc561 286 Gene3D G3DSA:3.10.350.10 53 106 1.2E-10 T 28-03-2018 CWR44_RS06815 df1dc24ea5a4320531545a53524cc561 286 Pfam PF01476 LysM domain 61 99 1.5E-6 T 28-03-2018 IPR018392 LysM domain CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Gene3D G3DSA:3.40.50.1380 919 1048 1.1E-33 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 1.7E-40 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.5E-64 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 SUPERFAMILY SSF56059 666 926 2.3E-100 T 28-03-2018 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Gene3D G3DSA:3.30.470.20 738 918 1.1E-40 T 28-03-2018 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 SUPERFAMILY SSF52335 935 1051 2.35E-31 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 SMART SM01096 420 540 6.2E-68 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 SUPERFAMILY SSF56059 128 399 1.61E-106 T 28-03-2018 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Gene3D G3DSA:1.10.1030.10 405 531 2.6E-48 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 1.5E-38 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 2.2E-79 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 SUPERFAMILY SSF52440 549 668 5.32E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 SUPERFAMILY SSF48108 395 546 9.29E-52 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 SMART SM00851 949 1035 1.8E-24 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1045 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Gene3D G3DSA:3.30.1490.20 648 737 2.5E-23 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Pfam PF02142 MGS-like domain 949 1035 1.7E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Gene3D G3DSA:3.40.50.20 532 647 2.1E-59 T 28-03-2018 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1057 13.372 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Gene3D G3DSA:3.30.470.20 129 401 2.9E-64 T 28-03-2018 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 SUPERFAMILY SSF52440 1 127 4.17E-48 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1056 13.055 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 Gene3D G3DSA:3.40.50.20 4 128 8.6E-37 T 28-03-2018 CWR44_RS08425 eb95ee367ae33ebc92d145262b76e8e1 1057 SMART SM01209 672 837 3.5E-4 T 28-03-2018 CWR44_RS00490 57823b7e6b60c6f882764e9784c446f7 395 Pfam PF01704 UTP--glucose-1-phosphate uridylyltransferase 51 376 5.0E-39 T 28-03-2018 IPR002618 UDPGP family GO:0008152|GO:0070569 CWR44_RS00490 57823b7e6b60c6f882764e9784c446f7 395 SUPERFAMILY SSF53448 6 393 5.84E-122 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS00490 57823b7e6b60c6f882764e9784c446f7 395 Gene3D G3DSA:3.90.550.10 3 394 9.9E-104 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS10840 bad7727d3634955fa31f3e44a3cbc3d9 373 Gene3D G3DSA:3.20.20.70 5 315 3.3E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS10840 bad7727d3634955fa31f3e44a3cbc3d9 373 Pfam PF06969 HemN C-terminal domain 298 359 1.4E-13 T 28-03-2018 IPR010723 HemN, C-terminal CWR44_RS10840 bad7727d3634955fa31f3e44a3cbc3d9 373 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 355 1.9E-116 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CWR44_RS10840 bad7727d3634955fa31f3e44a3cbc3d9 373 SUPERFAMILY SSF102114 5 371 2.22E-114 T 28-03-2018 CWR44_RS10840 bad7727d3634955fa31f3e44a3cbc3d9 373 Pfam PF04055 Radical SAM superfamily 8 171 1.5E-22 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS10840 bad7727d3634955fa31f3e44a3cbc3d9 373 SMART SM00729 3 217 2.1E-61 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR44_RS07400 4c4ca3f523b9128a1a1bdc3ab4dc6517 1162 Gene3D G3DSA:3.40.50.300 255 685 1.3E-31 T 28-03-2018 CWR44_RS07400 4c4ca3f523b9128a1a1bdc3ab4dc6517 1162 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1159 0.0 T 28-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CWR44_RS07400 4c4ca3f523b9128a1a1bdc3ab4dc6517 1162 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1159 52.016 T 28-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CWR44_RS07400 4c4ca3f523b9128a1a1bdc3ab4dc6517 1162 Gene3D G3DSA:3.40.50.300 117 254 1.0E-25 T 28-03-2018 CWR44_RS07400 4c4ca3f523b9128a1a1bdc3ab4dc6517 1162 Gene3D G3DSA:3.40.50.300 1 116 2.3E-26 T 28-03-2018 CWR44_RS07400 4c4ca3f523b9128a1a1bdc3ab4dc6517 1162 Pfam PF13361 UvrD-like helicase C-terminal domain 284 617 6.7E-12 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWR44_RS07400 4c4ca3f523b9128a1a1bdc3ab4dc6517 1162 Pfam PF12705 PD-(D/E)XK nuclease superfamily 773 1127 9.3E-49 T 28-03-2018 CWR44_RS07400 4c4ca3f523b9128a1a1bdc3ab4dc6517 1162 SUPERFAMILY SSF52540 293 691 2.55E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11835 1f0158e902fa92ec55f92adc5beb3d4b 464 Pfam PF00501 AMP-binding enzyme 6 371 1.6E-64 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CWR44_RS11835 1f0158e902fa92ec55f92adc5beb3d4b 464 Gene3D G3DSA:3.40.50.980 1 141 4.6E-20 T 28-03-2018 CWR44_RS11835 1f0158e902fa92ec55f92adc5beb3d4b 464 SUPERFAMILY SSF56801 5 461 1.96E-103 T 28-03-2018 CWR44_RS11835 1f0158e902fa92ec55f92adc5beb3d4b 464 Gene3D G3DSA:3.40.50.980 142 287 4.8E-32 T 28-03-2018 CWR44_RS11835 1f0158e902fa92ec55f92adc5beb3d4b 464 Pfam PF13193 AMP-binding enzyme C-terminal domain 380 453 3.8E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CWR44_RS11835 1f0158e902fa92ec55f92adc5beb3d4b 464 Gene3D G3DSA:3.30.300.30 365 464 1.0E-23 T 28-03-2018 CWR44_RS11835 1f0158e902fa92ec55f92adc5beb3d4b 464 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 1 462 41.434 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 CWR44_RS11835 1f0158e902fa92ec55f92adc5beb3d4b 464 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 26 458 5.3E-165 T 28-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 CWR44_RS11835 1f0158e902fa92ec55f92adc5beb3d4b 464 Gene3D G3DSA:2.30.38.10 288 364 2.8E-14 T 28-03-2018 CWR44_RS03245 50366f10a0ec3be41117264576dad803 242 Gene3D G3DSA:3.40.50.1360 1 242 8.7E-67 T 28-03-2018 CWR44_RS03245 50366f10a0ec3be41117264576dad803 242 SUPERFAMILY SSF100950 1 237 4.33E-83 T 28-03-2018 CWR44_RS03245 50366f10a0ec3be41117264576dad803 242 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 2 237 2.6E-76 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CWR44_RS03245 50366f10a0ec3be41117264576dad803 242 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 13 227 9.0E-23 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CWR44_RS03245 50366f10a0ec3be41117264576dad803 242 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 242 39.299 T 28-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CWR44_RS04145 f4a3057948997f6ca9daf7e3fa58437d 442 Gene3D G3DSA:3.40.250.10 263 343 1.4E-8 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS04145 f4a3057948997f6ca9daf7e3fa58437d 442 SMART SM00450 350 442 2.9E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS04145 f4a3057948997f6ca9daf7e3fa58437d 442 SUPERFAMILY SSF56281 1 256 1.96E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS04145 f4a3057948997f6ca9daf7e3fa58437d 442 Pfam PF00753 Metallo-beta-lactamase superfamily 13 163 1.5E-6 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS04145 f4a3057948997f6ca9daf7e3fa58437d 442 SUPERFAMILY SSF52821 362 439 7.6E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS04145 f4a3057948997f6ca9daf7e3fa58437d 442 SMART SM00849 12 195 2.1E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS04145 f4a3057948997f6ca9daf7e3fa58437d 442 Gene3D G3DSA:3.60.15.10 1 262 2.3E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS04145 f4a3057948997f6ca9daf7e3fa58437d 442 Gene3D G3DSA:3.40.250.10 344 441 1.5E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS04145 f4a3057948997f6ca9daf7e3fa58437d 442 SUPERFAMILY SSF52821 237 340 2.1E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS04145 f4a3057948997f6ca9daf7e3fa58437d 442 Pfam PF00581 Rhodanese-like domain 362 440 2.2E-11 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS02880 35f449eb7d9dac210a640365187b2b90 938 Pfam PF12698 ABC-2 family transporter protein 30 178 6.5E-11 T 28-03-2018 CWR44_RS02880 35f449eb7d9dac210a640365187b2b90 938 Pfam PF12698 ABC-2 family transporter protein 603 915 2.8E-14 T 28-03-2018 CWR44_RS02880 35f449eb7d9dac210a640365187b2b90 938 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 714 917 3.8E-50 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CWR44_RS02880 35f449eb7d9dac210a640365187b2b90 938 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 172 7.7E-49 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CWR44_RS02880 35f449eb7d9dac210a640365187b2b90 938 Gene3D G3DSA:3.40.1710.10 47 210 4.3E-26 T 28-03-2018 CWR44_RS02880 35f449eb7d9dac210a640365187b2b90 938 Gene3D G3DSA:1.20.1170.10 292 715 3.3E-6 T 28-03-2018 CWR44_RS10655 69b856a1ca7bcc2d27af31576d46d4c8 107 SUPERFAMILY SSF89957 1 103 9.94E-30 T 28-03-2018 IPR029756 MTH1187/YkoF-like CWR44_RS10655 69b856a1ca7bcc2d27af31576d46d4c8 107 Pfam PF01910 Thiamine-binding protein 4 99 1.4E-32 T 28-03-2018 IPR002767 Thiamine-binding protein CWR44_RS10655 69b856a1ca7bcc2d27af31576d46d4c8 107 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 102 7.6E-36 T 28-03-2018 IPR002767 Thiamine-binding protein CWR44_RS10655 69b856a1ca7bcc2d27af31576d46d4c8 107 Gene3D G3DSA:3.30.70.930 1 107 1.7E-32 T 28-03-2018 IPR029756 MTH1187/YkoF-like CWR44_RS07365 bd321c5eda06452b34a3984fadf11dc8 320 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 68 311 4.5E-47 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CWR44_RS07365 bd321c5eda06452b34a3984fadf11dc8 320 Gene3D G3DSA:3.20.20.190 40 320 8.8E-78 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR44_RS07365 bd321c5eda06452b34a3984fadf11dc8 320 SUPERFAMILY SSF51695 64 314 1.18E-68 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR44_RS00230 49a43adab025465e3ee02a0b0e0e2578 85 Pfam PF01197 Ribosomal protein L31 1 79 5.1E-27 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00230 49a43adab025465e3ee02a0b0e0e2578 85 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00230 49a43adab025465e3ee02a0b0e0e2578 85 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 27.714 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00230 49a43adab025465e3ee02a0b0e0e2578 85 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 2.0E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00230 49a43adab025465e3ee02a0b0e0e2578 85 PRINTS PR01249 Ribosomal protein L31 signature 2 19 6.2E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00230 49a43adab025465e3ee02a0b0e0e2578 85 PRINTS PR01249 Ribosomal protein L31 signature 60 78 6.2E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00230 49a43adab025465e3ee02a0b0e0e2578 85 PRINTS PR01249 Ribosomal protein L31 signature 45 60 6.2E-18 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00230 49a43adab025465e3ee02a0b0e0e2578 85 SUPERFAMILY SSF143800 1 80 9.42E-24 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08125 0284b75cc2ee7b9069baddede5cb6d23 83 PIRSF PIRSF031653 1 83 1.2E-26 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CWR44_RS08125 0284b75cc2ee7b9069baddede5cb6d23 83 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 6 75 1.1E-23 T 28-03-2018 IPR016979 Protein of unknown function DUF2129 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 SUPERFAMILY SSF158472 186 235 7.98E-10 T 28-03-2018 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 455 3.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 Gene3D G3DSA:1.10.287.130 229 299 5.7E-14 T 28-03-2018 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 303 1.2E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 SMART SM00304 186 238 8.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 453 1.3E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.3E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.3E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 1.3E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 SUPERFAMILY SSF55874 313 453 6.55E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 Gene3D G3DSA:3.30.565.10 310 456 1.6E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 Pfam PF00672 HAMP domain 187 234 1.0E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 SMART SM00388 239 304 3.5E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 SMART SM00387 348 456 6.5E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01310 2025302c2f19f1407410b73d41029eb2 456 SUPERFAMILY SSF47384 222 303 1.26E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS08785 dc170611e62d1f1be1748f4eb7272f60 557 Gene3D G3DSA:3.60.15.10 3 450 3.5E-53 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS08785 dc170611e62d1f1be1748f4eb7272f60 557 SMART SM00849 23 217 3.9E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS08785 dc170611e62d1f1be1748f4eb7272f60 557 PIRSF PIRSF004803 2 557 3.4E-194 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CWR44_RS08785 dc170611e62d1f1be1748f4eb7272f60 557 SUPERFAMILY SSF56281 11 424 6.09E-73 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS08785 dc170611e62d1f1be1748f4eb7272f60 557 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 363 409 8.4E-10 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CWR44_RS08785 dc170611e62d1f1be1748f4eb7272f60 557 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 11 554 5.2E-179 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CWR44_RS08785 dc170611e62d1f1be1748f4eb7272f60 557 Hamap MF_01491 Ribonuclease J [rnj]. 6 557 43.2 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CWR44_RS08785 dc170611e62d1f1be1748f4eb7272f60 557 Pfam PF00753 Metallo-beta-lactamase superfamily 23 167 4.4E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS02395 c1062a5e7d54250e1a9de82352506068 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 58 1.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS02395 c1062a5e7d54250e1a9de82352506068 197 Pfam PF14278 Transcriptional regulator C-terminal region 90 165 5.2E-7 T 28-03-2018 CWR44_RS02395 c1062a5e7d54250e1a9de82352506068 197 Gene3D G3DSA:1.10.357.10 1 196 1.4E-17 T 28-03-2018 CWR44_RS02395 c1062a5e7d54250e1a9de82352506068 197 SUPERFAMILY SSF46689 4 72 7.18E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS12995 5f1d57ea00e1e5c693ea8b4fd3de4e79 139 Gene3D G3DSA:3.30.479.10 3 137 2.1E-37 T 28-03-2018 CWR44_RS12995 5f1d57ea00e1e5c693ea8b4fd3de4e79 139 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 16 106 1.2E-29 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CWR44_RS12995 5f1d57ea00e1e5c693ea8b4fd3de4e79 139 SUPERFAMILY SSF55620 12 135 6.67E-35 T 28-03-2018 CWR44_RS12995 5f1d57ea00e1e5c693ea8b4fd3de4e79 139 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 134 2.1E-30 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CWR44_RS12995 5f1d57ea00e1e5c693ea8b4fd3de4e79 139 PIRSF PIRSF006113 13 136 3.3E-25 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CWR44_RS06570 5f1d57ea00e1e5c693ea8b4fd3de4e79 139 Gene3D G3DSA:3.30.479.10 3 137 2.1E-37 T 28-03-2018 CWR44_RS06570 5f1d57ea00e1e5c693ea8b4fd3de4e79 139 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 16 106 1.2E-29 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CWR44_RS06570 5f1d57ea00e1e5c693ea8b4fd3de4e79 139 SUPERFAMILY SSF55620 12 135 6.67E-35 T 28-03-2018 CWR44_RS06570 5f1d57ea00e1e5c693ea8b4fd3de4e79 139 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 134 2.1E-30 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CWR44_RS06570 5f1d57ea00e1e5c693ea8b4fd3de4e79 139 PIRSF PIRSF006113 13 136 3.3E-25 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Gene3D G3DSA:3.90.199.10 31 212 3.4E-76 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 SUPERFAMILY SSF101904 497 797 1.31E-80 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Gene3D G3DSA:1.10.268.10 341 483 1.0E-45 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 29 468 9.9E-151 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 4 799 32.734 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 SMART SM00434 8 461 2.6E-255 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Gene3D G3DSA:3.30.1360.40 233 329 7.5E-31 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 5 742 0.0 T 28-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Gene3D G3DSA:2.120.10.90 497 798 2.8E-70 T 28-03-2018 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 606 649 5.3E-6 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 693 0.0034 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 547 594 0.011 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 502 536 0.11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 703 750 1.3 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CWR44_RS09800 6f99a0ed34ad3ffea977ce1d2e466b20 799 SUPERFAMILY SSF56719 28 481 1.22E-164 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CWR44_RS06730 1ce40eea2aa7a784f2bb6db87489ef51 307 Gene3D G3DSA:3.90.78.10 219 306 1.4E-26 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS06730 1ce40eea2aa7a784f2bb6db87489ef51 307 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 202 301 3.4E-29 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS06730 1ce40eea2aa7a784f2bb6db87489ef51 307 Gene3D G3DSA:3.30.43.10 17 88 6.9E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CWR44_RS06730 1ce40eea2aa7a784f2bb6db87489ef51 307 SUPERFAMILY SSF56176 6 197 3.64E-45 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CWR44_RS06730 1ce40eea2aa7a784f2bb6db87489ef51 307 Pfam PF01565 FAD binding domain 39 166 6.1E-27 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CWR44_RS06730 1ce40eea2aa7a784f2bb6db87489ef51 307 SUPERFAMILY SSF56194 199 304 5.89E-38 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS06730 1ce40eea2aa7a784f2bb6db87489ef51 307 Gene3D G3DSA:3.30.465.10 92 218 5.3E-36 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CWR44_RS06730 1ce40eea2aa7a784f2bb6db87489ef51 307 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 26 302 1.9E-72 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS06730 1ce40eea2aa7a784f2bb6db87489ef51 307 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 307 93.957 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS08165 81f4fd50239c31dadbe1d3e19fd868fe 246 Gene3D G3DSA:3.30.1330.30 1 98 9.8E-19 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWR44_RS08165 81f4fd50239c31dadbe1d3e19fd868fe 246 SUPERFAMILY SSF75217 99 244 8.5E-35 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR44_RS08165 81f4fd50239c31dadbe1d3e19fd868fe 246 SMART SM00967 31 100 2.8E-12 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWR44_RS08165 81f4fd50239c31dadbe1d3e19fd868fe 246 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 99 5.6E-10 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CWR44_RS08165 81f4fd50239c31dadbe1d3e19fd868fe 246 SUPERFAMILY SSF55315 3 99 4.12E-23 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWR44_RS08165 81f4fd50239c31dadbe1d3e19fd868fe 246 Gene3D G3DSA:3.40.1280.10 102 246 5.5E-36 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR44_RS08165 81f4fd50239c31dadbe1d3e19fd868fe 246 Pfam PF00588 SpoU rRNA Methylase family 107 242 1.6E-32 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 207 221 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 SUPERFAMILY SSF56655 2 252 1.83E-72 T 28-03-2018 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 Pfam PF00459 Inositol monophosphatase family 3 252 4.6E-57 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 Gene3D G3DSA:3.40.190.80 149 271 1.1E-26 T 28-03-2018 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 93 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CWR44_RS08055 23476366ef19819449dcf202834943ae 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 173 194 2.6E-37 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 36 56 2.6E-37 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 2.6E-37 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 2.6E-37 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 58 74 2.6E-37 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 204 228 2.6E-37 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS08055 23476366ef19819449dcf202834943ae 271 Gene3D G3DSA:3.30.540.10 1 148 6.4E-41 T 28-03-2018 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 3 410 29.331 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 SUPERFAMILY SSF54814 200 278 3.99E-29 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 Pfam PF13184 NusA-like KH domain 230 297 1.7E-28 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 Gene3D G3DSA:3.30.300.20 274 342 2.3E-15 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 SMART SM00322 230 302 0.19 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 SMART SM00322 303 384 0.4 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 6 342 1.9E-124 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 SUPERFAMILY SSF54814 279 342 4.84E-16 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 Gene3D G3DSA:2.40.50.140 137 198 1.2E-11 T 28-03-2018 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 SMART SM00316 134 200 1.6E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 Gene3D G3DSA:3.30.300.20 199 273 8.2E-34 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 SUPERFAMILY SSF50249 133 199 9.03E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 SUPERFAMILY SSF69705 4 126 3.14E-39 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 Gene3D G3DSA:3.30.1480.10 2 130 1.1E-44 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 Pfam PF08529 NusA N-terminal domain 5 125 2.9E-39 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CWR44_RS08740 d9ca0ca7e3010bc991a43e28b8074a67 410 Pfam PF00575 S1 RNA binding domain 133 196 1.7E-5 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS01375 6324a53caa85dc2a652a6e9744760d73 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 91 1.6E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWR44_RS01375 6324a53caa85dc2a652a6e9744760d73 331 SUPERFAMILY SSF51735 120 293 2.68E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS01375 6324a53caa85dc2a652a6e9744760d73 331 Gene3D G3DSA:3.40.50.720 164 301 3.7E-10 T 28-03-2018 CWR44_RS01375 6324a53caa85dc2a652a6e9744760d73 331 Pfam PF00107 Zinc-binding dehydrogenase 164 271 9.0E-10 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR44_RS01375 6324a53caa85dc2a652a6e9744760d73 331 SUPERFAMILY SSF50129 5 146 1.05E-40 T 28-03-2018 IPR011032 GroES-like CWR44_RS01375 6324a53caa85dc2a652a6e9744760d73 331 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 6 328 1.5E-130 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CWR44_RS01375 6324a53caa85dc2a652a6e9744760d73 331 SMART SM00829 16 327 2.4E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR44_RS01375 6324a53caa85dc2a652a6e9744760d73 331 Gene3D G3DSA:3.90.180.10 4 163 1.3E-35 T 28-03-2018 CWR44_RS01475 83ffa3f09920be52a6f082bc8764b43a 385 Gene3D G3DSA:1.20.1250.20 8 190 9.9E-22 T 28-03-2018 CWR44_RS01475 83ffa3f09920be52a6f082bc8764b43a 385 SUPERFAMILY SSF103473 10 381 3.53E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01475 83ffa3f09920be52a6f082bc8764b43a 385 Pfam PF07690 Major Facilitator Superfamily 15 342 2.8E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS01475 83ffa3f09920be52a6f082bc8764b43a 385 Gene3D G3DSA:1.20.1250.20 191 383 2.1E-28 T 28-03-2018 CWR44_RS05285 5a2a989427532b19c7f2754ca449809d 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CWR44_RS05285 5a2a989427532b19c7f2754ca449809d 256 PIRSF PIRSF005902 1 256 4.7E-85 T 28-03-2018 IPR001130 TatD family GO:0016788 CWR44_RS05285 5a2a989427532b19c7f2754ca449809d 256 Pfam PF01026 TatD related DNase 3 254 6.9E-84 T 28-03-2018 IPR001130 TatD family GO:0016788 CWR44_RS05285 5a2a989427532b19c7f2754ca449809d 256 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 190 206 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CWR44_RS05285 5a2a989427532b19c7f2754ca449809d 256 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 254 3.2E-91 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CWR44_RS05285 5a2a989427532b19c7f2754ca449809d 256 SUPERFAMILY SSF51556 2 255 9.54E-92 T 28-03-2018 IPR032466 Metal-dependent hydrolase CWR44_RS05285 5a2a989427532b19c7f2754ca449809d 256 Gene3D G3DSA:3.20.20.140 1 256 2.1E-92 T 28-03-2018 CWR44_RS10540 de3df264c7ba9022a81cc052a6e56ae6 445 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 6 343 1.1E-130 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CWR44_RS10540 de3df264c7ba9022a81cc052a6e56ae6 445 Gene3D G3DSA:2.40.50.140 14 101 1.2E-8 T 28-03-2018 CWR44_RS10540 de3df264c7ba9022a81cc052a6e56ae6 445 Pfam PF02601 Exonuclease VII, large subunit 124 435 4.1E-93 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CWR44_RS10540 de3df264c7ba9022a81cc052a6e56ae6 445 Pfam PF13742 OB-fold nucleic acid binding domain 5 100 1.8E-27 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CWR44_RS10540 de3df264c7ba9022a81cc052a6e56ae6 445 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 2 438 27.56 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CWR44_RS03465 0d989d79c29518ba8a8a9158fa8d399c 432 Gene3D G3DSA:2.40.50.100 5 79 7.2E-17 T 28-03-2018 CWR44_RS03465 0d989d79c29518ba8a8a9158fa8d399c 432 SUPERFAMILY SSF51230 3 94 6.94E-24 T 28-03-2018 IPR011053 Single hybrid motif CWR44_RS03465 0d989d79c29518ba8a8a9158fa8d399c 432 SUPERFAMILY SSF47005 133 177 8.24E-10 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS03465 0d989d79c29518ba8a8a9158fa8d399c 432 Gene3D G3DSA:4.10.320.10 130 192 2.4E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS03465 0d989d79c29518ba8a8a9158fa8d399c 432 Pfam PF02817 e3 binding domain 139 174 1.2E-10 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS03465 0d989d79c29518ba8a8a9158fa8d399c 432 Gene3D G3DSA:3.30.559.10 193 432 1.0E-68 T 28-03-2018 CWR44_RS03465 0d989d79c29518ba8a8a9158fa8d399c 432 SUPERFAMILY SSF52777 208 432 2.05E-65 T 28-03-2018 CWR44_RS03465 0d989d79c29518ba8a8a9158fa8d399c 432 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 209 431 2.3E-71 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CWR44_RS03465 0d989d79c29518ba8a8a9158fa8d399c 432 Pfam PF00364 Biotin-requiring enzyme 4 76 1.5E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CWR44_RS02635 3fa9f44f1c95ac3857ef722eee456ca9 265 Gene3D G3DSA:3.30.1450.10 145 258 5.0E-5 T 28-03-2018 CWR44_RS02635 3fa9f44f1c95ac3857ef722eee456ca9 265 Pfam PF13240 zinc-ribbon domain 3 25 1.7E-7 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CWR44_RS02635 3fa9f44f1c95ac3857ef722eee456ca9 265 Gene3D G3DSA:2.20.28.20 3 29 4.1E-4 T 28-03-2018 CWR44_RS06365 813983f3f904da4b4c504667e1a5fb38 715 SMART SM00342 166 249 2.7E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS06365 813983f3f904da4b4c504667e1a5fb38 715 Gene3D G3DSA:1.10.10.60 140 202 3.9E-7 T 28-03-2018 CWR44_RS06365 813983f3f904da4b4c504667e1a5fb38 715 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 218 233 3.6E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR44_RS06365 813983f3f904da4b4c504667e1a5fb38 715 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 233 249 3.6E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CWR44_RS06365 813983f3f904da4b4c504667e1a5fb38 715 Pfam PF12833 Helix-turn-helix domain 172 249 1.0E-13 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS06365 813983f3f904da4b4c504667e1a5fb38 715 Gene3D G3DSA:1.10.10.60 203 250 6.9E-9 T 28-03-2018 CWR44_RS06365 813983f3f904da4b4c504667e1a5fb38 715 SUPERFAMILY SSF46689 203 249 2.42E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS07535 9b20b6a0bd5c93426c798ee479cea4f4 193 Pfam PF01928 CYTH domain 5 185 2.2E-23 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CWR44_RS07535 9b20b6a0bd5c93426c798ee479cea4f4 193 Gene3D G3DSA:2.40.320.10 2 193 7.3E-31 T 28-03-2018 CWR44_RS07535 9b20b6a0bd5c93426c798ee479cea4f4 193 PIRSF PIRSF012526 1 192 1.3E-67 T 28-03-2018 IPR009195 Uncharacterised protein family YjbK CWR44_RS07535 9b20b6a0bd5c93426c798ee479cea4f4 193 SUPERFAMILY SSF55154 4 186 3.11E-30 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CWR44_RS07535 9b20b6a0bd5c93426c798ee479cea4f4 193 SMART SM01118 4 191 3.4E-20 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CWR44_RS08185 2387cdfdf615f3756c6023fae39f246a 88 SUPERFAMILY SSF102829 7 86 1.15E-20 T 28-03-2018 IPR007838 Cell division protein ZapA-like CWR44_RS08185 2387cdfdf615f3756c6023fae39f246a 88 Pfam PF05164 Cell division protein ZapA 8 86 8.3E-16 T 28-03-2018 IPR007838 Cell division protein ZapA-like CWR44_RS09370 7f46402fbd7039eb0838a2f4b889eda3 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 20.155 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS09370 7f46402fbd7039eb0838a2f4b889eda3 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS09370 7f46402fbd7039eb0838a2f4b889eda3 49 SUPERFAMILY SSF57829 1 49 9.77E-21 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CWR44_RS09370 7f46402fbd7039eb0838a2f4b889eda3 49 Pfam PF00471 Ribosomal protein L33 3 49 9.9E-25 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS09370 7f46402fbd7039eb0838a2f4b889eda3 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 4.3E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04685 e51f2e0d0ea0ec3efd11a2092582afc6 315 SUPERFAMILY SSF161111 16 216 1.96E-56 T 28-03-2018 CWR44_RS04685 e51f2e0d0ea0ec3efd11a2092582afc6 315 Pfam PF01545 Cation efflux family 22 215 6.4E-49 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR44_RS04685 e51f2e0d0ea0ec3efd11a2092582afc6 315 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 296 6.8E-90 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR44_RS04685 e51f2e0d0ea0ec3efd11a2092582afc6 315 Gene3D G3DSA:1.20.1510.10 18 213 1.1E-56 T 28-03-2018 CWR44_RS04685 e51f2e0d0ea0ec3efd11a2092582afc6 315 Gene3D G3DSA:3.30.70.1350 214 297 3.6E-15 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR44_RS04685 e51f2e0d0ea0ec3efd11a2092582afc6 315 SUPERFAMILY SSF160240 221 297 1.7E-11 T 28-03-2018 CWR44_RS01530 28ea94766be6f79de344a1952a6c7c32 241 SUPERFAMILY SSF53800 8 236 4.03E-27 T 28-03-2018 CWR44_RS01530 28ea94766be6f79de344a1952a6c7c32 241 Gene3D G3DSA:3.40.50.1400 2 121 5.5E-22 T 28-03-2018 CWR44_RS01530 28ea94766be6f79de344a1952a6c7c32 241 Gene3D G3DSA:3.40.50.1400 122 239 5.0E-8 T 28-03-2018 CWR44_RS01530 28ea94766be6f79de344a1952a6c7c32 241 Pfam PF01903 CbiX 12 115 4.3E-24 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 353 5.5E-84 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 SUPERFAMILY SSF52283 305 360 9.35E-67 T 28-03-2018 CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 SUPERFAMILY SSF52283 1 136 9.35E-67 T 28-03-2018 CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 28-03-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 9.1E-171 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 SMART SM01002 148 297 3.8E-87 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 SUPERFAMILY SSF51735 136 303 3.25E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 Gene3D G3DSA:3.40.50.720 1 186 7.4E-42 T 28-03-2018 CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 Gene3D G3DSA:3.40.50.720 187 371 1.6E-46 T 28-03-2018 CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 2.8E-45 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 SMART SM01003 4 136 1.1E-73 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CWR44_RS11405 d860648565b060fafde8bfb95d8d5f66 373 PIRSF PIRSF000183 1 371 4.4E-205 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CWR44_RS08950 e0563a9606934aaeca7f487a6d0a997d 121 SUPERFAMILY SSF46955 13 84 4.03E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CWR44_RS08950 e0563a9606934aaeca7f487a6d0a997d 121 SMART SM00422 13 81 9.5E-26 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS08950 e0563a9606934aaeca7f487a6d0a997d 121 Gene3D G3DSA:1.10.1660.10 2 103 2.0E-22 T 28-03-2018 CWR44_RS08950 e0563a9606934aaeca7f487a6d0a997d 121 Pfam PF13411 MerR HTH family regulatory protein 13 79 6.3E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS09770 0dfcb9b321aab31785881564ef809f05 545 ProSitePatterns PS01303 BCCT family of transporters signature. 319 328 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CWR44_RS09770 0dfcb9b321aab31785881564ef809f05 545 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 55 503 1.9E-155 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CWR44_RS09770 0dfcb9b321aab31785881564ef809f05 545 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 17 502 4.7E-183 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CWR44_RS09160 fbbce7ecbe408990371686fea90af8a2 251 Pfam PF04630 Phage tail tube protein 7 196 1.6E-13 T 28-03-2018 IPR006724 Phage tail tube protein 1 CWR44_RS09160 fbbce7ecbe408990371686fea90af8a2 251 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 7 190 6.6E-20 T 28-03-2018 IPR006490 Phage major tail protein, phi13 family CWR44_RS11695 db73dacff0ed3cdcc37d7f0912189ad5 133 TIGRFAM TIGR01889 Staph_reg_Sar: staphylococcal accessory regulator family 14 116 1.1E-22 T 28-03-2018 IPR010166 Transcriptional regulator SarA/Rot GO:0006355 CWR44_RS11695 db73dacff0ed3cdcc37d7f0912189ad5 133 SMART SM00347 28 132 0.0027 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS11695 db73dacff0ed3cdcc37d7f0912189ad5 133 SUPERFAMILY SSF46785 8 122 1.36E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11695 db73dacff0ed3cdcc37d7f0912189ad5 133 Pfam PF01047 MarR family 35 93 1.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS11695 db73dacff0ed3cdcc37d7f0912189ad5 133 Gene3D G3DSA:1.10.10.10 3 128 3.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS05700 e6faf2fcc9cf0e1bb0e804dc65b2a6f5 318 Gene3D G3DSA:3.90.25.10 218 315 2.4E-4 T 28-03-2018 CWR44_RS05700 e6faf2fcc9cf0e1bb0e804dc65b2a6f5 318 Gene3D G3DSA:3.40.50.720 1 217 8.1E-28 T 28-03-2018 CWR44_RS05700 e6faf2fcc9cf0e1bb0e804dc65b2a6f5 318 SUPERFAMILY SSF51735 1 314 1.64E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS05700 e6faf2fcc9cf0e1bb0e804dc65b2a6f5 318 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 231 3.3E-23 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CWR44_RS07395 ebd558d74138ca1fa132cba4b6f5abde 190 Pfam PF00717 Peptidase S24-like 31 99 2.0E-18 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR44_RS07395 ebd558d74138ca1fa132cba4b6f5abde 190 ProSitePatterns PS00501 Signal peptidases I serine active site. 34 41 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CWR44_RS07395 ebd558d74138ca1fa132cba4b6f5abde 190 SUPERFAMILY SSF51306 25 183 6.54E-49 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR44_RS07395 ebd558d74138ca1fa132cba4b6f5abde 190 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 8 177 7.7E-53 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS07395 ebd558d74138ca1fa132cba4b6f5abde 190 Gene3D G3DSA:2.10.109.10 21 189 2.6E-43 T 28-03-2018 CWR44_RS07395 ebd558d74138ca1fa132cba4b6f5abde 190 ProSitePatterns PS00761 Signal peptidases I signature 3. 142 155 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CWR44_RS07395 ebd558d74138ca1fa132cba4b6f5abde 190 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 7.7E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS07395 ebd558d74138ca1fa132cba4b6f5abde 190 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 25 41 7.7E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS07395 ebd558d74138ca1fa132cba4b6f5abde 190 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 75 87 7.7E-22 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS07395 ebd558d74138ca1fa132cba4b6f5abde 190 ProSitePatterns PS00760 Signal peptidases I lysine active site. 77 89 - T 28-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CWR44_RS05690 c5c512d23d83913381bee1817106fafd 319 PIRSF PIRSF001439 1 319 8.8E-90 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CWR44_RS05690 c5c512d23d83913381bee1817106fafd 319 Gene3D G3DSA:3.30.1780.10 1 135 7.0E-46 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CWR44_RS05690 c5c512d23d83913381bee1817106fafd 319 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 3 315 1.7E-81 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CWR44_RS05690 c5c512d23d83913381bee1817106fafd 319 Gene3D G3DSA:3.40.50.720 136 297 1.5E-33 T 28-03-2018 CWR44_RS05690 c5c512d23d83913381bee1817106fafd 319 SUPERFAMILY SSF51735 1 315 3.26E-94 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS12380 3d80addc0587aada8e34a543d2a8f0b1 475 Pfam PF02637 GatB domain 325 472 1.2E-56 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CWR44_RS12380 3d80addc0587aada8e34a543d2a8f0b1 475 Gene3D G3DSA:1.10.10.410 412 473 1.7E-25 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CWR44_RS12380 3d80addc0587aada8e34a543d2a8f0b1 475 SUPERFAMILY SSF89095 294 399 1.05E-34 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CWR44_RS12380 3d80addc0587aada8e34a543d2a8f0b1 475 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 141 155 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CWR44_RS12380 3d80addc0587aada8e34a543d2a8f0b1 475 SUPERFAMILY SSF55931 4 293 1.24E-122 T 28-03-2018 CWR44_RS12380 3d80addc0587aada8e34a543d2a8f0b1 475 SMART SM00845 325 472 1.6E-76 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CWR44_RS12380 3d80addc0587aada8e34a543d2a8f0b1 475 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 472 8.6E-181 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CWR44_RS12380 3d80addc0587aada8e34a543d2a8f0b1 475 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 473 38.779 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CWR44_RS12380 3d80addc0587aada8e34a543d2a8f0b1 475 Pfam PF02934 GatB/GatE catalytic domain 5 285 1.2E-112 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CWR44_RS08285 5a65cef18fa1fed0b65954f726042004 147 Hamap MF_00824 Uncharacterized N-acetyltransferase . 1 146 38.961 T 28-03-2018 IPR017274 Putative N-acetyltransferase YlbP CWR44_RS08285 5a65cef18fa1fed0b65954f726042004 147 SUPERFAMILY SSF55729 27 107 8.26E-7 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS08285 5a65cef18fa1fed0b65954f726042004 147 PIRSF PIRSF037732 1 147 1.5E-52 T 28-03-2018 IPR017274 Putative N-acetyltransferase YlbP CWR44_RS08285 5a65cef18fa1fed0b65954f726042004 147 Gene3D G3DSA:3.40.630.30 1 147 1.3E-12 T 28-03-2018 CWR44_RS06710 9e430cdb1a0aa7e42f3e9f5d51a99501 260 Gene3D G3DSA:3.40.50.300 1 243 1.3E-58 T 28-03-2018 CWR44_RS06710 9e430cdb1a0aa7e42f3e9f5d51a99501 260 Pfam PF00005 ABC transporter 17 164 2.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06710 9e430cdb1a0aa7e42f3e9f5d51a99501 260 SMART SM00382 26 213 5.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS06710 9e430cdb1a0aa7e42f3e9f5d51a99501 260 SUPERFAMILY SSF52540 2 226 1.98E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS13020 a9316cefca90db9d14fa96ed98f42426 282 SUPERFAMILY SSF46548 142 267 1.17E-26 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CWR44_RS13020 a9316cefca90db9d14fa96ed98f42426 282 Gene3D G3DSA:3.10.20.30 26 138 1.1E-25 T 28-03-2018 IPR012675 Beta-grasp domain CWR44_RS13020 a9316cefca90db9d14fa96ed98f42426 282 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 38 260 7.6E-41 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS13020 a9316cefca90db9d14fa96ed98f42426 282 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 36 144 1.5E-28 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS13020 a9316cefca90db9d14fa96ed98f42426 282 SUPERFAMILY SSF54292 33 139 2.06E-22 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR44_RS13020 a9316cefca90db9d14fa96ed98f42426 282 Gene3D G3DSA:1.10.1060.10 139 270 2.0E-18 T 28-03-2018 CWR44_RS13020 a9316cefca90db9d14fa96ed98f42426 282 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 182 193 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR44_RS13020 a9316cefca90db9d14fa96ed98f42426 282 Pfam PF13183 4Fe-4S dicluster domain 178 253 4.1E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR44_RS08225 a9316cefca90db9d14fa96ed98f42426 282 SUPERFAMILY SSF46548 142 267 1.17E-26 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CWR44_RS08225 a9316cefca90db9d14fa96ed98f42426 282 Gene3D G3DSA:3.10.20.30 26 138 1.1E-25 T 28-03-2018 IPR012675 Beta-grasp domain CWR44_RS08225 a9316cefca90db9d14fa96ed98f42426 282 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 38 260 7.6E-41 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS08225 a9316cefca90db9d14fa96ed98f42426 282 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 36 144 1.5E-28 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS08225 a9316cefca90db9d14fa96ed98f42426 282 SUPERFAMILY SSF54292 33 139 2.06E-22 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CWR44_RS08225 a9316cefca90db9d14fa96ed98f42426 282 Gene3D G3DSA:1.10.1060.10 139 270 2.0E-18 T 28-03-2018 CWR44_RS08225 a9316cefca90db9d14fa96ed98f42426 282 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 182 193 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CWR44_RS08225 a9316cefca90db9d14fa96ed98f42426 282 Pfam PF13183 4Fe-4S dicluster domain 178 253 4.1E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CWR44_RS08515 a691ce2e1c616d9aa942c122c311fdca 214 SUPERFAMILY SSF51366 1 213 7.4E-73 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR44_RS08515 a691ce2e1c616d9aa942c122c311fdca 214 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR44_RS08515 a691ce2e1c616d9aa942c122c311fdca 214 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 1.1E-79 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR44_RS08515 a691ce2e1c616d9aa942c122c311fdca 214 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 212 5.3E-86 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR44_RS08515 a691ce2e1c616d9aa942c122c311fdca 214 Gene3D G3DSA:3.20.20.70 1 214 2.3E-81 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS08515 a691ce2e1c616d9aa942c122c311fdca 214 PIRSF PIRSF001461 1 214 2.3E-87 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR44_RS08515 a691ce2e1c616d9aa942c122c311fdca 214 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR44_RS03125 4d243b93bf1bf2d2395f466edc6d15f3 379 Gene3D G3DSA:3.20.20.370 93 373 2.2E-21 T 28-03-2018 CWR44_RS03125 4d243b93bf1bf2d2395f466edc6d15f3 379 Pfam PF01522 Polysaccharide deacetylase 241 303 8.1E-6 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CWR44_RS03125 4d243b93bf1bf2d2395f466edc6d15f3 379 SUPERFAMILY SSF88713 89 146 1.59E-15 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR44_RS03125 4d243b93bf1bf2d2395f466edc6d15f3 379 SUPERFAMILY SSF88713 184 318 1.59E-15 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR44_RS05345 25af5026b826394650344919ccb18446 1169 Gene3D G3DSA:3.40.50.300 805 972 5.9E-25 T 28-03-2018 CWR44_RS05345 25af5026b826394650344919ccb18446 1169 Gene3D G3DSA:3.40.50.300 463 787 1.4E-37 T 28-03-2018 CWR44_RS05345 25af5026b826394650344919ccb18446 1169 SUPERFAMILY SSF141259 487 564 2.75E-25 T 28-03-2018 IPR003711 CarD-like/TRCF domain CWR44_RS05345 25af5026b826394650344919ccb18446 1169 SMART SM00487 616 806 7.1E-36 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS05345 25af5026b826394650344919ccb18446 1169 Pfam PF03461 TRCF domain 1022 1113 3.6E-26 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CWR44_RS05345 25af5026b826394650344919ccb18446 1169 SUPERFAMILY SSF52540 540 799 2.81E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05345 25af5026b826394650344919ccb18446 1169 Pfam PF02559 CarD-like/TRCF domain 496 591 7.6E-32 T 28-03-2018 IPR003711 CarD-like/TRCF domain CWR44_RS05345 25af5026b826394650344919ccb18446 1169 SMART SM00982 1021 1121 5.1E-36 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CWR44_RS05345 25af5026b826394650344919ccb18446 1169 SUPERFAMILY SSF52540 374 482 6.39E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05345 25af5026b826394650344919ccb18446 1169 SUPERFAMILY SSF143517 1010 1160 5.75E-32 T 28-03-2018 CWR44_RS05345 25af5026b826394650344919ccb18446 1169 SUPERFAMILY SSF52540 23 366 1.38E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05345 25af5026b826394650344919ccb18446 1169 Pfam PF00271 Helicase conserved C-terminal domain 820 925 3.4E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS05345 25af5026b826394650344919ccb18446 1169 Pfam PF00270 DEAD/DEAH box helicase 621 780 3.2E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR44_RS05345 25af5026b826394650344919ccb18446 1169 SUPERFAMILY SSF52540 798 1004 7.2E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05345 25af5026b826394650344919ccb18446 1169 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 37 1125 29.315 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CWR44_RS05345 25af5026b826394650344919ccb18446 1169 SMART SM01058 495 592 2.0E-47 T 28-03-2018 IPR003711 CarD-like/TRCF domain CWR44_RS05345 25af5026b826394650344919ccb18446 1169 SMART SM00490 839 926 1.0E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS05345 25af5026b826394650344919ccb18446 1169 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 156 1094 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CWR44_RS03410 f3faaf63eb999828546cf0fa895f32b8 1089 SUPERFAMILY SSF53335 903 1064 3.32E-8 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS03410 f3faaf63eb999828546cf0fa895f32b8 1089 Pfam PF04851 Type III restriction enzyme, res subunit 130 308 7.6E-13 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWR44_RS03410 f3faaf63eb999828546cf0fa895f32b8 1089 SUPERFAMILY SSF52540 271 307 1.01E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03410 f3faaf63eb999828546cf0fa895f32b8 1089 SUPERFAMILY SSF52540 410 529 1.01E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03410 f3faaf63eb999828546cf0fa895f32b8 1089 Gene3D G3DSA:3.40.50.150 924 1075 7.0E-6 T 28-03-2018 CWR44_RS03410 f3faaf63eb999828546cf0fa895f32b8 1089 SMART SM00487 128 342 0.0022 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS03410 f3faaf63eb999828546cf0fa895f32b8 1089 SMART SM00974 26 113 0.0026 T 28-03-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding CWR44_RS03410 f3faaf63eb999828546cf0fa895f32b8 1089 Gene3D G3DSA:3.40.50.300 384 534 2.2E-4 T 28-03-2018 CWR44_RS03410 f3faaf63eb999828546cf0fa895f32b8 1089 SUPERFAMILY SSF52540 108 309 1.06E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03410 f3faaf63eb999828546cf0fa895f32b8 1089 Gene3D G3DSA:3.40.50.300 118 335 2.5E-15 T 28-03-2018 CWR44_RS02565 1d6e082f456356af6f29bbe16ee9ec8e 184 SUPERFAMILY SSF46785 11 161 1.49E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02565 1d6e082f456356af6f29bbe16ee9ec8e 184 Gene3D G3DSA:1.10.10.10 3 157 3.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02565 1d6e082f456356af6f29bbe16ee9ec8e 184 PIRSF PIRSF006707 1 183 2.3E-48 T 28-03-2018 IPR026282 DNA-binding protein, MJ1563 type CWR44_RS06590 e09e5404a3529dee6d73f45191f5028f 202 Gene3D G3DSA:3.30.470.10 1 75 6.5E-17 T 28-03-2018 CWR44_RS06590 e09e5404a3529dee6d73f45191f5028f 202 Pfam PF01063 Amino-transferase class IV 3 200 1.1E-30 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR44_RS06590 e09e5404a3529dee6d73f45191f5028f 202 Gene3D G3DSA:3.20.10.10 76 195 1.5E-14 T 28-03-2018 CWR44_RS06590 e09e5404a3529dee6d73f45191f5028f 202 SUPERFAMILY SSF56752 2 199 1.26E-33 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR44_RS02830 f88649ec79b406ddf9a0f34c9583fe11 331 Pfam PF13377 Periplasmic binding protein-like domain 168 331 4.9E-33 T 28-03-2018 CWR44_RS02830 f88649ec79b406ddf9a0f34c9583fe11 331 SMART SM00354 1 71 6.5E-35 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS02830 f88649ec79b406ddf9a0f34c9583fe11 331 Gene3D G3DSA:3.40.50.2300 175 314 3.0E-31 T 28-03-2018 CWR44_RS02830 f88649ec79b406ddf9a0f34c9583fe11 331 Gene3D G3DSA:1.10.260.40 2 55 1.9E-21 T 28-03-2018 CWR44_RS02830 f88649ec79b406ddf9a0f34c9583fe11 331 SUPERFAMILY SSF53822 61 331 3.34E-61 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWR44_RS02830 f88649ec79b406ddf9a0f34c9583fe11 331 Gene3D G3DSA:3.40.50.2300 56 174 3.8E-24 T 28-03-2018 CWR44_RS02830 f88649ec79b406ddf9a0f34c9583fe11 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.3E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS02830 f88649ec79b406ddf9a0f34c9583fe11 331 SUPERFAMILY SSF47413 1 59 4.3E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS08735 a3fe8a2c0e69fe790157db6a1b7592f5 155 Pfam PF02576 RimP N-terminal domain 11 83 2.9E-24 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CWR44_RS08735 a3fe8a2c0e69fe790157db6a1b7592f5 155 Gene3D G3DSA:2.30.30.180 87 153 2.2E-19 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CWR44_RS08735 a3fe8a2c0e69fe790157db6a1b7592f5 155 SUPERFAMILY SSF74942 84 153 3.01E-18 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CWR44_RS08735 a3fe8a2c0e69fe790157db6a1b7592f5 155 Pfam PF17384 RimP C-terminal SH3 domain 86 150 3.9E-17 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CWR44_RS08735 a3fe8a2c0e69fe790157db6a1b7592f5 155 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 155 21.985 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CWR44_RS08735 a3fe8a2c0e69fe790157db6a1b7592f5 155 SUPERFAMILY SSF75420 2 83 6.02E-24 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CWR44_RS08735 a3fe8a2c0e69fe790157db6a1b7592f5 155 Gene3D G3DSA:3.30.300.70 1 80 7.6E-25 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CWR44_RS03005 c4d7d18ede17de830a4a15c9e0d07387 524 TIGRFAM TIGR03713 acc_sec_asp1: accessory Sec system protein Asp1 1 517 7.8E-223 T 28-03-2018 IPR022372 Accessory secretory system protein Asp1 GO:0015031 CWR44_RS03005 c4d7d18ede17de830a4a15c9e0d07387 524 Pfam PF16993 Accessory Sec system protein Asp1 1 515 1.4E-97 T 28-03-2018 IPR022372 Accessory secretory system protein Asp1 GO:0015031 CWR44_RS05975 b37b53bfdacc9ed59838f11a04db7e4f 311 PRINTS PR00069 Aldo-keto reductase signature 241 265 3.5E-20 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS05975 b37b53bfdacc9ed59838f11a04db7e4f 311 PRINTS PR00069 Aldo-keto reductase signature 111 129 3.5E-20 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS05975 b37b53bfdacc9ed59838f11a04db7e4f 311 PRINTS PR00069 Aldo-keto reductase signature 45 69 3.5E-20 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS05975 b37b53bfdacc9ed59838f11a04db7e4f 311 PRINTS PR00069 Aldo-keto reductase signature 142 159 3.5E-20 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS05975 b37b53bfdacc9ed59838f11a04db7e4f 311 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 142 159 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWR44_RS05975 b37b53bfdacc9ed59838f11a04db7e4f 311 SUPERFAMILY SSF51430 5 308 7.46E-92 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS05975 b37b53bfdacc9ed59838f11a04db7e4f 311 Gene3D G3DSA:3.20.20.100 3 310 1.9E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS05975 b37b53bfdacc9ed59838f11a04db7e4f 311 Pfam PF00248 Aldo/keto reductase family 16 307 1.7E-76 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS11650 a90ec0df29690d32cde32a1ad08b72a1 545 PIRSF PIRSF038958 2 540 1.5E-90 T 28-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CWR44_RS11650 a90ec0df29690d32cde32a1ad08b72a1 545 Pfam PF01943 Polysaccharide biosynthesis protein 8 325 3.4E-29 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CWR44_RS11650 a90ec0df29690d32cde32a1ad08b72a1 545 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 377 524 3.6E-25 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CWR44_RS09655 f5002a97a5251449c4f57d27e82b3181 215 Pfam PF06810 Phage minor structural protein GP20 16 169 1.1E-31 T 28-03-2018 IPR009636 Capsid assembly scaffolding protein GO:0019069|GO:0046806 CWR44_RS09655 f5002a97a5251449c4f57d27e82b3181 215 Gene3D G3DSA:1.20.5.320 8 115 4.1E-5 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF04650 YSIRK type signal peptide 5 26 5.3E-8 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.1270.90 545 620 7.6E-6 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 4 37 5.9E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 2001 2059 3.8E-4 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1231 1288 4.2E-5 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1539 1599 2.9E-4 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1693 1750 1.6E-5 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1385 1442 1.0E-5 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 2078 2154 0.28 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1924 1983 9.9E-5 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1847 1904 7.9E-4 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1077 1144 4.8E-4 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1616 1683 2.4E-4 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1462 1521 0.044 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1154 1211 1.6E-5 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1308 1370 3.1E-5 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1000 1059 9.8E-4 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 1770 1829 3.9E-5 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 923 980 6.1E-4 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:1.20.5.420 846 903 8.2E-4 T 28-03-2018 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 919 994 8.4E-22 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1304 1379 1.9E-20 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1766 1841 6.3E-23 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 766 839 2.1E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1381 1456 1.8E-23 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1073 1148 2.3E-22 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1997 2072 3.7E-20 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1150 1225 3.5E-22 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1920 1995 5.6E-22 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 2074 2148 4.2E-15 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1458 1533 1.4E-18 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 842 917 1.7E-21 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1843 1918 2.7E-20 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1227 1302 9.0E-22 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 2151 2224 1.5E-7 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1535 1610 2.0E-22 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1689 1764 3.5E-22 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 689 762 1.3E-15 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 612 684 1.2E-9 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 996 1071 2.6E-22 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Pfam PF07564 Domain of Unknown Function (DUF1542) 1612 1687 2.4E-21 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 TIGRFAM TIGR04263 SasC_Mrp_aggreg: SasC/Mrp/FmtB intercellular aggregation domain 161 555 4.3E-133 T 28-03-2018 IPR026359 SasC/Mrp/FmtB intercellular aggregation domain CWR44_RS11660 5276984ae539086d30e91971e30fe77a 2378 Gene3D G3DSA:2.60.40.1170 382 494 3.0E-7 T 28-03-2018 CWR44_RS06635 1db5759dbe4ddbc04a3574ec7b4db95e 322 SMART SM00382 26 212 6.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS06635 1db5759dbe4ddbc04a3574ec7b4db95e 322 Pfam PF00005 ABC transporter 18 163 7.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06635 1db5759dbe4ddbc04a3574ec7b4db95e 322 SUPERFAMILY SSF52540 1 238 1.4E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06635 1db5759dbe4ddbc04a3574ec7b4db95e 322 Gene3D G3DSA:3.40.50.300 1 307 7.5E-80 T 28-03-2018 CWR44_RS06635 1db5759dbe4ddbc04a3574ec7b4db95e 322 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS11735 abb3b34873611396e5e252ea1a39c9d8 347 SUPERFAMILY SSF53927 4 138 3.44E-34 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR44_RS11735 abb3b34873611396e5e252ea1a39c9d8 347 Gene3D G3DSA:3.40.430.10 122 343 9.4E-49 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CWR44_RS11735 abb3b34873611396e5e252ea1a39c9d8 347 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 5 339 7.4E-93 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CWR44_RS11735 abb3b34873611396e5e252ea1a39c9d8 347 PIRSF PIRSF006769 1 347 9.3E-95 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CWR44_RS11735 abb3b34873611396e5e252ea1a39c9d8 347 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 48 86 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWR44_RS11735 abb3b34873611396e5e252ea1a39c9d8 347 SUPERFAMILY SSF53597 141 344 7.85E-46 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CWR44_RS11735 abb3b34873611396e5e252ea1a39c9d8 347 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 97 3.6E-17 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWR44_RS11735 abb3b34873611396e5e252ea1a39c9d8 347 Pfam PF01872 RibD C-terminal domain 142 316 1.7E-38 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CWR44_RS11735 abb3b34873611396e5e252ea1a39c9d8 347 Gene3D G3DSA:3.40.140.10 1 121 1.3E-25 T 28-03-2018 CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 SMART SM00387 381 488 3.8E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 Gene3D G3DSA:1.10.287.130 271 333 1.8E-10 T 28-03-2018 CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 484 6.8E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 Pfam PF00512 His Kinase A (phospho-acceptor) domain 279 333 5.5E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 SMART SM00388 278 340 2.4E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 SUPERFAMILY SSF47384 274 341 6.67E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 Gene3D G3DSA:3.30.565.10 334 485 3.0E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 SUPERFAMILY SSF55874 332 484 8.12E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 PRINTS PR01780 Lantibiotic regulatory protein signature 147 163 1.5E-6 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 PRINTS PR01780 Lantibiotic regulatory protein signature 377 392 1.5E-6 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWR44_RS01790 c7f20c2a471018b2c8a5278ecc87261b 488 PRINTS PR01780 Lantibiotic regulatory protein signature 287 303 1.5E-6 T 28-03-2018 IPR008358 Signal transduction histidine kinase/phosphatase, lantibiotic regulatory protein MprB GO:0000155|GO:0000160|GO:0004673|GO:0016020 CWR44_RS03825 c9db7a0c3a5a5b6d1ef9bbc0fdcae184 211 SMART SM00382 25 210 1.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03825 c9db7a0c3a5a5b6d1ef9bbc0fdcae184 211 Gene3D G3DSA:3.40.50.300 1 204 2.0E-49 T 28-03-2018 CWR44_RS03825 c9db7a0c3a5a5b6d1ef9bbc0fdcae184 211 SUPERFAMILY SSF52540 2 197 2.53E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03825 c9db7a0c3a5a5b6d1ef9bbc0fdcae184 211 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS03825 c9db7a0c3a5a5b6d1ef9bbc0fdcae184 211 Pfam PF00005 ABC transporter 21 163 5.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS02305 287e0c8933df84208f30dd86147833a5 238 Gene3D G3DSA:1.10.530.10 83 238 4.1E-6 T 28-03-2018 CWR44_RS02305 287e0c8933df84208f30dd86147833a5 238 SUPERFAMILY SSF53955 169 203 1.41E-6 T 28-03-2018 IPR023346 Lysozyme-like domain CWR44_RS02560 1d124a14ab5621d9ecf376d040c19f0b 496 Pfam PF00171 Aldehyde dehydrogenase family 17 482 4.5E-174 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS02560 1d124a14ab5621d9ecf376d040c19f0b 496 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS02560 1d124a14ab5621d9ecf376d040c19f0b 496 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 12 478 8.1E-233 T 28-03-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 CWR44_RS02560 1d124a14ab5621d9ecf376d040c19f0b 496 SUPERFAMILY SSF53720 9 488 9.82E-169 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR44_RS02560 1d124a14ab5621d9ecf376d040c19f0b 496 Gene3D G3DSA:3.40.309.10 271 468 9.3E-75 T 28-03-2018 CWR44_RS02560 1d124a14ab5621d9ecf376d040c19f0b 496 Gene3D G3DSA:3.40.605.10 3 270 9.0E-95 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS02560 1d124a14ab5621d9ecf376d040c19f0b 496 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS12445 cbe269c311c3828fb370e0e967564efc 489 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 155 335 3.8E-9 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CWR44_RS12445 cbe269c311c3828fb370e0e967564efc 489 Gene3D G3DSA:3.20.140.10 7 387 9.4E-125 T 28-03-2018 CWR44_RS12445 cbe269c311c3828fb370e0e967564efc 489 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 464 4.7E-179 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CWR44_RS12445 cbe269c311c3828fb370e0e967564efc 489 PIRSF PIRSF000484 3 480 9.3E-149 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CWR44_RS12445 cbe269c311c3828fb370e0e967564efc 489 SUPERFAMILY SSF54675 5 138 1.62E-46 T 28-03-2018 CWR44_RS12445 cbe269c311c3828fb370e0e967564efc 489 SUPERFAMILY SSF51690 139 478 8.83E-131 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CWR44_RS05085 1e03e0dab2e2120fb116f0daae5d3272 243 Pfam PF12146 Serine aminopeptidase, S33 15 224 9.5E-14 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CWR44_RS05085 1e03e0dab2e2120fb116f0daae5d3272 243 PIRSF PIRSF017388 1 243 2.3E-70 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 CWR44_RS05085 1e03e0dab2e2120fb116f0daae5d3272 243 Gene3D G3DSA:3.40.50.1820 1 242 3.1E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS05085 1e03e0dab2e2120fb116f0daae5d3272 243 SUPERFAMILY SSF53474 164 241 1.11E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS05085 1e03e0dab2e2120fb116f0daae5d3272 243 SUPERFAMILY SSF53474 13 136 1.11E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS00560 10440b0aba63939bb8452d1b091c301b 178 Gene3D G3DSA:1.20.1640.10 2 82 5.1E-4 T 28-03-2018 CWR44_RS10210 f037e722c595aae5d9d0d6832d8a00a3 112 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 7 110 1.5E-21 T 28-03-2018 IPR014913 Protein of unknown function DUF1798 CWR44_RS10210 f037e722c595aae5d9d0d6832d8a00a3 112 SUPERFAMILY SSF140415 5 111 1.44E-31 T 28-03-2018 IPR023351 YppE-like domain CWR44_RS10210 f037e722c595aae5d9d0d6832d8a00a3 112 Gene3D G3DSA:1.20.120.440 3 112 1.8E-25 T 28-03-2018 IPR023351 YppE-like domain CWR44_RS05570 f398107d1018a04fb51bfbf13d224d0e 128 Pfam PF00636 Ribonuclease III domain 10 109 4.6E-16 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR44_RS05570 f398107d1018a04fb51bfbf13d224d0e 128 Gene3D G3DSA:1.10.1520.10 4 128 3.4E-19 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR44_RS05570 f398107d1018a04fb51bfbf13d224d0e 128 SMART SM00535 3 127 0.0029 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR44_RS05570 f398107d1018a04fb51bfbf13d224d0e 128 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 1 126 28.033 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CWR44_RS05570 f398107d1018a04fb51bfbf13d224d0e 128 SUPERFAMILY SSF69065 2 125 6.63E-42 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CWR44_RS05570 f398107d1018a04fb51bfbf13d224d0e 128 PIRSF PIRSF005520 1 128 2.5E-51 T 28-03-2018 IPR008226 Mini-ribonuclease 3 family CWR44_RS06290 1466934d882697510138d4b86708a179 193 SMART SM01120 30 189 5.8E-50 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWR44_RS06290 1466934d882697510138d4b86708a179 193 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 7 188 1.7E-65 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 CWR44_RS06290 1466934d882697510138d4b86708a179 193 Pfam PF02734 DAK2 domain 30 187 2.7E-40 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWR44_RS06290 1466934d882697510138d4b86708a179 193 SUPERFAMILY SSF101473 2 188 2.75E-47 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWR44_RS11995 f14af2fd628dce8bf2a0781927c42831 199 Gene3D G3DSA:3.40.50.1360 2 129 4.7E-5 T 28-03-2018 CWR44_RS11995 f14af2fd628dce8bf2a0781927c42831 199 SUPERFAMILY SSF100950 3 195 8.65E-24 T 28-03-2018 CWR44_RS11995 f14af2fd628dce8bf2a0781927c42831 199 Gene3D G3DSA:3.40.50.1360 130 193 4.1E-10 T 28-03-2018 CWR44_RS10675 742d74cc3402ddfadc8b3231e72f3cae 178 SUPERFAMILY SSF100950 1 174 1.03E-43 T 28-03-2018 CWR44_RS10675 742d74cc3402ddfadc8b3231e72f3cae 178 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 174 3.7E-47 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CWR44_RS10675 742d74cc3402ddfadc8b3231e72f3cae 178 PIRSF PIRSF006806 1 177 1.3E-43 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CWR44_RS10675 742d74cc3402ddfadc8b3231e72f3cae 178 Gene3D G3DSA:3.40.50.10420 1 177 4.9E-43 T 28-03-2018 CWR44_RS10675 742d74cc3402ddfadc8b3231e72f3cae 178 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 174 1.3E-38 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CWR44_RS05390 3166cb2d81b2a97e362a04788e2deacf 294 Gene3D G3DSA:3.90.1280.10 236 289 8.2E-22 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CWR44_RS05390 3166cb2d81b2a97e362a04788e2deacf 294 SUPERFAMILY SSF64397 3 241 1.96E-74 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CWR44_RS05390 3166cb2d81b2a97e362a04788e2deacf 294 Gene3D G3DSA:3.55.30.10 3 235 1.4E-75 T 28-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CWR44_RS05390 3166cb2d81b2a97e362a04788e2deacf 294 PIRSF PIRSF005261 1 292 4.0E-75 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CWR44_RS05390 3166cb2d81b2a97e362a04788e2deacf 294 Pfam PF01430 Hsp33 protein 4 280 6.4E-88 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CWR44_RS05390 3166cb2d81b2a97e362a04788e2deacf 294 Hamap MF_00117 33 kDa chaperonin [hslO]. 3 292 39.76 T 28-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CWR44_RS05390 3166cb2d81b2a97e362a04788e2deacf 294 SUPERFAMILY SSF118352 234 291 2.22E-19 T 28-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CWR44_RS01180 d7fed89557e07294ae7e26b513f72030 230 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 4 226 30.274 T 28-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR44_RS01180 d7fed89557e07294ae7e26b513f72030 230 Gene3D G3DSA:3.40.50.1360 2 142 1.8E-39 T 28-03-2018 CWR44_RS01180 d7fed89557e07294ae7e26b513f72030 230 SUPERFAMILY SSF100950 6 152 1.42E-40 T 28-03-2018 CWR44_RS01180 d7fed89557e07294ae7e26b513f72030 230 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 8 224 8.5E-79 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR44_RS01180 d7fed89557e07294ae7e26b513f72030 230 SUPERFAMILY SSF75445 133 209 5.76E-20 T 28-03-2018 CWR44_RS01180 d7fed89557e07294ae7e26b513f72030 230 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 53 222 7.8E-59 T 28-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CWR44_RS01180 d7fed89557e07294ae7e26b513f72030 230 Gene3D G3DSA:3.30.70.260 143 206 1.3E-18 T 28-03-2018 CWR44_RS07645 e0dda9416d8a71f4900fb2a529aa6957 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 321 1.3E-115 T 28-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CWR44_RS07645 e0dda9416d8a71f4900fb2a529aa6957 329 SUPERFAMILY SSF55681 4 241 8.52E-79 T 28-03-2018 CWR44_RS07645 e0dda9416d8a71f4900fb2a529aa6957 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 243 326 2.9E-26 T 28-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CWR44_RS07645 e0dda9416d8a71f4900fb2a529aa6957 329 SUPERFAMILY SSF82649 242 327 3.03E-24 T 28-03-2018 CWR44_RS07645 e0dda9416d8a71f4900fb2a529aa6957 329 Gene3D G3DSA:3.30.390.50 247 329 1.6E-23 T 28-03-2018 CWR44_RS07645 e0dda9416d8a71f4900fb2a529aa6957 329 Gene3D G3DSA:3.30.930.10 2 246 4.5E-71 T 28-03-2018 CWR44_RS07645 e0dda9416d8a71f4900fb2a529aa6957 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 47 153 3.3E-8 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWR44_RS10315 bdc2db5d05d2c2730190cc2f9b682178 239 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 2 233 37.66 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CWR44_RS10315 bdc2db5d05d2c2730190cc2f9b682178 239 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 22 37 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CWR44_RS10315 bdc2db5d05d2c2730190cc2f9b682178 239 Gene3D G3DSA:3.40.50.150 1 235 3.7E-46 T 28-03-2018 CWR44_RS10315 bdc2db5d05d2c2730190cc2f9b682178 239 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 11 233 7.1E-89 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CWR44_RS10315 bdc2db5d05d2c2730190cc2f9b682178 239 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CWR44_RS10315 bdc2db5d05d2c2730190cc2f9b682178 239 SUPERFAMILY SSF53335 5 231 5.11E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS10315 bdc2db5d05d2c2730190cc2f9b682178 239 Pfam PF01209 ubiE/COQ5 methyltransferase family 5 233 1.1E-96 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 SUPERFAMILY SSF52467 185 355 1.92E-32 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 SUPERFAMILY SSF52518 363 543 2.53E-59 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 173 2.3E-50 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 Gene3D G3DSA:3.40.50.970 349 549 2.1E-40 T 28-03-2018 CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 327 1.4E-23 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 SUPERFAMILY SSF52518 5 174 9.32E-48 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 8 545 2.9E-277 T 28-03-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 Gene3D G3DSA:3.40.50.970 1 188 8.6E-48 T 28-03-2018 CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 534 2.6E-43 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 425 444 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CWR44_RS02415 0a983eff8a10107f14bab8e7677e59fd 554 Gene3D G3DSA:3.40.50.1220 189 348 1.3E-24 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS11265 473ecc72003b91c56a9a0788dc46acf1 66 Pfam PF01632 Ribosomal protein L35 2 62 3.6E-24 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11265 473ecc72003b91c56a9a0788dc46acf1 66 SUPERFAMILY SSF143034 2 64 1.28E-21 T 28-03-2018 CWR44_RS11265 473ecc72003b91c56a9a0788dc46acf1 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 28-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS11265 473ecc72003b91c56a9a0788dc46acf1 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.2E-20 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWR44_RS11265 473ecc72003b91c56a9a0788dc46acf1 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.2E-20 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWR44_RS11265 473ecc72003b91c56a9a0788dc46acf1 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.2E-20 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWR44_RS11265 473ecc72003b91c56a9a0788dc46acf1 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 6.3E-25 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWR44_RS11265 473ecc72003b91c56a9a0788dc46acf1 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.916 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CWR44_RS02045 8d5ecb933fb323c45b371b52bc98fd41 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CWR44_RS02045 8d5ecb933fb323c45b371b52bc98fd41 330 SUPERFAMILY SSF51735 103 299 8.47E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02045 8d5ecb933fb323c45b371b52bc98fd41 330 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CWR44_RS02045 8d5ecb933fb323c45b371b52bc98fd41 330 Gene3D G3DSA:3.40.50.720 1 114 1.2E-19 T 28-03-2018 CWR44_RS02045 8d5ecb933fb323c45b371b52bc98fd41 330 Gene3D G3DSA:3.40.50.720 115 301 8.4E-48 T 28-03-2018 CWR44_RS02045 8d5ecb933fb323c45b371b52bc98fd41 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 298 1.8E-51 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWR44_RS02045 8d5ecb933fb323c45b371b52bc98fd41 330 SUPERFAMILY SSF52283 1 136 1.38E-36 T 28-03-2018 CWR44_RS02045 8d5ecb933fb323c45b371b52bc98fd41 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 330 2.5E-24 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CWR44_RS02045 8d5ecb933fb323c45b371b52bc98fd41 330 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CWR44_RS11890 7a7ff023a97581b2f5103eaa9dde02a9 307 TIGRFAM TIGR00109 hemH: ferrochelatase 3 304 1.1E-79 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CWR44_RS11890 7a7ff023a97581b2f5103eaa9dde02a9 307 Hamap MF_00323 Ferrochelatase [hemH]. 3 307 31.021 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CWR44_RS11890 7a7ff023a97581b2f5103eaa9dde02a9 307 ProSitePatterns PS00534 Ferrochelatase signature. 176 195 - T 28-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CWR44_RS11890 7a7ff023a97581b2f5103eaa9dde02a9 307 Pfam PF00762 Ferrochelatase 5 304 4.9E-77 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CWR44_RS11890 7a7ff023a97581b2f5103eaa9dde02a9 307 Gene3D G3DSA:3.40.50.1400 1 155 1.5E-25 T 28-03-2018 CWR44_RS11890 7a7ff023a97581b2f5103eaa9dde02a9 307 Gene3D G3DSA:3.40.50.1400 156 288 8.8E-35 T 28-03-2018 CWR44_RS11890 7a7ff023a97581b2f5103eaa9dde02a9 307 SUPERFAMILY SSF53800 3 305 3.76E-83 T 28-03-2018 CWR44_RS02600 90eebabeac3e092fddb570ec145dd4a8 392 SUPERFAMILY SSF52374 176 387 1.99E-86 T 28-03-2018 CWR44_RS02600 90eebabeac3e092fddb570ec145dd4a8 392 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 14 387 4.9E-144 T 28-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CWR44_RS02600 90eebabeac3e092fddb570ec145dd4a8 392 Pfam PF14306 PUA-like domain 12 170 9.1E-59 T 28-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CWR44_RS02600 90eebabeac3e092fddb570ec145dd4a8 392 Gene3D G3DSA:3.10.400.10 11 185 2.1E-69 T 28-03-2018 CWR44_RS02600 90eebabeac3e092fddb570ec145dd4a8 392 Gene3D G3DSA:3.40.50.620 186 392 1.1E-92 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS02600 90eebabeac3e092fddb570ec145dd4a8 392 SUPERFAMILY SSF88697 12 176 1.29E-56 T 28-03-2018 IPR015947 PUA-like domain CWR44_RS02600 90eebabeac3e092fddb570ec145dd4a8 392 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 35 391 50.345 T 28-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CWR44_RS02600 90eebabeac3e092fddb570ec145dd4a8 392 Pfam PF01747 ATP-sulfurylase 178 387 3.8E-95 T 28-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CWR44_RS09880 7ba37b78a804447e982e82cbae79c5c3 403 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 382 1.5E-41 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR44_RS09880 7ba37b78a804447e982e82cbae79c5c3 403 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 12 394 8.4E-195 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWR44_RS09880 7ba37b78a804447e982e82cbae79c5c3 403 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 7 395 50.731 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWR44_RS09880 7ba37b78a804447e982e82cbae79c5c3 403 Gene3D G3DSA:3.40.50.1100 14 202 3.1E-42 T 28-03-2018 CWR44_RS09880 7ba37b78a804447e982e82cbae79c5c3 403 SUPERFAMILY SSF53686 10 393 5.76E-139 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR44_RS09880 7ba37b78a804447e982e82cbae79c5c3 403 PIRSF PIRSF001413 1 401 1.1E-161 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWR44_RS09880 7ba37b78a804447e982e82cbae79c5c3 403 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 86 100 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CWR44_RS09880 7ba37b78a804447e982e82cbae79c5c3 403 Gene3D G3DSA:3.40.50.1100 203 403 9.5E-38 T 28-03-2018 CWR44_RS08400 053eb8a689fb2e3d30e9204a6db5d51d 175 Gene3D G3DSA:3.40.50.2020 1 175 1.8E-30 T 28-03-2018 CWR44_RS08400 053eb8a689fb2e3d30e9204a6db5d51d 175 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 3 175 32.973 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CWR44_RS08400 053eb8a689fb2e3d30e9204a6db5d51d 175 SUPERFAMILY SSF53271 4 169 2.23E-37 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWR44_RS08400 053eb8a689fb2e3d30e9204a6db5d51d 175 Pfam PF00156 Phosphoribosyl transferase domain 7 159 1.2E-17 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR44_RS02205 6b2dfe7e26bfa53625a2878973f6c3de 388 SUPERFAMILY SSF53901 3 166 1.61E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS02205 6b2dfe7e26bfa53625a2878973f6c3de 388 SUPERFAMILY SSF53901 169 386 2.01E-69 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS02205 6b2dfe7e26bfa53625a2878973f6c3de 388 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 3 165 1.5E-20 T 28-03-2018 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: R-HSA-1989781 CWR44_RS02205 6b2dfe7e26bfa53625a2878973f6c3de 388 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 258 383 6.3E-16 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CWR44_RS02205 6b2dfe7e26bfa53625a2878973f6c3de 388 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 177 251 1.2E-10 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CWR44_RS02205 6b2dfe7e26bfa53625a2878973f6c3de 388 Gene3D G3DSA:3.40.47.10 175 319 1.9E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS02205 6b2dfe7e26bfa53625a2878973f6c3de 388 Gene3D G3DSA:3.40.47.10 6 173 8.8E-12 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS02205 6b2dfe7e26bfa53625a2878973f6c3de 388 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 384 4.8E-158 T 28-03-2018 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922 CWR44_RS02595 1981aa587b3a2d91202852e4c2b9ca9e 199 Pfam PF01583 Adenylylsulphate kinase 26 181 1.4E-74 T 28-03-2018 CWR44_RS02595 1981aa587b3a2d91202852e4c2b9ca9e 199 SUPERFAMILY SSF52540 23 196 1.17E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS02595 1981aa587b3a2d91202852e4c2b9ca9e 199 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 9 193 2.5E-87 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CWR44_RS02595 1981aa587b3a2d91202852e4c2b9ca9e 199 Gene3D G3DSA:3.40.50.300 22 199 1.0E-55 T 28-03-2018 CWR44_RS02595 1981aa587b3a2d91202852e4c2b9ca9e 199 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 25 197 38.801 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CWR44_RS07780 ad58978aeb092f2af6a4cafca4978347 96 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 5 91 7.0E-31 T 28-03-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 CWR44_RS07780 ad58978aeb092f2af6a4cafca4978347 96 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 8 80 2.5E-11 T 28-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CWR44_RS09435 1ffde4866878c2a2818931b8d9509d8d 76 Pfam PF01381 Helix-turn-helix 13 62 7.9E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS09435 1ffde4866878c2a2818931b8d9509d8d 76 Gene3D G3DSA:1.10.260.40 2 73 1.5E-9 T 28-03-2018 CWR44_RS09435 1ffde4866878c2a2818931b8d9509d8d 76 SMART SM00530 9 63 1.5E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS09435 1ffde4866878c2a2818931b8d9509d8d 76 SUPERFAMILY SSF47413 9 64 2.15E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS02125 ee21d14a93342ee40ac0020aa077dedf 100 SUPERFAMILY SSF103481 17 96 7.06E-12 T 28-03-2018 CWR44_RS02125 ee21d14a93342ee40ac0020aa077dedf 100 Pfam PF00892 EamA-like transporter family 21 92 3.7E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR44_RS00215 09e9ed9d328964316f7634c74172e7a6 278 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 6 275 1.5E-60 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CWR44_RS00215 09e9ed9d328964316f7634c74172e7a6 278 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 274 3.1E-78 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CWR44_RS00215 09e9ed9d328964316f7634c74172e7a6 278 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 181 187 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWR44_RS00215 09e9ed9d328964316f7634c74172e7a6 278 Gene3D G3DSA:1.10.8.10 2 80 3.4E-14 T 28-03-2018 CWR44_RS00215 09e9ed9d328964316f7634c74172e7a6 278 Pfam PF05175 Methyltransferase small domain 98 192 2.0E-13 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CWR44_RS00215 09e9ed9d328964316f7634c74172e7a6 278 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 12 278 37.646 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CWR44_RS00215 09e9ed9d328964316f7634c74172e7a6 278 Gene3D G3DSA:3.40.50.150 81 278 5.5E-35 T 28-03-2018 CWR44_RS00215 09e9ed9d328964316f7634c74172e7a6 278 SUPERFAMILY SSF53335 5 276 6.87E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS03750 c587c9bd8865b5331fc71b46e9c63452 207 Gene3D G3DSA:3.40.109.10 2 207 2.7E-41 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR44_RS03750 c587c9bd8865b5331fc71b46e9c63452 207 Pfam PF00881 Nitroreductase family 10 187 3.1E-26 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR44_RS03750 c587c9bd8865b5331fc71b46e9c63452 207 SUPERFAMILY SSF55469 4 204 7.98E-56 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR44_RS05400 d7d4009310bf353454174d9c5eee031d 267 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 40 53 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR44_RS05400 d7d4009310bf353454174d9c5eee031d 267 SUPERFAMILY SSF51717 4 256 2.75E-86 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR44_RS05400 d7d4009310bf353454174d9c5eee031d 267 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 6 21 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR44_RS05400 d7d4009310bf353454174d9c5eee031d 267 Pfam PF00809 Pterin binding enzyme 7 241 5.4E-82 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CWR44_RS05400 d7d4009310bf353454174d9c5eee031d 267 Gene3D G3DSA:3.20.20.20 1 266 1.5E-96 T 28-03-2018 CWR44_RS05400 d7d4009310bf353454174d9c5eee031d 267 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 5 254 2.2E-92 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CWR44_RS08445 60c78b533c4fdab6fcba917a3fc2bc11 134 Gene3D G3DSA:3.10.180.10 1 134 1.1E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS08445 60c78b533c4fdab6fcba917a3fc2bc11 134 SUPERFAMILY SSF54593 4 131 2.22E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS08445 60c78b533c4fdab6fcba917a3fc2bc11 134 PIRSF PIRSF021700 1 133 2.2E-39 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CWR44_RS08445 60c78b533c4fdab6fcba917a3fc2bc11 134 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 129 7.7E-38 T 28-03-2018 IPR028973 PhnB-like CWR44_RS10430 ad2ae03ae388066059e527b4e391024a 302 Pfam PF00248 Aldo/keto reductase family 14 289 5.0E-55 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS10430 ad2ae03ae388066059e527b4e391024a 302 Gene3D G3DSA:3.20.20.100 1 302 1.9E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS10430 ad2ae03ae388066059e527b4e391024a 302 SUPERFAMILY SSF51430 1 294 2.23E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS07745 2e270e5b58bb91f0456b379bc0f43d6f 139 Gene3D G3DSA:1.10.10.10 1 136 1.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS07745 2e270e5b58bb91f0456b379bc0f43d6f 139 SUPERFAMILY SSF46785 3 135 6.07E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS07745 2e270e5b58bb91f0456b379bc0f43d6f 139 SMART SM00347 22 122 4.2E-28 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS07745 2e270e5b58bb91f0456b379bc0f43d6f 139 Pfam PF01047 MarR family 29 87 7.9E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS07745 2e270e5b58bb91f0456b379bc0f43d6f 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 1.7E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS07745 2e270e5b58bb91f0456b379bc0f43d6f 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 1.7E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS07745 2e270e5b58bb91f0456b379bc0f43d6f 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 1.7E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS07745 2e270e5b58bb91f0456b379bc0f43d6f 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 78 1.7E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS11740 7dd6058b377137ac06385babfd8ba92a 496 Gene3D G3DSA:3.50.50.60 189 494 1.7E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11740 7dd6058b377137ac06385babfd8ba92a 496 SUPERFAMILY SSF51735 342 355 3.46E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS11740 7dd6058b377137ac06385babfd8ba92a 496 SUPERFAMILY SSF51735 135 219 3.46E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS11740 7dd6058b377137ac06385babfd8ba92a 496 SUPERFAMILY SSF51735 1 56 3.46E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS11740 7dd6058b377137ac06385babfd8ba92a 496 Gene3D G3DSA:3.50.50.60 1 176 1.2E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11740 7dd6058b377137ac06385babfd8ba92a 496 Pfam PF13454 FAD-NAD(P)-binding 4 158 6.7E-28 T 28-03-2018 CWR44_RS11740 7dd6058b377137ac06385babfd8ba92a 496 SUPERFAMILY SSF51905 1 47 4.14E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11740 7dd6058b377137ac06385babfd8ba92a 496 SUPERFAMILY SSF51905 339 481 4.14E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11740 7dd6058b377137ac06385babfd8ba92a 496 SUPERFAMILY SSF51905 78 232 4.14E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04045 25bc125c033ca9267a3f9d33c4e82104 185 Pfam PF02669 K+-transporting ATPase, c chain 5 184 5.4E-62 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CWR44_RS04045 25bc125c033ca9267a3f9d33c4e82104 185 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 1 185 29.645 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CWR44_RS04045 25bc125c033ca9267a3f9d33c4e82104 185 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 4 185 2.4E-52 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CWR44_RS04045 25bc125c033ca9267a3f9d33c4e82104 185 PIRSF PIRSF001296 1 185 4.4E-67 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 ProSitePatterns PS01014 Transcription termination factor nusG signature. 165 174 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 Pfam PF02357 Transcription termination factor nusG 8 114 1.9E-27 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 SMART SM00738 7 118 4.3E-49 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 PRINTS PR00338 Transcription termination factor NUSG signature 140 155 2.0E-18 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 PRINTS PR00338 Transcription termination factor NUSG signature 62 74 2.0E-18 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 PRINTS PR00338 Transcription termination factor NUSG signature 158 174 2.0E-18 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 Gene3D G3DSA:3.30.70.940 7 121 1.3E-42 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 Pfam PF00467 KOW motif 131 164 3.0E-7 T 28-03-2018 IPR005824 KOW CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 10 182 5.1E-60 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 SUPERFAMILY SSF82679 8 119 7.98E-39 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 Gene3D G3DSA:2.30.30.30 123 182 9.9E-20 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 SMART SM00739 128 155 5.2E-5 T 28-03-2018 IPR005824 KOW CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 7 182 26.98 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CWR44_RS05600 f2cc6dff06bf7c92dd55d1bb08dbb245 182 SUPERFAMILY SSF50104 126 182 1.29E-18 T 28-03-2018 IPR008991 Translation protein SH3-like domain CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 Hamap MF_01685 Ferredoxin--NADP reductase. 1 328 34.709 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 Gene3D G3DSA:3.50.50.60 257 342 1.3E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 Gene3D G3DSA:3.50.50.60 130 243 2.5E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 3.4E-29 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 3.4E-29 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 3.4E-29 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 3.4E-29 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 197 213 3.4E-29 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 300 4.1E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 3.8E-15 T 28-03-2018 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.8E-15 T 28-03-2018 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 3.8E-15 T 28-03-2018 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 SUPERFAMILY SSF51905 1 314 1.18E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01385 a0520001a2bc468425f520c62e313ab5 343 Gene3D G3DSA:3.50.50.60 1 129 1.7E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07025 5bf994982bc35080c8114dead8893275 193 SUPERFAMILY SSF54001 44 177 7.85E-10 T 28-03-2018 CWR44_RS07025 5bf994982bc35080c8114dead8893275 193 Gene3D G3DSA:3.90.1720.10 41 192 5.6E-9 T 28-03-2018 CWR44_RS11645 f57ca020cb831a21f7f4e132e7fa7c9a 230 Pfam PF00849 RNA pseudouridylate synthase 62 190 4.4E-17 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS11645 f57ca020cb831a21f7f4e132e7fa7c9a 230 SMART SM00363 1 63 4.2E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS11645 f57ca020cb831a21f7f4e132e7fa7c9a 230 Gene3D G3DSA:3.10.290.10 1 72 5.2E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS11645 f57ca020cb831a21f7f4e132e7fa7c9a 230 SUPERFAMILY SSF55174 1 58 6.48E-13 T 28-03-2018 CWR44_RS11645 f57ca020cb831a21f7f4e132e7fa7c9a 230 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWR44_RS11645 f57ca020cb831a21f7f4e132e7fa7c9a 230 Pfam PF01479 S4 domain 1 45 7.9E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS11645 f57ca020cb831a21f7f4e132e7fa7c9a 230 SUPERFAMILY SSF55120 61 225 1.01E-42 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS11645 f57ca020cb831a21f7f4e132e7fa7c9a 230 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 221 3.6E-45 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CWR44_RS11645 f57ca020cb831a21f7f4e132e7fa7c9a 230 Gene3D G3DSA:3.30.2350.10 73 226 3.4E-39 T 28-03-2018 CWR44_RS05645 df9d581b062508f035c8b3ce01b2902c 86 SUPERFAMILY SSF55315 11 84 1.18E-16 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWR44_RS05645 df9d581b062508f035c8b3ce01b2902c 86 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 10 84 7.5E-12 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CWR44_RS05645 df9d581b062508f035c8b3ce01b2902c 86 Gene3D G3DSA:3.30.1330.30 4 86 1.0E-14 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWR44_RS07530 1cc65df84fd33560b0e42586e6466512 121 Gene3D G3DSA:1.10.490.10 1 121 1.9E-28 T 28-03-2018 CWR44_RS07530 1cc65df84fd33560b0e42586e6466512 121 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 49 73 - T 28-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 CWR44_RS07530 1cc65df84fd33560b0e42586e6466512 121 SUPERFAMILY SSF46458 4 120 3.08E-32 T 28-03-2018 IPR009050 Globin-like CWR44_RS07530 1cc65df84fd33560b0e42586e6466512 121 Pfam PF01152 Bacterial-like globin 6 118 1.0E-26 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 Gene3D G3DSA:3.40.50.970 151 525 7.7E-76 T 28-03-2018 CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 1 934 21.608 T 28-03-2018 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 SMART SM00861 592 788 5.3E-44 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 16 929 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 SUPERFAMILY SSF52518 139 532 2.44E-70 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 Gene3D G3DSA:3.40.50.970 589 801 1.1E-48 T 28-03-2018 CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 Pfam PF02779 Transketolase, pyrimidine binding domain 592 788 4.6E-54 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 795 930 6.0E-32 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 Gene3D G3DSA:1.10.287.1150 71 149 3.7E-8 T 28-03-2018 CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 SUPERFAMILY SSF52518 577 794 8.93E-40 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 PIRSF PIRSF000157 1 934 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CWR44_RS10065 8ca69347ea413dffe317562bfa558f1a 934 Pfam PF00676 Dehydrogenase E1 component 217 525 1.6E-62 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CWR44_RS03275 071ded6ae5fffe04634e9beb85356763 399 Pfam PF05684 Protein of unknown function (DUF819) 18 395 6.1E-95 T 28-03-2018 IPR008537 Protein of unknown function DUF819 CWR44_RS06260 acb149105b421ecc30935c32d90c13f3 410 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 193 408 8.0E-48 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CWR44_RS06260 acb149105b421ecc30935c32d90c13f3 410 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 6.0E-17 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CWR44_RS07700 bdaaf6535bda2ded056c2b35289b48c3 312 Pfam PF01040 UbiA prenyltransferase family 27 276 2.0E-34 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CWR44_RS07700 bdaaf6535bda2ded056c2b35289b48c3 312 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 10 303 18.96 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CWR44_RS07700 bdaaf6535bda2ded056c2b35289b48c3 312 PIRSF PIRSF005355 2 308 5.3E-76 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CWR44_RS00080 e14f581890d1d092886bca615ccce33c 438 Pfam PF01610 Transposase 164 417 8.6E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS00080 e14f581890d1d092886bca615ccce33c 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 4.3E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS08020 136d5ba59b779d1f380b150c949475d4 267 SUPERFAMILY SSF161098 2 257 4.67E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS08020 136d5ba59b779d1f380b150c949475d4 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 258 1.1E-8 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS08020 136d5ba59b779d1f380b150c949475d4 267 Gene3D G3DSA:1.10.3720.10 6 260 1.7E-32 T 28-03-2018 CWR44_RS06060 d8547e66066e30ae53312bceb4c4fc2f 215 SMART SM00478 37 194 5.5E-18 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWR44_RS06060 d8547e66066e30ae53312bceb4c4fc2f 215 Gene3D G3DSA:1.10.340.30 20 124 1.5E-21 T 28-03-2018 CWR44_RS06060 d8547e66066e30ae53312bceb4c4fc2f 215 Gene3D G3DSA:1.10.1670.10 125 203 1.7E-8 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CWR44_RS06060 d8547e66066e30ae53312bceb4c4fc2f 215 PIRSF PIRSF001435 3 201 1.6E-50 T 28-03-2018 CWR44_RS06060 d8547e66066e30ae53312bceb4c4fc2f 215 SUPERFAMILY SSF48150 6 197 2.36E-42 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CWR44_RS06060 d8547e66066e30ae53312bceb4c4fc2f 215 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 170 9.6E-13 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CWR44_RS06335 dfdb37271ce772aac00603f843908530 253 SMART SM00382 32 219 1.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS06335 dfdb37271ce772aac00603f843908530 253 Pfam PF00005 ABC transporter 23 171 1.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06335 dfdb37271ce772aac00603f843908530 253 Gene3D G3DSA:3.40.50.300 1 244 3.5E-60 T 28-03-2018 CWR44_RS06335 dfdb37271ce772aac00603f843908530 253 SUPERFAMILY SSF52540 3 224 3.41E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07090 01557f11be115c93a8f2462283c93eab 117 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 116 5.3E-43 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CWR44_RS07090 01557f11be115c93a8f2462283c93eab 117 SUPERFAMILY SSF52833 1 116 2.44E-33 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS07090 01557f11be115c93a8f2462283c93eab 117 Gene3D G3DSA:3.40.30.10 1 116 4.3E-34 T 28-03-2018 CWR44_RS07090 01557f11be115c93a8f2462283c93eab 117 Pfam PF03960 ArsC family 9 115 3.6E-14 T 28-03-2018 IPR006660 Arsenate reductase-like CWR44_RS07835 9bb5389db168c71bc1c5b2efee48209f 234 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 232 31.507 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS07835 9bb5389db168c71bc1c5b2efee48209f 234 Gene3D G3DSA:3.30.470.20 91 218 1.9E-47 T 28-03-2018 CWR44_RS07835 9bb5389db168c71bc1c5b2efee48209f 234 Gene3D G3DSA:3.30.200.20 1 90 1.2E-27 T 28-03-2018 CWR44_RS07835 9bb5389db168c71bc1c5b2efee48209f 234 ProSitePatterns PS01057 SAICAR synthetase signature 1. 83 97 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS07835 9bb5389db168c71bc1c5b2efee48209f 234 SUPERFAMILY SSF56104 2 230 7.85E-76 T 28-03-2018 CWR44_RS07835 9bb5389db168c71bc1c5b2efee48209f 234 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 4 212 1.5E-69 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CWR44_RS07835 9bb5389db168c71bc1c5b2efee48209f 234 Pfam PF01259 SAICAR synthetase 4 225 3.3E-61 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS00200 05297fff9f134625648e86ae3ea78a98 174 SUPERFAMILY SSF110710 2 174 1.52E-72 T 28-03-2018 CWR44_RS00200 05297fff9f134625648e86ae3ea78a98 174 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 2 173 3.6E-85 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWR44_RS00200 05297fff9f134625648e86ae3ea78a98 174 PIRSF PIRSF007510 1 174 2.2E-82 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWR44_RS00200 05297fff9f134625648e86ae3ea78a98 174 Hamap MF_00800 UPF0340 protein . 1 174 88.162 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWR44_RS00200 05297fff9f134625648e86ae3ea78a98 174 Pfam PF04260 Protein of unknown function (DUF436) 4 173 2.8E-72 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWR44_RS00200 05297fff9f134625648e86ae3ea78a98 174 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 24 173 4.0E-83 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWR44_RS00200 05297fff9f134625648e86ae3ea78a98 174 Gene3D G3DSA:3.40.50.10360 1 174 2.2E-74 T 28-03-2018 IPR006340 Protein of unknown function DUF436 CWR44_RS09375 7a0f8647d9d502138bc81d8f99fa35f8 89 Gene3D G3DSA:4.10.830.10 1 89 9.8E-36 T 28-03-2018 CWR44_RS09375 7a0f8647d9d502138bc81d8f99fa35f8 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 25.13 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CWR44_RS09375 7a0f8647d9d502138bc81d8f99fa35f8 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 5.1E-28 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS09375 7a0f8647d9d502138bc81d8f99fa35f8 89 SUPERFAMILY SSF57716 2 89 9.98E-32 T 28-03-2018 CWR44_RS09375 7a0f8647d9d502138bc81d8f99fa35f8 89 ProSitePatterns PS00527 Ribosomal protein S14 signature. 50 73 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS03645 cfbceb7d0e6734d06406cd48cd2472c7 283 Gene3D G3DSA:1.10.10.10 3 78 6.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03645 cfbceb7d0e6734d06406cd48cd2472c7 283 Pfam PF01380 SIS domain 128 255 2.2E-23 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR44_RS03645 cfbceb7d0e6734d06406cd48cd2472c7 283 SUPERFAMILY SSF53697 96 280 4.73E-38 T 28-03-2018 CWR44_RS03645 cfbceb7d0e6734d06406cd48cd2472c7 283 Gene3D G3DSA:3.40.50.10490 79 283 2.1E-34 T 28-03-2018 CWR44_RS03645 cfbceb7d0e6734d06406cd48cd2472c7 283 Pfam PF01418 Helix-turn-helix domain, rpiR family 5 76 2.1E-22 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR44_RS03645 cfbceb7d0e6734d06406cd48cd2472c7 283 SUPERFAMILY SSF46689 5 77 4.84E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS05010 8f61fa40c6ff8dbe91e393f340a759f0 128 Gene3D G3DSA:1.10.1270.10 13 124 2.6E-5 T 28-03-2018 CWR44_RS05010 8f61fa40c6ff8dbe91e393f340a759f0 128 SUPERFAMILY SSF88659 44 108 2.27E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 6 191 8.6E-48 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 Gene3D G3DSA:3.40.50.300 1 207 8.1E-64 T 28-03-2018 CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 TIGRFAM TIGR00235 udk: uridine kinase 4 204 6.3E-90 T 28-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 SUPERFAMILY SSF52540 5 196 7.34E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 PRINTS PR00988 Uridine kinase signature 4 21 8.0E-38 T 28-03-2018 CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 PRINTS PR00988 Uridine kinase signature 171 184 8.0E-38 T 28-03-2018 CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 PRINTS PR00988 Uridine kinase signature 34 45 8.0E-38 T 28-03-2018 CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 PRINTS PR00988 Uridine kinase signature 79 94 8.0E-38 T 28-03-2018 CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 PRINTS PR00988 Uridine kinase signature 149 160 8.0E-38 T 28-03-2018 CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 PRINTS PR00988 Uridine kinase signature 135 145 8.0E-38 T 28-03-2018 CWR44_RS10955 0d27ac0c706ee64dbb0471bef737daa9 207 Hamap MF_00551 Uridine kinase [udk]. 1 205 41.223 T 28-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 CWR44_RS03830 ee07ca009485ae27d7f393363e877e57 255 SUPERFAMILY SSF52540 10 246 3.18E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03830 ee07ca009485ae27d7f393363e877e57 255 SMART SM00382 39 222 4.8E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03830 ee07ca009485ae27d7f393363e877e57 255 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS03830 ee07ca009485ae27d7f393363e877e57 255 Gene3D G3DSA:3.40.50.300 11 254 1.0E-52 T 28-03-2018 CWR44_RS03830 ee07ca009485ae27d7f393363e877e57 255 Pfam PF00005 ABC transporter 30 173 3.2E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS08590 28949ed1367d3657c41163d15e6b284a 110 SUPERFAMILY SSF88659 5 107 2.24E-32 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS08590 28949ed1367d3657c41163d15e6b284a 110 Hamap MF_00245 UPF0122 protein . 6 106 22.174 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CWR44_RS08590 28949ed1367d3657c41163d15e6b284a 110 Gene3D G3DSA:1.10.10.10 1 110 6.5E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS08590 28949ed1367d3657c41163d15e6b284a 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 7 104 1.2E-40 T 28-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CWR44_RS06650 049851025ad6fcadb465420732d52ae1 351 Gene3D G3DSA:3.90.1150.10 249 350 5.1E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS06650 049851025ad6fcadb465420732d52ae1 351 SUPERFAMILY SSF53383 28 349 3.54E-76 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS06650 049851025ad6fcadb465420732d52ae1 351 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 350 55.866 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CWR44_RS06650 049851025ad6fcadb465420732d52ae1 351 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 218 227 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CWR44_RS06650 049851025ad6fcadb465420732d52ae1 351 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 2 348 8.0E-93 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CWR44_RS06650 049851025ad6fcadb465420732d52ae1 351 Gene3D G3DSA:3.40.640.10 43 248 8.7E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS06650 049851025ad6fcadb465420732d52ae1 351 Pfam PF00155 Aminotransferase class I and II 31 345 2.6E-51 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR44_RS04435 f2000d66977bc0595a25f9b985867431 77 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 5 62 2.4E-27 T 28-03-2018 IPR014330 RNA-binding S4-related,YaaA CWR44_RS04435 f2000d66977bc0595a25f9b985867431 77 SUPERFAMILY SSF55174 7 62 9.81E-16 T 28-03-2018 CWR44_RS04435 f2000d66977bc0595a25f9b985867431 77 Gene3D G3DSA:3.10.290.10 2 66 8.2E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS04435 f2000d66977bc0595a25f9b985867431 77 Pfam PF13275 S4 domain 11 62 6.0E-23 T 28-03-2018 CWR44_RS00125 050f0b4423e9705c3fe672966849d273 145 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 5 144 31.972 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWR44_RS00125 050f0b4423e9705c3fe672966849d273 145 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 6 142 6.9E-53 T 28-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWR44_RS00125 050f0b4423e9705c3fe672966849d273 145 Gene3D G3DSA:3.10.129.10 1 145 6.0E-54 T 28-03-2018 CWR44_RS00125 050f0b4423e9705c3fe672966849d273 145 SUPERFAMILY SSF54637 3 142 1.06E-46 T 28-03-2018 IPR029069 HotDog domain CWR44_RS00125 050f0b4423e9705c3fe672966849d273 145 Pfam PF07977 FabA-like domain 14 135 7.0E-34 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CWR44_RS02685 c26025ba8d2db639fdc99a877875c4ea 379 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 364 1.5E-158 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CWR44_RS02685 c26025ba8d2db639fdc99a877875c4ea 379 Gene3D G3DSA:3.40.50.2000 203 348 2.3E-37 T 28-03-2018 CWR44_RS02685 c26025ba8d2db639fdc99a877875c4ea 379 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 361 2.8E-120 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CWR44_RS02685 c26025ba8d2db639fdc99a877875c4ea 379 Gene3D G3DSA:3.40.50.2000 2 202 2.2E-79 T 28-03-2018 CWR44_RS02685 c26025ba8d2db639fdc99a877875c4ea 379 SUPERFAMILY SSF53756 1 368 5.81E-137 T 28-03-2018 CWR44_RS11745 b3a233d01e107332133487a5f0288065 438 Pfam PF01610 Transposase 164 417 3.6E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS11745 b3a233d01e107332133487a5f0288065 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 4.3E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS10805 396def04900c9e98f5ec9a2411df4342 448 Pfam PF04055 Radical SAM superfamily 149 318 3.1E-30 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS10805 396def04900c9e98f5ec9a2411df4342 448 Gene3D G3DSA:3.80.30.20 140 374 8.2E-51 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CWR44_RS10805 396def04900c9e98f5ec9a2411df4342 448 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 1.0E-25 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CWR44_RS10805 396def04900c9e98f5ec9a2411df4342 448 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CWR44_RS10805 396def04900c9e98f5ec9a2411df4342 448 SMART SM00729 143 360 1.7E-58 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR44_RS10805 396def04900c9e98f5ec9a2411df4342 448 SUPERFAMILY SSF102114 125 362 7.32E-58 T 28-03-2018 CWR44_RS10805 396def04900c9e98f5ec9a2411df4342 448 Pfam PF01938 TRAM domain 376 422 1.5E-4 T 28-03-2018 IPR002792 TRAM domain CWR44_RS10805 396def04900c9e98f5ec9a2411df4342 448 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 419 1.8E-144 T 28-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 CWR44_RS10805 396def04900c9e98f5ec9a2411df4342 448 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 424 4.4E-149 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CWR44_RS10805 396def04900c9e98f5ec9a2411df4342 448 Gene3D G3DSA:3.40.50.2300 8 131 0.005 T 28-03-2018 CWR44_RS10215 d86d87102fe58e8d26a520fde7adba77 208 SUPERFAMILY SSF52980 34 200 5.09E-65 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWR44_RS10215 d86d87102fe58e8d26a520fde7adba77 208 TIGRFAM TIGR00648 recU: recombination protein U 31 199 3.7E-84 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CWR44_RS10215 d86d87102fe58e8d26a520fde7adba77 208 Pfam PF03838 Recombination protein U 32 197 2.0E-64 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CWR44_RS10215 d86d87102fe58e8d26a520fde7adba77 208 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 208 101.492 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CWR44_RS10215 d86d87102fe58e8d26a520fde7adba77 208 Gene3D G3DSA:3.40.1350.10 33 199 6.0E-62 T 28-03-2018 CWR44_RS10215 d86d87102fe58e8d26a520fde7adba77 208 PIRSF PIRSF037785 23 207 1.2E-80 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CWR44_RS01635 51a65cc3bb1e693ef85b0a40a58d1547 399 Gene3D G3DSA:1.20.1250.20 4 199 8.6E-28 T 28-03-2018 CWR44_RS01635 51a65cc3bb1e693ef85b0a40a58d1547 399 SUPERFAMILY SSF103473 6 397 3.01E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01635 51a65cc3bb1e693ef85b0a40a58d1547 399 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 13 386 3.2E-66 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CWR44_RS01635 51a65cc3bb1e693ef85b0a40a58d1547 399 Pfam PF07690 Major Facilitator Superfamily 20 360 7.6E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS01635 51a65cc3bb1e693ef85b0a40a58d1547 399 Gene3D G3DSA:1.20.1250.20 200 398 3.1E-17 T 28-03-2018 CWR44_RS08295 c2175802365e58ef18acbb16029c3eb9 143 SUPERFAMILY SSF89447 1 136 8.97E-54 T 28-03-2018 CWR44_RS08295 c2175802365e58ef18acbb16029c3eb9 143 Gene3D G3DSA:2.10.260.10 1 58 9.8E-5 T 28-03-2018 CWR44_RS08295 c2175802365e58ef18acbb16029c3eb9 143 Gene3D G3DSA:2.10.260.10 73 124 4.6E-9 T 28-03-2018 CWR44_RS08295 c2175802365e58ef18acbb16029c3eb9 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 141 5.5E-28 T 28-03-2018 IPR020603 MraZ domain CWR44_RS08295 c2175802365e58ef18acbb16029c3eb9 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 5.2E-22 T 28-03-2018 IPR020603 MraZ domain CWR44_RS08295 c2175802365e58ef18acbb16029c3eb9 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 59.264 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CWR44_RS08295 c2175802365e58ef18acbb16029c3eb9 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 136 1.0E-67 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CWR44_RS08295 c2175802365e58ef18acbb16029c3eb9 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 142 1.2E-55 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CWR44_RS10745 2f05f4e83cf8b45d6e9fa02a302668cc 207 Gene3D G3DSA:1.10.10.10 1 60 1.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10745 2f05f4e83cf8b45d6e9fa02a302668cc 207 PIRSF PIRSF026546 1 207 6.1E-98 T 28-03-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS CWR44_RS10745 2f05f4e83cf8b45d6e9fa02a302668cc 207 SUPERFAMILY SSF54631 73 200 5.49E-20 T 28-03-2018 CWR44_RS10745 2f05f4e83cf8b45d6e9fa02a302668cc 207 Pfam PF00571 CBS domain 147 200 0.0022 T 28-03-2018 IPR000644 CBS domain CWR44_RS10745 2f05f4e83cf8b45d6e9fa02a302668cc 207 Pfam PF00571 CBS domain 77 130 2.2E-6 T 28-03-2018 IPR000644 CBS domain CWR44_RS10745 2f05f4e83cf8b45d6e9fa02a302668cc 207 SMART SM00116 150 202 6.3 T 28-03-2018 IPR000644 CBS domain CWR44_RS10745 2f05f4e83cf8b45d6e9fa02a302668cc 207 SMART SM00116 83 131 3.5 T 28-03-2018 IPR000644 CBS domain CWR44_RS10745 2f05f4e83cf8b45d6e9fa02a302668cc 207 SUPERFAMILY SSF46785 2 72 3.03E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10745 2f05f4e83cf8b45d6e9fa02a302668cc 207 Gene3D G3DSA:3.10.580.10 61 205 1.8E-21 T 28-03-2018 CWR44_RS10745 2f05f4e83cf8b45d6e9fa02a302668cc 207 Pfam PF08279 HTH domain 6 57 7.3E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CWR44_RS13135 77579cbf61a277524b3a547d347d0bd4 224 Gene3D G3DSA:3.30.420.10 70 217 2.9E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS13135 77579cbf61a277524b3a547d347d0bd4 224 SUPERFAMILY SSF53098 69 216 1.29E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS13135 77579cbf61a277524b3a547d347d0bd4 224 Gene3D G3DSA:1.10.10.10 5 69 9.6E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS13135 77579cbf61a277524b3a547d347d0bd4 224 Pfam PF13610 DDE domain 72 203 5.2E-39 T 28-03-2018 IPR032874 DDE domain CWR44_RS03500 80a1dff1d5ca89ac522aace94d709709 228 SUPERFAMILY SSF52317 4 225 6.17E-73 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS03500 80a1dff1d5ca89ac522aace94d709709 228 Pfam PF01965 DJ-1/PfpI family 29 225 1.5E-16 T 28-03-2018 IPR002818 DJ-1/PfpI CWR44_RS03500 80a1dff1d5ca89ac522aace94d709709 228 Gene3D G3DSA:3.40.50.880 1 228 3.6E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS09215 f7c8a9847c61c302e37d3e4afa4b7ad8 305 SMART SM00644 23 167 0.0018 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS09215 f7c8a9847c61c302e37d3e4afa4b7ad8 305 SUPERFAMILY SSF55846 30 174 4.03E-21 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS09215 f7c8a9847c61c302e37d3e4afa4b7ad8 305 Gene3D G3DSA:3.40.80.10 20 204 9.8E-25 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS09215 f7c8a9847c61c302e37d3e4afa4b7ad8 305 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 37 167 2.3E-15 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS02180 176770c2ef253e8e1855f59b5e780b8b 294 Gene3D G3DSA:3.40.190.10 177 264 4.5E-16 T 28-03-2018 CWR44_RS02180 176770c2ef253e8e1855f59b5e780b8b 294 Pfam PF03466 LysR substrate binding domain 89 291 1.5E-39 T 28-03-2018 IPR005119 LysR, substrate-binding CWR44_RS02180 176770c2ef253e8e1855f59b5e780b8b 294 SUPERFAMILY SSF53850 90 291 2.26E-35 T 28-03-2018 CWR44_RS02180 176770c2ef253e8e1855f59b5e780b8b 294 Gene3D G3DSA:1.10.10.10 1 83 4.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02180 176770c2ef253e8e1855f59b5e780b8b 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.5E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS02180 176770c2ef253e8e1855f59b5e780b8b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS02180 176770c2ef253e8e1855f59b5e780b8b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS02180 176770c2ef253e8e1855f59b5e780b8b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS02180 176770c2ef253e8e1855f59b5e780b8b 294 Gene3D G3DSA:3.40.190.10 87 176 8.0E-19 T 28-03-2018 CWR44_RS02180 176770c2ef253e8e1855f59b5e780b8b 294 SUPERFAMILY SSF46785 1 82 5.83E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02505 2817025ec5f82f7c59780ddb991c6273 111 SUPERFAMILY SSF53850 2 109 2.35E-14 T 28-03-2018 CWR44_RS02505 2817025ec5f82f7c59780ddb991c6273 111 Gene3D G3DSA:3.40.190.10 1 79 1.6E-11 T 28-03-2018 CWR44_RS02505 2817025ec5f82f7c59780ddb991c6273 111 Pfam PF03466 LysR substrate binding domain 2 105 6.2E-15 T 28-03-2018 IPR005119 LysR, substrate-binding CWR44_RS00765 392344c13709c3a8f940e74bfb5abf01 217 Pfam PF07650 KH domain 38 107 2.9E-20 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00765 392344c13709c3a8f940e74bfb5abf01 217 SMART SM00322 59 124 2.8E-8 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CWR44_RS00765 392344c13709c3a8f940e74bfb5abf01 217 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.738 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CWR44_RS00765 392344c13709c3a8f940e74bfb5abf01 217 SUPERFAMILY SSF54821 106 205 2.49E-37 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00765 392344c13709c3a8f940e74bfb5abf01 217 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 7.7E-93 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CWR44_RS00765 392344c13709c3a8f940e74bfb5abf01 217 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 2.5E-38 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00765 392344c13709c3a8f940e74bfb5abf01 217 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00765 392344c13709c3a8f940e74bfb5abf01 217 Gene3D G3DSA:3.30.300.20 17 106 1.2E-30 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWR44_RS00765 392344c13709c3a8f940e74bfb5abf01 217 SUPERFAMILY SSF54814 2 105 4.19E-38 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CWR44_RS00765 392344c13709c3a8f940e74bfb5abf01 217 Gene3D G3DSA:3.30.1140.32 107 206 3.7E-35 T 28-03-2018 CWR44_RS02695 1f34d06b6a31ac3be34175ab885da494 289 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 163 3.0E-24 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CWR44_RS02695 1f34d06b6a31ac3be34175ab885da494 289 Gene3D G3DSA:3.40.50.720 37 274 7.0E-21 T 28-03-2018 CWR44_RS02695 1f34d06b6a31ac3be34175ab885da494 289 SUPERFAMILY SSF51735 1 244 1.31E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02695 1f34d06b6a31ac3be34175ab885da494 289 Gene3D G3DSA:3.40.50.720 1 36 3.9E-5 T 28-03-2018 CWR44_RS06225 60b4d003fd4ff6a09f829ebe55c2e061 362 SUPERFAMILY SSF53756 41 360 7.12E-13 T 28-03-2018 CWR44_RS06225 60b4d003fd4ff6a09f829ebe55c2e061 362 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 36 357 1.6E-41 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CWR44_RS06225 60b4d003fd4ff6a09f829ebe55c2e061 362 Gene3D G3DSA:3.40.50.2000 193 324 8.8E-4 T 28-03-2018 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 221 242 2.6E-28 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 2.6E-28 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 2.6E-28 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 190 208 2.6E-28 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 Gene3D G3DSA:4.10.860.10 401 451 0.0029 T 28-03-2018 IPR001943 UVR domain GO:0005515 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 312 3.9E-133 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 SUPERFAMILY SSF47323 338 465 1.7E-30 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 Gene3D G3DSA:1.20.120.640 305 400 1.0E-14 T 28-03-2018 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 SMART SM00840 351 416 4.5E-11 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 Gene3D G3DSA:3.40.50.620 1 304 3.4E-92 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 SUPERFAMILY SSF52374 2 311 8.58E-102 T 28-03-2018 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 Pfam PF09190 DALR domain 351 410 2.0E-13 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 465 8.1E-178 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CWR44_RS05565 8469ad4d2ae484866340bdf6b65bb14b 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 466 38.247 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CWR44_RS02265 bdeec1a143a1f2324936b4868b1ddfc6 71 Pfam PF00403 Heavy-metal-associated domain 8 69 3.8E-20 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS02265 bdeec1a143a1f2324936b4868b1ddfc6 71 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CWR44_RS02265 bdeec1a143a1f2324936b4868b1ddfc6 71 SUPERFAMILY SSF55008 3 70 1.44E-22 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS02265 bdeec1a143a1f2324936b4868b1ddfc6 71 Gene3D G3DSA:3.30.70.100 4 71 2.6E-23 T 28-03-2018 CWR44_RS02265 bdeec1a143a1f2324936b4868b1ddfc6 71 PRINTS PR00944 Copper ion binding protein signature 6 18 1.2E-7 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR44_RS02265 bdeec1a143a1f2324936b4868b1ddfc6 71 PRINTS PR00944 Copper ion binding protein signature 18 31 1.2E-7 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR44_RS02265 bdeec1a143a1f2324936b4868b1ddfc6 71 PRINTS PR00944 Copper ion binding protein signature 57 70 1.2E-7 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR44_RS02265 bdeec1a143a1f2324936b4868b1ddfc6 71 PRINTS PR00944 Copper ion binding protein signature 31 44 1.2E-7 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CWR44_RS02265 bdeec1a143a1f2324936b4868b1ddfc6 71 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 8 70 1.2E-22 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 Pfam PF00288 GHMP kinases N terminal domain 87 149 2.4E-14 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 93 104 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 PRINTS PR00959 Mevalonate kinase family signature 9 33 2.1E-15 T 28-03-2018 CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 PRINTS PR00959 Mevalonate kinase family signature 91 113 2.1E-15 T 28-03-2018 CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 PRINTS PR00959 Mevalonate kinase family signature 263 280 2.1E-15 T 28-03-2018 CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 Gene3D G3DSA:3.30.70.890 169 307 1.3E-26 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 10 278 3.4E-79 T 28-03-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 Gene3D G3DSA:3.30.230.10 3 167 9.1E-26 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 SUPERFAMILY SSF54211 9 186 1.97E-36 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 Pfam PF08544 GHMP kinases C terminal 218 296 2.1E-7 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS05940 1e595efbad8cd9b8789b98e0bcca50e8 307 SUPERFAMILY SSF55060 170 305 9.35E-28 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 Pfam PF03793 PASTA domain 441 501 1.4E-11 T 28-03-2018 IPR005543 PASTA domain CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 Pfam PF03793 PASTA domain 509 570 2.9E-12 T 28-03-2018 IPR005543 PASTA domain CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 Pfam PF03793 PASTA domain 373 435 4.1E-14 T 28-03-2018 IPR005543 PASTA domain CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 SUPERFAMILY SSF56112 7 268 3.73E-79 T 28-03-2018 IPR011009 Protein kinase-like domain CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 SMART SM00740 505 570 5.8E-13 T 28-03-2018 IPR005543 PASTA domain CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 SMART SM00740 368 435 1.2E-16 T 28-03-2018 IPR005543 PASTA domain CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 SMART SM00740 436 504 2.3E-13 T 28-03-2018 IPR005543 PASTA domain CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 SMART SM00220 10 270 2.8E-68 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 Gene3D G3DSA:1.10.510.10 93 346 7.1E-53 T 28-03-2018 CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 Pfam PF00069 Protein kinase domain 10 251 5.0E-57 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 Gene3D G3DSA:3.30.200.20 1 92 9.1E-27 T 28-03-2018 CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 PIRSF PIRSF000654 523 628 36.0 T 28-03-2018 CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 PIRSF PIRSF000654 31 316 4.1E-32 T 28-03-2018 CWR44_RS08505 bd314bcf08465aa52faae0ffcb06031c 675 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CWR44_RS04600 b2ac42c5f66b6b11f8cea931ab596027 67 PIRSF PIRSF037263 1 65 1.1E-34 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CWR44_RS04600 b2ac42c5f66b6b11f8cea931ab596027 67 Pfam PF06107 Bacterial protein of unknown function (DUF951) 5 58 4.6E-29 T 28-03-2018 IPR009296 Protein of unknown function DUF951 CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 Gene3D G3DSA:3.40.50.300 19 182 7.7E-31 T 28-03-2018 CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 Gene3D G3DSA:1.10.8.60 185 255 7.9E-29 T 28-03-2018 CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 Gene3D G3DSA:1.10.10.10 258 328 7.9E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 327 1.5E-142 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 5.6E-33 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 SUPERFAMILY SSF52540 21 253 1.39E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 SMART SM00382 52 183 3.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 4 236 2.1E-114 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 331 163.245 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 SUPERFAMILY SSF46785 258 327 1.63E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11105 974c773dc95c101c583b546a6d2e5727 331 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 325 1.0E-38 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 Pfam PF01297 Zinc-uptake complex component A periplasmic 38 323 2.1E-68 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 PRINTS PR00691 Adhesin B signature 60 78 2.0E-10 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 PRINTS PR00691 Adhesin B signature 259 276 2.0E-10 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 PRINTS PR00691 Adhesin B signature 303 321 2.0E-10 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 PRINTS PR00691 Adhesin B signature 35 56 2.0E-10 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 PRINTS PR00691 Adhesin B signature 79 98 2.0E-10 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 SUPERFAMILY SSF53807 34 325 5.4E-80 T 28-03-2018 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 Gene3D G3DSA:3.40.50.1980 205 325 3.8E-32 T 28-03-2018 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 Gene3D G3DSA:3.40.50.1980 24 204 4.5E-52 T 28-03-2018 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 PRINTS PR00690 Adhesin family signature 66 79 1.7E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 PRINTS PR00690 Adhesin family signature 79 96 1.7E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 PRINTS PR00690 Adhesin family signature 35 53 1.7E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS03945 c83811ce6520b4e7e2815f73eaab3f97 327 PRINTS PR00690 Adhesin family signature 263 281 1.7E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS08710 9044aac2f97c1920b082481e6b3086ef 256 Gene3D G3DSA:3.40.1180.10 10 255 9.3E-90 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR44_RS08710 9044aac2f97c1920b082481e6b3086ef 256 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 197 214 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CWR44_RS08710 9044aac2f97c1920b082481e6b3086ef 256 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 24 252 38.798 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR44_RS08710 9044aac2f97c1920b082481e6b3086ef 256 SUPERFAMILY SSF64005 19 246 7.59E-87 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR44_RS08710 9044aac2f97c1920b082481e6b3086ef 256 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 24 251 1.3E-84 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR44_RS08710 9044aac2f97c1920b082481e6b3086ef 256 Pfam PF01255 Putative undecaprenyl diphosphate synthase 31 251 1.0E-79 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CWR44_RS11055 bd462c19d9e4f6a0ad5d05c462a98d72 423 Gene3D G3DSA:3.30.930.10 1 321 1.1E-69 T 28-03-2018 CWR44_RS11055 bd462c19d9e4f6a0ad5d05c462a98d72 423 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 410 2.3E-154 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CWR44_RS11055 bd462c19d9e4f6a0ad5d05c462a98d72 423 SUPERFAMILY SSF52954 330 420 3.78E-25 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS11055 bd462c19d9e4f6a0ad5d05c462a98d72 423 Gene3D G3DSA:3.40.50.800 322 421 1.4E-19 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS11055 bd462c19d9e4f6a0ad5d05c462a98d72 423 PIRSF PIRSF001549 1 422 1.5E-121 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CWR44_RS11055 bd462c19d9e4f6a0ad5d05c462a98d72 423 Pfam PF13393 Histidyl-tRNA synthetase 7 313 5.5E-47 T 28-03-2018 CWR44_RS11055 bd462c19d9e4f6a0ad5d05c462a98d72 423 Pfam PF03129 Anticodon binding domain 332 421 2.6E-17 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS11055 bd462c19d9e4f6a0ad5d05c462a98d72 423 SUPERFAMILY SSF55681 2 319 4.02E-96 T 28-03-2018 CWR44_RS11055 bd462c19d9e4f6a0ad5d05c462a98d72 423 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 33.138 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CWR44_RS12400 d02180b1f45839febec34451de532f77 401 Pfam PF07537 CamS sex pheromone cAM373 precursor 62 393 2.9E-113 T 28-03-2018 IPR011426 CamS sex pheromone cAM373 CWR44_RS12400 d02180b1f45839febec34451de532f77 401 Gene3D G3DSA:3.10.570.10 41 400 3.0E-119 T 28-03-2018 CWR44_RS12400 d02180b1f45839febec34451de532f77 401 PIRSF PIRSF012509 1 400 2.0E-150 T 28-03-2018 IPR011426 CamS sex pheromone cAM373 CWR44_RS02370 9f231132eec355f8743121e98ead0e63 355 Gene3D G3DSA:3.20.20.70 1 355 8.7E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS02370 9f231132eec355f8743121e98ead0e63 355 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 2 354 1.0E-103 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CWR44_RS02370 9f231132eec355f8743121e98ead0e63 355 SUPERFAMILY SSF51395 1 353 3.05E-91 T 28-03-2018 CWR44_RS02370 9f231132eec355f8743121e98ead0e63 355 PIRSF PIRSF000164 16 355 2.3E-100 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CWR44_RS02370 9f231132eec355f8743121e98ead0e63 355 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 290 310 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CWR44_RS02370 9f231132eec355f8743121e98ead0e63 355 Pfam PF01180 Dihydroorotate dehydrogenase 49 338 2.4E-72 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CWR44_RS02370 9f231132eec355f8743121e98ead0e63 355 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 84 103 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CWR44_RS08825 f1fdd9864a76e770a34d03153618b67a 191 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 187 6.1E-57 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CWR44_RS08825 f1fdd9864a76e770a34d03153618b67a 191 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 82 7.4E-17 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CWR44_RS08825 f1fdd9864a76e770a34d03153618b67a 191 PIRSF PIRSF000847 1 191 1.0E-50 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CWR44_RS08825 f1fdd9864a76e770a34d03153618b67a 191 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CWR44_RS04540 9b00d76107dc35ee0c9e644a2be5254d 185 Gene3D G3DSA:3.40.630.30 5 182 7.7E-27 T 28-03-2018 CWR44_RS04540 9b00d76107dc35ee0c9e644a2be5254d 185 SUPERFAMILY SSF55729 7 175 6.1E-41 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS04540 9b00d76107dc35ee0c9e644a2be5254d 185 Pfam PF13302 Acetyltransferase (GNAT) domain 10 150 1.7E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 475 1.2E-160 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 297 309 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 Pfam PF00571 CBS domain 153 204 3.8E-8 T 28-03-2018 IPR000644 CBS domain CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 Pfam PF00571 CBS domain 97 144 2.4E-8 T 28-03-2018 IPR000644 CBS domain CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 SUPERFAMILY SSF54631 65 207 9.73E-30 T 28-03-2018 CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 1.4E-198 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 PIRSF PIRSF000130 1 488 2.0E-203 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 SMART SM01240 9 475 0.0 T 28-03-2018 CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 SMART SM00116 98 148 4.2E-9 T 28-03-2018 IPR000644 CBS domain CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 SMART SM00116 161 208 7.2E-7 T 28-03-2018 IPR000644 CBS domain CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 SUPERFAMILY SSF51412 219 479 2.75E-119 T 28-03-2018 CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 SUPERFAMILY SSF51412 5 92 2.75E-119 T 28-03-2018 CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 488 82.487 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CWR44_RS04915 2524c56f1606a7e3adc6d7a70f542b2e 488 Gene3D G3DSA:3.20.20.70 3 483 1.8E-109 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS03470 df7844846456a6db9f92a9f929c10619 346 SMART SM00861 7 194 1.7E-55 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR44_RS03470 df7844846456a6db9f92a9f929c10619 346 Pfam PF02780 Transketolase, C-terminal domain 208 330 3.9E-40 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CWR44_RS03470 df7844846456a6db9f92a9f929c10619 346 SUPERFAMILY SSF52922 203 338 9.16E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR44_RS03470 df7844846456a6db9f92a9f929c10619 346 Gene3D G3DSA:3.40.50.920 209 339 9.0E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR44_RS03470 df7844846456a6db9f92a9f929c10619 346 SUPERFAMILY SSF52518 4 218 3.8E-61 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS03470 df7844846456a6db9f92a9f929c10619 346 Gene3D G3DSA:3.40.50.970 3 208 8.2E-62 T 28-03-2018 CWR44_RS03470 df7844846456a6db9f92a9f929c10619 346 Pfam PF02779 Transketolase, pyrimidine binding domain 6 193 1.4E-46 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR44_RS03545 1fed954c62176cf11cecd50691a50cab 69 SUPERFAMILY SSF103473 5 67 2.22E-10 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS03545 1fed954c62176cf11cecd50691a50cab 69 Gene3D G3DSA:1.20.1250.20 1 68 4.1E-11 T 28-03-2018 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 PIRSF PIRSF004557 1 399 7.7E-67 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 SUPERFAMILY SSF103491 3 386 9.29E-68 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 PRINTS PR00303 Preprotein translocase SecY subunit signature 60 80 1.0E-23 T 28-03-2018 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 PRINTS PR00303 Preprotein translocase SecY subunit signature 275 297 1.0E-23 T 28-03-2018 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 PRINTS PR00303 Preprotein translocase SecY subunit signature 14 32 1.0E-23 T 28-03-2018 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 PRINTS PR00303 Preprotein translocase SecY subunit signature 235 254 1.0E-23 T 28-03-2018 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 PRINTS PR00303 Preprotein translocase SecY subunit signature 127 152 1.0E-23 T 28-03-2018 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 PRINTS PR00303 Preprotein translocase SecY subunit signature 330 348 1.0E-23 T 28-03-2018 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 1.0E-23 T 28-03-2018 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 TIGRFAM TIGR02920 acc_sec_Y2: accessory Sec system translocase SecY2 9 395 3.4E-136 T 28-03-2018 IPR014269 Accessory Sec system protein translocase subunit SecY2 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 Pfam PF00344 SecY translocase 62 377 3.6E-44 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 Gene3D G3DSA:1.10.3370.10 2 398 2.4E-62 T 28-03-2018 CWR44_RS03010 772207091a4ad7ad84884d5aa6d59d55 399 Hamap MF_01466 Accessory Sec system protein translocase subunit SecY2 [secY2]. 2 395 27.629 T 28-03-2018 IPR014269 Accessory Sec system protein translocase subunit SecY2 CWR44_RS05375 1ab6d34908d92cd8703976f3206c1673 431 SUPERFAMILY SSF52402 6 205 9.43E-52 T 28-03-2018 CWR44_RS05375 1ab6d34908d92cd8703976f3206c1673 431 SUPERFAMILY SSF56037 347 419 7.59E-14 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR44_RS05375 1ab6d34908d92cd8703976f3206c1673 431 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 2 283 21.354 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWR44_RS05375 1ab6d34908d92cd8703976f3206c1673 431 SMART SM00977 358 425 2.0E-19 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWR44_RS05375 1ab6d34908d92cd8703976f3206c1673 431 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 358 402 6.2E-17 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWR44_RS05375 1ab6d34908d92cd8703976f3206c1673 431 Gene3D G3DSA:3.40.50.620 5 201 3.1E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS05375 1ab6d34908d92cd8703976f3206c1673 431 Pfam PF01171 PP-loop family 14 196 1.3E-59 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CWR44_RS05375 1ab6d34908d92cd8703976f3206c1673 431 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 14 200 1.4E-57 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWR44_RS05375 1ab6d34908d92cd8703976f3206c1673 431 Pfam PF11734 TilS substrate C-terminal domain 360 421 6.9E-10 T 28-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CWR44_RS00710 3955f5f7931ce47c005bf6f35cdd9f0c 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 4.6E-70 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWR44_RS00710 3955f5f7931ce47c005bf6f35cdd9f0c 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CWR44_RS00710 3955f5f7931ce47c005bf6f35cdd9f0c 166 SUPERFAMILY SSF54211 79 159 7.33E-27 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS00710 3955f5f7931ce47c005bf6f35cdd9f0c 166 Gene3D G3DSA:3.30.160.20 10 72 5.6E-29 T 28-03-2018 CWR44_RS00710 3955f5f7931ce47c005bf6f35cdd9f0c 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 6.9E-30 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CWR44_RS00710 3955f5f7931ce47c005bf6f35cdd9f0c 166 SUPERFAMILY SSF54768 7 76 8.58E-25 T 28-03-2018 CWR44_RS00710 3955f5f7931ce47c005bf6f35cdd9f0c 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 36.847 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CWR44_RS00710 3955f5f7931ce47c005bf6f35cdd9f0c 166 Gene3D G3DSA:3.30.230.10 77 166 4.3E-33 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS00710 3955f5f7931ce47c005bf6f35cdd9f0c 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 86 157 1.3E-32 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR44_RS09905 8ff6e1698a8a520f3bb6c448356eb657 258 SUPERFAMILY SSF56784 3 223 2.01E-33 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS09905 8ff6e1698a8a520f3bb6c448356eb657 258 Gene3D G3DSA:3.40.50.1000 2 238 7.5E-16 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS09905 8ff6e1698a8a520f3bb6c448356eb657 258 Pfam PF08282 haloacid dehalogenase-like hydrolase 3 228 1.4E-31 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS09905 8ff6e1698a8a520f3bb6c448356eb657 258 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 219 3.2E-19 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR44_RS10190 fde9c791555df4085f135f5df3733d8c 377 Pfam PF02926 THUMP domain 19 153 2.5E-12 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CWR44_RS10190 fde9c791555df4085f135f5df3733d8c 377 SMART SM00981 55 153 3.6E-8 T 28-03-2018 IPR004114 THUMP domain GO:0003723 CWR44_RS10190 fde9c791555df4085f135f5df3733d8c 377 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 194 205 - T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS10190 fde9c791555df4085f135f5df3733d8c 377 SUPERFAMILY SSF53335 253 371 6.68E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS10190 fde9c791555df4085f135f5df3733d8c 377 SUPERFAMILY SSF53335 142 216 6.68E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS10190 fde9c791555df4085f135f5df3733d8c 377 Gene3D G3DSA:3.40.50.150 159 376 1.4E-33 T 28-03-2018 CWR44_RS10190 fde9c791555df4085f135f5df3733d8c 377 Pfam PF01170 Putative RNA methylase family UPF0020 161 367 4.2E-59 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 SMART SM00228 543 629 0.0038 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 SUPERFAMILY SSF50156 522 638 6.97E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 Gene3D G3DSA:2.40.10.10 431 540 1.0E-29 T 28-03-2018 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 SUPERFAMILY SSF50494 318 537 2.19E-44 T 28-03-2018 IPR009003 Peptidase S1, PA clan CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 Gene3D G3DSA:2.40.10.10 311 430 1.1E-19 T 28-03-2018 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 Pfam PF13365 Trypsin-like peptidase domain 355 503 3.6E-27 T 28-03-2018 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 Pfam PF13180 PDZ domain 562 638 9.7E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 Gene3D G3DSA:2.30.42.10 541 639 1.5E-14 T 28-03-2018 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 PRINTS PR00834 HtrA/DegQ protease family signature 367 379 5.4E-21 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 PRINTS PR00834 HtrA/DegQ protease family signature 474 491 5.4E-21 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 PRINTS PR00834 HtrA/DegQ protease family signature 388 408 5.4E-21 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 PRINTS PR00834 HtrA/DegQ protease family signature 586 598 5.4E-21 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS07620 b63d2f216f643e195c438db781c56b1c 639 PRINTS PR00834 HtrA/DegQ protease family signature 430 454 5.4E-21 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CWR44_RS04585 2da9a34dc4d3b02c9ee2dbc01e575b0f 367 PIRSF PIRSF001434 1 362 3.0E-104 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS04585 2da9a34dc4d3b02c9ee2dbc01e575b0f 367 Gene3D G3DSA:3.90.1150.10 243 275 0.012 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS04585 2da9a34dc4d3b02c9ee2dbc01e575b0f 367 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 359 1.7E-112 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS04585 2da9a34dc4d3b02c9ee2dbc01e575b0f 367 Gene3D G3DSA:3.40.640.10 2 242 1.3E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS04585 2da9a34dc4d3b02c9ee2dbc01e575b0f 367 Gene3D G3DSA:3.90.1150.10 276 364 1.4E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS04585 2da9a34dc4d3b02c9ee2dbc01e575b0f 367 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 185 199 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS04585 2da9a34dc4d3b02c9ee2dbc01e575b0f 367 SUPERFAMILY SSF53383 17 359 4.64E-88 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS00295 f1324645f73814984da5a0a7bc549725 394 SUPERFAMILY SSF55031 171 276 2.75E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS00295 f1324645f73814984da5a0a7bc549725 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 18 337 9.1E-59 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS00295 f1324645f73814984da5a0a7bc549725 394 Gene3D G3DSA:3.40.630.10 1 394 1.2E-57 T 28-03-2018 CWR44_RS00295 f1324645f73814984da5a0a7bc549725 394 Pfam PF07687 Peptidase dimerisation domain 174 265 2.0E-7 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS00295 f1324645f73814984da5a0a7bc549725 394 SUPERFAMILY SSF53187 284 376 2.11E-59 T 28-03-2018 CWR44_RS00295 f1324645f73814984da5a0a7bc549725 394 SUPERFAMILY SSF53187 5 184 2.11E-59 T 28-03-2018 CWR44_RS00295 f1324645f73814984da5a0a7bc549725 394 PIRSF PIRSF037226 1 394 2.5E-158 T 28-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CWR44_RS10940 a64af56247e401a752902a793273c16e 334 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 283 3.5E-74 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CWR44_RS10940 a64af56247e401a752902a793273c16e 334 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 301 1.4E-79 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CWR44_RS10940 a64af56247e401a752902a793273c16e 334 SUPERFAMILY SSF50891 176 290 4.93E-8 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS10940 a64af56247e401a752902a793273c16e 334 SMART SM00797 24 301 8.4E-122 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 Hamap MF_01237 N-acetylneuraminate lyase [nanA]. 5 293 50.473 T 28-03-2018 IPR005264 N-acetylneuraminate lyase GO:0005737|GO:0005975|GO:0008747 KEGG: 00520+4.1.3.3|MetaCyc: PWY-7581|Reactome: R-HSA-4085001 CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 PIRSF PIRSF001365 1 293 6.2E-58 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 Pfam PF00701 Dihydrodipicolinate synthetase family 5 290 2.9E-83 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 1.9E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 1.9E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 1.9E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 1.9E-16 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 SMART SM01130 4 292 6.3E-72 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 Gene3D G3DSA:3.20.20.70 2 293 1.5E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS03225 7806bf7b1f38713d9396590016b6e1b4 293 SUPERFAMILY SSF51569 4 292 4.4E-76 T 28-03-2018 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 Pfam PF00318 Ribosomal protein S2 9 224 4.8E-101 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 SUPERFAMILY SSF52313 6 230 7.19E-100 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 43.511 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 PRINTS PR00395 Ribosomal protein S2 signature 175 186 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 PRINTS PR00395 Ribosomal protein S2 signature 158 175 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 PRINTS PR00395 Ribosomal protein S2 signature 196 210 2.4E-41 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 7.8E-111 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CWR44_RS08690 1f5f69d14693404f98769b9bc9147bbe 262 Gene3D G3DSA:3.40.50.10490 5 260 1.2E-106 T 28-03-2018 CWR44_RS03910 9555c38b92419b948bd3b27bc1181a54 273 Gene3D G3DSA:3.40.50.300 3 242 5.0E-40 T 28-03-2018 CWR44_RS03910 9555c38b92419b948bd3b27bc1181a54 273 SMART SM00382 30 202 8.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03910 9555c38b92419b948bd3b27bc1181a54 273 Pfam PF00005 ABC transporter 22 150 5.9E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS03910 9555c38b92419b948bd3b27bc1181a54 273 SUPERFAMILY SSF52540 6 202 3.04E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11380 025e73f1d081602df2514a703fbb3112 312 SUPERFAMILY SSF64182 16 284 9.68E-66 T 28-03-2018 CWR44_RS11380 025e73f1d081602df2514a703fbb3112 312 Pfam PF02272 DHHA1 domain 228 310 2.6E-12 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWR44_RS11380 025e73f1d081602df2514a703fbb3112 312 Gene3D G3DSA:3.90.1640.10 1 199 1.2E-42 T 28-03-2018 CWR44_RS11380 025e73f1d081602df2514a703fbb3112 312 Pfam PF01368 DHH family 18 155 5.2E-13 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR44_RS01145 a9b2c675308d1319f7cf92c51ef02ec7 431 Pfam PF03553 Na+/H+ antiporter family 237 422 3.2E-10 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CWR44_RS01145 a9b2c675308d1319f7cf92c51ef02ec7 431 Pfam PF03553 Na+/H+ antiporter family 24 211 2.6E-10 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CWR44_RS03785 d84c091278f69cfb22d5fd747f6d79c2 142 Pfam PF02082 Transcriptional regulator 1 81 8.5E-22 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CWR44_RS03785 d84c091278f69cfb22d5fd747f6d79c2 142 SUPERFAMILY SSF46785 2 136 5.85E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03785 d84c091278f69cfb22d5fd747f6d79c2 142 Gene3D G3DSA:1.10.10.10 1 142 4.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS09765 8bb05514716f8fd53313b124ab118497 117 Gene3D G3DSA:1.20.5.220 103 116 4.4E-4 T 28-03-2018 CWR44_RS09765 8bb05514716f8fd53313b124ab118497 117 SUPERFAMILY SSF81330 10 111 7.45E-31 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWR44_RS09765 8bb05514716f8fd53313b124ab118497 117 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 117 25.695 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWR44_RS09765 8bb05514716f8fd53313b124ab118497 117 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CWR44_RS09765 8bb05514716f8fd53313b124ab118497 117 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 72 80 2.0E-11 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWR44_RS09765 8bb05514716f8fd53313b124ab118497 117 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.0E-11 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWR44_RS09765 8bb05514716f8fd53313b124ab118497 117 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 81 90 2.0E-11 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWR44_RS09765 8bb05514716f8fd53313b124ab118497 117 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 114 6.1E-39 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWR44_RS09765 8bb05514716f8fd53313b124ab118497 117 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 116 6.0E-36 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CWR44_RS04260 3601da4a5c76e0f3335c4d4d8a4ec0ae 309 Gene3D G3DSA:1.10.10.10 1 63 4.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04260 3601da4a5c76e0f3335c4d4d8a4ec0ae 309 SUPERFAMILY SSF46785 4 63 1.73E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04260 3601da4a5c76e0f3335c4d4d8a4ec0ae 309 Pfam PF08279 HTH domain 6 60 4.9E-11 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CWR44_RS04260 3601da4a5c76e0f3335c4d4d8a4ec0ae 309 Pfam PF13280 WYL domain 141 305 7.9E-10 T 28-03-2018 IPR026881 WYL domain CWR44_RS10965 01ade3f9b5e8647759bf68e98f42c313 307 Gene3D G3DSA:3.20.20.150 7 278 5.8E-4 T 28-03-2018 CWR44_RS10965 01ade3f9b5e8647759bf68e98f42c313 307 Pfam PF01136 Peptidase family U32 73 304 6.6E-62 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWR44_RS11555 11cd37b3894450b65d0a4346eb0d4098 363 SUPERFAMILY SSF51569 58 359 2.38E-98 T 28-03-2018 CWR44_RS11555 11cd37b3894450b65d0a4346eb0d4098 363 TIGRFAM TIGR01801 CM_A: chorismate mutase 2 101 3.1E-46 T 28-03-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWR44_RS11555 11cd37b3894450b65d0a4346eb0d4098 363 Gene3D G3DSA:1.20.59.10 3 89 5.0E-26 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWR44_RS11555 11cd37b3894450b65d0a4346eb0d4098 363 Pfam PF01817 Chorismate mutase type II 9 86 1.5E-21 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWR44_RS11555 11cd37b3894450b65d0a4346eb0d4098 363 SMART SM00830 9 88 6.9E-27 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWR44_RS11555 11cd37b3894450b65d0a4346eb0d4098 363 Gene3D G3DSA:3.20.20.70 95 356 2.0E-71 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS11555 11cd37b3894450b65d0a4346eb0d4098 363 Pfam PF00793 DAHP synthetase I family 110 354 8.7E-87 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CWR44_RS11555 11cd37b3894450b65d0a4346eb0d4098 363 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 7.2E-115 T 28-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CWR44_RS11555 11cd37b3894450b65d0a4346eb0d4098 363 SUPERFAMILY SSF48600 3 83 5.31E-21 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CWR44_RS03695 ae7d536ffe7a301a9a024da371932272 129 Gene3D G3DSA:3.40.1650.10 3 129 2.1E-38 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CWR44_RS03695 ae7d536ffe7a301a9a024da371932272 129 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 129 31.449 T 28-03-2018 IPR023064 D-ribose pyranase GO:0016872 CWR44_RS03695 ae7d536ffe7a301a9a024da371932272 129 Pfam PF05025 RbsD / FucU transport protein family 1 128 1.3E-46 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CWR44_RS03695 ae7d536ffe7a301a9a024da371932272 129 SUPERFAMILY SSF102546 1 129 1.57E-43 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CWR44_RS06285 db8a72ee5fa93a41edacf3056f10cbe4 320 SUPERFAMILY SSF82549 1 319 4.71E-114 T 28-03-2018 CWR44_RS06285 db8a72ee5fa93a41edacf3056f10cbe4 320 Gene3D G3DSA:3.30.1180.20 179 320 2.9E-41 T 28-03-2018 CWR44_RS06285 db8a72ee5fa93a41edacf3056f10cbe4 320 Gene3D G3DSA:3.40.50.10440 11 178 3.4E-67 T 28-03-2018 CWR44_RS06285 db8a72ee5fa93a41edacf3056f10cbe4 320 Pfam PF02733 Dak1 domain 18 317 4.4E-116 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CWR44_RS06285 db8a72ee5fa93a41edacf3056f10cbe4 320 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 319 6.6E-134 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 CWR44_RS10265 5779021913400f240d6255d34a5af2e5 105 PIRSF PIRSF029904 1 105 3.0E-51 T 28-03-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD CWR44_RS10265 5779021913400f240d6255d34a5af2e5 105 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 102 2.1E-21 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CWR44_RS10265 5779021913400f240d6255d34a5af2e5 105 Gene3D G3DSA:1.10.3420.10 1 105 1.0E-25 T 28-03-2018 CWR44_RS10265 5779021913400f240d6255d34a5af2e5 105 SUPERFAMILY SSF101386 3 102 2.29E-25 T 28-03-2018 CWR44_RS12465 6a9a827ab8da721868691252092299d2 360 SMART SM00710 118 149 2000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CWR44_RS12465 6a9a827ab8da721868691252092299d2 360 SMART SM00710 319 340 3300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CWR44_RS12465 6a9a827ab8da721868691252092299d2 360 SMART SM00710 189 232 2300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CWR44_RS12465 6a9a827ab8da721868691252092299d2 360 SMART SM00710 248 269 60.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CWR44_RS12465 6a9a827ab8da721868691252092299d2 360 SMART SM00710 290 313 2500.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CWR44_RS12465 6a9a827ab8da721868691252092299d2 360 SUPERFAMILY SSF51126 2 329 5.6E-37 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CWR44_RS12465 6a9a827ab8da721868691252092299d2 360 Pfam PF12708 Pectate lyase superfamily protein 3 237 6.1E-13 T 28-03-2018 IPR024535 Pectate lyase superfamily protein CWR44_RS12465 6a9a827ab8da721868691252092299d2 360 Gene3D G3DSA:2.160.20.10 1 360 2.2E-44 T 28-03-2018 IPR012334 Pectin lyase fold CWR44_RS08800 39bab2c222fbadcaeeae5ba82b7602be 424 Gene3D G3DSA:3.30.830.10 240 413 5.7E-30 T 28-03-2018 CWR44_RS08800 39bab2c222fbadcaeeae5ba82b7602be 424 SUPERFAMILY SSF63411 245 419 2.23E-30 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR44_RS08800 39bab2c222fbadcaeeae5ba82b7602be 424 SUPERFAMILY SSF63411 13 226 2.75E-23 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CWR44_RS08800 39bab2c222fbadcaeeae5ba82b7602be 424 Pfam PF05193 Peptidase M16 inactive domain 183 356 1.9E-27 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CWR44_RS08800 39bab2c222fbadcaeeae5ba82b7602be 424 Gene3D G3DSA:3.30.830.10 22 224 4.2E-23 T 28-03-2018 CWR44_RS03675 902f058b2b5aa8972f73018c09985756 282 SUPERFAMILY SSF51735 1 102 1.97E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS03675 902f058b2b5aa8972f73018c09985756 282 Gene3D G3DSA:1.10.1040.10 155 282 3.3E-30 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR44_RS03675 902f058b2b5aa8972f73018c09985756 282 Gene3D G3DSA:3.40.50.720 1 154 2.5E-20 T 28-03-2018 CWR44_RS03675 902f058b2b5aa8972f73018c09985756 282 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 124 8.0E-16 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWR44_RS03675 902f058b2b5aa8972f73018c09985756 282 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 155 277 3.6E-26 T 28-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWR44_RS03675 902f058b2b5aa8972f73018c09985756 282 SUPERFAMILY SSF48179 155 278 4.76E-31 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR44_RS03675 902f058b2b5aa8972f73018c09985756 282 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 277 1.3E-51 T 28-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CWR44_RS00675 17a347529c5bcba8a79acfafce429076 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 5.5E-33 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00675 17a347529c5bcba8a79acfafce429076 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 9.7E-53 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00675 17a347529c5bcba8a79acfafce429076 121 SUPERFAMILY SSF46946 2 112 1.62E-44 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CWR44_RS00675 17a347529c5bcba8a79acfafce429076 121 Gene3D G3DSA:1.10.8.50 1 66 6.7E-26 T 28-03-2018 CWR44_RS00675 17a347529c5bcba8a79acfafce429076 121 Gene3D G3DSA:4.10.910.10 67 85 4.5E-17 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00675 17a347529c5bcba8a79acfafce429076 121 PIRSF PIRSF002134 1 121 9.2E-43 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00675 17a347529c5bcba8a79acfafce429076 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00675 17a347529c5bcba8a79acfafce429076 121 Gene3D G3DSA:4.10.910.10 86 121 3.0E-26 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00675 17a347529c5bcba8a79acfafce429076 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 28.535 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS11910 4d5059f54fa84f6953f83f71c0f2c2c3 246 SMART SM00382 27 209 8.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS11910 4d5059f54fa84f6953f83f71c0f2c2c3 246 Pfam PF00005 ABC transporter 19 161 3.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS11910 4d5059f54fa84f6953f83f71c0f2c2c3 246 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS11910 4d5059f54fa84f6953f83f71c0f2c2c3 246 SUPERFAMILY SSF52540 3 228 1.09E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11910 4d5059f54fa84f6953f83f71c0f2c2c3 246 Gene3D G3DSA:3.40.50.300 1 229 3.4E-61 T 28-03-2018 CWR44_RS04115 9f2c6c06a7f17eaef8ae3c0ff3b05f0c 328 SUPERFAMILY SSF101478 1 322 5.36E-67 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CWR44_RS04115 9f2c6c06a7f17eaef8ae3c0ff3b05f0c 328 Gene3D G3DSA:1.10.4080.10 1 324 8.5E-65 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CWR44_RS04115 9f2c6c06a7f17eaef8ae3c0ff3b05f0c 328 Pfam PF03747 ADP-ribosylglycohydrolase 7 299 8.4E-56 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CWR44_RS06785 e1992788b9d9276789856aa8b46ca964 288 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 280 7.3E-93 T 28-03-2018 IPR003797 DegV CWR44_RS06785 e1992788b9d9276789856aa8b46ca964 288 Gene3D G3DSA:3.30.1180.10 155 287 1.2E-33 T 28-03-2018 CWR44_RS06785 e1992788b9d9276789856aa8b46ca964 288 SUPERFAMILY SSF82549 1 282 6.28E-87 T 28-03-2018 CWR44_RS06785 e1992788b9d9276789856aa8b46ca964 288 Gene3D G3DSA:3.40.50.10170 1 154 1.9E-44 T 28-03-2018 CWR44_RS06785 e1992788b9d9276789856aa8b46ca964 288 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 282 7.9E-81 T 28-03-2018 IPR003797 DegV CWR44_RS06230 9b1b73d388fca14db909302b71afccd4 354 SUPERFAMILY SSF53448 1 255 2.16E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS06230 9b1b73d388fca14db909302b71afccd4 354 Gene3D G3DSA:3.90.550.10 1 298 1.6E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS06230 9b1b73d388fca14db909302b71afccd4 354 Pfam PF00535 Glycosyl transferase family 2 5 139 2.6E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR44_RS12540 51e29e6e52004986ccdfbb99b6aeae23 299 Pfam PF00005 ABC transporter 19 157 4.7E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS12540 51e29e6e52004986ccdfbb99b6aeae23 299 SMART SM00382 27 206 3.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS12540 51e29e6e52004986ccdfbb99b6aeae23 299 SUPERFAMILY SSF52540 3 221 1.04E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS12540 51e29e6e52004986ccdfbb99b6aeae23 299 Gene3D G3DSA:3.40.50.300 1 297 1.5E-49 T 28-03-2018 CWR44_RS03875 1fe930a77a84ce90683a24cff31b9ce8 278 SUPERFAMILY SSF81345 3 263 2.35E-44 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWR44_RS03875 1fe930a77a84ce90683a24cff31b9ce8 278 Pfam PF00950 ABC 3 transport family 11 265 6.2E-78 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CWR44_RS03875 1fe930a77a84ce90683a24cff31b9ce8 278 Gene3D G3DSA:1.10.3470.10 3 274 5.8E-32 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS00510 3f6973a03a19247d1d373dc44cbd134b 456 Pfam PF07670 Nucleoside recognition 142 239 3.6E-9 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR44_RS05180 e378057a2bb75e10e84cc9c535c80e0d 544 SMART SM00642 13 413 7.2E-156 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR44_RS05180 e378057a2bb75e10e84cc9c535c80e0d 544 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 6 541 1.6E-247 T 28-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 CWR44_RS05180 e378057a2bb75e10e84cc9c535c80e0d 544 Pfam PF11941 Domain of unknown function (DUF3459) 458 533 2.7E-6 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CWR44_RS05180 e378057a2bb75e10e84cc9c535c80e0d 544 Gene3D G3DSA:3.90.400.10 120 173 3.9E-26 T 28-03-2018 CWR44_RS05180 e378057a2bb75e10e84cc9c535c80e0d 544 Pfam PF00128 Alpha amylase, catalytic domain 28 371 4.0E-121 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CWR44_RS05180 e378057a2bb75e10e84cc9c535c80e0d 544 Gene3D G3DSA:3.20.20.80 250 497 3.6E-65 T 28-03-2018 CWR44_RS05180 e378057a2bb75e10e84cc9c535c80e0d 544 SUPERFAMILY SSF51011 474 541 1.44E-10 T 28-03-2018 CWR44_RS05180 e378057a2bb75e10e84cc9c535c80e0d 544 SUPERFAMILY SSF51445 5 471 2.71E-146 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWR44_RS05180 e378057a2bb75e10e84cc9c535c80e0d 544 Gene3D G3DSA:3.20.20.80 2 119 2.7E-47 T 28-03-2018 CWR44_RS05180 e378057a2bb75e10e84cc9c535c80e0d 544 Gene3D G3DSA:2.60.40.1180 498 542 3.7E-4 T 28-03-2018 CWR44_RS10535 bc5d58bfeaf32f3363b708fc26146201 76 SUPERFAMILY SSF116842 2 67 2.75E-21 T 28-03-2018 CWR44_RS10535 bc5d58bfeaf32f3363b708fc26146201 76 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 7 62 6.0E-24 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR44_RS10535 bc5d58bfeaf32f3363b708fc26146201 76 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 7 67 15.767 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR44_RS10535 bc5d58bfeaf32f3363b708fc26146201 76 Pfam PF02609 Exonuclease VII small subunit 8 58 4.6E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR44_RS10535 bc5d58bfeaf32f3363b708fc26146201 76 PIRSF PIRSF006488 1 76 5.5E-23 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR44_RS10535 bc5d58bfeaf32f3363b708fc26146201 76 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 49 2.0E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR44_RS10535 bc5d58bfeaf32f3363b708fc26146201 76 Gene3D G3DSA:1.10.287.1040 5 70 7.7E-23 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 TIGRFAM TIGR01882 peptidase-T: peptidase T 4 403 1.8E-166 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 Pfam PF07687 Peptidase dimerisation domain 208 305 8.9E-8 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 138 177 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 Hamap MF_00550 Peptidase T [pepT]. 2 404 54.916 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 SUPERFAMILY SSF55031 209 320 9.94E-42 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 PIRSF PIRSF037215 1 408 3.0E-183 T 28-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 Pfam PF01546 Peptidase family M20/M25/M40 139 401 1.1E-13 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 Gene3D G3DSA:3.40.630.10 1 409 5.8E-49 T 28-03-2018 CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 SUPERFAMILY SSF53187 4 210 7.71E-80 T 28-03-2018 CWR44_RS06755 338d85edba279b9b3381524b5e8af8ef 409 SUPERFAMILY SSF53187 322 403 7.71E-80 T 28-03-2018 CWR44_RS07295 303233a845ea908196b2f30face57d24 118 Gene3D G3DSA:1.20.1250.20 2 117 8.1E-4 T 28-03-2018 CWR44_RS07295 303233a845ea908196b2f30face57d24 118 Pfam PF03334 Na+/H+ antiporter subunit 13 94 1.1E-22 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CWR44_RS07295 303233a845ea908196b2f30face57d24 118 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 108 6.1E-24 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 Gene3D G3DSA:3.30.1360.10 108 224 2.5E-28 T 28-03-2018 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 Gene3D G3DSA:3.30.1360.10 1 86 6.2E-17 T 28-03-2018 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 SUPERFAMILY SSF47789 247 312 7.06E-23 T 28-03-2018 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 SUPERFAMILY SSF55257 172 226 8.11E-32 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 SUPERFAMILY SSF55257 8 50 8.11E-32 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 SUPERFAMILY SSF56553 50 171 3.66E-38 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 6.9E-24 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 SMART SM00662 20 227 2.4E-98 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 35.811 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 312 1.4E-117 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 Gene3D G3DSA:1.10.150.20 241 314 9.4E-26 T 28-03-2018 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 304 2.2E-28 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 314 2.0E-23 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS00665 0f8936d0938bdf960b1518dee6fa22fa 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 152 4.5E-22 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CWR44_RS04735 fd2a1e4266c3617f087b8f2bca65e616 479 Gene3D G3DSA:3.40.630.30 1 185 1.2E-25 T 28-03-2018 CWR44_RS04735 fd2a1e4266c3617f087b8f2bca65e616 479 SUPERFAMILY SSF55729 3 177 8.68E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS04735 fd2a1e4266c3617f087b8f2bca65e616 479 Gene3D G3DSA:3.90.1200.10 276 449 2.3E-13 T 28-03-2018 CWR44_RS04735 fd2a1e4266c3617f087b8f2bca65e616 479 SUPERFAMILY SSF56112 192 432 2.19E-35 T 28-03-2018 IPR011009 Protein kinase-like domain CWR44_RS04735 fd2a1e4266c3617f087b8f2bca65e616 479 Pfam PF01636 Phosphotransferase enzyme family 205 439 1.3E-23 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CWR44_RS04735 fd2a1e4266c3617f087b8f2bca65e616 479 Pfam PF13523 Acetyltransferase (GNAT) domain 15 156 9.1E-23 T 28-03-2018 CWR44_RS07195 fdb77d322a7f0de98b6889c434471690 130 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 5.3E-36 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CWR44_RS07195 fdb77d322a7f0de98b6889c434471690 130 PIRSF PIRSF012565 1 130 1.1E-49 T 28-03-2018 IPR009370 Protein of unknown function DUF1027 CWR44_RS12940 76c1075ce18a4ff8552e53b2743ebef5 235 Pfam PF06737 Transglycosylase-like domain 158 235 4.8E-27 T 28-03-2018 IPR010618 Transglycosylase-like CWR44_RS12940 76c1075ce18a4ff8552e53b2743ebef5 235 Gene3D G3DSA:1.10.530.10 28 235 1.4E-13 T 28-03-2018 CWR44_RS12940 76c1075ce18a4ff8552e53b2743ebef5 235 SUPERFAMILY SSF53955 159 233 2.18E-17 T 28-03-2018 IPR023346 Lysozyme-like domain CWR44_RS00110 76c1075ce18a4ff8552e53b2743ebef5 235 Pfam PF06737 Transglycosylase-like domain 158 235 4.8E-27 T 28-03-2018 IPR010618 Transglycosylase-like CWR44_RS00110 76c1075ce18a4ff8552e53b2743ebef5 235 Gene3D G3DSA:1.10.530.10 28 235 1.4E-13 T 28-03-2018 CWR44_RS00110 76c1075ce18a4ff8552e53b2743ebef5 235 SUPERFAMILY SSF53955 159 233 2.18E-17 T 28-03-2018 IPR023346 Lysozyme-like domain CWR44_RS10310 1d5f26a52a20283016800d8643b358d8 318 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 92 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CWR44_RS10310 1d5f26a52a20283016800d8643b358d8 318 Gene3D G3DSA:1.10.600.10 3 318 3.5E-85 T 28-03-2018 IPR008949 Isoprenoid synthase domain CWR44_RS10310 1d5f26a52a20283016800d8643b358d8 318 SUPERFAMILY SSF48576 7 317 1.58E-78 T 28-03-2018 IPR008949 Isoprenoid synthase domain CWR44_RS10310 1d5f26a52a20283016800d8643b358d8 318 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 200 212 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CWR44_RS10310 1d5f26a52a20283016800d8643b358d8 318 Pfam PF00348 Polyprenyl synthetase 26 265 7.7E-65 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CWR44_RS12745 ac728f432fce433eb73b14f8943af87d 346 Gene3D G3DSA:3.40.718.10 1 346 3.5E-118 T 28-03-2018 CWR44_RS12745 ac728f432fce433eb73b14f8943af87d 346 SUPERFAMILY SSF53659 1 343 5.22E-115 T 28-03-2018 CWR44_RS12745 ac728f432fce433eb73b14f8943af87d 346 SMART SM01329 4 342 8.4E-169 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWR44_RS12745 ac728f432fce433eb73b14f8943af87d 346 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 237 256 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CWR44_RS12745 ac728f432fce433eb73b14f8943af87d 346 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 346 45.134 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CWR44_RS12745 ac728f432fce433eb73b14f8943af87d 346 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 343 2.3E-141 T 28-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CWR44_RS12745 ac728f432fce433eb73b14f8943af87d 346 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 339 1.8E-122 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 Pfam PF16582 Middle domain of thiamine pyrophosphate 185 386 5.5E-15 T 28-03-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 Gene3D G3DSA:3.40.50.1220 206 351 7.2E-22 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 SUPERFAMILY SSF52467 206 359 1.8E-5 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 Gene3D G3DSA:3.40.50.970 1 205 1.2E-49 T 28-03-2018 CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 SUPERFAMILY SSF52518 14 181 7.5E-33 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 11 427 3.8E-137 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 4 548 33.322 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 178 3.9E-31 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 Gene3D G3DSA:3.40.50.970 352 547 1.1E-21 T 28-03-2018 CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 PIRSF PIRSF004983 1 555 3.1E-184 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 419 504 3.8E-6 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR44_RS07710 9ca614517ce6bd9d563ca8fee4eb0611 556 SUPERFAMILY SSF52518 369 538 4.55E-22 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS02930 60fbfa0bdd71f9eccb257f66a95dfac6 394 SUPERFAMILY SSF103473 8 391 2.09E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS02930 60fbfa0bdd71f9eccb257f66a95dfac6 394 Pfam PF07690 Major Facilitator Superfamily 17 322 2.5E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS02930 60fbfa0bdd71f9eccb257f66a95dfac6 394 Gene3D G3DSA:1.20.1250.20 6 197 7.0E-29 T 28-03-2018 CWR44_RS02930 60fbfa0bdd71f9eccb257f66a95dfac6 394 Gene3D G3DSA:1.20.1250.20 198 392 1.4E-18 T 28-03-2018 CWR44_RS08120 f4efae0c8a04d39a39de7ad7e708ad26 309 SUPERFAMILY SSF51695 45 301 1.81E-52 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR44_RS08120 f4efae0c8a04d39a39de7ad7e708ad26 309 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 51 296 9.7E-25 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CWR44_RS08120 f4efae0c8a04d39a39de7ad7e708ad26 309 Gene3D G3DSA:3.20.20.190 24 309 6.9E-48 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR44_RS12415 fc7d139cde121a6cb64ffb94efdce732 231 Pfam PF01884 PcrB family 2 224 1.0E-76 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CWR44_RS12415 fc7d139cde121a6cb64ffb94efdce732 231 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 26.38 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CWR44_RS12415 fc7d139cde121a6cb64ffb94efdce732 231 SUPERFAMILY SSF51395 5 224 1.32E-48 T 28-03-2018 CWR44_RS12415 fc7d139cde121a6cb64ffb94efdce732 231 Gene3D G3DSA:3.20.20.390 1 224 7.9E-27 T 28-03-2018 CWR44_RS12415 fc7d139cde121a6cb64ffb94efdce732 231 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 9 223 3.2E-70 T 28-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 Gene3D G3DSA:3.30.1360.40 76 147 2.1E-17 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 Hamap MF_00173 Arginine repressor [argR]. 1 154 30.619 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 PRINTS PR01467 Bacterial arginine repressor signature 120 135 6.5E-10 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 PRINTS PR01467 Bacterial arginine repressor signature 38 53 6.5E-10 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 PRINTS PR01467 Bacterial arginine repressor signature 90 103 6.5E-10 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 Pfam PF01316 Arginine repressor, DNA binding domain 1 65 6.9E-9 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 SUPERFAMILY SSF55252 83 149 1.44E-18 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 Gene3D G3DSA:1.10.10.10 3 65 3.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 SUPERFAMILY SSF46785 3 69 9.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 94 129 8.0E-11 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWR44_RS02855 72547355a92a4704287eb22b863fe120 154 Pfam PF02863 Arginine repressor, C-terminal domain 89 147 1.5E-16 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CWR44_RS07680 ba23d7fc486e2ad40893a4053e3ef722 194 Pfam PF06338 ComK protein 11 161 1.3E-48 T 28-03-2018 IPR010461 Competence protein ComK GO:0030420 CWR44_RS07680 ba23d7fc486e2ad40893a4053e3ef722 194 PIRSF PIRSF011560 4 194 2.1E-62 T 28-03-2018 IPR010461 Competence protein ComK GO:0030420 CWR44_RS04015 ab5ae7ced61fc2acb21cea2264f5d92c 227 Gene3D G3DSA:3.40.50.880 1 227 2.7E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS04015 ab5ae7ced61fc2acb21cea2264f5d92c 227 Pfam PF01965 DJ-1/PfpI family 27 221 2.6E-11 T 28-03-2018 IPR002818 DJ-1/PfpI CWR44_RS04015 ab5ae7ced61fc2acb21cea2264f5d92c 227 SUPERFAMILY SSF52317 1 224 3.52E-70 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS12735 16a8bf6c24967f658471cf2d5192e84b 334 Gene3D G3DSA:3.90.180.10 4 59 9.2E-5 T 28-03-2018 CWR44_RS12735 16a8bf6c24967f658471cf2d5192e84b 334 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 4.8E-77 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR44_RS12735 16a8bf6c24967f658471cf2d5192e84b 334 Gene3D G3DSA:1.10.1040.10 60 330 1.2E-113 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR44_RS12735 16a8bf6c24967f658471cf2d5192e84b 334 SUPERFAMILY SSF48179 183 329 6.12E-69 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR44_RS12735 16a8bf6c24967f658471cf2d5192e84b 334 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 4.9E-65 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR44_RS12735 16a8bf6c24967f658471cf2d5192e84b 334 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 3.3E-134 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR44_RS12735 16a8bf6c24967f658471cf2d5192e84b 334 SUPERFAMILY SSF51735 3 182 5.78E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS12735 16a8bf6c24967f658471cf2d5192e84b 334 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 45.051 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR44_RS12735 16a8bf6c24967f658471cf2d5192e84b 334 PIRSF PIRSF000116 201 333 2.5E-15 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR44_RS12735 16a8bf6c24967f658471cf2d5192e84b 334 PIRSF PIRSF000116 1 208 6.4E-39 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CWR44_RS09050 91adc2eeae0f984a24259286b237470b 134 SUPERFAMILY SSF103084 4 134 8.76E-27 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CWR44_RS09050 91adc2eeae0f984a24259286b237470b 134 Gene3D G3DSA:3.30.1330.70 2 134 1.6E-21 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CWR44_RS09050 91adc2eeae0f984a24259286b237470b 134 Pfam PF05866 Endodeoxyribonuclease RusA 14 132 6.8E-28 T 28-03-2018 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 CWR44_RS09635 45958ccd0df18628eecf69408d715c59 461 TIGRFAM TIGR01630 psiM2_ORF9: phage uncharacterized protein, C-terminal domain 316 446 3.4E-24 T 28-03-2018 IPR006517 Archaeophage PsiM2, terminase large subunit CWR44_RS09635 45958ccd0df18628eecf69408d715c59 461 Pfam PF17289 Terminase RNaseH-like domain 303 446 4.9E-15 T 28-03-2018 IPR035421 Terminase, large subunit gp17-like CWR44_RS09635 45958ccd0df18628eecf69408d715c59 461 Pfam PF03237 Terminase-like family 59 290 3.4E-20 T 28-03-2018 CWR44_RS11155 6d56c15e0de61ef76cc969cf61734c22 158 Pfam PF16284 Domain of unknown function (DUF4930) 25 158 2.3E-55 T 28-03-2018 IPR032561 Protein of unknown function DUF4930 CWR44_RS09895 0503a3de13fc146ea9141e95a49d0258 420 Pfam PF02388 FemAB family 6 414 4.9E-150 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CWR44_RS09895 0503a3de13fc146ea9141e95a49d0258 420 SUPERFAMILY SSF55729 168 245 7.42E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS09895 0503a3de13fc146ea9141e95a49d0258 420 SUPERFAMILY SSF55729 310 410 7.42E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS09895 0503a3de13fc146ea9141e95a49d0258 420 SUPERFAMILY SSF46589 245 309 1.36E-18 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWR44_RS09895 0503a3de13fc146ea9141e95a49d0258 420 SUPERFAMILY SSF55729 1 165 3.81E-60 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS09895 0503a3de13fc146ea9141e95a49d0258 420 Gene3D G3DSA:3.40.630.30 169 390 1.5E-29 T 28-03-2018 CWR44_RS09895 0503a3de13fc146ea9141e95a49d0258 420 Gene3D G3DSA:3.40.630.30 1 168 1.1E-36 T 28-03-2018 CWR44_RS06310 b69462d61a444f6cab77f66feb256977 348 Pfam PF07859 alpha/beta hydrolase fold 84 292 3.8E-26 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CWR44_RS06310 b69462d61a444f6cab77f66feb256977 348 SUPERFAMILY SSF53474 55 319 6.26E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS06310 b69462d61a444f6cab77f66feb256977 348 Gene3D G3DSA:3.40.50.1820 26 324 5.8E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS12840 96303e8615fd7aeec1c72c601f7681e0 119 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 117 23.88 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWR44_RS12840 96303e8615fd7aeec1c72c601f7681e0 119 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 117 9.5E-34 T 28-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWR44_RS12840 96303e8615fd7aeec1c72c601f7681e0 119 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 91 1.0E-42 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWR44_RS12840 96303e8615fd7aeec1c72c601f7681e0 119 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 117 8.1E-25 T 28-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CWR44_RS12840 96303e8615fd7aeec1c72c601f7681e0 119 SUPERFAMILY SSF56214 1 116 7.46E-29 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CWR44_RS12840 96303e8615fd7aeec1c72c601f7681e0 119 Gene3D G3DSA:3.90.470.20 1 119 5.7E-31 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CWR44_RS12840 96303e8615fd7aeec1c72c601f7681e0 119 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 103 1.6E-20 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CWR44_RS05865 b3b2d6f785615987025fb693a135fcaf 381 Gene3D G3DSA:3.40.47.10 255 380 5.8E-22 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS05865 b3b2d6f785615987025fb693a135fcaf 381 Pfam PF02803 Thiolase, C-terminal domain 265 378 8.4E-33 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CWR44_RS05865 b3b2d6f785615987025fb693a135fcaf 381 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CWR44_RS05865 b3b2d6f785615987025fb693a135fcaf 381 PIRSF PIRSF000429 1 380 1.2E-100 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWR44_RS05865 b3b2d6f785615987025fb693a135fcaf 381 SUPERFAMILY SSF53901 1 254 1.15E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS05865 b3b2d6f785615987025fb693a135fcaf 381 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 377 2.3E-115 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CWR44_RS05865 b3b2d6f785615987025fb693a135fcaf 381 Gene3D G3DSA:3.40.47.10 1 254 2.6E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS05865 b3b2d6f785615987025fb693a135fcaf 381 SUPERFAMILY SSF53901 265 377 8.64E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS05865 b3b2d6f785615987025fb693a135fcaf 381 Pfam PF00108 Thiolase, N-terminal domain 5 251 2.2E-50 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CWR44_RS02335 f3fef2e4d1cdac720eb4c72a9cff664b 78 Gene3D G3DSA:1.10.287.540 2 54 2.0E-19 T 28-03-2018 CWR44_RS02335 f3fef2e4d1cdac720eb4c72a9cff664b 78 SUPERFAMILY SSF158221 1 40 4.05E-12 T 28-03-2018 CWR44_RS02335 f3fef2e4d1cdac720eb4c72a9cff664b 78 Pfam PF05979 Bacterial protein of unknown function (DUF896) 3 65 1.5E-24 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CWR44_RS02335 f3fef2e4d1cdac720eb4c72a9cff664b 78 Hamap MF_01103 UPF0291 protein . 1 58 13.534 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CWR44_RS03980 43bf356482ccf681984fb90ee529f5e2 429 Pfam PF02040 Arsenical pump membrane protein 4 425 1.5E-195 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03980 43bf356482ccf681984fb90ee529f5e2 429 PRINTS PR00758 Arsenical pump membrane protein signature 398 422 2.2E-115 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03980 43bf356482ccf681984fb90ee529f5e2 429 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 2.2E-115 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03980 43bf356482ccf681984fb90ee529f5e2 429 PRINTS PR00758 Arsenical pump membrane protein signature 145 169 2.2E-115 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03980 43bf356482ccf681984fb90ee529f5e2 429 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 2.2E-115 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03980 43bf356482ccf681984fb90ee529f5e2 429 PRINTS PR00758 Arsenical pump membrane protein signature 218 243 2.2E-115 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03980 43bf356482ccf681984fb90ee529f5e2 429 PRINTS PR00758 Arsenical pump membrane protein signature 178 201 2.2E-115 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03980 43bf356482ccf681984fb90ee529f5e2 429 PRINTS PR00758 Arsenical pump membrane protein signature 279 303 2.2E-115 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03980 43bf356482ccf681984fb90ee529f5e2 429 PRINTS PR00758 Arsenical pump membrane protein signature 365 390 2.2E-115 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03980 43bf356482ccf681984fb90ee529f5e2 429 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 4 428 3.7E-227 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS01410 fc06b55d8022fcbee15177f688cfc282 142 Gene3D G3DSA:1.10.10.10 1 138 1.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01410 fc06b55d8022fcbee15177f688cfc282 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 1.4E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS01410 fc06b55d8022fcbee15177f688cfc282 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 1.4E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS01410 fc06b55d8022fcbee15177f688cfc282 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 1.4E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS01410 fc06b55d8022fcbee15177f688cfc282 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 1.4E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS01410 fc06b55d8022fcbee15177f688cfc282 142 SMART SM00347 22 124 7.8E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS01410 fc06b55d8022fcbee15177f688cfc282 142 SUPERFAMILY SSF46785 7 137 7.46E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01410 fc06b55d8022fcbee15177f688cfc282 142 Pfam PF12802 MarR family 29 88 1.5E-8 T 28-03-2018 CWR44_RS09400 131646d05083cfb45211e3af90c37e7b 77 SUPERFAMILY SSF158221 7 43 3.66E-13 T 28-03-2018 CWR44_RS09400 131646d05083cfb45211e3af90c37e7b 77 Gene3D G3DSA:1.10.287.540 5 57 3.0E-24 T 28-03-2018 CWR44_RS09400 131646d05083cfb45211e3af90c37e7b 77 Hamap MF_01103 UPF0291 protein . 1 61 16.66 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CWR44_RS09400 131646d05083cfb45211e3af90c37e7b 77 Pfam PF05979 Bacterial protein of unknown function (DUF896) 8 69 2.7E-32 T 28-03-2018 IPR009242 Protein of unknown function DUF896 CWR44_RS07385 fc94b06e9d14b2419380c34dfea7398e 190 Pfam PF09335 SNARE associated Golgi protein 33 151 1.4E-15 T 28-03-2018 IPR032816 SNARE associated Golgi protein CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 Gene3D G3DSA:3.40.50.1380 1 190 1.2E-69 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 SUPERFAMILY SSF52335 2 190 1.57E-66 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 PIRSF PIRSF000414 1 492 1.4E-190 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 Pfam PF02142 MGS-like domain 13 128 7.1E-29 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 SUPERFAMILY SSF53927 193 492 6.62E-116 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 Gene3D G3DSA:3.40.140.20 199 341 4.5E-51 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 Gene3D G3DSA:3.40.140.20 342 482 1.8E-45 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 SMART SM00798 133 427 5.8E-171 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 SMART SM00851 13 128 8.0E-56 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 2 492 4.8E-190 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 Pfam PF01808 AICARFT/IMPCHase bienzyme 133 426 8.0E-107 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS07870 ed82ec1e0a1eff931c01543a9fc333ce 492 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 1 492 41.144 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS09610 198c28ec622d0a183c01040160cde70a 238 SUPERFAMILY SSF52402 1 215 3.09E-66 T 28-03-2018 CWR44_RS09610 198c28ec622d0a183c01040160cde70a 238 PIRSF PIRSF006293 1 219 2.5E-81 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CWR44_RS09610 198c28ec622d0a183c01040160cde70a 238 Gene3D G3DSA:3.40.50.620 1 222 1.2E-53 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS09610 198c28ec622d0a183c01040160cde70a 238 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 216 48.832 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CWR44_RS09610 198c28ec622d0a183c01040160cde70a 238 Pfam PF06508 Queuosine biosynthesis protein QueC 3 210 3.5E-83 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CWR44_RS09610 198c28ec622d0a183c01040160cde70a 238 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 203 2.1E-83 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CWR44_RS10085 a10c3edf631962c0073fc8031c3d6d26 355 Gene3D G3DSA:3.40.50.2000 2 185 2.3E-32 T 28-03-2018 CWR44_RS10085 a10c3edf631962c0073fc8031c3d6d26 355 SUPERFAMILY SSF53756 3 350 8.7E-83 T 28-03-2018 CWR44_RS10085 a10c3edf631962c0073fc8031c3d6d26 355 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 354 26.361 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR44_RS10085 a10c3edf631962c0073fc8031c3d6d26 355 Gene3D G3DSA:3.40.50.2000 186 343 4.1E-24 T 28-03-2018 CWR44_RS10085 a10c3edf631962c0073fc8031c3d6d26 355 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 335 1.1E-24 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWR44_RS10085 a10c3edf631962c0073fc8031c3d6d26 355 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 144 2.2E-38 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR44_RS06035 c3e342e7bfb4d30c2271e4b52db394df 499 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 492 7.8E-215 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS06035 c3e342e7bfb4d30c2271e4b52db394df 499 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 3 492 51.299 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS06035 c3e342e7bfb4d30c2271e4b52db394df 499 SUPERFAMILY SSF51905 4 274 6.22E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS06035 c3e342e7bfb4d30c2271e4b52db394df 499 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 9 489 3.6E-188 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS06035 c3e342e7bfb4d30c2271e4b52db394df 499 Gene3D G3DSA:3.50.50.60 1 435 8.5E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 SMART SM00896 708 800 2.0E-40 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Pfam PF03483 B3/4 domain 221 392 1.3E-65 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Pfam PF01588 Putative tRNA binding domain 45 151 4.6E-25 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 SUPERFAMILY SSF56037 209 401 1.44E-69 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 SMART SM00873 220 393 2.1E-85 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 800 5.7E-268 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Pfam PF03484 tRNA synthetase B5 domain 413 478 3.5E-21 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 SMART SM00874 410 478 1.4E-28 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Gene3D G3DSA:3.30.930.10 497 695 1.7E-37 T 28-03-2018 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Gene3D G3DSA:3.30.70.380 704 800 8.8E-24 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Gene3D G3DSA:2.40.50.140 54 160 3.1E-41 T 28-03-2018 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 795 46.788 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 SUPERFAMILY SSF50249 41 200 6.86E-46 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Gene3D G3DSA:3.30.56.10 1 53 1.4E-10 T 28-03-2018 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 SUPERFAMILY SSF54991 703 800 4.32E-28 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Gene3D G3DSA:3.30.56.10 408 482 3.8E-24 T 28-03-2018 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 SUPERFAMILY SSF55681 474 696 2.98E-52 T 28-03-2018 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 SUPERFAMILY SSF46955 412 482 3.66E-20 T 28-03-2018 IPR009061 Putative DNA-binding domain CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Pfam PF03147 Ferredoxin-fold anticodon binding domain 708 800 1.5E-26 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CWR44_RS08175 cbd0ec8edc7cfc61edb5197c439eb984 800 Gene3D G3DSA:3.50.40.10 203 404 7.8E-72 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CWR44_RS01230 140bea82421c8dfe9616aa73e3ecb783 158 Gene3D G3DSA:3.10.129.10 1 143 8.1E-18 T 28-03-2018 CWR44_RS01230 140bea82421c8dfe9616aa73e3ecb783 158 SUPERFAMILY SSF54637 1 154 1.85E-35 T 28-03-2018 IPR029069 HotDog domain CWR44_RS01230 140bea82421c8dfe9616aa73e3ecb783 158 Pfam PF13279 Thioesterase-like superfamily 11 127 2.1E-16 T 28-03-2018 CWR44_RS07110 69a6d9bd83ba7baef74ce35025b61e02 341 SMART SM00930 262 338 7.0E-24 T 28-03-2018 IPR018449 NIL domain CWR44_RS07110 69a6d9bd83ba7baef74ce35025b61e02 341 Gene3D G3DSA:3.40.50.300 1 255 2.5E-77 T 28-03-2018 CWR44_RS07110 69a6d9bd83ba7baef74ce35025b61e02 341 SMART SM00382 30 218 7.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS07110 69a6d9bd83ba7baef74ce35025b61e02 341 Gene3D G3DSA:3.30.70.260 256 340 2.1E-20 T 28-03-2018 CWR44_RS07110 69a6d9bd83ba7baef74ce35025b61e02 341 Pfam PF00005 ABC transporter 21 169 3.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS07110 69a6d9bd83ba7baef74ce35025b61e02 341 SUPERFAMILY SSF55021 248 340 8.7E-22 T 28-03-2018 CWR44_RS07110 69a6d9bd83ba7baef74ce35025b61e02 341 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS07110 69a6d9bd83ba7baef74ce35025b61e02 341 Pfam PF09383 NIL domain 265 337 3.6E-15 T 28-03-2018 IPR018449 NIL domain CWR44_RS07110 69a6d9bd83ba7baef74ce35025b61e02 341 SUPERFAMILY SSF52540 1 240 2.59E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS01560 8a7583df518a5804dffa46a662b76fdc 198 SUPERFAMILY SSF52833 1 119 9.5E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS01560 8a7583df518a5804dffa46a662b76fdc 198 SUPERFAMILY SSF52833 149 198 9.5E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS01560 8a7583df518a5804dffa46a662b76fdc 198 Gene3D G3DSA:3.40.30.10 29 198 2.4E-30 T 28-03-2018 CWR44_RS01560 8a7583df518a5804dffa46a662b76fdc 198 Pfam PF13462 Thioredoxin 35 198 1.7E-25 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS08615 c820965545e04b22f1afaf9195aa9655 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 4 116 32.329 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08615 c820965545e04b22f1afaf9195aa9655 116 PRINTS PR00061 Ribosomal protein L19 signature 6 35 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08615 c820965545e04b22f1afaf9195aa9655 116 PRINTS PR00061 Ribosomal protein L19 signature 90 115 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08615 c820965545e04b22f1afaf9195aa9655 116 PRINTS PR00061 Ribosomal protein L19 signature 36 65 1.1E-42 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08615 c820965545e04b22f1afaf9195aa9655 116 Pfam PF01245 Ribosomal protein L19 6 114 5.9E-52 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08615 c820965545e04b22f1afaf9195aa9655 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 5 115 6.5E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08615 c820965545e04b22f1afaf9195aa9655 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 88 103 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08615 c820965545e04b22f1afaf9195aa9655 116 SUPERFAMILY SSF50104 3 115 1.0E-47 T 28-03-2018 IPR008991 Translation protein SH3-like domain CWR44_RS08615 c820965545e04b22f1afaf9195aa9655 116 PIRSF PIRSF002191 1 116 2.4E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS02885 dc0a65faa8527ff2d4e29647c9ee35cb 720 SUPERFAMILY SSF54001 604 717 4.32E-17 T 28-03-2018 CWR44_RS02885 dc0a65faa8527ff2d4e29647c9ee35cb 720 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 429 567 5.2E-19 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR44_RS02885 dc0a65faa8527ff2d4e29647c9ee35cb 720 Gene3D G3DSA:1.10.530.10 416 572 1.2E-35 T 28-03-2018 CWR44_RS02885 dc0a65faa8527ff2d4e29647c9ee35cb 720 Pfam PF05257 CHAP domain 608 694 6.6E-16 T 28-03-2018 IPR007921 CHAP domain CWR44_RS02885 dc0a65faa8527ff2d4e29647c9ee35cb 720 SMART SM00047 412 572 9.9E-45 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR44_RS03185 0ba77790c6c37942d1dd06854a1c8a3f 255 Gene3D G3DSA:1.10.3720.10 4 252 2.9E-32 T 28-03-2018 CWR44_RS03185 0ba77790c6c37942d1dd06854a1c8a3f 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 245 1.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03185 0ba77790c6c37942d1dd06854a1c8a3f 255 SUPERFAMILY SSF161098 57 243 1.31E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS00325 17dfda98b17a315c9950d0bb4817c1e7 236 Gene3D G3DSA:3.40.50.1580 12 235 3.0E-51 T 28-03-2018 CWR44_RS00325 17dfda98b17a315c9950d0bb4817c1e7 236 Pfam PF01048 Phosphorylase superfamily 18 226 1.2E-34 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWR44_RS00325 17dfda98b17a315c9950d0bb4817c1e7 236 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 4 236 40.936 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CWR44_RS00325 17dfda98b17a315c9950d0bb4817c1e7 236 SUPERFAMILY SSF53167 5 235 1.02E-87 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWR44_RS00325 17dfda98b17a315c9950d0bb4817c1e7 236 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 64 79 - T 28-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CWR44_RS00325 17dfda98b17a315c9950d0bb4817c1e7 236 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 7 234 3.9E-93 T 28-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CWR44_RS09600 39843921780d51246276fac380713e38 197 SUPERFAMILY SSF110849 5 159 1.74E-19 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWR44_RS09600 39843921780d51246276fac380713e38 197 Pfam PF02195 ParB-like nuclease domain 9 96 1.2E-11 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWR44_RS09600 39843921780d51246276fac380713e38 197 SMART SM00470 8 97 6.3E-10 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWR44_RS09600 39843921780d51246276fac380713e38 197 Gene3D G3DSA:3.90.1530.10 2 99 2.6E-16 T 28-03-2018 CWR44_RS12000 7daee636c210e23f327724dcb061a775 156 Pfam PF00588 SpoU rRNA Methylase family 4 144 6.3E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CWR44_RS12000 7daee636c210e23f327724dcb061a775 156 SUPERFAMILY SSF75217 4 154 7.85E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR44_RS12000 7daee636c210e23f327724dcb061a775 156 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 4 155 9.7E-64 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CWR44_RS12000 7daee636c210e23f327724dcb061a775 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 153 34.694 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CWR44_RS12000 7daee636c210e23f327724dcb061a775 156 PIRSF PIRSF029256 2 156 1.7E-67 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CWR44_RS12000 7daee636c210e23f327724dcb061a775 156 Gene3D G3DSA:3.40.1280.10 1 156 7.7E-40 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR44_RS12615 1a988c884c9929b0a3229ad154dd529a 95 PRINTS PR00297 10kDa chaperonin signature 2 17 5.8E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR44_RS12615 1a988c884c9929b0a3229ad154dd529a 95 PRINTS PR00297 10kDa chaperonin signature 24 45 5.8E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR44_RS12615 1a988c884c9929b0a3229ad154dd529a 95 PRINTS PR00297 10kDa chaperonin signature 59 71 5.8E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR44_RS12615 1a988c884c9929b0a3229ad154dd529a 95 PRINTS PR00297 10kDa chaperonin signature 80 93 5.8E-27 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR44_RS12615 1a988c884c9929b0a3229ad154dd529a 95 Gene3D G3DSA:2.30.33.40 1 94 2.9E-34 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR44_RS12615 1a988c884c9929b0a3229ad154dd529a 95 SMART SM00883 1 93 2.6E-50 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR44_RS12615 1a988c884c9929b0a3229ad154dd529a 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CWR44_RS12615 1a988c884c9929b0a3229ad154dd529a 95 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 6.9E-34 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR44_RS12615 1a988c884c9929b0a3229ad154dd529a 95 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 24.204 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CWR44_RS12615 1a988c884c9929b0a3229ad154dd529a 95 SUPERFAMILY SSF50129 1 94 1.59E-31 T 28-03-2018 IPR011032 GroES-like CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 SMART SM00957 4 388 3.7E-261 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 503 1.3E-240 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 SUPERFAMILY SSF52540 403 575 1.49E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 Gene3D G3DSA:1.10.3060.10 698 793 2.1E-22 T 28-03-2018 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 Gene3D G3DSA:1.10.3060.10 591 697 9.1E-28 T 28-03-2018 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 Hamap MF_01382 Protein translocase subunit SecA [secA]. 3 784 19.087 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 Pfam PF07517 SecA DEAD-like domain 7 388 6.0E-119 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 PRINTS PR00906 SecA protein signature 174 194 7.6E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 PRINTS PR00906 SecA protein signature 105 119 7.6E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 PRINTS PR00906 SecA protein signature 362 379 7.6E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 PRINTS PR00906 SecA protein signature 67 91 7.6E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 PRINTS PR00906 SecA protein signature 325 347 7.6E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 PRINTS PR00906 SecA protein signature 399 412 7.6E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 PRINTS PR00906 SecA protein signature 121 131 7.6E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 SUPERFAMILY SSF52540 354 401 1.34E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 SUPERFAMILY SSF52540 10 232 1.34E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 Gene3D G3DSA:3.40.50.300 285 402 1.1E-8 T 28-03-2018 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 Gene3D G3DSA:3.40.50.300 6 276 1.3E-49 T 28-03-2018 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 Pfam PF01043 SecA preprotein cross-linking domain 236 344 9.3E-41 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 Pfam PF07516 SecA Wing and Scaffold domain 574 780 7.0E-58 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 Pfam PF02810 SEC-C motif 825 843 3.9E-10 T 28-03-2018 IPR004027 SEC-C motif CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 SUPERFAMILY SSF81767 231 354 2.09E-47 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 ProSitePatterns PS01312 SecA family signature. 486 501 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 Gene3D G3DSA:3.40.50.300 403 590 1.5E-54 T 28-03-2018 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 SMART SM00958 232 344 2.8E-66 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 SUPERFAMILY SSF81886 577 792 3.66E-74 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWR44_RS06805 45c0cd0daa1c41b4810fa076284de295 845 SUPERFAMILY SSF81886 821 833 3.66E-74 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWR44_RS02485 5e4dfbac7e52b57bb3dff5b6b2d2e880 234 Gene3D G3DSA:1.10.10.10 2 73 3.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02485 5e4dfbac7e52b57bb3dff5b6b2d2e880 234 SMART SM00866 87 227 2.1E-31 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR44_RS02485 5e4dfbac7e52b57bb3dff5b6b2d2e880 234 SMART SM00345 7 66 8.9E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS02485 5e4dfbac7e52b57bb3dff5b6b2d2e880 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 3.8E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS02485 5e4dfbac7e52b57bb3dff5b6b2d2e880 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 9.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS02485 5e4dfbac7e52b57bb3dff5b6b2d2e880 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 9.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS02485 5e4dfbac7e52b57bb3dff5b6b2d2e880 234 SUPERFAMILY SSF46785 3 70 1.09E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02485 5e4dfbac7e52b57bb3dff5b6b2d2e880 234 Gene3D G3DSA:3.40.1410.10 74 234 1.3E-33 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR44_RS02485 5e4dfbac7e52b57bb3dff5b6b2d2e880 234 SUPERFAMILY SSF64288 76 230 5.65E-39 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR44_RS02485 5e4dfbac7e52b57bb3dff5b6b2d2e880 234 Pfam PF07702 UTRA domain 88 223 1.9E-29 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR44_RS02735 8f4df267f9e6e4853c88a19b37247c90 369 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 179 2.0E-13 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CWR44_RS02735 8f4df267f9e6e4853c88a19b37247c90 369 SUPERFAMILY SSF51735 2 212 1.17E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02735 8f4df267f9e6e4853c88a19b37247c90 369 Gene3D G3DSA:3.40.50.720 1 216 7.7E-15 T 28-03-2018 CWR44_RS02735 8f4df267f9e6e4853c88a19b37247c90 369 Gene3D G3DSA:2.60.120.10 245 368 2.5E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWR44_RS02735 8f4df267f9e6e4853c88a19b37247c90 369 SUPERFAMILY SSF51182 239 366 1.26E-25 T 28-03-2018 IPR011051 RmlC-like cupin domain CWR44_RS03850 1fbccf6c0c4dd729ad465b97498d19e1 230 SUPERFAMILY SSF53335 2 194 5.27E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS03850 1fbccf6c0c4dd729ad465b97498d19e1 230 Gene3D G3DSA:3.40.50.150 1 226 1.4E-20 T 28-03-2018 CWR44_RS03850 1fbccf6c0c4dd729ad465b97498d19e1 230 Pfam PF13489 Methyltransferase domain 20 183 1.4E-14 T 28-03-2018 CWR44_RS01965 f51adfe19bf63accb7cf0602e4c2d9a1 332 Pfam PF00899 ThiF family 4 239 2.7E-54 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CWR44_RS01965 f51adfe19bf63accb7cf0602e4c2d9a1 332 Gene3D G3DSA:3.40.50.720 1 243 4.1E-59 T 28-03-2018 CWR44_RS01965 f51adfe19bf63accb7cf0602e4c2d9a1 332 SUPERFAMILY SSF69572 1 318 3.14E-73 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CWR44_RS06870 3ad68fc2a90c74eade688fb59741b14a 304 PIRSF PIRSF005052 12 300 2.8E-111 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CWR44_RS06870 3ad68fc2a90c74eade688fb59741b14a 304 SUPERFAMILY SSF52540 11 170 2.47E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06870 3ad68fc2a90c74eade688fb59741b14a 304 Gene3D G3DSA:3.40.50.300 13 169 5.6E-9 T 28-03-2018 CWR44_RS06870 3ad68fc2a90c74eade688fb59741b14a 304 Pfam PF03668 P-loop ATPase protein family 13 295 7.7E-103 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CWR44_RS06870 3ad68fc2a90c74eade688fb59741b14a 304 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 12 298 40.9 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CWR44_RS00860 bba22d4c7ee1c4cd67873ca589870b39 253 SUPERFAMILY SSF54593 3 154 2.09E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS00860 bba22d4c7ee1c4cd67873ca589870b39 253 Gene3D G3DSA:3.10.180.10 3 141 2.0E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS00860 bba22d4c7ee1c4cd67873ca589870b39 253 Pfam PF13468 Glyoxalase-like domain 5 191 7.4E-30 T 28-03-2018 IPR025870 Glyoxalase-like domain CWR44_RS09785 24959f3a6098a62ef229edcabe7ca435 99 SUPERFAMILY SSF89360 1 82 2.35E-9 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CWR44_RS09785 24959f3a6098a62ef229edcabe7ca435 99 Gene3D G3DSA:2.60.300.12 1 98 1.4E-8 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CWR44_RS09785 24959f3a6098a62ef229edcabe7ca435 99 PIRSF PIRSF034852 1 99 5.6E-32 T 28-03-2018 IPR008326 Uncharacterised conserved protein UCP034852 CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 SUPERFAMILY SSF103473 9 195 3.66E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 SUPERFAMILY SSF103473 240 441 3.66E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 PRINTS PR01036 Tetracycline resistance protein TetB signature 388 407 8.7E-12 T 28-03-2018 CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 8.7E-12 T 28-03-2018 CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 PRINTS PR01036 Tetracycline resistance protein TetB signature 220 238 8.7E-12 T 28-03-2018 CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 8.7E-12 T 28-03-2018 CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 8.7E-12 T 28-03-2018 CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 PRINTS PR01036 Tetracycline resistance protein TetB signature 348 368 8.7E-12 T 28-03-2018 CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 Gene3D G3DSA:1.20.1250.20 253 442 5.1E-22 T 28-03-2018 CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 Gene3D G3DSA:1.20.1250.20 4 195 7.4E-25 T 28-03-2018 CWR44_RS00480 c179ec3c89e18b2eb83913a4994dd29d 442 Pfam PF07690 Major Facilitator Superfamily 12 397 9.5E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS09825 8cf066011cb14186b61de75a730b852d 168 SUPERFAMILY SSF55068 2 157 2.88E-66 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS09825 8cf066011cb14186b61de75a730b852d 168 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 5 155 1.6E-58 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS09825 8cf066011cb14186b61de75a730b852d 168 Pfam PF01625 Peptide methionine sulfoxide reductase 5 156 2.9E-60 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS09825 8cf066011cb14186b61de75a730b852d 168 Gene3D G3DSA:3.30.1060.10 1 167 1.6E-63 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS09825 8cf066011cb14186b61de75a730b852d 168 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 3 162 35.874 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS04820 f31c40cc087a2ec8dd3165e2ac17a114 127 Pfam PF14526 Integron-associated effector binding protein 14 123 1.2E-6 T 28-03-2018 IPR029441 Integron-associated effector binding protein CWR44_RS04820 f31c40cc087a2ec8dd3165e2ac17a114 127 Gene3D G3DSA:3.20.80.10 5 127 1.9E-11 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CWR44_RS11170 46a8fd0abc3a584afbda2040be5b3a79 228 SUPERFAMILY SSF47781 16 89 4.45E-6 T 28-03-2018 IPR010994 RuvA domain 2-like CWR44_RS11170 46a8fd0abc3a584afbda2040be5b3a79 228 TIGRFAM TIGR00608 radc: DNA repair protein RadC 12 223 1.6E-70 T 28-03-2018 IPR001405 RadC protein CWR44_RS11170 46a8fd0abc3a584afbda2040be5b3a79 228 SUPERFAMILY SSF102712 125 193 1.26E-5 T 28-03-2018 CWR44_RS11170 46a8fd0abc3a584afbda2040be5b3a79 228 Gene3D G3DSA:3.40.140.10 99 224 5.0E-50 T 28-03-2018 CWR44_RS11170 46a8fd0abc3a584afbda2040be5b3a79 228 Pfam PF04002 RadC-like JAB domain 103 222 1.1E-46 T 28-03-2018 IPR025657 RadC-like JAB domain CWR44_RS11170 46a8fd0abc3a584afbda2040be5b3a79 228 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 28-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CWR44_RS09125 a1acbc3c288009aa46602f03923ce100 422 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 46 379 5.4E-92 T 28-03-2018 IPR006427 Phage portal protein, HK97 CWR44_RS09125 a1acbc3c288009aa46602f03923ce100 422 Pfam PF04860 Phage portal protein 53 373 3.2E-66 T 28-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 SUPERFAMILY SSF55973 246 396 5.1E-70 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 SUPERFAMILY SSF55973 124 245 2.35E-50 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 Gene3D G3DSA:3.30.300.10 13 144 1.2E-42 T 28-03-2018 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 Gene3D G3DSA:3.30.300.10 145 246 1.3E-44 T 28-03-2018 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 396 58.083 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 128 138 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 9.4E-186 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 1.7E-41 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 246 385 1.7E-70 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 Pfam PF02772 S-adenosylmethionine synthetase, central domain 127 244 3.5E-46 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 PIRSF PIRSF000497 1 397 2.0E-175 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 272 280 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 Gene3D G3DSA:3.30.300.10 259 398 1.1E-48 T 28-03-2018 CWR44_RS11805 51614e58d37d6db0aab3673c3edc7458 398 SUPERFAMILY SSF55973 5 111 2.94E-46 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 Gene3D G3DSA:3.30.930.10 149 493 6.5E-109 T 28-03-2018 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 11 496 46.215 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 495 6.4E-223 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 SUPERFAMILY SSF55681 155 494 2.39E-125 T 28-03-2018 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 Pfam PF00152 tRNA synthetases class II (D, K and N) 157 493 1.3E-84 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 SUPERFAMILY SSF50249 4 148 4.95E-42 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 Gene3D G3DSA:2.40.50.140 5 148 2.6E-40 T 28-03-2018 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 Pfam PF01336 OB-fold nucleic acid binding domain 61 139 4.2E-14 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 192 202 4.7E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 208 224 4.7E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 378 394 4.7E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 237 250 4.7E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 255 272 4.7E-40 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS05415 e4d3c85659d010abcad7431ecee6d586 496 PIRSF PIRSF039101 1 496 3.8E-202 T 28-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CWR44_RS05245 f84d4620cb022423e4477e97ea6818bb 109 SUPERFAMILY SSF54913 1 108 4.45E-14 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CWR44_RS05245 f84d4620cb022423e4477e97ea6818bb 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 7.2E-55 T 28-03-2018 IPR010375 Cyclic-di-AMP receptor CWR44_RS05245 f84d4620cb022423e4477e97ea6818bb 109 Gene3D G3DSA:3.30.70.120 1 109 5.0E-15 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 Pfam PF11907 Domain of unknown function (DUF3427) 686 951 1.4E-68 T 28-03-2018 IPR021835 Protein of unknown function DUF3427 CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 Pfam PF00271 Helicase conserved C-terminal domain 455 545 2.7E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 Gene3D G3DSA:3.40.50.300 431 750 2.3E-19 T 28-03-2018 CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 Pfam PF13091 PLD-like domain 53 176 3.2E-14 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 Gene3D G3DSA:3.40.50.300 214 390 7.1E-28 T 28-03-2018 CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 SMART SM00490 466 547 9.3E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 SUPERFAMILY SSF52540 270 568 9.01E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 SMART SM00487 220 401 1.7E-15 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 Gene3D G3DSA:3.30.870.10 28 213 3.2E-16 T 28-03-2018 CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 Pfam PF04851 Type III restriction enzyme, res subunit 222 374 4.6E-34 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CWR44_RS01880 2bd4441ed93c10360c69c57eac08ccf2 954 SUPERFAMILY SSF56024 36 182 3.08E-13 T 28-03-2018 CWR44_RS01435 0d8ecf717e869e58acf268a166359605 124 PIRSF PIRSF032441 1 124 1.7E-44 T 28-03-2018 IPR016996 Uncharacterised conserved protein UCP032441 CWR44_RS01435 0d8ecf717e869e58acf268a166359605 124 Pfam PF08349 Protein of unknown function (DUF1722) 15 122 1.3E-21 T 28-03-2018 IPR013560 Domain of unknown function DUF1722 CWR44_RS00925 42ce5773b50346257805489620b7a0f0 201 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS00925 42ce5773b50346257805489620b7a0f0 201 Gene3D G3DSA:3.40.50.300 1 201 4.3E-49 T 28-03-2018 CWR44_RS00925 42ce5773b50346257805489620b7a0f0 201 SUPERFAMILY SSF52540 8 199 7.38E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00925 42ce5773b50346257805489620b7a0f0 201 SMART SM00382 23 201 4.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS00925 42ce5773b50346257805489620b7a0f0 201 Pfam PF00005 ABC transporter 25 154 1.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS05380 45745a530237b669d342d29f79d2d1a7 179 Gene3D G3DSA:3.40.50.2020 1 179 7.8E-49 T 28-03-2018 CWR44_RS05380 45745a530237b669d342d29f79d2d1a7 179 Pfam PF00156 Phosphoribosyl transferase domain 9 159 4.1E-25 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR44_RS05380 45745a530237b669d342d29f79d2d1a7 179 SUPERFAMILY SSF53271 2 177 2.88E-58 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWR44_RS05380 45745a530237b669d342d29f79d2d1a7 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 172 4.9E-65 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CWR44_RS11445 664a9d65881fff3de3314eafdca11efa 378 SUPERFAMILY SSF53383 1 372 4.54E-85 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS11445 664a9d65881fff3de3314eafdca11efa 378 Pfam PF00266 Aminotransferase class-V 2 362 2.1E-59 T 28-03-2018 IPR000192 Aminotransferase class V domain CWR44_RS11445 664a9d65881fff3de3314eafdca11efa 378 Gene3D G3DSA:3.40.640.10 1 226 1.2E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS11445 664a9d65881fff3de3314eafdca11efa 378 PIRSF PIRSF005572 1 377 9.8E-103 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWR44_RS11445 664a9d65881fff3de3314eafdca11efa 378 Gene3D G3DSA:3.90.1150.10 227 378 8.6E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 Pfam PF07516 SecA Wing and Scaffold domain 582 779 5.0E-21 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 Pfam PF07517 SecA DEAD-like domain 9 385 3.7E-101 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 SUPERFAMILY SSF81886 580 795 1.96E-40 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 Hamap MF_01382 Protein translocase subunit SecA [secA]. 1 784 15.502 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 Gene3D G3DSA:3.40.50.300 401 617 3.2E-31 T 28-03-2018 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 SMART SM00958 230 342 5.1E-36 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 Pfam PF01043 SecA preprotein cross-linking domain 235 342 2.7E-25 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 TIGRFAM TIGR03714 secA2: accessory Sec system translocase SecA2 9 771 0.0 T 28-03-2018 IPR022490 Protein translocase subunit SecA2 GO:0015031|GO:0015450 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 SUPERFAMILY SSF52540 401 563 2.85E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 Gene3D G3DSA:3.40.50.300 7 270 2.4E-44 T 28-03-2018 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 Gene3D G3DSA:3.40.50.300 326 400 0.049 T 28-03-2018 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 SMART SM00957 2 386 1.1E-195 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 PRINTS PR00906 SecA protein signature 360 377 6.6E-55 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 PRINTS PR00906 SecA protein signature 60 84 6.6E-55 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 PRINTS PR00906 SecA protein signature 172 192 6.6E-55 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 PRINTS PR00906 SecA protein signature 98 112 6.6E-55 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 PRINTS PR00906 SecA protein signature 114 124 6.6E-55 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 PRINTS PR00906 SecA protein signature 397 410 6.6E-55 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 PRINTS PR00906 SecA protein signature 323 345 6.6E-55 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 SUPERFAMILY SSF81767 233 351 7.85E-37 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 SUPERFAMILY SSF52540 8 229 1.77E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 SUPERFAMILY SSF52540 508 549 1.77E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS02990 e48d11fd6ad6ce4c72720f8126fba3e2 796 Gene3D G3DSA:1.10.3060.10 618 781 9.6E-19 T 28-03-2018 CWR44_RS01730 d7e1ae0f57811fe5166088af4b839503 233 Pfam PF04172 LrgB-like family 17 230 8.3E-65 T 28-03-2018 IPR007300 CidB/LrgB family CWR44_RS01730 d7e1ae0f57811fe5166088af4b839503 233 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 4 233 29.891 T 28-03-2018 IPR024891 Antiholin-like protein LrgB CWR44_RS03560 210a218a5f2c56caaf46443d7e392908 53 SUPERFAMILY SSF51735 3 49 2.08E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS03560 210a218a5f2c56caaf46443d7e392908 53 Pfam PF07993 Male sterility protein 7 40 2.8E-6 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CWR44_RS03560 210a218a5f2c56caaf46443d7e392908 53 Gene3D G3DSA:3.40.50.720 2 53 6.3E-12 T 28-03-2018 CWR44_RS10415 0ea5ceeef9d2c0e434c5e1d836bbda7c 295 Gene3D G3DSA:1.10.150.130 1 112 2.2E-21 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR44_RS10415 0ea5ceeef9d2c0e434c5e1d836bbda7c 295 SUPERFAMILY SSF56349 3 289 1.82E-61 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR44_RS10415 0ea5ceeef9d2c0e434c5e1d836bbda7c 295 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 295 57.322 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CWR44_RS10415 0ea5ceeef9d2c0e434c5e1d836bbda7c 295 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 88 3.5E-24 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWR44_RS10415 0ea5ceeef9d2c0e434c5e1d836bbda7c 295 Gene3D G3DSA:1.10.443.10 113 289 2.0E-48 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS10415 0ea5ceeef9d2c0e434c5e1d836bbda7c 295 Pfam PF00589 Phage integrase family 110 281 2.0E-51 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS10415 0ea5ceeef9d2c0e434c5e1d836bbda7c 295 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 6 295 1.1E-117 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CWR44_RS10415 0ea5ceeef9d2c0e434c5e1d836bbda7c 295 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 295 60.033 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CWR44_RS01120 13ff504d978c6d0ec51cbf088d7746a6 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 177 4.6E-39 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS01120 13ff504d978c6d0ec51cbf088d7746a6 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 4 177 1.0E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS01120 13ff504d978c6d0ec51cbf088d7746a6 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.3E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS01120 13ff504d978c6d0ec51cbf088d7746a6 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 92 105 1.3E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS01120 13ff504d978c6d0ec51cbf088d7746a6 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 161 1.3E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS01120 13ff504d978c6d0ec51cbf088d7746a6 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 123 139 1.3E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS01120 13ff504d978c6d0ec51cbf088d7746a6 214 SUPERFAMILY SSF56784 1 191 1.87E-47 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS01120 13ff504d978c6d0ec51cbf088d7746a6 214 Gene3D G3DSA:3.40.50.1000 1 202 1.4E-36 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS09350 f6c2965587aae7ef69bd524177b882a2 267 SUPERFAMILY SSF56784 1 267 3.92E-68 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS09350 f6c2965587aae7ef69bd524177b882a2 267 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 263 1.4E-58 T 28-03-2018 IPR000150 Cof family GO:0016787 CWR44_RS09350 f6c2965587aae7ef69bd524177b882a2 267 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 262 7.8E-64 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS09350 f6c2965587aae7ef69bd524177b882a2 267 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 236 8.8E-24 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR44_RS09350 f6c2965587aae7ef69bd524177b882a2 267 Gene3D G3DSA:3.40.50.1000 1 267 3.3E-45 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS03320 5f59697cf199ae5fd727cf058620abd0 340 Pfam PF03099 Biotin/lipoate A/B protein ligase family 53 160 2.6E-8 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWR44_RS03320 5f59697cf199ae5fd727cf058620abd0 340 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 16 331 4.3E-71 T 28-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CWR44_RS03320 5f59697cf199ae5fd727cf058620abd0 340 Gene3D G3DSA:3.30.930.10 9 254 3.0E-51 T 28-03-2018 CWR44_RS03320 5f59697cf199ae5fd727cf058620abd0 340 Gene3D G3DSA:3.30.390.50 255 340 1.3E-23 T 28-03-2018 CWR44_RS03320 5f59697cf199ae5fd727cf058620abd0 340 SUPERFAMILY SSF55681 7 251 3.56E-64 T 28-03-2018 CWR44_RS03320 5f59697cf199ae5fd727cf058620abd0 340 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 254 338 8.2E-26 T 28-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CWR44_RS03320 5f59697cf199ae5fd727cf058620abd0 340 SUPERFAMILY SSF82649 253 339 3.35E-24 T 28-03-2018 CWR44_RS05515 43b24173cef6635821d191683a4231cc 184 SUPERFAMILY SSF52317 2 181 5.35E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS05515 43b24173cef6635821d191683a4231cc 184 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 181 35.664 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CWR44_RS05515 43b24173cef6635821d191683a4231cc 184 ProSitePatterns PS01236 PdxT/SNO family family signature. 40 50 - T 28-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CWR44_RS05515 43b24173cef6635821d191683a4231cc 184 PIRSF PIRSF005639 1 184 1.1E-68 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CWR44_RS05515 43b24173cef6635821d191683a4231cc 184 Pfam PF01174 SNO glutamine amidotransferase family 5 184 2.3E-69 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CWR44_RS05515 43b24173cef6635821d191683a4231cc 184 Gene3D G3DSA:3.40.50.880 1 184 1.5E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS05515 43b24173cef6635821d191683a4231cc 184 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 180 2.8E-84 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 Gene3D G3DSA:3.30.870.10 506 691 5.7E-35 T 28-03-2018 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 Pfam PF02503 Polyphosphate kinase middle domain 134 328 1.7E-58 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 15 682 4.3E-274 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 PIRSF PIRSF015589 1 699 4.8E-264 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 Gene3D G3DSA:1.20.58.310 18 120 2.9E-38 T 28-03-2018 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 Pfam PF13090 Polyphosphate kinase C-terminal domain 341 682 6.3E-152 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 Gene3D G3DSA:3.30.1840.10 121 310 5.9E-59 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 SUPERFAMILY SSF56024 506 686 1.97E-70 T 28-03-2018 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 SUPERFAMILY SSF140356 13 118 1.83E-39 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 Gene3D G3DSA:3.30.870.10 326 505 6.5E-22 T 28-03-2018 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 Pfam PF13089 Polyphosphate kinase N-terminal domain 16 121 1.3E-39 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 Hamap MF_00347 Polyphosphate kinase [ppk]. 14 686 29.003 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 SUPERFAMILY SSF56024 328 502 7.06E-55 T 28-03-2018 CWR44_RS01850 d896c5ff5370374e6a6fc8631c4e303e 721 SUPERFAMILY SSF143724 119 315 7.85E-53 T 28-03-2018 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 579 1.4E-41 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 Pfam PF00890 FAD binding domain 6 392 5.2E-84 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 Gene3D G3DSA:4.10.80.40 548 579 2.5E-5 T 28-03-2018 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 PIRSF PIRSF000171 341 576 2.8E-15 T 28-03-2018 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 PIRSF PIRSF000171 1 240 2.6E-20 T 28-03-2018 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 Gene3D G3DSA:1.20.58.100 446 547 2.4E-25 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 SUPERFAMILY SSF56425 231 353 2.39E-31 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 SUPERFAMILY SSF51905 3 247 4.91E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 SUPERFAMILY SSF51905 357 425 4.91E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 SUPERFAMILY SSF46977 444 579 3.66E-44 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 Gene3D G3DSA:3.50.50.60 2 445 8.2E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 5.3E-6 T 28-03-2018 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 5.3E-6 T 28-03-2018 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.1E-8 T 28-03-2018 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 6.1E-8 T 28-03-2018 CWR44_RS08220 7e2e9734f95858a13d7fd7b6b1c63ff4 588 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 579 1.5E-285 T 28-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 CWR44_RS01225 c0e9bb7939a9d06a5ad4f65defa120e7 315 Gene3D G3DSA:1.20.58.340 248 315 1.3E-22 T 28-03-2018 CWR44_RS01225 c0e9bb7939a9d06a5ad4f65defa120e7 315 SUPERFAMILY SSF143865 3 247 1.14E-45 T 28-03-2018 CWR44_RS01225 c0e9bb7939a9d06a5ad4f65defa120e7 315 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 14 315 8.3E-69 T 28-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CWR44_RS01225 c0e9bb7939a9d06a5ad4f65defa120e7 315 SUPERFAMILY SSF144083 250 313 1.26E-22 T 28-03-2018 CWR44_RS01225 c0e9bb7939a9d06a5ad4f65defa120e7 315 Gene3D G3DSA:3.30.460.20 1 123 1.3E-14 T 28-03-2018 CWR44_RS01225 c0e9bb7939a9d06a5ad4f65defa120e7 315 Gene3D G3DSA:1.20.58.340 124 247 8.3E-16 T 28-03-2018 CWR44_RS01225 c0e9bb7939a9d06a5ad4f65defa120e7 315 Pfam PF01544 CorA-like Mg2+ transporter protein 27 311 3.2E-70 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CWR44_RS04020 3a5236a179a1d3aa9280debd70abc5b7 115 Pfam PF13411 MerR HTH family regulatory protein 6 68 3.4E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS04020 3a5236a179a1d3aa9280debd70abc5b7 115 SUPERFAMILY SSF46955 3 109 7.33E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain CWR44_RS04020 3a5236a179a1d3aa9280debd70abc5b7 115 Gene3D G3DSA:1.10.1660.10 59 115 1.0E-6 T 28-03-2018 CWR44_RS04020 3a5236a179a1d3aa9280debd70abc5b7 115 SMART SM00422 4 73 8.5E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS04020 3a5236a179a1d3aa9280debd70abc5b7 115 Gene3D G3DSA:1.10.1660.10 1 58 4.4E-16 T 28-03-2018 CWR44_RS03195 badbc27289f5a88a265872b7238d5455 210 SUPERFAMILY SSF52540 2 207 2.72E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03195 badbc27289f5a88a265872b7238d5455 210 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS03195 badbc27289f5a88a265872b7238d5455 210 SMART SM00382 26 208 3.8E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03195 badbc27289f5a88a265872b7238d5455 210 Gene3D G3DSA:3.40.50.300 1 209 9.1E-48 T 28-03-2018 CWR44_RS03195 badbc27289f5a88a265872b7238d5455 210 Pfam PF00005 ABC transporter 18 164 5.7E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS08925 da13c97a74d4f6e008e4d308efe198e7 332 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 296 1.4E-97 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CWR44_RS08925 da13c97a74d4f6e008e4d308efe198e7 332 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 305 28.776 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CWR44_RS08925 da13c97a74d4f6e008e4d308efe198e7 332 Pfam PF01715 IPP transferase 42 289 4.7E-80 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CWR44_RS08925 da13c97a74d4f6e008e4d308efe198e7 332 SUPERFAMILY SSF52540 9 137 2.66E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08925 da13c97a74d4f6e008e4d308efe198e7 332 SUPERFAMILY SSF52540 166 281 3.28E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08925 da13c97a74d4f6e008e4d308efe198e7 332 SUPERFAMILY SSF52540 7 50 3.28E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08925 da13c97a74d4f6e008e4d308efe198e7 332 Gene3D G3DSA:3.40.50.300 5 204 1.0E-66 T 28-03-2018 CWR44_RS08925 da13c97a74d4f6e008e4d308efe198e7 332 Gene3D G3DSA:1.10.287.890 206 286 1.6E-27 T 28-03-2018 CWR44_RS10460 9e716b732070f047397cf0ed73d671c0 287 Gene3D G3DSA:3.20.80.10 134 282 3.5E-15 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CWR44_RS10460 9e716b732070f047397cf0ed73d671c0 287 Gene3D G3DSA:1.10.10.60 4 61 4.5E-10 T 28-03-2018 CWR44_RS10460 9e716b732070f047397cf0ed73d671c0 287 Pfam PF14526 Integron-associated effector binding protein 132 280 1.7E-17 T 28-03-2018 IPR029441 Integron-associated effector binding protein CWR44_RS10460 9e716b732070f047397cf0ed73d671c0 287 SMART SM00342 21 104 1.0E-11 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS10460 9e716b732070f047397cf0ed73d671c0 287 Pfam PF12833 Helix-turn-helix domain 27 102 2.2E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS10460 9e716b732070f047397cf0ed73d671c0 287 Gene3D G3DSA:1.10.10.60 62 133 4.4E-6 T 28-03-2018 CWR44_RS10460 9e716b732070f047397cf0ed73d671c0 287 SUPERFAMILY SSF46689 5 54 3.18E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS10460 9e716b732070f047397cf0ed73d671c0 287 SMART SM00871 128 281 3.9E-9 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CWR44_RS10460 9e716b732070f047397cf0ed73d671c0 287 SUPERFAMILY SSF55136 169 282 2.25E-13 T 28-03-2018 CWR44_RS06530 3f33a39293db83253b2be7151a75e8c5 306 PIRSF PIRSF000535 1 303 1.4E-90 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWR44_RS06530 3f33a39293db83253b2be7151a75e8c5 306 Gene3D G3DSA:3.40.1190.20 43 304 3.8E-45 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS06530 3f33a39293db83253b2be7151a75e8c5 306 Gene3D G3DSA:2.20.150.10 9 42 9.0E-15 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CWR44_RS06530 3f33a39293db83253b2be7151a75e8c5 306 Pfam PF00294 pfkB family carbohydrate kinase 11 280 7.7E-57 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CWR44_RS06530 3f33a39293db83253b2be7151a75e8c5 306 SUPERFAMILY SSF53613 1 284 1.87E-66 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS06530 3f33a39293db83253b2be7151a75e8c5 306 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR44_RS06530 3f33a39293db83253b2be7151a75e8c5 306 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR44_RS06530 3f33a39293db83253b2be7151a75e8c5 306 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 1.1E-113 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CWR44_RS06530 3f33a39293db83253b2be7151a75e8c5 306 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 9.3E-115 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CWR44_RS02610 def6a63c2a736077f339cd6202e461f9 203 Gene3D G3DSA:3.30.160.110 119 145 1.2E-9 T 28-03-2018 CWR44_RS02610 def6a63c2a736077f339cd6202e461f9 203 SUPERFAMILY SSF51735 1 99 1.46E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02610 def6a63c2a736077f339cd6202e461f9 203 Gene3D G3DSA:3.40.50.720 3 118 1.6E-21 T 28-03-2018 CWR44_RS02610 def6a63c2a736077f339cd6202e461f9 203 SUPERFAMILY SSF75615 108 200 4.58E-21 T 28-03-2018 CWR44_RS02610 def6a63c2a736077f339cd6202e461f9 203 Pfam PF13241 Putative NAD(P)-binding 6 114 5.1E-24 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR44_RS02610 def6a63c2a736077f339cd6202e461f9 203 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 167 5.8E-30 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR44_RS02610 def6a63c2a736077f339cd6202e461f9 203 Pfam PF14824 Sirohaem biosynthesis protein central 118 138 3.6E-6 T 28-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR44_RS08665 04e41fb250dea2d59dacaa2030b36d09 435 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 5 434 36.255 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CWR44_RS08665 04e41fb250dea2d59dacaa2030b36d09 435 Pfam PF01134 Glucose inhibited division protein A 5 365 3.1E-111 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CWR44_RS08665 04e41fb250dea2d59dacaa2030b36d09 435 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 3 434 4.5E-220 T 28-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CWR44_RS08665 04e41fb250dea2d59dacaa2030b36d09 435 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 336 359 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CWR44_RS08665 04e41fb250dea2d59dacaa2030b36d09 435 SUPERFAMILY SSF51905 4 365 1.04E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS08665 04e41fb250dea2d59dacaa2030b36d09 435 Gene3D G3DSA:3.50.50.60 1 374 2.3E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS06640 070ff0c91b17958512d49f0c75eb5327 504 Gene3D G3DSA:3.40.190.10 228 384 2.1E-34 T 28-03-2018 CWR44_RS06640 070ff0c91b17958512d49f0c75eb5327 504 Gene3D G3DSA:1.10.3720.10 2 208 5.3E-32 T 28-03-2018 CWR44_RS06640 070ff0c91b17958512d49f0c75eb5327 504 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 209 2.9E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS06640 070ff0c91b17958512d49f0c75eb5327 504 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 234 499 2.1E-61 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CWR44_RS06640 070ff0c91b17958512d49f0c75eb5327 504 SUPERFAMILY SSF161098 13 199 1.09E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS06640 070ff0c91b17958512d49f0c75eb5327 504 SUPERFAMILY SSF53850 234 503 1.79E-70 T 28-03-2018 CWR44_RS06640 070ff0c91b17958512d49f0c75eb5327 504 Gene3D G3DSA:3.40.190.10 385 501 5.1E-24 T 28-03-2018 CWR44_RS11605 fdc0552fdd115096591c26f5f46fa727 273 SUPERFAMILY SSF56281 2 267 1.7E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS11605 fdc0552fdd115096591c26f5f46fa727 273 SMART SM00849 47 245 5.0E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS11605 fdc0552fdd115096591c26f5f46fa727 273 Gene3D G3DSA:3.60.15.10 1 263 2.2E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS11605 fdc0552fdd115096591c26f5f46fa727 273 Pfam PF00753 Metallo-beta-lactamase superfamily 51 211 3.2E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS03295 859470b24326cb18874d7523f1768b32 397 Gene3D G3DSA:3.20.20.70 2 381 7.7E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS03295 859470b24326cb18874d7523f1768b32 397 SUPERFAMILY SSF51395 6 346 3.1E-86 T 28-03-2018 CWR44_RS03295 859470b24326cb18874d7523f1768b32 397 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 345 2.0E-62 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CWR44_RS02630 99dbb0a57cb6f58d591d6fdd5d709757 243 Gene3D G3DSA:3.40.50.620 17 243 9.7E-53 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS02630 99dbb0a57cb6f58d591d6fdd5d709757 243 PIRSF PIRSF000857 8 243 2.1E-91 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CWR44_RS02630 99dbb0a57cb6f58d591d6fdd5d709757 243 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 49 237 4.7E-74 T 28-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CWR44_RS02630 99dbb0a57cb6f58d591d6fdd5d709757 243 SUPERFAMILY SSF52402 20 202 8.7E-53 T 28-03-2018 CWR44_RS02630 99dbb0a57cb6f58d591d6fdd5d709757 243 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 44 215 7.4E-52 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CWR44_RS02630 99dbb0a57cb6f58d591d6fdd5d709757 243 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 5 239 42.129 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CWR44_RS02630 99dbb0a57cb6f58d591d6fdd5d709757 243 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 30 238 3.6E-88 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CWR44_RS06010 0877b3970c314bbb289c906e980eadfd 285 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 241 275 1.0E-10 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CWR44_RS06010 0877b3970c314bbb289c906e980eadfd 285 PIRSF PIRSF006483 1 284 2.1E-68 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR44_RS06010 0877b3970c314bbb289c906e980eadfd 285 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 216 9.1E-51 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR44_RS03670 b57e386d9418166d4c16a9babb7407e0 272 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 260 37.492 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CWR44_RS03670 b57e386d9418166d4c16a9babb7407e0 272 PIRSF PIRSF000388 1 263 5.7E-95 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CWR44_RS03670 b57e386d9418166d4c16a9babb7407e0 272 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 5 261 4.9E-90 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CWR44_RS03670 b57e386d9418166d4c16a9babb7407e0 272 SUPERFAMILY SSF51621 3 260 2.55E-90 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR44_RS03670 b57e386d9418166d4c16a9babb7407e0 272 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 255 8.8E-96 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CWR44_RS03670 b57e386d9418166d4c16a9babb7407e0 272 Gene3D G3DSA:3.20.20.60 1 260 1.9E-70 T 28-03-2018 CWR44_RS03820 58e41681b71d42561fe505a7cecd1d15 390 Gene3D G3DSA:1.20.1250.20 196 387 3.4E-18 T 28-03-2018 CWR44_RS03820 58e41681b71d42561fe505a7cecd1d15 390 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 17 378 2.1E-71 T 28-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB CWR44_RS03820 58e41681b71d42561fe505a7cecd1d15 390 Gene3D G3DSA:1.20.1250.20 4 195 1.7E-17 T 28-03-2018 CWR44_RS03820 58e41681b71d42561fe505a7cecd1d15 390 SUPERFAMILY SSF103473 9 386 7.59E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS02325 590a57447da32d34eba141a6df2321f8 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 61 4.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS02325 590a57447da32d34eba141a6df2321f8 188 SUPERFAMILY SSF46689 8 67 7.98E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS02325 590a57447da32d34eba141a6df2321f8 188 Gene3D G3DSA:1.10.10.60 11 51 2.3E-11 T 28-03-2018 CWR44_RS02325 590a57447da32d34eba141a6df2321f8 188 Gene3D G3DSA:1.10.10.60 52 170 8.6E-7 T 28-03-2018 CWR44_RS11200 fdb4e1c209503dfad7fe44befa3d18ce 427 SUPERFAMILY SSF53383 2 425 3.09E-128 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS11200 fdb4e1c209503dfad7fe44befa3d18ce 427 Gene3D G3DSA:3.90.1150.10 315 427 1.7E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS11200 fdb4e1c209503dfad7fe44befa3d18ce 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS11200 fdb4e1c209503dfad7fe44befa3d18ce 427 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 426 100.443 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CWR44_RS11200 fdb4e1c209503dfad7fe44befa3d18ce 427 Pfam PF00202 Aminotransferase class-III 33 396 1.6E-76 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CWR44_RS11200 fdb4e1c209503dfad7fe44befa3d18ce 427 Gene3D G3DSA:3.90.1150.10 2 168 1.7E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS11200 fdb4e1c209503dfad7fe44befa3d18ce 427 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 424 1.6E-191 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CWR44_RS11200 fdb4e1c209503dfad7fe44befa3d18ce 427 Gene3D G3DSA:3.40.640.10 169 314 5.6E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS12175 d47c376c7999d89aedb29470a9de8fb4 150 SUPERFAMILY SSF46785 14 143 3.2E-41 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12175 d47c376c7999d89aedb29470a9de8fb4 150 Gene3D G3DSA:1.10.10.10 2 94 6.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12175 d47c376c7999d89aedb29470a9de8fb4 150 Pfam PF01475 Ferric uptake regulator family 22 139 1.7E-39 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CWR44_RS01095 5f6f1bdca22c9f04fb02b67c557b818e 290 SUPERFAMILY SSF53697 108 280 9.71E-33 T 28-03-2018 CWR44_RS01095 5f6f1bdca22c9f04fb02b67c557b818e 290 Pfam PF01380 SIS domain 126 254 1.7E-20 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR44_RS01095 5f6f1bdca22c9f04fb02b67c557b818e 290 Gene3D G3DSA:3.40.50.10490 119 275 3.9E-22 T 28-03-2018 CWR44_RS01095 5f6f1bdca22c9f04fb02b67c557b818e 290 SUPERFAMILY SSF46689 1 78 1.04E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS01095 5f6f1bdca22c9f04fb02b67c557b818e 290 Gene3D G3DSA:1.10.10.10 1 118 1.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01095 5f6f1bdca22c9f04fb02b67c557b818e 290 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 73 1.3E-14 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR44_RS00790 7b5821f083a57af2f0592ae93c71cc3d 207 Gene3D G3DSA:3.40.1370.10 2 144 4.6E-56 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CWR44_RS00790 7b5821f083a57af2f0592ae93c71cc3d 207 Gene3D G3DSA:3.40.1370.10 145 205 1.8E-16 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CWR44_RS00790 7b5821f083a57af2f0592ae93c71cc3d 207 SUPERFAMILY SSF52166 1 206 2.88E-81 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CWR44_RS00790 7b5821f083a57af2f0592ae93c71cc3d 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 8.3E-81 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00790 7b5821f083a57af2f0592ae93c71cc3d 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 36.435 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00790 7b5821f083a57af2f0592ae93c71cc3d 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 5.8E-71 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CWR44_RS03260 7412a2a689553e21fa0e871fb31f03ed 540 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 50 497 3.4E-142 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CWR44_RS03260 7412a2a689553e21fa0e871fb31f03ed 540 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 13 497 2.5E-178 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 PIRSF PIRSF000097 1 274 3.5E-90 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 SUPERFAMILY SSF51430 6 270 1.57E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 231 246 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 Pfam PF00248 Aldo/keto reductase family 14 263 2.5E-45 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 Gene3D G3DSA:3.20.20.100 1 277 4.7E-92 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 PRINTS PR00069 Aldo-keto reductase signature 35 59 1.4E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 PRINTS PR00069 Aldo-keto reductase signature 95 113 1.4E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 PRINTS PR00069 Aldo-keto reductase signature 127 144 1.4E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 PRINTS PR00069 Aldo-keto reductase signature 161 190 1.4E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS11795 5b2cb33f627c326b75d4d7f7ea9e71f4 278 PRINTS PR00069 Aldo-keto reductase signature 198 222 1.4E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS10650 3cb6639d3afcebb7b9ea3fbe1ee736ae 208 SMART SM00849 12 190 4.6E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS10650 3cb6639d3afcebb7b9ea3fbe1ee736ae 208 Pfam PF00753 Metallo-beta-lactamase superfamily 9 190 3.1E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS10650 3cb6639d3afcebb7b9ea3fbe1ee736ae 208 Gene3D G3DSA:3.60.15.10 1 206 7.8E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS10650 3cb6639d3afcebb7b9ea3fbe1ee736ae 208 SUPERFAMILY SSF56281 3 200 4.85E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS01610 e5a7a92d8bf98d3a2fc248566203c05e 288 Pfam PF01545 Cation efflux family 15 206 1.4E-44 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR44_RS01610 e5a7a92d8bf98d3a2fc248566203c05e 288 Gene3D G3DSA:1.20.1510.10 9 205 9.4E-34 T 28-03-2018 CWR44_RS01610 e5a7a92d8bf98d3a2fc248566203c05e 288 Pfam PF16916 Dimerisation domain of Zinc Transporter 212 285 8.5E-20 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR44_RS01610 e5a7a92d8bf98d3a2fc248566203c05e 288 SUPERFAMILY SSF160240 210 285 3.01E-19 T 28-03-2018 CWR44_RS01610 e5a7a92d8bf98d3a2fc248566203c05e 288 Gene3D G3DSA:3.30.70.1350 206 287 2.3E-19 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CWR44_RS01610 e5a7a92d8bf98d3a2fc248566203c05e 288 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 286 2.9E-62 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CWR44_RS01610 e5a7a92d8bf98d3a2fc248566203c05e 288 SUPERFAMILY SSF161111 7 208 1.83E-47 T 28-03-2018 CWR44_RS12470 0c8f245c94af3ec509d263b5b8c16f7e 186 Pfam PF00857 Isochorismatase family 5 178 2.6E-33 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CWR44_RS12470 0c8f245c94af3ec509d263b5b8c16f7e 186 Gene3D G3DSA:3.40.50.850 1 184 1.2E-42 T 28-03-2018 CWR44_RS12470 0c8f245c94af3ec509d263b5b8c16f7e 186 SUPERFAMILY SSF52499 2 183 4.32E-48 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CWR44_RS10890 23fb0d638deb83523f394b6783f72fe3 192 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 5 191 27.587 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CWR44_RS10890 23fb0d638deb83523f394b6783f72fe3 192 Gene3D G3DSA:3.40.50.620 2 192 1.9E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS10890 23fb0d638deb83523f394b6783f72fe3 192 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 9 190 6.3E-53 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CWR44_RS10890 23fb0d638deb83523f394b6783f72fe3 192 Pfam PF01467 Cytidylyltransferase-like 9 165 1.8E-25 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR44_RS10890 23fb0d638deb83523f394b6783f72fe3 192 SUPERFAMILY SSF52374 4 191 3.44E-44 T 28-03-2018 CWR44_RS10105 79cfb738ba2431e325cad57d671e1666 166 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 17 141 5.0E-54 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR44_RS10105 79cfb738ba2431e325cad57d671e1666 166 SUPERFAMILY SSF51261 8 160 1.24E-56 T 28-03-2018 IPR011055 Duplicated hybrid motif CWR44_RS10105 79cfb738ba2431e325cad57d671e1666 166 Gene3D G3DSA:2.70.70.10 5 165 1.3E-62 T 28-03-2018 CWR44_RS10105 79cfb738ba2431e325cad57d671e1666 166 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 18 138 7.7E-47 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR44_RS10105 79cfb738ba2431e325cad57d671e1666 166 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 80 92 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CWR44_RS01905 2a90d080fda0a58ae2d8112d312059fb 226 SMART SM00895 86 215 1.8E-10 T 28-03-2018 IPR011711 GntR, C-terminal CWR44_RS01905 2a90d080fda0a58ae2d8112d312059fb 226 Pfam PF07729 FCD domain 86 209 2.2E-16 T 28-03-2018 IPR011711 GntR, C-terminal CWR44_RS01905 2a90d080fda0a58ae2d8112d312059fb 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 73 1.6E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS01905 2a90d080fda0a58ae2d8112d312059fb 226 SUPERFAMILY SSF46785 10 85 1.15E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01905 2a90d080fda0a58ae2d8112d312059fb 226 SUPERFAMILY SSF48008 83 220 1.33E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR44_RS01905 2a90d080fda0a58ae2d8112d312059fb 226 SMART SM00345 19 77 4.3E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS01905 2a90d080fda0a58ae2d8112d312059fb 226 Gene3D G3DSA:1.20.120.530 72 224 1.1E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CWR44_RS01905 2a90d080fda0a58ae2d8112d312059fb 226 Gene3D G3DSA:1.10.10.10 12 71 3.3E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11220 5040b7c6fbf78577c36d26a13b414c01 270 Pfam PF01578 Cytochrome C assembly protein 67 266 2.9E-22 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CWR44_RS12715 cf174de1865254242056f3f4994ee333 153 SUPERFAMILY SSF52540 20 121 8.51E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS12715 cf174de1865254242056f3f4994ee333 153 Gene3D G3DSA:3.40.50.300 1 148 1.1E-46 T 28-03-2018 CWR44_RS12715 cf174de1865254242056f3f4994ee333 153 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 5 128 5.0E-36 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CWR44_RS12715 cf174de1865254242056f3f4994ee333 153 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 135 6.3E-40 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CWR44_RS00370 c6286862067facee5c3f844f363241b2 243 SUPERFAMILY SSF56300 1 234 4.34E-48 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS00370 c6286862067facee5c3f844f363241b2 243 PIRSF PIRSF000883 1 241 7.6E-41 T 28-03-2018 IPR011152 Phosphoesterase MJ0912 CWR44_RS00370 c6286862067facee5c3f844f363241b2 243 Gene3D G3DSA:3.60.21.10 1 242 1.1E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS00370 c6286862067facee5c3f844f363241b2 243 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 206 3.3E-25 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CWR44_RS08455 922dc5084f2a5e678e3202c3daae4204 207 SMART SM00072 5 188 6.8E-71 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CWR44_RS08455 922dc5084f2a5e678e3202c3daae4204 207 Gene3D G3DSA:3.40.50.300 1 52 8.6E-11 T 28-03-2018 CWR44_RS08455 922dc5084f2a5e678e3202c3daae4204 207 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 185 1.5E-72 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CWR44_RS08455 922dc5084f2a5e678e3202c3daae4204 207 SUPERFAMILY SSF52540 3 193 7.41E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08455 922dc5084f2a5e678e3202c3daae4204 207 Gene3D G3DSA:3.40.50.300 83 189 1.5E-35 T 28-03-2018 CWR44_RS08455 922dc5084f2a5e678e3202c3daae4204 207 Gene3D G3DSA:3.30.63.10 53 82 1.1E-24 T 28-03-2018 CWR44_RS08455 922dc5084f2a5e678e3202c3daae4204 207 Hamap MF_00328 Guanylate kinase [gmk]. 4 188 36.88 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CWR44_RS08455 922dc5084f2a5e678e3202c3daae4204 207 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CWR44_RS08455 922dc5084f2a5e678e3202c3daae4204 207 Pfam PF00625 Guanylate kinase 8 187 8.2E-52 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CWR44_RS03510 c6f26b3e145daa730ed00e036772abef 146 Pfam PF01047 MarR family 36 93 3.2E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS03510 c6f26b3e145daa730ed00e036772abef 146 Gene3D G3DSA:1.10.10.60 6 33 0.11 T 28-03-2018 CWR44_RS03510 c6f26b3e145daa730ed00e036772abef 146 SUPERFAMILY SSF46785 10 143 7.97E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03510 c6f26b3e145daa730ed00e036772abef 146 Gene3D G3DSA:1.10.10.10 34 146 1.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03510 c6f26b3e145daa730ed00e036772abef 146 SMART SM00347 29 129 8.7E-26 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS03510 c6f26b3e145daa730ed00e036772abef 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 2.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS03510 c6f26b3e145daa730ed00e036772abef 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 2.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS03510 c6f26b3e145daa730ed00e036772abef 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 2.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS04975 a24b6a314946c4a0e72c164d5f5321d2 451 Gene3D G3DSA:3.40.50.300 120 359 1.5E-21 T 28-03-2018 CWR44_RS04975 a24b6a314946c4a0e72c164d5f5321d2 451 SMART SM00885 31 152 2.0E-22 T 28-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CWR44_RS04975 a24b6a314946c4a0e72c164d5f5321d2 451 Pfam PF03288 Poxvirus D5 protein-like 357 438 1.2E-6 T 28-03-2018 IPR004968 DNA primase/nucleoside triphosphatase, C-terminal CWR44_RS04975 a24b6a314946c4a0e72c164d5f5321d2 451 SUPERFAMILY SSF52540 139 308 5.14E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04975 a24b6a314946c4a0e72c164d5f5321d2 451 Pfam PF08706 D5 N terminal like 56 150 3.7E-10 T 28-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CWR44_RS04975 a24b6a314946c4a0e72c164d5f5321d2 451 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 102 409 1.6E-64 T 28-03-2018 IPR006500 DNA primase, phage/plasmid CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 Pfam PF02824 TGS domain 4 63 1.9E-11 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 Pfam PF03129 Anticodon binding domain 547 632 2.6E-25 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 3.0E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 SUPERFAMILY SSF81271 4 63 5.45E-15 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 68 641 34.92 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 74 637 4.0E-237 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 Gene3D G3DSA:3.30.930.10 220 537 1.3E-105 T 28-03-2018 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 SUPERFAMILY SSF52954 536 639 3.47E-34 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 Gene3D G3DSA:3.30.980.10 67 146 1.8E-27 T 28-03-2018 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 Gene3D G3DSA:3.30.54.20 147 186 5.9E-21 T 28-03-2018 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 513 526 1.5E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 1.5E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 470 498 1.5E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 540 552 1.5E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 1.5E-45 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 SUPERFAMILY SSF55681 242 531 2.59E-94 T 28-03-2018 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 SUPERFAMILY SSF55186 66 239 5.1E-68 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 Gene3D G3DSA:3.10.20.30 1 64 3.0E-20 T 28-03-2018 IPR012675 Beta-grasp domain CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 Gene3D G3DSA:3.40.50.800 538 645 1.5E-30 T 28-03-2018 IPR004154 Anticodon-binding CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 SMART SM00863 169 218 1.9E-25 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWR44_RS11280 64175d89e27ce788af2295bc889d09a9 645 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 324 534 1.1E-32 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS00340 05727439f542afa6647786c218f7bc5b 457 SUPERFAMILY SSF52540 323 439 1.5E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00340 05727439f542afa6647786c218f7bc5b 457 SUPERFAMILY SSF88697 140 278 5.55E-22 T 28-03-2018 IPR015947 PUA-like domain CWR44_RS00340 05727439f542afa6647786c218f7bc5b 457 Gene3D G3DSA:3.40.50.300 310 455 8.7E-6 T 28-03-2018 CWR44_RS00340 05727439f542afa6647786c218f7bc5b 457 Gene3D G3DSA:3.10.590.10 141 289 2.6E-16 T 28-03-2018 CWR44_RS00340 05727439f542afa6647786c218f7bc5b 457 Gene3D G3DSA:3.10.590.10 4 140 5.3E-12 T 28-03-2018 CWR44_RS00340 05727439f542afa6647786c218f7bc5b 457 Pfam PF07728 AAA domain (dynein-related subfamily) 315 406 6.4E-5 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CWR44_RS00340 05727439f542afa6647786c218f7bc5b 457 SUPERFAMILY SSF88697 6 133 7.46E-15 T 28-03-2018 IPR015947 PUA-like domain CWR44_RS00340 05727439f542afa6647786c218f7bc5b 457 Pfam PF01878 EVE domain 173 270 6.1E-8 T 28-03-2018 IPR002740 EVE domain CWR44_RS00175 44fd9a0aa12bbc8eb30456337e0f8ba1 241 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 240 13.192 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00175 44fd9a0aa12bbc8eb30456337e0f8ba1 241 PRINTS PR00123 ATP synthase A subunit signature 220 235 6.7E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00175 44fd9a0aa12bbc8eb30456337e0f8ba1 241 PRINTS PR00123 ATP synthase A subunit signature 82 98 6.7E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00175 44fd9a0aa12bbc8eb30456337e0f8ba1 241 PRINTS PR00123 ATP synthase A subunit signature 167 189 6.7E-19 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00175 44fd9a0aa12bbc8eb30456337e0f8ba1 241 Pfam PF00119 ATP synthase A chain 25 234 1.5E-56 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00175 44fd9a0aa12bbc8eb30456337e0f8ba1 241 ProSitePatterns PS00449 ATP synthase a subunit signature. 170 179 - T 28-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00175 44fd9a0aa12bbc8eb30456337e0f8ba1 241 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 18 236 2.3E-43 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00175 44fd9a0aa12bbc8eb30456337e0f8ba1 241 Gene3D G3DSA:1.20.120.220 73 241 1.4E-39 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00175 44fd9a0aa12bbc8eb30456337e0f8ba1 241 SUPERFAMILY SSF81336 74 234 1.44E-37 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 ProSitePatterns PS01244 Aconitase family signature 2. 388 401 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 SUPERFAMILY SSF53732 1 454 2.88E-158 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 Gene3D G3DSA:3.30.499.10 313 456 4.6E-47 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 Gene3D G3DSA:3.30.499.10 1 153 7.3E-40 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 Pfam PF00330 Aconitase family (aconitate hydratase) 7 446 6.4E-149 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 ProSitePatterns PS00450 Aconitase family signature 1. 328 344 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 455 57.195 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 PRINTS PR00415 Aconitase family signature 107 115 1.1E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 PRINTS PR00415 Aconitase family signature 132 147 1.1E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 PRINTS PR00415 Aconitase family signature 208 221 1.1E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 PRINTS PR00415 Aconitase family signature 332 343 1.1E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 PRINTS PR00415 Aconitase family signature 194 207 1.1E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 PRINTS PR00415 Aconitase family signature 282 296 1.1E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 PRINTS PR00415 Aconitase family signature 388 401 1.1E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 PRINTS PR00415 Aconitase family signature 81 94 1.1E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 PRINTS PR00415 Aconitase family signature 118 131 1.1E-45 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 454 1.1E-215 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CWR44_RS12750 ec601d6a49cb9ef0761024043039fec5 456 Gene3D G3DSA:3.40.1060.10 154 284 2.7E-43 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CWR44_RS11480 a97eca9eec3889efd25b5885af7a01f4 386 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 186 206 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CWR44_RS11480 a97eca9eec3889efd25b5885af7a01f4 386 SUPERFAMILY SSF53383 7 365 2.94E-89 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS11480 a97eca9eec3889efd25b5885af7a01f4 386 Pfam PF00266 Aminotransferase class-V 23 333 5.4E-36 T 28-03-2018 IPR000192 Aminotransferase class V domain CWR44_RS11480 a97eca9eec3889efd25b5885af7a01f4 386 Gene3D G3DSA:3.90.1150.10 257 368 5.8E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS11480 a97eca9eec3889efd25b5885af7a01f4 386 PIRSF PIRSF000524 2 385 2.2E-116 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CWR44_RS11480 a97eca9eec3889efd25b5885af7a01f4 386 Gene3D G3DSA:3.40.640.10 17 256 1.6E-27 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS01625 3d24d9c2af7cb96b7894fe106b9c6b19 381 Gene3D G3DSA:3.90.1510.10 46 280 4.6E-93 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CWR44_RS01625 3d24d9c2af7cb96b7894fe106b9c6b19 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 5 379 1.2E-159 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR44_RS01625 3d24d9c2af7cb96b7894fe106b9c6b19 381 Pfam PF02595 Glycerate kinase family 6 378 5.3E-147 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR44_RS01625 3d24d9c2af7cb96b7894fe106b9c6b19 381 SUPERFAMILY SSF110738 5 379 5.23E-137 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR44_RS01625 3d24d9c2af7cb96b7894fe106b9c6b19 381 PIRSF PIRSF006078 4 380 4.9E-140 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CWR44_RS01570 316e752224e0bee2acba458c86370110 414 Gene3D G3DSA:3.40.630.30 1 167 9.2E-30 T 28-03-2018 CWR44_RS01570 316e752224e0bee2acba458c86370110 414 Gene3D G3DSA:3.40.630.30 168 389 4.0E-38 T 28-03-2018 CWR44_RS01570 316e752224e0bee2acba458c86370110 414 SUPERFAMILY SSF46589 244 308 1.31E-16 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CWR44_RS01570 316e752224e0bee2acba458c86370110 414 Pfam PF02388 FemAB family 6 413 2.3E-148 T 28-03-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 CWR44_RS01570 316e752224e0bee2acba458c86370110 414 SUPERFAMILY SSF55729 1 164 1.11E-57 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS01570 316e752224e0bee2acba458c86370110 414 SUPERFAMILY SSF55729 166 244 1.34E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS01570 316e752224e0bee2acba458c86370110 414 SUPERFAMILY SSF55729 309 408 1.34E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS07205 064cd96e65de4066cd0ba9174e3e1886 144 Pfam PF01934 Protein of unknown function DUF86 20 123 5.3E-17 T 28-03-2018 IPR008201 Protein of unknown function DUF86 CWR44_RS07205 064cd96e65de4066cd0ba9174e3e1886 144 Gene3D G3DSA:1.20.120.580 1 139 1.1E-29 T 28-03-2018 IPR008201 Protein of unknown function DUF86 CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 SMART SM01340 208 326 1.4E-54 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 1.1E-99 T 28-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 671 27.296 T 28-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 28-03-2018 IPR014762 DNA mismatch repair, conserved site CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 324 9.7E-38 T 28-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 SMART SM00853 489 631 3.4E-51 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 Gene3D G3DSA:3.30.230.10 213 325 4.9E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 119 1.9E-12 T 28-03-2018 CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 Pfam PF08676 MutL C terminal dimerisation domain 488 631 1.8E-46 T 28-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 Gene3D G3DSA:3.30.565.10 4 198 8.4E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 SUPERFAMILY SSF54211 190 326 2.05E-37 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 SUPERFAMILY SSF55874 3 213 8.12E-51 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS08895 244ff8e4bcc5f0e0709e47e928134484 675 SUPERFAMILY SSF118116 485 673 7.45E-54 T 28-03-2018 CWR44_RS05120 43e39fa8276885d86208c9e130c992d7 381 PIRSF PIRSF001434 1 381 5.6E-142 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS05120 43e39fa8276885d86208c9e130c992d7 381 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 188 202 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS05120 43e39fa8276885d86208c9e130c992d7 381 Gene3D G3DSA:3.40.640.10 1 246 5.0E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS05120 43e39fa8276885d86208c9e130c992d7 381 Gene3D G3DSA:3.90.1150.10 247 381 9.6E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS05120 43e39fa8276885d86208c9e130c992d7 381 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 377 2.5E-147 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS05120 43e39fa8276885d86208c9e130c992d7 381 SUPERFAMILY SSF53383 6 378 8.7E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS03440 b97d7b5e647e964654f18f72f200ad12 71 Pfam PF09855 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) 8 70 1.4E-28 T 28-03-2018 IPR018652 Protein of unknown function DUF2082, nucleic-acid-binding, Zn-ribbon CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 Gene3D G3DSA:3.40.50.1360 67 236 9.5E-38 T 28-03-2018 CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 4.5E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 Pfam PF00455 DeoR C terminal sensor domain 75 218 4.5E-45 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 Gene3D G3DSA:1.10.10.10 1 66 4.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 SMART SM00420 6 58 6.4E-19 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 SMART SM01134 73 231 6.1E-57 T 28-03-2018 CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 SUPERFAMILY SSF46785 4 79 1.95E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 SUPERFAMILY SSF100950 74 231 5.94E-33 T 28-03-2018 CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.2E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR44_RS06525 c0ca326af6e3a293aa336d01eddf7305 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.2E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR44_RS10275 4dd013685c27095a0f68f6b149578824 199 Pfam PF07187 Protein of unknown function (DUF1405) 28 185 1.4E-52 T 28-03-2018 IPR009845 Protein of unknown function DUF1405 CWR44_RS06240 034b676838e2aebf6389ad3e582683da 430 SUPERFAMILY SSF69189 316 383 9.81E-27 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR44_RS06240 034b676838e2aebf6389ad3e582683da 430 Gene3D G3DSA:3.40.710.10 33 314 2.0E-37 T 28-03-2018 CWR44_RS06240 034b676838e2aebf6389ad3e582683da 430 SUPERFAMILY SSF56601 1 315 8.78E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR44_RS06240 034b676838e2aebf6389ad3e582683da 430 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 131 148 7.3E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR44_RS06240 034b676838e2aebf6389ad3e582683da 430 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 74 85 7.3E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR44_RS06240 034b676838e2aebf6389ad3e582683da 430 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 158 171 7.3E-15 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR44_RS06240 034b676838e2aebf6389ad3e582683da 430 Gene3D G3DSA:2.30.140.20 315 381 2.7E-26 T 28-03-2018 IPR015294 Penicillin-binding protein 4, C-terminal domain CWR44_RS06240 034b676838e2aebf6389ad3e582683da 430 Pfam PF09211 Domain of unknown function (DUF1958) 317 381 5.8E-26 T 28-03-2018 IPR015294 Penicillin-binding protein 4, C-terminal domain CWR44_RS06240 034b676838e2aebf6389ad3e582683da 430 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 57 288 2.5E-54 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CWR44_RS09425 48fad5a9b3a97a4f2d89ae98f15a3e4a 110 SMART SM00530 6 61 7.4E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS09425 48fad5a9b3a97a4f2d89ae98f15a3e4a 110 Pfam PF01381 Helix-turn-helix 7 61 4.8E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS09425 48fad5a9b3a97a4f2d89ae98f15a3e4a 110 SUPERFAMILY SSF47413 1 68 1.64E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS09425 48fad5a9b3a97a4f2d89ae98f15a3e4a 110 Gene3D G3DSA:1.10.260.40 1 110 1.0E-19 T 28-03-2018 CWR44_RS04515 f7f553da250f96c6ed51a1208b15e3f2 252 Gene3D G3DSA:3.40.50.300 1 243 3.9E-65 T 28-03-2018 CWR44_RS04515 f7f553da250f96c6ed51a1208b15e3f2 252 SMART SM00382 31 219 6.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS04515 f7f553da250f96c6ed51a1208b15e3f2 252 Pfam PF00005 ABC transporter 22 170 2.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS04515 f7f553da250f96c6ed51a1208b15e3f2 252 SUPERFAMILY SSF52540 3 226 1.21E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03310 fad74fec20f87718891e69603cc50cc7 265 SMART SM00506 85 226 1.5E-27 T 28-03-2018 IPR002589 Macro domain CWR44_RS03310 fad74fec20f87718891e69603cc50cc7 265 SUPERFAMILY SSF52949 84 261 2.02E-53 T 28-03-2018 CWR44_RS03310 fad74fec20f87718891e69603cc50cc7 265 Gene3D G3DSA:3.40.220.10 13 264 7.7E-62 T 28-03-2018 CWR44_RS03310 fad74fec20f87718891e69603cc50cc7 265 Pfam PF01661 Macro domain 102 226 3.0E-37 T 28-03-2018 IPR002589 Macro domain CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 Pfam PF07085 DRTGG domain 75 177 5.4E-27 T 28-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 SUPERFAMILY SSF54637 324 428 1.22E-6 T 28-03-2018 IPR029069 HotDog domain CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 Gene3D G3DSA:3.40.1390.20 69 187 3.4E-26 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 Gene3D G3DSA:3.10.580.10 188 297 5.1E-23 T 28-03-2018 CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 Gene3D G3DSA:3.10.129.10 298 430 3.2E-13 T 28-03-2018 CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 SUPERFAMILY SSF75138 70 184 1.44E-27 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 SUPERFAMILY SSF54631 180 304 2.4E-26 T 28-03-2018 CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 SMART SM00116 258 305 0.036 T 28-03-2018 IPR000644 CBS domain CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 SMART SM00116 199 247 1.1 T 28-03-2018 IPR000644 CBS domain CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 Gene3D G3DSA:1.10.10.10 4 68 4.6E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 Pfam PF00571 CBS domain 219 244 3.2E-4 T 28-03-2018 IPR000644 CBS domain CWR44_RS11385 3779aed1fb73b5fe86588385e9c925d7 434 Pfam PF00571 CBS domain 252 304 1.2E-5 T 28-03-2018 IPR000644 CBS domain CWR44_RS03395 5b6c07a92c7e55be5803a18d03804471 1067 Gene3D G3DSA:2.130.10.10 409 1013 7.5E-16 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CWR44_RS03395 5b6c07a92c7e55be5803a18d03804471 1067 Pfam PF04650 YSIRK type signal peptide 8 33 3.6E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS03395 5b6c07a92c7e55be5803a18d03804471 1067 SUPERFAMILY SSF50969 407 648 1.8E-14 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CWR44_RS03395 5b6c07a92c7e55be5803a18d03804471 1067 SUPERFAMILY SSF50969 745 844 1.8E-14 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CWR44_RS03395 5b6c07a92c7e55be5803a18d03804471 1067 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 43 7.8E-15 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS04300 66d5be7c064f414d835e5354f6cb117c 129 SUPERFAMILY SSF53901 6 127 1.66E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS04300 66d5be7c064f414d835e5354f6cb117c 129 Gene3D G3DSA:3.40.47.10 2 60 3.2E-16 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CWR44_RS04300 66d5be7c064f414d835e5354f6cb117c 129 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 6 120 3.2E-13 T 28-03-2018 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: R-HSA-1989781 CWR44_RS09380 1751c16161cc7ad926d0015e3990408e 325 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 3 323 1.4E-202 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CWR44_RS09380 1751c16161cc7ad926d0015e3990408e 325 SUPERFAMILY SSF51412 3 314 4.71E-92 T 28-03-2018 CWR44_RS09380 1751c16161cc7ad926d0015e3990408e 325 SMART SM01240 2 325 5.5E-110 T 28-03-2018 CWR44_RS09380 1751c16161cc7ad926d0015e3990408e 325 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 164 176 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CWR44_RS09380 1751c16161cc7ad926d0015e3990408e 325 Hamap MF_01511 GMP reductase [guaC]. 1 324 63.755 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CWR44_RS09380 1751c16161cc7ad926d0015e3990408e 325 PIRSF PIRSF036500 1 325 6.3E-195 T 28-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CWR44_RS09380 1751c16161cc7ad926d0015e3990408e 325 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 5 309 2.2E-67 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CWR44_RS09380 1751c16161cc7ad926d0015e3990408e 325 Gene3D G3DSA:3.20.20.70 2 324 3.3E-67 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS07650 c55560a1045af7d922a8d05bb35c8907 33 Pfam PF07553 Host cell surface-exposed lipoprotein 4 31 2.5E-14 T 28-03-2018 IPR011434 Domain of unknown function DUF1535 CWR44_RS00195 f92a939616d8a52dea7bf4805d76f67b 412 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 412 53.494 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWR44_RS00195 f92a939616d8a52dea7bf4805d76f67b 412 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWR44_RS00195 f92a939616d8a52dea7bf4805d76f67b 412 Gene3D G3DSA:3.40.640.10 33 269 1.5E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS00195 f92a939616d8a52dea7bf4805d76f67b 412 Gene3D G3DSA:3.90.1150.10 270 411 3.4E-59 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS00195 f92a939616d8a52dea7bf4805d76f67b 412 SUPERFAMILY SSF53383 3 411 5.47E-178 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS00195 f92a939616d8a52dea7bf4805d76f67b 412 PIRSF PIRSF000412 1 411 2.9E-167 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CWR44_RS00195 f92a939616d8a52dea7bf4805d76f67b 412 Pfam PF00464 Serine hydroxymethyltransferase 4 381 6.5E-179 T 28-03-2018 CWR44_RS07350 a0c4a384e0289c27f1fb00ee13fb9ffd 375 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 340 2.0E-69 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CWR44_RS07350 a0c4a384e0289c27f1fb00ee13fb9ffd 375 Gene3D G3DSA:3.20.20.70 1 358 7.3E-87 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS07350 a0c4a384e0289c27f1fb00ee13fb9ffd 375 SUPERFAMILY SSF51395 1 348 4.28E-86 T 28-03-2018 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 128 2.2E-41 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 251 1.4E-41 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 SMART SM00480 18 372 1.1E-177 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 SUPERFAMILY SSF55979 136 251 1.41E-28 T 28-03-2018 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 Gene3D G3DSA:3.10.150.10 1 131 2.8E-27 T 28-03-2018 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 2 376 5.4E-113 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 PIRSF PIRSF000804 2 377 2.7E-111 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 SUPERFAMILY SSF55979 254 376 5.94E-32 T 28-03-2018 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 Gene3D G3DSA:3.10.150.10 257 377 1.3E-26 T 28-03-2018 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 Gene3D G3DSA:3.10.150.10 132 255 7.0E-35 T 28-03-2018 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 375 6.5E-38 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS04440 06e47a4f7f14c2c740b598c895e2dd80 377 SUPERFAMILY SSF55979 2 128 8.5E-24 T 28-03-2018 CWR44_RS05305 f999ea602abd0b216e987e1bdc2a7e18 282 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 2 278 34.215 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CWR44_RS05305 f999ea602abd0b216e987e1bdc2a7e18 282 Gene3D G3DSA:3.30.70.890 160 281 7.2E-27 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS05305 f999ea602abd0b216e987e1bdc2a7e18 282 Pfam PF00288 GHMP kinases N terminal domain 86 141 5.8E-10 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWR44_RS05305 f999ea602abd0b216e987e1bdc2a7e18 282 Pfam PF08544 GHMP kinases C terminal 198 269 5.2E-13 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS05305 f999ea602abd0b216e987e1bdc2a7e18 282 Gene3D G3DSA:3.30.230.10 3 158 2.2E-45 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS05305 f999ea602abd0b216e987e1bdc2a7e18 282 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 4 282 2.6E-89 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CWR44_RS05305 f999ea602abd0b216e987e1bdc2a7e18 282 PIRSF PIRSF010376 1 281 2.4E-93 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CWR44_RS05305 f999ea602abd0b216e987e1bdc2a7e18 282 SUPERFAMILY SSF54211 1 156 4.4E-43 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS05305 f999ea602abd0b216e987e1bdc2a7e18 282 SUPERFAMILY SSF55060 160 280 2.4E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS08655 4de54721a29fb9b3cf78f6eb3cf76c8b 288 Pfam PF02481 DNA recombination-mediator protein A 72 278 3.5E-68 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CWR44_RS08655 4de54721a29fb9b3cf78f6eb3cf76c8b 288 SUPERFAMILY SSF102405 80 284 3.66E-28 T 28-03-2018 CWR44_RS08655 4de54721a29fb9b3cf78f6eb3cf76c8b 288 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 70 284 1.2E-64 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CWR44_RS08655 4de54721a29fb9b3cf78f6eb3cf76c8b 288 Gene3D G3DSA:3.40.50.450 112 263 7.4E-33 T 28-03-2018 CWR44_RS04380 5950c6945287bc2e400e5ec6c9467b38 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 5.3E-28 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CWR44_RS04380 5950c6945287bc2e400e5ec6c9467b38 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 3.8E-22 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04380 5950c6945287bc2e400e5ec6c9467b38 148 Gene3D G3DSA:3.40.5.10 1 49 5.2E-24 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04380 5950c6945287bc2e400e5ec6c9467b38 148 SUPERFAMILY SSF55653 58 147 2.75E-25 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CWR44_RS04380 5950c6945287bc2e400e5ec6c9467b38 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 5.6E-43 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS04380 5950c6945287bc2e400e5ec6c9467b38 148 Gene3D G3DSA:3.10.430.100 63 147 1.9E-28 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CWR44_RS04380 5950c6945287bc2e400e5ec6c9467b38 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 24.055 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS04380 5950c6945287bc2e400e5ec6c9467b38 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04380 5950c6945287bc2e400e5ec6c9467b38 148 SUPERFAMILY SSF55658 1 56 1.74E-17 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CWR44_RS11490 9c5841786dcf9019e657578bf37e1111 374 Gene3D G3DSA:3.40.50.1000 1 171 0.022 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS11490 9c5841786dcf9019e657578bf37e1111 374 Gene3D G3DSA:3.40.50.1000 205 374 8.0E-24 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS11490 9c5841786dcf9019e657578bf37e1111 374 SUPERFAMILY SSF56784 1 373 2.53E-53 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS11490 9c5841786dcf9019e657578bf37e1111 374 Pfam PF13242 HAD-hyrolase-like 282 366 1.2E-13 T 28-03-2018 CWR44_RS05945 81ccfdff439cc08c0218c134db3e2573 327 Gene3D G3DSA:3.30.70.890 174 326 1.0E-44 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS05945 81ccfdff439cc08c0218c134db3e2573 327 SUPERFAMILY SSF54211 5 165 1.37E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS05945 81ccfdff439cc08c0218c134db3e2573 327 Pfam PF08544 GHMP kinases C terminal 221 308 6.6E-6 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS05945 81ccfdff439cc08c0218c134db3e2573 327 SUPERFAMILY SSF55060 175 310 1.1E-43 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CWR44_RS05945 81ccfdff439cc08c0218c134db3e2573 327 PIRSF PIRSF015950 2 327 4.2E-121 T 28-03-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 CWR44_RS05945 81ccfdff439cc08c0218c134db3e2573 327 Gene3D G3DSA:3.30.230.10 2 173 7.5E-60 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS05945 81ccfdff439cc08c0218c134db3e2573 327 Pfam PF00288 GHMP kinases N terminal domain 92 149 3.2E-6 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CWR44_RS05945 81ccfdff439cc08c0218c134db3e2573 327 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 6 308 3.9E-122 T 28-03-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 CWR44_RS09415 773cab98e8b602daaac6fd17a455d5b0 366 Pfam PF14657 Arm DNA-binding domain 11 51 5.9E-12 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CWR44_RS09415 773cab98e8b602daaac6fd17a455d5b0 366 Gene3D G3DSA:1.10.443.10 167 353 3.2E-38 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS09415 773cab98e8b602daaac6fd17a455d5b0 366 SUPERFAMILY SSF56349 60 352 6.77E-66 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR44_RS09415 773cab98e8b602daaac6fd17a455d5b0 366 Pfam PF00589 Phage integrase family 172 344 1.7E-28 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS09415 773cab98e8b602daaac6fd17a455d5b0 366 Gene3D G3DSA:1.10.150.130 50 166 1.5E-19 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR44_RS09415 773cab98e8b602daaac6fd17a455d5b0 366 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 61 116 1.6E-12 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWR44_RS06330 b0c4cabddb92dcc54f1ca61f40812b66 344 Gene3D G3DSA:3.30.565.10 138 330 1.1E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS06330 b0c4cabddb92dcc54f1ca61f40812b66 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 310 4.4E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS06330 b0c4cabddb92dcc54f1ca61f40812b66 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 258 272 4.4E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS06330 b0c4cabddb92dcc54f1ca61f40812b66 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 276 286 4.4E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS06330 b0c4cabddb92dcc54f1ca61f40812b66 344 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 329 4.4E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS06330 b0c4cabddb92dcc54f1ca61f40812b66 344 SMART SM00387 222 332 2.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS06330 b0c4cabddb92dcc54f1ca61f40812b66 344 SUPERFAMILY SSF47384 111 177 9.42E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS06330 b0c4cabddb92dcc54f1ca61f40812b66 344 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 223 331 1.5E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS06330 b0c4cabddb92dcc54f1ca61f40812b66 344 SUPERFAMILY SSF55874 168 330 2.1E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS07860 0ed0b299db6881b5c764776a7c6584df 343 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 161 4.0E-16 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWR44_RS07860 0ed0b299db6881b5c764776a7c6584df 343 SUPERFAMILY SSF56042 168 337 1.5E-55 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR44_RS07860 0ed0b299db6881b5c764776a7c6584df 343 Gene3D G3DSA:3.30.1330.10 27 158 2.7E-52 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWR44_RS07860 0ed0b299db6881b5c764776a7c6584df 343 SUPERFAMILY SSF55326 4 166 1.0E-48 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CWR44_RS07860 0ed0b299db6881b5c764776a7c6584df 343 Gene3D G3DSA:3.90.650.10 168 341 1.1E-59 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR44_RS07860 0ed0b299db6881b5c764776a7c6584df 343 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 335 1.7E-31 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CWR44_RS07860 0ed0b299db6881b5c764776a7c6584df 343 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 342 44.835 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR44_RS07860 0ed0b299db6881b5c764776a7c6584df 343 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 331 3.6E-130 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CWR44_RS01130 fe4ae7532903a862c1c65e867f69f156 533 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 446 512 1.6E-13 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS01130 fe4ae7532903a862c1c65e867f69f156 533 Gene3D G3DSA:3.30.1360.60 449 526 1.9E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS01130 fe4ae7532903a862c1c65e867f69f156 533 Pfam PF00367 phosphotransferase system, EIIB 455 485 9.8E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS01130 fe4ae7532903a862c1c65e867f69f156 533 TIGRFAM TIGR02005 PTS-IIBC-alpha: PTS system, alpha-glucoside-specific IIBC component 1 526 1.6E-271 T 28-03-2018 IPR010975 Phosphotransferase system, alpha-glucoside-specific IIBC component GO:0008982|GO:0009401 CWR44_RS01130 fe4ae7532903a862c1c65e867f69f156 533 Pfam PF02378 Phosphotransferase system, EIIC 9 343 4.6E-67 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS01130 fe4ae7532903a862c1c65e867f69f156 533 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 464 481 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS01130 fe4ae7532903a862c1c65e867f69f156 533 SUPERFAMILY SSF55604 452 525 2.09E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS00635 8b962f8394aa9092e846ad973dec9b22 145 PIRSF PIRSF002181 1 143 1.0E-47 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00635 8b962f8394aa9092e846ad973dec9b22 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 26.889 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00635 8b962f8394aa9092e846ad973dec9b22 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CWR44_RS00635 8b962f8394aa9092e846ad973dec9b22 145 Pfam PF00572 Ribosomal protein L13 15 139 1.5E-52 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00635 8b962f8394aa9092e846ad973dec9b22 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 2.1E-60 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00635 8b962f8394aa9092e846ad973dec9b22 145 SUPERFAMILY SSF52161 5 143 3.27E-55 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00635 8b962f8394aa9092e846ad973dec9b22 145 Gene3D G3DSA:3.90.1180.10 1 145 1.4E-57 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CWR44_RS10120 28112b948e8bd96ec658c9d13474073f 281 Gene3D G3DSA:3.40.50.10170 1 151 2.2E-51 T 28-03-2018 CWR44_RS10120 28112b948e8bd96ec658c9d13474073f 281 Gene3D G3DSA:3.30.1180.10 152 281 8.1E-31 T 28-03-2018 CWR44_RS10120 28112b948e8bd96ec658c9d13474073f 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 6 278 3.7E-83 T 28-03-2018 IPR003797 DegV CWR44_RS10120 28112b948e8bd96ec658c9d13474073f 281 SUPERFAMILY SSF82549 3 279 1.1E-86 T 28-03-2018 CWR44_RS10120 28112b948e8bd96ec658c9d13474073f 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 6 276 4.1E-95 T 28-03-2018 IPR003797 DegV CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 SUPERFAMILY SSF53784 1 311 9.55E-112 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 Gene3D G3DSA:3.40.50.450 1 183 3.1E-75 T 28-03-2018 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 Gene3D G3DSA:3.40.50.450 184 302 3.6E-18 T 28-03-2018 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 ProSitePatterns PS00433 Phosphofructokinase signature. 245 263 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 214 226 1.2E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 140 158 1.2E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.2E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 178 195 1.2E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.2E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.2E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 160 176 1.2E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 122 139 1.2E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 241 263 1.2E-86 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 301 6.2E-130 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 Pfam PF00365 Phosphofructokinase 3 277 1.3E-109 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 PIRSF PIRSF000532 1 322 1.4E-119 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CWR44_RS11355 376aeb684eeab9226d283ca6b7b107c1 322 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 321 46.832 T 28-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CWR44_RS01195 72b0e2d7351cd05d8d5ca8c29ab4daf3 108 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 2 107 21.813 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CWR44_RS01195 72b0e2d7351cd05d8d5ca8c29ab4daf3 108 SUPERFAMILY SSF103481 7 107 3.27E-11 T 28-03-2018 CWR44_RS01195 72b0e2d7351cd05d8d5ca8c29ab4daf3 108 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 1 108 1.3E-42 T 28-03-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CWR44_RS12810 e8bb04c4d887311af7584f1c87e4490d 159 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 2 158 37.862 T 28-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CWR44_RS12810 e8bb04c4d887311af7584f1c87e4490d 159 Gene3D G3DSA:3.30.565.10 3 157 2.9E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS12810 e8bb04c4d887311af7584f1c87e4490d 159 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 4 154 1.1E-75 T 28-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CWR44_RS12810 e8bb04c4d887311af7584f1c87e4490d 159 SUPERFAMILY SSF55874 35 135 1.31E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS12810 e8bb04c4d887311af7584f1c87e4490d 159 Pfam PF13581 Histidine kinase-like ATPase domain 12 142 6.5E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 Pfam PF00344 SecY translocase 69 412 4.5E-109 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 ProSitePatterns PS00756 Protein secY signature 2. 166 183 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 SUPERFAMILY SSF103491 1 418 6.67E-123 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 ProSitePatterns PS00755 Protein secY signature 1. 69 88 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 424 4.8E-146 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 173 196 4.8E-99 T 28-03-2018 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 268 287 4.8E-99 T 28-03-2018 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 4.8E-99 T 28-03-2018 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 4.8E-99 T 28-03-2018 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 68 88 4.8E-99 T 28-03-2018 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 363 381 4.8E-99 T 28-03-2018 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 308 330 4.8E-99 T 28-03-2018 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 110 133 4.8E-99 T 28-03-2018 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 147 172 4.8E-99 T 28-03-2018 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 PIRSF PIRSF004557 1 428 1.6E-129 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 428 28.532 T 28-03-2018 IPR026593 Protein translocase subunit SecY CWR44_RS00695 6b7382f1bc7fbe8648d6c6b47d6378cb 430 Gene3D G3DSA:1.10.3370.10 1 430 1.3E-148 T 28-03-2018 CWR44_RS03995 12f2570fd13718e9348ae5ec0c9f3328 205 Pfam PF03596 Cadmium resistance transporter 12 203 1.4E-88 T 28-03-2018 IPR004676 Cadmium resistance transporter CWR44_RS03995 12f2570fd13718e9348ae5ec0c9f3328 205 TIGRFAM TIGR00779 cad: cadmium resistance transporter family protein 12 205 1.2E-88 T 28-03-2018 IPR004676 Cadmium resistance transporter CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 SUPERFAMILY SSF52425 5 181 7.72E-18 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 Gene3D G3DSA:3.40.50.620 2 159 9.8E-14 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 Pfam PF00875 DNA photolyase 11 158 7.9E-9 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 Gene3D G3DSA:1.25.40.80 160 273 3.5E-18 T 28-03-2018 CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 Pfam PF03441 FAD binding domain of DNA photolyase 257 455 8.1E-79 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 SUPERFAMILY SSF48173 187 456 2.49E-96 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 PRINTS PR00147 DNA photolyase signature 138 154 2.9E-24 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 PRINTS PR00147 DNA photolyase signature 306 322 2.9E-24 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 PRINTS PR00147 DNA photolyase signature 326 344 2.9E-24 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 PRINTS PR00147 DNA photolyase signature 365 379 2.9E-24 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CWR44_RS06485 3687b05c61e51f91aaad43c8ad9ad67b 457 Gene3D G3DSA:1.10.579.10 275 457 1.7E-68 T 28-03-2018 CWR44_RS02315 ea5d8a4924983e54c9aea10e5d6a236b 352 Pfam PF13303 Phosphotransferase system, EIIC 16 349 9.8E-92 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS01050 bfee33e50ed1afb805f13539d679442f 157 Pfam PF07849 Protein of unknown function (DUF1641) 117 154 2.8E-10 T 28-03-2018 IPR012440 Protein of unknown function DUF1641 CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 Gene3D G3DSA:3.40.50.720 10 258 9.6E-77 T 28-03-2018 CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 9.0E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 9.0E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 9.0E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 256 8.5E-69 T 28-03-2018 CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.2E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWR44_RS03540 b033c2df9b7e4620e8017f7eb88bc552 258 SUPERFAMILY SSF51735 9 257 1.81E-84 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 SMART SM00028 167 197 300.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 SMART SM00028 234 267 35.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 SMART SM00028 96 129 260.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 SMART SM00028 200 233 28.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 Gene3D G3DSA:1.25.40.10 183 258 2.5E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 Gene3D G3DSA:1.25.40.10 316 414 6.6E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 SUPERFAMILY SSF81901 203 403 8.63E-14 T 28-03-2018 CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 Pfam PF13174 Tetratricopeptide repeat 33 64 0.096 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 SUPERFAMILY SSF48452 76 272 2.23E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 Gene3D G3DSA:1.25.40.10 259 315 7.7E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS10285 854ca68b1c1632dced62d34572186d15 414 Gene3D G3DSA:1.25.40.10 16 182 3.8E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS02725 84d2c05de6e61e970e26eb499be634fa 207 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 1.9E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS02725 84d2c05de6e61e970e26eb499be634fa 207 Gene3D G3DSA:2.160.10.10 3 206 1.3E-40 T 28-03-2018 CWR44_RS02725 84d2c05de6e61e970e26eb499be634fa 207 SUPERFAMILY SSF51161 33 192 2.75E-39 T 28-03-2018 IPR011004 Trimeric LpxA-like CWR44_RS02725 84d2c05de6e61e970e26eb499be634fa 207 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 125 153 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWR44_RS11260 8dcc9b154ad5df7e95867a25e3f91a88 118 Gene3D G3DSA:1.10.1900.20 55 116 2.1E-30 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11260 8dcc9b154ad5df7e95867a25e3f91a88 118 Pfam PF00453 Ribosomal protein L20 3 109 6.8E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11260 8dcc9b154ad5df7e95867a25e3f91a88 118 SUPERFAMILY SSF74731 2 117 1.16E-49 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11260 8dcc9b154ad5df7e95867a25e3f91a88 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.579 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11260 8dcc9b154ad5df7e95867a25e3f91a88 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.1E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11260 8dcc9b154ad5df7e95867a25e3f91a88 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.1E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11260 8dcc9b154ad5df7e95867a25e3f91a88 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.1E-41 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11260 8dcc9b154ad5df7e95867a25e3f91a88 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.2E-51 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11260 8dcc9b154ad5df7e95867a25e3f91a88 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 8.0E-16 T 28-03-2018 CWR44_RS11260 8dcc9b154ad5df7e95867a25e3f91a88 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS02430 afc6c6a5a9c46aec5c870ae398bb4568 271 Pfam PF03180 NLPA lipoprotein 30 267 4.7E-81 T 28-03-2018 IPR004872 Lipoprotein NlpA family CWR44_RS02430 afc6c6a5a9c46aec5c870ae398bb4568 271 Gene3D G3DSA:3.40.190.10 124 268 3.1E-39 T 28-03-2018 CWR44_RS02430 afc6c6a5a9c46aec5c870ae398bb4568 271 Gene3D G3DSA:3.40.190.10 29 123 1.8E-23 T 28-03-2018 CWR44_RS02430 afc6c6a5a9c46aec5c870ae398bb4568 271 SUPERFAMILY SSF53850 29 268 5.69E-70 T 28-03-2018 CWR44_RS02430 afc6c6a5a9c46aec5c870ae398bb4568 271 PIRSF PIRSF002854 1 269 9.4E-88 T 28-03-2018 IPR004872 Lipoprotein NlpA family CWR44_RS09430 aecd6fa4d012ec8de6b351a0471d4237 133 SUPERFAMILY SSF47413 13 76 5.63E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS09430 aecd6fa4d012ec8de6b351a0471d4237 133 Pfam PF01381 Helix-turn-helix 20 71 3.6E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS09430 aecd6fa4d012ec8de6b351a0471d4237 133 SMART SM00530 17 73 8.9E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS09430 aecd6fa4d012ec8de6b351a0471d4237 133 Gene3D G3DSA:1.10.260.40 4 133 1.2E-16 T 28-03-2018 CWR44_RS11005 6add5390aca442dbf821f58ddf08ce89 370 Gene3D G3DSA:3.40.50.620 2 212 4.5E-69 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS11005 6add5390aca442dbf821f58ddf08ce89 370 Pfam PF03054 tRNA methyl transferase 7 356 4.2E-146 T 28-03-2018 CWR44_RS11005 6add5390aca442dbf821f58ddf08ce89 370 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 6 357 40.157 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CWR44_RS11005 6add5390aca442dbf821f58ddf08ce89 370 Gene3D G3DSA:2.40.30.10 278 369 8.3E-27 T 28-03-2018 CWR44_RS11005 6add5390aca442dbf821f58ddf08ce89 370 SUPERFAMILY SSF52402 7 243 2.14E-58 T 28-03-2018 CWR44_RS11005 6add5390aca442dbf821f58ddf08ce89 370 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 7 356 3.5E-137 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CWR44_RS11005 6add5390aca442dbf821f58ddf08ce89 370 Gene3D G3DSA:2.30.30.280 213 276 8.7E-25 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CWR44_RS09130 a70b0ca7f5f7dd6dc4ec147aed7d5653 240 Gene3D G3DSA:3.90.226.10 1 201 2.0E-30 T 28-03-2018 CWR44_RS09130 a70b0ca7f5f7dd6dc4ec147aed7d5653 240 Pfam PF00574 Clp protease 8 184 7.5E-31 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CWR44_RS09130 a70b0ca7f5f7dd6dc4ec147aed7d5653 240 SUPERFAMILY SSF52096 5 188 5.94E-47 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWR44_RS09130 a70b0ca7f5f7dd6dc4ec147aed7d5653 240 PRINTS PR00127 Clp protease catalytic subunit P signature 161 180 4.1E-9 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR44_RS09130 a70b0ca7f5f7dd6dc4ec147aed7d5653 240 PRINTS PR00127 Clp protease catalytic subunit P signature 84 101 4.1E-9 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR44_RS09130 a70b0ca7f5f7dd6dc4ec147aed7d5653 240 PRINTS PR00127 Clp protease catalytic subunit P signature 53 73 4.1E-9 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR44_RS10910 cb4f88196f68294c4d7310f0a3b91def 175 Gene3D G3DSA:3.40.50.1000 18 150 9.7E-22 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS10910 cb4f88196f68294c4d7310f0a3b91def 175 Pfam PF08282 haloacid dehalogenase-like hydrolase 33 88 1.1E-4 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS10910 cb4f88196f68294c4d7310f0a3b91def 175 Pfam PF13242 HAD-hyrolase-like 94 139 1.0E-8 T 28-03-2018 CWR44_RS10910 cb4f88196f68294c4d7310f0a3b91def 175 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 31 141 3.5E-23 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CWR44_RS10910 cb4f88196f68294c4d7310f0a3b91def 175 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 6 169 1.6E-50 T 28-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like CWR44_RS10910 cb4f88196f68294c4d7310f0a3b91def 175 SUPERFAMILY SSF56784 4 153 1.42E-24 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS07755 82f4d59c7b3d6ac6e2e73f4e0c1658f1 140 Pfam PF13673 Acetyltransferase (GNAT) domain 20 139 7.4E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS07755 82f4d59c7b3d6ac6e2e73f4e0c1658f1 140 SUPERFAMILY SSF55729 5 140 7.72E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS07755 82f4d59c7b3d6ac6e2e73f4e0c1658f1 140 Gene3D G3DSA:3.40.630.30 3 140 3.4E-35 T 28-03-2018 CWR44_RS10015 ceb36a5cdd47c0f3e27f6c3aae840c68 89 Pfam PF00708 Acylphosphatase 5 87 8.6E-22 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CWR44_RS10015 ceb36a5cdd47c0f3e27f6c3aae840c68 89 SUPERFAMILY SSF54975 1 87 8.29E-25 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CWR44_RS10015 ceb36a5cdd47c0f3e27f6c3aae840c68 89 Gene3D G3DSA:3.30.70.100 1 89 3.4E-25 T 28-03-2018 CWR44_RS10015 ceb36a5cdd47c0f3e27f6c3aae840c68 89 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CWR44_RS05620 c70c5042900e72cbe54faa4f5ecde521 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05620 c70c5042900e72cbe54faa4f5ecde521 166 Pfam PF00466 Ribosomal protein L10 6 101 4.0E-29 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CWR44_RS05620 c70c5042900e72cbe54faa4f5ecde521 166 SUPERFAMILY SSF160369 5 160 5.49E-53 T 28-03-2018 CWR44_RS05620 c70c5042900e72cbe54faa4f5ecde521 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 28.473 T 28-03-2018 IPR022973 Ribosomal protein L10 CWR44_RS05620 c70c5042900e72cbe54faa4f5ecde521 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 12 144 0.005 T 28-03-2018 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 459 33.584 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 PRINTS PR00449 Transforming protein P21 ras signature 326 339 8.5E-5 T 28-03-2018 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 PRINTS PR00449 Transforming protein P21 ras signature 222 243 8.5E-5 T 28-03-2018 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 PRINTS PR00449 Transforming protein P21 ras signature 262 284 8.5E-5 T 28-03-2018 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 Gene3D G3DSA:1.20.120.430 287 459 2.1E-33 T 28-03-2018 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 Gene3D G3DSA:1.20.120.430 126 286 6.0E-26 T 28-03-2018 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 Pfam PF12631 MnmE helical domain 127 456 9.0E-57 T 28-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 124 1.8E-37 T 28-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 Pfam PF01926 50S ribosome-binding GTPase 225 336 1.1E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 SUPERFAMILY SSF52540 78 167 3.4E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 SUPERFAMILY SSF52540 202 372 3.4E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 Gene3D G3DSA:3.30.1360.120 1 125 1.1E-41 T 28-03-2018 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 SUPERFAMILY SSF116878 125 225 2.62E-48 T 28-03-2018 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 SUPERFAMILY SSF116878 384 459 2.62E-48 T 28-03-2018 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 459 7.1E-129 T 28-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CWR44_RS04460 caeae7ee573abac3f10c3bb8fa5a6b9e 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 225 371 2.4E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CWR44_RS08685 ee286c7c280d316bce8bb7fc63119a5c 257 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 257 130.659 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CWR44_RS08685 ee286c7c280d316bce8bb7fc63119a5c 257 Pfam PF08222 CodY helix-turn-helix domain 198 256 6.1E-34 T 28-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CWR44_RS08685 ee286c7c280d316bce8bb7fc63119a5c 257 Pfam PF06018 CodY GAF-like domain 2 178 4.0E-69 T 28-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CWR44_RS08685 ee286c7c280d316bce8bb7fc63119a5c 257 SUPERFAMILY SSF46785 167 255 1.11E-40 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS08685 ee286c7c280d316bce8bb7fc63119a5c 257 Gene3D G3DSA:1.10.10.10 160 257 2.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS08685 ee286c7c280d316bce8bb7fc63119a5c 257 PIRSF PIRSF011572 1 257 2.4E-115 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CWR44_RS08685 ee286c7c280d316bce8bb7fc63119a5c 257 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 1.2E-106 T 28-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CWR44_RS08685 ee286c7c280d316bce8bb7fc63119a5c 257 Gene3D G3DSA:3.30.450.40 1 159 6.9E-25 T 28-03-2018 IPR029016 GAF domain-like CWR44_RS05195 0ded1cddba47e31f7357cbcf32f48823 175 SUPERFAMILY SSF55729 38 147 1.64E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS05195 0ded1cddba47e31f7357cbcf32f48823 175 Gene3D G3DSA:3.40.630.30 6 154 4.5E-14 T 28-03-2018 CWR44_RS05195 0ded1cddba47e31f7357cbcf32f48823 175 Pfam PF00583 Acetyltransferase (GNAT) family 53 123 3.3E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS10770 fabafff3d5aaf85087f2f83171f84453 111 Gene3D G3DSA:1.10.3830.10 1 108 3.6E-36 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CWR44_RS10770 fabafff3d5aaf85087f2f83171f84453 111 Pfam PF01219 Prokaryotic diacylglycerol kinase 6 106 3.9E-31 T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CWR44_RS10770 fabafff3d5aaf85087f2f83171f84453 111 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 59 70 - T 28-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 Gene3D G3DSA:3.20.20.10 9 219 9.5E-22 T 28-03-2018 IPR029066 PLP-binding barrel CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 Hamap MF_01201 Alanine racemase. 1 358 19.746 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 Pfam PF01168 Alanine racemase, N-terminal domain 13 224 8.1E-37 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 Gene3D G3DSA:2.40.37.10 220 353 2.7E-27 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 SUPERFAMILY SSF50621 231 350 7.32E-22 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 PRINTS PR00992 Alanine racemase signature 151 162 1.6E-18 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 PRINTS PR00992 Alanine racemase signature 270 285 1.6E-18 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 PRINTS PR00992 Alanine racemase signature 22 38 1.6E-18 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 PRINTS PR00992 Alanine racemase signature 290 307 1.6E-18 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 PRINTS PR00992 Alanine racemase signature 197 224 1.6E-18 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 PRINTS PR00992 Alanine racemase signature 58 76 1.6E-18 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 PRINTS PR00992 Alanine racemase signature 113 125 1.6E-18 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 Pfam PF00842 Alanine racemase, C-terminal domain 237 334 3.8E-18 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 SMART SM01005 236 358 5.5E-19 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS09990 ac4460d1fc8b4cd1b2ba98dec4993cbb 358 SUPERFAMILY SSF51419 20 227 1.18E-33 T 28-03-2018 IPR029066 PLP-binding barrel CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 Gene3D G3DSA:3.90.740.10 183 224 0.016 T 28-03-2018 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 Pfam PF09334 tRNA synthetases class I (M) 39 170 8.0E-19 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 803 23.19 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 SUPERFAMILY SSF52374 411 624 1.34E-146 T 28-03-2018 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 SUPERFAMILY SSF52374 3 224 1.34E-146 T 28-03-2018 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 SUPERFAMILY SSF47323 618 803 4.67E-40 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 Gene3D G3DSA:3.40.50.620 30 182 3.1E-54 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 Gene3D G3DSA:3.40.50.620 397 564 5.4E-54 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 Gene3D G3DSA:3.90.740.10 225 396 1.1E-59 T 28-03-2018 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 9.4E-58 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 9.4E-58 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 9.4E-58 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 9.4E-58 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 9.4E-58 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 9.4E-58 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 9.4E-58 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 396 4.7E-68 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 Pfam PF08264 Anticodon-binding domain of tRNA 656 767 1.4E-22 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 Gene3D G3DSA:1.10.730.10 565 803 2.8E-64 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 607 3.6E-20 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 3 804 0.0 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CWR44_RS11675 ddcad3ad8e390dab6617309fd764a9a3 804 SUPERFAMILY SSF50677 224 410 4.19E-55 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 PRINTS PR00069 Aldo-keto reductase signature 124 141 1.3E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 PRINTS PR00069 Aldo-keto reductase signature 36 60 1.3E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 PRINTS PR00069 Aldo-keto reductase signature 196 220 1.3E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 PRINTS PR00069 Aldo-keto reductase signature 158 187 1.3E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 PRINTS PR00069 Aldo-keto reductase signature 92 110 1.3E-52 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 40 57 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 Gene3D G3DSA:3.20.20.100 2 278 6.5E-99 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 SUPERFAMILY SSF51430 5 266 2.1E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 PIRSF PIRSF000097 1 274 6.2E-91 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 124 141 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 Pfam PF00248 Aldo/keto reductase family 23 261 5.3E-53 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CWR44_RS06545 ddaf837e40b7c8113755eb7d65221ca5 279 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CWR44_RS02340 2b142a0881d578774d953d8c75e96516 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 119 1.4E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWR44_RS02340 2b142a0881d578774d953d8c75e96516 125 Gene3D G3DSA:3.10.180.10 1 123 1.2E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS02340 2b142a0881d578774d953d8c75e96516 125 SUPERFAMILY SSF54593 1 123 1.18E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS06215 d840b382652218a9b0ae5a7beaacc1c2 264 SMART SM00382 49 235 3.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS06215 d840b382652218a9b0ae5a7beaacc1c2 264 Gene3D G3DSA:3.40.50.300 1 260 1.4E-49 T 28-03-2018 CWR44_RS06215 d840b382652218a9b0ae5a7beaacc1c2 264 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS06215 d840b382652218a9b0ae5a7beaacc1c2 264 SUPERFAMILY SSF52540 35 234 1.03E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06215 d840b382652218a9b0ae5a7beaacc1c2 264 Pfam PF00005 ABC transporter 40 171 4.6E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS00915 85e7e5aad2372a53e999324448bd42f2 168 Gene3D G3DSA:3.40.980.10 1 168 8.8E-37 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS00915 85e7e5aad2372a53e999324448bd42f2 168 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CWR44_RS00915 85e7e5aad2372a53e999324448bd42f2 168 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 13 157 9.4E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS00915 85e7e5aad2372a53e999324448bd42f2 168 Pfam PF00994 Probable molybdopterin binding domain 16 161 1.7E-33 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS00915 85e7e5aad2372a53e999324448bd42f2 168 PIRSF PIRSF006443 1 168 2.4E-64 T 28-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 CWR44_RS00915 85e7e5aad2372a53e999324448bd42f2 168 SMART SM00852 16 162 5.8E-28 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS00915 85e7e5aad2372a53e999324448bd42f2 168 SUPERFAMILY SSF53218 6 167 3.8E-42 T 28-03-2018 IPR001453 MoaB/Mog domain CWR44_RS03630 6ca211240c15d09f4e97bc8872668590 105 Gene3D G3DSA:1.20.58.80 3 101 1.0E-37 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR44_RS03630 6ca211240c15d09f4e97bc8872668590 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 9 100 4.4E-37 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR44_RS03630 6ca211240c15d09f4e97bc8872668590 105 PIRSF PIRSF000699 1 105 1.6E-38 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR44_RS03630 6ca211240c15d09f4e97bc8872668590 105 SUPERFAMILY SSF46973 2 101 8.76E-37 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR44_RS11895 c1098cffb526ec622745a5a9ac854f65 344 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 4 341 5.2E-119 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CWR44_RS11895 c1098cffb526ec622745a5a9ac854f65 344 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 5 342 45.763 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CWR44_RS11895 c1098cffb526ec622745a5a9ac854f65 344 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 8 339 1.2E-124 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CWR44_RS11895 c1098cffb526ec622745a5a9ac854f65 344 SUPERFAMILY SSF51726 3 342 7.19E-100 T 28-03-2018 CWR44_RS11895 c1098cffb526ec622745a5a9ac854f65 344 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 139 155 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CWR44_RS11895 c1098cffb526ec622745a5a9ac854f65 344 Gene3D G3DSA:3.20.20.210 3 344 8.3E-92 T 28-03-2018 CWR44_RS11895 c1098cffb526ec622745a5a9ac854f65 344 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 21 30 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CWR44_RS00995 16451c9e174cf04c8c1242cf8ba3800e 438 Pfam PF01610 Transposase 164 417 2.5E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS00995 16451c9e174cf04c8c1242cf8ba3800e 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 4.3E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS12460 16451c9e174cf04c8c1242cf8ba3800e 438 Pfam PF01610 Transposase 164 417 2.5E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS12460 16451c9e174cf04c8c1242cf8ba3800e 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 4.3E-13 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS11035 453c2563f9b69adc63d32ef15ff586dc 425 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 148 2.2E-16 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR44_RS11035 453c2563f9b69adc63d32ef15ff586dc 425 Gene3D G3DSA:3.40.50.300 4 142 4.9E-27 T 28-03-2018 CWR44_RS11035 453c2563f9b69adc63d32ef15ff586dc 425 Gene3D G3DSA:1.20.272.10 240 333 1.1E-34 T 28-03-2018 CWR44_RS11035 453c2563f9b69adc63d32ef15ff586dc 425 SUPERFAMILY SSF48019 241 423 1.36E-68 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CWR44_RS11035 453c2563f9b69adc63d32ef15ff586dc 425 SMART SM00382 42 154 5.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS11035 453c2563f9b69adc63d32ef15ff586dc 425 Gene3D G3DSA:1.10.3710.10 336 425 1.5E-27 T 28-03-2018 CWR44_RS11035 453c2563f9b69adc63d32ef15ff586dc 425 SUPERFAMILY SSF52540 6 223 3.18E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11035 453c2563f9b69adc63d32ef15ff586dc 425 Pfam PF16193 AAA C-terminal domain 178 255 3.7E-25 T 28-03-2018 IPR032423 AAA C-terminal domain CWR44_RS11035 453c2563f9b69adc63d32ef15ff586dc 425 Gene3D G3DSA:1.10.8.60 143 231 4.5E-20 T 28-03-2018 CWR44_RS11035 453c2563f9b69adc63d32ef15ff586dc 425 Pfam PF12002 MgsA AAA+ ATPase C terminal 256 421 7.9E-63 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CWR44_RS01975 e3620cda84623a7116e682ee84582426 654 Hamap MF_01854 Fructose-1,6-bisphosphatase class 3 [fbp]. 10 654 38.974 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CWR44_RS01975 e3620cda84623a7116e682ee84582426 654 SUPERFAMILY SSF56300 198 251 7.96E-10 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS01975 e3620cda84623a7116e682ee84582426 654 SUPERFAMILY SSF56300 42 67 7.96E-10 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS01975 e3620cda84623a7116e682ee84582426 654 SUPERFAMILY SSF56300 394 492 2.37E-8 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS01975 e3620cda84623a7116e682ee84582426 654 SUPERFAMILY SSF56300 199 244 2.37E-8 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS01975 e3620cda84623a7116e682ee84582426 654 SUPERFAMILY SSF56300 528 569 2.37E-8 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS01975 e3620cda84623a7116e682ee84582426 654 PIRSF PIRSF000906 6 654 0.0 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CWR44_RS01975 e3620cda84623a7116e682ee84582426 654 Gene3D G3DSA:3.60.21.10 25 584 9.9E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS01975 e3620cda84623a7116e682ee84582426 654 Pfam PF06874 Firmicute fructose-1,6-bisphosphatase 12 649 3.9E-281 T 28-03-2018 IPR009164 Fructose-1,6-bisphosphatase class 3 GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CWR44_RS06090 149606bd097ee5fc1375ad04463dfde5 264 Pfam PF00561 alpha/beta hydrolase fold 22 221 1.5E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS06090 149606bd097ee5fc1375ad04463dfde5 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 4.6E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS06090 149606bd097ee5fc1375ad04463dfde5 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 4.6E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS06090 149606bd097ee5fc1375ad04463dfde5 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 4.6E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS06090 149606bd097ee5fc1375ad04463dfde5 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 4.6E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS06090 149606bd097ee5fc1375ad04463dfde5 264 SUPERFAMILY SSF53474 6 259 1.44E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS06090 149606bd097ee5fc1375ad04463dfde5 264 Gene3D G3DSA:3.40.50.1820 19 261 8.4E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS11140 9bc16b01b2d800058fd7017f11bb2c6a 169 Pfam PF04093 rod shape-determining protein MreD 1 164 3.3E-26 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CWR44_RS11140 9bc16b01b2d800058fd7017f11bb2c6a 169 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 8 156 1.3E-23 T 28-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CWR44_RS06850 cebec307248e7ba4a3753ba72b5e8c58 282 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 255 8.1E-76 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWR44_RS06850 cebec307248e7ba4a3753ba72b5e8c58 282 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 260 17.737 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWR44_RS06850 cebec307248e7ba4a3753ba72b5e8c58 282 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 258 2.2E-70 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWR44_RS06850 cebec307248e7ba4a3753ba72b5e8c58 282 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 326 424 9.8E-8 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.4E-20 T 28-03-2018 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.4E-20 T 28-03-2018 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 1.4E-20 T 28-03-2018 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.4E-20 T 28-03-2018 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.4E-20 T 28-03-2018 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.3E-13 T 28-03-2018 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 1.3E-13 T 28-03-2018 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 231 245 1.3E-13 T 28-03-2018 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 1.3E-13 T 28-03-2018 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 SUPERFAMILY SSF51905 1 311 9.5E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 Gene3D G3DSA:3.40.50.720 143 314 2.1E-25 T 28-03-2018 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 3 434 3.7E-187 T 28-03-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 SUPERFAMILY SSF55424 319 438 1.37E-25 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 Gene3D G3DSA:3.50.50.60 7 114 1.2E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 295 1.4E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 Hamap MF_01608 Coenzyme A disulfide reductase [cdr]. 1 438 67.14 T 28-03-2018 IPR023536 Coenzyme A disulphide reductase, staphyolococci GO:0050451|GO:0055114 CWR44_RS07425 78e93a9e717bc5a5513d8585368855cf 440 Gene3D G3DSA:3.30.390.30 322 440 3.8E-17 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 Gene3D G3DSA:2.70.150.10 5 205 2.2E-24 T 28-03-2018 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 Gene3D G3DSA:3.40.50.1000 436 568 1.5E-33 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 7 673 38.892 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 304 310 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 Gene3D G3DSA:3.40.1110.10 313 435 9.6E-19 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 Pfam PF00122 E1-E2 ATPase 102 279 7.3E-37 T 28-03-2018 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 544 1.2E-22 T 28-03-2018 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 151 165 1.2E-22 T 28-03-2018 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 509 528 1.2E-22 T 28-03-2018 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 302 316 1.2E-22 T 28-03-2018 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 456 466 1.2E-22 T 28-03-2018 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 SUPERFAMILY SSF81665 29 99 1.31E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 SUPERFAMILY SSF81665 205 296 1.31E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 SUPERFAMILY SSF81665 566 624 1.31E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 SUPERFAMILY SSF81653 108 204 2.35E-22 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 SUPERFAMILY SSF56784 290 314 2.34E-37 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 SUPERFAMILY SSF56784 349 397 2.34E-37 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 SUPERFAMILY SSF56784 428 551 2.34E-37 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 4 669 0.0 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 Pfam PF00702 haloacid dehalogenase-like hydrolase 298 523 1.6E-34 T 28-03-2018 CWR44_RS04050 736ea5c6f344123e83f884fe7878e672 673 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 72 598 6.8E-82 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CWR44_RS07965 cf8540900763bdd665ac7a8e4ce90bc6 559 Gene3D G3DSA:3.60.15.10 2 448 4.5E-58 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS07965 cf8540900763bdd665ac7a8e4ce90bc6 559 Hamap MF_01491 Ribonuclease J [rnj]. 4 556 45.996 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CWR44_RS07965 cf8540900763bdd665ac7a8e4ce90bc6 559 Pfam PF00753 Metallo-beta-lactamase superfamily 18 167 1.1E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS07965 cf8540900763bdd665ac7a8e4ce90bc6 559 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 554 1.2E-207 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CWR44_RS07965 cf8540900763bdd665ac7a8e4ce90bc6 559 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 357 407 3.2E-9 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CWR44_RS07965 cf8540900763bdd665ac7a8e4ce90bc6 559 SUPERFAMILY SSF56281 11 423 2.92E-91 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS07965 cf8540900763bdd665ac7a8e4ce90bc6 559 SMART SM00849 21 215 6.6E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS07965 cf8540900763bdd665ac7a8e4ce90bc6 559 PIRSF PIRSF004803 1 556 1.4E-238 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CWR44_RS07965 cf8540900763bdd665ac7a8e4ce90bc6 559 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 28-03-2018 IPR001587 Ribonuclease J, conserved site CWR44_RS12395 b273b298339cb8a578fa5eddad2bb515 512 Pfam PF00474 Sodium:solute symporter family 47 447 6.7E-101 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR44_RS12395 b273b298339cb8a578fa5eddad2bb515 512 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 16 509 3.2E-225 T 28-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 CWR44_RS12395 b273b298339cb8a578fa5eddad2bb515 512 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 47 447 6.4E-91 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR44_RS12395 b273b298339cb8a578fa5eddad2bb515 512 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 429 449 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CWR44_RS12680 8a9d6dae41987dbd77c809d87cc428e7 74 Gene3D G3DSA:3.30.110.40 2 73 8.0E-18 T 28-03-2018 IPR001455 TusA-like domain CWR44_RS12680 8a9d6dae41987dbd77c809d87cc428e7 74 SUPERFAMILY SSF64307 2 73 2.62E-20 T 28-03-2018 IPR001455 TusA-like domain CWR44_RS12680 8a9d6dae41987dbd77c809d87cc428e7 74 Pfam PF01206 Sulfurtransferase TusA 5 73 5.1E-18 T 28-03-2018 IPR001455 TusA-like domain CWR44_RS03255 bea62fd3cd0f2833de39999cbeecc1c4 385 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 1 379 3.6E-113 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CWR44_RS03255 bea62fd3cd0f2833de39999cbeecc1c4 385 SUPERFAMILY SSF51338 354 382 1.3E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR44_RS03255 bea62fd3cd0f2833de39999cbeecc1c4 385 SUPERFAMILY SSF51338 4 55 1.3E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR44_RS03255 bea62fd3cd0f2833de39999cbeecc1c4 385 Gene3D G3DSA:2.30.40.10 336 381 6.9E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR44_RS03255 bea62fd3cd0f2833de39999cbeecc1c4 385 Pfam PF01979 Amidohydrolase family 53 380 1.4E-20 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CWR44_RS03255 bea62fd3cd0f2833de39999cbeecc1c4 385 SUPERFAMILY SSF51556 56 354 2.93E-94 T 28-03-2018 IPR032466 Metal-dependent hydrolase CWR44_RS03255 bea62fd3cd0f2833de39999cbeecc1c4 385 Gene3D G3DSA:2.30.40.10 2 70 3.1E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CWR44_RS03255 bea62fd3cd0f2833de39999cbeecc1c4 385 PIRSF PIRSF038994 3 384 3.9E-125 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CWR44_RS03255 bea62fd3cd0f2833de39999cbeecc1c4 385 Gene3D G3DSA:3.20.20.140 71 335 2.1E-97 T 28-03-2018 CWR44_RS02680 1cfbf562b2dfee54a29e42529d89cb15 315 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 84 232 3.8E-47 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR44_RS02680 1cfbf562b2dfee54a29e42529d89cb15 315 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 84 232 2.2E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR44_RS08145 e52bb0171f9efbeffed233eb7c11bde9 380 SUPERFAMILY SSF52374 2 105 2.81E-16 T 28-03-2018 CWR44_RS08145 e52bb0171f9efbeffed233eb7c11bde9 380 SUPERFAMILY SSF52374 145 227 2.81E-16 T 28-03-2018 CWR44_RS08145 e52bb0171f9efbeffed233eb7c11bde9 380 Pfam PF05636 HIGH Nucleotidyl Transferase 1 368 2.1E-116 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CWR44_RS08145 e52bb0171f9efbeffed233eb7c11bde9 380 Hamap MF_01539 UPF0348 protein . 2 376 36.415 T 28-03-2018 IPR008513 Uncharacterised protein family UPF0348 CWR44_RS08145 e52bb0171f9efbeffed233eb7c11bde9 380 Gene3D G3DSA:3.40.50.620 1 236 2.2E-44 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS07685 915850766259fbb26cd41c6287f6acc0 72 SMART SM00914 27 63 1.5E-12 T 28-03-2018 IPR014957 IDEAL domain CWR44_RS07685 915850766259fbb26cd41c6287f6acc0 72 Pfam PF08858 IDEAL domain 27 63 1.3E-14 T 28-03-2018 IPR014957 IDEAL domain CWR44_RS07720 043dc6a1527f1ec34836af4690f63438 272 Gene3D G3DSA:1.10.12.10 212 260 2.1E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal CWR44_RS07720 043dc6a1527f1ec34836af4690f63438 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CWR44_RS07720 043dc6a1527f1ec34836af4690f63438 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 267 6.5E-91 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CWR44_RS07720 043dc6a1527f1ec34836af4690f63438 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 55.441 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CWR44_RS07720 043dc6a1527f1ec34836af4690f63438 272 SUPERFAMILY SSF52096 5 268 2.99E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWR44_RS07720 043dc6a1527f1ec34836af4690f63438 272 Gene3D G3DSA:3.90.226.10 1 211 5.4E-62 T 28-03-2018 CWR44_RS07720 043dc6a1527f1ec34836af4690f63438 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 5.5E-129 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CWR44_RS06795 ffaa89c578360967230cc910fe3acc51 224 Gene3D G3DSA:3.40.50.2020 67 223 3.1E-17 T 28-03-2018 CWR44_RS06795 ffaa89c578360967230cc910fe3acc51 224 SUPERFAMILY SSF53271 79 223 9.37E-17 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 8 420 3.3E-103 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 Gene3D G3DSA:1.20.1250.20 254 483 4.5E-29 T 28-03-2018 CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 297 321 6.6E-13 T 28-03-2018 CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 6.6E-13 T 28-03-2018 CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 6.6E-13 T 28-03-2018 CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 6.6E-13 T 28-03-2018 CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 PRINTS PR01036 Tetracycline resistance protein TetB signature 392 411 6.6E-13 T 28-03-2018 CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 Pfam PF07690 Major Facilitator Superfamily 14 404 3.6E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 Gene3D G3DSA:1.20.1250.20 2 188 6.9E-35 T 28-03-2018 CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 SUPERFAMILY SSF103473 243 414 2.35E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 SUPERFAMILY SSF103473 3 190 2.35E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01590 c40de0e03bcf5e767df30f6a0f8f2c1c 483 SUPERFAMILY SSF103473 445 473 2.35E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS10145 b214f4bb0f309bb8e4713e1348b948e7 83 Gene3D G3DSA:3.30.1370.70 2 83 3.1E-21 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CWR44_RS10145 b214f4bb0f309bb8e4713e1348b948e7 83 SMART SM00932 4 83 2.0E-19 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CWR44_RS10145 b214f4bb0f309bb8e4713e1348b948e7 83 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 4 82 3.7E-22 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CWR44_RS10145 b214f4bb0f309bb8e4713e1348b948e7 83 SUPERFAMILY SSF110836 1 82 1.31E-27 T 28-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CWR44_RS10595 c8cd1b4516cfe695f25f6872ecdab0ff 492 SUPERFAMILY SSF53383 10 484 3.2E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS10595 c8cd1b4516cfe695f25f6872ecdab0ff 492 Gene3D G3DSA:3.90.1150.10 346 471 5.3E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS10595 c8cd1b4516cfe695f25f6872ecdab0ff 492 Gene3D G3DSA:3.40.640.10 84 345 5.9E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS10595 c8cd1b4516cfe695f25f6872ecdab0ff 492 Pfam PF00266 Aminotransferase class-V 162 281 8.5E-9 T 28-03-2018 IPR000192 Aminotransferase class V domain CWR44_RS10595 c8cd1b4516cfe695f25f6872ecdab0ff 492 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 8 486 58.619 T 28-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CWR44_RS09850 41b6506134b862fa8a0447588b29cb8a 345 SUPERFAMILY SSF101821 71 183 1.16E-31 T 28-03-2018 CWR44_RS09850 41b6506134b862fa8a0447588b29cb8a 345 PIRSF PIRSF001123 2 341 2.2E-41 T 28-03-2018 IPR008007 Peptidase M42 CWR44_RS09850 41b6506134b862fa8a0447588b29cb8a 345 Pfam PF05343 M42 glutamyl aminopeptidase 46 334 2.5E-85 T 28-03-2018 IPR008007 Peptidase M42 CWR44_RS09850 41b6506134b862fa8a0447588b29cb8a 345 Gene3D G3DSA:3.40.630.10 1 341 4.5E-44 T 28-03-2018 CWR44_RS09850 41b6506134b862fa8a0447588b29cb8a 345 SUPERFAMILY SSF53187 4 83 1.09E-53 T 28-03-2018 CWR44_RS09850 41b6506134b862fa8a0447588b29cb8a 345 SUPERFAMILY SSF53187 178 340 1.09E-53 T 28-03-2018 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 Gene3D G3DSA:3.40.50.300 10 37 0.0062 T 28-03-2018 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 923 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 Gene3D G3DSA:1.10.8.280 284 405 8.9E-39 T 28-03-2018 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 Gene3D G3DSA:3.40.50.300 38 138 6.9E-4 T 28-03-2018 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 SUPERFAMILY SSF52540 5 206 1.02E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 SUPERFAMILY SSF52540 430 569 1.02E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 SUPERFAMILY SSF52540 613 911 1.14E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 Pfam PF00005 ABC transporter 622 858 7.8E-9 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 Gene3D G3DSA:3.40.50.300 423 612 1.9E-27 T 28-03-2018 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 Gene3D G3DSA:3.30.190.20 139 247 2.3E-43 T 28-03-2018 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 Gene3D G3DSA:3.40.50.300 613 944 1.4E-56 T 28-03-2018 CWR44_RS06840 70ba42456474ef2d77a3790fae72aee4 944 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 23.124 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CWR44_RS01815 74476fbc6c5afe61e7dc3a03a4e7cc6d 525 Pfam PF01645 Conserved region in glutamate synthase 120 493 3.2E-103 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CWR44_RS01815 74476fbc6c5afe61e7dc3a03a4e7cc6d 525 SUPERFAMILY SSF51395 10 128 7.03E-113 T 28-03-2018 CWR44_RS01815 74476fbc6c5afe61e7dc3a03a4e7cc6d 525 SUPERFAMILY SSF51395 165 520 7.03E-113 T 28-03-2018 CWR44_RS01815 74476fbc6c5afe61e7dc3a03a4e7cc6d 525 PIRSF PIRSF006429 1 524 1.1E-159 T 28-03-2018 IPR024188 Glutamate synthase large subunit-like protein CWR44_RS01815 74476fbc6c5afe61e7dc3a03a4e7cc6d 525 Gene3D G3DSA:3.20.20.70 92 524 2.2E-92 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS01815 74476fbc6c5afe61e7dc3a03a4e7cc6d 525 PIRSF PIRSF500060 1 525 4.1E-218 T 28-03-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 415 432 2.5E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 367 383 2.5E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 224 238 2.5E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 253 263 2.5E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 317 329 2.5E-29 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 SUPERFAMILY SSF48013 3 126 2.88E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 6 433 4.6E-118 T 28-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 Gene3D G3DSA:1.10.940.10 1 143 3.3E-27 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 SUPERFAMILY SSF53335 135 432 8.29E-66 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 Pfam PF01029 NusB family 4 123 7.7E-30 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 430 1.5E-54 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 Gene3D G3DSA:3.40.50.150 233 435 5.3E-54 T 28-03-2018 CWR44_RS08490 bf57bbf97a9bc2404aeecaecc0639a5e 435 Gene3D G3DSA:3.30.70.1170 178 232 7.0E-11 T 28-03-2018 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 Gene3D G3DSA:3.30.479.20 57 156 3.1E-24 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 SUPERFAMILY SSF46934 1 55 2.7E-21 T 28-03-2018 IPR009060 UBA-like GO:0005515 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 292 2.5E-115 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 Pfam PF00889 Elongation factor TS 70 274 1.5E-76 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 Gene3D G3DSA:1.10.8.10 1 55 5.8E-26 T 28-03-2018 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 Gene3D G3DSA:3.30.479.20 157 290 9.9E-51 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 82.499 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 SUPERFAMILY SSF54713 151 292 1.83E-51 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS08695 b45bc228d3166ba9e46134e0f14b7ecd 292 SUPERFAMILY SSF54713 55 143 1.64E-22 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CWR44_RS06880 e320b9dc0a60f5cef692b8ccf4e2dbf9 314 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 35.159 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CWR44_RS06880 e320b9dc0a60f5cef692b8ccf4e2dbf9 314 SUPERFAMILY SSF55608 119 220 7.94E-19 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CWR44_RS06880 e320b9dc0a60f5cef692b8ccf4e2dbf9 314 Pfam PF14527 WhiA LAGLIDADG-like domain 124 216 1.3E-34 T 28-03-2018 CWR44_RS06880 e320b9dc0a60f5cef692b8ccf4e2dbf9 314 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 3.3E-133 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like CWR44_RS06880 e320b9dc0a60f5cef692b8ccf4e2dbf9 314 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 103 2.8E-33 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CWR44_RS06880 e320b9dc0a60f5cef692b8ccf4e2dbf9 314 Gene3D G3DSA:1.10.10.10 239 303 0.0019 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06880 e320b9dc0a60f5cef692b8ccf4e2dbf9 314 Pfam PF02650 WhiA C-terminal HTH domain 219 303 2.4E-36 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CWR44_RS06880 e320b9dc0a60f5cef692b8ccf4e2dbf9 314 Gene3D G3DSA:3.10.28.10 14 102 2.0E-9 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CWR44_RS06880 e320b9dc0a60f5cef692b8ccf4e2dbf9 314 Gene3D G3DSA:3.10.28.10 122 202 6.3E-15 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CWR44_RS06375 a07e41c65af52265414e2f8a3d8cb905 238 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 3.9E-71 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS06375 a07e41c65af52265414e2f8a3d8cb905 238 Gene3D G3DSA:3.30.70.980 172 238 1.6E-9 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS06375 a07e41c65af52265414e2f8a3d8cb905 238 SUPERFAMILY SSF75625 1 237 4.45E-82 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS06375 a07e41c65af52265414e2f8a3d8cb905 238 Gene3D G3DSA:3.30.70.980 80 171 5.2E-26 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS06375 a07e41c65af52265414e2f8a3d8cb905 238 Pfam PF01709 Transcriptional regulator 4 235 1.2E-81 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS06375 a07e41c65af52265414e2f8a3d8cb905 238 Gene3D G3DSA:1.10.10.200 2 76 1.3E-26 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CWR44_RS06375 a07e41c65af52265414e2f8a3d8cb905 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.076 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS06375 a07e41c65af52265414e2f8a3d8cb905 238 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 55.512 T 28-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN CWR44_RS10290 9742d3e25111db1a34e5b3a58509b708 432 ProSitePatterns PS00885 EPSP synthase signature 2. 342 360 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWR44_RS10290 9742d3e25111db1a34e5b3a58509b708 432 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 425 1.5E-111 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWR44_RS10290 9742d3e25111db1a34e5b3a58509b708 432 SUPERFAMILY SSF55205 11 425 9.42E-115 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CWR44_RS10290 9742d3e25111db1a34e5b3a58509b708 432 Gene3D G3DSA:3.65.10.10 217 429 2.1E-42 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR44_RS10290 9742d3e25111db1a34e5b3a58509b708 432 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 425 2.3E-126 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR44_RS10290 9742d3e25111db1a34e5b3a58509b708 432 PIRSF PIRSF000505 1 432 1.0E-105 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWR44_RS10290 9742d3e25111db1a34e5b3a58509b708 432 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 431 31.196 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWR44_RS10290 9742d3e25111db1a34e5b3a58509b708 432 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CWR44_RS10290 9742d3e25111db1a34e5b3a58509b708 432 Gene3D G3DSA:3.65.10.10 22 216 5.0E-41 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR44_RS07955 d5f05b1a096fb5cd68818d3d3784cb6d 128 Pfam PF04304 Protein of unknown function (DUF454) 2 113 3.4E-32 T 28-03-2018 IPR007401 Protein of unknown function DUF454 CWR44_RS07955 d5f05b1a096fb5cd68818d3d3784cb6d 128 PIRSF PIRSF016789 1 121 1.8E-34 T 28-03-2018 IPR007401 Protein of unknown function DUF454 CWR44_RS05040 2dd62a175eebfb8535082c60edba7f07 142 SUPERFAMILY SSF55729 14 128 2.19E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS05040 2dd62a175eebfb8535082c60edba7f07 142 Pfam PF13673 Acetyltransferase (GNAT) domain 29 139 8.8E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS05040 2dd62a175eebfb8535082c60edba7f07 142 Gene3D G3DSA:3.40.630.30 2 142 2.1E-17 T 28-03-2018 CWR44_RS02745 4cddc64a4b338c0350e2eec7bf255202 599 SUPERFAMILY SSF51735 281 546 7.35E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02745 4cddc64a4b338c0350e2eec7bf255202 599 Gene3D G3DSA:3.40.50.720 292 599 2.0E-67 T 28-03-2018 CWR44_RS02745 4cddc64a4b338c0350e2eec7bf255202 599 Pfam PF02719 Polysaccharide biosynthesis protein 284 567 8.5E-128 T 28-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CWR44_RS02745 4cddc64a4b338c0350e2eec7bf255202 599 Gene3D G3DSA:3.40.50.720 259 291 0.026 T 28-03-2018 CWR44_RS02745 4cddc64a4b338c0350e2eec7bf255202 599 Pfam PF13727 CoA-binding domain 69 234 9.4E-16 T 28-03-2018 CWR44_RS02745 4cddc64a4b338c0350e2eec7bf255202 599 Gene3D G3DSA:3.40.50.720 137 258 4.2E-27 T 28-03-2018 CWR44_RS02745 4cddc64a4b338c0350e2eec7bf255202 599 SUPERFAMILY SSF51735 139 271 6.69E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS12240 4e8a075b504fed6eefc7e4aeca44a12c 267 Gene3D G3DSA:1.10.10.10 44 107 8.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12240 4e8a075b504fed6eefc7e4aeca44a12c 267 Gene3D G3DSA:1.10.10.10 213 262 2.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12240 4e8a075b504fed6eefc7e4aeca44a12c 267 Gene3D G3DSA:1.10.10.10 158 205 8.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12240 4e8a075b504fed6eefc7e4aeca44a12c 267 Hamap MF_01114 Regulatory protein RecX [recX]. 42 208 15.647 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CWR44_RS12240 4e8a075b504fed6eefc7e4aeca44a12c 267 Pfam PF02631 RecX family 84 203 7.0E-24 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CWR44_RS12240 4e8a075b504fed6eefc7e4aeca44a12c 267 Gene3D G3DSA:1.10.10.10 109 150 4.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00735 0cbbcfdde57d2a25f01a344a7714ed58 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 28-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00735 0cbbcfdde57d2a25f01a344a7714ed58 179 SUPERFAMILY SSF55282 3 179 2.83E-79 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00735 0cbbcfdde57d2a25f01a344a7714ed58 179 Gene3D G3DSA:3.30.1440.10 1 179 5.8E-82 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00735 0cbbcfdde57d2a25f01a344a7714ed58 179 PIRSF PIRSF002161 1 179 1.7E-72 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00735 0cbbcfdde57d2a25f01a344a7714ed58 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 3.4E-42 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00735 0cbbcfdde57d2a25f01a344a7714ed58 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.126 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00735 0cbbcfdde57d2a25f01a344a7714ed58 179 Pfam PF00281 Ribosomal protein L5 24 80 7.0E-29 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS09985 c7f06c15f763bc83a3afec5db5891c36 383 PIRSF PIRSF005962 1 383 3.1E-116 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS09985 c7f06c15f763bc83a3afec5db5891c36 383 Gene3D G3DSA:3.40.630.10 234 383 7.5E-14 T 28-03-2018 CWR44_RS09985 c7f06c15f763bc83a3afec5db5891c36 383 Gene3D G3DSA:3.40.630.10 2 233 5.5E-39 T 28-03-2018 CWR44_RS09985 c7f06c15f763bc83a3afec5db5891c36 383 Pfam PF01546 Peptidase family M20/M25/M40 63 378 1.3E-34 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS09985 c7f06c15f763bc83a3afec5db5891c36 383 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 8 367 1.4E-89 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CWR44_RS09985 c7f06c15f763bc83a3afec5db5891c36 383 SUPERFAMILY SSF55031 178 290 2.99E-16 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS09985 c7f06c15f763bc83a3afec5db5891c36 383 SUPERFAMILY SSF53187 5 191 7.07E-71 T 28-03-2018 CWR44_RS09985 c7f06c15f763bc83a3afec5db5891c36 383 SUPERFAMILY SSF53187 292 380 7.07E-71 T 28-03-2018 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 85 108 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 259 273 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 TIGRFAM TIGR01810 betA: choline dehydrogenase 8 540 4.9E-281 T 28-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 Gene3D G3DSA:4.10.450.10 41 106 4.3E-22 T 28-03-2018 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 SUPERFAMILY SSF51905 476 538 1.42E-85 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 SUPERFAMILY SSF51905 4 293 1.42E-85 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 SUPERFAMILY SSF54373 295 477 4.12E-56 T 28-03-2018 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 Pfam PF05199 GMC oxidoreductase 392 530 2.9E-35 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 Gene3D G3DSA:3.30.560.10 107 492 2.9E-100 T 28-03-2018 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 PIRSF PIRSF000137 1 541 3.1E-137 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 Pfam PF00732 GMC oxidoreductase 7 300 2.9E-76 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CWR44_RS02555 95d12bc0acca9b92a6b8ab7ae0b6e326 568 Hamap MF_00750 Oxygen-dependent choline dehydrogenase [betA]. 5 557 60.917 T 28-03-2018 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494 CWR44_RS09315 87f794404d2e6bb97a0c058c5370cef1 178 SMART SM00318 46 178 1.2E-38 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CWR44_RS09315 87f794404d2e6bb97a0c058c5370cef1 178 SUPERFAMILY SSF50199 46 178 5.23E-37 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CWR44_RS09315 87f794404d2e6bb97a0c058c5370cef1 178 Pfam PF00565 Staphylococcal nuclease homologue 72 178 2.1E-33 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CWR44_RS09315 87f794404d2e6bb97a0c058c5370cef1 178 Gene3D G3DSA:2.40.50.90 39 178 1.0E-37 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CWR44_RS09315 87f794404d2e6bb97a0c058c5370cef1 178 ProSitePatterns PS01284 Thermonuclease family signature 2. 120 130 - T 28-03-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 CWR44_RS02975 794a32b3b48b47ab96c54f915a5a80f7 332 SMART SM00387 247 331 5.1E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS02975 794a32b3b48b47ab96c54f915a5a80f7 332 SUPERFAMILY SSF55874 209 327 2.62E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS02975 794a32b3b48b47ab96c54f915a5a80f7 332 Gene3D G3DSA:3.30.565.10 72 328 7.8E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS02975 794a32b3b48b47ab96c54f915a5a80f7 332 SUPERFAMILY SSF47384 125 192 7.06E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 Gene3D G3DSA:1.10.3120.10 213 399 1.2E-48 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 SUPERFAMILY SSF102735 1 130 1.09E-41 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 Hamap MF_00303 Trigger factor [tig]. 1 427 23.816 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 TIGRFAM TIGR00115 tig: trigger factor 14 420 4.1E-138 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 Gene3D G3DSA:3.30.70.1050 1 119 4.2E-40 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 SUPERFAMILY SSF109998 250 429 3.66E-40 T 28-03-2018 IPR027304 Trigger factor/SurA domain CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 420 6.2E-45 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 6.1E-47 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 232 6.6E-14 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 SUPERFAMILY SSF54534 89 243 1.32E-34 T 28-03-2018 CWR44_RS11245 2fc49e653d304bc294b16ce6ccf067bb 434 PIRSF PIRSF003095 1 434 1.1E-133 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CWR44_RS12230 bddffb4ab1f1cf7b2273da1d4719f640 503 SUPERFAMILY SSF52540 34 227 5.06E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS12230 bddffb4ab1f1cf7b2273da1d4719f640 503 Gene3D G3DSA:3.40.50.300 4 260 3.4E-23 T 28-03-2018 CWR44_RS12230 bddffb4ab1f1cf7b2273da1d4719f640 503 Pfam PF00005 ABC transporter 37 149 8.1E-9 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06410 c04cd14f2c796ebddaf615a7b3c81499 229 SUPERFAMILY SSF158560 3 94 8.89E-8 T 28-03-2018 CWR44_RS06410 c04cd14f2c796ebddaf615a7b3c81499 229 Gene3D G3DSA:1.10.1900.10 14 96 6.9E-12 T 28-03-2018 CWR44_RS06410 c04cd14f2c796ebddaf615a7b3c81499 229 Pfam PF06570 Protein of unknown function (DUF1129) 38 220 1.9E-11 T 28-03-2018 IPR009214 Protein of unknown function DUF1129 CWR44_RS09340 ba0c168432c4a19c96abb40818664d09 353 TIGRFAM TIGR00260 thrC: threonine synthase 9 325 3.1E-106 T 28-03-2018 IPR004450 Threonine synthase-like CWR44_RS09340 ba0c168432c4a19c96abb40818664d09 353 Gene3D G3DSA:3.40.50.1100 147 335 5.0E-50 T 28-03-2018 CWR44_RS09340 ba0c168432c4a19c96abb40818664d09 353 PIRSF PIRSF038945 1 350 3.8E-164 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CWR44_RS09340 ba0c168432c4a19c96abb40818664d09 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 318 4.8E-80 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR44_RS09340 ba0c168432c4a19c96abb40818664d09 353 Gene3D G3DSA:3.40.50.1100 39 146 1.2E-28 T 28-03-2018 CWR44_RS09340 ba0c168432c4a19c96abb40818664d09 353 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CWR44_RS09340 ba0c168432c4a19c96abb40818664d09 353 SUPERFAMILY SSF53686 8 351 1.83E-107 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR44_RS02730 74939873f98f1dd71333bea4ebf355dc 375 Gene3D G3DSA:3.40.50.2000 1 201 8.4E-71 T 28-03-2018 CWR44_RS02730 74939873f98f1dd71333bea4ebf355dc 375 SUPERFAMILY SSF53756 3 372 3.01E-106 T 28-03-2018 CWR44_RS02730 74939873f98f1dd71333bea4ebf355dc 375 Gene3D G3DSA:3.40.50.2000 202 344 3.5E-20 T 28-03-2018 CWR44_RS02730 74939873f98f1dd71333bea4ebf355dc 375 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 360 3.3E-89 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CWR44_RS02730 74939873f98f1dd71333bea4ebf355dc 375 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 363 1.5E-75 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 235 248 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 PRINTS PR00990 Ribokinase signature 6 27 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 PRINTS PR00990 Ribokinase signature 104 117 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 PRINTS PR00990 Ribokinase signature 33 52 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 PRINTS PR00990 Ribokinase signature 172 187 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 PRINTS PR00990 Ribokinase signature 206 217 2.9E-33 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 Hamap MF_01987 Ribokinase [rbsK]. 2 290 23.127 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 Pfam PF00294 pfkB family carbohydrate kinase 1 283 3.3E-62 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 SUPERFAMILY SSF53613 4 288 7.79E-72 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 288 6.1E-91 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CWR44_RS03700 b984efe4f4488c603d546a56a6eea539 293 Gene3D G3DSA:3.40.1190.20 1 292 5.2E-69 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS09295 e91d71ca175ba25581e959bada1553d6 365 SUPERFAMILY SSF55874 249 362 1.44E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS09295 e91d71ca175ba25581e959bada1553d6 365 Pfam PF07730 Histidine kinase 177 240 2.7E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CWR44_RS09295 e91d71ca175ba25581e959bada1553d6 365 Gene3D G3DSA:3.30.565.10 213 365 3.7E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS06770 27272841dc857cc7cf07ca92c20bb032 356 Gene3D G3DSA:3.30.70.270 180 352 9.8E-42 T 28-03-2018 CWR44_RS06770 27272841dc857cc7cf07ca92c20bb032 356 SUPERFAMILY SSF55073 193 350 6.75E-37 T 28-03-2018 IPR029787 Nucleotide cyclase CWR44_RS06770 27272841dc857cc7cf07ca92c20bb032 356 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 188 350 3.7E-41 T 28-03-2018 IPR000160 GGDEF domain CWR44_RS06770 27272841dc857cc7cf07ca92c20bb032 356 SMART SM00267 177 351 3.4E-37 T 28-03-2018 IPR000160 GGDEF domain CWR44_RS06770 27272841dc857cc7cf07ca92c20bb032 356 Pfam PF00990 Diguanylate cyclase, GGDEF domain 189 347 1.8E-35 T 28-03-2018 IPR000160 GGDEF domain CWR44_RS00610 c1e4d38e2cb59edbfebf29e88bfed494 171 PIRSF PIRSF005384 1 148 2.5E-52 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR44_RS00610 c1e4d38e2cb59edbfebf29e88bfed494 171 Gene3D G3DSA:3.40.1400.10 1 169 6.2E-56 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR44_RS00610 c1e4d38e2cb59edbfebf29e88bfed494 171 Hamap MF_01556 Galactose-6-phosphate isomerase subunit LacB [lacB]. 1 171 47.498 T 28-03-2018 IPR004784 Galactose-6-phosphate isomerase subunit LacB GO:0005990|GO:0016861|GO:0050044 KEGG: 00052+5.3.1.26 CWR44_RS00610 c1e4d38e2cb59edbfebf29e88bfed494 171 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 3.4E-38 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR44_RS00610 c1e4d38e2cb59edbfebf29e88bfed494 171 Pfam PF02502 Ribose/Galactose Isomerase 3 141 8.6E-43 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR44_RS00610 c1e4d38e2cb59edbfebf29e88bfed494 171 TIGRFAM TIGR01119 lacB: galactose-6-phosphate isomerase, LacB subunit 1 171 2.6E-108 T 28-03-2018 IPR004784 Galactose-6-phosphate isomerase subunit LacB GO:0005990|GO:0016861|GO:0050044 KEGG: 00052+5.3.1.26 CWR44_RS00610 c1e4d38e2cb59edbfebf29e88bfed494 171 SUPERFAMILY SSF89623 1 151 7.32E-50 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CWR44_RS08510 992a3270f0809a928ce41aabe33678b5 291 SUPERFAMILY SSF52540 65 289 4.55E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08510 992a3270f0809a928ce41aabe33678b5 291 Gene3D G3DSA:1.10.40.50 225 291 4.2E-21 T 28-03-2018 CWR44_RS08510 992a3270f0809a928ce41aabe33678b5 291 Gene3D G3DSA:2.40.50.140 1 61 3.8E-18 T 28-03-2018 CWR44_RS08510 992a3270f0809a928ce41aabe33678b5 291 Pfam PF03193 RsgA GTPase 59 223 8.2E-55 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CWR44_RS08510 992a3270f0809a928ce41aabe33678b5 291 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 288 36.362 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CWR44_RS08510 992a3270f0809a928ce41aabe33678b5 291 SUPERFAMILY SSF50249 3 62 7.2E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS08510 992a3270f0809a928ce41aabe33678b5 291 Pfam PF16745 RsgA N-terminal domain 3 56 1.1E-19 T 28-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CWR44_RS08510 992a3270f0809a928ce41aabe33678b5 291 Gene3D G3DSA:3.40.50.300 62 223 6.3E-20 T 28-03-2018 CWR44_RS08510 992a3270f0809a928ce41aabe33678b5 291 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 281 9.2E-77 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CWR44_RS08480 9901229913371a26d07574d1d7c1d337 162 Hamap MF_00163 Peptide deformylase [def]. 2 158 19.353 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS08480 9901229913371a26d07574d1d7c1d337 162 Gene3D G3DSA:3.90.45.10 1 161 2.8E-36 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS08480 9901229913371a26d07574d1d7c1d337 162 SUPERFAMILY SSF56420 3 160 2.49E-37 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS08480 9901229913371a26d07574d1d7c1d337 162 PRINTS PR01576 Peptide deformylase signature 119 148 1.0E-16 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS08480 9901229913371a26d07574d1d7c1d337 162 PRINTS PR01576 Peptide deformylase signature 33 62 1.0E-16 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS08480 9901229913371a26d07574d1d7c1d337 162 PRINTS PR01576 Peptide deformylase signature 100 118 1.0E-16 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS08480 9901229913371a26d07574d1d7c1d337 162 PRINTS PR01576 Peptide deformylase signature 88 99 1.0E-16 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS08480 9901229913371a26d07574d1d7c1d337 162 PIRSF PIRSF004749 1 162 1.0E-39 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS08480 9901229913371a26d07574d1d7c1d337 162 Pfam PF01327 Polypeptide deformylase 4 148 2.3E-34 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS04555 fd5e8d3d73e485d6e5df646387d3533b 539 Gene3D G3DSA:3.40.50.300 294 538 2.4E-45 T 28-03-2018 CWR44_RS04555 fd5e8d3d73e485d6e5df646387d3533b 539 Gene3D G3DSA:3.40.50.300 2 270 4.5E-49 T 28-03-2018 CWR44_RS04555 fd5e8d3d73e485d6e5df646387d3533b 539 Pfam PF12848 ABC transporter 228 320 3.1E-21 T 28-03-2018 IPR032781 ABC-transporter extension domain CWR44_RS04555 fd5e8d3d73e485d6e5df646387d3533b 539 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS04555 fd5e8d3d73e485d6e5df646387d3533b 539 SUPERFAMILY SSF52540 322 535 3.91E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04555 fd5e8d3d73e485d6e5df646387d3533b 539 SUPERFAMILY SSF52540 6 241 1.42E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04555 fd5e8d3d73e485d6e5df646387d3533b 539 Pfam PF00005 ABC transporter 20 189 1.4E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS04555 fd5e8d3d73e485d6e5df646387d3533b 539 Pfam PF00005 ABC transporter 348 477 3.2E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS04555 fd5e8d3d73e485d6e5df646387d3533b 539 SMART SM00382 356 521 6.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS04555 fd5e8d3d73e485d6e5df646387d3533b 539 SMART SM00382 28 234 1.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS09830 8a1be1c8cb7db1d00944d7054fbd510c 325 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 98 241 1.6E-48 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR44_RS09830 8a1be1c8cb7db1d00944d7054fbd510c 325 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 98 240 2.7E-34 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR44_RS11930 3af03ab4cedce2a3c536c885118fed29 324 Gene3D G3DSA:1.10.4030.10 46 132 3.2E-5 T 28-03-2018 CWR44_RS11930 3af03ab4cedce2a3c536c885118fed29 324 Gene3D G3DSA:3.10.50.40 135 245 7.0E-31 T 28-03-2018 CWR44_RS11930 3af03ab4cedce2a3c536c885118fed29 324 SUPERFAMILY SSF109998 68 157 2.08E-12 T 28-03-2018 IPR027304 Trigger factor/SurA domain CWR44_RS11930 3af03ab4cedce2a3c536c885118fed29 324 Pfam PF00639 PPIC-type PPIASE domain 146 244 9.2E-28 T 28-03-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CWR44_RS11930 3af03ab4cedce2a3c536c885118fed29 324 SUPERFAMILY SSF54534 139 243 3.27E-27 T 28-03-2018 CWR44_RS07270 71579cd29a7017fd92cb9b1f349806c8 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 8.4E-6 T 28-03-2018 CWR44_RS07270 71579cd29a7017fd92cb9b1f349806c8 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 8.4E-6 T 28-03-2018 CWR44_RS07270 71579cd29a7017fd92cb9b1f349806c8 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 8.4E-6 T 28-03-2018 CWR44_RS07270 71579cd29a7017fd92cb9b1f349806c8 402 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 8.4E-6 T 28-03-2018 CWR44_RS07270 71579cd29a7017fd92cb9b1f349806c8 402 Gene3D G3DSA:3.50.50.60 130 335 2.0E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07270 71579cd29a7017fd92cb9b1f349806c8 402 Gene3D G3DSA:3.50.50.60 4 129 9.5E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07270 71579cd29a7017fd92cb9b1f349806c8 402 SUPERFAMILY SSF51905 6 211 1.19E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07270 71579cd29a7017fd92cb9b1f349806c8 402 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 326 1.2E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07270 71579cd29a7017fd92cb9b1f349806c8 402 SUPERFAMILY SSF51905 154 339 3.09E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS00225 fcc01e633ad51a2393236b7901fb0982 199 SUPERFAMILY SSF52540 8 142 3.9E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00225 fcc01e633ad51a2393236b7901fb0982 199 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 28-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CWR44_RS00225 fcc01e633ad51a2393236b7901fb0982 199 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 36.743 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CWR44_RS00225 fcc01e633ad51a2393236b7901fb0982 199 Pfam PF00265 Thymidine kinase 8 187 1.2E-57 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CWR44_RS00225 fcc01e633ad51a2393236b7901fb0982 199 Gene3D G3DSA:3.40.50.300 7 141 2.7E-47 T 28-03-2018 CWR44_RS00225 fcc01e633ad51a2393236b7901fb0982 199 SUPERFAMILY SSF57716 142 191 4.63E-15 T 28-03-2018 CWR44_RS00225 fcc01e633ad51a2393236b7901fb0982 199 Gene3D G3DSA:3.30.60.20 142 199 1.6E-17 T 28-03-2018 CWR44_RS00225 fcc01e633ad51a2393236b7901fb0982 199 PIRSF PIRSF035805 5 199 4.2E-65 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CWR44_RS08380 fff2718687b7c6837e8ce1c9720c77b9 264 SUPERFAMILY SSF54593 158 258 1.11E-6 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS08380 fff2718687b7c6837e8ce1c9720c77b9 264 SUPERFAMILY SSF54593 10 166 1.13E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS08380 fff2718687b7c6837e8ce1c9720c77b9 264 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 119 5.9E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWR44_RS08380 fff2718687b7c6837e8ce1c9720c77b9 264 Gene3D G3DSA:3.10.180.10 64 225 1.2E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS08380 fff2718687b7c6837e8ce1c9720c77b9 264 Gene3D G3DSA:3.10.180.10 3 63 1.8E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS04580 0b036b98f3e23e96ccfc9236a5d912d6 391 Gene3D G3DSA:3.40.640.10 5 246 1.4E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS04580 0b036b98f3e23e96ccfc9236a5d912d6 391 PIRSF PIRSF001434 3 375 6.6E-124 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS04580 0b036b98f3e23e96ccfc9236a5d912d6 391 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 188 202 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS04580 0b036b98f3e23e96ccfc9236a5d912d6 391 Gene3D G3DSA:3.90.1150.10 248 386 4.2E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS04580 0b036b98f3e23e96ccfc9236a5d912d6 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 16 373 1.6E-122 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS04580 0b036b98f3e23e96ccfc9236a5d912d6 391 SUPERFAMILY SSF53383 25 374 7.8E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS07245 3485ba2635fc07a32d55fdeeb14a7fae 80 SUPERFAMILY SSF117916 3 79 6.76E-26 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CWR44_RS07245 3485ba2635fc07a32d55fdeeb14a7fae 80 Pfam PF01106 NifU-like domain 12 77 8.5E-27 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CWR44_RS07245 3485ba2635fc07a32d55fdeeb14a7fae 80 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 17 79 5.0E-30 T 28-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CWR44_RS07245 3485ba2635fc07a32d55fdeeb14a7fae 80 Gene3D G3DSA:3.30.300.130 3 80 1.3E-28 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 SMART SM00257 89 132 1.3E-15 T 28-03-2018 IPR018392 LysM domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 SMART SM00257 29 72 6.4E-17 T 28-03-2018 IPR018392 LysM domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 SMART SM00257 153 196 1.8E-15 T 28-03-2018 IPR018392 LysM domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 SUPERFAMILY SSF54001 204 328 1.86E-16 T 28-03-2018 CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 SUPERFAMILY SSF54106 28 72 1.57E-11 T 28-03-2018 IPR018392 LysM domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 SUPERFAMILY SSF54106 153 195 5.49E-12 T 28-03-2018 IPR018392 LysM domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 Pfam PF01476 LysM domain 30 71 4.2E-14 T 28-03-2018 IPR018392 LysM domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 Pfam PF01476 LysM domain 90 131 2.7E-15 T 28-03-2018 IPR018392 LysM domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 Pfam PF01476 LysM domain 154 195 4.0E-15 T 28-03-2018 IPR018392 LysM domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 Pfam PF05257 CHAP domain 223 304 7.1E-14 T 28-03-2018 IPR007921 CHAP domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 Gene3D G3DSA:3.10.350.10 146 214 7.3E-17 T 28-03-2018 CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 SUPERFAMILY SSF54106 89 131 1.57E-11 T 28-03-2018 IPR018392 LysM domain CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 Gene3D G3DSA:3.10.350.10 84 145 5.1E-16 T 28-03-2018 CWR44_RS05125 19d277694e16549a7343d42ec7123db3 329 Gene3D G3DSA:3.10.350.10 23 83 1.7E-15 T 28-03-2018 CWR44_RS08390 3353bdda8b3b148e2ef405cb9940103e 158 TIGRFAM TIGR00077 lspA: signal peptidase II 10 156 9.0E-39 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR44_RS08390 3353bdda8b3b148e2ef405cb9940103e 158 ProSitePatterns PS00855 Signal peptidases II signature. 99 111 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR44_RS08390 3353bdda8b3b148e2ef405cb9940103e 158 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 52 60 2.2E-17 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR44_RS08390 3353bdda8b3b148e2ef405cb9940103e 158 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 96 111 2.2E-17 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR44_RS08390 3353bdda8b3b148e2ef405cb9940103e 158 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 132 148 2.2E-17 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR44_RS08390 3353bdda8b3b148e2ef405cb9940103e 158 Pfam PF01252 Signal peptidase (SPase) II 14 151 7.7E-35 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR44_RS08390 3353bdda8b3b148e2ef405cb9940103e 158 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 5 157 17.421 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CWR44_RS00360 b016553683cb7dca788b60cb1c949961 109 SUPERFAMILY SSF46785 8 100 5.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00360 b016553683cb7dca788b60cb1c949961 109 Pfam PF01022 Bacterial regulatory protein, arsR family 26 72 2.3E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS00360 b016553683cb7dca788b60cb1c949961 109 Gene3D G3DSA:1.10.10.10 3 106 5.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00360 b016553683cb7dca788b60cb1c949961 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 1.4E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS00360 b016553683cb7dca788b60cb1c949961 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 1.4E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS00360 b016553683cb7dca788b60cb1c949961 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 1.4E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS00360 b016553683cb7dca788b60cb1c949961 109 SMART SM00418 19 97 1.0E-27 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS12740 5b9bded166a0ac1ceeb4425da94aa001 510 SUPERFAMILY SSF110921 403 495 9.81E-17 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR44_RS12740 5b9bded166a0ac1ceeb4425da94aa001 510 SMART SM00917 369 500 2.3E-30 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR44_RS12740 5b9bded166a0ac1ceeb4425da94aa001 510 Pfam PF08502 LeuA allosteric (dimerisation) domain 370 498 2.1E-33 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR44_RS12740 5b9bded166a0ac1ceeb4425da94aa001 510 Gene3D G3DSA:3.20.20.70 1 328 1.1E-107 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS12740 5b9bded166a0ac1ceeb4425da94aa001 510 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 5 495 7.3E-197 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR44_RS12740 5b9bded166a0ac1ceeb4425da94aa001 510 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 509 39.666 T 28-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CWR44_RS12740 5b9bded166a0ac1ceeb4425da94aa001 510 Pfam PF00682 HMGL-like 5 273 2.2E-92 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CWR44_RS12740 5b9bded166a0ac1ceeb4425da94aa001 510 SUPERFAMILY SSF51569 1 291 7.33E-95 T 28-03-2018 CWR44_RS08520 558d88590058300f1736d3a23077cc76 213 SMART SM00983 140 205 2.1E-22 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR44_RS08520 558d88590058300f1736d3a23077cc76 213 SUPERFAMILY SSF63862 131 210 1.31E-16 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR44_RS08520 558d88590058300f1736d3a23077cc76 213 SUPERFAMILY SSF63999 2 128 1.28E-29 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR44_RS08520 558d88590058300f1736d3a23077cc76 213 Gene3D G3DSA:3.40.50.10240 2 115 9.8E-20 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR44_RS08520 558d88590058300f1736d3a23077cc76 213 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 206 6.1E-54 T 28-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR44_RS08520 558d88590058300f1736d3a23077cc76 213 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 27 123 2.0E-16 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR44_RS08520 558d88590058300f1736d3a23077cc76 213 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 142 203 1.1E-14 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR44_RS08520 558d88590058300f1736d3a23077cc76 213 Gene3D G3DSA:2.60.120.320 116 213 1.8E-20 T 28-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CWR44_RS00875 dae82bb46bf286dd768eef0c8cba9022 117 Gene3D G3DSA:1.10.10.10 1 115 2.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00875 dae82bb46bf286dd768eef0c8cba9022 117 SUPERFAMILY SSF46785 6 113 1.82E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00875 dae82bb46bf286dd768eef0c8cba9022 117 TIGRFAM TIGR01889 Staph_reg_Sar: staphylococcal accessory regulator family 7 113 3.1E-27 T 28-03-2018 IPR010166 Transcriptional regulator SarA/Rot GO:0006355 CWR44_RS02230 cc34121554e643195ec1e8a41e39d8e8 182 Gene3D G3DSA:1.10.10.60 49 133 9.6E-5 T 28-03-2018 CWR44_RS02230 cc34121554e643195ec1e8a41e39d8e8 182 Gene3D G3DSA:1.10.10.60 3 48 9.2E-9 T 28-03-2018 CWR44_RS02230 cc34121554e643195ec1e8a41e39d8e8 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 60 4.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS02230 cc34121554e643195ec1e8a41e39d8e8 182 SUPERFAMILY SSF46689 6 70 1.51E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS02705 0980fd23e09d6cb27c562baeb75cd220 402 SUPERFAMILY SSF53756 5 399 8.37E-24 T 28-03-2018 CWR44_RS02705 0980fd23e09d6cb27c562baeb75cd220 402 Gene3D G3DSA:3.40.50.2000 127 386 6.2E-16 T 28-03-2018 CWR44_RS02705 0980fd23e09d6cb27c562baeb75cd220 402 Pfam PF00534 Glycosyl transferases group 1 217 312 1.7E-6 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWR44_RS02240 e8610a93643825446ec71851862bc867 514 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 514 69.846 T 28-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CWR44_RS02240 e8610a93643825446ec71851862bc867 514 Gene3D G3DSA:3.40.309.10 302 489 4.0E-63 T 28-03-2018 CWR44_RS02240 e8610a93643825446ec71851862bc867 514 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS02240 e8610a93643825446ec71851862bc867 514 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 514 1.2E-220 T 28-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CWR44_RS02240 e8610a93643825446ec71851862bc867 514 Gene3D G3DSA:3.40.605.10 22 301 9.1E-79 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS02240 e8610a93643825446ec71851862bc867 514 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS02240 e8610a93643825446ec71851862bc867 514 Pfam PF00171 Aldehyde dehydrogenase family 49 510 2.0E-156 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS02240 e8610a93643825446ec71851862bc867 514 SUPERFAMILY SSF53720 4 510 1.05E-151 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR44_RS10865 194f294f38a98fb1e2213497ce193dc1 152 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 1.1E-30 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CWR44_RS10865 194f294f38a98fb1e2213497ce193dc1 152 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 150 5.3E-88 T 28-03-2018 IPR013404 Competence operon E, ComEB CWR44_RS10865 194f294f38a98fb1e2213497ce193dc1 152 PIRSF PIRSF006019 1 149 9.7E-62 T 28-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CWR44_RS10865 194f294f38a98fb1e2213497ce193dc1 152 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 105 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWR44_RS10865 194f294f38a98fb1e2213497ce193dc1 152 Gene3D G3DSA:3.40.140.10 3 149 8.2E-43 T 28-03-2018 CWR44_RS10865 194f294f38a98fb1e2213497ce193dc1 152 SUPERFAMILY SSF53927 7 140 1.95E-43 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR44_RS10960 f018c6cd18adec0588b4465b96c28a6e 422 ProSitePatterns PS01276 Peptidase family U32 signature. 175 193 - T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWR44_RS10960 f018c6cd18adec0588b4465b96c28a6e 422 Gene3D G3DSA:3.20.20.70 15 200 1.5E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS10960 f018c6cd18adec0588b4465b96c28a6e 422 Pfam PF01136 Peptidase family U32 90 321 9.8E-86 T 28-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CWR44_RS10960 f018c6cd18adec0588b4465b96c28a6e 422 Pfam PF16325 Peptidase family U32 C-terminal domain 338 418 3.2E-24 T 28-03-2018 IPR032525 Peptidase family U32, C-terminal CWR44_RS07550 fa131eda67cd5d3e134411195b0070d2 269 Pfam PF01513 ATP-NAD kinase 37 219 2.1E-26 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CWR44_RS07550 fa131eda67cd5d3e134411195b0070d2 269 Hamap MF_00361 NAD kinase [nadK]. 1 264 23.434 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CWR44_RS07550 fa131eda67cd5d3e134411195b0070d2 269 Gene3D G3DSA:3.40.50.10330 1 122 1.5E-23 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CWR44_RS07550 fa131eda67cd5d3e134411195b0070d2 269 Gene3D G3DSA:2.60.200.30 123 241 1.6E-24 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CWR44_RS07550 fa131eda67cd5d3e134411195b0070d2 269 SUPERFAMILY SSF111331 22 262 5.89E-63 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CWR44_RS09925 7dbe2e7000262be24df3ba997911f7b3 213 Pfam PF01895 PhoU domain 121 202 1.9E-15 T 28-03-2018 IPR026022 PhoU domain CWR44_RS09925 7dbe2e7000262be24df3ba997911f7b3 213 Pfam PF01895 PhoU domain 19 105 1.3E-18 T 28-03-2018 IPR026022 PhoU domain CWR44_RS09925 7dbe2e7000262be24df3ba997911f7b3 213 Gene3D G3DSA:1.20.58.220 114 213 2.3E-19 T 28-03-2018 CWR44_RS09925 7dbe2e7000262be24df3ba997911f7b3 213 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 210 7.5E-65 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CWR44_RS09925 7dbe2e7000262be24df3ba997911f7b3 213 SUPERFAMILY SSF109755 6 212 2.51E-53 T 28-03-2018 CWR44_RS09925 7dbe2e7000262be24df3ba997911f7b3 213 Gene3D G3DSA:1.20.58.220 1 113 6.0E-22 T 28-03-2018 CWR44_RS09925 7dbe2e7000262be24df3ba997911f7b3 213 PIRSF PIRSF003107 1 213 3.5E-64 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CWR44_RS07855 7ab0abf1d2efe456d0142841805d3d90 494 PIRSF PIRSF000485 7 472 1.7E-167 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CWR44_RS07855 7ab0abf1d2efe456d0142841805d3d90 494 Pfam PF13537 Glutamine amidotransferase domain 93 209 3.6E-20 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CWR44_RS07855 7ab0abf1d2efe456d0142841805d3d90 494 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 11 457 6.2E-145 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CWR44_RS07855 7ab0abf1d2efe456d0142841805d3d90 494 SUPERFAMILY SSF56235 11 234 1.63E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS07855 7ab0abf1d2efe456d0142841805d3d90 494 SUPERFAMILY SSF53271 249 464 5.51E-68 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWR44_RS07855 7ab0abf1d2efe456d0142841805d3d90 494 Gene3D G3DSA:3.40.50.2020 240 438 4.2E-32 T 28-03-2018 CWR44_RS07855 7ab0abf1d2efe456d0142841805d3d90 494 Pfam PF00156 Phosphoribosyl transferase domain 268 382 2.3E-9 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR44_RS07855 7ab0abf1d2efe456d0142841805d3d90 494 Gene3D G3DSA:3.60.20.10 11 239 5.6E-55 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS07855 7ab0abf1d2efe456d0142841805d3d90 494 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 10 456 43.984 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CWR44_RS01170 18ce470aee290be491e46698e90794c4 311 SUPERFAMILY SSF52768 9 310 1.62E-68 T 28-03-2018 CWR44_RS01170 18ce470aee290be491e46698e90794c4 311 Pfam PF00491 Arginase family 46 309 2.1E-47 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CWR44_RS01170 18ce470aee290be491e46698e90794c4 311 PIRSF PIRSF036979 20 311 2.4E-33 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CWR44_RS01170 18ce470aee290be491e46698e90794c4 311 Hamap MF_00737 Formimidoylglutamase [hutG]. 5 311 35.98 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CWR44_RS01170 18ce470aee290be491e46698e90794c4 311 Gene3D G3DSA:3.40.800.10 1 311 4.7E-68 T 28-03-2018 CWR44_RS01170 18ce470aee290be491e46698e90794c4 311 TIGRFAM TIGR01227 hutG: formimidoylglutamase 10 310 3.7E-110 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CWR44_RS12355 fe7d6368c98be844e6b8d5a77b492ef7 183 SUPERFAMILY SSF53098 2 169 1.97E-45 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS12355 fe7d6368c98be844e6b8d5a77b492ef7 183 Pfam PF00929 Exonuclease 6 157 4.3E-27 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR44_RS12355 fe7d6368c98be844e6b8d5a77b492ef7 183 Gene3D G3DSA:3.30.420.10 3 174 1.8E-36 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS12355 fe7d6368c98be844e6b8d5a77b492ef7 183 SMART SM00479 4 167 9.3E-32 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CWR44_RS12355 fe7d6368c98be844e6b8d5a77b492ef7 183 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 169 6.0E-23 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS08150 3a4e5cde77ac2624b819e785d10198c1 184 Pfam PF02620 Uncharacterized ACR, COG1399 55 180 1.2E-18 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CWR44_RS00590 feb1ec8fa69aeeaa424a43873ac44c16 586 SUPERFAMILY SSF52794 484 585 1.2E-18 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR44_RS00590 feb1ec8fa69aeeaa424a43873ac44c16 586 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 13 421 1.3E-75 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWR44_RS00590 feb1ec8fa69aeeaa424a43873ac44c16 586 Gene3D G3DSA:3.40.50.2300 478 585 8.2E-20 T 28-03-2018 CWR44_RS00590 feb1ec8fa69aeeaa424a43873ac44c16 586 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 423 579 3.1E-50 T 28-03-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWR44_RS00590 feb1ec8fa69aeeaa424a43873ac44c16 586 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 485 557 4.9E-10 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR44_RS00590 feb1ec8fa69aeeaa424a43873ac44c16 586 Pfam PF02378 Phosphotransferase system, EIIC 28 348 5.7E-70 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS00590 feb1ec8fa69aeeaa424a43873ac44c16 586 TIGRFAM TIGR00394 lac_pts_IIC: PTS system, lactose-specific IIC component 11 421 5.5E-222 T 28-03-2018 IPR004801 Phosphotransferase system, lactose-specific IIC component GO:0008982|GO:0016021|GO:0022869 KEGG: 00052+2.7.1.207|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWR44_RS00945 8cb3a63c915de76eca379f7be72c89e0 254 Gene3D G3DSA:3.40.630.30 107 252 8.9E-13 T 28-03-2018 CWR44_RS00945 8cb3a63c915de76eca379f7be72c89e0 254 Pfam PF00583 Acetyltransferase (GNAT) family 132 239 4.4E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS00945 8cb3a63c915de76eca379f7be72c89e0 254 SUPERFAMILY SSF55729 115 243 2.4E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS00220 008e37d474fcb225f807bfd80f0880d7 358 Pfam PF00472 RF-1 domain 210 318 2.0E-39 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CWR44_RS00220 008e37d474fcb225f807bfd80f0880d7 358 Pfam PF03462 PCRF domain 9 202 6.3E-73 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CWR44_RS00220 008e37d474fcb225f807bfd80f0880d7 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 354 39.964 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CWR44_RS00220 008e37d474fcb225f807bfd80f0880d7 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 354 3.6E-161 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CWR44_RS00220 008e37d474fcb225f807bfd80f0880d7 358 Gene3D G3DSA:3.30.160.20 208 313 9.9E-29 T 28-03-2018 CWR44_RS00220 008e37d474fcb225f807bfd80f0880d7 358 Gene3D G3DSA:1.20.58.410 2 94 2.9E-18 T 28-03-2018 CWR44_RS00220 008e37d474fcb225f807bfd80f0880d7 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CWR44_RS00220 008e37d474fcb225f807bfd80f0880d7 358 SMART SM00937 63 177 1.1E-61 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CWR44_RS00220 008e37d474fcb225f807bfd80f0880d7 358 SUPERFAMILY SSF75620 8 350 3.01E-132 T 28-03-2018 CWR44_RS00650 dedee49a3132162487648e1689d23e85 287 Gene3D G3DSA:3.40.50.300 1 258 6.2E-65 T 28-03-2018 CWR44_RS00650 dedee49a3132162487648e1689d23e85 287 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 279 3.3E-111 T 28-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 CWR44_RS00650 dedee49a3132162487648e1689d23e85 287 Pfam PF00005 ABC transporter 23 174 8.4E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS00650 dedee49a3132162487648e1689d23e85 287 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS00650 dedee49a3132162487648e1689d23e85 287 SUPERFAMILY SSF52540 3 237 8.2E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00650 dedee49a3132162487648e1689d23e85 287 SMART SM00382 32 223 4.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS02275 2f1012f50f447a9555d61f5260dfb3e9 386 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 231 244 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CWR44_RS02275 2f1012f50f447a9555d61f5260dfb3e9 386 Gene3D G3DSA:3.40.640.10 67 281 1.6E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS02275 2f1012f50f447a9555d61f5260dfb3e9 386 SUPERFAMILY SSF53383 1 380 2.2E-88 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS02275 2f1012f50f447a9555d61f5260dfb3e9 386 Pfam PF00155 Aminotransferase class I and II 30 377 4.8E-57 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR44_RS02275 2f1012f50f447a9555d61f5260dfb3e9 386 Gene3D G3DSA:3.90.1150.10 282 381 1.6E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 Pfam PF02811 PHP domain 4 119 1.5E-21 T 28-03-2018 IPR004013 PHP domain GO:0003824 CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 Gene3D G3DSA:1.10.150.280 724 828 5.9E-7 T 28-03-2018 CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 Gene3D G3DSA:2.40.50.140 895 990 3.6E-10 T 28-03-2018 CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 Pfam PF14579 Helix-hairpin-helix motif 744 831 1.4E-23 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 Pfam PF01336 OB-fold nucleic acid binding domain 921 986 2.0E-6 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 SMART SM00481 3 70 7.3E-16 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 SUPERFAMILY SSF89550 2 83 2.55E-9 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 SUPERFAMILY SSF89550 119 146 2.55E-9 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 251 669 1.6E-165 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 Gene3D G3DSA:3.20.20.140 1 495 1.2E-24 T 28-03-2018 CWR44_RS11375 039ff54231099683a05030f3ba0f9b0e 1067 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 128 949 2.1E-264 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS10585 ce5b8d8606f6d1632a031908876c2b20 276 Pfam PF03099 Biotin/lipoate A/B protein ligase family 51 188 3.3E-27 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWR44_RS10585 ce5b8d8606f6d1632a031908876c2b20 276 SUPERFAMILY SSF55681 4 276 2.73E-65 T 28-03-2018 CWR44_RS10585 ce5b8d8606f6d1632a031908876c2b20 276 Gene3D G3DSA:3.30.930.10 2 276 5.8E-58 T 28-03-2018 CWR44_RS10585 ce5b8d8606f6d1632a031908876c2b20 276 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 2 276 67.427 T 28-03-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CWR44_RS12690 b42c8d7b4a36748e1cd0332710403ac4 212 SMART SM00881 81 182 3.8E-16 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CWR44_RS12690 b42c8d7b4a36748e1cd0332710403ac4 212 Pfam PF02629 CoA binding domain 86 180 7.0E-24 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CWR44_RS12690 b42c8d7b4a36748e1cd0332710403ac4 212 SUPERFAMILY SSF46785 9 79 3.99E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12690 b42c8d7b4a36748e1cd0332710403ac4 212 SUPERFAMILY SSF51735 85 209 3.15E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS12690 b42c8d7b4a36748e1cd0332710403ac4 212 Gene3D G3DSA:3.40.50.720 79 210 1.9E-16 T 28-03-2018 CWR44_RS12690 b42c8d7b4a36748e1cd0332710403ac4 212 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 211 37.131 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CWR44_RS12690 b42c8d7b4a36748e1cd0332710403ac4 212 Gene3D G3DSA:1.10.10.10 6 75 1.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12690 b42c8d7b4a36748e1cd0332710403ac4 212 Pfam PF06971 Putative DNA-binding protein N-terminus 7 55 4.7E-19 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CWR44_RS01340 245af45aebdd5923253c48a06f6f09b4 562 PIRSF PIRSF032341 1 562 1.5E-222 T 28-03-2018 IPR016993 Predicted glycerophosphotransferase, SA2157 type CWR44_RS01340 245af45aebdd5923253c48a06f6f09b4 562 SUPERFAMILY SSF53756 345 491 7.74E-9 T 28-03-2018 CWR44_RS01340 245af45aebdd5923253c48a06f6f09b4 562 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 226 530 1.6E-44 T 28-03-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 CWR44_RS06565 7ad5f4d6626ab90a920e2f753a6cad6e 238 Pfam PF04055 Radical SAM superfamily 29 124 5.1E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS06565 7ad5f4d6626ab90a920e2f753a6cad6e 238 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 4 238 8.3E-114 T 28-03-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CWR44_RS06565 7ad5f4d6626ab90a920e2f753a6cad6e 238 Pfam PF13353 4Fe-4S single cluster domain 16 119 2.8E-10 T 28-03-2018 CWR44_RS06565 7ad5f4d6626ab90a920e2f753a6cad6e 238 PIRSF PIRSF000370 3 238 3.7E-51 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CWR44_RS06565 7ad5f4d6626ab90a920e2f753a6cad6e 238 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 5 235 34.197 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CWR44_RS06565 7ad5f4d6626ab90a920e2f753a6cad6e 238 Gene3D G3DSA:3.80.30.20 22 215 2.5E-16 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CWR44_RS06565 7ad5f4d6626ab90a920e2f753a6cad6e 238 SUPERFAMILY SSF102114 24 181 1.01E-13 T 28-03-2018 CWR44_RS12795 41585fa90c8c1b8300b3adfb03745487 151 Hamap MF_00745 Protein SprT-like. 4 147 38.687 T 28-03-2018 IPR023524 Uncharacterised protein family SprT-like CWR44_RS12795 41585fa90c8c1b8300b3adfb03745487 151 SMART SM00731 4 147 5.9E-54 T 28-03-2018 IPR006640 SprT-like CWR44_RS12795 41585fa90c8c1b8300b3adfb03745487 151 Pfam PF10263 SprT-like family 7 97 1.3E-11 T 28-03-2018 IPR006640 SprT-like CWR44_RS12795 41585fa90c8c1b8300b3adfb03745487 151 Pfam PF17283 SprT-like zinc ribbon domain 112 147 7.5E-8 T 28-03-2018 IPR035240 SprT-like, zinc ribbon domain CWR44_RS07375 eb4e9bb1df45480be35f01abf9cf0040 400 SUPERFAMILY SSF52402 2 164 7.28E-46 T 28-03-2018 CWR44_RS07375 eb4e9bb1df45480be35f01abf9cf0040 400 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 115 126 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS07375 eb4e9bb1df45480be35f01abf9cf0040 400 TIGRFAM TIGR00032 argG: argininosuccinate synthase 4 390 1.9E-156 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS07375 eb4e9bb1df45480be35f01abf9cf0040 400 Pfam PF00764 Arginosuccinate synthase 6 389 5.9E-167 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS07375 eb4e9bb1df45480be35f01abf9cf0040 400 Gene3D G3DSA:3.40.50.620 1 160 3.6E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS07375 eb4e9bb1df45480be35f01abf9cf0040 400 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 8 16 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS07375 eb4e9bb1df45480be35f01abf9cf0040 400 Hamap MF_00005 Argininosuccinate synthase [argG]. 2 395 52.445 T 28-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS07375 eb4e9bb1df45480be35f01abf9cf0040 400 Gene3D G3DSA:1.20.5.470 362 394 2.4E-9 T 28-03-2018 CWR44_RS07375 eb4e9bb1df45480be35f01abf9cf0040 400 SUPERFAMILY SSF69864 169 394 1.83E-90 T 28-03-2018 CWR44_RS07375 eb4e9bb1df45480be35f01abf9cf0040 400 Gene3D G3DSA:3.90.1260.10 161 351 3.2E-83 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CWR44_RS05725 116559ea2948aa29d503ec323514011f 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 46 2.7E-4 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWR44_RS05725 116559ea2948aa29d503ec323514011f 138 SUPERFAMILY SSF54593 12 120 7.52E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS05725 116559ea2948aa29d503ec323514011f 138 Gene3D G3DSA:3.10.180.10 8 125 1.2E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS00825 4e548b0fec854c07b8af328f447ee7c5 287 SUPERFAMILY SSF103481 193 276 3.92E-8 T 28-03-2018 CWR44_RS00825 4e548b0fec854c07b8af328f447ee7c5 287 SUPERFAMILY SSF103481 43 142 6.02E-6 T 28-03-2018 CWR44_RS00825 4e548b0fec854c07b8af328f447ee7c5 287 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 4 284 2.1E-100 T 28-03-2018 CWR44_RS00825 4e548b0fec854c07b8af328f447ee7c5 287 Pfam PF06800 Sugar transport protein 7 284 1.5E-101 T 28-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 Gene3D G3DSA:1.10.1060.10 4 153 5.5E-38 T 28-03-2018 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 5 483 1.2E-184 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 SUPERFAMILY SSF51971 154 416 1.12E-56 T 28-03-2018 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 Gene3D G3DSA:3.50.50.60 363 483 2.3E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 140 6.5E-23 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 PRINTS PR00419 Adrenodoxin reductase family signature 177 190 5.1E-22 T 28-03-2018 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 PRINTS PR00419 Adrenodoxin reductase family signature 219 229 5.1E-22 T 28-03-2018 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 PRINTS PR00419 Adrenodoxin reductase family signature 154 176 5.1E-22 T 28-03-2018 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 PRINTS PR00419 Adrenodoxin reductase family signature 293 307 5.1E-22 T 28-03-2018 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 SUPERFAMILY SSF46548 7 163 2.46E-30 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 Gene3D G3DSA:3.40.50.720 154 249 9.6E-19 T 28-03-2018 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 154 470 5.6E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 Gene3D G3DSA:3.50.50.60 250 337 1.0E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS05165 f40c6eeeabc1e6c135cf5461a7e475ca 487 SUPERFAMILY SSF51971 393 482 8.12E-10 T 28-03-2018 CWR44_RS04210 3afb4eb37c930c42048be0d51ab14d36 224 Gene3D G3DSA:1.10.10.10 5 68 5.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04210 3afb4eb37c930c42048be0d51ab14d36 224 Gene3D G3DSA:3.30.420.10 69 217 1.2E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS04210 3afb4eb37c930c42048be0d51ab14d36 224 Pfam PF13610 DDE domain 72 203 1.1E-38 T 28-03-2018 IPR032874 DDE domain CWR44_RS04210 3afb4eb37c930c42048be0d51ab14d36 224 SUPERFAMILY SSF53098 70 216 4.8E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS04190 3afb4eb37c930c42048be0d51ab14d36 224 Gene3D G3DSA:1.10.10.10 5 68 5.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04190 3afb4eb37c930c42048be0d51ab14d36 224 Gene3D G3DSA:3.30.420.10 69 217 1.2E-16 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS04190 3afb4eb37c930c42048be0d51ab14d36 224 Pfam PF13610 DDE domain 72 203 1.1E-38 T 28-03-2018 IPR032874 DDE domain CWR44_RS04190 3afb4eb37c930c42048be0d51ab14d36 224 SUPERFAMILY SSF53098 70 216 4.8E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS01785 48a546846396f56b6e67ab6f2e84b217 226 Gene3D G3DSA:3.40.50.2300 3 121 3.0E-22 T 28-03-2018 CWR44_RS01785 48a546846396f56b6e67ab6f2e84b217 226 SUPERFAMILY SSF46894 120 220 8.5E-33 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS01785 48a546846396f56b6e67ab6f2e84b217 226 SUPERFAMILY SSF52172 5 173 6.83E-27 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS01785 48a546846396f56b6e67ab6f2e84b217 226 SMART SM00448 3 113 4.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS01785 48a546846396f56b6e67ab6f2e84b217 226 SMART SM00862 143 219 1.4E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS01785 48a546846396f56b6e67ab6f2e84b217 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 1.0E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS01785 48a546846396f56b6e67ab6f2e84b217 226 Pfam PF00072 Response regulator receiver domain 5 113 3.6E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS01785 48a546846396f56b6e67ab6f2e84b217 226 Gene3D G3DSA:1.10.10.10 122 226 6.7E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11785 bf1bddbede9e9c72686635c7cc339f3c 121 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 113 1.6E-24 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CWR44_RS11785 bf1bddbede9e9c72686635c7cc339f3c 121 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 118 17.281 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CWR44_RS12705 17d59f7e429fbd5fb77a439e72ea6da3 154 Gene3D G3DSA:3.40.630.30 3 154 3.0E-30 T 28-03-2018 CWR44_RS12705 17d59f7e429fbd5fb77a439e72ea6da3 154 Pfam PF00583 Acetyltransferase (GNAT) family 22 129 5.0E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS12705 17d59f7e429fbd5fb77a439e72ea6da3 154 SUPERFAMILY SSF55729 10 152 3.65E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS12705 17d59f7e429fbd5fb77a439e72ea6da3 154 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 18 148 1.4E-34 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CWR44_RS08240 b18b0cfdea0b33441af3fd1d0db96aae 193 Gene3D G3DSA:3.90.950.10 1 193 7.9E-71 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CWR44_RS08240 b18b0cfdea0b33441af3fd1d0db96aae 193 Pfam PF01725 Ham1 family 4 187 1.6E-58 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CWR44_RS08240 b18b0cfdea0b33441af3fd1d0db96aae 193 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 191 46.616 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CWR44_RS08240 b18b0cfdea0b33441af3fd1d0db96aae 193 SUPERFAMILY SSF52972 1 190 1.49E-65 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CWR44_RS08240 b18b0cfdea0b33441af3fd1d0db96aae 193 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 189 4.2E-67 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CWR44_RS01025 5160291cf8c75b308ef9c9f8ad0a41ef 103 Pfam PF00893 Small Multidrug Resistance protein 1 93 4.1E-26 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CWR44_RS01025 5160291cf8c75b308ef9c9f8ad0a41ef 103 SUPERFAMILY SSF103481 4 101 1.83E-15 T 28-03-2018 CWR44_RS12010 b4cf93ca81ecb50383469545f7342ad6 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS12010 b4cf93ca81ecb50383469545f7342ad6 240 PIRSF PIRSF039085 1 240 3.3E-116 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CWR44_RS12010 b4cf93ca81ecb50383469545f7342ad6 240 SUPERFAMILY SSF52540 1 235 4.72E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS12010 b4cf93ca81ecb50383469545f7342ad6 240 Pfam PF00005 ABC transporter 17 165 8.0E-40 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS12010 b4cf93ca81ecb50383469545f7342ad6 240 SMART SM00382 26 221 1.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS12010 b4cf93ca81ecb50383469545f7342ad6 240 Gene3D G3DSA:3.40.50.300 1 239 8.1E-81 T 28-03-2018 CWR44_RS03390 bb8abe3395c3dba16a4f0a8bc44ccbad 303 Gene3D G3DSA:3.40.190.10 2 107 2.7E-7 T 28-03-2018 CWR44_RS03390 bb8abe3395c3dba16a4f0a8bc44ccbad 303 Pfam PF09084 NMT1/THI5 like 13 230 9.7E-57 T 28-03-2018 IPR015168 SsuA/THI5-like CWR44_RS03390 bb8abe3395c3dba16a4f0a8bc44ccbad 303 Gene3D G3DSA:3.40.190.10 111 300 2.4E-18 T 28-03-2018 CWR44_RS03390 bb8abe3395c3dba16a4f0a8bc44ccbad 303 SUPERFAMILY SSF53850 8 231 3.36E-30 T 28-03-2018 CWR44_RS06800 504ac01b5d734ad8a2659ca10f439d06 192 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 132 187 1.5E-27 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CWR44_RS06800 504ac01b5d734ad8a2659ca10f439d06 192 Gene3D G3DSA:3.30.160.100 2 100 1.6E-29 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR44_RS06800 504ac01b5d734ad8a2659ca10f439d06 192 SUPERFAMILY SSF69754 4 113 5.36E-32 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR44_RS06800 504ac01b5d734ad8a2659ca10f439d06 192 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 4 101 3.2E-30 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR44_RS06800 504ac01b5d734ad8a2659ca10f439d06 192 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 2 191 25.497 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CWR44_RS06800 504ac01b5d734ad8a2659ca10f439d06 192 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 96 3.1E-27 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CWR44_RS01970 22c031a463d971b100688d61a6fc2f7d 204 Pfam PF09335 SNARE associated Golgi protein 30 160 7.7E-23 T 28-03-2018 IPR032816 SNARE associated Golgi protein CWR44_RS10235 cd1b92b8e771089582d84248ea49296f 228 SUPERFAMILY SSF158499 125 191 1.12E-19 T 28-03-2018 IPR006343 DnaD domain CWR44_RS10235 cd1b92b8e771089582d84248ea49296f 228 Gene3D G3DSA:1.10.10.630 120 197 7.1E-22 T 28-03-2018 IPR034829 DnaD-like domain CWR44_RS10235 cd1b92b8e771089582d84248ea49296f 228 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 125 194 1.8E-22 T 28-03-2018 IPR006343 DnaD domain CWR44_RS10235 cd1b92b8e771089582d84248ea49296f 228 Pfam PF07261 Replication initiation and membrane attachment 126 196 2.6E-20 T 28-03-2018 IPR006343 DnaD domain CWR44_RS01795 580bb060d936562b3a656d1a3ee0f15b 264 Pfam PF03649 Uncharacterised protein family (UPF0014) 4 241 7.8E-66 T 28-03-2018 IPR005226 UPF0014 family CWR44_RS01795 580bb060d936562b3a656d1a3ee0f15b 264 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 1 247 9.5E-67 T 28-03-2018 IPR005226 UPF0014 family CWR44_RS01140 599eda454659d3e40cbddc3fe8ff4dcf 172 SUPERFAMILY SSF55961 6 163 4.45E-38 T 28-03-2018 CWR44_RS01140 599eda454659d3e40cbddc3fe8ff4dcf 172 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 21 162 3.6E-25 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CWR44_RS01140 599eda454659d3e40cbddc3fe8ff4dcf 172 Gene3D G3DSA:3.30.530.20 11 170 1.4E-19 T 28-03-2018 IPR023393 START-like domain CWR44_RS00820 4b5c7d54435e60442f5c4741249af510 290 Gene3D G3DSA:3.40.630.30 115 289 1.2E-12 T 28-03-2018 CWR44_RS00820 4b5c7d54435e60442f5c4741249af510 290 Pfam PF00583 Acetyltransferase (GNAT) family 169 272 4.5E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS00820 4b5c7d54435e60442f5c4741249af510 290 SUPERFAMILY SSF55729 48 281 1.34E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS02865 0096d6c6ded911e88a346621055bba30 137 Pfam PF08863 YolD-like protein 43 137 5.3E-24 T 28-03-2018 IPR014962 YolD-like protein CWR44_RS07555 6a097e8629bc0eb6a562f3522781dda9 287 Gene3D G3DSA:3.30.2350.10 74 287 3.9E-52 T 28-03-2018 CWR44_RS07555 6a097e8629bc0eb6a562f3522781dda9 287 SUPERFAMILY SSF55120 69 278 1.76E-54 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS07555 6a097e8629bc0eb6a562f3522781dda9 287 Pfam PF00849 RNA pseudouridylate synthase 84 231 2.2E-23 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS03740 c1008a4c3f49382c637a2d588118e60d 178 SUPERFAMILY SSF54593 4 155 4.3E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS03740 c1008a4c3f49382c637a2d588118e60d 178 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 126 1.7E-6 T 28-03-2018 CWR44_RS03740 c1008a4c3f49382c637a2d588118e60d 178 Gene3D G3DSA:3.10.180.10 3 176 2.9E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS08395 e23cc28bf3e46c43f1beab3c41ac7ebd 305 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS08395 e23cc28bf3e46c43f1beab3c41ac7ebd 305 Gene3D G3DSA:3.30.2350.10 80 304 1.9E-70 T 28-03-2018 CWR44_RS08395 e23cc28bf3e46c43f1beab3c41ac7ebd 305 SUPERFAMILY SSF55120 74 300 4.32E-77 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS08395 e23cc28bf3e46c43f1beab3c41ac7ebd 305 SUPERFAMILY SSF55174 15 114 3.4E-16 T 28-03-2018 CWR44_RS08395 e23cc28bf3e46c43f1beab3c41ac7ebd 305 Gene3D G3DSA:3.10.290.10 1 73 7.1E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS08395 e23cc28bf3e46c43f1beab3c41ac7ebd 305 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 300 4.9E-97 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS08395 e23cc28bf3e46c43f1beab3c41ac7ebd 305 Pfam PF00849 RNA pseudouridylate synthase 90 242 5.2E-35 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS08395 e23cc28bf3e46c43f1beab3c41ac7ebd 305 Pfam PF01479 S4 domain 16 62 2.5E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS08395 e23cc28bf3e46c43f1beab3c41ac7ebd 305 SMART SM00363 16 75 2.1E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS06605 a897c9adc7210bbf48cd3fd46246f744 334 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 299 2.4E-68 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CWR44_RS06605 a897c9adc7210bbf48cd3fd46246f744 334 SUPERFAMILY SSF50891 200 305 1.82E-5 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS06605 a897c9adc7210bbf48cd3fd46246f744 334 SMART SM00797 24 316 1.4E-100 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CWR44_RS04875 22694c2fdcb71a5fd7eb0271a3c5efe8 259 Gene3D G3DSA:3.90.850.10 1 259 1.7E-21 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR44_RS04875 22694c2fdcb71a5fd7eb0271a3c5efe8 259 SUPERFAMILY SSF56529 6 258 1.98E-48 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CWR44_RS05980 5db84e02e5b53fa4bcd35e5325a77f3f 178 Gene3D G3DSA:3.40.50.360 1 178 1.4E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS05980 5db84e02e5b53fa4bcd35e5325a77f3f 178 SUPERFAMILY SSF52218 2 177 1.39E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS05980 5db84e02e5b53fa4bcd35e5325a77f3f 178 Pfam PF03358 NADPH-dependent FMN reductase 2 110 1.3E-17 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CWR44_RS06190 a7a3e5904f51a92838e45564bf63e290 413 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 67 76 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR44_RS06190 a7a3e5904f51a92838e45564bf63e290 413 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 103 142 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR44_RS06190 a7a3e5904f51a92838e45564bf63e290 413 SUPERFAMILY SSF55031 257 320 2.09E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS06190 a7a3e5904f51a92838e45564bf63e290 413 SUPERFAMILY SSF55031 176 219 2.09E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS06190 a7a3e5904f51a92838e45564bf63e290 413 Pfam PF01546 Peptidase family M20/M25/M40 69 405 1.8E-37 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS06190 a7a3e5904f51a92838e45564bf63e290 413 SUPERFAMILY SSF53187 325 409 3.01E-61 T 28-03-2018 CWR44_RS06190 a7a3e5904f51a92838e45564bf63e290 413 SUPERFAMILY SSF53187 7 176 3.01E-61 T 28-03-2018 CWR44_RS06190 a7a3e5904f51a92838e45564bf63e290 413 Gene3D G3DSA:3.40.630.10 5 309 2.0E-64 T 28-03-2018 CWR44_RS06190 a7a3e5904f51a92838e45564bf63e290 413 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 11 398 2.5E-92 T 28-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CWR44_RS06190 a7a3e5904f51a92838e45564bf63e290 413 Pfam PF07687 Peptidase dimerisation domain 173 311 7.9E-24 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS01515 e27851caeca64db6ab61c782406fcec7 314 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 87 120 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR44_RS01515 e27851caeca64db6ab61c782406fcec7 314 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 8 241 1.3E-83 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR44_RS01515 e27851caeca64db6ab61c782406fcec7 314 SUPERFAMILY SSF53790 7 241 5.1E-61 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS01515 e27851caeca64db6ab61c782406fcec7 314 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 8 217 8.1E-46 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS01515 e27851caeca64db6ab61c782406fcec7 314 Gene3D G3DSA:3.30.950.10 132 269 1.6E-22 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS01515 e27851caeca64db6ab61c782406fcec7 314 Gene3D G3DSA:3.40.1010.10 7 131 2.6E-34 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS05830 9f8222b855e73394cc7c42a964412e8d 497 SUPERFAMILY SSF53756 170 492 1.1E-49 T 28-03-2018 CWR44_RS05830 9f8222b855e73394cc7c42a964412e8d 497 Pfam PF00534 Glycosyl transferases group 1 318 472 1.9E-32 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CWR44_RS05830 9f8222b855e73394cc7c42a964412e8d 497 Gene3D G3DSA:3.40.50.2000 320 487 7.4E-32 T 28-03-2018 CWR44_RS03035 f636b0635bf42a3329d362b34e081a99 275 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 24 275 1.1E-79 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CWR44_RS03035 f636b0635bf42a3329d362b34e081a99 275 SUPERFAMILY SSF161098 79 265 1.01E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03035 f636b0635bf42a3329d362b34e081a99 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 273 4.6E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03035 f636b0635bf42a3329d362b34e081a99 275 Gene3D G3DSA:1.10.3720.10 23 275 1.8E-26 T 28-03-2018 CWR44_RS07420 820d2bce7ca5f0a06f74cd593f6a293c 133 Pfam PF07457 Protein of unknown function (DUF1516) 2 118 5.5E-33 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 CWR44_RS07420 820d2bce7ca5f0a06f74cd593f6a293c 133 Hamap MF_01536 UPF0344 protein . 1 128 14.345 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 CWR44_RS07420 820d2bce7ca5f0a06f74cd593f6a293c 133 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 124 2.0E-56 T 28-03-2018 IPR010899 Protein of unknown function UPF0344 CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 Gene3D G3DSA:3.10.580.10 260 383 2.1E-25 T 28-03-2018 CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 Gene3D G3DSA:3.40.50.300 1 259 1.0E-78 T 28-03-2018 CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 SUPERFAMILY SSF54631 250 373 1.48E-24 T 28-03-2018 CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 SMART SM00382 28 214 1.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 13 371 3.5E-137 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 Pfam PF00571 CBS domain 252 301 1.4E-6 T 28-03-2018 IPR000644 CBS domain CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 Pfam PF00571 CBS domain 315 363 8.6E-8 T 28-03-2018 IPR000644 CBS domain CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 Pfam PF00005 ABC transporter 19 164 6.6E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 SUPERFAMILY SSF52540 3 241 6.26E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 SMART SM00116 318 366 7.5E-5 T 28-03-2018 IPR000644 CBS domain CWR44_RS01750 76ab60d9d21ca989716f6aeb7352b460 435 SMART SM00116 258 306 6.3E-7 T 28-03-2018 IPR000644 CBS domain CWR44_RS11565 df10aafef3f783a4237938b325db3615 168 SUPERFAMILY SSF58104 39 134 7.59E-5 T 28-03-2018 CWR44_RS11565 df10aafef3f783a4237938b325db3615 168 Pfam PF06103 Bacterial protein of unknown function (DUF948) 7 94 5.0E-29 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 CWR44_RS11565 df10aafef3f783a4237938b325db3615 168 Gene3D G3DSA:3.90.20.10 26 165 1.5E-8 T 28-03-2018 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 SMART SM01192 141 431 9.1E-214 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 Hamap MF_00318 Enolase [eno]. 2 417 44.781 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 PIRSF PIRSF001400 1 431 3.7E-188 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 SUPERFAMILY SSF51604 142 431 1.56E-126 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 ProSitePatterns PS00164 Enolase signature. 340 353 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 431 5.8E-209 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 PRINTS PR00148 Enolase signature 109 125 3.7E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 PRINTS PR00148 Enolase signature 37 51 3.7E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 PRINTS PR00148 Enolase signature 317 328 3.7E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 PRINTS PR00148 Enolase signature 163 176 3.7E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 PRINTS PR00148 Enolase signature 340 354 3.7E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 PRINTS PR00148 Enolase signature 369 386 3.7E-47 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 SMART SM01193 4 136 5.7E-97 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 Pfam PF03952 Enolase, N-terminal domain 4 136 6.3E-61 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 Pfam PF00113 Enolase, C-terminal TIM barrel domain 143 429 6.7E-131 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 Gene3D G3DSA:3.20.20.120 130 434 1.1E-99 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 Gene3D G3DSA:3.30.390.10 3 127 4.7E-54 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS06945 6ea02194b8349e7d51e231b2ff0d4302 434 SUPERFAMILY SSF54826 4 143 1.17E-58 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS12375 141447a7103d4f1f8bc7f56b707cb199 330 Pfam PF00781 Diacylglycerol kinase catalytic domain 6 128 4.2E-34 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CWR44_RS12375 141447a7103d4f1f8bc7f56b707cb199 330 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 4 295 9.6E-93 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CWR44_RS12375 141447a7103d4f1f8bc7f56b707cb199 330 SMART SM00046 4 132 1.5E-9 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CWR44_RS12375 141447a7103d4f1f8bc7f56b707cb199 330 SUPERFAMILY SSF111331 4 297 1.57E-80 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CWR44_RS12375 141447a7103d4f1f8bc7f56b707cb199 330 Gene3D G3DSA:3.40.50.10330 1 132 1.2E-33 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CWR44_RS10725 1e6d0453c7e4e3e25c46232327ea3147 229 SUPERFAMILY SSF53335 17 138 6.92E-9 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS10725 1e6d0453c7e4e3e25c46232327ea3147 229 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 20 222 1.4E-71 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CWR44_RS10725 1e6d0453c7e4e3e25c46232327ea3147 229 PIRSF PIRSF018637 2 228 1.6E-76 T 28-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CWR44_RS10725 1e6d0453c7e4e3e25c46232327ea3147 229 Gene3D G3DSA:3.40.50.150 2 164 4.1E-13 T 28-03-2018 CWR44_RS08050 41c919a35bc9396fd3db7b52732fcd5c 203 SUPERFAMILY SSF142913 2 203 2.41E-76 T 28-03-2018 CWR44_RS08050 41c919a35bc9396fd3db7b52732fcd5c 203 Hamap MF_01851 UPF0637 protein . 5 203 37.713 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CWR44_RS08050 41c919a35bc9396fd3db7b52732fcd5c 203 Pfam PF06335 Protein of unknown function (DUF1054) 6 202 5.7E-78 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CWR44_RS08050 41c919a35bc9396fd3db7b52732fcd5c 203 PIRSF PIRSF021332 1 203 8.5E-87 T 28-03-2018 IPR009403 Protein of unknown function UPF0637 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 Gene3D G3DSA:4.10.640.10 3 80 1.6E-35 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 3.5E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 3.5E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 3.5E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 3.5E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 Pfam PF01084 Ribosomal protein S18 23 73 1.8E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 SUPERFAMILY SSF46911 5 78 7.46E-32 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 TIGRFAM TIGR00165 S18: ribosomal protein bS18 11 78 2.6E-38 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 7 78 23.38 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 78 1.0E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04630 e1297b20755d46772fb7308522befd1e 80 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS07190 6f9b0d7c8d300cb35a6f04ab9b9dbfba 306 Pfam PF04055 Radical SAM superfamily 65 225 1.7E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS07190 6f9b0d7c8d300cb35a6f04ab9b9dbfba 306 Hamap MF_00206 Lipoyl synthase [lipA]. 1 297 148.117 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CWR44_RS07190 6f9b0d7c8d300cb35a6f04ab9b9dbfba 306 SMART SM00729 58 266 6.1E-16 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR44_RS07190 6f9b0d7c8d300cb35a6f04ab9b9dbfba 306 Gene3D G3DSA:3.20.20.70 3 290 1.4E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS07190 6f9b0d7c8d300cb35a6f04ab9b9dbfba 306 TIGRFAM TIGR00510 lipA: lipoyl synthase 2 294 1.6E-120 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CWR44_RS07190 6f9b0d7c8d300cb35a6f04ab9b9dbfba 306 PIRSF PIRSF005963 1 306 2.1E-135 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CWR44_RS07190 6f9b0d7c8d300cb35a6f04ab9b9dbfba 306 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 4 46 4.7E-11 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CWR44_RS07190 6f9b0d7c8d300cb35a6f04ab9b9dbfba 306 SUPERFAMILY SSF102114 28 292 1.7E-62 T 28-03-2018 CWR44_RS09585 aef26c65ae9ea6585442e5d625bd5c7c 169 SUPERFAMILY SSF52980 9 162 3.49E-44 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWR44_RS09585 aef26c65ae9ea6585442e5d625bd5c7c 169 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 169 41.109 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CWR44_RS09585 aef26c65ae9ea6585442e5d625bd5c7c 169 Gene3D G3DSA:3.40.1350.10 8 164 2.1E-43 T 28-03-2018 CWR44_RS09585 aef26c65ae9ea6585442e5d625bd5c7c 169 Pfam PF03838 Recombination protein U 7 161 3.5E-43 T 28-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CWR44_RS08075 55f532d67a7cc87b37d8480d68e6b1a1 161 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 1 160 2.0E-89 T 28-03-2018 IPR020229 Uncharacterised protein YlaL CWR44_RS11760 3c306c19a1932c50163d8025245003b0 158 Gene3D G3DSA:1.10.1740.10 1 72 1.8E-10 T 28-03-2018 CWR44_RS11760 3c306c19a1932c50163d8025245003b0 158 SUPERFAMILY SSF88946 3 86 8.24E-7 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS11760 3c306c19a1932c50163d8025245003b0 158 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 152 3.9E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS11760 3c306c19a1932c50163d8025245003b0 158 Gene3D G3DSA:1.10.10.10 81 158 7.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11760 3c306c19a1932c50163d8025245003b0 158 SUPERFAMILY SSF88659 111 154 3.79E-6 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS11760 3c306c19a1932c50163d8025245003b0 158 Pfam PF04542 Sigma-70 region 2 7 73 5.6E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS09625 16761a7c7d826b94a0d0261d717a3ddc 214 SUPERFAMILY SSF55620 27 213 3.78E-71 T 28-03-2018 CWR44_RS09625 16761a7c7d826b94a0d0261d717a3ddc 214 Pfam PF01227 GTP cyclohydrolase I 39 212 1.0E-71 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWR44_RS09625 16761a7c7d826b94a0d0261d717a3ddc 214 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 32 213 36.729 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWR44_RS09625 16761a7c7d826b94a0d0261d717a3ddc 214 Gene3D G3DSA:1.10.286.10 34 82 1.1E-16 T 28-03-2018 CWR44_RS09625 16761a7c7d826b94a0d0261d717a3ddc 214 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 92 108 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWR44_RS09625 16761a7c7d826b94a0d0261d717a3ddc 214 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 38 213 1.7E-69 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CWR44_RS09625 16761a7c7d826b94a0d0261d717a3ddc 214 Gene3D G3DSA:3.30.1130.10 83 214 1.2E-58 T 28-03-2018 CWR44_RS02775 cdbc14e2e1302b69078488902aab6a9b 149 Pfam PF12802 MarR family 31 89 6.7E-13 T 28-03-2018 CWR44_RS02775 cdbc14e2e1302b69078488902aab6a9b 149 SMART SM00347 26 131 1.8E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS02775 cdbc14e2e1302b69078488902aab6a9b 149 SUPERFAMILY SSF46785 11 132 5.29E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02775 cdbc14e2e1302b69078488902aab6a9b 149 Gene3D G3DSA:1.10.10.10 1 135 2.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11830 68119f249ba95c341283a3c9aab25f02 335 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 9 308 2.6E-79 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS11830 68119f249ba95c341283a3c9aab25f02 335 SUPERFAMILY SSF54826 1 111 1.71E-17 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS11830 68119f249ba95c341283a3c9aab25f02 335 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 334 27.139 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS11830 68119f249ba95c341283a3c9aab25f02 335 Gene3D G3DSA:3.30.390.10 1 127 9.4E-11 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CWR44_RS11830 68119f249ba95c341283a3c9aab25f02 335 Gene3D G3DSA:3.20.20.120 128 324 1.9E-19 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CWR44_RS11830 68119f249ba95c341283a3c9aab25f02 335 SUPERFAMILY SSF51604 133 322 1.97E-27 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CWR44_RS11830 68119f249ba95c341283a3c9aab25f02 335 Pfam PF13378 Enolase C-terminal domain-like 134 320 2.6E-10 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CWR44_RS12435 cece52792597853b6da588bfe372c62e 202 Hamap MF_01515 UPF0316 protein . 9 177 30.883 T 28-03-2018 IPR022930 Protein of unknown function UPF0316 CWR44_RS12435 cece52792597853b6da588bfe372c62e 202 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 117 169 3.0E-8 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CWR44_RS01585 15d5082bb17397152443a648da6aa633 266 SMART SM00062 41 261 2.4E-65 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR44_RS01585 15d5082bb17397152443a648da6aa633 266 SMART SM00079 41 260 0.005 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CWR44_RS01585 15d5082bb17397152443a648da6aa633 266 Gene3D G3DSA:3.40.190.10 146 255 1.2E-19 T 28-03-2018 CWR44_RS01585 15d5082bb17397152443a648da6aa633 266 Gene3D G3DSA:3.40.190.10 33 145 2.4E-33 T 28-03-2018 CWR44_RS01585 15d5082bb17397152443a648da6aa633 266 SUPERFAMILY SSF53850 1 261 2.66E-60 T 28-03-2018 CWR44_RS01585 15d5082bb17397152443a648da6aa633 266 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 260 1.2E-56 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR44_RS06025 5dabb1caf90074b123aa857e95f343ad 273 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 60 1.9E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS06025 5dabb1caf90074b123aa857e95f343ad 273 Gene3D G3DSA:1.10.10.10 1 81 2.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06025 5dabb1caf90074b123aa857e95f343ad 273 SUPERFAMILY SSF46785 2 108 2.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06025 5dabb1caf90074b123aa857e95f343ad 273 Pfam PF03466 LysR substrate binding domain 86 268 1.6E-18 T 28-03-2018 IPR005119 LysR, substrate-binding CWR44_RS06025 5dabb1caf90074b123aa857e95f343ad 273 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 16 27 2.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS06025 5dabb1caf90074b123aa857e95f343ad 273 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 37 2.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS06025 5dabb1caf90074b123aa857e95f343ad 273 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 48 2.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS06025 5dabb1caf90074b123aa857e95f343ad 273 Gene3D G3DSA:3.40.190.10 85 238 2.1E-12 T 28-03-2018 CWR44_RS06025 5dabb1caf90074b123aa857e95f343ad 273 SUPERFAMILY SSF53850 82 269 1.18E-19 T 28-03-2018 CWR44_RS01265 4ab85a357fa93124b5ffeeba7808cfa7 565 Pfam PF01609 Transposase DDE domain 264 515 2.2E-36 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS01265 4ab85a357fa93124b5ffeeba7808cfa7 565 Gene3D G3DSA:3.90.350.10 262 498 5.0E-6 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS01265 4ab85a357fa93124b5ffeeba7808cfa7 565 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS03950 90af8bf01ba927b01b287f8d5128e3d6 292 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 3 180 5.6E-41 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CWR44_RS03950 90af8bf01ba927b01b287f8d5128e3d6 292 Gene3D G3DSA:3.40.50.300 1 197 1.7E-29 T 28-03-2018 CWR44_RS03950 90af8bf01ba927b01b287f8d5128e3d6 292 SUPERFAMILY SSF90002 218 287 3.4E-8 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CWR44_RS03950 90af8bf01ba927b01b287f8d5128e3d6 292 Gene3D G3DSA:3.30.1220.10 198 291 1.5E-8 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CWR44_RS03950 90af8bf01ba927b01b287f8d5128e3d6 292 SUPERFAMILY SSF52540 2 179 1.08E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03950 90af8bf01ba927b01b287f8d5128e3d6 292 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 218 290 1.4E-9 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CWR44_RS09450 5e6638ab78f151cd8346806d256ee309 316 SUPERFAMILY SSF52980 10 209 2.52E-38 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWR44_RS09450 5e6638ab78f151cd8346806d256ee309 316 Pfam PF09588 YqaJ-like viral recombinase domain 19 155 6.2E-27 T 28-03-2018 IPR019080 YqaJ viral recombinase CWR44_RS09450 5e6638ab78f151cd8346806d256ee309 316 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 14 163 3.7E-34 T 28-03-2018 IPR017482 Putative phage-type endonuclease CWR44_RS09450 5e6638ab78f151cd8346806d256ee309 316 Gene3D G3DSA:3.90.320.10 14 220 1.1E-48 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CWR44_RS01190 eb9c79ecfb1329f63eb2e160215c2352 336 Pfam PF01263 Aldose 1-epimerase 13 332 1.4E-53 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CWR44_RS01190 eb9c79ecfb1329f63eb2e160215c2352 336 SUPERFAMILY SSF74650 5 334 1.7E-74 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CWR44_RS01190 eb9c79ecfb1329f63eb2e160215c2352 336 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 167 176 - T 28-03-2018 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 CWR44_RS01190 eb9c79ecfb1329f63eb2e160215c2352 336 Gene3D G3DSA:2.70.98.10 1 336 1.6E-62 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CWR44_RS04940 d5b2495d0dcaf851dfdcba984c6cde84 308 Pfam PF01381 Helix-turn-helix 8 55 1.4E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS04940 d5b2495d0dcaf851dfdcba984c6cde84 308 SMART SM00530 7 61 1.5E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS04940 d5b2495d0dcaf851dfdcba984c6cde84 308 SUPERFAMILY SSF47413 1 55 2.76E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS04940 d5b2495d0dcaf851dfdcba984c6cde84 308 Gene3D G3DSA:1.10.260.40 1 256 2.9E-13 T 28-03-2018 CWR44_RS06745 4cda32a0254dc3a9c3d8bb8eeaa25266 106 Gene3D G3DSA:3.40.30.10 2 103 1.4E-38 T 28-03-2018 CWR44_RS06745 4cda32a0254dc3a9c3d8bb8eeaa25266 106 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 4 102 6.7E-34 T 28-03-2018 IPR022551 Protein of unknown function DUF2847 CWR44_RS06745 4cda32a0254dc3a9c3d8bb8eeaa25266 106 SUPERFAMILY SSF52833 3 88 3.89E-8 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS06745 4cda32a0254dc3a9c3d8bb8eeaa25266 106 Pfam PF11009 Protein of unknown function (DUF2847) 4 101 2.1E-33 T 28-03-2018 IPR022551 Protein of unknown function DUF2847 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 Pfam PF07687 Peptidase dimerisation domain 187 274 1.4E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 SUPERFAMILY SSF55031 183 290 2.49E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 Pfam PF01546 Peptidase family M20/M25/M40 76 369 3.1E-20 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 369 7.3E-124 T 28-03-2018 IPR010162 Peptidase M20B, peptidase T-like CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 108 146 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 Gene3D G3DSA:3.30.70.360 187 284 1.7E-22 T 28-03-2018 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 Gene3D G3DSA:3.40.630.10 285 374 0.0047 T 28-03-2018 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 PIRSF PIRSF001123 4 103 3.9E-4 T 28-03-2018 IPR008007 Peptidase M42 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 PIRSF PIRSF001123 257 375 3.2E-6 T 28-03-2018 IPR008007 Peptidase M42 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 PIRSF PIRSF001123 102 193 1.7E-6 T 28-03-2018 IPR008007 Peptidase M42 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 SUPERFAMILY SSF53187 290 369 2.21E-59 T 28-03-2018 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 SUPERFAMILY SSF53187 5 181 2.21E-59 T 28-03-2018 CWR44_RS10480 ac7c93919ccd17f135e724110158d8d1 375 Gene3D G3DSA:3.40.630.10 1 186 5.0E-26 T 28-03-2018 CWR44_RS10100 3cdde8b1d27e275ee201d4caa3f30ecd 73 PIRSF PIRSF037262 2 72 3.5E-27 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 CWR44_RS10100 3cdde8b1d27e275ee201d4caa3f30ecd 73 Hamap MF_01538 UPF0346 protein . 2 70 20.348 T 28-03-2018 IPR010673 Protein of unknown function UPF0346 CWR44_RS10100 3cdde8b1d27e275ee201d4caa3f30ecd 73 Pfam PF06855 YozE SAM-like fold 5 68 1.6E-23 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS10100 3cdde8b1d27e275ee201d4caa3f30ecd 73 Gene3D G3DSA:1.10.150.260 5 69 2.6E-24 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS10100 3cdde8b1d27e275ee201d4caa3f30ecd 73 SUPERFAMILY SSF140652 4 71 3.27E-24 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS10915 6b55d3d68c2db497f7689b920ff74627 228 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 1 228 44.094 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS10915 6b55d3d68c2db497f7689b920ff74627 228 Pfam PF01048 Phosphorylase superfamily 2 225 1.0E-52 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWR44_RS10915 6b55d3d68c2db497f7689b920ff74627 228 SUPERFAMILY SSF53167 2 228 1.7E-71 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CWR44_RS10915 6b55d3d68c2db497f7689b920ff74627 228 Gene3D G3DSA:3.40.50.1580 1 228 7.1E-55 T 28-03-2018 CWR44_RS10915 6b55d3d68c2db497f7689b920ff74627 228 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 227 3.5E-85 T 28-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CWR44_RS05015 8cf72f9a5f4506252b2e482d4248de81 191 Pfam PF03592 Terminase small subunit 4 145 1.7E-33 T 28-03-2018 IPR005335 Terminase small subunit GO:0006323 CWR44_RS02060 a1f83bf6f2bb0fa9b56dde193ab00768 164 Gene3D G3DSA:3.40.630.30 1 164 9.9E-34 T 28-03-2018 CWR44_RS02060 a1f83bf6f2bb0fa9b56dde193ab00768 164 Pfam PF13420 Acetyltransferase (GNAT) domain 2 153 4.5E-25 T 28-03-2018 CWR44_RS02060 a1f83bf6f2bb0fa9b56dde193ab00768 164 SUPERFAMILY SSF55729 1 163 6.65E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 Gene3D G3DSA:3.40.50.300 779 1182 2.7E-30 T 28-03-2018 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 Gene3D G3DSA:1.20.5.320 629 759 0.012 T 28-03-2018 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 Gene3D G3DSA:3.40.50.300 1 181 1.4E-39 T 28-03-2018 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 SUPERFAMILY SSF75553 485 687 9.68E-54 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 SUPERFAMILY SSF57997 373 520 7.19E-5 T 28-03-2018 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 639 3.3E-31 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1179 22.709 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 Gene3D G3DSA:1.20.5.730 414 502 5.6E-6 T 28-03-2018 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 SUPERFAMILY SSF52540 3 215 4.87E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 SUPERFAMILY SSF52540 1076 1162 4.87E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1170 3.2E-57 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1177 0.0 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 Gene3D G3DSA:1.20.5.170 231 324 3.9E-4 T 28-03-2018 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 Gene3D G3DSA:1.10.287.510 325 413 1.2E-6 T 28-03-2018 CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 PIRSF PIRSF005719 1 1184 0.0 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein CWR44_RS08580 310a0d25efaf96db3b2a41d871c91e1b 1189 SMART SM00968 520 639 3.6E-41 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CWR44_RS00565 34d346bf6850efba53d30b9c81b3298a 516 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 47 492 6.1E-157 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CWR44_RS00565 34d346bf6850efba53d30b9c81b3298a 516 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 9 490 7.3E-185 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CWR44_RS00565 34d346bf6850efba53d30b9c81b3298a 516 ProSitePatterns PS01303 BCCT family of transporters signature. 313 322 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CWR44_RS03800 ea5d08b1549d89f13a4b732e5b8adc42 143 Gene3D G3DSA:1.10.1660.10 1 55 6.9E-16 T 28-03-2018 CWR44_RS03800 ea5d08b1549d89f13a4b732e5b8adc42 143 Gene3D G3DSA:1.10.1660.10 56 137 2.4E-7 T 28-03-2018 CWR44_RS03800 ea5d08b1549d89f13a4b732e5b8adc42 143 SMART SM00422 1 70 9.9E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS03800 ea5d08b1549d89f13a4b732e5b8adc42 143 Pfam PF13411 MerR HTH family regulatory protein 1 61 9.3E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS03800 ea5d08b1549d89f13a4b732e5b8adc42 143 SUPERFAMILY SSF46955 1 117 1.9E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 3.5E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 1.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 1.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 1.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 Gene3D G3DSA:3.40.50.2300 1 126 5.1E-30 T 28-03-2018 CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 Pfam PF00072 Response regulator receiver domain 4 116 6.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 SUPERFAMILY SSF52172 3 175 2.87E-32 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 SMART SM00448 2 116 3.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 Gene3D G3DSA:1.10.10.10 127 207 1.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11965 3fd1c2734ad096733caa0ed8a4dd1ab2 207 SMART SM00421 144 201 7.6E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS02525 29bdfbe044c187d181c44af55ea92048 157 SUPERFAMILY SSF54909 45 123 9.58E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CWR44_RS02525 29bdfbe044c187d181c44af55ea92048 157 Gene3D G3DSA:3.30.70.100 38 145 3.0E-19 T 28-03-2018 CWR44_RS02525 29bdfbe044c187d181c44af55ea92048 157 Pfam PF03992 Antibiotic biosynthesis monooxygenase 45 119 6.1E-12 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CWR44_RS05265 3c2c09509192a3f2f1d1d8a21ac77666 241 Gene3D G3DSA:3.40.50.150 6 240 3.7E-37 T 28-03-2018 CWR44_RS05265 3c2c09509192a3f2f1d1d8a21ac77666 241 Pfam PF05175 Methyltransferase small domain 19 171 6.8E-16 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CWR44_RS05265 3c2c09509192a3f2f1d1d8a21ac77666 241 SUPERFAMILY SSF53335 8 211 9.98E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 Gene3D G3DSA:3.40.50.720 1 234 3.8E-46 T 28-03-2018 CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 6.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 6.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 6.6E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 216 1.2E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 SUPERFAMILY SSF51735 2 233 2.49E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS08810 08c8b67e724fcc36f835caeae5f92101 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 230 9.7E-37 T 28-03-2018 CWR44_RS07185 cf4ace717690473adc758298e4262934 440 SUPERFAMILY SSF56300 1 257 2.33E-60 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS07185 cf4ace717690473adc758298e4262934 440 Gene3D G3DSA:3.60.21.10 1 268 2.8E-48 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS07185 cf4ace717690473adc758298e4262934 440 SUPERFAMILY SSF55816 285 437 4.19E-22 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07185 cf4ace717690473adc758298e4262934 440 Gene3D G3DSA:3.90.780.10 271 440 7.7E-23 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07185 cf4ace717690473adc758298e4262934 440 Pfam PF02872 5'-nucleotidase, C-terminal domain 285 404 3.9E-9 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07185 cf4ace717690473adc758298e4262934 440 PRINTS PR01607 Apyrase family signature 210 230 8.6E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07185 cf4ace717690473adc758298e4262934 440 PRINTS PR01607 Apyrase family signature 315 338 8.6E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07185 cf4ace717690473adc758298e4262934 440 PRINTS PR01607 Apyrase family signature 163 180 8.6E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07185 cf4ace717690473adc758298e4262934 440 PRINTS PR01607 Apyrase family signature 182 205 8.6E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07185 cf4ace717690473adc758298e4262934 440 PRINTS PR01607 Apyrase family signature 1 15 8.6E-18 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS07185 cf4ace717690473adc758298e4262934 440 Pfam PF00149 Calcineurin-like phosphoesterase 3 199 4.9E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR44_RS07185 cf4ace717690473adc758298e4262934 440 PIRSF PIRSF036361 1 440 2.6E-178 T 28-03-2018 IPR011240 Phosphoesterase-related protein YunD CWR44_RS05745 23cc282040cb00f6d9f1211d2f6ece3a 233 Gene3D G3DSA:3.40.50.1000 1 226 9.6E-27 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS05745 23cc282040cb00f6d9f1211d2f6ece3a 233 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 190 4.3E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CWR44_RS05745 23cc282040cb00f6d9f1211d2f6ece3a 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 192 1.0E-24 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS05745 23cc282040cb00f6d9f1211d2f6ece3a 233 SUPERFAMILY SSF56784 1 229 5.83E-38 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS03210 b83527bf86d381aaf47357e425993bad 202 Gene3D G3DSA:3.40.190.10 1 198 0.0016 T 28-03-2018 CWR44_RS10590 b6611208f354b6e5e0cfa803da1914cc 128 SMART SM00450 31 126 9.2E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS10590 b6611208f354b6e5e0cfa803da1914cc 128 SUPERFAMILY SSF52821 10 121 2.36E-30 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS10590 b6611208f354b6e5e0cfa803da1914cc 128 Gene3D G3DSA:3.40.250.10 27 128 5.0E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS10590 b6611208f354b6e5e0cfa803da1914cc 128 Pfam PF00581 Rhodanese-like domain 36 121 5.9E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CWR44_RS01955 14b2ddbc61a9acd54412f407d533f893 66 Gene3D G3DSA:3.10.20.30 1 66 1.8E-15 T 28-03-2018 IPR012675 Beta-grasp domain CWR44_RS01955 14b2ddbc61a9acd54412f407d533f893 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 5.9E-20 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis CWR44_RS01955 14b2ddbc61a9acd54412f407d533f893 66 Pfam PF02597 ThiS family 7 66 1.6E-8 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CWR44_RS01955 14b2ddbc61a9acd54412f407d533f893 66 SUPERFAMILY SSF54285 3 65 4.11E-15 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CWR44_RS11345 62feceb6bcc7f983087099f1a962d524 325 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CWR44_RS11345 62feceb6bcc7f983087099f1a962d524 325 Gene3D G3DSA:1.10.1200.80 250 325 1.7E-13 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CWR44_RS11345 62feceb6bcc7f983087099f1a962d524 325 Gene3D G3DSA:3.20.20.70 11 249 1.2E-34 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS11345 62feceb6bcc7f983087099f1a962d524 325 SUPERFAMILY SSF51395 13 318 5.0E-61 T 28-03-2018 CWR44_RS11345 62feceb6bcc7f983087099f1a962d524 325 Pfam PF01207 Dihydrouridine synthase (Dus) 15 317 1.1E-51 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CWR44_RS11345 62feceb6bcc7f983087099f1a962d524 325 PIRSF PIRSF006621 1 325 5.1E-87 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CWR44_RS03270 6b432f825f5938ef8f8879a7333671c8 261 Hamap MF_01830 UPF0317 protein . 7 261 51.921 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 CWR44_RS03270 6b432f825f5938ef8f8879a7333671c8 261 PIRSF PIRSF029755 1 261 2.0E-119 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 CWR44_RS03270 6b432f825f5938ef8f8879a7333671c8 261 Pfam PF07286 Protein of unknown function (DUF1445) 111 253 1.3E-64 T 28-03-2018 IPR009906 D-glutamate cyclase CWR44_RS03270 6b432f825f5938ef8f8879a7333671c8 261 Gene3D G3DSA:3.40.1640.10 197 261 7.0E-12 T 28-03-2018 CWR44_RS03270 6b432f825f5938ef8f8879a7333671c8 261 Gene3D G3DSA:3.40.1640.10 1 163 3.5E-68 T 28-03-2018 CWR44_RS03270 6b432f825f5938ef8f8879a7333671c8 261 SUPERFAMILY SSF160920 2 255 2.75E-113 T 28-03-2018 CWR44_RS01430 71f57e2666b402cbae0b42ef53d2aaf5 480 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS01430 71f57e2666b402cbae0b42ef53d2aaf5 480 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 468 2.2E-203 T 28-03-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 CWR44_RS01430 71f57e2666b402cbae0b42ef53d2aaf5 480 Pfam PF02378 Phosphotransferase system, EIIC 110 412 5.0E-63 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS01430 71f57e2666b402cbae0b42ef53d2aaf5 480 Pfam PF00367 phosphotransferase system, EIIB 8 41 4.2E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS01430 71f57e2666b402cbae0b42ef53d2aaf5 480 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 28 111 6.5E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS01430 71f57e2666b402cbae0b42ef53d2aaf5 480 Gene3D G3DSA:3.30.1360.60 4 81 1.2E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS01430 71f57e2666b402cbae0b42ef53d2aaf5 480 SUPERFAMILY SSF55604 6 81 1.15E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS03300 46c5bf0d0af0e2b71a2ee7911bebd4a2 333 Pfam PF00296 Luciferase-like monooxygenase 16 302 2.4E-35 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CWR44_RS03300 46c5bf0d0af0e2b71a2ee7911bebd4a2 333 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 331 1.3E-110 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CWR44_RS03300 46c5bf0d0af0e2b71a2ee7911bebd4a2 333 SUPERFAMILY SSF51679 2 330 1.77E-66 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CWR44_RS03300 46c5bf0d0af0e2b71a2ee7911bebd4a2 333 Gene3D G3DSA:3.20.20.30 1 332 1.2E-66 T 28-03-2018 CWR44_RS12605 08e22ca72591283eac38b968886b91a8 391 Gene3D G3DSA:1.10.443.10 175 371 7.7E-38 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS12605 08e22ca72591283eac38b968886b91a8 391 Pfam PF00589 Phage integrase family 176 368 7.2E-29 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS12605 08e22ca72591283eac38b968886b91a8 391 SUPERFAMILY SSF56349 64 375 1.68E-61 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR44_RS12605 08e22ca72591283eac38b968886b91a8 391 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 64 118 1.8E-9 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CWR44_RS12605 08e22ca72591283eac38b968886b91a8 391 Pfam PF14657 Arm DNA-binding domain 12 43 1.6E-6 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CWR44_RS12605 08e22ca72591283eac38b968886b91a8 391 Gene3D G3DSA:1.10.150.130 59 174 8.4E-20 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR44_RS02280 dd85fa1b4b249c4c2b26c4b84f20b3c5 502 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 5 499 1.6E-135 T 28-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 CWR44_RS02280 dd85fa1b4b249c4c2b26c4b84f20b3c5 502 SUPERFAMILY SSF51905 455 497 5.83E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS02280 dd85fa1b4b249c4c2b26c4b84f20b3c5 502 SUPERFAMILY SSF51905 3 321 5.83E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS02280 dd85fa1b4b249c4c2b26c4b84f20b3c5 502 Gene3D G3DSA:3.50.50.60 1 502 8.5E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS02280 dd85fa1b4b249c4c2b26c4b84f20b3c5 502 Pfam PF01593 Flavin containing amine oxidoreductase 12 495 8.0E-31 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CWR44_RS02280 dd85fa1b4b249c4c2b26c4b84f20b3c5 502 PRINTS PR00419 Adrenodoxin reductase family signature 26 39 1.1E-6 T 28-03-2018 CWR44_RS02280 dd85fa1b4b249c4c2b26c4b84f20b3c5 502 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 1.1E-6 T 28-03-2018 CWR44_RS07845 a9ea118fc55037ab1c2c019cfc6ad425 223 SUPERFAMILY SSF52317 1 217 4.45E-74 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS07845 a9ea118fc55037ab1c2c019cfc6ad425 223 PIRSF PIRSF001586 1 221 1.0E-79 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS07845 a9ea118fc55037ab1c2c019cfc6ad425 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 201 2.1E-45 T 28-03-2018 CWR44_RS07845 a9ea118fc55037ab1c2c019cfc6ad425 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 217 1.8E-95 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS07845 a9ea118fc55037ab1c2c019cfc6ad425 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 216 41.341 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS07845 a9ea118fc55037ab1c2c019cfc6ad425 223 SMART SM01211 1 218 7.4E-117 T 28-03-2018 CWR44_RS07845 a9ea118fc55037ab1c2c019cfc6ad425 223 Gene3D G3DSA:3.40.50.880 1 220 2.0E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS01980 dfb3f51cbf87e30ec3058e1d98cd1ce7 593 Pfam PF00999 Sodium/hydrogen exchanger family 11 394 1.0E-37 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CWR44_RS12555 81a30b544b8fc9f566ea2594532f5c5b 428 SUPERFAMILY SSF53383 22 420 1.96E-60 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS12555 81a30b544b8fc9f566ea2594532f5c5b 428 Gene3D G3DSA:3.90.1150.10 249 428 1.7E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS12555 81a30b544b8fc9f566ea2594532f5c5b 428 Pfam PF00155 Aminotransferase class I and II 75 420 1.8E-31 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR44_RS12555 81a30b544b8fc9f566ea2594532f5c5b 428 Gene3D G3DSA:3.40.640.10 69 248 1.7E-9 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS11580 a6134ae06a1c92f3314aadc301ebd3bd 198 Pfam PF14794 Domain of unknown function (DUF4479) 21 88 1.6E-20 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 CWR44_RS11580 a6134ae06a1c92f3314aadc301ebd3bd 198 Gene3D G3DSA:2.40.50.140 88 198 3.9E-38 T 28-03-2018 CWR44_RS11580 a6134ae06a1c92f3314aadc301ebd3bd 198 SUPERFAMILY SSF50249 89 197 4.65E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS11580 a6134ae06a1c92f3314aadc301ebd3bd 198 Gene3D G3DSA:3.30.1940.10 22 87 2.8E-21 T 28-03-2018 IPR027855 Domain of unknown function DUF4479 CWR44_RS11580 a6134ae06a1c92f3314aadc301ebd3bd 198 Pfam PF01588 Putative tRNA binding domain 93 194 2.9E-25 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CWR44_RS00990 d816668838a3bf49a134f525c832a8bb 249 Pfam PF05257 CHAP domain 148 224 1.6E-14 T 28-03-2018 IPR007921 CHAP domain CWR44_RS00990 d816668838a3bf49a134f525c832a8bb 249 SUPERFAMILY SSF54001 141 248 9.71E-14 T 28-03-2018 CWR44_RS11915 a460441ab653de3b8f66ba1d1ba5bd67 141 Pfam PF01230 HIT domain 12 107 1.8E-25 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CWR44_RS11915 a460441ab653de3b8f66ba1d1ba5bd67 141 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 28-03-2018 IPR019808 Histidine triad, conserved site CWR44_RS11915 a460441ab653de3b8f66ba1d1ba5bd67 141 Gene3D G3DSA:3.30.428.10 1 141 1.1E-39 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CWR44_RS11915 a460441ab653de3b8f66ba1d1ba5bd67 141 PRINTS PR00332 Histidine triad family signature 5 21 4.8E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CWR44_RS11915 a460441ab653de3b8f66ba1d1ba5bd67 141 PRINTS PR00332 Histidine triad family signature 26 44 4.8E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CWR44_RS11915 a460441ab653de3b8f66ba1d1ba5bd67 141 PRINTS PR00332 Histidine triad family signature 93 103 4.8E-16 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CWR44_RS11915 a460441ab653de3b8f66ba1d1ba5bd67 141 SUPERFAMILY SSF54197 3 140 7.27E-43 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CWR44_RS07390 b84af45d3df0a5d897d30369fa9383e5 174 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 125 144 8.9E-10 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS07390 b84af45d3df0a5d897d30369fa9383e5 174 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 8.9E-10 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS07390 b84af45d3df0a5d897d30369fa9383e5 174 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 73 85 8.9E-10 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS07390 b84af45d3df0a5d897d30369fa9383e5 174 Gene3D G3DSA:2.10.109.10 20 174 4.0E-30 T 28-03-2018 CWR44_RS07390 b84af45d3df0a5d897d30369fa9383e5 174 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 7 165 2.8E-39 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CWR44_RS07390 b84af45d3df0a5d897d30369fa9383e5 174 SUPERFAMILY SSF51306 23 171 7.12E-35 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR44_RS07390 b84af45d3df0a5d897d30369fa9383e5 174 Pfam PF00717 Peptidase S24-like 31 100 1.5E-9 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR44_RS01260 2413121e0175c0f49c05af4a8fa09355 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 53 3.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS01260 2413121e0175c0f49c05af4a8fa09355 183 SUPERFAMILY SSF46689 4 65 5.2E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS01260 2413121e0175c0f49c05af4a8fa09355 183 Gene3D G3DSA:1.10.10.60 44 175 4.4E-4 T 28-03-2018 CWR44_RS01260 2413121e0175c0f49c05af4a8fa09355 183 Gene3D G3DSA:1.10.10.60 3 43 1.3E-8 T 28-03-2018 CWR44_RS01260 2413121e0175c0f49c05af4a8fa09355 183 Pfam PF14278 Transcriptional regulator C-terminal region 87 160 5.1E-8 T 28-03-2018 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 Gene3D G3DSA:3.30.65.10 587 635 1.0E-7 T 28-03-2018 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 Pfam PF01131 DNA topoisomerase 152 569 1.2E-107 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 Gene3D G3DSA:2.20.25.10 636 673 0.013 T 28-03-2018 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 Gene3D G3DSA:3.40.50.140 2 153 1.9E-40 T 28-03-2018 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 SUPERFAMILY SSF56712 2 585 1.57E-163 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 Gene3D G3DSA:2.70.20.10 344 456 7.8E-22 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 Pfam PF01751 Toprim domain 4 133 6.7E-17 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 382 398 3.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 498 512 3.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 300 309 3.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 3.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 3.3E-24 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 Gene3D G3DSA:1.10.460.10 158 337 2.4E-36 T 28-03-2018 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 Gene3D G3DSA:1.10.460.10 457 586 2.7E-21 T 28-03-2018 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 SMART SM00493 2 125 6.8E-15 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 294 309 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 SMART SM00436 125 215 1.2E-34 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 696 1.0E-197 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 SMART SM00437 257 535 3.0E-69 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CWR44_RS00815 7216dc531efad1cfeddcb62492c3c198 711 Hamap MF_00953 DNA topoisomerase 3 [topB]. 2 624 60.905 T 28-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CWR44_RS01085 dcb1dbc07f4d5ae51bf4e99ce9bb151e 295 Gene3D G3DSA:3.40.50.10490 8 237 8.2E-52 T 28-03-2018 CWR44_RS01085 dcb1dbc07f4d5ae51bf4e99ce9bb151e 295 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 293 40.143 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CWR44_RS01085 dcb1dbc07f4d5ae51bf4e99ce9bb151e 295 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 183 200 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CWR44_RS01085 dcb1dbc07f4d5ae51bf4e99ce9bb151e 295 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 4 293 2.6E-113 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CWR44_RS01085 dcb1dbc07f4d5ae51bf4e99ce9bb151e 295 SUPERFAMILY SSF53697 3 245 7.79E-71 T 28-03-2018 CWR44_RS01085 dcb1dbc07f4d5ae51bf4e99ce9bb151e 295 Pfam PF01380 SIS domain 126 206 1.0E-9 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR44_RS01085 dcb1dbc07f4d5ae51bf4e99ce9bb151e 295 Gene3D G3DSA:1.10.8.10 266 294 0.0012 T 28-03-2018 CWR44_RS01085 dcb1dbc07f4d5ae51bf4e99ce9bb151e 295 Gene3D G3DSA:1.10.8.10 238 265 3.0E-5 T 28-03-2018 CWR44_RS04640 eb0209c01cc1328fc7fe77a850be7d57 85 SUPERFAMILY SSF47413 4 71 1.55E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS04640 eb0209c01cc1328fc7fe77a850be7d57 85 Gene3D G3DSA:1.10.260.40 2 84 1.1E-7 T 28-03-2018 CWR44_RS08475 a4055af0b9c7c004db35759b50ba207e 67 Pfam PF05154 TM2 domain 2 51 5.4E-17 T 28-03-2018 IPR007829 TM2 domain CWR44_RS05585 19c510c32466d77ba0fd7a1af6fe405c 196 Gene3D G3DSA:1.10.10.10 117 195 2.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS05585 19c510c32466d77ba0fd7a1af6fe405c 196 SUPERFAMILY SSF46894 127 188 6.8E-7 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS05585 19c510c32466d77ba0fd7a1af6fe405c 196 SUPERFAMILY SSF88946 25 109 2.51E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS05585 19c510c32466d77ba0fd7a1af6fe405c 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 190 2.9E-17 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS05585 19c510c32466d77ba0fd7a1af6fe405c 196 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 188 9.2E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CWR44_RS05585 19c510c32466d77ba0fd7a1af6fe405c 196 Pfam PF04542 Sigma-70 region 2 34 98 1.1E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CWR44_RS05585 19c510c32466d77ba0fd7a1af6fe405c 196 Gene3D G3DSA:1.10.1740.10 15 98 2.9E-10 T 28-03-2018 CWR44_RS02915 0eb88c639f586c367b84970a73f26d4b 889 Gene3D G3DSA:1.20.1640.10 79 344 9.4E-36 T 28-03-2018 CWR44_RS02915 0eb88c639f586c367b84970a73f26d4b 889 SUPERFAMILY SSF82866 454 692 1.57E-30 T 28-03-2018 CWR44_RS02915 0eb88c639f586c367b84970a73f26d4b 889 SUPERFAMILY SSF82866 125 332 2.09E-30 T 28-03-2018 CWR44_RS02915 0eb88c639f586c367b84970a73f26d4b 889 Gene3D G3DSA:1.20.1640.10 469 690 2.3E-32 T 28-03-2018 CWR44_RS02915 0eb88c639f586c367b84970a73f26d4b 889 Pfam PF03176 MMPL family 46 359 1.7E-62 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CWR44_RS02915 0eb88c639f586c367b84970a73f26d4b 889 Pfam PF03176 MMPL family 389 695 5.4E-40 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 350 1.7E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 394 427 9.2E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 260 282 2.8E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 Gene3D G3DSA:3.90.550.10 2 239 7.4E-60 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 402 430 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 450 3.2E-176 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 Pfam PF00483 Nucleotidyl transferase 5 211 2.7E-23 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 451 40.793 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 Gene3D G3DSA:2.160.10.10 345 450 3.7E-18 T 28-03-2018 CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 SUPERFAMILY SSF53448 4 306 2.48E-61 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 Gene3D G3DSA:2.160.10.10 240 344 7.6E-28 T 28-03-2018 CWR44_RS05325 71db27acaeef01779d448e2fae7b961a 451 SUPERFAMILY SSF51161 254 445 5.21E-45 T 28-03-2018 IPR011004 Trimeric LpxA-like CWR44_RS09020 84be08d3e0c52e6450f26c9dd19d5887 224 Pfam PF16784 Putative HNHc nuclease 22 220 4.7E-71 T 28-03-2018 IPR031879 Fanconi anemia group M protein, MHF binding domain Reactome: R-HSA-6783310 CWR44_RS09020 84be08d3e0c52e6450f26c9dd19d5887 224 Gene3D G3DSA:3.30.50.20 146 217 5.6E-4 T 28-03-2018 CWR44_RS01995 4f760a03b438f96ff9fec43993a0b59b 301 SUPERFAMILY SSF54593 3 283 4.1E-39 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS01995 4f760a03b438f96ff9fec43993a0b59b 301 Gene3D G3DSA:3.10.180.10 2 134 2.8E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS01995 4f760a03b438f96ff9fec43993a0b59b 301 Gene3D G3DSA:3.10.180.10 135 301 1.3E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS01995 4f760a03b438f96ff9fec43993a0b59b 301 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 113 2.5E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWR44_RS01995 4f760a03b438f96ff9fec43993a0b59b 301 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 256 6.7E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWR44_RS03280 74ed9b76ded7df5fe063b6d159a784e1 472 PIRSF PIRSF002457 1 472 6.8E-148 T 28-03-2018 IPR030676 Citrate carrier CitT-related CWR44_RS03280 74ed9b76ded7df5fe063b6d159a784e1 472 Pfam PF00939 Sodium:sulfate symporter transmembrane region 8 470 7.2E-151 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CWR44_RS03280 74ed9b76ded7df5fe063b6d159a784e1 472 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 28 465 8.4E-131 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CWR44_RS12270 395dc4c49891bcc197c8a9f4fbab7b7c 177 Pfam PF03061 Thioesterase superfamily 31 102 8.8E-16 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CWR44_RS12270 395dc4c49891bcc197c8a9f4fbab7b7c 177 Gene3D G3DSA:3.10.129.10 8 165 4.3E-44 T 28-03-2018 CWR44_RS12270 395dc4c49891bcc197c8a9f4fbab7b7c 177 SUPERFAMILY SSF54637 10 159 1.01E-43 T 28-03-2018 IPR029069 HotDog domain CWR44_RS06655 bbcca489a91665c3eae146b71acb98a6 177 Gene3D G3DSA:1.10.40.40 18 58 5.5E-16 T 28-03-2018 CWR44_RS06655 bbcca489a91665c3eae146b71acb98a6 177 SUPERFAMILY SSF56784 4 174 1.07E-33 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS06655 bbcca489a91665c3eae146b71acb98a6 177 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 6 173 6.4E-34 T 28-03-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 CWR44_RS06655 bbcca489a91665c3eae146b71acb98a6 177 Gene3D G3DSA:3.40.50.1000 59 176 9.3E-30 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS03015 93c39bd91330b842c92384e106d9567b 3887 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 16 33 2.8E-7 T 28-03-2018 IPR022263 KxYKxGKxW signal peptide CWR44_RS03015 93c39bd91330b842c92384e106d9567b 3887 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 3842 3877 3.2E-5 T 28-03-2018 CWR44_RS03015 93c39bd91330b842c92384e106d9567b 3887 Pfam PF00746 LPXTG cell wall anchor motif 3838 3878 9.4E-8 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWR44_RS10075 9b7b4835acab6d4eb0f54792f02b4457 219 SUPERFAMILY SSF46894 119 218 4.54E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS10075 9b7b4835acab6d4eb0f54792f02b4457 219 SMART SM00862 143 218 4.8E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS10075 9b7b4835acab6d4eb0f54792f02b4457 219 Gene3D G3DSA:3.40.50.2300 1 116 4.6E-34 T 28-03-2018 CWR44_RS10075 9b7b4835acab6d4eb0f54792f02b4457 219 SMART SM00448 2 112 1.6E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS10075 9b7b4835acab6d4eb0f54792f02b4457 219 SUPERFAMILY SSF52172 3 118 1.99E-39 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS10075 9b7b4835acab6d4eb0f54792f02b4457 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 217 1.6E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS10075 9b7b4835acab6d4eb0f54792f02b4457 219 Gene3D G3DSA:1.10.10.10 117 219 1.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10075 9b7b4835acab6d4eb0f54792f02b4457 219 Pfam PF00072 Response regulator receiver domain 4 113 4.2E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS08605 6be6435c5583cc9847ec5deca8d7b7d5 167 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 165 24.795 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CWR44_RS08605 6be6435c5583cc9847ec5deca8d7b7d5 167 Pfam PF05239 PRC-barrel domain 94 166 2.2E-12 T 28-03-2018 IPR027275 PRC-barrel domain CWR44_RS08605 6be6435c5583cc9847ec5deca8d7b7d5 167 Pfam PF01782 RimM N-terminal domain 4 86 3.1E-25 T 28-03-2018 IPR002676 RimM protein GO:0006364 CWR44_RS08605 6be6435c5583cc9847ec5deca8d7b7d5 167 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 165 7.2E-49 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CWR44_RS08605 6be6435c5583cc9847ec5deca8d7b7d5 167 SUPERFAMILY SSF50346 97 165 9.42E-21 T 28-03-2018 IPR011033 PRC-barrel-like CWR44_RS08605 6be6435c5583cc9847ec5deca8d7b7d5 167 Gene3D G3DSA:2.40.30.60 2 88 7.8E-24 T 28-03-2018 IPR002676 RimM protein GO:0006364 CWR44_RS08605 6be6435c5583cc9847ec5deca8d7b7d5 167 Gene3D G3DSA:2.30.30.240 93 160 2.5E-22 T 28-03-2018 CWR44_RS08605 6be6435c5583cc9847ec5deca8d7b7d5 167 SUPERFAMILY SSF50447 3 86 1.31E-21 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 40 55 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 304 327 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 Gene3D G3DSA:1.10.3860.10 1 416 3.1E-130 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 PRINTS PR00173 Glutamate-aspartate symporter signature 301 327 1.3E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 PRINTS PR00173 Glutamate-aspartate symporter signature 226 245 1.3E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 1.3E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 PRINTS PR00173 Glutamate-aspartate symporter signature 201 220 1.3E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 PRINTS PR00173 Glutamate-aspartate symporter signature 154 176 1.3E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 PRINTS PR00173 Glutamate-aspartate symporter signature 363 383 1.3E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 1.3E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 PRINTS PR00173 Glutamate-aspartate symporter signature 336 355 1.3E-42 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 SUPERFAMILY SSF118215 10 410 1.07E-123 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS01455 1aaaf69dc14c3663bda4325fc3043272 425 Pfam PF00375 Sodium:dicarboxylate symporter family 11 409 8.3E-124 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS03635 bf4ab73a0bf2a9da3055537d8042ac9a 431 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 17 421 3.9E-122 T 28-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CWR44_RS03635 bf4ab73a0bf2a9da3055537d8042ac9a 431 Pfam PF02378 Phosphotransferase system, EIIC 29 347 7.5E-56 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS03635 bf4ab73a0bf2a9da3055537d8042ac9a 431 PIRSF PIRSF006351 1 430 1.4E-144 T 28-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CWR44_RS10635 a05a8801520856cf09af91f5ac9b1f71 106 Gene3D G3DSA:3.30.700.10 14 105 1.1E-11 T 28-03-2018 CWR44_RS10635 a05a8801520856cf09af91f5ac9b1f71 106 PRINTS PR00813 Bacterial general secretion pathway protein G signature 13 38 3.0E-8 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CWR44_RS10635 a05a8801520856cf09af91f5ac9b1f71 106 PRINTS PR00813 Bacterial general secretion pathway protein G signature 49 67 3.0E-8 T 28-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CWR44_RS10635 a05a8801520856cf09af91f5ac9b1f71 106 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 33 6.4E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR44_RS10635 a05a8801520856cf09af91f5ac9b1f71 106 PIRSF PIRSF029928 1 106 8.4E-37 T 28-03-2018 IPR016940 ComG operon protein C GO:0030420 CWR44_RS10635 a05a8801520856cf09af91f5ac9b1f71 106 SUPERFAMILY SSF54523 14 80 9.42E-15 T 28-03-2018 CWR44_RS10635 a05a8801520856cf09af91f5ac9b1f71 106 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 33 7.3E-5 T 28-03-2018 IPR012902 Prokaryotic N-terminal methylation site CWR44_RS07175 8a6a77537fe0fc3da018cc9eeab24bd7 282 Pfam PF01904 Protein of unknown function DUF72 20 264 7.2E-59 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CWR44_RS07175 8a6a77537fe0fc3da018cc9eeab24bd7 282 SUPERFAMILY SSF117396 1 269 3.53E-82 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CWR44_RS07175 8a6a77537fe0fc3da018cc9eeab24bd7 282 Gene3D G3DSA:3.20.20.410 1 282 4.6E-80 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 PRINTS PR01466 Bacterial arginine deiminase signature 390 408 4.3E-54 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 PRINTS PR01466 Bacterial arginine deiminase signature 4 24 4.3E-54 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 PRINTS PR01466 Bacterial arginine deiminase signature 347 364 4.3E-54 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 PRINTS PR01466 Bacterial arginine deiminase signature 152 170 4.3E-54 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 PRINTS PR01466 Bacterial arginine deiminase signature 180 195 4.3E-54 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 PRINTS PR01466 Bacterial arginine deiminase signature 367 381 4.3E-54 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 Gene3D G3DSA:3.75.10.10 5 409 1.0E-101 T 28-03-2018 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 TIGRFAM TIGR01078 arcA: arginine deiminase 6 411 2.8E-166 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 Hamap MF_00242 Arginine deiminase [arcA]. 3 411 47.458 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 Pfam PF02274 Amidinotransferase 20 408 1.0E-116 T 28-03-2018 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 PIRSF PIRSF006356 1 411 1.0E-171 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CWR44_RS02850 e27d12c89d0e89da659ec220c7ba008b 411 SUPERFAMILY SSF55909 4 411 6.87E-136 T 28-03-2018 CWR44_RS11125 07510057766d8b643864bec97a3ba532 94 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 26.947 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11125 07510057766d8b643864bec97a3ba532 94 Gene3D G3DSA:2.40.50.100 28 92 5.8E-29 T 28-03-2018 CWR44_RS11125 07510057766d8b643864bec97a3ba532 94 PRINTS PR00063 Ribosomal protein L27 signature 12 36 5.4E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11125 07510057766d8b643864bec97a3ba532 94 PRINTS PR00063 Ribosomal protein L27 signature 62 86 5.4E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11125 07510057766d8b643864bec97a3ba532 94 PRINTS PR00063 Ribosomal protein L27 signature 37 61 5.4E-38 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11125 07510057766d8b643864bec97a3ba532 94 SUPERFAMILY SSF110324 10 91 3.38E-32 T 28-03-2018 CWR44_RS11125 07510057766d8b643864bec97a3ba532 94 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS11125 07510057766d8b643864bec97a3ba532 94 Pfam PF01016 Ribosomal L27 protein 10 89 2.8E-34 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11125 07510057766d8b643864bec97a3ba532 94 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 3.0E-39 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11125 07510057766d8b643864bec97a3ba532 94 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 8.0E-18 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS13165 fe5debb9dba420d93dffa9adc9418794 91 Pfam PF02583 Metal-sensitive transcriptional repressor 9 87 1.6E-28 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CWR44_RS09085 436918633eb39c01b0d4d78a9a8cca93 104 Gene3D G3DSA:1.10.287.1080 1 84 5.5E-13 T 28-03-2018 CWR44_RS09085 436918633eb39c01b0d4d78a9a8cca93 104 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 33 89 6.2E-7 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CWR44_RS09085 436918633eb39c01b0d4d78a9a8cca93 104 SUPERFAMILY SSF101386 2 90 8.78E-14 T 28-03-2018 CWR44_RS07170 44875b0da5ddad6e9fc38c9a924a419b 357 Gene3D G3DSA:3.20.20.70 4 357 2.9E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS07170 44875b0da5ddad6e9fc38c9a924a419b 357 SUPERFAMILY SSF51412 6 354 9.62E-63 T 28-03-2018 CWR44_RS07170 44875b0da5ddad6e9fc38c9a924a419b 357 Pfam PF03060 Nitronate monooxygenase 6 347 4.2E-95 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CWR44_RS10160 6b6cb4f9a6b1601a7f61765dd8190dc1 133 Pfam PF13456 Reverse transcriptase-like 6 124 1.4E-18 T 28-03-2018 CWR44_RS10160 6b6cb4f9a6b1601a7f61765dd8190dc1 133 Gene3D G3DSA:3.30.420.10 1 124 9.4E-24 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS10160 6b6cb4f9a6b1601a7f61765dd8190dc1 133 SUPERFAMILY SSF53098 2 122 2.91E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS04235 d2de4d5fa27c7a7816e1cdea4575a056 559 Pfam PF00239 Resolvase, N terminal domain 6 154 1.6E-30 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS04235 d2de4d5fa27c7a7816e1cdea4575a056 559 SUPERFAMILY SSF53041 4 154 4.97E-29 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS04235 d2de4d5fa27c7a7816e1cdea4575a056 559 SMART SM00857 5 155 8.8E-45 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CWR44_RS04235 d2de4d5fa27c7a7816e1cdea4575a056 559 Pfam PF07508 Recombinase 180 285 2.8E-23 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CWR44_RS04235 d2de4d5fa27c7a7816e1cdea4575a056 559 Gene3D G3DSA:1.20.58.60 263 455 7.0E-5 T 28-03-2018 CWR44_RS04235 d2de4d5fa27c7a7816e1cdea4575a056 559 Pfam PF13408 Recombinase zinc beta ribbon domain 299 361 1.1E-9 T 28-03-2018 IPR025827 Recombinase zinc beta ribbon domain CWR44_RS04235 d2de4d5fa27c7a7816e1cdea4575a056 559 Gene3D G3DSA:3.40.50.1390 1 162 7.0E-35 T 28-03-2018 CWR44_RS06715 58968fd22fc82ffe8c1aef267bc5e4f8 345 Gene3D G3DSA:3.40.50.1980 184 344 1.4E-33 T 28-03-2018 CWR44_RS06715 58968fd22fc82ffe8c1aef267bc5e4f8 345 SUPERFAMILY SSF53807 64 335 2.43E-59 T 28-03-2018 CWR44_RS06715 58968fd22fc82ffe8c1aef267bc5e4f8 345 Gene3D G3DSA:3.40.50.1980 27 183 1.3E-26 T 28-03-2018 CWR44_RS06715 58968fd22fc82ffe8c1aef267bc5e4f8 345 Pfam PF01497 Periplasmic binding protein 76 320 1.5E-31 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CWR44_RS02330 ecb8a021bef6a7e018b91a58a2d8496e 314 SUPERFAMILY SSF51679 19 305 5.05E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CWR44_RS02330 ecb8a021bef6a7e018b91a58a2d8496e 314 Gene3D G3DSA:3.20.20.30 1 239 1.4E-42 T 28-03-2018 CWR44_RS02330 ecb8a021bef6a7e018b91a58a2d8496e 314 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 9 309 3.4E-118 T 28-03-2018 IPR020020 Luciferase-type oxidoreductase CWR44_RS02330 ecb8a021bef6a7e018b91a58a2d8496e 314 Pfam PF00296 Luciferase-like monooxygenase 28 234 5.1E-33 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CWR44_RS06510 f7e24b2a383e69afd5b9b9e24a066590 390 Pfam PF07690 Major Facilitator Superfamily 9 335 1.9E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS06510 f7e24b2a383e69afd5b9b9e24a066590 390 SUPERFAMILY SSF103473 3 377 2.49E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS06510 f7e24b2a383e69afd5b9b9e24a066590 390 Gene3D G3DSA:1.20.1250.20 192 390 3.8E-21 T 28-03-2018 CWR44_RS06510 f7e24b2a383e69afd5b9b9e24a066590 390 Gene3D G3DSA:1.20.1250.20 1 191 1.3E-38 T 28-03-2018 CWR44_RS06510 f7e24b2a383e69afd5b9b9e24a066590 390 TIGRFAM TIGR00880 2_A_01_02: multidrug resistance protein 41 178 2.6E-39 T 28-03-2018 IPR004734 Multidrug resistance protein GO:0015238|GO:0015893|GO:0016021 Reactome: R-HSA-442660 CWR44_RS06510 f7e24b2a383e69afd5b9b9e24a066590 390 PRINTS PR01035 Tetracycline resistance protein signature 240 260 4.1E-25 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR44_RS06510 f7e24b2a383e69afd5b9b9e24a066590 390 PRINTS PR01035 Tetracycline resistance protein signature 14 30 4.1E-25 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR44_RS06510 f7e24b2a383e69afd5b9b9e24a066590 390 PRINTS PR01035 Tetracycline resistance protein signature 157 177 4.1E-25 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR44_RS06510 f7e24b2a383e69afd5b9b9e24a066590 390 PRINTS PR01035 Tetracycline resistance protein signature 328 351 4.1E-25 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR44_RS06510 f7e24b2a383e69afd5b9b9e24a066590 390 PRINTS PR01035 Tetracycline resistance protein signature 129 151 4.1E-25 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 Gene3D G3DSA:3.40.50.1980 27 198 1.1E-49 T 28-03-2018 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 SUPERFAMILY SSF53807 37 318 8.83E-71 T 28-03-2018 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 Pfam PF01297 Zinc-uptake complex component A periplasmic 41 317 6.1E-61 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 PRINTS PR00690 Adhesin family signature 204 225 7.1E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 PRINTS PR00690 Adhesin family signature 82 99 7.1E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 PRINTS PR00690 Adhesin family signature 38 56 7.1E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 PRINTS PR00690 Adhesin family signature 256 274 7.1E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 PRINTS PR00690 Adhesin family signature 69 82 7.1E-9 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 Gene3D G3DSA:3.40.50.1980 199 319 3.8E-25 T 28-03-2018 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 PRINTS PR00691 Adhesin B signature 148 167 1.3E-10 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 PRINTS PR00691 Adhesin B signature 297 315 1.3E-10 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 PRINTS PR00691 Adhesin B signature 38 59 1.3E-10 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 PRINTS PR00691 Adhesin B signature 63 81 1.3E-10 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS02015 29e127d58bbff251f18a7c844c98e3d4 320 PRINTS PR00691 Adhesin B signature 252 269 1.3E-10 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 SUPERFAMILY SSF50249 9 102 2.08E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 5.8E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 5.8E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 5.8E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 5.8E-16 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 2 429 1.6E-165 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 Gene3D G3DSA:3.30.930.10 101 430 2.4E-91 T 28-03-2018 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 Gene3D G3DSA:2.40.50.140 1 100 1.2E-20 T 28-03-2018 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 Pfam PF01336 OB-fold nucleic acid binding domain 16 95 1.4E-14 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 430 41.797 T 28-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 SUPERFAMILY SSF55681 110 424 3.73E-96 T 28-03-2018 CWR44_RS10240 6f48812b768cc569fddcaf648949730d 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 2.6E-83 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CWR44_RS04495 a2dc01ec28bbcc9116ef5ca2ab2e7156 190 Gene3D G3DSA:1.10.260.40 1 163 3.3E-23 T 28-03-2018 CWR44_RS04495 a2dc01ec28bbcc9116ef5ca2ab2e7156 190 Pfam PF01381 Helix-turn-helix 7 61 3.0E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS04495 a2dc01ec28bbcc9116ef5ca2ab2e7156 190 SMART SM00530 6 61 4.0E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS04495 a2dc01ec28bbcc9116ef5ca2ab2e7156 190 SUPERFAMILY SSF47413 1 65 5.63E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS08860 72cf63bb2a38207b2595d11791379cb6 288 SUPERFAMILY SSF52518 12 251 4.05E-78 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS08860 72cf63bb2a38207b2595d11791379cb6 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 6.1E-33 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR44_RS08860 72cf63bb2a38207b2595d11791379cb6 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 264 1.3E-21 T 28-03-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal CWR44_RS08860 72cf63bb2a38207b2595d11791379cb6 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 270 9.0E-98 T 28-03-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate CWR44_RS08860 72cf63bb2a38207b2595d11791379cb6 288 Gene3D G3DSA:3.40.50.970 73 287 8.6E-46 T 28-03-2018 CWR44_RS08860 72cf63bb2a38207b2595d11791379cb6 288 Gene3D G3DSA:3.40.50.970 6 72 4.5E-15 T 28-03-2018 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 559 581 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 Pfam PF02867 Ribonucleotide reductase, barrel domain 169 685 6.1E-136 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 SUPERFAMILY SSF48168 10 167 1.44E-40 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 10 701 0.0 T 28-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 93 164 8.2E-15 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 PRINTS PR01183 Ribonucleotide reductase large chain signature 377 388 8.1E-29 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 PRINTS PR01183 Ribonucleotide reductase large chain signature 460 482 8.1E-29 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 PRINTS PR01183 Ribonucleotide reductase large chain signature 244 263 8.1E-29 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 PRINTS PR01183 Ribonucleotide reductase large chain signature 570 597 8.1E-29 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 PRINTS PR01183 Ribonucleotide reductase large chain signature 488 511 8.1E-29 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 95 688 1.2E-164 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 Pfam PF08343 Ribonucleotide reductase N-terminal 11 90 3.9E-20 T 28-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 SUPERFAMILY SSF51998 168 688 1.19E-171 T 28-03-2018 CWR44_RS06690 46ca58a6fbcf4ec240e97c5c62703826 701 Gene3D G3DSA:3.20.70.20 74 692 1.2E-150 T 28-03-2018 CWR44_RS12310 34aa0bf27d344f49e17fda69d8ae2be2 233 PIRSF PIRSF031509 5 233 7.7E-55 T 28-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 CWR44_RS12310 34aa0bf27d344f49e17fda69d8ae2be2 233 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 119 230 8.5E-30 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 PIRSF PIRSF015592 1 210 6.8E-78 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 199 36.719 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 208 1.8E-70 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 Gene3D G3DSA:3.40.630.20 1 212 1.3E-61 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 2.0E-45 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 2.0E-45 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 2.0E-45 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 2.0E-45 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 2.0E-45 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 SUPERFAMILY SSF53182 1 200 2.09E-66 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 28-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 Pfam PF01470 Pyroglutamyl peptidase 1 201 1.4E-87 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CWR44_RS03170 15222f83e5a8c358396349eb3c5788d1 212 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 28-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site CWR44_RS03215 97caae8b582890546d11468cfe21fdb9 272 Pfam PF02517 CAAX protease self-immunity 117 212 3.3E-15 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR44_RS08705 318b672b6c2ab51c98ce39afabffe6ca 184 TIGRFAM TIGR00496 frr: ribosome recycling factor 9 184 1.2E-71 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CWR44_RS08705 318b672b6c2ab51c98ce39afabffe6ca 184 Hamap MF_00040 Ribosome-recycling factor [frr]. 2 184 27.427 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CWR44_RS08705 318b672b6c2ab51c98ce39afabffe6ca 184 Gene3D G3DSA:1.10.132.20 1 73 6.0E-10 T 28-03-2018 CWR44_RS08705 318b672b6c2ab51c98ce39afabffe6ca 184 Gene3D G3DSA:1.10.132.20 74 183 4.4E-38 T 28-03-2018 CWR44_RS08705 318b672b6c2ab51c98ce39afabffe6ca 184 SUPERFAMILY SSF55194 2 182 7.06E-69 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CWR44_RS08705 318b672b6c2ab51c98ce39afabffe6ca 184 Pfam PF01765 Ribosome recycling factor 19 182 4.5E-63 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CWR44_RS02100 4e7e2b29a1407e919cd2f34094af782a 150 PRINTS PR01759 Capsule biosynthesis protein CapC signature 66 80 7.0E-37 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CWR44_RS02100 4e7e2b29a1407e919cd2f34094af782a 150 PRINTS PR01759 Capsule biosynthesis protein CapC signature 20 37 7.0E-37 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CWR44_RS02100 4e7e2b29a1407e919cd2f34094af782a 150 PRINTS PR01759 Capsule biosynthesis protein CapC signature 88 101 7.0E-37 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CWR44_RS02100 4e7e2b29a1407e919cd2f34094af782a 150 PRINTS PR01759 Capsule biosynthesis protein CapC signature 2 17 7.0E-37 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CWR44_RS02100 4e7e2b29a1407e919cd2f34094af782a 150 PRINTS PR01759 Capsule biosynthesis protein CapC signature 118 132 7.0E-37 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CWR44_RS02100 4e7e2b29a1407e919cd2f34094af782a 150 TIGRFAM TIGR04011 poly_gGlu_PgsC: poly-gamma-glutamate biosynthesis protein PgsC 11 140 6.3E-44 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CWR44_RS02100 4e7e2b29a1407e919cd2f34094af782a 150 Pfam PF14102 Capsule biosynthesis CapC 12 129 4.7E-40 T 28-03-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 CWR44_RS04475 11ccf9dacdf384ce483df6065fb19f41 279 Pfam PF02195 ParB-like nuclease domain 31 120 1.6E-24 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWR44_RS04475 11ccf9dacdf384ce483df6065fb19f41 279 Gene3D G3DSA:3.90.1530.10 19 120 3.4E-34 T 28-03-2018 CWR44_RS04475 11ccf9dacdf384ce483df6065fb19f41 279 SUPERFAMILY SSF110849 30 122 9.16E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWR44_RS04475 11ccf9dacdf384ce483df6065fb19f41 279 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 29 204 9.8E-56 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CWR44_RS04475 11ccf9dacdf384ce483df6065fb19f41 279 SMART SM00470 30 120 6.5E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWR44_RS04475 11ccf9dacdf384ce483df6065fb19f41 279 SUPERFAMILY SSF109709 113 220 5.49E-33 T 28-03-2018 CWR44_RS04475 11ccf9dacdf384ce483df6065fb19f41 279 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 29 278 1.6E-96 T 28-03-2018 IPR023705 Nucleoid occlusion protein CWR44_RS04475 11ccf9dacdf384ce483df6065fb19f41 279 Gene3D G3DSA:1.10.10.730 121 168 2.8E-21 T 28-03-2018 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 3.3E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 56 77 3.3E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 3.3E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 3.3E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 3.3E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 56 3.3E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 3.3E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 3.3E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 3.3E-61 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 Pfam PF13416 Bacterial extracellular solute-binding protein 49 320 1.0E-35 T 28-03-2018 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 Gene3D G3DSA:3.40.190.10 31 153 2.6E-17 T 28-03-2018 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 Gene3D G3DSA:3.40.190.10 154 307 5.2E-35 T 28-03-2018 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 PIRSF PIRSF019574 1 356 9.8E-134 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CWR44_RS08030 58768c85078b8e225b8049cb203e485b 357 SUPERFAMILY SSF53850 34 353 4.94E-90 T 28-03-2018 CWR44_RS11180 0d6a6b3de2b0cb5949ba6e450ea49d04 420 SUPERFAMILY SSF53244 295 415 1.21E-24 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR44_RS11180 0d6a6b3de2b0cb5949ba6e450ea49d04 420 SUPERFAMILY SSF53623 1 293 1.27E-81 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS11180 0d6a6b3de2b0cb5949ba6e450ea49d04 420 Gene3D G3DSA:3.40.1190.10 1 294 1.5E-70 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS11180 0d6a6b3de2b0cb5949ba6e450ea49d04 420 Pfam PF08245 Mur ligase middle domain 44 267 3.2E-11 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS11180 0d6a6b3de2b0cb5949ba6e450ea49d04 420 Pfam PF02875 Mur ligase family, glutamate ligase domain 293 356 1.9E-7 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CWR44_RS11180 0d6a6b3de2b0cb5949ba6e450ea49d04 420 PIRSF PIRSF001563 1 419 1.9E-125 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CWR44_RS11180 0d6a6b3de2b0cb5949ba6e450ea49d04 420 TIGRFAM TIGR01499 folC: bifunctional protein FolC 23 416 9.4E-111 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CWR44_RS11180 0d6a6b3de2b0cb5949ba6e450ea49d04 420 Gene3D G3DSA:3.90.190.20 295 419 2.2E-18 T 28-03-2018 CWR44_RS12640 81b1a2b77ed4822f8e1041bf1e918c6a 188 Pfam PF04647 Accessory gene regulator B 9 177 7.7E-32 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CWR44_RS12640 81b1a2b77ed4822f8e1041bf1e918c6a 188 Hamap MF_00784 Accessory gene regulator protein B [agrB]. 3 187 20.511 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CWR44_RS12640 81b1a2b77ed4822f8e1041bf1e918c6a 188 SMART SM00793 6 187 5.9E-98 T 28-03-2018 IPR006741 Accessory gene regulator B GO:0008233|GO:0009372|GO:0009405|GO:0016021 CWR44_RS00630 f04fbd0f3bcc1ccdda30be959aaf6c1e 132 Pfam PF00380 Ribosomal protein S9/S16 12 132 2.9E-46 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00630 f04fbd0f3bcc1ccdda30be959aaf6c1e 132 ProSitePatterns PS00360 Ribosomal protein S9 signature. 71 89 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CWR44_RS00630 f04fbd0f3bcc1ccdda30be959aaf6c1e 132 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 3 132 33.996 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CWR44_RS00630 f04fbd0f3bcc1ccdda30be959aaf6c1e 132 SUPERFAMILY SSF54211 8 132 3.0E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS00630 f04fbd0f3bcc1ccdda30be959aaf6c1e 132 Gene3D G3DSA:3.30.230.10 5 132 2.1E-51 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS12475 943456bf7d74e2be10799bb748da245d 309 Pfam PF01368 DHH family 3 146 1.8E-28 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR44_RS12475 943456bf7d74e2be10799bb748da245d 309 Gene3D G3DSA:3.90.1640.10 1 188 1.0E-63 T 28-03-2018 CWR44_RS12475 943456bf7d74e2be10799bb748da245d 309 Pfam PF02833 DHHA2 domain 183 306 9.9E-20 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR44_RS12475 943456bf7d74e2be10799bb748da245d 309 SUPERFAMILY SSF64182 3 306 3.66E-80 T 28-03-2018 CWR44_RS12475 943456bf7d74e2be10799bb748da245d 309 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 45.842 T 28-03-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR44_RS12475 943456bf7d74e2be10799bb748da245d 309 SMART SM01131 181 307 4.7E-53 T 28-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR44_RS03865 b4921873da6c7a58189e05ca00641dcf 399 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 210 5.8E-60 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CWR44_RS03865 b4921873da6c7a58189e05ca00641dcf 399 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 260 375 5.2E-25 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CWR44_RS03865 b4921873da6c7a58189e05ca00641dcf 399 SUPERFAMILY SSF52540 2 310 2.92E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03865 b4921873da6c7a58189e05ca00641dcf 399 Gene3D G3DSA:3.30.1220.10 241 376 7.6E-30 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CWR44_RS03865 b4921873da6c7a58189e05ca00641dcf 399 SMART SM00833 260 375 1.4E-43 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CWR44_RS03865 b4921873da6c7a58189e05ca00641dcf 399 Gene3D G3DSA:3.40.50.300 1 229 1.4E-53 T 28-03-2018 CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1181 1214 6.8E-4 T 28-03-2018 CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Pfam PF12892 Spy0128-like isopeptide containing domain 560 675 9.8E-16 T 28-03-2018 IPR022464 Streptococcal pilin isopeptide linker CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Pfam PF12892 Spy0128-like isopeptide containing domain 686 795 3.3E-9 T 28-03-2018 IPR022464 Streptococcal pilin isopeptide linker CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Pfam PF12892 Spy0128-like isopeptide containing domain 1011 1126 8.5E-16 T 28-03-2018 IPR022464 Streptococcal pilin isopeptide linker CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 847 950 1.4E-11 T 28-03-2018 IPR026345 Adhesin isopeptide-forming adherence domain CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Pfam PF00746 LPXTG cell wall anchor motif 1177 1214 4.3E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Gene3D G3DSA:3.10.20.10 542 595 5.7E-4 T 28-03-2018 CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Gene3D G3DSA:3.10.20.10 650 713 9.4E-12 T 28-03-2018 CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Gene3D G3DSA:3.10.20.10 1103 1151 0.11 T 28-03-2018 CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Gene3D G3DSA:3.10.20.10 964 1042 5.6E-8 T 28-03-2018 CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 5 39 2.5E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 607 675 3.2E-17 T 28-03-2018 IPR022464 Streptococcal pilin isopeptide linker CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 1054 1126 1.3E-21 T 28-03-2018 IPR022464 Streptococcal pilin isopeptide linker CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Pfam PF04650 YSIRK type signal peptide 4 29 3.4E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Gene3D G3DSA:2.60.40.1380 596 649 6.6E-5 T 28-03-2018 CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Gene3D G3DSA:2.60.40.1380 714 786 0.083 T 28-03-2018 CWR44_RS04500 ff56df1ff929c2981f968729c11b4ae8 1220 Gene3D G3DSA:2.60.40.1380 1043 1102 5.7E-5 T 28-03-2018 CWR44_RS02145 3d6c2f421a0336cd93a3bf1c25c46dd5 134 Gene3D G3DSA:3.10.129.10 8 134 6.2E-21 T 28-03-2018 CWR44_RS02145 3d6c2f421a0336cd93a3bf1c25c46dd5 134 SUPERFAMILY SSF54637 11 133 8.57E-27 T 28-03-2018 IPR029069 HotDog domain CWR44_RS02145 3d6c2f421a0336cd93a3bf1c25c46dd5 134 Pfam PF13279 Thioesterase-like superfamily 18 130 1.4E-10 T 28-03-2018 CWR44_RS00545 76c0d20f078c0442a3819e4c85a29ab1 649 Pfam PF04183 IucA / IucC family 194 436 1.4E-57 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CWR44_RS00545 76c0d20f078c0442a3819e4c85a29ab1 649 Pfam PF06276 Ferric iron reductase FhuF-like transporter 470 638 6.5E-29 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 Gene3D G3DSA:3.50.7.10 191 371 7.0E-94 T 28-03-2018 IPR027409 GroEL-like apical domain CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 Gene3D G3DSA:1.10.560.10 372 513 4.3E-26 T 28-03-2018 IPR027413 GroEL-like equatorial domain CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 Gene3D G3DSA:1.10.560.10 1 190 2.2E-43 T 28-03-2018 IPR027413 GroEL-like equatorial domain CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 SUPERFAMILY SSF48592 6 133 9.99E-76 T 28-03-2018 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 SUPERFAMILY SSF48592 404 518 9.99E-76 T 28-03-2018 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 40.7 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 PRINTS PR00298 60kDa chaperonin signature 82 109 2.5E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 PRINTS PR00298 60kDa chaperonin signature 396 417 2.5E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 PRINTS PR00298 60kDa chaperonin signature 348 373 2.5E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 PRINTS PR00298 60kDa chaperonin signature 266 289 2.5E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 PRINTS PR00298 60kDa chaperonin signature 26 52 2.5E-73 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 SUPERFAMILY SSF54849 137 202 4.58E-27 T 28-03-2018 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 523 4.6E-248 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 SUPERFAMILY SSF52029 182 374 8.52E-82 T 28-03-2018 IPR027409 GroEL-like apical domain CWR44_RS12610 cf2ddb7c190a50148fd7499f0ccb55e1 539 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 520 1.4E-98 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 4 42 5.6E-11 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2526 2605 4.8E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1085 1173 3.8E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1800 1894 7.3E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3955 4049 1.0E-8 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3245 3335 3.2E-8 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2795 2879 6.3E-8 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 4143 4233 1.5E-8 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2075 2163 1.6E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 728 829 4.8E-4 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 4050 4142 5.0E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3063 3155 3.9E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3606 3693 4.2E-9 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 4499 4594 8.1E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3875 3954 2.5E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2255 2345 2.5E-8 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3156 3244 2.7E-5 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 4595 4685 3.2E-8 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 4775 4864 6.8E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1984 2074 3.0E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2346 2434 7.2E-9 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2706 2794 2.6E-8 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 553 639 7.4E-5 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2435 2525 2.4E-9 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 4323 4415 4.2E-9 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1444 1534 2.6E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1255 1354 5.2E-8 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 4234 4322 3.5E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 988 1084 7.7E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2976 3062 1.0E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1715 1799 1.5E-5 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 4686 4774 5.1E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 4416 4498 3.5E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1174 1254 2.9E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1895 1983 9.8E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3694 3782 5.4E-8 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 640 727 0.18 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2164 2254 1.8E-5 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3513 3605 2.8E-9 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2880 2975 6.6E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3425 3512 7.7E-9 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1623 1714 8.5E-7 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1355 1443 1.8E-5 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3336 3424 2.4E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 1535 1622 4.2E-5 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 895 987 6.0E-4 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 4865 4991 9.6E-11 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 2606 2705 3.5E-9 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Gene3D G3DSA:2.60.40.1310 3783 3874 7.1E-6 T 28-03-2018 CWR44_RS10170 93a9c269caca6746fd51bb3d8c539026 5057 Pfam PF04650 YSIRK type signal peptide 5 30 5.1E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS06470 8c3c47ba0e30f4496ac9bb3c7ff14b73 309 SUPERFAMILY SSF52540 8 191 5.93E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06470 8c3c47ba0e30f4496ac9bb3c7ff14b73 309 SUPERFAMILY SSF90002 221 304 4.97E-10 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CWR44_RS06470 8c3c47ba0e30f4496ac9bb3c7ff14b73 309 Gene3D G3DSA:3.30.1220.10 205 308 1.8E-13 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CWR44_RS06470 8c3c47ba0e30f4496ac9bb3c7ff14b73 309 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 11 189 2.6E-47 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CWR44_RS06470 8c3c47ba0e30f4496ac9bb3c7ff14b73 309 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 221 305 8.4E-13 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CWR44_RS06470 8c3c47ba0e30f4496ac9bb3c7ff14b73 309 SMART SM00833 221 307 1.6E-13 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CWR44_RS06470 8c3c47ba0e30f4496ac9bb3c7ff14b73 309 Gene3D G3DSA:3.40.50.300 6 204 2.1E-34 T 28-03-2018 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 365 45.105 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 SUPERFAMILY SSF52540 3 303 1.55E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 Gene3D G3DSA:1.10.150.300 110 200 8.5E-31 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 Gene3D G3DSA:3.40.50.300 1 80 2.7E-7 T 28-03-2018 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 365 2.2E-156 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 Pfam PF06071 Protein of unknown function (DUF933) 281 364 1.5E-40 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.2E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 Pfam PF01926 50S ribosome-binding GTPase 5 115 4.3E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 Gene3D G3DSA:3.10.20.30 265 364 1.7E-45 T 28-03-2018 IPR012675 Beta-grasp domain CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 PIRSF PIRSF006641 1 365 1.8E-162 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CWR44_RS04605 9c155fd51488a3d612c7deb4b6e294a8 365 SUPERFAMILY SSF81271 281 362 4.36E-37 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CWR44_RS12315 05021f4aff72440b197ce0a16db2a346 128 Gene3D G3DSA:1.20.5.170 18 124 2.2E-4 T 28-03-2018 CWR44_RS10125 2ab826de764391991d6988b9c335d577 159 Gene3D G3DSA:3.40.430.10 1 159 4.6E-46 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CWR44_RS10125 2ab826de764391991d6988b9c335d577 159 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CWR44_RS10125 2ab826de764391991d6988b9c335d577 159 Pfam PF00186 Dihydrofolate reductase 3 157 3.4E-54 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWR44_RS10125 2ab826de764391991d6988b9c335d577 159 PRINTS PR00070 Dihydrofolate reductase signature 41 52 5.8E-12 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWR44_RS10125 2ab826de764391991d6988b9c335d577 159 PRINTS PR00070 Dihydrofolate reductase signature 28 36 5.8E-12 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWR44_RS10125 2ab826de764391991d6988b9c335d577 159 PRINTS PR00070 Dihydrofolate reductase signature 14 24 5.8E-12 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWR44_RS10125 2ab826de764391991d6988b9c335d577 159 PRINTS PR00070 Dihydrofolate reductase signature 89 103 5.8E-12 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWR44_RS10125 2ab826de764391991d6988b9c335d577 159 SUPERFAMILY SSF53597 2 158 2.1E-50 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CWR44_RS10125 2ab826de764391991d6988b9c335d577 159 PIRSF PIRSF000194 1 159 1.1E-49 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CWR44_RS11530 7b5dbc26d7dcfdf605778c46756d19af 555 Gene3D G3DSA:3.10.410.10 443 531 4.9E-39 T 28-03-2018 CWR44_RS11530 7b5dbc26d7dcfdf605778c46756d19af 555 Gene3D G3DSA:3.40.50.300 14 231 2.4E-88 T 28-03-2018 CWR44_RS11530 7b5dbc26d7dcfdf605778c46756d19af 555 Gene3D G3DSA:3.40.50.300 232 441 9.0E-77 T 28-03-2018 CWR44_RS11530 7b5dbc26d7dcfdf605778c46756d19af 555 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 3 555 48.844 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWR44_RS11530 7b5dbc26d7dcfdf605778c46756d19af 555 SUPERFAMILY SSF52540 6 553 2.39E-240 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11530 7b5dbc26d7dcfdf605778c46756d19af 555 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWR44_RS11530 7b5dbc26d7dcfdf605778c46756d19af 555 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 328 339 - T 28-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWR44_RS11530 7b5dbc26d7dcfdf605778c46756d19af 555 Pfam PF01268 Formate--tetrahydrofolate ligase 5 555 2.0E-265 T 28-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CWR44_RS12535 cfefd66c55ccc747dfaa9adbbc31ea8c 227 Gene3D G3DSA:1.10.287.70 5 142 0.14 T 28-03-2018 CWR44_RS12535 cfefd66c55ccc747dfaa9adbbc31ea8c 227 Pfam PF13346 ABC-2 family transporter protein 3 215 1.1E-13 T 28-03-2018 IPR025699 ABC-2 membrane transporter-like CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 Gene3D G3DSA:2.40.128.20 329 516 8.7E-66 T 28-03-2018 IPR012674 Calycin CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 Pfam PF01297 Zinc-uptake complex component A periplasmic 39 320 1.1E-66 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 SUPERFAMILY SSF50814 332 516 7.31E-76 T 28-03-2018 IPR012674 Calycin CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 PRINTS PR00690 Adhesin family signature 80 97 1.2E-8 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 PRINTS PR00690 Adhesin family signature 259 277 1.2E-8 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 PRINTS PR00690 Adhesin family signature 36 54 1.2E-8 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 PRINTS PR00690 Adhesin family signature 67 80 1.2E-8 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 PRINTS PR00691 Adhesin B signature 36 57 3.5E-9 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 PRINTS PR00691 Adhesin B signature 255 272 3.5E-9 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 PRINTS PR00691 Adhesin B signature 80 99 3.5E-9 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 PRINTS PR00691 Adhesin B signature 300 318 3.5E-9 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 PRINTS PR00691 Adhesin B signature 61 79 3.5E-9 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 Pfam PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment 337 516 4.3E-79 T 28-03-2018 IPR015304 ZinT domain GO:0008270 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 Gene3D G3DSA:3.40.50.1980 200 322 8.7E-28 T 28-03-2018 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 Gene3D G3DSA:3.40.50.1980 25 199 8.8E-51 T 28-03-2018 CWR44_RS01555 f2a62250fff637624fbfbc24a91bdea1 516 SUPERFAMILY SSF53807 35 321 1.57E-76 T 28-03-2018 CWR44_RS09035 fb821ffdfbcc1f4c3651ac4616edc7d6 411 Pfam PF03796 DnaB-like helicase C terminal domain 158 410 2.1E-70 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CWR44_RS09035 fb821ffdfbcc1f4c3651ac4616edc7d6 411 Gene3D G3DSA:3.40.50.300 142 411 2.6E-41 T 28-03-2018 CWR44_RS09035 fb821ffdfbcc1f4c3651ac4616edc7d6 411 SUPERFAMILY SSF52540 157 405 1.56E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 Gene3D G3DSA:3.90.190.20 252 380 1.3E-4 T 28-03-2018 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 SUPERFAMILY SSF53623 104 235 1.16E-19 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 SUPERFAMILY SSF53623 32 75 1.16E-19 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 258 275 5.8E-67 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 360 376 5.8E-67 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 196 213 5.8E-67 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 57 74 5.8E-67 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 140 155 5.8E-67 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 162 179 5.8E-67 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 293 308 5.8E-67 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 77 95 5.8E-67 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 111 126 5.8E-67 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 PRINTS PR01758 Capsule biosynthesis protein CapB signature 34 50 5.8E-67 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 Gene3D G3DSA:3.40.1190.10 18 243 1.1E-18 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 Pfam PF08245 Mur ligase middle domain 37 198 1.4E-11 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CWR44_RS02105 a614ec4cd93ca456b9478f12f5b651f1 385 TIGRFAM TIGR04012 poly_gGlu_PgsB: poly-gamma-glutamate synthase PgsB 2 381 4.7E-177 T 28-03-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 CWR44_RS03050 f8913b6ed95c14ae3f4a91eea55cc05f 319 SMART SM00062 49 295 6.3E-4 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR44_RS03050 f8913b6ed95c14ae3f4a91eea55cc05f 319 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 1 278 4.2E-75 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 CWR44_RS03050 f8913b6ed95c14ae3f4a91eea55cc05f 319 SUPERFAMILY SSF53850 46 313 1.06E-49 T 28-03-2018 CWR44_RS03050 f8913b6ed95c14ae3f4a91eea55cc05f 319 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 54 305 5.8E-70 T 28-03-2018 CWR44_RS03050 f8913b6ed95c14ae3f4a91eea55cc05f 319 Gene3D G3DSA:3.40.190.10 34 144 6.0E-11 T 28-03-2018 CWR44_RS03050 f8913b6ed95c14ae3f4a91eea55cc05f 319 Gene3D G3DSA:3.40.190.10 152 301 4.8E-37 T 28-03-2018 CWR44_RS04355 8ec6224fae0f05ac032cacf9c71c2774 233 Gene3D G3DSA:3.40.50.2300 2 126 1.9E-37 T 28-03-2018 CWR44_RS04355 8ec6224fae0f05ac032cacf9c71c2774 233 SMART SM00862 153 229 9.3E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS04355 8ec6224fae0f05ac032cacf9c71c2774 233 Pfam PF00072 Response regulator receiver domain 5 114 5.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS04355 8ec6224fae0f05ac032cacf9c71c2774 233 Gene3D G3DSA:1.10.10.10 127 233 1.1E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04355 8ec6224fae0f05ac032cacf9c71c2774 233 SMART SM00448 3 113 4.9E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS04355 8ec6224fae0f05ac032cacf9c71c2774 233 SUPERFAMILY SSF52172 3 126 2.56E-42 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS04355 8ec6224fae0f05ac032cacf9c71c2774 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 9.3E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS04355 8ec6224fae0f05ac032cacf9c71c2774 233 SUPERFAMILY SSF46894 131 229 1.73E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CWR44_RS07505 65d58b911ed6a48251696a4b8ba8bd15 131 Pfam PF03960 ArsC family 6 113 8.5E-24 T 28-03-2018 IPR006660 Arsenate reductase-like CWR44_RS07505 65d58b911ed6a48251696a4b8ba8bd15 131 SUPERFAMILY SSF52833 1 129 1.43E-39 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS07505 65d58b911ed6a48251696a4b8ba8bd15 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 7.8E-37 T 28-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CWR44_RS07505 65d58b911ed6a48251696a4b8ba8bd15 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 37.482 T 28-03-2018 IPR023731 Regulatory protein Spx GO:0045892 CWR44_RS07505 65d58b911ed6a48251696a4b8ba8bd15 131 Gene3D G3DSA:3.40.30.10 1 131 1.4E-39 T 28-03-2018 CWR44_RS11575 da166cee0b915d93d246a7cf6e32ec59 1297 Gene3D G3DSA:1.10.10.10 1230 1283 4.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11575 da166cee0b915d93d246a7cf6e32ec59 1297 Pfam PF01580 FtsK/SpoIIIE family 1083 1133 2.1E-13 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CWR44_RS11575 da166cee0b915d93d246a7cf6e32ec59 1297 Pfam PF01580 FtsK/SpoIIIE family 945 1081 1.7E-45 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CWR44_RS11575 da166cee0b915d93d246a7cf6e32ec59 1297 Gene3D G3DSA:3.40.50.300 742 1229 7.3E-50 T 28-03-2018 CWR44_RS11575 da166cee0b915d93d246a7cf6e32ec59 1297 SUPERFAMILY SSF46785 1228 1293 4.81E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS11575 da166cee0b915d93d246a7cf6e32ec59 1297 SMART SM00843 1227 1292 1.5E-31 T 28-03-2018 IPR018541 FtsK gamma domain CWR44_RS11575 da166cee0b915d93d246a7cf6e32ec59 1297 Pfam PF09397 Ftsk gamma domain 1229 1290 1.1E-25 T 28-03-2018 IPR018541 FtsK gamma domain CWR44_RS11575 da166cee0b915d93d246a7cf6e32ec59 1297 SUPERFAMILY SSF52540 918 1206 7.7E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00135 c1868717619ca7d0ce9cb3d4b7bf8605 77 Pfam PF06612 Protein of unknown function (DUF1146) 17 63 3.7E-18 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CWR44_RS00135 c1868717619ca7d0ce9cb3d4b7bf8605 77 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 9 76 6.9E-16 T 28-03-2018 IPR009526 Protein of unknown function DUF1146 CWR44_RS03135 35ab09577d048bada97c57ef12b51d58 325 SUPERFAMILY SSF63829 11 323 1.72E-63 T 28-03-2018 CWR44_RS03135 35ab09577d048bada97c57ef12b51d58 325 Gene3D G3DSA:2.120.10.30 1 325 3.7E-51 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CWR44_RS03135 35ab09577d048bada97c57ef12b51d58 325 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 46 271 2.5E-32 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CWR44_RS11175 7452bcaf8bb14bd7d85ad80458e45b62 231 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 11 86 3.6E-16 T 28-03-2018 IPR010627 Peptidase A24A, N-terminal CWR44_RS03730 36084224ab6f63b07d949d05665c6ed1 748 SUPERFAMILY SSF53474 370 740 1.41E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS03730 36084224ab6f63b07d949d05665c6ed1 748 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 2 37 4.7E-14 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS03730 36084224ab6f63b07d949d05665c6ed1 748 Gene3D G3DSA:3.40.50.1820 361 748 2.4E-97 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS03730 36084224ab6f63b07d949d05665c6ed1 748 Pfam PF04650 YSIRK type signal peptide 4 27 2.2E-10 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS07335 2d19a188e1fff4daff69da497ebcc752 198 PIRSF PIRSF001467 144 198 1.6E-9 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CWR44_RS07335 2d19a188e1fff4daff69da497ebcc752 198 PIRSF PIRSF001467 6 124 7.7E-43 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CWR44_RS07335 2d19a188e1fff4daff69da497ebcc752 198 SUPERFAMILY SSF50891 148 195 3.07E-58 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS07335 2d19a188e1fff4daff69da497ebcc752 198 SUPERFAMILY SSF50891 18 119 3.07E-58 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS07335 2d19a188e1fff4daff69da497ebcc752 198 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 18 194 4.4E-47 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWR44_RS07335 2d19a188e1fff4daff69da497ebcc752 198 Gene3D G3DSA:2.40.100.10 2 198 1.5E-65 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS07335 2d19a188e1fff4daff69da497ebcc752 198 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 99 114 4.0E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWR44_RS07335 2d19a188e1fff4daff69da497ebcc752 198 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 57 69 4.0E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWR44_RS07335 2d19a188e1fff4daff69da497ebcc752 198 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 31 46 4.0E-20 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CWR44_RS04620 f3c1e837178fd16aa61a162ae713bac0 98 Gene3D G3DSA:3.30.70.60 1 98 9.4E-27 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CWR44_RS04620 f3c1e837178fd16aa61a162ae713bac0 98 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 95 3.0E-27 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04620 f3c1e837178fd16aa61a162ae713bac0 98 Pfam PF01250 Ribosomal protein S6 4 93 1.0E-23 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04620 f3c1e837178fd16aa61a162ae713bac0 98 SUPERFAMILY SSF54995 1 96 3.01E-30 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04620 f3c1e837178fd16aa61a162ae713bac0 98 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 96 22.061 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CWR44_RS08820 ab6014e4d66bdcd8dd6f6f48367cc99d 130 SUPERFAMILY SSF47413 2 71 7.19E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS08820 ab6014e4d66bdcd8dd6f6f48367cc99d 130 Gene3D G3DSA:1.10.260.40 1 83 1.3E-11 T 28-03-2018 CWR44_RS08820 ab6014e4d66bdcd8dd6f6f48367cc99d 130 Pfam PF13413 Helix-turn-helix domain 8 67 1.5E-16 T 28-03-2018 CWR44_RS06610 976ec04d804f28621449f95c87cb86fb 645 PIRSF PIRSF005091 1 624 1.6E-178 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like CWR44_RS06610 976ec04d804f28621449f95c87cb86fb 645 Gene3D G3DSA:3.40.720.10 239 549 3.4E-34 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWR44_RS06610 976ec04d804f28621449f95c87cb86fb 645 SUPERFAMILY SSF53649 245 637 2.62E-65 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR44_RS06610 976ec04d804f28621449f95c87cb86fb 645 Pfam PF00884 Sulfatase 247 539 8.9E-29 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CWR44_RS12955 16fc4532bb58a812c76da46bfb80bc79 605 SUPERFAMILY SSF53649 198 584 1.94E-64 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR44_RS12955 16fc4532bb58a812c76da46bfb80bc79 605 Pfam PF00884 Sulfatase 200 492 7.6E-29 T 28-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CWR44_RS12955 16fc4532bb58a812c76da46bfb80bc79 605 PIRSF PIRSF005091 1 577 3.7E-172 T 28-03-2018 IPR012160 Lipoteichoic acid synthase-like CWR44_RS12955 16fc4532bb58a812c76da46bfb80bc79 605 Gene3D G3DSA:3.40.720.10 192 502 2.9E-34 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWR44_RS12285 f51b32856fd8f5251b2971a7eb35cd17 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 141 2.5E-35 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR44_RS12285 f51b32856fd8f5251b2971a7eb35cd17 154 SUPERFAMILY SSF52788 1 145 6.41E-42 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR44_RS12285 f51b32856fd8f5251b2971a7eb35cd17 154 Gene3D G3DSA:3.40.50.2300 1 153 6.3E-45 T 28-03-2018 CWR44_RS12285 f51b32856fd8f5251b2971a7eb35cd17 154 SMART SM00226 2 144 1.2E-39 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CWR44_RS12285 f51b32856fd8f5251b2971a7eb35cd17 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 78 93 1.2E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR44_RS12285 f51b32856fd8f5251b2971a7eb35cd17 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 1.2E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR44_RS12285 f51b32856fd8f5251b2971a7eb35cd17 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 118 133 1.2E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR44_RS12285 f51b32856fd8f5251b2971a7eb35cd17 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 46 62 1.2E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CWR44_RS02605 09ac083de3f697ff5e886dd538004e41 289 Pfam PF01925 Sulfite exporter TauE/SafE 8 245 1.2E-36 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CWR44_RS01690 2392a5b45cb1edda06dbdc8c89daf00f 283 Gene3D G3DSA:3.40.50.720 1 281 6.9E-29 T 28-03-2018 CWR44_RS01690 2392a5b45cb1edda06dbdc8c89daf00f 283 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 222 4.0E-18 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CWR44_RS01690 2392a5b45cb1edda06dbdc8c89daf00f 283 SUPERFAMILY SSF51735 1 255 1.89E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10370 19fa9d57b1244f4d9ce8b8bef3db82de 317 Pfam PF14493 Helix-turn-helix domain 222 306 6.7E-13 T 28-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CWR44_RS10370 19fa9d57b1244f4d9ce8b8bef3db82de 317 PIRSF PIRSF021350 1 316 5.8E-79 T 28-03-2018 IPR008308 Uncharacterised conserved protein UCP021350 CWR44_RS05315 2e795275a2086ba6f44f778e048e70f6 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 99 117 - T 28-03-2018 IPR019897 RidA, conserved site CWR44_RS05315 2e795275a2086ba6f44f778e048e70f6 126 Gene3D G3DSA:3.30.1330.40 1 125 3.2E-45 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CWR44_RS05315 2e795275a2086ba6f44f778e048e70f6 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 1 120 4.1E-53 T 28-03-2018 IPR006056 RidA family CWR44_RS05315 2e795275a2086ba6f44f778e048e70f6 126 SUPERFAMILY SSF55298 2 123 2.2E-47 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CWR44_RS05315 2e795275a2086ba6f44f778e048e70f6 126 Pfam PF01042 Endoribonuclease L-PSP 7 120 6.0E-46 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CWR44_RS00280 010844291982adcf14b767b1b8ca5b4f 266 TIGRFAM TIGR00555 panK_eukar: pantothenate kinase 1 264 3.8E-85 T 28-03-2018 IPR004567 Type II pantothenate kinase GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|Reactome: R-HSA-196783 CWR44_RS00280 010844291982adcf14b767b1b8ca5b4f 266 Gene3D G3DSA:3.30.420.40 1 132 9.8E-4 T 28-03-2018 CWR44_RS00280 010844291982adcf14b767b1b8ca5b4f 266 Pfam PF03630 Fumble 89 263 1.7E-21 T 28-03-2018 IPR004567 Type II pantothenate kinase GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|Reactome: R-HSA-196783 CWR44_RS00280 010844291982adcf14b767b1b8ca5b4f 266 Hamap MF_01273 Type II pantothenate kinase [coaW]. 1 265 48.785 T 28-03-2018 IPR011602 Type II pantothenate kinase, bacterial GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CWR44_RS00280 010844291982adcf14b767b1b8ca5b4f 266 PIRSF PIRSF036940 1 266 2.2E-126 T 28-03-2018 IPR011602 Type II pantothenate kinase, bacterial GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CWR44_RS00280 010844291982adcf14b767b1b8ca5b4f 266 SUPERFAMILY SSF53067 1 265 2.0E-59 T 28-03-2018 CWR44_RS09290 474af33f410a8f4e87af422ff670afcf 245 PIRSF PIRSF006648 2 243 5.9E-22 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CWR44_RS09290 474af33f410a8f4e87af422ff670afcf 245 Pfam PF12698 ABC-2 family transporter protein 42 237 5.8E-20 T 28-03-2018 CWR44_RS00890 2771a473a046cfef31df4fa73027537a 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 1 77 1.1E-24 T 28-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CWR44_RS00890 2771a473a046cfef31df4fa73027537a 77 Gene3D G3DSA:3.10.20.30 1 77 1.1E-21 T 28-03-2018 IPR012675 Beta-grasp domain CWR44_RS00890 2771a473a046cfef31df4fa73027537a 77 SUPERFAMILY SSF54285 1 75 7.12E-17 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CWR44_RS00890 2771a473a046cfef31df4fa73027537a 77 Pfam PF02597 ThiS family 3 77 4.3E-17 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CWR44_RS03030 e8f3d4af93c0b929b6bb366443213346 125 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 18 123 6.0E-48 T 28-03-2018 CWR44_RS05115 a39de731ad3b86e032ab88b16420d64e 298 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 28 46 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CWR44_RS05115 a39de731ad3b86e032ab88b16420d64e 298 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 5 282 2.8E-62 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR44_RS05115 a39de731ad3b86e032ab88b16420d64e 298 Gene3D G3DSA:3.40.50.1100 129 296 2.6E-43 T 28-03-2018 CWR44_RS05115 a39de731ad3b86e032ab88b16420d64e 298 SUPERFAMILY SSF53686 4 293 3.27E-81 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR44_RS05115 a39de731ad3b86e032ab88b16420d64e 298 Gene3D G3DSA:3.40.50.1100 18 128 9.2E-32 T 28-03-2018 CWR44_RS06315 997ab8a9353062a736079f925b65e900 168 SUPERFAMILY SSF55729 3 167 1.27E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS06315 997ab8a9353062a736079f925b65e900 168 Gene3D G3DSA:3.40.630.30 2 168 9.4E-30 T 28-03-2018 CWR44_RS06315 997ab8a9353062a736079f925b65e900 168 Pfam PF13420 Acetyltransferase (GNAT) domain 5 160 1.1E-18 T 28-03-2018 CWR44_RS01580 b4e5f38242698261ec1b7f6c7f6c728a 239 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 128 1.8E-24 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CWR44_RS01580 b4e5f38242698261ec1b7f6c7f6c728a 239 SUPERFAMILY SSF161098 23 219 3.01E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS01580 b4e5f38242698261ec1b7f6c7f6c728a 239 Gene3D G3DSA:1.10.3720.10 2 238 1.2E-41 T 28-03-2018 CWR44_RS01580 b4e5f38242698261ec1b7f6c7f6c728a 239 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 230 1.2E-24 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS02075 5ced2039b2c5e2107c5ae3326b527018 228 Gene3D G3DSA:3.30.1330.90 19 145 4.4E-19 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CWR44_RS02075 5ced2039b2c5e2107c5ae3326b527018 228 PIRSF PIRSF036692 7 228 2.3E-51 T 28-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CWR44_RS02075 5ced2039b2c5e2107c5ae3326b527018 228 Pfam PF03315 Serine dehydratase beta chain 11 87 5.6E-9 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CWR44_RS02075 5ced2039b2c5e2107c5ae3326b527018 228 SUPERFAMILY SSF143548 25 142 8.5E-26 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CWR44_RS04455 ba100a564c0fb7142b460e6c42c84038 114 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 109 19.598 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWR44_RS04455 ba100a564c0fb7142b460e6c42c84038 114 SUPERFAMILY SSF54211 2 112 3.29E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CWR44_RS04455 ba100a564c0fb7142b460e6c42c84038 114 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 114 2.0E-48 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWR44_RS04455 ba100a564c0fb7142b460e6c42c84038 114 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 50 64 - T 28-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CWR44_RS04455 ba100a564c0fb7142b460e6c42c84038 114 Pfam PF00825 Ribonuclease P 2 105 1.0E-30 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWR44_RS04455 ba100a564c0fb7142b460e6c42c84038 114 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 3 104 3.5E-28 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CWR44_RS04455 ba100a564c0fb7142b460e6c42c84038 114 Gene3D G3DSA:3.30.230.10 1 113 1.3E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CWR44_RS02005 6e03c71ad00b7d5a87f62838a44cebc9 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 2.8E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS02005 6e03c71ad00b7d5a87f62838a44cebc9 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 2.8E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS02005 6e03c71ad00b7d5a87f62838a44cebc9 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 2.8E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS02005 6e03c71ad00b7d5a87f62838a44cebc9 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CWR44_RS02005 6e03c71ad00b7d5a87f62838a44cebc9 144 Pfam PF01047 MarR family 34 91 1.5E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS02005 6e03c71ad00b7d5a87f62838a44cebc9 144 SMART SM00347 27 127 4.0E-22 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS02005 6e03c71ad00b7d5a87f62838a44cebc9 144 Gene3D G3DSA:1.10.10.10 2 144 3.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02005 6e03c71ad00b7d5a87f62838a44cebc9 144 SUPERFAMILY SSF46785 6 140 1.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04790 6ddd27a9dca361fd890101a2391c3314 585 Pfam PF05569 BlaR1 peptidase M56 4 298 3.2E-95 T 28-03-2018 IPR008756 Peptidase M56 CWR44_RS04790 6ddd27a9dca361fd890101a2391c3314 585 Gene3D G3DSA:3.40.710.10 331 584 1.6E-24 T 28-03-2018 CWR44_RS04790 6ddd27a9dca361fd890101a2391c3314 585 Pfam PF00905 Penicillin binding protein transpeptidase domain 362 577 1.2E-39 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR44_RS04790 6ddd27a9dca361fd890101a2391c3314 585 Gene3D G3DSA:3.30.2010.10 146 219 5.6E-4 T 28-03-2018 CWR44_RS04790 6ddd27a9dca361fd890101a2391c3314 585 SUPERFAMILY SSF56601 346 579 6.22E-30 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR44_RS11090 7de28548bc3e4abed83c148de585ab05 86 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 83 9.3E-26 T 28-03-2018 IPR003849 Preprotein translocase YajC CWR44_RS11090 7de28548bc3e4abed83c148de585ab05 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 23 41 6.9E-13 T 28-03-2018 IPR003849 Preprotein translocase YajC CWR44_RS11090 7de28548bc3e4abed83c148de585ab05 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 3 23 6.9E-13 T 28-03-2018 IPR003849 Preprotein translocase YajC CWR44_RS11090 7de28548bc3e4abed83c148de585ab05 86 Pfam PF02699 Preprotein translocase subunit 6 81 5.1E-27 T 28-03-2018 IPR003849 Preprotein translocase YajC CWR44_RS11090 7de28548bc3e4abed83c148de585ab05 86 Gene3D G3DSA:2.40.50.140 47 86 7.3E-5 T 28-03-2018 CWR44_RS11090 7de28548bc3e4abed83c148de585ab05 86 SMART SM01323 1 84 2.2E-34 T 28-03-2018 IPR003849 Preprotein translocase YajC CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 SUPERFAMILY SSF50249 192 276 4.12E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 SUPERFAMILY SSF50249 257 359 4.4E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 PRINTS PR00681 Ribosomal protein S1 signature 128 145 6.0E-42 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 PRINTS PR00681 Ribosomal protein S1 signature 16 34 6.0E-42 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 PRINTS PR00681 Ribosomal protein S1 signature 214 235 6.0E-42 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 PRINTS PR00681 Ribosomal protein S1 signature 111 127 6.0E-42 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 PRINTS PR00681 Ribosomal protein S1 signature 331 349 6.0E-42 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 PRINTS PR00681 Ribosomal protein S1 signature 292 311 6.0E-42 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 PRINTS PR00681 Ribosomal protein S1 signature 157 177 6.0E-42 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 SUPERFAMILY SSF50249 93 176 6.86E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 Gene3D G3DSA:2.40.50.140 279 376 2.8E-23 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 SUPERFAMILY SSF50249 10 116 9.29E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 SMART SM00316 192 262 3.3E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 SMART SM00316 277 348 1.4E-23 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 SMART SM00316 14 90 4.1E-17 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 SMART SM00316 106 173 1.1E-10 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 Gene3D G3DSA:2.40.50.140 97 179 1.1E-14 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 Gene3D G3DSA:2.40.50.140 183 267 2.4E-26 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 Gene3D G3DSA:2.40.50.140 6 96 5.1E-18 T 28-03-2018 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 Pfam PF00575 S1 RNA binding domain 14 80 7.6E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 Pfam PF00575 S1 RNA binding domain 192 262 3.2E-26 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 Pfam PF00575 S1 RNA binding domain 107 173 4.6E-14 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS10340 47becd3306debcfea7f2d851759d71a7 392 Pfam PF00575 S1 RNA binding domain 277 348 3.9E-22 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS05145 0aa179ec64740684061c76998c122843 264 Pfam PF07907 YibE/F-like protein 5 243 7.6E-67 T 28-03-2018 IPR012507 YibE/F-like CWR44_RS05145 0aa179ec64740684061c76998c122843 264 PIRSF PIRSF031503 1 260 1.0E-110 T 28-03-2018 IPR014564 Uncharacterised conserved protein UCP031503, transmembrane CWR44_RS07945 16e5213168fbc0fc3ef49747ecd8e860 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 327 8.9E-36 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CWR44_RS00930 6425cceccbeff424e3e3405f2ceafb21 223 Gene3D G3DSA:1.10.3720.10 4 221 1.9E-35 T 28-03-2018 CWR44_RS00930 6425cceccbeff424e3e3405f2ceafb21 223 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 8 216 3.3E-73 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CWR44_RS00930 6425cceccbeff424e3e3405f2ceafb21 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 23 208 4.4E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS00930 6425cceccbeff424e3e3405f2ceafb21 223 SUPERFAMILY SSF161098 5 213 6.67E-45 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS06170 1752a396746808f277a2cc5658dc246d 100 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 35 86 2.5E-14 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CWR44_RS06170 1752a396746808f277a2cc5658dc246d 100 PIRSF PIRSF028784 2 96 1.9E-25 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CWR44_RS07885 87b75170cbc323ef74763d7bcff4206f 467 SMART SM00382 28 214 6.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS07885 87b75170cbc323ef74763d7bcff4206f 467 SMART SM00382 277 458 1.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS07885 87b75170cbc323ef74763d7bcff4206f 467 Pfam PF00005 ABC transporter 271 408 2.7E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS07885 87b75170cbc323ef74763d7bcff4206f 467 Pfam PF00005 ABC transporter 20 158 1.3E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS07885 87b75170cbc323ef74763d7bcff4206f 467 SUPERFAMILY SSF52540 2 224 5.09E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07885 87b75170cbc323ef74763d7bcff4206f 467 Gene3D G3DSA:3.40.50.300 243 466 1.8E-42 T 28-03-2018 CWR44_RS07885 87b75170cbc323ef74763d7bcff4206f 467 Gene3D G3DSA:3.40.50.300 1 228 2.2E-48 T 28-03-2018 CWR44_RS07885 87b75170cbc323ef74763d7bcff4206f 467 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS07885 87b75170cbc323ef74763d7bcff4206f 467 SUPERFAMILY SSF52540 239 462 3.93E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 101 4.3E-36 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 SUPERFAMILY SSF51735 1 152 6.76E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 Gene3D G3DSA:3.40.50.720 1 162 3.4E-66 T 28-03-2018 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 SUPERFAMILY SSF55347 153 312 2.98E-65 T 28-03-2018 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 159 311 3.9E-64 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 PIRSF PIRSF000149 1 332 4.5E-124 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 322 2.3E-126 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 SMART SM00846 3 153 5.9E-71 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 5.5E-36 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 5.5E-36 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 5.5E-36 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 5.5E-36 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 267 282 5.5E-36 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CWR44_RS11300 fdbb7ac8a89e66892efe3bf3f12d99d2 341 Gene3D G3DSA:3.30.360.10 163 313 9.2E-62 T 28-03-2018 CWR44_RS02355 c2074c70ba9c6c4676c4420d9c75f9c0 211 SUPERFAMILY SSF54427 13 140 9.74E-16 T 28-03-2018 IPR032710 NTF2-like domain CWR44_RS02355 c2074c70ba9c6c4676c4420d9c75f9c0 211 Gene3D G3DSA:3.10.450.50 6 136 1.7E-7 T 28-03-2018 CWR44_RS04825 b96fa098238b33ce9c2b70a964b28b81 176 Pfam PF00583 Acetyltransferase (GNAT) family 27 132 4.2E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS04825 b96fa098238b33ce9c2b70a964b28b81 176 SUPERFAMILY SSF55729 4 140 3.99E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS04825 b96fa098238b33ce9c2b70a964b28b81 176 Gene3D G3DSA:3.40.630.30 1 140 2.2E-17 T 28-03-2018 CWR44_RS10040 2a3ebd4f7e4455b6f6e2db64aa296484 263 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 179 257 1.8E-6 T 28-03-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal CWR44_RS10040 2a3ebd4f7e4455b6f6e2db64aa296484 263 Pfam PF07728 AAA domain (dynein-related subfamily) 26 164 2.1E-29 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CWR44_RS10040 2a3ebd4f7e4455b6f6e2db64aa296484 263 Gene3D G3DSA:3.40.50.300 17 170 1.5E-29 T 28-03-2018 CWR44_RS10040 2a3ebd4f7e4455b6f6e2db64aa296484 263 SMART SM00382 23 173 0.0012 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS10040 2a3ebd4f7e4455b6f6e2db64aa296484 263 SUPERFAMILY SSF52540 23 244 2.52E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10040 2a3ebd4f7e4455b6f6e2db64aa296484 263 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 100 118 2.0E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS10040 2a3ebd4f7e4455b6f6e2db64aa296484 263 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 27 45 2.0E-5 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS09715 17092c9414620c0260d00adad92979eb 491 Pfam PF05709 Phage tail protein 26 491 5.5E-51 T 28-03-2018 IPR008841 Siphovirus-type tail component CWR44_RS09715 17092c9414620c0260d00adad92979eb 491 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 4 127 1.1E-24 T 28-03-2018 IPR006520 Streptococcus phage 7201, Orf34, N-terminal CWR44_RS13145 4492a88fd5d8cb3f2b728c2333a9e720 161 Gene3D G3DSA:1.10.10.10 1 41 7.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS05250 c71ca91a01040fb35568a9cfd6d23d3e 308 Pfam PF13177 DNA polymerase III, delta subunit 4 149 1.6E-43 T 28-03-2018 CWR44_RS05250 c71ca91a01040fb35568a9cfd6d23d3e 308 SUPERFAMILY SSF52540 8 166 1.28E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05250 c71ca91a01040fb35568a9cfd6d23d3e 308 Gene3D G3DSA:3.40.50.300 2 148 1.8E-28 T 28-03-2018 CWR44_RS05250 c71ca91a01040fb35568a9cfd6d23d3e 308 Gene3D G3DSA:1.20.272.10 190 306 6.5E-18 T 28-03-2018 CWR44_RS05250 c71ca91a01040fb35568a9cfd6d23d3e 308 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 217 304 1.8E-5 T 28-03-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS07310 d2360b3a5889e1a8913fd94190f7bf55 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 378 404 3.7E-15 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS07310 d2360b3a5889e1a8913fd94190f7bf55 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 164 188 3.7E-15 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS07310 d2360b3a5889e1a8913fd94190f7bf55 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 326 345 3.7E-15 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS07310 d2360b3a5889e1a8913fd94190f7bf55 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 134 153 3.7E-15 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS07310 d2360b3a5889e1a8913fd94190f7bf55 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 238 262 3.7E-15 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS07310 d2360b3a5889e1a8913fd94190f7bf55 499 Pfam PF00361 Proton-conducting membrane transporter 130 418 1.1E-48 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS06480 7a9dc6cacdcbf34403280b01290b10f1 521 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 45 515 2.7E-78 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CWR44_RS06480 7a9dc6cacdcbf34403280b01290b10f1 521 PIRSF PIRSF002457 13 521 1.2E-133 T 28-03-2018 IPR030676 Citrate carrier CitT-related CWR44_RS06480 7a9dc6cacdcbf34403280b01290b10f1 521 Pfam PF00939 Sodium:sulfate symporter transmembrane region 32 520 1.5E-109 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CWR44_RS09065 015e898d94bd624c67e39d2001b8d065 107 Pfam PF11753 Protein of unknwon function (DUF3310) 39 98 1.5E-14 T 28-03-2018 IPR021739 SaV-like CWR44_RS10900 6769d580dcc5d347fba3ca82dfd78ae6 268 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 265 5.6E-82 T 28-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWR44_RS10900 6769d580dcc5d347fba3ca82dfd78ae6 268 SUPERFAMILY SSF53223 2 99 1.96E-33 T 28-03-2018 CWR44_RS10900 6769d580dcc5d347fba3ca82dfd78ae6 268 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 109 186 1.6E-10 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CWR44_RS10900 6769d580dcc5d347fba3ca82dfd78ae6 268 SUPERFAMILY SSF51735 100 263 1.58E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10900 6769d580dcc5d347fba3ca82dfd78ae6 268 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 263 31.324 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWR44_RS10900 6769d580dcc5d347fba3ca82dfd78ae6 268 Gene3D G3DSA:3.40.50.10860 1 110 1.5E-39 T 28-03-2018 CWR44_RS10900 6769d580dcc5d347fba3ca82dfd78ae6 268 Gene3D G3DSA:3.40.50.720 111 268 3.9E-22 T 28-03-2018 CWR44_RS10900 6769d580dcc5d347fba3ca82dfd78ae6 268 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 5 87 4.3E-29 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CWR44_RS04220 b6d423acc08694b1a6d2880a776bba2d 103 Pfam PF06124 Staphylococcal protein of unknown function (DUF960) 4 102 4.3E-28 T 28-03-2018 IPR009303 Protein of unknown function DUF960 CWR44_RS04220 b6d423acc08694b1a6d2880a776bba2d 103 Gene3D G3DSA:3.10.450.150 1 102 1.3E-32 T 28-03-2018 CWR44_RS05360 a826e58697cb0bcff9a130b479f80bfe 92 Pfam PF01479 S4 domain 1 47 7.4E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS05360 a826e58697cb0bcff9a130b479f80bfe 92 SMART SM00363 1 63 1.1E-6 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS05360 a826e58697cb0bcff9a130b479f80bfe 92 PIRSF PIRSF038881 1 89 3.7E-33 T 28-03-2018 IPR025490 RNA-binding protein, HP1423 type CWR44_RS05360 a826e58697cb0bcff9a130b479f80bfe 92 SUPERFAMILY SSF55174 1 76 9.68E-19 T 28-03-2018 CWR44_RS05360 a826e58697cb0bcff9a130b479f80bfe 92 Gene3D G3DSA:3.10.290.10 1 92 5.7E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS06670 3f3fdd4b8847e7db67594af9b30c1fa6 501 SUPERFAMILY SSF103473 15 211 6.54E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS06670 3f3fdd4b8847e7db67594af9b30c1fa6 501 SUPERFAMILY SSF103473 277 494 6.54E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS06670 3f3fdd4b8847e7db67594af9b30c1fa6 501 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 497 1.9E-115 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CWR44_RS06670 3f3fdd4b8847e7db67594af9b30c1fa6 501 Gene3D G3DSA:1.20.1250.20 285 498 7.3E-16 T 28-03-2018 CWR44_RS06670 3f3fdd4b8847e7db67594af9b30c1fa6 501 Pfam PF00854 POT family 100 464 1.8E-62 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CWR44_RS06670 3f3fdd4b8847e7db67594af9b30c1fa6 501 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 159 171 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CWR44_RS06670 3f3fdd4b8847e7db67594af9b30c1fa6 501 Gene3D G3DSA:1.20.1250.20 15 213 3.0E-21 T 28-03-2018 CWR44_RS12180 dfaa5c196b7acc602a00e94ebffb3977 316 Gene3D G3DSA:3.40.50.720 1 109 7.8E-18 T 28-03-2018 CWR44_RS12180 dfaa5c196b7acc602a00e94ebffb3977 316 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 277 9.6E-43 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWR44_RS12180 dfaa5c196b7acc602a00e94ebffb3977 316 SUPERFAMILY SSF51735 98 277 5.31E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS12180 dfaa5c196b7acc602a00e94ebffb3977 316 SUPERFAMILY SSF52283 37 114 1.04E-15 T 28-03-2018 CWR44_RS12180 dfaa5c196b7acc602a00e94ebffb3977 316 Gene3D G3DSA:3.40.50.720 110 279 1.7E-35 T 28-03-2018 CWR44_RS12180 dfaa5c196b7acc602a00e94ebffb3977 316 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 18 128 1.0E-12 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CWR44_RS12180 dfaa5c196b7acc602a00e94ebffb3977 316 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CWR44_RS05155 de73131d471a882ec33a8f9dde40d046 297 SUPERFAMILY SSF53850 93 275 1.09E-12 T 28-03-2018 CWR44_RS05155 de73131d471a882ec33a8f9dde40d046 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS05155 de73131d471a882ec33a8f9dde40d046 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS05155 de73131d471a882ec33a8f9dde40d046 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.5E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS05155 de73131d471a882ec33a8f9dde40d046 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.4E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CWR44_RS05155 de73131d471a882ec33a8f9dde40d046 297 Gene3D G3DSA:1.10.10.10 3 92 8.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS05155 de73131d471a882ec33a8f9dde40d046 297 Pfam PF03466 LysR substrate binding domain 91 274 6.5E-9 T 28-03-2018 IPR005119 LysR, substrate-binding CWR44_RS05155 de73131d471a882ec33a8f9dde40d046 297 Gene3D G3DSA:3.40.190.10 93 205 1.3E-9 T 28-03-2018 CWR44_RS05155 de73131d471a882ec33a8f9dde40d046 297 SUPERFAMILY SSF46785 3 89 9.98E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00245 0a05b18dbabe23afab52cbf82ec3bb9e 111 Gene3D G3DSA:1.10.10.10 1 111 9.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00245 0a05b18dbabe23afab52cbf82ec3bb9e 111 SUPERFAMILY SSF46785 4 102 3.14E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00245 0a05b18dbabe23afab52cbf82ec3bb9e 111 Pfam PF01638 HxlR-like helix-turn-helix 13 103 1.8E-16 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CWR44_RS05705 567e1c780f7c4017c97ff77ef9745f5f 358 Pfam PF01063 Amino-transferase class IV 67 308 3.1E-37 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR44_RS05705 567e1c780f7c4017c97ff77ef9745f5f 358 ProSitePatterns PS00770 Aminotransferases class-IV signature. 231 260 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR44_RS05705 567e1c780f7c4017c97ff77ef9745f5f 358 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 42 353 4.6E-123 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CWR44_RS05705 567e1c780f7c4017c97ff77ef9745f5f 358 SUPERFAMILY SSF56752 12 351 4.06E-115 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CWR44_RS05705 567e1c780f7c4017c97ff77ef9745f5f 358 PIRSF PIRSF006468 1 356 1.3E-128 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CWR44_RS05705 567e1c780f7c4017c97ff77ef9745f5f 358 Gene3D G3DSA:3.30.470.10 1 172 3.2E-61 T 28-03-2018 CWR44_RS05705 567e1c780f7c4017c97ff77ef9745f5f 358 Gene3D G3DSA:3.20.10.10 173 350 4.6E-53 T 28-03-2018 CWR44_RS04595 db3a181c20cf39bbf201a466b41f8e74 293 SUPERFAMILY SSF82861 33 117 2.22E-15 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CWR44_RS04595 db3a181c20cf39bbf201a466b41f8e74 293 Gene3D G3DSA:3.30.70.100 192 282 3.8E-6 T 28-03-2018 CWR44_RS04595 db3a181c20cf39bbf201a466b41f8e74 293 Gene3D G3DSA:2.30.30.60 134 188 4.2E-13 T 28-03-2018 CWR44_RS04595 db3a181c20cf39bbf201a466b41f8e74 293 SUPERFAMILY SSF82689 192 283 1.31E-6 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CWR44_RS04595 db3a181c20cf39bbf201a466b41f8e74 293 SUPERFAMILY SSF50182 119 187 2.39E-12 T 28-03-2018 IPR010920 LSM domain CWR44_RS04595 db3a181c20cf39bbf201a466b41f8e74 293 Pfam PF00924 Mechanosensitive ion channel 75 277 3.3E-39 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CWR44_RS08500 c152a86ff018150376fcd2a79a89bda3 247 SUPERFAMILY SSF81606 2 242 1.57E-61 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR44_RS08500 c152a86ff018150376fcd2a79a89bda3 247 SMART SM00332 2 240 1.1E-22 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR44_RS08500 c152a86ff018150376fcd2a79a89bda3 247 Gene3D G3DSA:3.60.40.10 2 242 2.3E-43 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR44_RS08500 c152a86ff018150376fcd2a79a89bda3 247 Pfam PF13672 Protein phosphatase 2C 14 219 5.1E-16 T 28-03-2018 CWR44_RS08500 c152a86ff018150376fcd2a79a89bda3 247 SMART SM00331 8 242 7.2E-32 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CWR44_RS05395 c74bb74f37b962fb736d0da82141650d 310 Gene3D G3DSA:3.40.50.1100 43 140 1.7E-40 T 28-03-2018 CWR44_RS05395 c74bb74f37b962fb736d0da82141650d 310 Gene3D G3DSA:3.40.50.1100 141 309 3.8E-58 T 28-03-2018 CWR44_RS05395 c74bb74f37b962fb736d0da82141650d 310 SUPERFAMILY SSF53686 5 306 1.44E-104 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR44_RS05395 c74bb74f37b962fb736d0da82141650d 310 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 35 53 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CWR44_RS05395 c74bb74f37b962fb736d0da82141650d 310 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 306 1.3E-133 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CWR44_RS05395 c74bb74f37b962fb736d0da82141650d 310 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 306 8.5E-141 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CWR44_RS05395 c74bb74f37b962fb736d0da82141650d 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 294 1.4E-72 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 Pfam PF16326 ABC transporter C-terminal domain 557 622 1.6E-13 T 28-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 SUPERFAMILY SSF52540 308 528 3.16E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 SUPERFAMILY SSF52540 5 94 3.45E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 SUPERFAMILY SSF52540 128 242 3.45E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 Pfam PF00005 ABC transporter 20 186 6.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 Pfam PF00005 ABC transporter 336 469 3.7E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 SMART SM00382 28 231 3.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 SMART SM00382 343 521 2.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 Gene3D G3DSA:3.40.50.300 286 552 3.8E-52 T 28-03-2018 CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 Gene3D G3DSA:3.40.50.300 2 285 8.7E-53 T 28-03-2018 CWR44_RS06625 65d8f08505f72b2bb8ec336e82e59a95 626 Pfam PF12848 ABC transporter 225 297 4.8E-12 T 28-03-2018 IPR032781 ABC-transporter extension domain CWR44_RS13095 e11b548c0ffc5f330edffe23fa02bb36 62 Pfam PF12669 Virus attachment protein p12 family 6 42 2.0E-9 T 28-03-2018 CWR44_RS13225 e11b548c0ffc5f330edffe23fa02bb36 62 Pfam PF12669 Virus attachment protein p12 family 6 42 2.0E-9 T 28-03-2018 CWR44_RS08930 fad6296e7413b40a728d7c4d14947809 80 SUPERFAMILY SSF50182 6 64 5.67E-20 T 28-03-2018 IPR010920 LSM domain CWR44_RS08930 fad6296e7413b40a728d7c4d14947809 80 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 64 2.4E-29 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CWR44_RS08930 fad6296e7413b40a728d7c4d14947809 80 Gene3D G3DSA:2.30.30.100 5 69 7.8E-28 T 28-03-2018 CWR44_RS08930 fad6296e7413b40a728d7c4d14947809 80 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 65 26.532 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CWR44_RS08930 fad6296e7413b40a728d7c4d14947809 80 Pfam PF17209 Hfq protein 7 69 1.8E-25 T 28-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CWR44_RS02530 cc7c93d4b52511d727c409a43f45fbbd 70 Gene3D G3DSA:1.10.150.260 1 68 3.9E-19 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS02530 cc7c93d4b52511d727c409a43f45fbbd 70 SUPERFAMILY SSF140652 1 67 2.62E-19 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS02530 cc7c93d4b52511d727c409a43f45fbbd 70 Pfam PF06855 YozE SAM-like fold 2 67 7.3E-18 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS08305 8311060957e2a0fb1cefcd569214f4ea 133 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 44 126 1.9E-21 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CWR44_RS08305 8311060957e2a0fb1cefcd569214f4ea 133 Pfam PF04977 Septum formation initiator 51 125 3.7E-10 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CWR44_RS08305 8311060957e2a0fb1cefcd569214f4ea 133 Hamap MF_00910 Cell division protein FtsL [ftsL]. 44 126 12.968 T 28-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CWR44_RS03620 b2099ad8f7fa405c250584545412fd9f 362 SUPERFAMILY SSF50891 245 358 6.07E-41 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS03620 b2099ad8f7fa405c250584545412fd9f 362 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 358 4.8E-138 T 28-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CWR44_RS03620 b2099ad8f7fa405c250584545412fd9f 362 Gene3D G3DSA:2.40.100.10 244 358 2.1E-43 T 28-03-2018 IPR029000 Cyclophilin-like domain CWR44_RS03620 b2099ad8f7fa405c250584545412fd9f 362 SUPERFAMILY SSF51445 1 241 1.58E-87 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWR44_RS03620 b2099ad8f7fa405c250584545412fd9f 362 Gene3D G3DSA:3.20.20.70 3 238 4.5E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS09665 28c31cb04682dc50b7f05aa2bc692fb7 353 Pfam PF03864 Phage major capsid protein E 33 332 2.5E-15 T 28-03-2018 IPR005564 Major capsid protein GpE GO:0019028 CWR44_RS09665 28c31cb04682dc50b7f05aa2bc692fb7 353 Gene3D G3DSA:3.90.1690.10 1 342 4.8E-41 T 28-03-2018 CWR44_RS11455 80204d176631e62f8862e8b0ec09f3de 155 Gene3D G3DSA:3.30.450.40 5 154 1.9E-22 T 28-03-2018 IPR029016 GAF domain-like CWR44_RS11455 80204d176631e62f8862e8b0ec09f3de 155 Pfam PF01590 GAF domain 70 152 9.5E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 CWR44_RS11455 80204d176631e62f8862e8b0ec09f3de 155 SUPERFAMILY SSF55781 7 149 6.54E-41 T 28-03-2018 IPR029016 GAF domain-like CWR44_RS11455 80204d176631e62f8862e8b0ec09f3de 155 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 92 109 - T 28-03-2018 IPR000614 Free Met sulfoxide reductase conserved site CWR44_RS05605 44fdb74c3504888a4b3601638048ee5a 140 Gene3D G3DSA:3.30.1550.10 3 71 2.1E-36 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CWR44_RS05605 44fdb74c3504888a4b3601638048ee5a 140 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 4.8E-31 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CWR44_RS05605 44fdb74c3504888a4b3601638048ee5a 140 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 3.8E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR44_RS05605 44fdb74c3504888a4b3601638048ee5a 140 SUPERFAMILY SSF46906 67 139 5.1E-28 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR44_RS05605 44fdb74c3504888a4b3601638048ee5a 140 SUPERFAMILY SSF54747 3 72 3.14E-30 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CWR44_RS05605 44fdb74c3504888a4b3601638048ee5a 140 SMART SM00649 9 140 4.4E-88 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CWR44_RS05605 44fdb74c3504888a4b3601638048ee5a 140 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 1.0E-16 T 28-03-2018 CWR44_RS05605 44fdb74c3504888a4b3601638048ee5a 140 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 139 2.6E-65 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS05605 44fdb74c3504888a4b3601638048ee5a 140 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 140 31.159 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CWR44_RS05605 44fdb74c3504888a4b3601638048ee5a 140 Gene3D G3DSA:1.10.10.250 72 140 4.4E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CWR44_RS08025 8a19801c0855c7200b127e9b41c3ea53 270 Gene3D G3DSA:1.10.3720.10 7 266 8.0E-34 T 28-03-2018 CWR44_RS08025 8a19801c0855c7200b127e9b41c3ea53 270 SUPERFAMILY SSF161098 9 246 7.06E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS08025 8a19801c0855c7200b127e9b41c3ea53 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 260 1.1E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS07150 ade6fb13b31a3988c23009a884448cd0 413 Gene3D G3DSA:3.90.1150.10 286 411 2.3E-45 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS07150 ade6fb13b31a3988c23009a884448cd0 413 SUPERFAMILY SSF53383 7 405 6.59E-130 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS07150 ade6fb13b31a3988c23009a884448cd0 413 Gene3D G3DSA:3.40.640.10 37 285 6.8E-63 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS07150 ade6fb13b31a3988c23009a884448cd0 413 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 10 410 7.7E-187 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWR44_RS07150 ade6fb13b31a3988c23009a884448cd0 413 Pfam PF00266 Aminotransferase class-V 29 398 3.7E-161 T 28-03-2018 IPR000192 Aminotransferase class V domain CWR44_RS07150 ade6fb13b31a3988c23009a884448cd0 413 PIRSF PIRSF005572 25 411 1.4E-51 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CWR44_RS04545 d008280626ccf6cbfefe7f48ee855eeb 128 SUPERFAMILY SSF54593 3 127 2.95E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS04545 d008280626ccf6cbfefe7f48ee855eeb 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 125 2.7E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWR44_RS04545 d008280626ccf6cbfefe7f48ee855eeb 128 Gene3D G3DSA:3.10.180.10 5 128 6.6E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS12480 16a65f007f8370074dfe4cb4fc10ae47 460 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 209 216 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS12480 16a65f007f8370074dfe4cb4fc10ae47 460 Gene3D G3DSA:3.40.309.10 229 410 1.6E-66 T 28-03-2018 CWR44_RS12480 16a65f007f8370074dfe4cb4fc10ae47 460 Gene3D G3DSA:3.40.605.10 2 228 2.2E-63 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS12480 16a65f007f8370074dfe4cb4fc10ae47 460 SUPERFAMILY SSF53720 4 446 2.23E-120 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR44_RS12480 16a65f007f8370074dfe4cb4fc10ae47 460 Pfam PF00171 Aldehyde dehydrogenase family 4 429 6.3E-92 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS12480 16a65f007f8370074dfe4cb4fc10ae47 460 PIRSF PIRSF036492 2 460 1.1E-186 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CWR44_RS12480 16a65f007f8370074dfe4cb4fc10ae47 460 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 237 248 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS11410 fca2b697b9948f8212c48474fec5c331 165 PIRSF PIRSF006276 1 146 3.4E-23 T 28-03-2018 IPR006015 Universal stress protein A CWR44_RS11410 fca2b697b9948f8212c48474fec5c331 165 PRINTS PR01438 Universal stress protein signature 103 115 1.4E-18 T 28-03-2018 IPR006015 Universal stress protein A CWR44_RS11410 fca2b697b9948f8212c48474fec5c331 165 PRINTS PR01438 Universal stress protein signature 121 143 1.4E-18 T 28-03-2018 IPR006015 Universal stress protein A CWR44_RS11410 fca2b697b9948f8212c48474fec5c331 165 PRINTS PR01438 Universal stress protein signature 4 22 1.4E-18 T 28-03-2018 IPR006015 Universal stress protein A CWR44_RS11410 fca2b697b9948f8212c48474fec5c331 165 Pfam PF00582 Universal stress protein family 4 143 1.7E-35 T 28-03-2018 IPR006016 UspA GO:0006950 CWR44_RS11410 fca2b697b9948f8212c48474fec5c331 165 SUPERFAMILY SSF52402 4 149 3.18E-36 T 28-03-2018 CWR44_RS11410 fca2b697b9948f8212c48474fec5c331 165 Gene3D G3DSA:3.40.50.620 2 154 1.6E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS01065 fb27df359877a843b922ec6ae292e8e1 262 Pfam PF00459 Inositol monophosphatase family 36 241 4.7E-37 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS01065 fb27df359877a843b922ec6ae292e8e1 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 7.9E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS01065 fb27df359877a843b922ec6ae292e8e1 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 204 228 7.9E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS01065 fb27df359877a843b922ec6ae292e8e1 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 7.9E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS01065 fb27df359877a843b922ec6ae292e8e1 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 7.9E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS01065 fb27df359877a843b922ec6ae292e8e1 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 7.9E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS01065 fb27df359877a843b922ec6ae292e8e1 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 173 194 7.9E-24 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CWR44_RS01065 fb27df359877a843b922ec6ae292e8e1 262 SUPERFAMILY SSF56655 17 255 2.75E-58 T 28-03-2018 CWR44_RS01065 fb27df359877a843b922ec6ae292e8e1 262 Gene3D G3DSA:3.40.190.80 146 261 1.4E-21 T 28-03-2018 CWR44_RS01065 fb27df359877a843b922ec6ae292e8e1 262 Gene3D G3DSA:3.30.540.10 1 144 3.3E-31 T 28-03-2018 CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 28-03-2018 IPR018215 ClpP, Ser active site CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 191 1.1E-104 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 Gene3D G3DSA:3.90.226.10 2 194 7.3E-47 T 28-03-2018 CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 6.4E-55 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 6.4E-55 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 6.4E-55 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 6.4E-55 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 6.4E-55 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 28-03-2018 IPR033135 ClpP, histidine active site CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 SUPERFAMILY SSF52096 11 193 4.97E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 Pfam PF00574 Clp protease 13 192 4.8E-89 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CWR44_RS06890 d76cc3a77e582b8a2c0d7ebce764a523 195 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.295 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CWR44_RS08360 5e958b75479beecfdaabff6135920ee4 275 Gene3D G3DSA:3.10.290.10 195 249 6.5E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS08360 5e958b75479beecfdaabff6135920ee4 275 Pfam PF01479 S4 domain 199 243 2.4E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS08360 5e958b75479beecfdaabff6135920ee4 275 SMART SM00363 198 255 2.9E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CWR44_RS08360 5e958b75479beecfdaabff6135920ee4 275 SUPERFAMILY SSF55174 195 268 2.22E-30 T 28-03-2018 CWR44_RS08360 5e958b75479beecfdaabff6135920ee4 275 SUPERFAMILY SSF55174 54 144 2.22E-30 T 28-03-2018 CWR44_RS07070 b6e8dd52d46abf84fa0d0c5cecb4dfa1 140 SUPERFAMILY SSF82784 1 137 5.37E-34 T 28-03-2018 IPR003718 OsmC/Ohr family CWR44_RS07070 b6e8dd52d46abf84fa0d0c5cecb4dfa1 140 Pfam PF02566 OsmC-like protein 37 134 9.0E-18 T 28-03-2018 IPR003718 OsmC/Ohr family CWR44_RS07070 b6e8dd52d46abf84fa0d0c5cecb4dfa1 140 Gene3D G3DSA:2.20.25.10 1 41 8.4E-10 T 28-03-2018 CWR44_RS07070 b6e8dd52d46abf84fa0d0c5cecb4dfa1 140 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 136 8.5E-46 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CWR44_RS07070 b6e8dd52d46abf84fa0d0c5cecb4dfa1 140 Gene3D G3DSA:3.30.300.20 42 140 2.7E-23 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWR44_RS07905 e98c4537f977adf16b2bedc00e532bbd 390 Gene3D G3DSA:3.40.50.150 175 388 1.7E-26 T 28-03-2018 CWR44_RS07905 e98c4537f977adf16b2bedc00e532bbd 390 SUPERFAMILY SSF88697 1 70 9.69E-18 T 28-03-2018 IPR015947 PUA-like domain CWR44_RS07905 e98c4537f977adf16b2bedc00e532bbd 390 Gene3D G3DSA:3.30.750.80 70 174 6.5E-27 T 28-03-2018 CWR44_RS07905 e98c4537f977adf16b2bedc00e532bbd 390 Gene3D G3DSA:2.30.130.10 3 65 6.3E-15 T 28-03-2018 IPR002478 PUA domain GO:0003723 CWR44_RS07905 e98c4537f977adf16b2bedc00e532bbd 390 SUPERFAMILY SSF53335 77 385 1.8E-61 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS07905 e98c4537f977adf16b2bedc00e532bbd 390 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 150 356 8.9E-24 T 28-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CWR44_RS05135 dc84927eb017e80679e294b2404402d5 129 Pfam PF00293 NUDIX domain 6 111 7.0E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR44_RS05135 dc84927eb017e80679e294b2404402d5 129 Gene3D G3DSA:3.90.79.10 3 113 4.0E-17 T 28-03-2018 CWR44_RS05135 dc84927eb017e80679e294b2404402d5 129 SUPERFAMILY SSF55811 4 127 1.02E-20 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR44_RS02960 0f76cadc6eef690fc5e71df5a787e9b9 267 Pfam PF11611 Domain of unknown function (DUF4352) 1 114 3.2E-10 T 28-03-2018 IPR029051 Domain of unknown function DUF4352 CWR44_RS02960 0f76cadc6eef690fc5e71df5a787e9b9 267 Gene3D G3DSA:2.60.40.1240 1 168 1.8E-14 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CWR44_RS04470 a6175981f3c6e085d5f74d33d8efea44 240 Pfam PF02527 rRNA small subunit methyltransferase G 22 193 8.9E-56 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWR44_RS04470 a6175981f3c6e085d5f74d33d8efea44 240 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 15 214 28.428 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWR44_RS04470 a6175981f3c6e085d5f74d33d8efea44 240 SUPERFAMILY SSF53335 5 237 8.05E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS04470 a6175981f3c6e085d5f74d33d8efea44 240 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 199 2.9E-50 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWR44_RS04470 a6175981f3c6e085d5f74d33d8efea44 240 Gene3D G3DSA:3.40.50.150 4 238 1.1E-42 T 28-03-2018 CWR44_RS04470 a6175981f3c6e085d5f74d33d8efea44 240 PIRSF PIRSF003078 3 220 3.0E-57 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CWR44_RS02460 b4ac85b15026a547e2bf7421fe2eb03a 160 Gene3D G3DSA:3.40.50.300 1 18 7.4E-4 T 28-03-2018 CWR44_RS02460 b4ac85b15026a547e2bf7421fe2eb03a 160 SUPERFAMILY SSF52540 3 130 3.18E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS02460 b4ac85b15026a547e2bf7421fe2eb03a 160 Gene3D G3DSA:3.40.50.300 19 112 1.7E-12 T 28-03-2018 CWR44_RS02460 b4ac85b15026a547e2bf7421fe2eb03a 160 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 5 61 1.1E-4 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CWR44_RS02940 4a44684352f5e827dbe42dc4ee3effa4 119 Pfam PF13564 DoxX-like family 18 97 1.5E-6 T 28-03-2018 IPR032808 DoxX family CWR44_RS06105 ee4f1d43abc8c7e3e007a97187d90c98 269 SUPERFAMILY SSF53474 3 260 7.63E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS06105 ee4f1d43abc8c7e3e007a97187d90c98 269 Pfam PF00561 alpha/beta hydrolase fold 22 133 8.0E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS06105 ee4f1d43abc8c7e3e007a97187d90c98 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 5.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS06105 ee4f1d43abc8c7e3e007a97187d90c98 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 218 5.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS06105 ee4f1d43abc8c7e3e007a97187d90c98 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 5.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS06105 ee4f1d43abc8c7e3e007a97187d90c98 269 Gene3D G3DSA:3.40.50.1820 2 260 4.9E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS02785 73932e5c2ec9a6609c655045eead4a94 380 SMART SM00854 32 279 7.4E-87 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CWR44_RS02785 73932e5c2ec9a6609c655045eead4a94 380 Gene3D G3DSA:3.60.21.10 23 371 1.4E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS02785 73932e5c2ec9a6609c655045eead4a94 380 SUPERFAMILY SSF56300 34 280 9.01E-39 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS02785 73932e5c2ec9a6609c655045eead4a94 380 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 33 279 3.8E-66 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CWR44_RS08115 a389566a9f2f58f0e0beb4d3f38e28b1 145 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 114 8.5E-16 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CWR44_RS08115 a389566a9f2f58f0e0beb4d3f38e28b1 145 Gene3D G3DSA:1.20.1500.10 8 117 1.1E-23 T 28-03-2018 IPR023378 YheA/YmcA-like domain CWR44_RS08115 a389566a9f2f58f0e0beb4d3f38e28b1 145 SUPERFAMILY SSF158622 3 125 1.19E-32 T 28-03-2018 IPR023378 YheA/YmcA-like domain CWR44_RS03375 768e23e9e0ac6783fe4f6c9e2c71099f 136 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.6E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS03375 768e23e9e0ac6783fe4f6c9e2c71099f 136 Gene3D G3DSA:1.10.1660.10 56 136 1.2E-6 T 28-03-2018 CWR44_RS03375 768e23e9e0ac6783fe4f6c9e2c71099f 136 SUPERFAMILY SSF46955 1 115 2.05E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain CWR44_RS03375 768e23e9e0ac6783fe4f6c9e2c71099f 136 Gene3D G3DSA:1.10.1660.10 1 55 8.5E-18 T 28-03-2018 CWR44_RS03375 768e23e9e0ac6783fe4f6c9e2c71099f 136 SMART SM00422 1 69 2.0E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS01660 8eab3c1850cfdc5cfabc9ba2e0a8eaf5 272 SUPERFAMILY SSF56300 1 120 4.43E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS01660 8eab3c1850cfdc5cfabc9ba2e0a8eaf5 272 SUPERFAMILY SSF56300 152 252 4.43E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS01660 8eab3c1850cfdc5cfabc9ba2e0a8eaf5 272 TIGRFAM TIGR03729 acc_ester: putative phosphoesterase 2 247 5.5E-74 T 28-03-2018 IPR022302 Phosphoesterase, putative CWR44_RS01660 8eab3c1850cfdc5cfabc9ba2e0a8eaf5 272 Gene3D G3DSA:3.60.21.10 1 266 1.4E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS01660 8eab3c1850cfdc5cfabc9ba2e0a8eaf5 272 Pfam PF00149 Calcineurin-like phosphoesterase 1 228 2.1E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR44_RS01420 fbe0721dbf41ae05b17da01ade448464 204 Pfam PF14278 Transcriptional regulator C-terminal region 93 167 1.1E-15 T 28-03-2018 CWR44_RS01420 fbe0721dbf41ae05b17da01ade448464 204 Gene3D G3DSA:1.10.10.60 47 143 8.5E-5 T 28-03-2018 CWR44_RS01420 fbe0721dbf41ae05b17da01ade448464 204 SUPERFAMILY SSF46689 4 69 8.21E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS01420 fbe0721dbf41ae05b17da01ade448464 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 57 5.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS01420 fbe0721dbf41ae05b17da01ade448464 204 Gene3D G3DSA:1.10.10.60 2 46 5.1E-11 T 28-03-2018 CWR44_RS08850 dd6cfa97f553a90e45429581d53d2c19 264 Gene3D G3DSA:3.60.21.10 1 264 7.2E-49 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS08850 dd6cfa97f553a90e45429581d53d2c19 264 SUPERFAMILY SSF56300 1 255 3.8E-83 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS08850 dd6cfa97f553a90e45429581d53d2c19 264 PIRSF PIRSF004789 1 263 1.9E-104 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CWR44_RS08850 dd6cfa97f553a90e45429581d53d2c19 264 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 262 1.6E-105 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CWR44_RS08850 dd6cfa97f553a90e45429581d53d2c19 264 Pfam PF13277 YmdB-like protein 4 254 6.3E-107 T 28-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CWR44_RS02440 1ce716f91ba56bcd91e3da6d4b13dea3 209 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 172 202 0.0023 T 28-03-2018 CWR44_RS02440 1ce716f91ba56bcd91e3da6d4b13dea3 209 Pfam PF00746 LPXTG cell wall anchor motif 166 207 1.8E-4 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 Pfam PF00206 Lyase 7 286 2.7E-74 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 427 7.8E-174 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 428 1.1E-25 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 SUPERFAMILY SSF48557 3 428 4.56E-140 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 5.5E-26 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 5.5E-26 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 5.5E-26 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 5.5E-26 T 28-03-2018 IPR000362 Fumarate lyase family CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 Gene3D G3DSA:1.10.40.30 349 428 3.4E-28 T 28-03-2018 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 9.6E-9 T 28-03-2018 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 9.6E-9 T 28-03-2018 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 9.6E-9 T 28-03-2018 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 9.6E-9 T 28-03-2018 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 SMART SM00998 349 429 5.5E-40 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 Gene3D G3DSA:1.20.200.10 93 348 4.2E-80 T 28-03-2018 CWR44_RS12425 1f683f54ddee0c517c2a759233e59fed 431 Gene3D G3DSA:1.10.275.10 2 92 1.6E-24 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CWR44_RS01575 b1d2331a66e4101b07db344e311ea9c9 243 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS01575 b1d2331a66e4101b07db344e311ea9c9 243 PIRSF PIRSF039085 1 242 2.9E-107 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CWR44_RS01575 b1d2331a66e4101b07db344e311ea9c9 243 SUPERFAMILY SSF52540 1 235 2.42E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS01575 b1d2331a66e4101b07db344e311ea9c9 243 Pfam PF00005 ABC transporter 18 166 1.5E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS01575 b1d2331a66e4101b07db344e311ea9c9 243 Gene3D G3DSA:3.40.50.300 1 243 5.1E-75 T 28-03-2018 CWR44_RS01575 b1d2331a66e4101b07db344e311ea9c9 243 SMART SM00382 26 214 3.4E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 SUPERFAMILY SSF100950 76 234 4.71E-28 T 28-03-2018 CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 Gene3D G3DSA:3.40.50.1360 68 239 2.3E-28 T 28-03-2018 CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 8.4E-24 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 Gene3D G3DSA:1.10.10.10 1 67 1.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 SUPERFAMILY SSF46785 5 63 5.28E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.9E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.9E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 Pfam PF00455 DeoR C terminal sensor domain 76 234 5.6E-45 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 SMART SM01134 74 235 1.5E-56 T 28-03-2018 CWR44_RS00620 d352112e752c18799cb7db73d241a46b 251 SMART SM00420 6 58 3.0E-25 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CWR44_RS04185 de60877295fd377b2f8a41962691db0f 109 Gene3D G3DSA:1.10.460.10 14 105 3.7E-27 T 28-03-2018 CWR44_RS04185 de60877295fd377b2f8a41962691db0f 109 SUPERFAMILY SSF56712 8 98 8.89E-25 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CWR44_RS04185 de60877295fd377b2f8a41962691db0f 109 SMART SM00436 1 80 1.5E-13 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CWR44_RS04185 de60877295fd377b2f8a41962691db0f 109 Pfam PF01131 DNA topoisomerase 15 101 3.9E-23 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CWR44_RS02945 92aeda22b0bf85ebec0c7b115d437154 279 Pfam PF13460 NAD(P)H-binding 7 188 1.7E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02945 92aeda22b0bf85ebec0c7b115d437154 279 SUPERFAMILY SSF51735 2 251 1.28E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02945 92aeda22b0bf85ebec0c7b115d437154 279 Gene3D G3DSA:3.40.50.720 1 271 1.7E-22 T 28-03-2018 CWR44_RS01890 feabb9d358e25a3fd17b1dff773f10d7 288 SUPERFAMILY SSF53448 3 268 1.73E-69 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS01890 feabb9d358e25a3fd17b1dff773f10d7 288 Pfam PF00483 Nucleotidyl transferase 6 258 5.4E-35 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CWR44_RS01890 feabb9d358e25a3fd17b1dff773f10d7 288 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 2.1E-119 T 28-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CWR44_RS01890 feabb9d358e25a3fd17b1dff773f10d7 288 Gene3D G3DSA:3.90.550.10 2 277 2.3E-62 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS11425 23deb7ef88a8023c268ab7bf7c593de5 315 SUPERFAMILY SSF53335 23 296 9.3E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS11425 23deb7ef88a8023c268ab7bf7c593de5 315 Gene3D G3DSA:3.40.50.150 72 312 1.4E-26 T 28-03-2018 CWR44_RS11425 23deb7ef88a8023c268ab7bf7c593de5 315 Pfam PF02384 N-6 DNA Methylase 98 283 2.3E-8 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CWR44_RS11425 23deb7ef88a8023c268ab7bf7c593de5 315 PIRSF PIRSF026567 3 313 5.7E-107 T 28-03-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 SUPERFAMILY SSF52540 160 344 4.35E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 SUPERFAMILY SSF82051 1 157 8.37E-55 T 28-03-2018 IPR006169 GTP1/OBG domain CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 Pfam PF01926 50S ribosome-binding GTPase 160 283 3.1E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 Gene3D G3DSA:2.70.210.12 1 155 1.8E-57 T 28-03-2018 IPR006169 GTP1/OBG domain CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 Pfam PF01018 GTP1/OBG 3 157 2.2E-59 T 28-03-2018 IPR006169 GTP1/OBG domain CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 PIRSF PIRSF002401 1 378 1.4E-139 T 28-03-2018 IPR035101 GTP-binding protein, Obg-type CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 1.9E-139 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 Gene3D G3DSA:3.40.50.300 158 335 1.7E-32 T 28-03-2018 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 Pfam PF09269 Domain of unknown function (DUF1967) 360 428 6.1E-25 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 Hamap MF_01454 GTPase Obg [obg]. 1 329 46.529 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 SUPERFAMILY SSF102741 358 430 4.84E-23 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CWR44_RS11120 28bca6e05533461a550e281b58223c82 430 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 360 429 1.3E-26 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 1472 1529 0.03 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 1395 1452 0.0047 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 1011 1068 0.053 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 934 991 0.033 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 1318 1374 0.041 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 1780 1842 0.01 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 1088 1149 0.1 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 1549 1606 0.026 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 1703 1758 0.0036 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 1626 1688 0.085 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 2011 2077 0.043 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.5.420 780 832 0.005 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF00746 LPXTG cell wall anchor motif 2117 2153 3.9E-5 T 28-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 4 37 6.7E-9 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 TIGRFAM TIGR04263 SasC_Mrp_aggreg: SasC/Mrp/FmtB intercellular aggregation domain 170 565 3.1E-138 T 28-03-2018 IPR026359 SasC/Mrp/FmtB intercellular aggregation domain CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.1270.90 555 637 8.2E-7 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF04650 YSIRK type signal peptide 5 26 3.8E-8 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:2.60.40.1170 394 500 2.8E-7 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2119 2152 6.9E-7 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Gene3D G3DSA:1.20.1270.90 833 898 0.61 T 28-03-2018 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1391 1465 3.3E-18 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 930 1006 8.7E-20 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1776 1851 7.1E-20 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1930 2004 1.5E-11 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1699 1774 1.1E-18 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 623 697 1.3E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1007 1082 1.6E-19 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1545 1620 4.5E-20 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 853 928 3.9E-14 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1315 1388 1.3E-15 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1622 1697 1.9E-19 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1161 1236 7.7E-18 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 699 773 5.5E-15 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1853 1929 1.1E-17 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1084 1158 4.5E-19 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1238 1312 1.0E-18 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 2007 2082 1.7E-10 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 776 850 1.8E-17 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11665 a0b8ecc2167a21b6c32b13eb0910eab5 2156 Pfam PF07564 Domain of Unknown Function (DUF1542) 1468 1543 1.3E-17 T 28-03-2018 IPR011439 Domain of unknown function DUF1542 CWR44_RS11135 c6eef8941d1ca825b15c59a720a1107c 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 26.352 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11135 c6eef8941d1ca825b15c59a720a1107c 102 SUPERFAMILY SSF141091 1 100 2.09E-38 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11135 c6eef8941d1ca825b15c59a720a1107c 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 7.6E-41 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS11135 c6eef8941d1ca825b15c59a720a1107c 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 1.3E-39 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS10255 9879979aad18db7e595adf77094aced0 400 SUPERFAMILY SSF81301 6 138 1.14E-42 T 28-03-2018 CWR44_RS10255 9879979aad18db7e595adf77094aced0 400 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 170 226 1.2E-10 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CWR44_RS10255 9879979aad18db7e595adf77094aced0 400 Pfam PF01743 Poly A polymerase head domain 23 142 1.7E-35 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CWR44_RS10255 9879979aad18db7e595adf77094aced0 400 Gene3D G3DSA:1.10.3090.10 143 398 7.5E-36 T 28-03-2018 CWR44_RS10255 9879979aad18db7e595adf77094aced0 400 SUPERFAMILY SSF81891 141 397 5.89E-50 T 28-03-2018 CWR44_RS10255 9879979aad18db7e595adf77094aced0 400 Hamap MF_01263 CCA-adding enzyme [cca]. 3 398 38.287 T 28-03-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 CWR44_RS10255 9879979aad18db7e595adf77094aced0 400 Gene3D G3DSA:3.30.460.10 2 142 3.3E-46 T 28-03-2018 CWR44_RS10255 9879979aad18db7e595adf77094aced0 400 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 246 394 1.0E-25 T 28-03-2018 IPR032810 CCA-adding enzyme, C-terminal CWR44_RS13245 48c716ca9b59b95b9224b5815d260969 186 SUPERFAMILY SSF46689 2 63 1.64E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS13245 48c716ca9b59b95b9224b5815d260969 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS13245 48c716ca9b59b95b9224b5815d260969 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS13245 48c716ca9b59b95b9224b5815d260969 186 Gene3D G3DSA:1.10.10.60 38 73 2.2E-8 T 28-03-2018 CWR44_RS13245 48c716ca9b59b95b9224b5815d260969 186 SUPERFAMILY SSF48498 71 184 1.42E-38 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CWR44_RS13245 48c716ca9b59b95b9224b5815d260969 186 Gene3D G3DSA:1.10.10.60 1 37 1.9E-11 T 28-03-2018 CWR44_RS13245 48c716ca9b59b95b9224b5815d260969 186 ProSitePatterns PS01081 TetR-type HTH domain signature. 17 47 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CWR44_RS13245 48c716ca9b59b95b9224b5815d260969 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 51 2.2E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS13245 48c716ca9b59b95b9224b5815d260969 186 Pfam PF08360 QacR-like protein, C-terminal region 55 186 8.5E-61 T 28-03-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 CWR44_RS09245 ae94d8f1542614100eaeb774236f32ef 119 Pfam PF15542 Bacterial toxin 50 11 111 2.8E-24 T 28-03-2018 IPR029100 Bacterial toxin 50 CWR44_RS05075 1f2027963a2d2f0234ad6760df8a07d6 228 Pfam PF01569 PAP2 superfamily 102 212 2.4E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR44_RS05075 1f2027963a2d2f0234ad6760df8a07d6 228 SUPERFAMILY SSF48317 16 216 1.31E-26 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR44_RS05075 1f2027963a2d2f0234ad6760df8a07d6 228 SMART SM00014 99 211 3.2E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR44_RS05075 1f2027963a2d2f0234ad6760df8a07d6 228 Gene3D G3DSA:1.20.144.10 22 215 1.1E-18 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 SUPERFAMILY SSF51735 102 283 1.93E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 Pfam PF01842 ACT domain 462 518 1.8E-6 T 28-03-2018 IPR002912 ACT domain CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 SUPERFAMILY SSF52283 24 130 4.73E-36 T 28-03-2018 CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 Gene3D G3DSA:3.30.1330.90 320 450 2.2E-27 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 Gene3D G3DSA:3.40.50.720 114 285 1.5E-58 T 28-03-2018 CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 4 525 4.1E-209 T 28-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 SUPERFAMILY SSF55021 445 524 2.71E-15 T 28-03-2018 CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 282 1.5E-63 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 314 2.7E-35 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 Gene3D G3DSA:3.40.50.720 2 113 6.2E-34 T 28-03-2018 CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 Gene3D G3DSA:3.30.70.260 451 524 2.3E-12 T 28-03-2018 CWR44_RS11485 5002f6886603aedbd1b6211d11917741 532 SUPERFAMILY SSF143548 322 451 1.41E-27 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CWR44_RS10545 6fd94cd34b36eb4c45f7b3b620f485f0 128 SUPERFAMILY SSF48013 2 127 4.45E-39 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR44_RS10545 6fd94cd34b36eb4c45f7b3b620f485f0 128 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 128 20.753 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CWR44_RS10545 6fd94cd34b36eb4c45f7b3b620f485f0 128 Gene3D G3DSA:1.10.940.10 1 128 7.1E-39 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR44_RS10545 6fd94cd34b36eb4c45f7b3b620f485f0 128 Pfam PF01029 NusB family 5 127 8.5E-37 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CWR44_RS10545 6fd94cd34b36eb4c45f7b3b620f485f0 128 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 3 127 2.1E-41 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CWR44_RS09485 ca81f3750bc9c4f1fdbcfdd62afe50cd 422 Gene3D G3DSA:3.40.50.300 142 417 2.6E-40 T 28-03-2018 CWR44_RS09485 ca81f3750bc9c4f1fdbcfdd62afe50cd 422 SUPERFAMILY SSF52540 144 249 4.64E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS09485 ca81f3750bc9c4f1fdbcfdd62afe50cd 422 SUPERFAMILY SSF52540 276 398 4.64E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS09485 ca81f3750bc9c4f1fdbcfdd62afe50cd 422 Pfam PF03796 DnaB-like helicase C terminal domain 159 413 4.8E-66 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CWR44_RS01135 ad986bb75430fbdcef3a11c70b5a90e4 253 Gene3D G3DSA:1.10.10.10 3 72 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01135 ad986bb75430fbdcef3a11c70b5a90e4 253 SUPERFAMILY SSF53697 82 247 9.57E-21 T 28-03-2018 CWR44_RS01135 ad986bb75430fbdcef3a11c70b5a90e4 253 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 72 1.3E-15 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR44_RS01135 ad986bb75430fbdcef3a11c70b5a90e4 253 SUPERFAMILY SSF46689 5 73 5.91E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS01135 ad986bb75430fbdcef3a11c70b5a90e4 253 Pfam PF01380 SIS domain 110 219 7.8E-16 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR44_RS01135 ad986bb75430fbdcef3a11c70b5a90e4 253 Gene3D G3DSA:3.40.50.10490 73 251 7.6E-20 T 28-03-2018 CWR44_RS03760 26d50ee8263438a72503fbf50e00e1d9 220 SUPERFAMILY SSF52540 1 219 8.31E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03760 26d50ee8263438a72503fbf50e00e1d9 220 Pfam PF00005 ABC transporter 22 168 4.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS03760 26d50ee8263438a72503fbf50e00e1d9 220 Gene3D G3DSA:3.40.50.300 1 220 5.6E-60 T 28-03-2018 CWR44_RS03760 26d50ee8263438a72503fbf50e00e1d9 220 SMART SM00382 30 216 1.7E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03760 26d50ee8263438a72503fbf50e00e1d9 220 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS04070 baffe0204b85aacf529c8a47978d361d 231 SMART SM00862 148 227 9.7E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS04070 baffe0204b85aacf529c8a47978d361d 231 SUPERFAMILY SSF52172 3 184 1.57E-38 T 28-03-2018 IPR011006 CheY-like superfamily CWR44_RS04070 baffe0204b85aacf529c8a47978d361d 231 Pfam PF00072 Response regulator receiver domain 6 114 1.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS04070 baffe0204b85aacf529c8a47978d361d 231 SMART SM00448 3 113 2.9E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CWR44_RS04070 baffe0204b85aacf529c8a47978d361d 231 Gene3D G3DSA:1.10.10.10 123 231 2.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04070 baffe0204b85aacf529c8a47978d361d 231 Gene3D G3DSA:3.40.50.2300 1 122 2.7E-33 T 28-03-2018 CWR44_RS04070 baffe0204b85aacf529c8a47978d361d 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 227 5.9E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CWR44_RS04250 2558b8c61196704e0b1a9ef63390afe4 369 Gene3D G3DSA:3.30.70.370 124 366 7.2E-14 T 28-03-2018 CWR44_RS04250 2558b8c61196704e0b1a9ef63390afe4 369 SUPERFAMILY SSF56672 18 358 4.34E-42 T 28-03-2018 CWR44_RS04250 2558b8c61196704e0b1a9ef63390afe4 369 Pfam PF00476 DNA polymerase family A 31 351 2.0E-11 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CWR44_RS12385 310c25805f7d915d1e096261353d5f90 485 ProSitePatterns PS00571 Amidases signature. 152 183 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CWR44_RS12385 310c25805f7d915d1e096261353d5f90 485 Pfam PF01425 Amidase 24 465 9.5E-160 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWR44_RS12385 310c25805f7d915d1e096261353d5f90 485 SUPERFAMILY SSF75304 1 480 4.45E-160 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWR44_RS12385 310c25805f7d915d1e096261353d5f90 485 Gene3D G3DSA:3.90.1300.10 1 485 3.6E-170 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWR44_RS12385 310c25805f7d915d1e096261353d5f90 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 5.2E-200 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWR44_RS12385 310c25805f7d915d1e096261353d5f90 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 92.678 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CWR44_RS11945 9f775d15b7d33f62b93c5c629efac040 398 Gene3D G3DSA:3.60.21.10 1 82 6.0E-16 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS11945 9f775d15b7d33f62b93c5c629efac040 398 Gene3D G3DSA:3.60.21.10 83 249 1.1E-19 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS11945 9f775d15b7d33f62b93c5c629efac040 398 SUPERFAMILY SSF56300 2 291 2.53E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS11945 9f775d15b7d33f62b93c5c629efac040 398 PIRSF PIRSF033091 1 398 3.5E-143 T 28-03-2018 IPR014576 Predicted phosphoesterase, YhaO type CWR44_RS11945 9f775d15b7d33f62b93c5c629efac040 398 Pfam PF00149 Calcineurin-like phosphoesterase 3 199 1.8E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR44_RS05270 5ce0a7ba367bea6d7ad3ec7fd4be1887 82 Gene3D G3DSA:3.40.1440.10 1 82 2.6E-9 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR44_RS05270 5ce0a7ba367bea6d7ad3ec7fd4be1887 82 Pfam PF01541 GIY-YIG catalytic domain 3 74 1.8E-19 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR44_RS05270 5ce0a7ba367bea6d7ad3ec7fd4be1887 82 SMART SM00465 3 80 0.0082 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR44_RS05270 5ce0a7ba367bea6d7ad3ec7fd4be1887 82 SUPERFAMILY SSF82771 3 73 3.27E-16 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR44_RS03720 0077678eee77ac9af626a168d894671c 287 Pfam PF13365 Trypsin-like peptidase domain 99 248 7.7E-11 T 28-03-2018 CWR44_RS03720 0077678eee77ac9af626a168d894671c 287 SUPERFAMILY SSF50494 66 259 3.68E-24 T 28-03-2018 IPR009003 Peptidase S1, PA clan CWR44_RS03720 0077678eee77ac9af626a168d894671c 287 Gene3D G3DSA:2.40.10.10 174 275 2.0E-5 T 28-03-2018 CWR44_RS03720 0077678eee77ac9af626a168d894671c 287 Gene3D G3DSA:2.40.10.10 89 173 2.1E-7 T 28-03-2018 CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 Pfam PF00717 Peptidase S24-like 126 193 8.5E-17 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 133 144 2.9E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 162 174 2.9E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 122 132 2.9E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 SUPERFAMILY SSF51306 83 205 6.1E-36 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 TIGRFAM TIGR00498 lexA: repressor LexA 1 206 1.2E-75 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 SUPERFAMILY SSF46785 3 70 2.93E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 Gene3D G3DSA:1.10.10.10 2 68 2.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 Pfam PF01726 LexA DNA binding domain 1 65 6.6E-28 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 Hamap MF_00015 LexA repressor [lexA]. 3 207 35.558 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CWR44_RS09390 0396de349cf3f60b6f1cfa267a1ef1b1 207 Gene3D G3DSA:2.10.109.10 89 207 2.5E-26 T 28-03-2018 CWR44_RS01440 522574e12f0b59c4e255bd6e2a71d915 701 Gene3D G3DSA:1.10.10.60 202 253 3.6E-9 T 28-03-2018 CWR44_RS01440 522574e12f0b59c4e255bd6e2a71d915 701 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 200 242 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CWR44_RS01440 522574e12f0b59c4e255bd6e2a71d915 701 SUPERFAMILY SSF46689 200 248 1.34E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS01440 522574e12f0b59c4e255bd6e2a71d915 701 SMART SM00342 163 246 9.1E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS01440 522574e12f0b59c4e255bd6e2a71d915 701 Gene3D G3DSA:2.60.40.1500 563 701 5.2E-10 T 28-03-2018 CWR44_RS01440 522574e12f0b59c4e255bd6e2a71d915 701 Pfam PF12833 Helix-turn-helix domain 169 247 9.4E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CWR44_RS01440 522574e12f0b59c4e255bd6e2a71d915 701 Gene3D G3DSA:2.60.120.10 12 201 1.1E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWR44_RS05955 5d8842b139fd455b4580d8731e6f0c55 113 Pfam PF07293 Protein of unknown function (DUF1450) 7 73 1.7E-8 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CWR44_RS05955 5d8842b139fd455b4580d8731e6f0c55 113 Hamap MF_01863 UPF0741 protein . 1 74 31.123 T 28-03-2018 IPR020880 Protein of unknown function UPF0741 CWR44_RS07640 810bef9b255831bd8f4890beef594800 58 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 3 57 4.7E-27 T 28-03-2018 IPR018690 Protein of unknown function DUF2187 CWR44_RS07220 b797518b88f5874b3c419848d0fd769d 49 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 15 49 4.6E-15 T 28-03-2018 IPR021008 Protein of unknown function DUF3687 CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 68 3.3E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 SMART SM00345 9 68 6.7E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 SMART SM00866 90 231 5.9E-11 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 SUPERFAMILY SSF46785 5 78 5.66E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.4E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.4E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 SUPERFAMILY SSF64288 75 234 6.44E-31 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 Gene3D G3DSA:3.40.1410.10 74 241 9.2E-21 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 Pfam PF07702 UTRA domain 91 231 2.5E-20 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 5 238 3.1E-71 T 28-03-2018 IPR012770 Trehalose operon transcriptional repressor CWR44_RS05185 227b76dde56cdbf33b0255602a68931c 241 Gene3D G3DSA:1.10.10.10 2 69 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00970 b80030fa366dc1a1cec5f1c9e7852f0e 114 SUPERFAMILY SSF46785 9 113 5.27E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00970 b80030fa366dc1a1cec5f1c9e7852f0e 114 Pfam PF02082 Transcriptional regulator 35 82 9.0E-5 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CWR44_RS00970 b80030fa366dc1a1cec5f1c9e7852f0e 114 TIGRFAM TIGR01889 Staph_reg_Sar: staphylococcal accessory regulator family 8 114 4.4E-30 T 28-03-2018 IPR010166 Transcriptional regulator SarA/Rot GO:0006355 CWR44_RS00970 b80030fa366dc1a1cec5f1c9e7852f0e 114 Gene3D G3DSA:1.10.10.10 3 114 1.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS09890 17059ae00229f53df37f4d7dc3feee70 106 SUPERFAMILY SSF54427 18 105 4.38E-10 T 28-03-2018 IPR032710 NTF2-like domain CWR44_RS09890 17059ae00229f53df37f4d7dc3feee70 106 Gene3D G3DSA:3.10.450.50 4 104 1.9E-10 T 28-03-2018 CWR44_RS05730 0497bc90512c91feec68a01dc1c28f60 149 Pfam PF00583 Acetyltransferase (GNAT) family 31 114 6.5E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS05730 0497bc90512c91feec68a01dc1c28f60 149 Gene3D G3DSA:3.40.630.30 7 149 2.2E-25 T 28-03-2018 CWR44_RS05730 0497bc90512c91feec68a01dc1c28f60 149 SUPERFAMILY SSF55729 13 147 3.95E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS01780 3483004c4c6c873711ca9ea4f06929a1 76 Gene3D G3DSA:1.20.58.340 1 65 2.3E-4 T 28-03-2018 CWR44_RS01780 3483004c4c6c873711ca9ea4f06929a1 76 SUPERFAMILY SSF144083 11 64 1.15E-5 T 28-03-2018 CWR44_RS03590 18061a5c7034a8c268a803b7c0ae54e1 134 PIRSF PIRSF021328 1 134 8.0E-42 T 28-03-2018 IPR016787 Uncharacterised conserved protein UCP021328 CWR44_RS03590 18061a5c7034a8c268a803b7c0ae54e1 134 Pfam PF11208 Protein of unknown function (DUF2992) 3 134 5.9E-37 T 28-03-2018 IPR016787 Uncharacterised conserved protein UCP021328 CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 SMART SM00382 147 332 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 Gene3D G3DSA:1.10.1140.10 355 464 3.1E-43 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 Gene3D G3DSA:2.40.10.170 1 78 4.7E-29 T 28-03-2018 CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 5.5E-254 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 348 2.1E-67 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 SUPERFAMILY SSF50615 1 78 2.16E-25 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 SUPERFAMILY SSF52540 81 354 4.36E-89 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 Gene3D G3DSA:3.40.50.300 80 354 1.3E-90 T 28-03-2018 CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 57.218 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 SUPERFAMILY SSF47917 351 466 6.28E-51 T 28-03-2018 CWR44_RS00145 bb691a18b27ba6754bc5bdc3088329d6 470 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 77 1.0E-21 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CWR44_RS05905 63a789d2bae5d63c46fb1ebdcb31f6e2 492 Pfam PF13520 Amino acid permease 25 450 1.1E-40 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS05905 63a789d2bae5d63c46fb1ebdcb31f6e2 492 PIRSF PIRSF006060 1 477 8.6E-74 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS03565 9ca3a8703967fad98143f1c3e41fecd6 175 SUPERFAMILY SSF109854 2 171 1.68E-43 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CWR44_RS03565 9ca3a8703967fad98143f1c3e41fecd6 175 Pfam PF12867 DinB superfamily 33 163 4.5E-12 T 28-03-2018 IPR024775 DinB-like domain CWR44_RS03565 9ca3a8703967fad98143f1c3e41fecd6 175 Gene3D G3DSA:1.20.120.450 1 173 9.3E-29 T 28-03-2018 CWR44_RS03120 275d6380004a107673159271674e6534 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 129 146 5.5E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR44_RS03120 275d6380004a107673159271674e6534 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 156 169 5.5E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR44_RS03120 275d6380004a107673159271674e6534 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 72 83 5.5E-10 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CWR44_RS03120 275d6380004a107673159271674e6534 383 SUPERFAMILY SSF69189 313 379 1.26E-24 T 28-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CWR44_RS03120 275d6380004a107673159271674e6534 383 Gene3D G3DSA:2.30.140.20 312 376 1.3E-21 T 28-03-2018 IPR015294 Penicillin-binding protein 4, C-terminal domain CWR44_RS03120 275d6380004a107673159271674e6534 383 Pfam PF09211 Domain of unknown function (DUF1958) 314 376 9.1E-18 T 28-03-2018 IPR015294 Penicillin-binding protein 4, C-terminal domain CWR44_RS03120 275d6380004a107673159271674e6534 383 Gene3D G3DSA:3.40.710.10 26 308 1.3E-37 T 28-03-2018 CWR44_RS03120 275d6380004a107673159271674e6534 383 SUPERFAMILY SSF56601 44 311 1.02E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR44_RS03120 275d6380004a107673159271674e6534 383 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 50 286 3.8E-49 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CWR44_RS05900 ad1587a6df0eadc67f1052f9b9f63a41 123 Pfam PF04241 Protein of unknown function (DUF423) 19 104 9.8E-32 T 28-03-2018 IPR006696 Protein of unknown function DUF423 CWR44_RS11025 47b0a58d7de1e7fcd9d598f113478390 334 SUPERFAMILY SSF51679 4 327 4.32E-78 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CWR44_RS11025 47b0a58d7de1e7fcd9d598f113478390 334 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 7 327 2.0E-126 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CWR44_RS11025 47b0a58d7de1e7fcd9d598f113478390 334 Pfam PF00296 Luciferase-like monooxygenase 19 298 1.4E-33 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CWR44_RS11025 47b0a58d7de1e7fcd9d598f113478390 334 Gene3D G3DSA:3.20.20.30 10 331 1.3E-63 T 28-03-2018 CWR44_RS04430 ecb22c17484e3fda12199f90cdd408e5 371 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CWR44_RS04430 ecb22c17484e3fda12199f90cdd408e5 371 ProSitePatterns PS00618 RecF protein signature 2. 313 331 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CWR44_RS04430 ecb22c17484e3fda12199f90cdd408e5 371 Gene3D G3DSA:3.40.50.300 1 371 2.1E-33 T 28-03-2018 CWR44_RS04430 ecb22c17484e3fda12199f90cdd408e5 371 SUPERFAMILY SSF52540 1 217 2.66E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04430 ecb22c17484e3fda12199f90cdd408e5 371 SUPERFAMILY SSF52540 245 353 2.66E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04430 ecb22c17484e3fda12199f90cdd408e5 371 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 348 4.9E-17 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CWR44_RS04430 ecb22c17484e3fda12199f90cdd408e5 371 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 371 102.618 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CWR44_RS04430 ecb22c17484e3fda12199f90cdd408e5 371 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 368 1.2E-138 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CWR44_RS00310 135158a67c86b9514d365bd060938faa 395 Pfam PF01676 Metalloenzyme superfamily 6 379 6.2E-42 T 28-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CWR44_RS00310 135158a67c86b9514d365bd060938faa 395 Hamap MF_00740 Phosphopentomutase [deoB]. 5 388 52.523 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWR44_RS00310 135158a67c86b9514d365bd060938faa 395 Gene3D G3DSA:3.40.720.10 270 387 1.4E-9 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CWR44_RS00310 135158a67c86b9514d365bd060938faa 395 TIGRFAM TIGR01696 deoB: phosphopentomutase 7 386 1.4E-213 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWR44_RS00310 135158a67c86b9514d365bd060938faa 395 SUPERFAMILY SSF143856 101 217 1.06E-50 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWR44_RS00310 135158a67c86b9514d365bd060938faa 395 Gene3D G3DSA:3.30.70.1250 100 217 2.3E-55 T 28-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWR44_RS00310 135158a67c86b9514d365bd060938faa 395 SUPERFAMILY SSF53649 218 390 3.14E-73 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR44_RS00310 135158a67c86b9514d365bd060938faa 395 SUPERFAMILY SSF53649 5 101 3.14E-73 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CWR44_RS00310 135158a67c86b9514d365bd060938faa 395 PIRSF PIRSF001491 4 392 6.5E-162 T 28-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CWR44_RS02190 24b26589f94a0824be996e38d3044b9d 144 Pfam PF05257 CHAP domain 39 120 2.3E-14 T 28-03-2018 IPR007921 CHAP domain CWR44_RS02190 24b26589f94a0824be996e38d3044b9d 144 SUPERFAMILY SSF54001 23 135 8.83E-23 T 28-03-2018 CWR44_RS10505 1db81268ad5687f565141c33d1dc3f15 327 Gene3D G3DSA:3.40.50.920 195 326 1.6E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR44_RS10505 1db81268ad5687f565141c33d1dc3f15 327 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 4.8E-47 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR44_RS10505 1db81268ad5687f565141c33d1dc3f15 327 SUPERFAMILY SSF52518 1 204 4.18E-71 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS10505 1db81268ad5687f565141c33d1dc3f15 327 SUPERFAMILY SSF52922 189 325 2.49E-37 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR44_RS10505 1db81268ad5687f565141c33d1dc3f15 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 1.0E-37 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CWR44_RS10505 1db81268ad5687f565141c33d1dc3f15 327 SMART SM00861 4 179 7.0E-67 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR44_RS10505 1db81268ad5687f565141c33d1dc3f15 327 Gene3D G3DSA:3.40.50.970 1 194 5.1E-69 T 28-03-2018 CWR44_RS04375 0e963f29d657c3e647f4482d1993d454 466 Pfam PF03796 DnaB-like helicase C terminal domain 185 457 5.3E-115 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CWR44_RS04375 0e963f29d657c3e647f4482d1993d454 466 Gene3D G3DSA:1.10.860.10 2 151 3.6E-45 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CWR44_RS04375 0e963f29d657c3e647f4482d1993d454 466 SUPERFAMILY SSF48024 8 119 2.22E-35 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWR44_RS04375 0e963f29d657c3e647f4482d1993d454 466 Pfam PF00772 DnaB-like helicase N terminal domain 10 110 8.2E-34 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CWR44_RS04375 0e963f29d657c3e647f4482d1993d454 466 SUPERFAMILY SSF52540 183 450 5.34E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS04375 0e963f29d657c3e647f4482d1993d454 466 Gene3D G3DSA:3.40.50.300 167 466 2.8E-76 T 28-03-2018 CWR44_RS04375 0e963f29d657c3e647f4482d1993d454 466 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 458 3.4E-177 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CWR44_RS03935 ee4e43271d85ab34ed42626180858919 214 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 210 22.68 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CWR44_RS03935 ee4e43271d85ab34ed42626180858919 214 SUPERFAMILY SSF52218 3 210 2.21E-33 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS03935 ee4e43271d85ab34ed42626180858919 214 Pfam PF02525 Flavodoxin-like fold 3 204 3.3E-30 T 28-03-2018 IPR003680 Flavodoxin-like fold CWR44_RS03935 ee4e43271d85ab34ed42626180858919 214 Gene3D G3DSA:3.40.50.360 3 213 2.2E-21 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS02030 c93ecbf146da2da5efc9d1783ebf816d 302 SMART SM00062 49 280 8.0E-7 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CWR44_RS02030 c93ecbf146da2da5efc9d1783ebf816d 302 Gene3D G3DSA:3.40.190.10 139 286 3.4E-34 T 28-03-2018 CWR44_RS02030 c93ecbf146da2da5efc9d1783ebf816d 302 Gene3D G3DSA:3.40.190.10 32 138 1.1E-11 T 28-03-2018 CWR44_RS02030 c93ecbf146da2da5efc9d1783ebf816d 302 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 41 290 4.6E-68 T 28-03-2018 CWR44_RS02030 c93ecbf146da2da5efc9d1783ebf816d 302 SUPERFAMILY SSF53850 36 300 1.22E-46 T 28-03-2018 CWR44_RS02030 c93ecbf146da2da5efc9d1783ebf816d 302 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 1 263 5.9E-75 T 28-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 CWR44_RS01285 de38962da7ab209f4c95a3058c4798a7 152 SMART SM00347 29 131 2.4E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS01285 de38962da7ab209f4c95a3058c4798a7 152 Pfam PF01047 MarR family 36 89 5.7E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS01285 de38962da7ab209f4c95a3058c4798a7 152 SUPERFAMILY SSF46785 16 147 1.07E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01285 de38962da7ab209f4c95a3058c4798a7 152 Gene3D G3DSA:1.10.10.10 1 152 4.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02835 31d5047fdc5b4d9389eacbc391813756 253 Gene3D G3DSA:3.40.50.1820 1 253 1.2E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS02835 31d5047fdc5b4d9389eacbc391813756 253 Pfam PF00756 Putative esterase 35 244 1.3E-11 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CWR44_RS02835 31d5047fdc5b4d9389eacbc391813756 253 SUPERFAMILY SSF53474 2 251 1.94E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS07080 50be303632606eaf117b52534184a481 179 Pfam PF00881 Nitroreductase family 7 156 2.0E-23 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR44_RS07080 50be303632606eaf117b52534184a481 179 SUPERFAMILY SSF55469 2 173 2.09E-33 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR44_RS07080 50be303632606eaf117b52534184a481 179 Gene3D G3DSA:3.40.109.10 1 179 3.0E-28 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR44_RS10405 1665fcf8de7ccde5c70657dea0fed0ef 243 Hamap MF_01805 Segregation and condensation protein A [scpA]. 2 238 24.001 T 28-03-2018 IPR003768 Segregation and condensation protein A CWR44_RS10405 1665fcf8de7ccde5c70657dea0fed0ef 243 Pfam PF02616 Segregation and condensation protein ScpA 19 234 4.6E-37 T 28-03-2018 IPR003768 Segregation and condensation protein A CWR44_RS10405 1665fcf8de7ccde5c70657dea0fed0ef 243 Gene3D G3DSA:1.10.10.580 168 235 9.0E-10 T 28-03-2018 CWR44_RS03495 a9bc04b5e5d2d2b66abad7899d848f13 170 Pfam PF03729 Short repeat of unknown function (DUF308) 14 86 3.0E-9 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CWR44_RS03495 a9bc04b5e5d2d2b66abad7899d848f13 170 Pfam PF03729 Short repeat of unknown function (DUF308) 129 169 0.0055 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CWR44_RS03495 a9bc04b5e5d2d2b66abad7899d848f13 170 Pfam PF03729 Short repeat of unknown function (DUF308) 72 131 1.3E-5 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CWR44_RS08570 85949656a22f5265b422b676639f6e16 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CWR44_RS08570 85949656a22f5265b422b676639f6e16 77 Hamap MF_01217 Acyl carrier protein [acpP]. 2 76 22.709 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWR44_RS08570 85949656a22f5265b422b676639f6e16 77 Pfam PF00550 Phosphopantetheine attachment site 5 72 1.2E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWR44_RS08570 85949656a22f5265b422b676639f6e16 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 4 74 5.1E-33 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWR44_RS08570 85949656a22f5265b422b676639f6e16 77 SUPERFAMILY SSF47336 4 75 1.83E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CWR44_RS08570 85949656a22f5265b422b676639f6e16 77 Gene3D G3DSA:1.10.1200.10 1 77 4.4E-26 T 28-03-2018 CWR44_RS08570 85949656a22f5265b422b676639f6e16 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 34 74 2.0E-11 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CWR44_RS04550 7c977e6a0bf66e9a9aee1536a491049f 155 Gene3D G3DSA:1.20.120.450 4 152 1.4E-8 T 28-03-2018 CWR44_RS04550 7c977e6a0bf66e9a9aee1536a491049f 155 SUPERFAMILY SSF109854 27 150 2.2E-8 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CWR44_RS06430 d3381f5d72fc89fdc09459cf782e3be6 181 Pfam PF13302 Acetyltransferase (GNAT) domain 9 153 2.7E-25 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS06430 d3381f5d72fc89fdc09459cf782e3be6 181 Gene3D G3DSA:3.40.630.30 1 175 6.8E-20 T 28-03-2018 CWR44_RS06430 d3381f5d72fc89fdc09459cf782e3be6 181 SUPERFAMILY SSF55729 2 158 5.41E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS06210 282897996f41199fdddad7406bdf596a 254 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 65 239 5.1E-54 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CWR44_RS06210 282897996f41199fdddad7406bdf596a 254 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 10 248 57.953 T 28-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 CWR44_RS06210 282897996f41199fdddad7406bdf596a 254 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 69 233 2.1E-53 T 28-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CWR44_RS06350 9f3cc717b0f69a8bf7aa5d095b41c407 334 Pfam PF01384 Phosphate transporter family 22 323 2.0E-91 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CWR44_RS07605 c5cc8b176d79341111c31779e138d5bc 84 ProDom PD060056 YUEH 1 77 0.007 T 28-03-2018 IPR020260 Uncharacterised protein family YueH CWR44_RS07605 c5cc8b176d79341111c31779e138d5bc 84 Pfam PF14166 YueH-like protein 9 76 2.2E-19 T 28-03-2018 IPR020260 Uncharacterised protein family YueH CWR44_RS07890 424a9b5d356147f4b15e3f9fe765d1c0 191 Pfam PF09819 ABC-type cobalt transport system, permease component 9 125 6.8E-31 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CWR44_RS07890 424a9b5d356147f4b15e3f9fe765d1c0 191 PIRSF PIRSF037394 1 191 6.8E-60 T 28-03-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted CWR44_RS06435 85db0ca05c2a5bd8997d12f1b897a246 188 Gene3D G3DSA:3.40.50.450 1 178 1.2E-53 T 28-03-2018 CWR44_RS06435 85db0ca05c2a5bd8997d12f1b897a246 188 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 173 2.0E-58 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CWR44_RS06435 85db0ca05c2a5bd8997d12f1b897a246 188 SUPERFAMILY SSF102405 1 179 2.75E-57 T 28-03-2018 CWR44_RS06435 85db0ca05c2a5bd8997d12f1b897a246 188 Pfam PF03641 Possible lysine decarboxylase 46 173 9.7E-42 T 28-03-2018 IPR031100 LOG family CWR44_RS02845 6c99c9a2c923faaa362c79383c6a5879 476 PIRSF PIRSF006060 1 476 9.5E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS02845 6c99c9a2c923faaa362c79383c6a5879 476 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 1 475 2.3E-176 T 28-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 CWR44_RS02845 6c99c9a2c923faaa362c79383c6a5879 476 Pfam PF13520 Amino acid permease 12 415 3.3E-74 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS02845 6c99c9a2c923faaa362c79383c6a5879 476 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 8 475 5.1E-194 T 28-03-2018 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 CWR44_RS00725 05818dd1011cc7294560c7bfbaa1b7bd 132 Gene3D G3DSA:3.30.1370.30 1 67 1.4E-26 T 28-03-2018 CWR44_RS00725 05818dd1011cc7294560c7bfbaa1b7bd 132 Gene3D G3DSA:3.30.1490.10 76 131 5.6E-23 T 28-03-2018 CWR44_RS00725 05818dd1011cc7294560c7bfbaa1b7bd 132 Pfam PF00410 Ribosomal protein S8 5 132 6.0E-54 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00725 05818dd1011cc7294560c7bfbaa1b7bd 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.933 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00725 05818dd1011cc7294560c7bfbaa1b7bd 132 SUPERFAMILY SSF56047 3 132 2.49E-48 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00725 05818dd1011cc7294560c7bfbaa1b7bd 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS08100 d027f29c5745dae67114b789608ae66e 303 Pfam PF01040 UbiA prenyltransferase family 32 284 2.2E-57 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CWR44_RS08100 d027f29c5745dae67114b789608ae66e 303 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 15 299 16.813 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CWR44_RS08100 d027f29c5745dae67114b789608ae66e 303 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 17 296 1.8E-94 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CWR44_RS10810 646741f99204191b9da40d54328548c2 253 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 8 250 5.9E-59 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS10810 646741f99204191b9da40d54328548c2 253 SUPERFAMILY SSF75217 76 250 4.07E-53 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CWR44_RS10810 646741f99204191b9da40d54328548c2 253 Pfam PF04452 RNA methyltransferase 21 247 1.6E-70 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS10810 646741f99204191b9da40d54328548c2 253 PIRSF PIRSF015601 3 252 6.6E-61 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CWR44_RS10810 646741f99204191b9da40d54328548c2 253 Gene3D G3DSA:3.40.1280.10 2 252 1.5E-68 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CWR44_RS10810 646741f99204191b9da40d54328548c2 253 SUPERFAMILY SSF88697 5 73 3.23E-13 T 28-03-2018 IPR015947 PUA-like domain CWR44_RS00270 ac32117ce12867b2dca2cb71050f530f 172 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 13 93 1.2E-31 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CWR44_RS00270 ac32117ce12867b2dca2cb71050f530f 172 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 171 15.039 T 28-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CWR44_RS00270 ac32117ce12867b2dca2cb71050f530f 172 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 81 1.4E-10 T 28-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 Gene3D G3DSA:3.40.50.300 472 1008 6.6E-47 T 28-03-2018 CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1041 1213 1.8E-7 T 28-03-2018 CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 Gene3D G3DSA:3.90.320.10 1009 1221 9.6E-37 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 10 1223 17.945 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 SUPERFAMILY SSF52980 1000 1218 6.97E-38 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 Gene3D G3DSA:3.40.50.300 6 471 3.9E-52 T 28-03-2018 CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 12 1221 0.0 T 28-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 Pfam PF00580 UvrD/REP helicase N-terminal domain 13 458 2.0E-77 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 Pfam PF13361 UvrD-like helicase C-terminal domain 469 873 3.7E-32 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 SUPERFAMILY SSF52540 852 877 3.04E-107 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 SUPERFAMILY SSF52540 343 810 3.04E-107 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07405 ebd84e9c13c66c24c0d272971ff6facc 1225 SUPERFAMILY SSF52540 5 200 3.04E-107 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS08955 46ef380d131e24ce3b5ba633b1122fbd 446 SUPERFAMILY SSF55931 108 443 1.47E-123 T 28-03-2018 CWR44_RS08955 46ef380d131e24ce3b5ba633b1122fbd 446 Gene3D G3DSA:3.10.20.70 4 106 4.3E-37 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWR44_RS08955 46ef380d131e24ce3b5ba633b1122fbd 446 ProSitePatterns PS00180 Glutamine synthetase signature 1. 54 72 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CWR44_RS08955 46ef380d131e24ce3b5ba633b1122fbd 446 SUPERFAMILY SSF54368 8 106 1.1E-34 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWR44_RS08955 46ef380d131e24ce3b5ba633b1122fbd 446 Pfam PF00120 Glutamine synthetase, catalytic domain 108 442 5.5E-135 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWR44_RS08955 46ef380d131e24ce3b5ba633b1122fbd 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 236 251 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CWR44_RS08955 46ef380d131e24ce3b5ba633b1122fbd 446 SMART SM01230 107 356 1.2E-133 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWR44_RS08955 46ef380d131e24ce3b5ba633b1122fbd 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 19 100 1.1E-31 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWR44_RS08955 46ef380d131e24ce3b5ba633b1122fbd 446 Gene3D G3DSA:3.30.590.10 107 446 2.0E-123 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CWR44_RS08955 46ef380d131e24ce3b5ba633b1122fbd 446 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 10 443 3.3E-171 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CWR44_RS07230 de084df8d55cfffcc83ec781580c9aab 404 PIRSF PIRSF500216 1 404 2.4E-162 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB CWR44_RS07230 de084df8d55cfffcc83ec781580c9aab 404 PIRSF PIRSF016636 2 403 1.0E-77 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CWR44_RS07230 de084df8d55cfffcc83ec781580c9aab 404 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 73 376 2.1E-19 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CWR44_RS07230 de084df8d55cfffcc83ec781580c9aab 404 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 3 403 8.6E-152 T 28-03-2018 IPR024024 D-alanyl transfer protein DltB CWR44_RS04965 2be44d47acbb80957a011b1e1b21ebd2 101 Pfam PF07342 Protein of unknown function (DUF1474) 1 101 7.5E-34 T 28-03-2018 IPR009942 Protein of unknown function DUF1474 CWR44_RS07765 5f23bbddf9a70a5f8b3b8845a909017f 418 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 86 233 2.7E-40 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR44_RS07765 5f23bbddf9a70a5f8b3b8845a909017f 418 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 86 233 3.5E-33 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR44_RS06030 8819fa0789c12842878ae03a6c0bab2d 36 Pfam PF10855 Protein of unknown function (DUF2648) 5 36 1.4E-10 T 28-03-2018 IPR022561 Protein of unknown function DUF2648 CWR44_RS06030 8819fa0789c12842878ae03a6c0bab2d 36 ProDom PD610536 SE2200 SAV2627.1 SA2420.1 MW2548 4 36 2.0E-4 T 28-03-2018 IPR022561 Protein of unknown function DUF2648 CWR44_RS12235 f7b4934364e38806df4409478681fd97 104 Gene3D G3DSA:1.10.287.880 2 51 9.7E-22 T 28-03-2018 CWR44_RS12235 f7b4934364e38806df4409478681fd97 104 SUPERFAMILY SSF101697 2 103 2.22E-40 T 28-03-2018 IPR014938 Protein of unknown function DUF1811 CWR44_RS12235 f7b4934364e38806df4409478681fd97 104 Pfam PF08838 Protein of unknown function (DUF1811) 4 103 3.2E-39 T 28-03-2018 IPR014938 Protein of unknown function DUF1811 CWR44_RS12235 f7b4934364e38806df4409478681fd97 104 Gene3D G3DSA:2.30.30.340 52 104 2.7E-17 T 28-03-2018 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 119 133 2.1E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 2.1E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 2.1E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 2.1E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 2.1E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 2.1E-58 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 Gene3D G3DSA:3.20.20.70 1 324 1.7E-148 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 SMART SM01004 1 322 6.2E-223 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 PIRSF PIRSF001415 1 324 3.3E-150 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 SUPERFAMILY SSF51569 3 323 4.1E-139 T 28-03-2018 CWR44_RS11205 359ec9707ffca4fd76cb33765214f179 324 Pfam PF00490 Delta-aminolevulinic acid dehydratase 4 319 1.9E-146 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CWR44_RS05140 703d4620992dc4e4ebe9127e8e9a9226 154 SUPERFAMILY SSF55729 1 147 2.09E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS05140 703d4620992dc4e4ebe9127e8e9a9226 154 Gene3D G3DSA:3.40.630.30 1 153 4.2E-14 T 28-03-2018 CWR44_RS05140 703d4620992dc4e4ebe9127e8e9a9226 154 Pfam PF00583 Acetyltransferase (GNAT) family 36 131 9.3E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS10685 ff817d2c4a88809230c6c0890f40eed8 681 Gene3D G3DSA:3.40.710.10 320 681 1.5E-70 T 28-03-2018 CWR44_RS10685 ff817d2c4a88809230c6c0890f40eed8 681 Gene3D G3DSA:3.90.1310.10 34 319 1.3E-38 T 28-03-2018 CWR44_RS10685 ff817d2c4a88809230c6c0890f40eed8 681 SUPERFAMILY SSF56519 62 123 6.93E-37 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR44_RS10685 ff817d2c4a88809230c6c0890f40eed8 681 SUPERFAMILY SSF56519 188 319 6.93E-37 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR44_RS10685 ff817d2c4a88809230c6c0890f40eed8 681 SUPERFAMILY SSF56601 320 677 1.03E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR44_RS10685 ff817d2c4a88809230c6c0890f40eed8 681 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 656 8.4E-60 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR44_RS10685 ff817d2c4a88809230c6c0890f40eed8 681 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 303 2.8E-41 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR44_RS08290 f1748634b17c9b51d855d32a2ed03a3b 537 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 537 29.733 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC CWR44_RS08290 f1748634b17c9b51d855d32a2ed03a3b 537 PIRSF PIRSF012535 1 537 2.9E-199 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC CWR44_RS08290 f1748634b17c9b51d855d32a2ed03a3b 537 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 11 535 6.6E-172 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC CWR44_RS08290 f1748634b17c9b51d855d32a2ed03a3b 537 Pfam PF10079 Bacillithiol biosynthesis BshC 1 530 8.4E-153 T 28-03-2018 IPR011199 Bacillithiol biosynthesis BshC CWR44_RS07470 eb127db2ae638dfc1c967d8f36a9c15f 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 302 3.4E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS07470 eb127db2ae638dfc1c967d8f36a9c15f 308 Gene3D G3DSA:1.10.3720.10 1 291 6.4E-41 T 28-03-2018 CWR44_RS07470 eb127db2ae638dfc1c967d8f36a9c15f 308 SUPERFAMILY SSF161098 87 285 2.18E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS10715 17e14946f974374537d19fb22eaddea6 448 Gene3D G3DSA:3.40.50.300 215 448 4.6E-44 T 28-03-2018 CWR44_RS10715 17e14946f974374537d19fb22eaddea6 448 SUPERFAMILY SSF52540 72 359 2.0E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS10715 17e14946f974374537d19fb22eaddea6 448 SMART SM00487 23 221 1.6E-45 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CWR44_RS10715 17e14946f974374537d19fb22eaddea6 448 Pfam PF00271 Helicase conserved C-terminal domain 232 338 2.0E-26 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS10715 17e14946f974374537d19fb22eaddea6 448 SMART SM00490 257 338 1.0E-28 T 28-03-2018 IPR001650 Helicase, C-terminal CWR44_RS10715 17e14946f974374537d19fb22eaddea6 448 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 4 437 46.02 T 28-03-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 CWR44_RS10715 17e14946f974374537d19fb22eaddea6 448 Pfam PF00270 DEAD/DEAH box helicase 28 192 2.1E-37 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CWR44_RS10715 17e14946f974374537d19fb22eaddea6 448 Gene3D G3DSA:3.40.50.300 1 214 1.7E-45 T 28-03-2018 CWR44_RS09670 67dd7a5edf8baff0b9a270de07e1bbe2 98 Gene3D G3DSA:1.10.720.30 38 98 3.5E-5 T 28-03-2018 IPR003034 SAP domain CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 PRINTS PR01270 Histone deacetylase superfamily signature 251 261 2.4E-14 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 PRINTS PR01270 Histone deacetylase superfamily signature 165 180 2.4E-14 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 PRINTS PR01270 Histone deacetylase superfamily signature 132 155 2.4E-14 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 Pfam PF00850 Histone deacetylase domain 24 320 7.1E-69 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 109 122 7.7E-41 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 336 352 7.7E-41 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 353 372 7.7E-41 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 18 38 7.7E-41 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 276 292 7.7E-41 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 88 102 7.7E-41 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 PRINTS PR01272 Acetoin utilisation ACUC protein signature 315 334 7.7E-41 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 SUPERFAMILY SSF52768 6 371 3.36E-97 T 28-03-2018 CWR44_RS11545 3975835fd11709a5cf58baa285aefee7 385 Gene3D G3DSA:3.40.800.20 4 382 3.3E-85 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CWR44_RS10850 5436099e5b33ce6058f8d70546dce0af 83 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 79 2.0E-18 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS10850 5436099e5b33ce6058f8d70546dce0af 83 Pfam PF01649 Ribosomal protein S20 2 80 7.2E-20 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS10850 5436099e5b33ce6058f8d70546dce0af 83 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 83 11.779 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS10850 5436099e5b33ce6058f8d70546dce0af 83 SUPERFAMILY SSF46992 3 81 1.96E-20 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS10850 5436099e5b33ce6058f8d70546dce0af 83 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 78 1.0E-9 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS10850 5436099e5b33ce6058f8d70546dce0af 83 Gene3D G3DSA:1.20.58.110 1 83 5.9E-20 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS01355 61777b8d4e1c8d67be8cff506a63a898 248 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 19 46 7.4E-29 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CWR44_RS01355 61777b8d4e1c8d67be8cff506a63a898 248 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 93 111 7.4E-29 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CWR44_RS01355 61777b8d4e1c8d67be8cff506a63a898 248 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 163 191 7.4E-29 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CWR44_RS01355 61777b8d4e1c8d67be8cff506a63a898 248 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 111 137 7.4E-29 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CWR44_RS01355 61777b8d4e1c8d67be8cff506a63a898 248 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 20 235 3.5E-46 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CWR44_RS01355 61777b8d4e1c8d67be8cff506a63a898 248 Pfam PF00902 Sec-independent protein translocase protein (TatC) 23 230 2.3E-45 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CWR44_RS01355 61777b8d4e1c8d67be8cff506a63a898 248 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 11 247 15.734 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CWR44_RS08870 66adfb8dccec543f14f0bfadea77c96c 98 Gene3D G3DSA:3.30.70.930 1 96 4.9E-20 T 28-03-2018 IPR029756 MTH1187/YkoF-like CWR44_RS08870 66adfb8dccec543f14f0bfadea77c96c 98 SUPERFAMILY SSF89957 4 95 1.31E-21 T 28-03-2018 IPR029756 MTH1187/YkoF-like CWR44_RS08870 66adfb8dccec543f14f0bfadea77c96c 98 Pfam PF01910 Thiamine-binding protein 6 79 1.5E-16 T 28-03-2018 IPR002767 Thiamine-binding protein CWR44_RS03415 728819b7cff8198cd8c44b1602d096a3 357 Gene3D G3DSA:3.40.50.150 1 136 1.2E-12 T 28-03-2018 CWR44_RS03415 728819b7cff8198cd8c44b1602d096a3 357 SUPERFAMILY SSF53335 2 138 3.63E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS03415 728819b7cff8198cd8c44b1602d096a3 357 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 6 12 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWR44_RS03415 728819b7cff8198cd8c44b1602d096a3 357 Pfam PF07669 Eco57I restriction-modification methylase 1 107 4.1E-31 T 28-03-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 CWR44_RS03110 777d73883fc40cb10d151e5927ac2c62 591 Gene3D G3DSA:3.40.50.720 27 528 4.5E-8 T 28-03-2018 CWR44_RS03110 777d73883fc40cb10d151e5927ac2c62 591 Pfam PF06100 MCRA family 23 520 6.5E-218 T 28-03-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 CWR44_RS03110 777d73883fc40cb10d151e5927ac2c62 591 SUPERFAMILY SSF51905 28 256 2.45E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03810 663a3c548c2ce3daa0d0dc05ad270aef 286 SUPERFAMILY SSF52151 9 220 1.31E-21 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CWR44_RS03810 663a3c548c2ce3daa0d0dc05ad270aef 286 Pfam PF01734 Patatin-like phospholipase 11 199 2.6E-13 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CWR44_RS03810 663a3c548c2ce3daa0d0dc05ad270aef 286 Gene3D G3DSA:3.40.1090.10 2 229 1.4E-20 T 28-03-2018 CWR44_RS02575 10b923c504a8739da2bba93e5a19c8e2 430 PIRSF PIRSF004539 2 429 1.3E-122 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 CWR44_RS02575 10b923c504a8739da2bba93e5a19c8e2 430 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 7 367 6.1E-92 T 28-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 CWR44_RS01775 6861a7c26a5e2cd6fefd12c3e1218322 391 Pfam PF07690 Major Facilitator Superfamily 10 327 1.6E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS01775 6861a7c26a5e2cd6fefd12c3e1218322 391 Gene3D G3DSA:1.20.1250.20 3 196 1.0E-26 T 28-03-2018 CWR44_RS01775 6861a7c26a5e2cd6fefd12c3e1218322 391 SUPERFAMILY SSF103473 6 385 1.96E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01775 6861a7c26a5e2cd6fefd12c3e1218322 391 Gene3D G3DSA:1.20.1250.20 201 388 2.2E-18 T 28-03-2018 CWR44_RS07065 4b9bafffc020bb46bb23945ac8f49bee 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 6.1E-12 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS07065 4b9bafffc020bb46bb23945ac8f49bee 438 Pfam PF01610 Transposase 164 417 2.9E-55 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS07065 4b9bafffc020bb46bb23945ac8f49bee 438 Gene3D G3DSA:1.10.10.60 81 153 0.01 T 28-03-2018 CWR44_RS01270 4b9bafffc020bb46bb23945ac8f49bee 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 6.1E-12 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS01270 4b9bafffc020bb46bb23945ac8f49bee 438 Pfam PF01610 Transposase 164 417 2.9E-55 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS01270 4b9bafffc020bb46bb23945ac8f49bee 438 Gene3D G3DSA:1.10.10.60 81 153 0.01 T 28-03-2018 CWR44_RS02400 07930d1ea7931b5c92d8fa36276224ea 74 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 1 69 1.1E-5 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CWR44_RS02400 07930d1ea7931b5c92d8fa36276224ea 74 SUPERFAMILY SSF49785 2 73 9.92E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like CWR44_RS02400 07930d1ea7931b5c92d8fa36276224ea 74 Gene3D G3DSA:2.60.120.260 1 73 3.5E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like CWR44_RS11775 d3d282dbbe4054a37ac91ee3b6c934e0 237 TIGRFAM TIGR02134 transald_staph: transaldolase 1 237 4.8E-131 T 28-03-2018 IPR011861 Transaldolase, Staphylococcus-type CWR44_RS11775 d3d282dbbe4054a37ac91ee3b6c934e0 237 Gene3D G3DSA:3.20.20.70 6 233 1.7E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS11775 d3d282dbbe4054a37ac91ee3b6c934e0 237 SUPERFAMILY SSF51569 7 231 2.81E-48 T 28-03-2018 CWR44_RS11775 d3d282dbbe4054a37ac91ee3b6c934e0 237 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 8 212 4.9E-37 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CWR44_RS04705 3ce36e7c0a12370bf4f809aa1e26b033 498 Gene3D G3DSA:3.50.50.60 1 442 2.8E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04705 3ce36e7c0a12370bf4f809aa1e26b033 498 SUPERFAMILY SSF51905 4 274 1.3E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04705 3ce36e7c0a12370bf4f809aa1e26b033 498 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 492 5.1E-214 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS04705 3ce36e7c0a12370bf4f809aa1e26b033 498 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 9 489 1.5E-186 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS04705 3ce36e7c0a12370bf4f809aa1e26b033 498 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 3 492 50.683 T 28-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CWR44_RS02130 8a99afe4ea989a3906c9ee43a1c71b81 323 Gene3D G3DSA:3.40.50.1820 31 322 7.2E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS02130 8a99afe4ea989a3906c9ee43a1c71b81 323 Pfam PF07859 alpha/beta hydrolase fold 102 302 2.9E-26 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CWR44_RS02130 8a99afe4ea989a3906c9ee43a1c71b81 323 SUPERFAMILY SSF53474 71 308 1.69E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS04385 628e533bd8f9814a5d00a77c1b1ad82c 655 SMART SM00267 128 297 1.2E-5 T 28-03-2018 IPR000160 GGDEF domain CWR44_RS04385 628e533bd8f9814a5d00a77c1b1ad82c 655 PIRSF PIRSF026583 1 655 4.4E-260 T 28-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CWR44_RS04385 628e533bd8f9814a5d00a77c1b1ad82c 655 Gene3D G3DSA:3.30.70.270 121 287 0.0011 T 28-03-2018 CWR44_RS04385 628e533bd8f9814a5d00a77c1b1ad82c 655 Pfam PF02272 DHHA1 domain 516 645 4.6E-12 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWR44_RS04385 628e533bd8f9814a5d00a77c1b1ad82c 655 SUPERFAMILY SSF64182 336 640 1.31E-68 T 28-03-2018 CWR44_RS04385 628e533bd8f9814a5d00a77c1b1ad82c 655 Pfam PF01368 DHH family 337 494 4.5E-22 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR44_RS04385 628e533bd8f9814a5d00a77c1b1ad82c 655 Gene3D G3DSA:3.90.1640.10 315 533 3.1E-44 T 28-03-2018 CWR44_RS11095 df2e988e8775450446532b98e4c3f485 379 Pfam PF01702 Queuine tRNA-ribosyltransferase 131 365 9.6E-97 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR44_RS11095 df2e988e8775450446532b98e4c3f485 379 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 372 1.4E-182 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR44_RS11095 df2e988e8775450446532b98e4c3f485 379 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 372 8.0E-173 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR44_RS11095 df2e988e8775450446532b98e4c3f485 379 SUPERFAMILY SSF51713 2 369 1.7E-165 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR44_RS11095 df2e988e8775450446532b98e4c3f485 379 Gene3D G3DSA:3.20.20.105 1 372 2.6E-167 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR44_RS11095 df2e988e8775450446532b98e4c3f485 379 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 57.718 T 28-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR44_RS08355 bf1eadabd1fcdfd7f33d3c6299440243 96 Pfam PF02325 YGGT family 15 81 7.2E-19 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CWR44_RS09595 07b406b5a92d74d3ca417fa4b1aa1355 166 Pfam PF14489 QueF-like protein 63 141 2.9E-34 T 28-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CWR44_RS09595 07b406b5a92d74d3ca417fa4b1aa1355 166 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 166 67.769 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CWR44_RS09595 07b406b5a92d74d3ca417fa4b1aa1355 166 SUPERFAMILY SSF55620 30 136 6.15E-27 T 28-03-2018 CWR44_RS09595 07b406b5a92d74d3ca417fa4b1aa1355 166 PIRSF PIRSF027377 8 148 1.0E-60 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CWR44_RS09595 07b406b5a92d74d3ca417fa4b1aa1355 166 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 29 140 5.3E-51 T 28-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CWR44_RS09595 07b406b5a92d74d3ca417fa4b1aa1355 166 Gene3D G3DSA:3.30.1130.10 22 166 5.1E-41 T 28-03-2018 CWR44_RS08550 c702257bdf8b109f3f3490c6a0ba56b3 186 SUPERFAMILY SSF54637 73 179 8.8E-19 T 28-03-2018 IPR029069 HotDog domain CWR44_RS08550 c702257bdf8b109f3f3490c6a0ba56b3 186 Gene3D G3DSA:3.10.129.10 60 185 2.4E-16 T 28-03-2018 CWR44_RS08550 c702257bdf8b109f3f3490c6a0ba56b3 186 Pfam PF01575 MaoC like domain 100 167 1.5E-5 T 28-03-2018 IPR002539 MaoC-like domain CWR44_RS08550 c702257bdf8b109f3f3490c6a0ba56b3 186 Gene3D G3DSA:1.10.10.10 1 59 1.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS08550 c702257bdf8b109f3f3490c6a0ba56b3 186 PIRSF PIRSF037733 1 186 1.9E-81 T 28-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CWR44_RS00715 f6404296baca6893d4cd172a59d9a723 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 1.2E-48 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS00715 f6404296baca6893d4cd172a59d9a723 120 Gene3D G3DSA:3.30.420.100 2 120 2.8E-41 T 28-03-2018 CWR44_RS00715 f6404296baca6893d4cd172a59d9a723 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 2.3E-43 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS00715 f6404296baca6893d4cd172a59d9a723 120 SUPERFAMILY SSF53137 7 118 4.36E-51 T 28-03-2018 CWR44_RS00715 f6404296baca6893d4cd172a59d9a723 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 29.026 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS04450 f05bac1df87f819c12367766cb9808ed 45 Pfam PF00468 Ribosomal protein L34 3 45 7.8E-23 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04450 f05bac1df87f819c12367766cb9808ed 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 3 45 7.9E-20 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04450 f05bac1df87f819c12367766cb9808ed 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 2 45 15.729 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04450 f05bac1df87f819c12367766cb9808ed 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 3 22 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS04450 f05bac1df87f819c12367766cb9808ed 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 3 27 2.0E-7 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS01800 ebde3ffa96beeeaa4bdc4a930491fb2d 220 SUPERFAMILY SSF52540 2 213 2.06E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS01800 ebde3ffa96beeeaa4bdc4a930491fb2d 220 Gene3D G3DSA:3.40.50.300 1 218 1.6E-58 T 28-03-2018 CWR44_RS01800 ebde3ffa96beeeaa4bdc4a930491fb2d 220 Pfam PF00005 ABC transporter 18 161 5.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS01800 ebde3ffa96beeeaa4bdc4a930491fb2d 220 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS01800 ebde3ffa96beeeaa4bdc4a930491fb2d 220 SMART SM00382 27 209 1.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03885 a5d17bf7daf1ddc202bf637b365e2fb5 631 Gene3D G3DSA:3.90.550.10 1 269 2.9E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS03885 a5d17bf7daf1ddc202bf637b365e2fb5 631 Pfam PF00535 Glycosyl transferase family 2 6 136 6.2E-31 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR44_RS03885 a5d17bf7daf1ddc202bf637b365e2fb5 631 SUPERFAMILY SSF53448 4 217 2.16E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS00355 f7f59cac85945112fc963bddcc9a2b5f 218 SUPERFAMILY SSF51735 1 206 7.54E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS00355 f7f59cac85945112fc963bddcc9a2b5f 218 Gene3D G3DSA:3.40.50.720 2 217 2.6E-26 T 28-03-2018 CWR44_RS00355 f7f59cac85945112fc963bddcc9a2b5f 218 Pfam PF13460 NAD(P)H-binding 7 190 9.3E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS00745 99117df0c18e38d69f773cffe1742505 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 8.0E-58 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CWR44_RS00745 99117df0c18e38d69f773cffe1742505 122 Gene3D G3DSA:2.40.150.20 1 122 1.6E-51 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWR44_RS00745 99117df0c18e38d69f773cffe1742505 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.1E-53 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWR44_RS00745 99117df0c18e38d69f773cffe1742505 122 SUPERFAMILY SSF50193 1 122 8.11E-50 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWR44_RS00745 99117df0c18e38d69f773cffe1742505 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.949 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWR44_RS00745 99117df0c18e38d69f773cffe1742505 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00745 99117df0c18e38d69f773cffe1742505 122 SMART SM01374 1 122 4.4E-84 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CWR44_RS11585 6f0afe216b3b7bcf05b3fd4ccb6bbc65 285 PIRSF PIRSF012562 1 265 1.6E-133 T 28-03-2018 IPR010838 Protein of unknown unction DUF1444 CWR44_RS11585 6f0afe216b3b7bcf05b3fd4ccb6bbc65 285 Pfam PF07285 Protein of unknown function (DUF1444) 1 263 1.5E-123 T 28-03-2018 IPR010838 Protein of unknown unction DUF1444 CWR44_RS11585 6f0afe216b3b7bcf05b3fd4ccb6bbc65 285 Hamap MF_01548 UPF0354 protein . 1 266 44.469 T 28-03-2018 IPR010838 Protein of unknown unction DUF1444 CWR44_RS05410 1f1b0c95e1d421e8e137c4616aac2167 159 SUPERFAMILY SSF55083 1 148 1.28E-55 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWR44_RS05410 1f1b0c95e1d421e8e137c4616aac2167 159 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 133 1.7E-39 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWR44_RS05410 1f1b0c95e1d421e8e137c4616aac2167 159 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 133 2.2E-48 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWR44_RS05410 1f1b0c95e1d421e8e137c4616aac2167 159 Gene3D G3DSA:3.30.70.560 1 156 1.1E-61 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWR44_RS05410 1f1b0c95e1d421e8e137c4616aac2167 159 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 88 99 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CWR44_RS02320 2886c971b0f1789598ba671fa8bc1c97 187 Pfam PF01551 Peptidase family M23 70 160 1.1E-24 T 28-03-2018 IPR016047 Peptidase M23 CWR44_RS02320 2886c971b0f1789598ba671fa8bc1c97 187 SUPERFAMILY SSF51261 36 174 1.15E-36 T 28-03-2018 IPR011055 Duplicated hybrid motif CWR44_RS02320 2886c971b0f1789598ba671fa8bc1c97 187 Gene3D G3DSA:2.70.70.10 29 177 1.9E-32 T 28-03-2018 CWR44_RS11500 bdd29c8076981a1a1da2289712aa5391 207 SUPERFAMILY SSF69593 16 198 4.97E-36 T 28-03-2018 CWR44_RS11500 bdd29c8076981a1a1da2289712aa5391 207 Pfam PF01553 Acyltransferase 21 143 1.5E-20 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CWR44_RS11500 bdd29c8076981a1a1da2289712aa5391 207 SMART SM00563 34 146 1.9E-20 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CWR44_RS11500 bdd29c8076981a1a1da2289712aa5391 207 Gene3D G3DSA:3.40.1130.10 1 206 2.8E-34 T 28-03-2018 CWR44_RS11470 3ae658a9e53d0ac4cb13e43b1f88c2a3 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 15 243 2.6E-44 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CWR44_RS11470 3ae658a9e53d0ac4cb13e43b1f88c2a3 248 SUPERFAMILY SSF51695 9 244 5.76E-71 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR44_RS11470 3ae658a9e53d0ac4cb13e43b1f88c2a3 248 Gene3D G3DSA:3.20.20.190 2 248 5.6E-73 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CWR44_RS08885 28317962d0b9207c398a9d44ef204df4 163 Pfam PF09512 Thiamine-precursor transporter protein (ThiW) 6 154 2.7E-52 T 28-03-2018 IPR012652 Energy coupling factor transporter S component ThiW CWR44_RS08885 28317962d0b9207c398a9d44ef204df4 163 PIRSF PIRSF024534 1 163 2.1E-66 T 28-03-2018 IPR012652 Energy coupling factor transporter S component ThiW CWR44_RS08885 28317962d0b9207c398a9d44ef204df4 163 TIGRFAM TIGR02359 thiW: energy coupling factor transporter S component ThiW 4 158 1.2E-62 T 28-03-2018 IPR012652 Energy coupling factor transporter S component ThiW CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 TIGRFAM TIGR00277 HDIG: HDIG domain 331 408 4.6E-24 T 28-03-2018 IPR006675 HDIG domain CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 Pfam PF12072 Domain of unknown function (DUF3552) 6 204 3.4E-63 T 28-03-2018 IPR022711 Ribonuclease Y, N-terminal CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 Gene3D G3DSA:1.10.3210.10 244 477 8.8E-36 T 28-03-2018 CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 Gene3D G3DSA:3.30.300.20 167 243 4.1E-12 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 SMART SM00322 207 274 6.2E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 Pfam PF01966 HD domain 336 427 9.6E-19 T 28-03-2018 IPR006674 HD domain CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 SUPERFAMILY SSF54791 206 303 5.43E-17 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 Hamap MF_00335 Ribonuclease Y [rny]. 4 519 25.465 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 SUPERFAMILY SSF109604 312 469 3.37E-29 T 28-03-2018 CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 SMART SM00471 331 437 5.0E-12 T 28-03-2018 IPR003607 HD/PDEase domain CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 Pfam PF00013 KH domain 212 268 1.9E-6 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CWR44_RS08840 2b610a0d2a6e52b074d908e3ecf92ef9 519 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 7 519 2.7E-240 T 28-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CWR44_RS11390 769d12a14ff355835b6c90cac8df2e90 137 PRINTS PR01438 Universal stress protein signature 2 20 3.5E-12 T 28-03-2018 IPR006015 Universal stress protein A CWR44_RS11390 769d12a14ff355835b6c90cac8df2e90 137 PRINTS PR01438 Universal stress protein signature 115 137 3.5E-12 T 28-03-2018 IPR006015 Universal stress protein A CWR44_RS11390 769d12a14ff355835b6c90cac8df2e90 137 PRINTS PR01438 Universal stress protein signature 97 109 3.5E-12 T 28-03-2018 IPR006015 Universal stress protein A CWR44_RS11390 769d12a14ff355835b6c90cac8df2e90 137 Gene3D G3DSA:3.40.50.620 2 137 2.1E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS11390 769d12a14ff355835b6c90cac8df2e90 137 Pfam PF00582 Universal stress protein family 1 137 7.1E-22 T 28-03-2018 IPR006016 UspA GO:0006950 CWR44_RS11390 769d12a14ff355835b6c90cac8df2e90 137 SUPERFAMILY SSF52402 1 137 3.35E-22 T 28-03-2018 CWR44_RS06370 95067be684cbc67168343065ae7a39c3 119 SUPERFAMILY SSF46785 2 117 1.75E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06370 95067be684cbc67168343065ae7a39c3 119 TIGRFAM TIGR01889 Staph_reg_Sar: staphylococcal accessory regulator family 7 117 1.7E-25 T 28-03-2018 IPR010166 Transcriptional regulator SarA/Rot GO:0006355 CWR44_RS06370 95067be684cbc67168343065ae7a39c3 119 Gene3D G3DSA:1.10.10.10 1 118 4.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02650 f271eff6b9cb8b15490963af16b2d9af 396 Pfam PF13273 Protein of unknown function (DUF4064) 19 125 1.5E-18 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CWR44_RS02810 54bfb69914b5cbbdea25c3258c5d2deb 239 Pfam PF06114 IrrE N-terminal-like domain 39 156 1.8E-17 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CWR44_RS03485 b25289a411fd2de046cc84c7ab5fb946 135 Gene3D G3DSA:1.20.1290.10 2 66 1.4E-6 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CWR44_RS03485 b25289a411fd2de046cc84c7ab5fb946 135 SUPERFAMILY SSF69118 5 134 4.48E-19 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CWR44_RS03485 b25289a411fd2de046cc84c7ab5fb946 135 Gene3D G3DSA:1.20.1290.10 67 135 1.8E-4 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CWR44_RS07525 ac3056c49c579a11b95e7e327c8f469c 265 Pfam PF13743 Thioredoxin 27 189 1.2E-42 T 28-03-2018 CWR44_RS07525 ac3056c49c579a11b95e7e327c8f469c 265 SUPERFAMILY SSF52833 24 198 6.71E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS07525 ac3056c49c579a11b95e7e327c8f469c 265 Gene3D G3DSA:3.40.30.10 3 203 9.3E-12 T 28-03-2018 CWR44_RS04285 9785970aae952ef85b0f29d652d3528a 142 SUPERFAMILY SSF54637 2 139 2.33E-31 T 28-03-2018 IPR029069 HotDog domain CWR44_RS04285 9785970aae952ef85b0f29d652d3528a 142 Gene3D G3DSA:3.10.129.10 1 142 2.0E-27 T 28-03-2018 CWR44_RS04285 9785970aae952ef85b0f29d652d3528a 142 Pfam PF01575 MaoC like domain 8 121 7.9E-33 T 28-03-2018 IPR002539 MaoC-like domain CWR44_RS02660 d2d2cf124b5f0cdd66aabe445c5a7192 249 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS02660 d2d2cf124b5f0cdd66aabe445c5a7192 249 SUPERFAMILY SSF52540 2 223 1.02E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS02660 d2d2cf124b5f0cdd66aabe445c5a7192 249 Pfam PF00005 ABC transporter 22 170 6.5E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS02660 d2d2cf124b5f0cdd66aabe445c5a7192 249 SMART SM00382 31 218 6.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS02660 d2d2cf124b5f0cdd66aabe445c5a7192 249 Gene3D G3DSA:3.40.50.300 1 241 9.1E-63 T 28-03-2018 CWR44_RS00460 416967127b915bfa05dc19de6fe3dd6f 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 6.1E-12 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS00460 416967127b915bfa05dc19de6fe3dd6f 438 Gene3D G3DSA:1.10.10.60 81 154 0.0077 T 28-03-2018 CWR44_RS00460 416967127b915bfa05dc19de6fe3dd6f 438 Pfam PF01610 Transposase 164 417 2.9E-55 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS10185 b7de18ddfa2e1ca6a206e12bab161416 212 Pfam PF13460 NAD(P)H-binding 8 188 1.0E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10185 b7de18ddfa2e1ca6a206e12bab161416 212 SUPERFAMILY SSF51735 1 193 2.0E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10185 b7de18ddfa2e1ca6a206e12bab161416 212 Gene3D G3DSA:3.40.50.720 1 203 6.1E-19 T 28-03-2018 CWR44_RS06020 af71d99d5ccddc32a4c70ae7a0f2b3a4 331 Pfam PF03601 Conserved hypothetical protein 698 12 310 2.8E-89 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CWR44_RS01350 ee4628de7e65a35b7be63fbc7bd83ddb 77 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 31 50 1.4E-5 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CWR44_RS01350 ee4628de7e65a35b7be63fbc7bd83ddb 77 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 50 68 1.4E-5 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CWR44_RS01350 ee4628de7e65a35b7be63fbc7bd83ddb 77 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 11 31 1.4E-5 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CWR44_RS01350 ee4628de7e65a35b7be63fbc7bd83ddb 77 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 11 74 15.781 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CWR44_RS01350 ee4628de7e65a35b7be63fbc7bd83ddb 77 Pfam PF02416 mttA/Hcf106 family 14 61 8.9E-18 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CWR44_RS01350 ee4628de7e65a35b7be63fbc7bd83ddb 77 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 13 58 1.6E-18 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CWR44_RS06555 04c6248e48d135cd5592d6fb55877c08 329 Gene3D G3DSA:3.90.550.10 3 228 1.2E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS06555 04c6248e48d135cd5592d6fb55877c08 329 SUPERFAMILY SSF53448 1 255 4.97E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS06555 04c6248e48d135cd5592d6fb55877c08 329 Pfam PF00535 Glycosyl transferase family 2 5 170 4.7E-31 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR44_RS08330 4000d2de21cc00d707cafe5d7aa6727a 477 Hamap MF_02033 Cell division protein FtsA [ftsA]. 2 476 22.184 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CWR44_RS08330 4000d2de21cc00d707cafe5d7aa6727a 477 PIRSF PIRSF003101 1 476 2.8E-87 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CWR44_RS08330 4000d2de21cc00d707cafe5d7aa6727a 477 Gene3D G3DSA:3.30.420.40 1 182 2.8E-21 T 28-03-2018 CWR44_RS08330 4000d2de21cc00d707cafe5d7aa6727a 477 Gene3D G3DSA:3.30.420.150 197 407 5.5E-19 T 28-03-2018 CWR44_RS08330 4000d2de21cc00d707cafe5d7aa6727a 477 SMART SM00842 6 193 1.1E-44 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CWR44_RS08330 4000d2de21cc00d707cafe5d7aa6727a 477 SUPERFAMILY SSF53067 196 359 1.6E-33 T 28-03-2018 CWR44_RS08330 4000d2de21cc00d707cafe5d7aa6727a 477 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 6 364 4.2E-75 T 28-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CWR44_RS08330 4000d2de21cc00d707cafe5d7aa6727a 477 Pfam PF14450 Cell division protein FtsA 203 364 9.4E-18 T 28-03-2018 CWR44_RS08330 4000d2de21cc00d707cafe5d7aa6727a 477 Pfam PF02491 SHS2 domain inserted in FTSA 84 158 3.5E-10 T 28-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CWR44_RS08330 4000d2de21cc00d707cafe5d7aa6727a 477 SUPERFAMILY SSF53067 5 187 1.3E-35 T 28-03-2018 CWR44_RS02540 58651a3bcef989ece799a846cdd2289a 460 Gene3D G3DSA:1.20.1250.20 259 460 4.5E-23 T 28-03-2018 CWR44_RS02540 58651a3bcef989ece799a846cdd2289a 460 Gene3D G3DSA:1.20.1250.20 9 202 1.4E-26 T 28-03-2018 CWR44_RS02540 58651a3bcef989ece799a846cdd2289a 460 SUPERFAMILY SSF103473 250 457 1.18E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS02540 58651a3bcef989ece799a846cdd2289a 460 SUPERFAMILY SSF103473 3 202 1.18E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS02540 58651a3bcef989ece799a846cdd2289a 460 Pfam PF07690 Major Facilitator Superfamily 20 411 7.9E-45 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS12185 996445461cf0a85250a697c050a89816 151 PIRSF PIRSF000239 1 150 6.8E-27 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CWR44_RS12185 996445461cf0a85250a697c050a89816 151 Pfam PF00578 AhpC/TSA family 5 131 1.9E-37 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CWR44_RS12185 996445461cf0a85250a697c050a89816 151 Gene3D G3DSA:3.40.30.10 1 151 2.0E-37 T 28-03-2018 CWR44_RS12185 996445461cf0a85250a697c050a89816 151 SUPERFAMILY SSF52833 1 150 4.99E-48 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 5.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 5.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 5.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 5.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 5.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 SUPERFAMILY SSF51735 6 254 2.48E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 Gene3D G3DSA:3.40.50.720 1 47 4.2E-10 T 28-03-2018 CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 Gene3D G3DSA:3.40.50.720 48 258 1.3E-59 T 28-03-2018 CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 3.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 3.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 3.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS00830 c2bce1d28f65ce221878186a2f1e6eed 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 253 1.2E-65 T 28-03-2018 CWR44_RS04535 dde75edc550e471c4fd702c44eebe842 468 PIRSF PIRSF032522 1 424 5.3E-56 T 28-03-2018 IPR023599 Membrane-associated protein TcaA GO:0016021|GO:0046677 CWR44_RS04535 dde75edc550e471c4fd702c44eebe842 468 Gene3D G3DSA:2.20.70.10 1 23 0.005 T 28-03-2018 CWR44_RS04535 dde75edc550e471c4fd702c44eebe842 468 Gene3D G3DSA:2.60.120.10 221 304 0.035 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWR44_RS04535 dde75edc550e471c4fd702c44eebe842 468 Pfam PF13248 zinc-ribbon domain 1 24 1.6E-7 T 28-03-2018 CWR44_RS03045 dba109f5209b9ba37bf7666dcd043bbd 257 SMART SM00382 29 225 5.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS03045 dba109f5209b9ba37bf7666dcd043bbd 257 Pfam PF00005 ABC transporter 20 176 1.9E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS03045 dba109f5209b9ba37bf7666dcd043bbd 257 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 4 245 6.2E-111 T 28-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 CWR44_RS03045 dba109f5209b9ba37bf7666dcd043bbd 257 SUPERFAMILY SSF52540 4 239 3.19E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03045 dba109f5209b9ba37bf7666dcd043bbd 257 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS03045 dba109f5209b9ba37bf7666dcd043bbd 257 Gene3D G3DSA:3.40.50.300 1 254 7.1E-59 T 28-03-2018 CWR44_RS11430 53a864f169de5b28095718c111f3b999 164 Pfam PF08534 Redoxin 20 158 5.8E-26 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CWR44_RS11430 53a864f169de5b28095718c111f3b999 164 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 162 36.319 T 28-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CWR44_RS11430 53a864f169de5b28095718c111f3b999 164 Gene3D G3DSA:3.40.30.10 6 164 4.0E-24 T 28-03-2018 CWR44_RS11430 53a864f169de5b28095718c111f3b999 164 ProSitePatterns PS01265 Tpx family signature. 82 93 - T 28-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CWR44_RS11430 53a864f169de5b28095718c111f3b999 164 SUPERFAMILY SSF52833 1 159 5.22E-42 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS09615 0660371e9562f3db406ad54199e1ca07 146 SUPERFAMILY SSF55620 11 132 1.17E-28 T 28-03-2018 CWR44_RS09615 0660371e9562f3db406ad54199e1ca07 146 PIRSF PIRSF006113 12 135 1.2E-23 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CWR44_RS09615 0660371e9562f3db406ad54199e1ca07 146 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 134 1.0E-27 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CWR44_RS09615 0660371e9562f3db406ad54199e1ca07 146 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 16 105 1.9E-27 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CWR44_RS09615 0660371e9562f3db406ad54199e1ca07 146 Gene3D G3DSA:3.30.479.10 3 136 6.3E-30 T 28-03-2018 CWR44_RS01740 0402c1f342fdd3ae94e4a650b405c40d 315 Gene3D G3DSA:3.40.190.10 183 307 2.7E-23 T 28-03-2018 CWR44_RS01740 0402c1f342fdd3ae94e4a650b405c40d 315 SUPERFAMILY SSF53850 33 304 6.24E-63 T 28-03-2018 CWR44_RS01740 0402c1f342fdd3ae94e4a650b405c40d 315 Gene3D G3DSA:3.40.190.10 21 182 1.3E-27 T 28-03-2018 CWR44_RS01740 0402c1f342fdd3ae94e4a650b405c40d 315 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 33 301 2.5E-53 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CWR44_RS04280 f3187038c00ad9ea321520b2e8cfa9ae 669 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 27 141 9.6E-26 T 28-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CWR44_RS04280 f3187038c00ad9ea321520b2e8cfa9ae 669 SUPERFAMILY SSF56601 329 662 1.85E-74 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR44_RS04280 f3187038c00ad9ea321520b2e8cfa9ae 669 Pfam PF03717 Penicillin-binding Protein dimerisation domain 149 310 1.3E-29 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR44_RS04280 f3187038c00ad9ea321520b2e8cfa9ae 669 Pfam PF00905 Penicillin binding protein transpeptidase domain 347 658 3.3E-71 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CWR44_RS04280 f3187038c00ad9ea321520b2e8cfa9ae 669 Gene3D G3DSA:3.10.450.100 24 136 3.2E-22 T 28-03-2018 CWR44_RS04280 f3187038c00ad9ea321520b2e8cfa9ae 669 SUPERFAMILY SSF56519 141 328 1.83E-41 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CWR44_RS04280 f3187038c00ad9ea321520b2e8cfa9ae 669 Gene3D G3DSA:3.40.710.10 329 666 3.4E-59 T 28-03-2018 CWR44_RS04280 f3187038c00ad9ea321520b2e8cfa9ae 669 Gene3D G3DSA:3.90.1310.10 137 328 8.4E-29 T 28-03-2018 CWR44_RS04280 f3187038c00ad9ea321520b2e8cfa9ae 669 SUPERFAMILY SSF54427 28 139 5.7E-28 T 28-03-2018 IPR032710 NTF2-like domain CWR44_RS07095 fe3c9a2f7c8870836eac31d9e70159cc 126 SUPERFAMILY SSF51230 3 125 1.75E-47 T 28-03-2018 IPR011053 Single hybrid motif CWR44_RS07095 fe3c9a2f7c8870836eac31d9e70159cc 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CWR44_RS07095 fe3c9a2f7c8870836eac31d9e70159cc 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 41.605 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CWR44_RS07095 fe3c9a2f7c8870836eac31d9e70159cc 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 124 1.5E-55 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CWR44_RS07095 fe3c9a2f7c8870836eac31d9e70159cc 126 Pfam PF01597 Glycine cleavage H-protein 7 124 3.3E-49 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CWR44_RS07095 fe3c9a2f7c8870836eac31d9e70159cc 126 Gene3D G3DSA:2.40.50.100 5 126 2.9E-50 T 28-03-2018 CWR44_RS06845 4772a439d0efed3aa8719e2477f69f34 311 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 3 301 4.5E-117 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CWR44_RS06845 4772a439d0efed3aa8719e2477f69f34 311 SUPERFAMILY SSF75138 2 128 5.89E-40 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CWR44_RS06845 4772a439d0efed3aa8719e2477f69f34 311 Gene3D G3DSA:3.40.50.300 131 305 1.6E-44 T 28-03-2018 CWR44_RS06845 4772a439d0efed3aa8719e2477f69f34 311 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 1 304 41.536 T 28-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CWR44_RS06845 4772a439d0efed3aa8719e2477f69f34 311 Pfam PF07475 HPr Serine kinase C-terminal domain 128 296 1.9E-75 T 28-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CWR44_RS06845 4772a439d0efed3aa8719e2477f69f34 311 SUPERFAMILY SSF53795 131 297 5.19E-40 T 28-03-2018 CWR44_RS06845 4772a439d0efed3aa8719e2477f69f34 311 Pfam PF02603 HPr Serine kinase N terminus 3 125 1.5E-39 T 28-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CWR44_RS06845 4772a439d0efed3aa8719e2477f69f34 311 Gene3D G3DSA:3.40.1390.20 2 127 3.8E-42 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CWR44_RS02085 9e94a17b9dea09fdd93d084f0753c185 495 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 129 141 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR44_RS02085 9e94a17b9dea09fdd93d084f0753c185 495 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 351 371 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR44_RS02085 9e94a17b9dea09fdd93d084f0753c185 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 253 438 1.1E-34 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CWR44_RS02085 9e94a17b9dea09fdd93d084f0753c185 495 SUPERFAMILY SSF53067 4 245 2.44E-65 T 28-03-2018 CWR44_RS02085 9e94a17b9dea09fdd93d084f0753c185 495 PIRSF PIRSF000538 2 492 3.1E-147 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CWR44_RS02085 9e94a17b9dea09fdd93d084f0753c185 495 SUPERFAMILY SSF53067 245 486 6.74E-68 T 28-03-2018 CWR44_RS02085 9e94a17b9dea09fdd93d084f0753c185 495 Gene3D G3DSA:3.30.420.40 4 240 3.5E-67 T 28-03-2018 CWR44_RS02085 9e94a17b9dea09fdd93d084f0753c185 495 Gene3D G3DSA:3.30.420.40 241 495 7.6E-62 T 28-03-2018 CWR44_RS02085 9e94a17b9dea09fdd93d084f0753c185 495 TIGRFAM TIGR01312 XylB: xylulokinase 6 480 8.3E-168 T 28-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 CWR44_RS02085 9e94a17b9dea09fdd93d084f0753c185 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 243 3.6E-59 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CWR44_RS00090 33b7b2201a7b7763b430de27b43e694a 212 SUPERFAMILY SSF51391 5 210 5.89E-62 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00090 33b7b2201a7b7763b430de27b43e694a 212 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 9 206 1.7E-57 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00090 33b7b2201a7b7763b430de27b43e694a 212 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 7 212 25.734 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00090 33b7b2201a7b7763b430de27b43e694a 212 Pfam PF02581 Thiamine monophosphate synthase 9 194 2.4E-55 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00090 33b7b2201a7b7763b430de27b43e694a 212 Gene3D G3DSA:3.20.20.70 2 211 1.9E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS11305 4c0b4c8779614bd433532f08d4dd1db6 202 Gene3D G3DSA:3.40.50.300 1 195 3.0E-43 T 28-03-2018 CWR44_RS11305 4c0b4c8779614bd433532f08d4dd1db6 202 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 4.4E-57 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CWR44_RS11305 4c0b4c8779614bd433532f08d4dd1db6 202 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 198 26.733 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CWR44_RS11305 4c0b4c8779614bd433532f08d4dd1db6 202 SUPERFAMILY SSF52540 1 192 8.53E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11305 4c0b4c8779614bd433532f08d4dd1db6 202 Pfam PF01121 Dephospho-CoA kinase 4 179 1.2E-57 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CWR44_RS01680 d369584f77f10a5659d28afdaca6a3a4 494 Pfam PF00144 Beta-lactamase 40 355 1.9E-68 T 28-03-2018 IPR001466 Beta-lactamase-related CWR44_RS01680 d369584f77f10a5659d28afdaca6a3a4 494 Gene3D G3DSA:3.40.710.10 28 368 2.7E-83 T 28-03-2018 CWR44_RS01680 d369584f77f10a5659d28afdaca6a3a4 494 SUPERFAMILY SSF56601 37 365 4.18E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR44_RS07475 efc6e1c2ffa32f1f9cb6d1a1d6823ef8 355 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 49 100 8.9E-16 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CWR44_RS07475 efc6e1c2ffa32f1f9cb6d1a1d6823ef8 355 Gene3D G3DSA:1.10.3720.10 62 355 3.5E-44 T 28-03-2018 CWR44_RS07475 efc6e1c2ffa32f1f9cb6d1a1d6823ef8 355 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 171 355 3.7E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS07475 efc6e1c2ffa32f1f9cb6d1a1d6823ef8 355 SUPERFAMILY SSF161098 146 335 1.15E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 SUPERFAMILY SSF82057 1050 1116 6.71E-6 T 28-03-2018 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Gene3D G3DSA:2.30.30.170 720 796 2.6E-7 T 28-03-2018 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Gene3D G3DSA:2.30.30.170 558 626 6.6E-6 T 28-03-2018 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Gene3D G3DSA:2.30.30.170 970 1040 4.1E-14 T 28-03-2018 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Gene3D G3DSA:2.30.30.170 801 869 8.3E-7 T 28-03-2018 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Gene3D G3DSA:2.30.30.170 635 705 1.4E-12 T 28-03-2018 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Gene3D G3DSA:1.10.530.10 1192 1349 4.7E-22 T 28-03-2018 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 1209 1344 7.7E-13 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 SUPERFAMILY SSF55846 356 514 3.02E-35 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 SMART SM00644 356 497 1.9E-40 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 SMART SM00047 1196 1355 2.1E-55 T 28-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Gene3D G3DSA:2.30.30.170 890 965 9.0E-9 T 28-03-2018 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Gene3D G3DSA:2.30.30.170 1045 1118 5.8E-10 T 28-03-2018 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Pfam PF13457 SH3-like domain 637 701 4.2 T 28-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Pfam PF13457 SH3-like domain 893 963 1.7E-4 T 28-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Pfam PF13457 SH3-like domain 811 869 8.5 T 28-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Pfam PF13457 SH3-like domain 969 1038 3.8E-6 T 28-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Pfam PF13457 SH3-like domain 566 624 6.1E-4 T 28-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Pfam PF13457 SH3-like domain 726 794 0.002 T 28-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Pfam PF13457 SH3-like domain 1051 1115 0.012 T 28-03-2018 IPR025987 GW domain KEGG: 00511+3.2.1.96 CWR44_RS07750 7e566a957ff0102e9bbad3159f1c1abb 1361 Gene3D G3DSA:3.40.80.10 348 527 4.6E-27 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CWR44_RS11535 d61f41b41bae8a87fa700a6165d104fe 569 Gene3D G3DSA:2.30.38.10 369 452 6.8E-19 T 28-03-2018 CWR44_RS11535 d61f41b41bae8a87fa700a6165d104fe 569 SUPERFAMILY SSF56801 17 561 4.06E-160 T 28-03-2018 CWR44_RS11535 d61f41b41bae8a87fa700a6165d104fe 569 Pfam PF00501 AMP-binding enzyme 55 458 4.4E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CWR44_RS11535 d61f41b41bae8a87fa700a6165d104fe 569 ProSitePatterns PS00455 Putative AMP-binding domain signature. 209 220 - T 28-03-2018 IPR020845 AMP-binding, conserved site CWR44_RS11535 d61f41b41bae8a87fa700a6165d104fe 569 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 546 5.3E-23 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CWR44_RS11535 d61f41b41bae8a87fa700a6165d104fe 569 Gene3D G3DSA:3.30.300.30 455 567 4.8E-26 T 28-03-2018 CWR44_RS11535 d61f41b41bae8a87fa700a6165d104fe 569 Gene3D G3DSA:3.40.50.980 41 214 2.6E-39 T 28-03-2018 CWR44_RS11535 d61f41b41bae8a87fa700a6165d104fe 569 Gene3D G3DSA:3.40.50.980 215 368 7.8E-42 T 28-03-2018 CWR44_RS06760 9c46d0b801d4e09660f2a8111f1b5833 164 Pfam PF12821 Threonine/Serine exporter, ThrE 8 134 3.4E-39 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CWR44_RS10775 c58ee3acd15c894e27a06926c56b6a02 153 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 149 7.5E-42 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CWR44_RS10775 c58ee3acd15c894e27a06926c56b6a02 153 Pfam PF02130 Uncharacterized protein family UPF0054 15 147 2.2E-46 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CWR44_RS10775 c58ee3acd15c894e27a06926c56b6a02 153 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 152 24.244 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CWR44_RS10775 c58ee3acd15c894e27a06926c56b6a02 153 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CWR44_RS10775 c58ee3acd15c894e27a06926c56b6a02 153 Gene3D G3DSA:3.40.390.30 1 153 1.2E-49 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CWR44_RS10775 c58ee3acd15c894e27a06926c56b6a02 153 SUPERFAMILY SSF55486 2 152 5.01E-45 T 28-03-2018 CWR44_RS04345 14220dcac2d6633d4105c9cab7ceb0c2 443 Pfam PF07435 YycH protein 5 440 3.6E-118 T 28-03-2018 IPR009996 Regulatory protein YycH CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 39.736 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 SUPERFAMILY SSF50249 2 136 2.57E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 PIRSF PIRSF002133 1 137 6.8E-48 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 PRINTS PR01034 Ribosomal protein S12 signature 123 135 3.1E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 PRINTS PR01034 Ribosomal protein S12 signature 40 55 3.1E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 PRINTS PR01034 Ribosomal protein S12 signature 71 90 3.1E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 PRINTS PR01034 Ribosomal protein S12 signature 107 123 3.1E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 PRINTS PR01034 Ribosomal protein S12 signature 55 70 3.1E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 PRINTS PR01034 Ribosomal protein S12 signature 90 107 3.1E-57 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 Gene3D G3DSA:2.40.50.140 1 137 8.7E-63 T 28-03-2018 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 Pfam PF00164 Ribosomal protein S12/S23 32 136 4.1E-36 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05650 5ff5bab3fd7ae42b10d715b441acadb8 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 1.4E-66 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS01705 3432ee244279e8290fb44e73c6bf4700 464 Pfam PF07690 Major Facilitator Superfamily 18 414 1.1E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS01705 3432ee244279e8290fb44e73c6bf4700 464 Gene3D G3DSA:1.20.1250.20 262 464 1.8E-24 T 28-03-2018 CWR44_RS01705 3432ee244279e8290fb44e73c6bf4700 464 SUPERFAMILY SSF103473 6 195 3.79E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01705 3432ee244279e8290fb44e73c6bf4700 464 SUPERFAMILY SSF103473 251 461 3.79E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS01705 3432ee244279e8290fb44e73c6bf4700 464 Gene3D G3DSA:1.20.1250.20 5 203 7.8E-32 T 28-03-2018 CWR44_RS10080 303a651b2c79f0991e09c1d92554f7c8 207 SMART SM00014 84 195 5.8E-24 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR44_RS10080 303a651b2c79f0991e09c1d92554f7c8 207 SUPERFAMILY SSF48317 7 199 1.06E-36 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR44_RS10080 303a651b2c79f0991e09c1d92554f7c8 207 Pfam PF01569 PAP2 superfamily 85 198 3.0E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR44_RS10080 303a651b2c79f0991e09c1d92554f7c8 207 Gene3D G3DSA:1.20.144.10 34 201 1.9E-25 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CWR44_RS02750 eb4b142aa26a2d0bb24ccad5383f5f97 255 PIRSF PIRSF016557 1 255 2.3E-95 T 28-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 CWR44_RS02750 eb4b142aa26a2d0bb24ccad5383f5f97 255 Gene3D G3DSA:3.20.20.140 1 241 1.2E-21 T 28-03-2018 CWR44_RS02750 eb4b142aa26a2d0bb24ccad5383f5f97 255 SUPERFAMILY SSF89550 1 229 2.35E-16 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CWR44_RS02665 1b7c561a0989ae960bd402930d25163c 298 Gene3D G3DSA:3.30.565.10 107 296 1.2E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS02665 1b7c561a0989ae960bd402930d25163c 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 224 238 2.9E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS02665 1b7c561a0989ae960bd402930d25163c 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 282 295 2.9E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS02665 1b7c561a0989ae960bd402930d25163c 298 PRINTS PR00344 Bacterial sensor protein C-terminal signature 258 276 2.9E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CWR44_RS02665 1b7c561a0989ae960bd402930d25163c 298 SMART SM00387 190 298 8.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS02665 1b7c561a0989ae960bd402930d25163c 298 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 197 296 9.0E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS02665 1b7c561a0989ae960bd402930d25163c 298 SUPERFAMILY SSF55874 150 296 5.24E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS08770 c23a86d255f352fa779d681822c50b83 323 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 22 311 2.9E-85 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CWR44_RS08770 c23a86d255f352fa779d681822c50b83 323 SUPERFAMILY SSF82114 173 312 9.37E-44 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWR44_RS08770 c23a86d255f352fa779d681822c50b83 323 Gene3D G3DSA:2.40.30.30 180 315 2.8E-39 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWR44_RS08770 c23a86d255f352fa779d681822c50b83 323 SMART SM00904 183 312 5.2E-56 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWR44_RS08770 c23a86d255f352fa779d681822c50b83 323 Pfam PF06574 FAD synthetase 17 166 3.6E-47 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CWR44_RS08770 c23a86d255f352fa779d681822c50b83 323 SUPERFAMILY SSF52374 20 176 2.13E-28 T 28-03-2018 CWR44_RS08770 c23a86d255f352fa779d681822c50b83 323 Gene3D G3DSA:3.40.50.620 1 179 2.1E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS08770 c23a86d255f352fa779d681822c50b83 323 Pfam PF01687 Riboflavin kinase 184 310 7.4E-36 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CWR44_RS08770 c23a86d255f352fa779d681822c50b83 323 PIRSF PIRSF004491 1 316 1.9E-96 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CWR44_RS04110 b762ed6cf5b102054ef7e2aeafae08d9 444 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 8 426 3.9E-39 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CWR44_RS04110 b762ed6cf5b102054ef7e2aeafae08d9 444 PIRSF PIRSF002744 2 436 6.1E-74 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CWR44_RS03080 679acab97047dacdaaf9e8df238d2540 67 SMART SM00530 4 59 7.0E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS03080 679acab97047dacdaaf9e8df238d2540 67 SUPERFAMILY SSF47413 2 65 2.95E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS03080 679acab97047dacdaaf9e8df238d2540 67 Gene3D G3DSA:1.10.3100.10 1 65 2.7E-16 T 28-03-2018 IPR027910 YdiL-like domain CWR44_RS03080 679acab97047dacdaaf9e8df238d2540 67 Pfam PF01381 Helix-turn-helix 5 56 6.8E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS06700 aeb6af3eb0f258030afa42f5dbc78822 322 Pfam PF01032 FecCD transport family 13 315 3.0E-64 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR44_RS06700 aeb6af3eb0f258030afa42f5dbc78822 322 SUPERFAMILY SSF81345 3 315 6.41E-66 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWR44_RS06700 aeb6af3eb0f258030afa42f5dbc78822 322 Gene3D G3DSA:1.10.3470.10 2 322 5.8E-44 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS01205 bb2028e9683eb2b7b4f113e62cc23448 65 SMART SM00530 3 58 1.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS01205 bb2028e9683eb2b7b4f113e62cc23448 65 Gene3D G3DSA:1.10.260.40 1 62 1.2E-17 T 28-03-2018 CWR44_RS01205 bb2028e9683eb2b7b4f113e62cc23448 65 Pfam PF01381 Helix-turn-helix 11 58 1.2E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS01205 bb2028e9683eb2b7b4f113e62cc23448 65 SUPERFAMILY SSF47413 2 60 1.23E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS05550 9e17e42ef8ab7d286c4c3affcb7bf543 355 Gene3D G3DSA:3.40.50.1010 161 288 9.2E-21 T 28-03-2018 IPR029060 PIN domain-like CWR44_RS05550 9e17e42ef8ab7d286c4c3affcb7bf543 355 SMART SM00670 159 264 4.0E-5 T 28-03-2018 IPR002716 PIN domain CWR44_RS05550 9e17e42ef8ab7d286c4c3affcb7bf543 355 Pfam PF01938 TRAM domain 289 334 2.5E-5 T 28-03-2018 IPR002792 TRAM domain CWR44_RS05550 9e17e42ef8ab7d286c4c3affcb7bf543 355 SUPERFAMILY SSF88723 161 285 4.32E-20 T 28-03-2018 IPR029060 PIN domain-like CWR44_RS09740 b323f43b650739cfcf5b3f04966443fd 95 TIGRFAM TIGR01598 holin_phiLC3: holin, phage phi LC3 family 7 92 1.7E-12 T 28-03-2018 IPR006485 Bacteriophage holin CWR44_RS09740 b323f43b650739cfcf5b3f04966443fd 95 Pfam PF04531 Bacteriophage holin 7 93 1.9E-16 T 28-03-2018 IPR006485 Bacteriophage holin CWR44_RS01935 f847a733fc5bd82fd3c904646c4ac4c1 94 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.3E-17 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CWR44_RS01935 f847a733fc5bd82fd3c904646c4ac4c1 94 Gene3D G3DSA:3.30.70.100 1 92 2.8E-19 T 28-03-2018 CWR44_RS01935 f847a733fc5bd82fd3c904646c4ac4c1 94 SUPERFAMILY SSF54909 1 89 6.04E-25 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CWR44_RS01550 90ced55436f5e6bc3deaa8729e630686 171 SMART SM00867 3 168 4.9E-56 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CWR44_RS01550 90ced55436f5e6bc3deaa8729e630686 171 Pfam PF04264 YceI-like domain 5 167 1.8E-40 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CWR44_RS01550 90ced55436f5e6bc3deaa8729e630686 171 Gene3D G3DSA:2.40.128.110 1 171 3.0E-47 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CWR44_RS01550 90ced55436f5e6bc3deaa8729e630686 171 SUPERFAMILY SSF101874 5 167 3.01E-45 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CWR44_RS11880 a5bf9b400faf5188e049e4b83af277be 186 SUPERFAMILY SSF53474 2 184 8.61E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS11880 a5bf9b400faf5188e049e4b83af277be 186 Gene3D G3DSA:3.40.50.1820 2 186 1.7E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS11880 a5bf9b400faf5188e049e4b83af277be 186 Pfam PF06821 Serine hydrolase 4 180 1.9E-15 T 28-03-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 CWR44_RS04625 3da5beda3c0e52831e579b001e2c5d79 170 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 35.723 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWR44_RS04625 3da5beda3c0e52831e579b001e2c5d79 170 Gene3D G3DSA:2.40.50.140 1 122 3.2E-40 T 28-03-2018 CWR44_RS04625 3da5beda3c0e52831e579b001e2c5d79 170 Pfam PF00436 Single-strand binding protein family 2 103 3.9E-36 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWR44_RS04625 3da5beda3c0e52831e579b001e2c5d79 170 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 170 2.0E-47 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWR44_RS04625 3da5beda3c0e52831e579b001e2c5d79 170 PIRSF PIRSF002070 1 159 2.5E-39 T 28-03-2018 CWR44_RS04625 3da5beda3c0e52831e579b001e2c5d79 170 SUPERFAMILY SSF50249 1 170 6.51E-55 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS05890 3bb4d6e7ea794014ab1956c8577ea76f 219 Gene3D G3DSA:3.40.470.10 1 219 1.2E-96 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR44_RS05890 3bb4d6e7ea794014ab1956c8577ea76f 219 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 52 61 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR44_RS05890 3bb4d6e7ea794014ab1956c8577ea76f 219 SUPERFAMILY SSF52141 2 214 1.53E-89 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR44_RS05890 3bb4d6e7ea794014ab1956c8577ea76f 219 SMART SM00986 44 203 2.0E-37 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR44_RS05890 3bb4d6e7ea794014ab1956c8577ea76f 219 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 13 214 38.687 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR44_RS05890 3bb4d6e7ea794014ab1956c8577ea76f 219 Pfam PF03167 Uracil DNA glycosylase superfamily 48 202 2.9E-26 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR44_RS05890 3bb4d6e7ea794014ab1956c8577ea76f 219 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 2 207 2.2E-80 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CWR44_RS05890 3bb4d6e7ea794014ab1956c8577ea76f 219 SMART SM00987 44 203 2.0E-37 T 28-03-2018 CWR44_RS06075 b9927fae142f2ad23fb7f766945fc7b8 303 Gene3D G3DSA:3.40.50.1980 45 154 2.9E-31 T 28-03-2018 CWR44_RS06075 b9927fae142f2ad23fb7f766945fc7b8 303 SUPERFAMILY SSF53807 46 301 2.55E-57 T 28-03-2018 CWR44_RS06075 b9927fae142f2ad23fb7f766945fc7b8 303 Pfam PF01497 Periplasmic binding protein 50 274 1.6E-35 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CWR44_RS06075 b9927fae142f2ad23fb7f766945fc7b8 303 Gene3D G3DSA:3.40.50.1980 155 303 2.0E-32 T 28-03-2018 CWR44_RS10400 ccf28421a27ecdb68feec03d43b3160d 179 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 177 5.2E-38 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWR44_RS10400 ccf28421a27ecdb68feec03d43b3160d 179 Gene3D G3DSA:1.10.10.10 2 75 5.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10400 ccf28421a27ecdb68feec03d43b3160d 179 Gene3D G3DSA:1.10.10.10 76 165 2.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10400 ccf28421a27ecdb68feec03d43b3160d 179 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 173 28.148 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWR44_RS10400 ccf28421a27ecdb68feec03d43b3160d 179 Pfam PF04079 Segregation and condensation complex subunit ScpB 6 156 9.3E-42 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWR44_RS10400 ccf28421a27ecdb68feec03d43b3160d 179 PIRSF PIRSF019345 1 176 2.2E-40 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CWR44_RS10400 ccf28421a27ecdb68feec03d43b3160d 179 SUPERFAMILY SSF46785 4 72 1.02E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10400 ccf28421a27ecdb68feec03d43b3160d 179 SUPERFAMILY SSF46785 76 148 1.63E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02010 028524961d87df2a57cd06a22be938f6 480 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS02010 028524961d87df2a57cd06a22be938f6 480 SUPERFAMILY SSF53720 5 478 7.33E-151 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR44_RS02010 028524961d87df2a57cd06a22be938f6 480 Gene3D G3DSA:3.40.605.10 1 266 2.5E-88 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS02010 028524961d87df2a57cd06a22be938f6 480 Gene3D G3DSA:3.40.309.10 267 445 3.2E-66 T 28-03-2018 CWR44_RS02010 028524961d87df2a57cd06a22be938f6 480 Pfam PF00171 Aldehyde dehydrogenase family 16 472 2.0E-158 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS00250 1688e9f1ad6403be94ee5156ddfc958e 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 411 5.6E-88 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR44_RS00250 1688e9f1ad6403be94ee5156ddfc958e 423 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4 419 1.8E-154 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00250 1688e9f1ad6403be94ee5156ddfc958e 423 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 3 421 38.952 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CWR44_RS00250 1688e9f1ad6403be94ee5156ddfc958e 423 SUPERFAMILY SSF55205 5 420 2.45E-122 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CWR44_RS00250 1688e9f1ad6403be94ee5156ddfc958e 423 Gene3D G3DSA:3.65.10.10 23 222 1.3E-42 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR44_RS00250 1688e9f1ad6403be94ee5156ddfc958e 423 Gene3D G3DSA:3.65.10.10 223 422 2.5E-44 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CWR44_RS00980 59449b8263cba7c5b935f8b4203941ce 242 SUPERFAMILY SSF46785 144 230 1.47E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00980 59449b8263cba7c5b935f8b4203941ce 242 Gene3D G3DSA:1.10.10.10 34 113 8.2E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00980 59449b8263cba7c5b935f8b4203941ce 242 Gene3D G3DSA:1.10.10.10 148 241 0.038 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00980 59449b8263cba7c5b935f8b4203941ce 242 SUPERFAMILY SSF46785 10 116 5.27E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10990 4884526c72917c86e2225c0774351427 876 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 856 0.0 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 Pfam PF02272 DHHA1 domain 735 873 6.0E-29 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 654 697 7.2E-17 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 1.8E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 1.8E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 1.8E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 1.8E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 1.8E-31 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 SUPERFAMILY SSF55681 5 245 2.04E-88 T 28-03-2018 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 876 177.072 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 Gene3D G3DSA:3.30.980.10 555 714 8.0E-45 T 28-03-2018 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 SUPERFAMILY SSF55186 553 708 4.19E-52 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 SUPERFAMILY SSF50447 454 553 2.35E-14 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CWR44_RS10990 4884526c72917c86e2225c0774351427 876 SMART SM00863 654 697 2.2E-20 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 Gene3D G3DSA:3.30.930.10 3 242 9.1E-96 T 28-03-2018 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 SUPERFAMILY SSF101353 246 461 2.35E-67 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CWR44_RS10990 4884526c72917c86e2225c0774351427 876 Pfam PF01411 tRNA synthetases class II (A) 8 555 2.4E-205 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CWR44_RS07250 c5a73f82e1e01c52a0655375bb03ddf7 106 Pfam PF07315 Protein of unknown function (DUF1462) 7 101 8.9E-39 T 28-03-2018 IPR009190 Protein of unknown function DUF1462 CWR44_RS07250 c5a73f82e1e01c52a0655375bb03ddf7 106 PIRSF PIRSF010603 1 106 1.5E-42 T 28-03-2018 IPR009190 Protein of unknown function DUF1462 CWR44_RS07250 c5a73f82e1e01c52a0655375bb03ddf7 106 Gene3D G3DSA:3.40.30.30 2 103 1.1E-39 T 28-03-2018 CWR44_RS07250 c5a73f82e1e01c52a0655375bb03ddf7 106 SUPERFAMILY SSF52833 1 104 5.93E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS02645 9f95661d2868f788039c4456d6b4be1e 398 Gene3D G3DSA:1.10.510.10 37 398 1.4E-4 T 28-03-2018 CWR44_RS11475 049cdb2c5589f6ce3fdf2e16d875f589 146 Gene3D G3DSA:3.30.300.20 1 146 2.3E-26 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CWR44_RS11475 049cdb2c5589f6ce3fdf2e16d875f589 146 TIGRFAM TIGR03563 perox_SACOL1771: peroxiredoxin, SACOL1771 subfamily 4 141 1.8E-65 T 28-03-2018 IPR019905 Peroxiredoxin OsmC-like protein, Firmicutes CWR44_RS11475 049cdb2c5589f6ce3fdf2e16d875f589 146 Pfam PF02566 OsmC-like protein 39 141 5.8E-17 T 28-03-2018 IPR003718 OsmC/Ohr family CWR44_RS11475 049cdb2c5589f6ce3fdf2e16d875f589 146 SUPERFAMILY SSF82784 2 141 6.54E-31 T 28-03-2018 IPR003718 OsmC/Ohr family CWR44_RS04215 fa99d6095bca0065eb7f9866002e25e9 156 Pfam PF07799 Protein of unknown function (DUF1643) 21 144 7.4E-23 T 28-03-2018 IPR012441 Protein of unknown function DUF1643 CWR44_RS04215 fa99d6095bca0065eb7f9866002e25e9 156 PIRSF PIRSF032209 1 153 1.2E-63 T 28-03-2018 IPR016992 Uncharacterised conserved protein UCP032209 CWR44_RS00800 02632d1b54eb37bf1a9b63f4056866e6 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 5.1E-46 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00800 02632d1b54eb37bf1a9b63f4056866e6 102 Gene3D G3DSA:3.30.70.600 3 102 9.7E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CWR44_RS00800 02632d1b54eb37bf1a9b63f4056866e6 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.778 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00800 02632d1b54eb37bf1a9b63f4056866e6 102 SUPERFAMILY SSF54999 5 102 8.76E-38 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CWR44_RS00800 02632d1b54eb37bf1a9b63f4056866e6 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00800 02632d1b54eb37bf1a9b63f4056866e6 102 SMART SM01403 7 101 1.4E-58 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CWR44_RS00800 02632d1b54eb37bf1a9b63f4056866e6 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 6.9E-36 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CWR44_RS00800 02632d1b54eb37bf1a9b63f4056866e6 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.1E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00800 02632d1b54eb37bf1a9b63f4056866e6 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.1E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00800 02632d1b54eb37bf1a9b63f4056866e6 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.1E-18 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS00275 af5af369fcfdbd0f1b7b041bdc2fc84e 286 Gene3D G3DSA:3.40.630.30 2 176 2.7E-17 T 28-03-2018 CWR44_RS00275 af5af369fcfdbd0f1b7b041bdc2fc84e 286 SUPERFAMILY SSF55729 8 152 9.39E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS00275 af5af369fcfdbd0f1b7b041bdc2fc84e 286 SUPERFAMILY SSF55729 188 276 1.77E-7 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS00275 af5af369fcfdbd0f1b7b041bdc2fc84e 286 Gene3D G3DSA:3.40.630.30 183 278 2.2E-5 T 28-03-2018 CWR44_RS00275 af5af369fcfdbd0f1b7b041bdc2fc84e 286 Pfam PF00583 Acetyltransferase (GNAT) family 35 144 2.4E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS11340 d80099e2bda543d43e11016a50dbaca5 452 PIRSF PIRSF006060 1 451 1.0E-65 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS11340 d80099e2bda543d43e11016a50dbaca5 452 Pfam PF00324 Amino acid permease 14 442 2.7E-106 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CWR44_RS07665 90907000d70c57101546874eaca886f2 438 Pfam PF01610 Transposase 164 417 2.7E-55 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS07665 90907000d70c57101546874eaca886f2 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 6.1E-12 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS02290 7f5a6a6f7b78ac9a72d6cd0e956aac21 375 SUPERFAMILY SSF53448 236 361 3.94E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS02290 7f5a6a6f7b78ac9a72d6cd0e956aac21 375 SUPERFAMILY SSF53448 41 175 3.94E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS02290 7f5a6a6f7b78ac9a72d6cd0e956aac21 375 Gene3D G3DSA:3.90.550.10 22 263 6.6E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CWR44_RS02290 7f5a6a6f7b78ac9a72d6cd0e956aac21 375 Pfam PF00535 Glycosyl transferase family 2 44 156 6.8E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CWR44_RS03230 c349a05ce3710176e1d5a74135d71a5d 288 Pfam PF00480 ROK family 4 285 4.1E-34 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CWR44_RS03230 c349a05ce3710176e1d5a74135d71a5d 288 SUPERFAMILY SSF53067 1 285 1.9E-43 T 28-03-2018 CWR44_RS03230 c349a05ce3710176e1d5a74135d71a5d 288 Gene3D G3DSA:3.30.420.40 122 286 1.7E-30 T 28-03-2018 CWR44_RS03230 c349a05ce3710176e1d5a74135d71a5d 288 Gene3D G3DSA:3.30.420.40 2 121 4.3E-14 T 28-03-2018 CWR44_RS08525 efbf45743376be0b09493e47f8f98a77 62 Gene3D G3DSA:2.30.170.40 2 61 3.1E-18 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08525 efbf45743376be0b09493e47f8f98a77 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.282 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08525 efbf45743376be0b09493e47f8f98a77 62 SUPERFAMILY SSF143800 1 60 3.34E-23 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS08525 efbf45743376be0b09493e47f8f98a77 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 5.0E-22 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS08525 efbf45743376be0b09493e47f8f98a77 62 Pfam PF00830 Ribosomal L28 family 3 58 1.9E-19 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS12205 5e1311f460366c8da458900c9aee34f8 578 Gene3D G3DSA:1.20.1560.10 1 323 9.4E-67 T 28-03-2018 CWR44_RS12205 5e1311f460366c8da458900c9aee34f8 578 SUPERFAMILY SSF90123 4 320 2.62E-79 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR44_RS12205 5e1311f460366c8da458900c9aee34f8 578 Gene3D G3DSA:3.40.50.300 328 578 3.6E-78 T 28-03-2018 CWR44_RS12205 5e1311f460366c8da458900c9aee34f8 578 Pfam PF00664 ABC transporter transmembrane region 17 294 9.1E-46 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CWR44_RS12205 5e1311f460366c8da458900c9aee34f8 578 SUPERFAMILY SSF52540 332 576 2.54E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS12205 5e1311f460366c8da458900c9aee34f8 578 Pfam PF00005 ABC transporter 357 506 9.5E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS12205 5e1311f460366c8da458900c9aee34f8 578 SMART SM00382 366 552 5.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS12205 5e1311f460366c8da458900c9aee34f8 578 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS02760 5b90cbea04398dda37b0c5a660d52454 220 Pfam PF13807 G-rich domain on putative tyrosine kinase 141 192 1.3E-6 T 28-03-2018 IPR032807 Tyrosine kinase, G-rich domain CWR44_RS02760 5b90cbea04398dda37b0c5a660d52454 220 Pfam PF02706 Chain length determinant protein 3 92 1.1E-24 T 28-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CWR44_RS02760 5b90cbea04398dda37b0c5a660d52454 220 Gene3D G3DSA:3.30.1890.10 37 148 5.2E-8 T 28-03-2018 CWR44_RS01390 fd23491e75786049da88cfbeec05f127 138 Pfam PF11070 Protein of unknown function (DUF2871) 1 130 3.2E-45 T 28-03-2018 IPR021299 Protein of unknown function DUF2871 CWR44_RS01390 fd23491e75786049da88cfbeec05f127 138 Gene3D G3DSA:1.20.210.10 1 138 0.001 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS03525 f8fab0e03b065024f3a9a53d7dc2dc03 552 SUPERFAMILY SSF51905 488 550 2.59E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03525 f8fab0e03b065024f3a9a53d7dc2dc03 552 SUPERFAMILY SSF51905 2 279 2.59E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS03525 f8fab0e03b065024f3a9a53d7dc2dc03 552 Pfam PF00890 FAD binding domain 7 533 4.0E-83 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CWR44_RS03525 f8fab0e03b065024f3a9a53d7dc2dc03 552 PIRSF PIRSF036654 1 551 8.4E-256 T 28-03-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 CWR44_RS03525 f8fab0e03b065024f3a9a53d7dc2dc03 552 Gene3D G3DSA:3.50.50.60 1 552 6.3E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS10875 06d0f950e1d5915e26ef2a6b59484388 241 SUPERFAMILY SSF53335 7 241 2.43E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS10875 06d0f950e1d5915e26ef2a6b59484388 241 Pfam PF13649 Methyltransferase domain 40 130 1.6E-16 T 28-03-2018 CWR44_RS10875 06d0f950e1d5915e26ef2a6b59484388 241 Gene3D G3DSA:3.40.50.150 2 135 9.5E-21 T 28-03-2018 CWR44_RS10875 06d0f950e1d5915e26ef2a6b59484388 241 Gene3D G3DSA:2.20.25.110 138 200 3.8E-15 T 28-03-2018 CWR44_RS03570 2a796f88e48191579fa9d1a1ac2399cc 566 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS03570 2a796f88e48191579fa9d1a1ac2399cc 566 Gene3D G3DSA:3.90.350.10 263 498 2.2E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS03570 2a796f88e48191579fa9d1a1ac2399cc 566 Pfam PF01609 Transposase DDE domain 264 515 8.8E-38 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS10020 8a11aa252c7cdd3415a25fc67ca3023f 208 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 8 197 7.5E-63 T 28-03-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein CWR44_RS10885 d48415b28ec497b72368d611f12db522 194 SUPERFAMILY SSF109604 4 161 3.4E-29 T 28-03-2018 CWR44_RS10885 d48415b28ec497b72368d611f12db522 194 Gene3D G3DSA:1.10.3210.10 1 189 4.9E-24 T 28-03-2018 CWR44_RS10885 d48415b28ec497b72368d611f12db522 194 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 182 6.7E-42 T 28-03-2018 IPR005249 Conserved hypothetical protein CHP00488 CWR44_RS10885 d48415b28ec497b72368d611f12db522 194 Pfam PF01966 HD domain 18 130 1.6E-12 T 28-03-2018 IPR006674 HD domain CWR44_RS10885 d48415b28ec497b72368d611f12db522 194 SMART SM00471 14 141 5.0E-7 T 28-03-2018 IPR003607 HD/PDEase domain CWR44_RS03520 f3574956c162f52b8c9151ce434fa7db 460 Gene3D G3DSA:3.40.605.10 1 248 3.3E-90 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS03520 f3574956c162f52b8c9151ce434fa7db 460 SUPERFAMILY SSF53720 4 457 1.7E-157 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR44_RS03520 f3574956c162f52b8c9151ce434fa7db 460 Pfam PF00171 Aldehyde dehydrogenase family 4 454 4.5E-162 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS03520 f3574956c162f52b8c9151ce434fa7db 460 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 258 269 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS03520 f3574956c162f52b8c9151ce434fa7db 460 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 230 237 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS03520 f3574956c162f52b8c9151ce434fa7db 460 Gene3D G3DSA:3.40.309.10 249 441 5.3E-66 T 28-03-2018 CWR44_RS01895 591ffd04bb0776ddbd175ce664fd1223 452 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 7 452 2.9E-184 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CWR44_RS01895 591ffd04bb0776ddbd175ce664fd1223 452 Pfam PF02447 GntP family permease 6 450 1.7E-172 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CWR44_RS01895 591ffd04bb0776ddbd175ce664fd1223 452 PIRSF PIRSF002746 2 452 8.1E-172 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 28-03-2018 IPR002178 PTS EIIA type-2 domain CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 188 270 4.1E-31 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 Pfam PF02378 Phosphotransferase system, EIIC 317 586 1.0E-16 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 Gene3D G3DSA:3.40.50.2300 185 281 5.3E-39 T 28-03-2018 CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 SUPERFAMILY SSF55804 1 148 5.36E-44 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 Gene3D G3DSA:3.40.930.10 1 162 4.1E-46 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 148 5.9E-42 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 SUPERFAMILY SSF52794 186 282 3.66E-36 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 300 641 8.4E-120 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 6.9E-40 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CWR44_RS06535 00766d5caaa2d891f2144257a4b09c45 657 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 188 277 9.6E-17 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CWR44_RS06440 9f348e6aec86dc9e6fc717e6ff62e12b 148 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 146 5.6E-39 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 CWR44_RS06440 9f348e6aec86dc9e6fc717e6ff62e12b 148 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 2 148 28.515 T 28-03-2018 IPR003791 Protein of unknown function UPF0178 CWR44_RS07775 0bf6077df1f32ee4b4ff1e364387ac66 299 SUPERFAMILY SSF53590 1 297 1.57E-85 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CWR44_RS07775 0bf6077df1f32ee4b4ff1e364387ac66 299 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 284 3.5E-78 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CWR44_RS07775 0bf6077df1f32ee4b4ff1e364387ac66 299 Gene3D G3DSA:3.90.245.10 2 299 6.2E-90 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CWR44_RS07480 1b51536fb67bf8112f5118a07a953605 359 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 2.4E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWR44_RS07480 1b51536fb67bf8112f5118a07a953605 359 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 299 3.1E-12 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWR44_RS07480 1b51536fb67bf8112f5118a07a953605 359 SUPERFAMILY SSF52540 5 255 1.49E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS07480 1b51536fb67bf8112f5118a07a953605 359 Gene3D G3DSA:3.40.50.300 2 336 2.2E-77 T 28-03-2018 CWR44_RS07480 1b51536fb67bf8112f5118a07a953605 359 SMART SM00382 34 242 1.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS07480 1b51536fb67bf8112f5118a07a953605 359 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS07480 1b51536fb67bf8112f5118a07a953605 359 Pfam PF00005 ABC transporter 26 184 2.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS06050 3de1fd3a6c5dce7918f0485dae707551 142 Gene3D G3DSA:2.40.128.20 1 142 2.1E-38 T 28-03-2018 IPR012674 Calycin CWR44_RS06050 3de1fd3a6c5dce7918f0485dae707551 142 SUPERFAMILY SSF50814 5 140 2.8E-41 T 28-03-2018 IPR012674 Calycin CWR44_RS06050 3de1fd3a6c5dce7918f0485dae707551 142 Pfam PF09148 Domain of unknown function (DUF1934) 14 135 3.7E-33 T 28-03-2018 IPR015231 Protein of unknown function DUF1934 CWR44_RS03085 2cfcb81b7437c65d9873486a92a2f6eb 238 Pfam PF11368 Protein of unknown function (DUF3169) 1 231 3.4E-33 T 28-03-2018 IPR021509 Protein of unknown function DUF3169 CWR44_RS12600 cb465e7f9307bd535abe138820b8060c 233 Pfam PF12686 Protein of unknown function (DUF3800) 8 207 3.5E-18 T 28-03-2018 IPR024524 Protein of unknown function DUF3800 CWR44_RS06415 6a60a697e16bcd1421829f78886837fd 149 Pfam PF00583 Acetyltransferase (GNAT) family 47 136 1.6E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS06415 6a60a697e16bcd1421829f78886837fd 149 Gene3D G3DSA:3.40.630.30 1 145 3.8E-14 T 28-03-2018 CWR44_RS06415 6a60a697e16bcd1421829f78886837fd 149 SUPERFAMILY SSF55729 3 142 7.03E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS04590 5715b726a88b71f209ca35d053d80a26 276 Gene3D G3DSA:1.10.10.730 108 155 2.7E-21 T 28-03-2018 CWR44_RS04590 5715b726a88b71f209ca35d053d80a26 276 SUPERFAMILY SSF110849 18 109 6.54E-27 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWR44_RS04590 5715b726a88b71f209ca35d053d80a26 276 SMART SM00470 18 107 3.1E-35 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWR44_RS04590 5715b726a88b71f209ca35d053d80a26 276 Gene3D G3DSA:3.90.1530.10 6 107 6.9E-36 T 28-03-2018 CWR44_RS04590 5715b726a88b71f209ca35d053d80a26 276 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 15 191 4.3E-58 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CWR44_RS04590 5715b726a88b71f209ca35d053d80a26 276 SUPERFAMILY SSF109709 99 210 1.36E-32 T 28-03-2018 CWR44_RS04590 5715b726a88b71f209ca35d053d80a26 276 Pfam PF02195 ParB-like nuclease domain 19 106 2.0E-26 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CWR44_RS10470 ba4ddc3caaa5c47a6b0f4c3ad4b181f1 331 Gene3D G3DSA:1.10.260.40 1 52 2.9E-18 T 28-03-2018 CWR44_RS10470 ba4ddc3caaa5c47a6b0f4c3ad4b181f1 331 SMART SM00354 1 68 8.5E-24 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS10470 ba4ddc3caaa5c47a6b0f4c3ad4b181f1 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 8.7E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CWR44_RS10470 ba4ddc3caaa5c47a6b0f4c3ad4b181f1 331 SUPERFAMILY SSF47413 1 56 6.38E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS10470 ba4ddc3caaa5c47a6b0f4c3ad4b181f1 331 Gene3D G3DSA:3.40.50.2300 53 176 4.1E-22 T 28-03-2018 CWR44_RS10470 ba4ddc3caaa5c47a6b0f4c3ad4b181f1 331 Gene3D G3DSA:3.40.50.2300 177 303 1.6E-18 T 28-03-2018 CWR44_RS10470 ba4ddc3caaa5c47a6b0f4c3ad4b181f1 331 SUPERFAMILY SSF53822 55 314 1.61E-43 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWR44_RS10470 ba4ddc3caaa5c47a6b0f4c3ad4b181f1 331 Pfam PF13377 Periplasmic binding protein-like domain 170 328 2.0E-19 T 28-03-2018 CWR44_RS03600 d6072e033bd2abd27638079ef60a2368 393 Pfam PF04235 Protein of unknown function (DUF418) 234 386 3.6E-32 T 28-03-2018 IPR007349 Domain of unknown function DUF418 CWR44_RS01185 779aebfa601def9e0b88f49518c33ea4 217 Gene3D G3DSA:2.40.33.20 1 217 3.0E-36 T 28-03-2018 CWR44_RS01185 779aebfa601def9e0b88f49518c33ea4 217 Pfam PF03473 MOSC domain 51 160 5.2E-15 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CWR44_RS01185 779aebfa601def9e0b88f49518c33ea4 217 SUPERFAMILY SSF50800 1 214 4.08E-63 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CWR44_RS07155 d382c6b2fd01179eee32abbe0a1add50 153 SUPERFAMILY SSF82649 3 138 7.12E-51 T 28-03-2018 CWR44_RS07155 d382c6b2fd01179eee32abbe0a1add50 153 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 138 1.4E-54 T 28-03-2018 CWR44_RS07155 d382c6b2fd01179eee32abbe0a1add50 153 Gene3D G3DSA:3.90.1010.10 3 140 3.5E-52 T 28-03-2018 CWR44_RS07155 d382c6b2fd01179eee32abbe0a1add50 153 Pfam PF01592 NifU-like N terminal domain 10 128 2.9E-33 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CWR44_RS07265 3e8b9a6b5638d25f0369be37b6dca134 119 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 4 108 7.1E-34 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CWR44_RS07265 3e8b9a6b5638d25f0369be37b6dca134 119 SUPERFAMILY SSF89360 3 97 2.35E-27 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CWR44_RS07265 3e8b9a6b5638d25f0369be37b6dca134 119 Pfam PF01521 Iron-sulphur cluster biosynthesis 4 104 4.0E-19 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CWR44_RS07265 3e8b9a6b5638d25f0369be37b6dca134 119 Gene3D G3DSA:2.60.300.12 3 112 2.0E-35 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CWR44_RS07265 3e8b9a6b5638d25f0369be37b6dca134 119 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 90 107 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CWR44_RS01820 31f8b6efbbb39195c1cc551fdfb5bbc9 428 Gene3D G3DSA:3.90.1150.10 294 428 5.2E-50 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS01820 31f8b6efbbb39195c1cc551fdfb5bbc9 428 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 425 4.0E-144 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS01820 31f8b6efbbb39195c1cc551fdfb5bbc9 428 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 203 217 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS01820 31f8b6efbbb39195c1cc551fdfb5bbc9 428 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 9 425 2.6E-202 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CWR44_RS01820 31f8b6efbbb39195c1cc551fdfb5bbc9 428 Gene3D G3DSA:3.40.640.10 8 292 9.5E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS01820 31f8b6efbbb39195c1cc551fdfb5bbc9 428 PIRSF PIRSF001434 1 428 3.0E-133 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CWR44_RS01820 31f8b6efbbb39195c1cc551fdfb5bbc9 428 SUPERFAMILY SSF53383 8 425 2.82E-128 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS03975 bedac04424e6a55093af872ccdc3dd36 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.8E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03975 bedac04424e6a55093af872ccdc3dd36 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 40 2.8E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03975 bedac04424e6a55093af872ccdc3dd36 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 2.8E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03975 bedac04424e6a55093af872ccdc3dd36 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 2.8E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03975 bedac04424e6a55093af872ccdc3dd36 104 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 1.2E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03975 bedac04424e6a55093af872ccdc3dd36 104 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 31 49 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CWR44_RS03975 bedac04424e6a55093af872ccdc3dd36 104 SUPERFAMILY SSF46785 3 82 7.53E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03975 bedac04424e6a55093af872ccdc3dd36 104 SMART SM00418 8 85 4.5E-26 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CWR44_RS03975 bedac04424e6a55093af872ccdc3dd36 104 Gene3D G3DSA:1.10.10.10 1 81 5.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS07810 692d5363f6a883ff9ed6c818fa644aa0 559 Pfam PF01609 Transposase DDE domain 264 515 1.1E-37 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS07810 692d5363f6a883ff9ed6c818fa644aa0 559 Gene3D G3DSA:3.90.350.10 280 498 2.8E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS07810 692d5363f6a883ff9ed6c818fa644aa0 559 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS04690 1069e14483b9aa4ef2ab8c566c26fe09 172 SUPERFAMILY SSF52317 1 170 1.33E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS04690 1069e14483b9aa4ef2ab8c566c26fe09 172 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 171 3.4E-47 T 28-03-2018 IPR006286 Peptidase C56, PfpI CWR44_RS04690 1069e14483b9aa4ef2ab8c566c26fe09 172 Gene3D G3DSA:3.40.50.880 1 172 1.7E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS04690 1069e14483b9aa4ef2ab8c566c26fe09 172 Pfam PF01965 DJ-1/PfpI family 3 169 3.0E-53 T 28-03-2018 IPR002818 DJ-1/PfpI CWR44_RS11285 d7102d1811eed6afc559a2ec20a8efb5 306 Pfam PF07319 Primosomal protein DnaI N-terminus 1 94 2.6E-26 T 28-03-2018 IPR009928 Primosomal DnaI, N-terminal CWR44_RS11285 d7102d1811eed6afc559a2ec20a8efb5 306 SUPERFAMILY SSF52540 125 270 7.08E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS11285 d7102d1811eed6afc559a2ec20a8efb5 306 Pfam PF01695 IstB-like ATP binding protein 128 270 9.8E-11 T 28-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CWR44_RS11285 d7102d1811eed6afc559a2ec20a8efb5 306 Gene3D G3DSA:3.40.50.300 2 296 3.3E-15 T 28-03-2018 CWR44_RS09805 f68752a8f51ecfbc7036867e68f3760e 485 Pfam PF01235 Sodium:alanine symporter family 66 461 8.3E-163 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR44_RS09805 f68752a8f51ecfbc7036867e68f3760e 485 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 101 116 - T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR44_RS09805 f68752a8f51ecfbc7036867e68f3760e 485 PRINTS PR00175 Sodium/alanine symporter signature 220 239 1.3E-59 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR44_RS09805 f68752a8f51ecfbc7036867e68f3760e 485 PRINTS PR00175 Sodium/alanine symporter signature 311 329 1.3E-59 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR44_RS09805 f68752a8f51ecfbc7036867e68f3760e 485 PRINTS PR00175 Sodium/alanine symporter signature 358 380 1.3E-59 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR44_RS09805 f68752a8f51ecfbc7036867e68f3760e 485 PRINTS PR00175 Sodium/alanine symporter signature 101 123 1.3E-59 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR44_RS09805 f68752a8f51ecfbc7036867e68f3760e 485 PRINTS PR00175 Sodium/alanine symporter signature 418 438 1.3E-59 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR44_RS09805 f68752a8f51ecfbc7036867e68f3760e 485 PRINTS PR00175 Sodium/alanine symporter signature 192 210 1.3E-59 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR44_RS09805 f68752a8f51ecfbc7036867e68f3760e 485 TIGRFAM TIGR00835 agcS: amino acid carrier protein 24 449 2.0E-154 T 28-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CWR44_RS05990 6b9c8ce2a39733cfe1c5fc78fb91fc09 432 SUPERFAMILY SSF109604 9 412 3.14E-109 T 28-03-2018 CWR44_RS05990 6b9c8ce2a39733cfe1c5fc78fb91fc09 432 Pfam PF01966 HD domain 64 184 3.6E-15 T 28-03-2018 IPR006674 HD domain CWR44_RS05990 6b9c8ce2a39733cfe1c5fc78fb91fc09 432 SMART SM00471 60 190 4.2E-11 T 28-03-2018 IPR003607 HD/PDEase domain CWR44_RS05990 6b9c8ce2a39733cfe1c5fc78fb91fc09 432 Gene3D G3DSA:1.10.3210.10 13 315 1.8E-76 T 28-03-2018 CWR44_RS04885 37d9f0568872304cf34e024ba7ddeb4e 462 Pfam PF00375 Sodium:dicarboxylate symporter family 32 441 1.3E-98 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS04885 37d9f0568872304cf34e024ba7ddeb4e 462 SUPERFAMILY SSF118215 31 441 1.57E-87 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS04885 37d9f0568872304cf34e024ba7ddeb4e 462 PRINTS PR00173 Glutamate-aspartate symporter signature 233 252 1.7E-18 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS04885 37d9f0568872304cf34e024ba7ddeb4e 462 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 1.7E-18 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS04885 37d9f0568872304cf34e024ba7ddeb4e 462 PRINTS PR00173 Glutamate-aspartate symporter signature 396 416 1.7E-18 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS04885 37d9f0568872304cf34e024ba7ddeb4e 462 PRINTS PR00173 Glutamate-aspartate symporter signature 369 388 1.7E-18 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS04885 37d9f0568872304cf34e024ba7ddeb4e 462 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 1.7E-18 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS04885 37d9f0568872304cf34e024ba7ddeb4e 462 Gene3D G3DSA:1.10.3860.10 19 449 8.2E-87 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CWR44_RS08620 a07b3a1aa30035639c0cdc88b2abd62c 869 Pfam PF09586 Bacterial membrane protein YfhO 24 851 7.8E-139 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO CWR44_RS02000 8c781b325ed241621394366d941b4b57 322 SUPERFAMILY SSF54593 4 302 1.45E-46 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS02000 8c781b325ed241621394366d941b4b57 322 Gene3D G3DSA:3.10.180.10 1 158 3.2E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS02000 8c781b325ed241621394366d941b4b57 322 Gene3D G3DSA:3.10.180.10 159 319 5.6E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS02000 8c781b325ed241621394366d941b4b57 322 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 265 2.6E-22 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWR44_RS06705 7753160e4ff27ae7a8c6577fa1f0f03b 319 SUPERFAMILY SSF81345 8 314 1.12E-54 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWR44_RS06705 7753160e4ff27ae7a8c6577fa1f0f03b 319 Gene3D G3DSA:1.10.3470.10 28 319 6.6E-33 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS06705 7753160e4ff27ae7a8c6577fa1f0f03b 319 Pfam PF01032 FecCD transport family 9 314 8.2E-52 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR44_RS02720 288d69ae207b33ab7feefa942ae144ad 371 Gene3D G3DSA:3.40.50.2000 36 196 6.8E-6 T 28-03-2018 CWR44_RS02720 288d69ae207b33ab7feefa942ae144ad 371 SUPERFAMILY SSF53756 63 369 8.38E-29 T 28-03-2018 CWR44_RS02720 288d69ae207b33ab7feefa942ae144ad 371 Pfam PF13692 Glycosyl transferases group 1 194 336 4.0E-9 T 28-03-2018 CWR44_RS02720 288d69ae207b33ab7feefa942ae144ad 371 Pfam PF13439 Glycosyltransferase Family 4 61 177 3.5E-10 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CWR44_RS02720 288d69ae207b33ab7feefa942ae144ad 371 Gene3D G3DSA:3.40.50.2000 197 361 4.0E-17 T 28-03-2018 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 PIRSF PIRSF000732 1 571 7.6E-224 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 SUPERFAMILY SSF52009 126 248 1.44E-36 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 SUPERFAMILY SSF47831 24 144 2.48E-37 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 127 2.2E-33 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 SUPERFAMILY SSF51621 251 550 2.88E-112 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 Gene3D G3DSA:3.20.20.60 256 571 2.0E-103 T 28-03-2018 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 567 7.3E-248 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 448 463 5.8E-32 T 28-03-2018 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 294 313 5.8E-32 T 28-03-2018 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 465 480 5.8E-32 T 28-03-2018 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 501 513 5.8E-32 T 28-03-2018 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 226 5.0E-23 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 Gene3D G3DSA:1.10.274.10 26 136 1.5E-38 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 251 539 1.6E-129 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 448 466 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 185 196 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CWR44_RS07920 0cfcef66c9b764499a3af2a3c55da614 571 Gene3D G3DSA:3.50.30.10 137 255 9.9E-30 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CWR44_RS12630 f22155882d602fb69bf97484482db46b 207 Gene3D G3DSA:3.40.109.10 11 203 3.5E-21 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR44_RS12630 f22155882d602fb69bf97484482db46b 207 SUPERFAMILY SSF55469 11 204 5.37E-64 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR44_RS12630 f22155882d602fb69bf97484482db46b 207 Pfam PF00881 Nitroreductase family 16 185 6.9E-11 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR44_RS02615 4d93e877d532b663d838a98ef01aeff2 254 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 236 2.1E-92 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR44_RS02615 4d93e877d532b663d838a98ef01aeff2 254 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 213 1.1E-50 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS02615 4d93e877d532b663d838a98ef01aeff2 254 SUPERFAMILY SSF53790 1 244 8.11E-79 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS02615 4d93e877d532b663d838a98ef01aeff2 254 Gene3D G3DSA:3.30.950.10 127 252 1.1E-39 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS02615 4d93e877d532b663d838a98ef01aeff2 254 Gene3D G3DSA:3.40.1010.10 1 126 1.1E-36 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CWR44_RS02615 4d93e877d532b663d838a98ef01aeff2 254 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CWR44_RS03680 b9c3dedb30c18214eb1569ae3cc59ce6 305 Pfam PF13407 Periplasmic binding protein domain 41 287 6.0E-64 T 28-03-2018 IPR025997 Periplasmic binding protein CWR44_RS03680 b9c3dedb30c18214eb1569ae3cc59ce6 305 Gene3D G3DSA:3.40.50.2300 33 152 3.5E-31 T 28-03-2018 CWR44_RS03680 b9c3dedb30c18214eb1569ae3cc59ce6 305 Gene3D G3DSA:3.40.50.2300 153 301 1.1E-39 T 28-03-2018 CWR44_RS03680 b9c3dedb30c18214eb1569ae3cc59ce6 305 SUPERFAMILY SSF53822 34 302 1.16E-84 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CWR44_RS01755 04cfdc355196eb60d247208b5c1466d8 347 SUPERFAMILY SSF51735 142 310 2.75E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS01755 04cfdc355196eb60d247208b5c1466d8 347 Gene3D G3DSA:3.90.180.10 1 151 2.4E-40 T 28-03-2018 CWR44_RS01755 04cfdc355196eb60d247208b5c1466d8 347 Gene3D G3DSA:3.40.50.720 152 334 1.7E-33 T 28-03-2018 CWR44_RS01755 04cfdc355196eb60d247208b5c1466d8 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CWR44_RS01755 04cfdc355196eb60d247208b5c1466d8 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 137 2.9E-24 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CWR44_RS01755 04cfdc355196eb60d247208b5c1466d8 347 SUPERFAMILY SSF50129 1 177 2.74E-44 T 28-03-2018 IPR011032 GroES-like CWR44_RS01755 04cfdc355196eb60d247208b5c1466d8 347 SMART SM00829 8 343 2.0E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR44_RS01755 04cfdc355196eb60d247208b5c1466d8 347 Pfam PF00107 Zinc-binding dehydrogenase 178 305 2.5E-30 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR44_RS00410 ced7dfbaf7d4db0f54669ed94427470c 268 Gene3D G3DSA:3.40.1700.10 115 243 2.4E-37 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWR44_RS00410 ced7dfbaf7d4db0f54669ed94427470c 268 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 7 256 1.3E-88 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CWR44_RS00410 ced7dfbaf7d4db0f54669ed94427470c 268 SUPERFAMILY SSF143597 44 244 2.62E-68 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWR44_RS00410 ced7dfbaf7d4db0f54669ed94427470c 268 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 122 240 1.0E-44 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CWR44_RS00410 ced7dfbaf7d4db0f54669ed94427470c 268 PIRSF PIRSF004793 6 265 8.4E-92 T 28-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CWR44_RS00410 ced7dfbaf7d4db0f54669ed94427470c 268 Hamap MF_01499 Diadenylate cyclase [dacA]. 8 258 32.416 T 28-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CWR44_RS12350 4830fe31081bac9c6b449093136b47e3 166 Gene3D G3DSA:1.20.1260.10 1 162 3.6E-44 T 28-03-2018 IPR012347 Ferritin-related CWR44_RS12350 4830fe31081bac9c6b449093136b47e3 166 SUPERFAMILY SSF47240 1 159 5.99E-56 T 28-03-2018 IPR009078 Ferritin-like superfamily CWR44_RS12350 4830fe31081bac9c6b449093136b47e3 166 Pfam PF00210 Ferritin-like domain 8 144 9.3E-42 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CWR44_RS01400 778511d5c4ea87d5f98316a63a2939e9 415 Gene3D G3DSA:2.60.40.1220 32 128 4.1E-20 T 28-03-2018 CWR44_RS01400 778511d5c4ea87d5f98316a63a2939e9 415 Pfam PF04234 CopC domain 33 127 1.3E-18 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CWR44_RS01400 778511d5c4ea87d5f98316a63a2939e9 415 SUPERFAMILY SSF81296 32 128 7.7E-20 T 28-03-2018 IPR014756 Immunoglobulin E-set CWR44_RS07290 213fe778aa63dfabf96ee1a6efe97d4f 388 SUPERFAMILY SSF51905 182 313 9.54E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07290 213fe778aa63dfabf96ee1a6efe97d4f 388 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 47 257 8.2E-12 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CWR44_RS07290 213fe778aa63dfabf96ee1a6efe97d4f 388 Gene3D G3DSA:3.50.50.60 3 195 1.1E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07290 213fe778aa63dfabf96ee1a6efe97d4f 388 SUPERFAMILY SSF51905 3 228 4.53E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS07290 213fe778aa63dfabf96ee1a6efe97d4f 388 Gene3D G3DSA:3.50.50.60 196 379 4.3E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11950 0c212bb608ea0ef42b5886e419068ff5 114 SUPERFAMILY SSF158622 3 113 9.03E-36 T 28-03-2018 IPR023378 YheA/YmcA-like domain CWR44_RS11950 0c212bb608ea0ef42b5886e419068ff5 114 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 6 108 2.7E-24 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CWR44_RS11950 0c212bb608ea0ef42b5886e419068ff5 114 Gene3D G3DSA:1.20.1500.10 4 109 5.7E-28 T 28-03-2018 IPR023378 YheA/YmcA-like domain CWR44_RS11950 0c212bb608ea0ef42b5886e419068ff5 114 Hamap MF_01526 UPF0342 protein . 2 113 19.221 T 28-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CWR44_RS08405 f119675f61eecfd7ebbb6f811b66906e 436 Pfam PF00860 Permease family 25 397 5.8E-109 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR44_RS08405 f119675f61eecfd7ebbb6f811b66906e 436 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 346 366 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWR44_RS08405 f119675f61eecfd7ebbb6f811b66906e 436 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 21 426 3.3E-131 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CWR44_RS07975 7a1f311afe2c6d1ff1e13142ae1a92b6 183 Hamap MF_00163 Peptide deformylase [def]. 3 183 27.58 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS07975 7a1f311afe2c6d1ff1e13142ae1a92b6 183 PIRSF PIRSF004749 2 178 3.1E-46 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS07975 7a1f311afe2c6d1ff1e13142ae1a92b6 183 Pfam PF01327 Polypeptide deformylase 4 171 1.9E-44 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS07975 7a1f311afe2c6d1ff1e13142ae1a92b6 183 PRINTS PR01576 Peptide deformylase signature 47 76 4.0E-31 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS07975 7a1f311afe2c6d1ff1e13142ae1a92b6 183 PRINTS PR01576 Peptide deformylase signature 109 120 4.0E-31 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS07975 7a1f311afe2c6d1ff1e13142ae1a92b6 183 PRINTS PR01576 Peptide deformylase signature 141 170 4.0E-31 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS07975 7a1f311afe2c6d1ff1e13142ae1a92b6 183 PRINTS PR01576 Peptide deformylase signature 122 140 4.0E-31 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS07975 7a1f311afe2c6d1ff1e13142ae1a92b6 183 SUPERFAMILY SSF56420 2 179 5.1E-61 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS07975 7a1f311afe2c6d1ff1e13142ae1a92b6 183 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 174 5.0E-45 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS07975 7a1f311afe2c6d1ff1e13142ae1a92b6 183 Gene3D G3DSA:3.90.45.10 3 178 9.4E-53 T 28-03-2018 IPR023635 Peptide deformylase CWR44_RS05235 734e986551ee2b3aca01140868403644 446 Gene3D G3DSA:3.90.1150.10 253 365 3.4E-10 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS05235 734e986551ee2b3aca01140868403644 446 SUPERFAMILY SSF53383 4 338 6.77E-52 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS05235 734e986551ee2b3aca01140868403644 446 SUPERFAMILY SSF55904 308 439 1.22E-19 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CWR44_RS05235 734e986551ee2b3aca01140868403644 446 Gene3D G3DSA:3.90.100.10 366 446 1.1E-15 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CWR44_RS05235 734e986551ee2b3aca01140868403644 446 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 4 259 5.1E-40 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CWR44_RS05235 734e986551ee2b3aca01140868403644 446 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 380 428 3.5E-6 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CWR44_RS05235 734e986551ee2b3aca01140868403644 446 Gene3D G3DSA:3.40.640.10 34 252 4.2E-25 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS07990 2e861485a9a9085f9fce30b0a2da4057 325 SUPERFAMILY SSF52922 188 324 6.94E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR44_RS07990 2e861485a9a9085f9fce30b0a2da4057 325 SUPERFAMILY SSF52518 2 204 1.41E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS07990 2e861485a9a9085f9fce30b0a2da4057 325 Gene3D G3DSA:3.40.50.920 195 324 1.3E-36 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CWR44_RS07990 2e861485a9a9085f9fce30b0a2da4057 325 SMART SM00861 4 179 7.8E-55 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR44_RS07990 2e861485a9a9085f9fce30b0a2da4057 325 Gene3D G3DSA:3.40.50.970 1 194 6.6E-61 T 28-03-2018 CWR44_RS07990 2e861485a9a9085f9fce30b0a2da4057 325 Pfam PF02780 Transketolase, C-terminal domain 194 315 2.5E-39 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CWR44_RS07990 2e861485a9a9085f9fce30b0a2da4057 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 7.7E-37 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CWR44_RS03610 f0e705863bd052629435e75e2513b278 288 Gene3D G3DSA:3.40.190.10 1 215 3.9E-5 T 28-03-2018 CWR44_RS06465 3fc1d1938cca299e50f8b8830df59a2c 145 Pfam PF01047 MarR family 36 94 3.9E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS06465 3fc1d1938cca299e50f8b8830df59a2c 145 SMART SM00347 29 127 1.5E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CWR44_RS06465 3fc1d1938cca299e50f8b8830df59a2c 145 Gene3D G3DSA:1.10.10.10 2 141 6.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06465 3fc1d1938cca299e50f8b8830df59a2c 145 SUPERFAMILY SSF46785 6 139 2.59E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06465 3fc1d1938cca299e50f8b8830df59a2c 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CWR44_RS08945 087c05208388bee67f217a2e5eadd707 412 Pfam PF06838 Methionine gamma-lyase 5 404 1.4E-198 T 28-03-2018 IPR009651 Putative methionine gamma-lyase CWR44_RS08945 087c05208388bee67f217a2e5eadd707 412 Gene3D G3DSA:3.40.640.10 51 263 5.3E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS08945 087c05208388bee67f217a2e5eadd707 412 SUPERFAMILY SSF53383 42 390 7.29E-43 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 Pfam PF13177 DNA polymerase III, delta subunit 20 177 1.0E-47 T 28-03-2018 CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 Gene3D G3DSA:1.20.272.10 243 353 1.2E-11 T 28-03-2018 CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 303 8.7E-6 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 Gene3D G3DSA:3.40.50.300 1 166 6.6E-42 T 28-03-2018 CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 SMART SM00382 37 184 4.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 SUPERFAMILY SSF52540 33 222 9.73E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 346 7.0E-138 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 6.6E-6 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 6.6E-6 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 SUPERFAMILY SSF48019 244 351 1.28E-10 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CWR44_RS05200 d788591651ff42af0698b74d6443e0f9 571 Gene3D G3DSA:1.10.8.60 167 242 6.6E-19 T 28-03-2018 CWR44_RS07060 6c2fa6f7b08ad0fcfd1ed3c2c7b22f19 163 Pfam PF13420 Acetyltransferase (GNAT) domain 4 157 3.0E-25 T 28-03-2018 CWR44_RS07060 6c2fa6f7b08ad0fcfd1ed3c2c7b22f19 163 Gene3D G3DSA:3.40.630.30 1 163 4.8E-15 T 28-03-2018 CWR44_RS07060 6c2fa6f7b08ad0fcfd1ed3c2c7b22f19 163 SUPERFAMILY SSF55729 2 159 3.11E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS06400 d895a8ded2775e75f0fea6b425c07ae3 406 Gene3D G3DSA:1.20.1250.20 205 399 1.1E-22 T 28-03-2018 CWR44_RS06400 d895a8ded2775e75f0fea6b425c07ae3 406 Gene3D G3DSA:1.20.1250.20 2 202 5.3E-18 T 28-03-2018 CWR44_RS06400 d895a8ded2775e75f0fea6b425c07ae3 406 SUPERFAMILY SSF103473 11 395 1.44E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS06400 d895a8ded2775e75f0fea6b425c07ae3 406 Pfam PF07690 Major Facilitator Superfamily 17 247 5.6E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS01885 401cabf425d9382c38bf6e4f4b3744ec 131 Pfam PF00293 NUDIX domain 7 118 1.1E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR44_RS01885 401cabf425d9382c38bf6e4f4b3744ec 131 Gene3D G3DSA:3.90.79.10 1 131 5.4E-27 T 28-03-2018 CWR44_RS01885 401cabf425d9382c38bf6e4f4b3744ec 131 SUPERFAMILY SSF55811 1 126 8.67E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR44_RS00100 515e3158141cab5dd3f6cc681121908e 273 SUPERFAMILY SSF53613 5 266 8.57E-79 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS00100 515e3158141cab5dd3f6cc681121908e 273 Pfam PF08543 Phosphomethylpyrimidine kinase 14 260 1.5E-94 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CWR44_RS00100 515e3158141cab5dd3f6cc681121908e 273 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 262 1.9E-94 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS00100 515e3158141cab5dd3f6cc681121908e 273 Gene3D G3DSA:3.40.1190.20 1 271 2.3E-59 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS02950 f94d5bb3f596c6f1a64fe84ab4fa6749 158 SUPERFAMILY SSF55068 1 150 1.06E-42 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS02950 f94d5bb3f596c6f1a64fe84ab4fa6749 158 Pfam PF01625 Peptide methionine sulfoxide reductase 3 148 6.2E-38 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS02950 f94d5bb3f596c6f1a64fe84ab4fa6749 158 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 151 23.554 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS02950 f94d5bb3f596c6f1a64fe84ab4fa6749 158 Gene3D G3DSA:3.30.1060.10 1 158 8.6E-37 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CWR44_RS00390 88fa14141748729d8cd675855fa405b0 260 Pfam PF00005 ABC transporter 18 170 1.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS00390 88fa14141748729d8cd675855fa405b0 260 SUPERFAMILY SSF52540 2 235 4.61E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00390 88fa14141748729d8cd675855fa405b0 260 Gene3D G3DSA:3.40.50.300 1 253 6.1E-48 T 28-03-2018 CWR44_RS00390 88fa14141748729d8cd675855fa405b0 260 SMART SM00382 27 221 2.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS11900 1287dbd41def515e91a14656f1aff6e4 166 SUPERFAMILY SSF54909 70 139 2.52E-7 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CWR44_RS11900 1287dbd41def515e91a14656f1aff6e4 166 Gene3D G3DSA:3.30.70.100 69 160 1.0E-7 T 28-03-2018 CWR44_RS04530 7ee16f490d90b8aa9b0ccb59e81b7e42 357 Gene3D G3DSA:2.130.10.10 27 308 2.0E-5 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CWR44_RS04530 7ee16f490d90b8aa9b0ccb59e81b7e42 357 Gene3D G3DSA:2.20.28.20 2 26 1.2E-4 T 28-03-2018 CWR44_RS04530 7ee16f490d90b8aa9b0ccb59e81b7e42 357 Pfam PF13240 zinc-ribbon domain 3 24 1.6E-6 T 28-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CWR44_RS00920 cb5f0b82c3dfb739ae6be2368206e22d 334 Pfam PF00899 ThiF family 6 240 8.1E-50 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CWR44_RS00920 cb5f0b82c3dfb739ae6be2368206e22d 334 Gene3D G3DSA:3.40.50.720 1 244 2.1E-54 T 28-03-2018 CWR44_RS00920 cb5f0b82c3dfb739ae6be2368206e22d 334 SUPERFAMILY SSF69572 4 320 1.44E-76 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CWR44_RS00895 615bf7811645716c862907c3ec42f0d0 149 SUPERFAMILY SSF54690 4 139 5.62E-45 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CWR44_RS00895 615bf7811645716c862907c3ec42f0d0 149 Pfam PF02391 MoaE protein 7 117 1.8E-35 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CWR44_RS00895 615bf7811645716c862907c3ec42f0d0 149 Gene3D G3DSA:3.90.1170.40 1 148 1.4E-47 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CWR44_RS13160 142393a8cff8e2889a173fc0841d3467 91 SUPERFAMILY SSF52833 6 76 5.19E-12 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS13160 142393a8cff8e2889a173fc0841d3467 91 Gene3D G3DSA:3.40.30.10 1 85 6.6E-13 T 28-03-2018 CWR44_RS13160 142393a8cff8e2889a173fc0841d3467 91 Pfam PF00462 Glutaredoxin 8 57 1.3E-10 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CWR44_RS12220 ca1509c1bf6312752df5f64678cf4b31 325 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 152 1.1E-25 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CWR44_RS10320 196c64284ebd078b752fdb502209ee3d 195 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 55 149 1.0E-7 T 28-03-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 CWR44_RS07130 8cb39b1254b946ceb8a8eeb01067c45b 560 Gene3D G3DSA:3.90.350.10 262 498 2.1E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS07130 8cb39b1254b946ceb8a8eeb01067c45b 560 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS07130 8cb39b1254b946ceb8a8eeb01067c45b 560 Pfam PF01609 Transposase DDE domain 264 515 8.6E-38 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS06175 6c962be263cfbc1a8cf1cfa6d0eac2da 171 Pfam PF03334 Na+/H+ antiporter subunit 15 96 5.2E-23 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CWR44_RS06175 6c962be263cfbc1a8cf1cfa6d0eac2da 171 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 15 103 3.5E-24 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CWR44_RS01770 45761f6bfd646780a0d06616653e31ab 449 Gene3D G3DSA:3.40.50.1820 1 445 2.0E-81 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS01770 45761f6bfd646780a0d06616653e31ab 449 Pfam PF00135 Carboxylesterase family 3 432 9.2E-71 T 28-03-2018 IPR002018 Carboxylesterase, type B CWR44_RS01770 45761f6bfd646780a0d06616653e31ab 449 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 177 192 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CWR44_RS01770 45761f6bfd646780a0d06616653e31ab 449 SUPERFAMILY SSF53474 3 445 1.31E-86 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS05045 18868a0dd5ac56a22562fbaa607ce534 119 Pfam PF06993 Protein of unknown function (DUF1304) 11 117 1.9E-29 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 CWR44_RS02165 e84a26a253e19d07acbce0f1fb8b46b8 579 SUPERFAMILY SSF52518 359 540 1.12E-56 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS02165 e84a26a253e19d07acbce0f1fb8b46b8 579 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 3.6E-39 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CWR44_RS02165 e84a26a253e19d07acbce0f1fb8b46b8 579 SUPERFAMILY SSF52518 3 174 4.53E-41 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS02165 e84a26a253e19d07acbce0f1fb8b46b8 579 Gene3D G3DSA:3.40.50.970 1 189 4.3E-41 T 28-03-2018 CWR44_RS02165 e84a26a253e19d07acbce0f1fb8b46b8 579 Gene3D G3DSA:3.40.50.1220 190 345 6.2E-35 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS02165 e84a26a253e19d07acbce0f1fb8b46b8 579 SUPERFAMILY SSF52467 185 355 1.45E-44 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CWR44_RS02165 e84a26a253e19d07acbce0f1fb8b46b8 579 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 382 528 8.4E-38 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CWR44_RS02165 e84a26a253e19d07acbce0f1fb8b46b8 579 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CWR44_RS02165 e84a26a253e19d07acbce0f1fb8b46b8 579 Gene3D G3DSA:3.40.50.970 346 544 8.7E-37 T 28-03-2018 CWR44_RS02165 e84a26a253e19d07acbce0f1fb8b46b8 579 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 322 1.1E-33 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CWR44_RS09910 9a220e3c1cedb7a596531ee2caaa5006 338 Gene3D G3DSA:3.40.50.1980 23 178 8.0E-29 T 28-03-2018 CWR44_RS09910 9a220e3c1cedb7a596531ee2caaa5006 338 Gene3D G3DSA:3.40.50.1980 179 338 8.2E-29 T 28-03-2018 CWR44_RS09910 9a220e3c1cedb7a596531ee2caaa5006 338 SUPERFAMILY SSF53807 56 329 2.55E-50 T 28-03-2018 CWR44_RS09910 9a220e3c1cedb7a596531ee2caaa5006 338 Pfam PF01497 Periplasmic binding protein 71 311 4.9E-31 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CWR44_RS07075 685aca653cdea15b3c6c604ff6a3fa90 241 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 21 233 2.4E-55 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CWR44_RS07075 685aca653cdea15b3c6c604ff6a3fa90 241 Gene3D G3DSA:3.20.20.70 3 237 4.3E-60 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS07075 685aca653cdea15b3c6c604ff6a3fa90 241 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 5 238 31.724 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CWR44_RS07075 685aca653cdea15b3c6c604ff6a3fa90 241 Pfam PF01487 Type I 3-dehydroquinase 20 234 8.7E-52 T 28-03-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CWR44_RS07075 685aca653cdea15b3c6c604ff6a3fa90 241 SUPERFAMILY SSF51569 20 235 4.39E-62 T 28-03-2018 CWR44_RS08315 6a855af13dc60da3d0708ae6d33668db 321 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 1 320 23.715 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR44_RS08315 6a855af13dc60da3d0708ae6d33668db 321 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 14 316 5.0E-103 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR44_RS08315 6a855af13dc60da3d0708ae6d33668db 321 Pfam PF00953 Glycosyl transferase family 4 77 246 2.7E-39 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CWR44_RS08315 6a855af13dc60da3d0708ae6d33668db 321 ProSitePatterns PS01347 MraY family signature 1. 44 56 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR44_RS08315 6a855af13dc60da3d0708ae6d33668db 321 ProSitePatterns PS01348 MraY family signature 2. 166 177 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CWR44_RS05290 c97cf2d192f7b32899d591911135765d 182 SUPERFAMILY SSF110455 1 114 9.42E-36 T 28-03-2018 CWR44_RS05290 c97cf2d192f7b32899d591911135765d 182 SMART SM00493 4 77 1.9E-5 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS05290 c97cf2d192f7b32899d591911135765d 182 Pfam PF13331 Domain of unknown function (DUF4093) 91 175 1.4E-26 T 28-03-2018 IPR025156 Ribonuclease M5, C-terminal domain CWR44_RS05290 c97cf2d192f7b32899d591911135765d 182 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 177 30.1 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CWR44_RS05290 c97cf2d192f7b32899d591911135765d 182 Pfam PF01751 Toprim domain 6 73 4.1E-5 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS05290 c97cf2d192f7b32899d591911135765d 182 Gene3D G3DSA:3.40.1360.20 1 124 1.2E-19 T 28-03-2018 CWR44_RS05290 c97cf2d192f7b32899d591911135765d 182 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 175 5.0E-55 T 28-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CWR44_RS09385 c7de4a15cb30d0003ea6b93c64e6ab18 341 SUPERFAMILY SSF55797 216 339 1.43E-24 T 28-03-2018 IPR014044 CAP domain CWR44_RS09385 c7de4a15cb30d0003ea6b93c64e6ab18 341 Pfam PF00188 Cysteine-rich secretory protein family 224 339 2.9E-14 T 28-03-2018 IPR014044 CAP domain CWR44_RS09385 c7de4a15cb30d0003ea6b93c64e6ab18 341 Gene3D G3DSA:3.30.1450.10 59 128 1.6E-9 T 28-03-2018 CWR44_RS09385 c7de4a15cb30d0003ea6b93c64e6ab18 341 Gene3D G3DSA:3.40.33.10 210 341 3.7E-16 T 28-03-2018 IPR014044 CAP domain CWR44_RS09385 c7de4a15cb30d0003ea6b93c64e6ab18 341 Pfam PF14504 CAP-associated N-terminal 70 204 2.0E-33 T 28-03-2018 IPR029410 CAP-associated domain CWR44_RS09140 2265052a726698af71fbec9a39c6b051 92 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 3 76 8.6E-11 T 28-03-2018 IPR006450 Phage protein of unkonwn function CWR44_RS09140 2265052a726698af71fbec9a39c6b051 92 Pfam PF05135 Phage gp6-like head-tail connector protein 1 90 1.1E-13 T 28-03-2018 IPR021146 Phage gp6-like head-tail connector protein CWR44_RS08365 46773be955943647ac893751281138dd 230 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 34 7.2E-8 T 28-03-2018 IPR019933 DivIVA domain CWR44_RS08365 46773be955943647ac893751281138dd 230 Pfam PF05103 DivIVA protein 4 133 2.9E-33 T 28-03-2018 IPR007793 DivIVA family CWR44_RS11250 0c1be723ae7cbb72979d97fa729a5c27 307 Gene3D G3DSA:1.25.40.10 9 260 1.3E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 PRINTS PR00481 Cytosol aminopeptidase signature 313 334 1.1E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 PRINTS PR00481 Cytosol aminopeptidase signature 254 271 1.1E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 PRINTS PR00481 Cytosol aminopeptidase signature 363 378 1.1E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 PRINTS PR00481 Cytosol aminopeptidase signature 335 355 1.1E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 PRINTS PR00481 Cytosol aminopeptidase signature 276 297 1.1E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 177 484 2.2E-103 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 339 346 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 SUPERFAMILY SSF52949 10 176 6.47E-24 T 28-03-2018 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 Gene3D G3DSA:3.40.630.10 165 489 5.4E-114 T 28-03-2018 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 34 145 1.2E-14 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 Gene3D G3DSA:3.40.220.10 7 154 2.0E-10 T 28-03-2018 CWR44_RS07275 830996d7fa66eda25abf9a1e5e33e478 489 SUPERFAMILY SSF53187 174 488 1.0E-105 T 28-03-2018 CWR44_RS07625 5fab569465397a43a389430edbbd07fd 452 Pfam PF02386 Cation transport protein 44 434 1.8E-60 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CWR44_RS10380 544619559d42f5f4dedf3b59480f4fb7 180 PIRSF PIRSF037778 1 180 9.6E-48 T 28-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CWR44_RS10380 544619559d42f5f4dedf3b59480f4fb7 180 Pfam PF12822 ECF transporter, substrate-specific component 5 172 1.8E-26 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 ProSitePatterns PS00786 5'-nucleotidase signature 2. 306 317 - T 28-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 SUPERFAMILY SSF56300 235 519 4.22E-69 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 Gene3D G3DSA:3.90.780.10 526 735 6.6E-51 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 Gene3D G3DSA:3.60.21.10 231 524 3.9E-64 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 PRINTS PR01607 Apyrase family signature 237 255 5.1E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 PRINTS PR01607 Apyrase family signature 461 481 5.1E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 PRINTS PR01607 Apyrase family signature 400 417 5.1E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 PRINTS PR01607 Apyrase family signature 675 694 5.1E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 PRINTS PR01607 Apyrase family signature 586 609 5.1E-21 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 Pfam PF02872 5'-nucleotidase, C-terminal domain 531 700 5.0E-42 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS05695 4a2bca5e610d897651331357b3ec2aa6 967 SUPERFAMILY SSF55816 526 735 1.06E-49 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CWR44_RS12495 f62a4068a7c1bf0bfae0b1df1da0c8f9 346 SUPERFAMILY SSF56235 104 323 2.78E-10 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS12495 f62a4068a7c1bf0bfae0b1df1da0c8f9 346 Gene3D G3DSA:3.60.60.10 97 335 6.0E-30 T 28-03-2018 CWR44_RS12495 f62a4068a7c1bf0bfae0b1df1da0c8f9 346 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 105 312 3.0E-69 T 28-03-2018 IPR005079 Peptidase C45 CWR44_RS09980 3e8f4e2c7f866c1f2ef9a4537eb00c47 239 SUPERFAMILY SSF51161 89 224 4.99E-50 T 28-03-2018 IPR011004 Trimeric LpxA-like CWR44_RS09980 3e8f4e2c7f866c1f2ef9a4537eb00c47 239 Gene3D G3DSA:3.30.70.250 4 83 3.6E-34 T 28-03-2018 CWR44_RS09980 3e8f4e2c7f866c1f2ef9a4537eb00c47 239 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 122 157 1.0E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS09980 3e8f4e2c7f866c1f2ef9a4537eb00c47 239 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 7 237 9.2E-117 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CWR44_RS09980 3e8f4e2c7f866c1f2ef9a4537eb00c47 239 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 2 236 43.883 T 28-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CWR44_RS09980 3e8f4e2c7f866c1f2ef9a4537eb00c47 239 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 6 88 4.2E-32 T 28-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CWR44_RS09980 3e8f4e2c7f866c1f2ef9a4537eb00c47 239 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 175 203 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWR44_RS09980 3e8f4e2c7f866c1f2ef9a4537eb00c47 239 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 166 201 1.6E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS09980 3e8f4e2c7f866c1f2ef9a4537eb00c47 239 Gene3D G3DSA:2.160.10.10 84 236 5.4E-43 T 28-03-2018 CWR44_RS02755 5d35bb2b88a96f4555b4dd21b7eae117 232 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 28 229 1.0E-83 T 28-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CWR44_RS02755 5d35bb2b88a96f4555b4dd21b7eae117 232 Gene3D G3DSA:3.40.50.300 44 226 1.4E-32 T 28-03-2018 CWR44_RS02755 5d35bb2b88a96f4555b4dd21b7eae117 232 Pfam PF13614 AAA domain 46 168 5.0E-11 T 28-03-2018 IPR025669 AAA domain CWR44_RS02755 5d35bb2b88a96f4555b4dd21b7eae117 232 SUPERFAMILY SSF52540 45 223 2.66E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03420 c1d3dcbb924c8b59563b3f8105b04e65 201 Pfam PF01944 Stage II sporulation protein M 22 193 9.6E-16 T 28-03-2018 IPR002798 Stage II sporulation protein M-like CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 335 343 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 PRINTS PR00067 Catalase signature 106 123 1.5E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 PRINTS PR00067 Catalase signature 290 317 1.5E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 PRINTS PR00067 Catalase signature 22 45 1.5E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 PRINTS PR00067 Catalase signature 85 103 1.5E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 PRINTS PR00067 Catalase signature 125 143 1.5E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 PRINTS PR00067 Catalase signature 322 348 1.5E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 SMART SM01060 9 398 1.4E-266 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 Pfam PF06628 Catalase-related immune-responsive 422 483 9.3E-23 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 ProSitePatterns PS00438 Catalase proximal active site signature. 45 61 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 SUPERFAMILY SSF56634 3 496 5.76E-201 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 Pfam PF00199 Catalase 12 393 2.9E-181 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 PIRSF PIRSF038928 1 488 7.5E-210 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS09365 1f89772aafd21a61e3de0eea5ea71340 503 Gene3D G3DSA:2.40.180.10 1 359 9.5E-156 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CWR44_RS11255 901c09b23c4d8be8c20d62bcf6bc623b 202 SUPERFAMILY SSF55811 65 188 2.98E-14 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CWR44_RS11255 901c09b23c4d8be8c20d62bcf6bc623b 202 Gene3D G3DSA:3.90.79.10 60 202 5.8E-10 T 28-03-2018 CWR44_RS11255 901c09b23c4d8be8c20d62bcf6bc623b 202 Pfam PF00293 NUDIX domain 65 199 8.6E-9 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CWR44_RS00555 83adbb1b44991dca7464a8929f67e0c8 79 Pfam PF10031 Small integral membrane protein (DUF2273) 19 66 8.1E-15 T 28-03-2018 IPR018730 Protein of unknown function DUF2273 CWR44_RS01520 3ba494a4f12b7a6a44b0189510d01c83 104 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 6 103 1.4E-23 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CWR44_RS01520 3ba494a4f12b7a6a44b0189510d01c83 104 Gene3D G3DSA:2.102.10.10 7 104 2.1E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CWR44_RS01520 3ba494a4f12b7a6a44b0189510d01c83 104 SUPERFAMILY SSF50022 4 104 1.44E-31 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CWR44_RS01520 3ba494a4f12b7a6a44b0189510d01c83 104 Pfam PF13806 Rieske-like [2Fe-2S] domain 7 102 1.4E-18 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CWR44_RS02890 55eb11b5b12260e4705bc7a2bf3189e2 512 Pfam PF00367 phosphotransferase system, EIIB 439 468 7.1E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS02890 55eb11b5b12260e4705bc7a2bf3189e2 512 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 413 494 2.6E-16 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS02890 55eb11b5b12260e4705bc7a2bf3189e2 512 SUPERFAMILY SSF55604 435 508 4.58E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS02890 55eb11b5b12260e4705bc7a2bf3189e2 512 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 448 465 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS02890 55eb11b5b12260e4705bc7a2bf3189e2 512 Gene3D G3DSA:3.30.1360.60 433 508 6.9E-24 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS02890 55eb11b5b12260e4705bc7a2bf3189e2 512 Pfam PF02378 Phosphotransferase system, EIIC 12 351 5.3E-94 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS08795 bf90eab8547f1e844b194e0b2778640a 238 Gene3D G3DSA:1.10.10.10 2 66 6.5E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS08795 bf90eab8547f1e844b194e0b2778640a 238 Gene3D G3DSA:3.40.1410.10 77 234 9.6E-24 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR44_RS08795 bf90eab8547f1e844b194e0b2778640a 238 SUPERFAMILY SSF46785 6 73 7.71E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS08795 bf90eab8547f1e844b194e0b2778640a 238 SUPERFAMILY SSF64288 79 232 1.4E-29 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CWR44_RS08795 bf90eab8547f1e844b194e0b2778640a 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 60 4.4E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CWR44_RS08795 bf90eab8547f1e844b194e0b2778640a 238 SMART SM00866 91 230 8.0E-15 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR44_RS08795 bf90eab8547f1e844b194e0b2778640a 238 Pfam PF07702 UTRA domain 92 226 8.7E-26 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CWR44_RS07330 8c60b7bf95724b80d734818a00d6ff66 126 SUPERFAMILY SSF141251 2 119 9.94E-50 T 28-03-2018 CWR44_RS07330 8c60b7bf95724b80d734818a00d6ff66 126 SMART SM01298 7 119 6.6E-74 T 28-03-2018 IPR014916 Kinase associated protein B CWR44_RS07330 8c60b7bf95724b80d734818a00d6ff66 126 Pfam PF08810 Kinase associated protein B 7 117 2.6E-43 T 28-03-2018 IPR014916 Kinase associated protein B CWR44_RS00960 2c470300fb33a7cf69b795ba824d2dc8 305 Gene3D G3DSA:3.40.50.1980 143 305 1.1E-25 T 28-03-2018 CWR44_RS00960 2c470300fb33a7cf69b795ba824d2dc8 305 SUPERFAMILY SSF53807 40 296 5.49E-49 T 28-03-2018 CWR44_RS00960 2c470300fb33a7cf69b795ba824d2dc8 305 Gene3D G3DSA:3.40.50.1980 31 142 4.5E-20 T 28-03-2018 CWR44_RS00960 2c470300fb33a7cf69b795ba824d2dc8 305 Pfam PF01497 Periplasmic binding protein 53 279 8.6E-30 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CWR44_RS11365 8e35bf1f7bb625bdd675ac73d596c9ba 288 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 13 284 8.2E-126 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11365 8e35bf1f7bb625bdd675ac73d596c9ba 288 Pfam PF01039 Carboxyl transferase domain 64 244 5.2E-18 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CWR44_RS11365 8e35bf1f7bb625bdd675ac73d596c9ba 288 Gene3D G3DSA:3.90.226.10 17 288 6.8E-70 T 28-03-2018 CWR44_RS11365 8e35bf1f7bb625bdd675ac73d596c9ba 288 SUPERFAMILY SSF52096 30 281 4.97E-81 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CWR44_RS11365 8e35bf1f7bb625bdd675ac73d596c9ba 288 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 283 38.809 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11365 8e35bf1f7bb625bdd675ac73d596c9ba 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 1.9E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11365 8e35bf1f7bb625bdd675ac73d596c9ba 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 1.9E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11365 8e35bf1f7bb625bdd675ac73d596c9ba 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 1.9E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11365 8e35bf1f7bb625bdd675ac73d596c9ba 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 1.9E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS11365 8e35bf1f7bb625bdd675ac73d596c9ba 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 1.9E-37 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CWR44_RS00170 6190c1f2cc3dcf132b7cc854d77a2b25 70 Pfam PF00137 ATP synthase subunit C 4 66 1.1E-14 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWR44_RS00170 6190c1f2cc3dcf132b7cc854d77a2b25 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00170 6190c1f2cc3dcf132b7cc854d77a2b25 70 SUPERFAMILY SSF81333 3 69 3.4E-20 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWR44_RS00170 6190c1f2cc3dcf132b7cc854d77a2b25 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 14 69 1.4E-22 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CWR44_RS00170 6190c1f2cc3dcf132b7cc854d77a2b25 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 15.978 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00170 6190c1f2cc3dcf132b7cc854d77a2b25 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 4.7E-20 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00170 6190c1f2cc3dcf132b7cc854d77a2b25 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 4.7E-20 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00170 6190c1f2cc3dcf132b7cc854d77a2b25 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 4.7E-20 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS00170 6190c1f2cc3dcf132b7cc854d77a2b25 70 Gene3D G3DSA:1.20.20.10 1 70 2.8E-21 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CWR44_RS05310 7c0c60e55d8bb89d5737a52a6a72a4a5 274 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 6.8E-31 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CWR44_RS05310 7c0c60e55d8bb89d5737a52a6a72a4a5 274 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 10 73 4.0E-31 T 28-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CWR44_RS05310 7c0c60e55d8bb89d5737a52a6a72a4a5 274 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 268 2.5E-109 T 28-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CWR44_RS05310 7c0c60e55d8bb89d5737a52a6a72a4a5 274 SUPERFAMILY SSF53271 95 260 1.24E-34 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWR44_RS05310 7c0c60e55d8bb89d5737a52a6a72a4a5 274 SUPERFAMILY SSF46785 2 74 2.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS05310 7c0c60e55d8bb89d5737a52a6a72a4a5 274 Pfam PF00156 Phosphoribosyl transferase domain 108 264 1.2E-20 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR44_RS05310 7c0c60e55d8bb89d5737a52a6a72a4a5 274 Gene3D G3DSA:3.40.50.2020 74 274 1.1E-30 T 28-03-2018 CWR44_RS05310 7c0c60e55d8bb89d5737a52a6a72a4a5 274 Gene3D G3DSA:1.10.10.10 1 73 7.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02245 7b962393d4b12d2760be20062ba5cece 192 SMART SM01266 4 59 1.2E-18 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CWR44_RS02245 7b962393d4b12d2760be20062ba5cece 192 Gene3D G3DSA:2.160.10.10 1 192 4.4E-54 T 28-03-2018 CWR44_RS02245 7b962393d4b12d2760be20062ba5cece 192 SUPERFAMILY SSF51161 2 188 1.94E-49 T 28-03-2018 IPR011004 Trimeric LpxA-like CWR44_RS02245 7b962393d4b12d2760be20062ba5cece 192 Pfam PF12464 Maltose acetyltransferase 6 55 3.6E-18 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CWR44_RS02245 7b962393d4b12d2760be20062ba5cece 192 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 74 104 0.0041 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS02245 7b962393d4b12d2760be20062ba5cece 192 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 130 165 2.0E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS02285 73e848863a9cc4db08edabc41813aa9f 285 SUPERFAMILY SSF48576 7 276 2.12E-64 T 28-03-2018 IPR008949 Isoprenoid synthase domain CWR44_RS02285 73e848863a9cc4db08edabc41813aa9f 285 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 127 142 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CWR44_RS02285 73e848863a9cc4db08edabc41813aa9f 285 Pfam PF00494 Squalene/phytoene synthase 16 271 1.3E-54 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CWR44_RS02285 73e848863a9cc4db08edabc41813aa9f 285 Gene3D G3DSA:1.10.600.10 1 284 1.4E-67 T 28-03-2018 IPR008949 Isoprenoid synthase domain CWR44_RS12825 59e5367e80f5223790d8edb57419dbd8 121 SUPERFAMILY SSF50118 1 112 3.6E-40 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CWR44_RS12825 59e5367e80f5223790d8edb57419dbd8 121 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 109 1.8E-33 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CWR44_RS12825 59e5367e80f5223790d8edb57419dbd8 121 Gene3D G3DSA:2.30.30.110 1 115 3.4E-39 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CWR44_RS12825 59e5367e80f5223790d8edb57419dbd8 121 PIRSF PIRSF033490 1 112 3.3E-39 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CWR44_RS07715 89ab604fb1ca8db86126dc8325649257 267 Gene3D G3DSA:3.40.50.1820 1 267 2.2E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS07715 89ab604fb1ca8db86126dc8325649257 267 Pfam PF12697 Alpha/beta hydrolase family 17 251 1.6E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS07715 89ab604fb1ca8db86126dc8325649257 267 SUPERFAMILY SSF53474 2 262 7.49E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS07715 89ab604fb1ca8db86126dc8325649257 267 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 14 261 8.6E-82 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 CWR44_RS07715 89ab604fb1ca8db86126dc8325649257 267 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 4 262 33.224 T 28-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 CWR44_RS03685 74e9548d54a18aa5406c1f59565061d3 312 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 306 3.0E-52 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CWR44_RS03685 74e9548d54a18aa5406c1f59565061d3 312 Gene3D G3DSA:1.10.3470.10 33 312 1.6E-39 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS02700 a32fd999699ee07659d3293ec4ac16dd 185 Pfam PF02397 Bacterial sugar transferase 2 178 2.1E-60 T 28-03-2018 IPR003362 Bacterial sugar transferase CWR44_RS07840 43aa379c11ce7560e9a5ed736af69ddc 86 Gene3D G3DSA:3.30.1280.10 1 80 5.4E-22 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS07840 43aa379c11ce7560e9a5ed736af69ddc 86 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 79 1.0E-34 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS07840 43aa379c11ce7560e9a5ed736af69ddc 86 SUPERFAMILY SSF82697 2 81 1.29E-21 T 28-03-2018 CWR44_RS07840 43aa379c11ce7560e9a5ed736af69ddc 86 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 79 1.6E-24 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS07840 43aa379c11ce7560e9a5ed736af69ddc 86 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 79 18.108 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS07840 43aa379c11ce7560e9a5ed736af69ddc 86 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 79 8.8E-22 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CWR44_RS03455 9500713f5f761e39e7e057aacf7d3a4d 112 Gene3D G3DSA:1.10.10.10 1 99 5.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03455 9500713f5f761e39e7e057aacf7d3a4d 112 Pfam PF03551 Transcriptional regulator PadR-like family 16 88 1.4E-21 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWR44_RS03455 9500713f5f761e39e7e057aacf7d3a4d 112 SUPERFAMILY SSF46785 5 108 2.15E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01335 4748f58ee8d3f40804b2a6adb5a1858e 533 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 10 529 6.3E-155 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CWR44_RS01335 4748f58ee8d3f40804b2a6adb5a1858e 533 Pfam PF02652 L-lactate permease 14 528 2.2E-157 T 28-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CWR44_RS06160 90a5c9221aee8a56476529bc3da3f35d 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 2.6E-11 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS06160 90a5c9221aee8a56476529bc3da3f35d 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 374 400 2.6E-11 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS06160 90a5c9221aee8a56476529bc3da3f35d 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 133 152 2.6E-11 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS06160 90a5c9221aee8a56476529bc3da3f35d 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 322 341 2.6E-11 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS06160 90a5c9221aee8a56476529bc3da3f35d 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 163 187 2.6E-11 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS06160 90a5c9221aee8a56476529bc3da3f35d 499 Pfam PF00361 Proton-conducting membrane transporter 128 417 9.0E-54 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS05175 b0e9035c78a252cb9ae9f4143b062f4f 482 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS05175 b0e9035c78a252cb9ae9f4143b062f4f 482 Pfam PF00367 phosphotransferase system, EIIB 9 42 3.8E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS05175 b0e9035c78a252cb9ae9f4143b062f4f 482 Pfam PF02378 Phosphotransferase system, EIIC 111 406 2.4E-40 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS05175 b0e9035c78a252cb9ae9f4143b062f4f 482 Gene3D G3DSA:3.30.1360.60 5 82 2.1E-25 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS05175 b0e9035c78a252cb9ae9f4143b062f4f 482 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 462 2.8E-197 T 28-03-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.201|MetaCyc: PWY-6619 CWR44_RS05175 b0e9035c78a252cb9ae9f4143b062f4f 482 SUPERFAMILY SSF55604 8 82 1.44E-20 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS05175 b0e9035c78a252cb9ae9f4143b062f4f 482 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 110 4.9E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS13080 684a1f28c0ceac992bf5d04487c7fbeb 40 SUPERFAMILY SSF56784 2 30 4.71E-6 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS13080 684a1f28c0ceac992bf5d04487c7fbeb 40 Pfam PF08282 haloacid dehalogenase-like hydrolase 2 31 7.8E-6 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS13080 684a1f28c0ceac992bf5d04487c7fbeb 40 Gene3D G3DSA:3.40.50.1000 1 32 5.3E-4 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS13210 684a1f28c0ceac992bf5d04487c7fbeb 40 SUPERFAMILY SSF56784 2 30 4.71E-6 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS13210 684a1f28c0ceac992bf5d04487c7fbeb 40 Pfam PF08282 haloacid dehalogenase-like hydrolase 2 31 7.8E-6 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS13210 684a1f28c0ceac992bf5d04487c7fbeb 40 Gene3D G3DSA:3.40.50.1000 1 32 5.3E-4 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS12305 8c4c9240ccc256276ebf36ada30924e8 348 Pfam PF07730 Histidine kinase 147 210 5.8E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CWR44_RS12305 8c4c9240ccc256276ebf36ada30924e8 348 Gene3D G3DSA:3.30.565.10 210 347 4.2E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS12305 8c4c9240ccc256276ebf36ada30924e8 348 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 249 340 9.2E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS12305 8c4c9240ccc256276ebf36ada30924e8 348 PIRSF PIRSF037431 2 347 3.6E-120 T 28-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 CWR44_RS12305 8c4c9240ccc256276ebf36ada30924e8 348 SUPERFAMILY SSF55874 221 338 6.42E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS12305 8c4c9240ccc256276ebf36ada30924e8 348 SMART SM00387 248 341 7.2E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CWR44_RS04025 772dbf5643be9388b7bb96344cc72ead 224 Pfam PF13610 DDE domain 72 203 1.5E-38 T 28-03-2018 IPR032874 DDE domain CWR44_RS04025 772dbf5643be9388b7bb96344cc72ead 224 Gene3D G3DSA:1.10.10.10 5 68 4.8E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04025 772dbf5643be9388b7bb96344cc72ead 224 SUPERFAMILY SSF53098 69 216 6.83E-11 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS04025 772dbf5643be9388b7bb96344cc72ead 224 Gene3D G3DSA:3.30.420.10 69 218 3.2E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS00685 39c96d3fe2b878dd71928df6ea73e966 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.0E-39 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CWR44_RS00685 39c96d3fe2b878dd71928df6ea73e966 72 SUPERFAMILY SSF50249 1 71 4.93E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS00685 39c96d3fe2b878dd71928df6ea73e966 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 2.0E-28 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CWR44_RS00685 39c96d3fe2b878dd71928df6ea73e966 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.221 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CWR44_RS00685 39c96d3fe2b878dd71928df6ea73e966 72 SMART SM00316 4 72 8.5E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS00685 39c96d3fe2b878dd71928df6ea73e966 72 Gene3D G3DSA:2.40.50.140 1 72 1.6E-37 T 28-03-2018 CWR44_RS05760 b2407259cf23b621edfd616acbb1c3c7 157 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 8 149 45.877 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CWR44_RS05760 b2407259cf23b621edfd616acbb1c3c7 157 Gene3D G3DSA:3.40.140.10 1 156 3.3E-50 T 28-03-2018 CWR44_RS05760 b2407259cf23b621edfd616acbb1c3c7 157 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CWR44_RS05760 b2407259cf23b621edfd616acbb1c3c7 157 SUPERFAMILY SSF53927 2 150 2.01E-53 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CWR44_RS05760 b2407259cf23b621edfd616acbb1c3c7 157 Pfam PF14437 MafB19-like deaminase 3 149 7.1E-43 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CWR44_RS09820 57035f572e6dd1eddd7e356887332df2 840 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 529 820 3.4E-78 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CWR44_RS09820 57035f572e6dd1eddd7e356887332df2 840 Gene3D G3DSA:3.40.630.30 629 813 3.3E-12 T 28-03-2018 CWR44_RS09820 57035f572e6dd1eddd7e356887332df2 840 SUPERFAMILY SSF55729 639 820 4.5E-10 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS09820 57035f572e6dd1eddd7e356887332df2 840 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 18 289 5.4E-15 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CWR44_RS01395 3d2936801595c7aa27ae17f1af87ddc7 202 Pfam PF07987 Domain of unkown function (DUF1775) 25 151 1.8E-20 T 28-03-2018 IPR012533 YcnI-like CWR44_RS01255 b9ccb8b65adcfc15b0aade6e1615cfc4 215 Pfam PF13533 Biotin-lipoyl like 43 74 3.0E-8 T 28-03-2018 CWR44_RS01255 b9ccb8b65adcfc15b0aade6e1615cfc4 215 Pfam PF13437 HlyD family secretion protein 91 198 1.0E-10 T 28-03-2018 CWR44_RS01255 b9ccb8b65adcfc15b0aade6e1615cfc4 215 SUPERFAMILY SSF51230 49 116 4.85E-8 T 28-03-2018 IPR011053 Single hybrid motif CWR44_RS01255 b9ccb8b65adcfc15b0aade6e1615cfc4 215 Gene3D G3DSA:2.40.50.100 42 116 4.0E-15 T 28-03-2018 CWR44_RS02495 b03e13394a79fe54c489100e00093ede 276 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 11 274 55.035 T 28-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CWR44_RS02495 b03e13394a79fe54c489100e00093ede 276 Pfam PF03618 Kinase/pyrophosphorylase 13 268 7.2E-87 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CWR44_RS02495 b03e13394a79fe54c489100e00093ede 276 Gene3D G3DSA:3.40.50.300 71 276 0.0017 T 28-03-2018 CWR44_RS11610 f763973650496dc4545c2ef699a9d45f 214 Pfam PF02390 Putative methyltransferase 38 206 1.1E-49 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CWR44_RS11610 f763973650496dc4545c2ef699a9d45f 214 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 211 29.171 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CWR44_RS11610 f763973650496dc4545c2ef699a9d45f 214 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 29 208 1.1E-55 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CWR44_RS11610 f763973650496dc4545c2ef699a9d45f 214 SUPERFAMILY SSF53335 29 207 5.57E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS11610 f763973650496dc4545c2ef699a9d45f 214 Gene3D G3DSA:3.40.50.150 1 210 4.2E-25 T 28-03-2018 CWR44_RS00670 e6bdf521b54659049c8e35e5ba4fbaf3 129 SUPERFAMILY SSF53137 14 129 2.42E-49 T 28-03-2018 CWR44_RS00670 e6bdf521b54659049c8e35e5ba4fbaf3 129 Gene3D G3DSA:3.30.420.80 5 129 4.0E-44 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00670 e6bdf521b54659049c8e35e5ba4fbaf3 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site CWR44_RS00670 e6bdf521b54659049c8e35e5ba4fbaf3 129 Pfam PF00411 Ribosomal protein S11 19 128 8.3E-51 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00670 e6bdf521b54659049c8e35e5ba4fbaf3 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.288 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00670 e6bdf521b54659049c8e35e5ba4fbaf3 129 PIRSF PIRSF002131 1 129 8.6E-54 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CWR44_RS00670 e6bdf521b54659049c8e35e5ba4fbaf3 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 2.5E-59 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS03835 bfc38ce61a9127ea906ad2cc29041b35 254 SUPERFAMILY SSF161098 57 244 1.44E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03835 bfc38ce61a9127ea906ad2cc29041b35 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 222 1.5E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03835 bfc38ce61a9127ea906ad2cc29041b35 254 Gene3D G3DSA:1.10.3720.10 2 251 3.2E-34 T 28-03-2018 CWR44_RS08635 c6112787553caf4bbd7372ab5fc47bf0 255 SUPERFAMILY SSF53098 68 254 4.55E-64 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS08635 c6112787553caf4bbd7372ab5fc47bf0 255 Hamap MF_00052_B Ribonuclease HII [rnhB]. 73 251 34.788 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 CWR44_RS08635 c6112787553caf4bbd7372ab5fc47bf0 255 Gene3D G3DSA:3.30.420.10 49 255 6.1E-65 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS08635 c6112787553caf4bbd7372ab5fc47bf0 255 Pfam PF01351 Ribonuclease HII 75 249 7.2E-36 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CWR44_RS10740 c3208f62830382942f5a6ef400330512 271 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 268 56.792 T 28-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CWR44_RS10740 c3208f62830382942f5a6ef400330512 271 Pfam PF03618 Kinase/pyrophosphorylase 6 263 5.7E-93 T 28-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CWR44_RS10740 c3208f62830382942f5a6ef400330512 271 Gene3D G3DSA:3.40.50.300 15 271 5.6E-5 T 28-03-2018 CWR44_RS05930 5d624f4cd123ce28392a2b824b2ad644 280 Gene3D G3DSA:3.30.930.10 4 268 1.8E-35 T 28-03-2018 CWR44_RS05930 5d624f4cd123ce28392a2b824b2ad644 280 Pfam PF03099 Biotin/lipoate A/B protein ligase family 80 180 7.5E-13 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CWR44_RS05930 5d624f4cd123ce28392a2b824b2ad644 280 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 6 275 47.579 T 28-03-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|MetaCyc: PWY-6987 CWR44_RS05930 5d624f4cd123ce28392a2b824b2ad644 280 SUPERFAMILY SSF55681 7 268 1.74E-65 T 28-03-2018 CWR44_RS11235 cdb2036d808d879f2ed5d384fe1a9db8 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 43 92 6.1E-12 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS11235 cdb2036d808d879f2ed5d384fe1a9db8 438 Pfam PF01610 Transposase 164 417 9.4E-56 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS08975 529e21419fd494473be0b5e472e93694 113 SUPERFAMILY SSF47413 6 70 1.18E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS08975 529e21419fd494473be0b5e472e93694 113 Gene3D G3DSA:1.10.260.40 1 113 5.3E-22 T 28-03-2018 CWR44_RS08975 529e21419fd494473be0b5e472e93694 113 SMART SM00530 13 68 5.4E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS08975 529e21419fd494473be0b5e472e93694 113 Pfam PF01381 Helix-turn-helix 14 68 3.1E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS11100 1e2e3ddff8ad12fa161f2a34806b9701 341 SUPERFAMILY SSF111337 1 341 6.93E-140 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWR44_RS11100 1e2e3ddff8ad12fa161f2a34806b9701 341 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 341 2.1E-145 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWR44_RS11100 1e2e3ddff8ad12fa161f2a34806b9701 341 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 341 46.703 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWR44_RS11100 1e2e3ddff8ad12fa161f2a34806b9701 341 Gene3D G3DSA:3.40.1780.10 1 133 5.1E-43 T 28-03-2018 CWR44_RS11100 1e2e3ddff8ad12fa161f2a34806b9701 341 Gene3D G3DSA:3.40.1780.10 173 341 7.5E-67 T 28-03-2018 CWR44_RS11100 1e2e3ddff8ad12fa161f2a34806b9701 341 Pfam PF02547 Queuosine biosynthesis protein 4 340 7.6E-142 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CWR44_RS01035 756d3577ec5d9c9f9ccc51314b5d4854 374 SUPERFAMILY SSF51905 256 355 1.05E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01035 756d3577ec5d9c9f9ccc51314b5d4854 374 SUPERFAMILY SSF51905 1 161 1.05E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS01035 756d3577ec5d9c9f9ccc51314b5d4854 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.5E-17 T 28-03-2018 CWR44_RS01035 756d3577ec5d9c9f9ccc51314b5d4854 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 300 2.5E-17 T 28-03-2018 CWR44_RS01035 756d3577ec5d9c9f9ccc51314b5d4854 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 2.5E-17 T 28-03-2018 CWR44_RS01035 756d3577ec5d9c9f9ccc51314b5d4854 374 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 140 155 2.5E-17 T 28-03-2018 CWR44_RS01035 756d3577ec5d9c9f9ccc51314b5d4854 374 Pfam PF01494 FAD binding domain 2 330 6.7E-20 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CWR44_RS01035 756d3577ec5d9c9f9ccc51314b5d4854 374 Gene3D G3DSA:3.50.50.60 1 336 2.7E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS00465 439316f4d9e8eb49e6f76180d79643c6 355 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 112 348 1.8E-87 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CWR44_RS00465 439316f4d9e8eb49e6f76180d79643c6 355 Hamap MF_02040 Iron-sulfur cluster carrier protein. 101 349 33.795 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CWR44_RS00465 439316f4d9e8eb49e6f76180d79643c6 355 Gene3D G3DSA:3.40.50.300 95 322 1.3E-52 T 28-03-2018 CWR44_RS00465 439316f4d9e8eb49e6f76180d79643c6 355 SUPERFAMILY SSF52540 112 350 7.32E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS00465 439316f4d9e8eb49e6f76180d79643c6 355 Gene3D G3DSA:3.30.300.130 2 94 4.7E-6 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CWR44_RS00465 439316f4d9e8eb49e6f76180d79643c6 355 ProSitePatterns PS01215 Mrp family signature. 214 230 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 CWR44_RS11275 2f6e53ed6ce5d74e99808f3c0a27342e 497 ProSitePatterns PS00218 Amino acid permeases signature. 44 75 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CWR44_RS11275 2f6e53ed6ce5d74e99808f3c0a27342e 497 PIRSF PIRSF006060 2 497 2.4E-88 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS11275 2f6e53ed6ce5d74e99808f3c0a27342e 497 Pfam PF00324 Amino acid permease 19 477 3.8E-134 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 Pfam PF13932 GidA associated domain 399 612 1.7E-79 T 28-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 Gene3D G3DSA:3.50.50.60 2 262 2.6E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 365 388 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 SUPERFAMILY SSF51905 3 64 1.02E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 SUPERFAMILY SSF51905 95 258 1.02E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 Pfam PF01134 Glucose inhibited division protein A 6 394 6.4E-169 T 28-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 270 284 - T 28-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 5 617 3.5E-288 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 3 620 41.976 T 28-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 158 2.3E-5 T 28-03-2018 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.3E-5 T 28-03-2018 CWR44_RS04465 36751c3e283303e84b68d2b6c35f2d16 625 SMART SM01228 542 613 2.1E-41 T 28-03-2018 CWR44_RS03330 f586c3479fce9df5610029346b559966 62 Pfam PF01381 Helix-turn-helix 5 59 4.1E-18 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS03330 f586c3479fce9df5610029346b559966 62 SMART SM00530 4 59 2.4E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS03330 f586c3479fce9df5610029346b559966 62 SUPERFAMILY SSF47413 2 60 8.85E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS03330 f586c3479fce9df5610029346b559966 62 Gene3D G3DSA:1.10.260.40 1 62 1.6E-18 T 28-03-2018 CWR44_RS10035 ff211f183f00e70167f35265fa249159 629 Gene3D G3DSA:3.40.50.410 433 626 7.5E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A CWR44_RS10035 ff211f183f00e70167f35265fa249159 629 SUPERFAMILY SSF53300 437 623 1.32E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A CWR44_RS10035 ff211f183f00e70167f35265fa249159 629 Pfam PF00092 von Willebrand factor type A domain 439 594 9.8E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CWR44_RS10035 ff211f183f00e70167f35265fa249159 629 SMART SM00327 434 625 1.3E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A CWR44_RS06685 b802effcc16cfe31a522e0313fa9b914 132 Pfam PF07972 NrdI Flavodoxin like 3 114 6.2E-33 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CWR44_RS06685 b802effcc16cfe31a522e0313fa9b914 132 SUPERFAMILY SSF52218 2 121 1.37E-20 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS06685 b802effcc16cfe31a522e0313fa9b914 132 Gene3D G3DSA:3.40.50.360 1 123 1.7E-16 T 28-03-2018 IPR029039 Flavoprotein-like domain CWR44_RS06685 b802effcc16cfe31a522e0313fa9b914 132 PIRSF PIRSF005087 1 128 9.1E-40 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CWR44_RS06685 b802effcc16cfe31a522e0313fa9b914 132 Hamap MF_00128 Protein NrdI [nrdI]. 1 124 26.479 T 28-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial CWR44_RS06685 b802effcc16cfe31a522e0313fa9b914 132 TIGRFAM TIGR00333 nrdI: nrdI protein 3 121 6.2E-33 T 28-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CWR44_RS10755 96080632b3e9b33955cd23144f392056 250 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 245 4.5E-64 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CWR44_RS10755 96080632b3e9b33955cd23144f392056 250 SUPERFAMILY SSF57863 80 233 2.88E-22 T 28-03-2018 CWR44_RS10755 96080632b3e9b33955cd23144f392056 250 SUPERFAMILY SSF50249 1 78 1.66E-12 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS10755 96080632b3e9b33955cd23144f392056 250 Hamap MF_00201 DNA repair protein RecO [recO]. 1 245 19.682 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CWR44_RS10755 96080632b3e9b33955cd23144f392056 250 Pfam PF11967 Recombination protein O N terminal 1 78 1.4E-16 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CWR44_RS10755 96080632b3e9b33955cd23144f392056 250 Gene3D G3DSA:2.40.50.140 1 81 3.9E-18 T 28-03-2018 CWR44_RS10755 96080632b3e9b33955cd23144f392056 250 Pfam PF02565 Recombination protein O C terminal 82 237 1.5E-19 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CWR44_RS07760 94fef1280d1b44622ba05fe869b90ff5 156 ProDom PD034207 SA0907 SIMILAR ORF2 TRANSCRIPTIONAL AUTOLYSIN SAV1055 MW0938 ATLR CDS REGULATOR 1 156 3.0E-89 T 28-03-2018 IPR024469 Protein of unknown function DUF2538 CWR44_RS07760 94fef1280d1b44622ba05fe869b90ff5 156 Pfam PF10804 Protein of unknown function (DUF2538) 1 155 5.3E-90 T 28-03-2018 IPR024469 Protein of unknown function DUF2538 CWR44_RS06265 2582feeb94198fd65fae9b23e2507b9e 277 PIRSF PIRSF006483 1 277 5.1E-78 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR44_RS06265 2582feeb94198fd65fae9b23e2507b9e 277 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 210 2.8E-58 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CWR44_RS06265 2582feeb94198fd65fae9b23e2507b9e 277 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 2.4E-21 T 28-03-2018 IPR019264 Domain of unknown function DUF2179 CWR44_RS01910 4710de609a0e1fe66ec3ddb35d06b413 240 Gene3D G3DSA:1.10.1660.10 1 59 2.5E-20 T 28-03-2018 CWR44_RS01910 4710de609a0e1fe66ec3ddb35d06b413 240 Gene3D G3DSA:1.10.1660.10 60 138 4.1E-9 T 28-03-2018 CWR44_RS01910 4710de609a0e1fe66ec3ddb35d06b413 240 SMART SM00422 4 73 5.1E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS01910 4710de609a0e1fe66ec3ddb35d06b413 240 Pfam PF13411 MerR HTH family regulatory protein 4 71 4.7E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS01910 4710de609a0e1fe66ec3ddb35d06b413 240 SUPERFAMILY SSF46955 4 121 1.36E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain CWR44_RS01910 4710de609a0e1fe66ec3ddb35d06b413 240 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS01910 4710de609a0e1fe66ec3ddb35d06b413 240 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS01910 4710de609a0e1fe66ec3ddb35d06b413 240 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 2.9E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CWR44_RS07830 25664abb9ec4118d04fa7d32f41ed291 374 Gene3D G3DSA:3.40.50.20 10 94 1.0E-25 T 28-03-2018 CWR44_RS07830 25664abb9ec4118d04fa7d32f41ed291 374 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 11 364 1.5E-112 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CWR44_RS07830 25664abb9ec4118d04fa7d32f41ed291 374 Gene3D G3DSA:3.30.1490.20 123 185 3.4E-14 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CWR44_RS07830 25664abb9ec4118d04fa7d32f41ed291 374 SUPERFAMILY SSF51246 308 366 6.04E-17 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CWR44_RS07830 25664abb9ec4118d04fa7d32f41ed291 374 Gene3D G3DSA:3.30.470.20 186 371 2.1E-32 T 28-03-2018 CWR44_RS07830 25664abb9ec4118d04fa7d32f41ed291 374 SUPERFAMILY SSF52440 11 102 1.21E-26 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CWR44_RS07830 25664abb9ec4118d04fa7d32f41ed291 374 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 9 76 3.6E-7 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CWR44_RS07830 25664abb9ec4118d04fa7d32f41ed291 374 Pfam PF02222 ATP-grasp domain 116 283 1.4E-43 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CWR44_RS07830 25664abb9ec4118d04fa7d32f41ed291 374 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 11 359 38.989 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CWR44_RS07830 25664abb9ec4118d04fa7d32f41ed291 374 SUPERFAMILY SSF56059 107 302 2.65E-54 T 28-03-2018 CWR44_RS01290 63f849209e7f484ca64efd00d356c2e9 318 Pfam PF02698 DUF218 domain 148 268 7.0E-30 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CWR44_RS01290 63f849209e7f484ca64efd00d356c2e9 318 Gene3D G3DSA:3.40.50.620 140 280 1.2E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS03065 cb5f70e8d5f622af43260287b6fae45b 389 Gene3D G3DSA:1.20.1250.20 193 384 1.2E-12 T 28-03-2018 CWR44_RS03065 cb5f70e8d5f622af43260287b6fae45b 389 SUPERFAMILY SSF103473 4 378 5.62E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS03065 cb5f70e8d5f622af43260287b6fae45b 389 Gene3D G3DSA:1.20.1250.20 2 192 2.6E-20 T 28-03-2018 CWR44_RS03065 cb5f70e8d5f622af43260287b6fae45b 389 Pfam PF07690 Major Facilitator Superfamily 12 346 4.2E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS05100 bba6d9b361c36554ed9cb4685a117547 442 SUPERFAMILY SSF161070 6 441 2.35E-114 T 28-03-2018 CWR44_RS05100 bba6d9b361c36554ed9cb4685a117547 442 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 422 442 1.2E-15 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CWR44_RS05100 bba6d9b361c36554ed9cb4685a117547 442 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.2E-15 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CWR44_RS05100 bba6d9b361c36554ed9cb4685a117547 442 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 1.2E-15 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CWR44_RS05100 bba6d9b361c36554ed9cb4685a117547 442 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.2E-15 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CWR44_RS05100 bba6d9b361c36554ed9cb4685a117547 442 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CWR44_RS05100 bba6d9b361c36554ed9cb4685a117547 442 Pfam PF00209 Sodium:neurotransmitter symporter family 6 126 3.7E-20 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CWR44_RS05100 bba6d9b361c36554ed9cb4685a117547 442 Pfam PF00209 Sodium:neurotransmitter symporter family 152 441 3.8E-26 T 28-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CWR44_RS03435 ef3c8b373232a87dc8713aadbfb77e7c 301 Pfam PF00892 EamA-like transporter family 9 149 1.0E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR44_RS03435 ef3c8b373232a87dc8713aadbfb77e7c 301 Pfam PF00892 EamA-like transporter family 160 287 1.4E-7 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CWR44_RS03435 ef3c8b373232a87dc8713aadbfb77e7c 301 TIGRFAM TIGR00688 rarD: protein RarD 8 263 3.2E-65 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 CWR44_RS03435 ef3c8b373232a87dc8713aadbfb77e7c 301 SUPERFAMILY SSF103481 193 289 4.32E-11 T 28-03-2018 CWR44_RS03435 ef3c8b373232a87dc8713aadbfb77e7c 301 SUPERFAMILY SSF103481 42 150 8.5E-10 T 28-03-2018 CWR44_RS08815 cdf830b7eae4216c5d51d75dc76d4466 276 Pfam PF11868 Protein of unknown function (DUF3388) 75 261 6.3E-99 T 28-03-2018 IPR024514 Domain of unknown function DUF3388 CWR44_RS08815 cdf830b7eae4216c5d51d75dc76d4466 276 SUPERFAMILY SSF55021 9 73 1.88E-5 T 28-03-2018 CWR44_RS08815 cdf830b7eae4216c5d51d75dc76d4466 276 PIRSF PIRSF021288 4 276 3.6E-148 T 28-03-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain CWR44_RS08815 cdf830b7eae4216c5d51d75dc76d4466 276 Gene3D G3DSA:3.30.70.260 14 83 5.6E-4 T 28-03-2018 CWR44_RS11210 7e6996a7651b899513071b1060d3a5d1 226 Pfam PF02602 Uroporphyrinogen-III synthase HemD 19 214 1.7E-36 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11210 7e6996a7651b899513071b1060d3a5d1 226 Gene3D G3DSA:3.40.50.10090 129 225 2.1E-12 T 28-03-2018 CWR44_RS11210 7e6996a7651b899513071b1060d3a5d1 226 SUPERFAMILY SSF69618 19 222 1.05E-42 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CWR44_RS11210 7e6996a7651b899513071b1060d3a5d1 226 Gene3D G3DSA:3.40.50.10090 29 128 4.5E-16 T 28-03-2018 CWR44_RS08325 a3c4f9210e8854e9e2c32d522bf83482 442 Gene3D G3DSA:3.10.20.310 195 275 3.1E-4 T 28-03-2018 CWR44_RS08325 a3c4f9210e8854e9e2c32d522bf83482 442 Pfam PF08478 POTRA domain, FtsQ-type 198 265 1.8E-15 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type CWR44_RS08325 a3c4f9210e8854e9e2c32d522bf83482 442 Hamap MF_00912 Cell division protein DivIB [divIB]. 156 411 27.589 T 28-03-2018 IPR026580 Cell division protein DivIB CWR44_RS10010 697fcc78dbbebde84594c7574a984a0d 102 Pfam PF06279 Protein of unknown function (DUF1033) 1 93 1.4E-18 T 28-03-2018 IPR010434 Protein of unknown function DUF1033 CWR44_RS07280 cd855d6842b5e814088efedae47ab3b4 439 Pfam PF13726 Na+-H+ antiporter family 3 89 2.5E-31 T 28-03-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal CWR44_RS07280 cd855d6842b5e814088efedae47ab3b4 439 Pfam PF03553 Na+/H+ antiporter family 151 432 1.1E-63 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CWR44_RS11525 b39fccb4fcb7fc30cd3e47ec47b0582c 304 Pfam PF00912 Transglycosylase 81 269 7.8E-54 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWR44_RS11525 b39fccb4fcb7fc30cd3e47ec47b0582c 304 Gene3D G3DSA:1.10.3810.10 74 286 6.6E-60 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CWR44_RS11525 b39fccb4fcb7fc30cd3e47ec47b0582c 304 SUPERFAMILY SSF53955 76 297 3.66E-57 T 28-03-2018 IPR023346 Lysozyme-like domain CWR44_RS06385 ff3b8b6b7cd2cd6d7bc7dbb76dadc0af 367 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 11 338 2.0E-12 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CWR44_RS06385 ff3b8b6b7cd2cd6d7bc7dbb76dadc0af 367 Gene3D G3DSA:3.20.20.210 2 367 5.4E-90 T 28-03-2018 CWR44_RS06385 ff3b8b6b7cd2cd6d7bc7dbb76dadc0af 367 SUPERFAMILY SSF51726 8 364 1.14E-82 T 28-03-2018 CWR44_RS00060 0f409b6759c6090ceb4335944d6c87ae 68 Gene3D G3DSA:3.30.70.100 4 67 2.5E-6 T 28-03-2018 CWR44_RS00060 0f409b6759c6090ceb4335944d6c87ae 68 SUPERFAMILY SSF55008 6 66 2.49E-7 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS12890 0f409b6759c6090ceb4335944d6c87ae 68 Gene3D G3DSA:3.30.70.100 4 67 2.5E-6 T 28-03-2018 CWR44_RS12890 0f409b6759c6090ceb4335944d6c87ae 68 SUPERFAMILY SSF55008 6 66 2.49E-7 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CWR44_RS05595 f7b2c9a241f0229b87e280e5bbda874b 66 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 14 42 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS05595 f7b2c9a241f0229b87e280e5bbda874b 66 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 13 65 1.2E-21 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CWR44_RS05595 f7b2c9a241f0229b87e280e5bbda874b 66 Gene3D G3DSA:1.20.5.1030 13 62 6.7E-20 T 28-03-2018 CWR44_RS05595 f7b2c9a241f0229b87e280e5bbda874b 66 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 13 65 5.9E-19 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS05595 f7b2c9a241f0229b87e280e5bbda874b 66 Hamap MF_00422 Protein translocase subunit SecE [secE]. 9 64 12.851 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CWR44_RS06155 2261aa85a8dfe29440fb6a80f4df5eeb 116 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 108 1.3E-28 T 28-03-2018 CWR44_RS07485 0a4d9aed2c3ca0dc5a12de7df3310c24 314 SMART SM00382 38 240 2.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS07485 0a4d9aed2c3ca0dc5a12de7df3310c24 314 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CWR44_RS07485 0a4d9aed2c3ca0dc5a12de7df3310c24 314 Gene3D G3DSA:3.40.50.300 5 314 9.4E-80 T 28-03-2018 CWR44_RS07485 0a4d9aed2c3ca0dc5a12de7df3310c24 314 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 271 4.5E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CWR44_RS07485 0a4d9aed2c3ca0dc5a12de7df3310c24 314 Pfam PF00005 ABC transporter 30 182 5.8E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS07485 0a4d9aed2c3ca0dc5a12de7df3310c24 314 SUPERFAMILY SSF52540 8 254 1.86E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05680 c7c5e55b4cd3aeaff29be6c0c854f72e 168 SUPERFAMILY SSF55729 2 149 9.76E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS05680 c7c5e55b4cd3aeaff29be6c0c854f72e 168 Pfam PF13302 Acetyltransferase (GNAT) domain 2 145 2.2E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS05680 c7c5e55b4cd3aeaff29be6c0c854f72e 168 Gene3D G3DSA:3.40.630.30 1 158 1.4E-17 T 28-03-2018 CWR44_RS10345 8a1e66c72655524ec4467c71a6cb177a 218 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 213 4.7E-71 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CWR44_RS10345 8a1e66c72655524ec4467c71a6cb177a 218 Gene3D G3DSA:3.40.50.300 1 218 8.2E-48 T 28-03-2018 CWR44_RS10345 8a1e66c72655524ec4467c71a6cb177a 218 Pfam PF02224 Cytidylate kinase 6 216 6.4E-70 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CWR44_RS10345 8a1e66c72655524ec4467c71a6cb177a 218 Hamap MF_00238 Cytidylate kinase [cmk]. 4 218 31.522 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CWR44_RS10345 8a1e66c72655524ec4467c71a6cb177a 218 SUPERFAMILY SSF52540 1 217 9.42E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS12430 4dcde4280628fe33686fcbc91a3c00a1 56 Pfam PF14044 NETI protein 2 54 8.1E-26 T 28-03-2018 IPR025930 NETI protein CWR44_RS05895 1a5ede70fa11c18b7229781c14514f20 127 Pfam PF17261 Family of unknown function (DUF5327) 4 127 2.7E-10 T 28-03-2018 IPR035218 Protein of unknown function DUF5327 CWR44_RS02070 fb055daf320cbafe7af9c9bf7dcfe342 298 Gene3D G3DSA:1.10.4100.10 20 270 1.3E-26 T 28-03-2018 CWR44_RS02070 fb055daf320cbafe7af9c9bf7dcfe342 298 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 293 3.0E-112 T 28-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CWR44_RS02070 fb055daf320cbafe7af9c9bf7dcfe342 298 Pfam PF03313 Serine dehydratase alpha chain 15 276 2.7E-69 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CWR44_RS01240 dad5831cbbe60607a4a58736c512af04 299 Gene3D G3DSA:3.40.50.1820 8 299 7.2E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS01240 dad5831cbbe60607a4a58736c512af04 299 Pfam PF07859 alpha/beta hydrolase fold 78 279 6.7E-36 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CWR44_RS01240 dad5831cbbe60607a4a58736c512af04 299 SUPERFAMILY SSF53474 22 291 5.54E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS04970 d2d7bcd1f74973b92cf9691e8cdd9e10 289 SMART SM00942 225 289 1.6E-24 T 28-03-2018 IPR014820 Primase, C-terminal 1 CWR44_RS04970 d2d7bcd1f74973b92cf9691e8cdd9e10 289 Pfam PF08708 Primase C terminal 1 (PriCT-1) 225 287 8.3E-13 T 28-03-2018 IPR014820 Primase, C-terminal 1 CWR44_RS03400 ef413b8f4fc532428e24a60afac1a754 210 Gene3D G3DSA:3.40.1800.10 114 207 3.1E-8 T 28-03-2018 CWR44_RS03400 ef413b8f4fc532428e24a60afac1a754 210 Pfam PF01844 HNH endonuclease 140 194 4.7E-11 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CWR44_RS03400 ef413b8f4fc532428e24a60afac1a754 210 SMART SM00507 126 190 0.001 T 28-03-2018 IPR003615 HNH nuclease CWR44_RS01945 7e0d058a2b155ca8728a1ea4df660fe3 197 Gene3D G3DSA:3.20.20.70 4 192 4.5E-13 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS01945 7e0d058a2b155ca8728a1ea4df660fe3 197 SUPERFAMILY SSF51391 26 181 4.19E-30 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS01945 7e0d058a2b155ca8728a1ea4df660fe3 197 Pfam PF02581 Thiamine monophosphate synthase 57 176 9.1E-22 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CWR44_RS06645 eb13271e4f86ac2dffecfa6333e8cdd3 504 Pfam PF00854 POT family 99 471 2.6E-67 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CWR44_RS06645 eb13271e4f86ac2dffecfa6333e8cdd3 504 Gene3D G3DSA:1.20.1250.20 12 216 1.2E-22 T 28-03-2018 CWR44_RS06645 eb13271e4f86ac2dffecfa6333e8cdd3 504 Gene3D G3DSA:1.20.1250.20 287 499 2.3E-13 T 28-03-2018 CWR44_RS06645 eb13271e4f86ac2dffecfa6333e8cdd3 504 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 500 7.5E-124 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CWR44_RS06645 eb13271e4f86ac2dffecfa6333e8cdd3 504 SUPERFAMILY SSF103473 16 310 3.66E-25 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS06645 eb13271e4f86ac2dffecfa6333e8cdd3 504 SUPERFAMILY SSF103473 344 497 6.54E-11 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS06645 eb13271e4f86ac2dffecfa6333e8cdd3 504 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 160 172 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CWR44_RS04615 08797596cd9f6c61f9b1ef1a571322d7 268 Pfam PF01183 Glycosyl hydrolases family 25 80 247 1.8E-23 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CWR44_RS04615 08797596cd9f6c61f9b1ef1a571322d7 268 Gene3D G3DSA:3.20.20.80 71 264 7.4E-32 T 28-03-2018 CWR44_RS04615 08797596cd9f6c61f9b1ef1a571322d7 268 SUPERFAMILY SSF51445 77 262 1.68E-35 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CWR44_RS04305 57a6db582fd3012e0b20f4cda274d35b 224 Gene3D G3DSA:3.30.420.10 70 218 8.1E-17 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS04305 57a6db582fd3012e0b20f4cda274d35b 224 Gene3D G3DSA:1.10.10.10 5 69 3.5E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04305 57a6db582fd3012e0b20f4cda274d35b 224 SUPERFAMILY SSF53098 69 216 4.3E-10 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CWR44_RS04305 57a6db582fd3012e0b20f4cda274d35b 224 Pfam PF13610 DDE domain 72 203 1.1E-38 T 28-03-2018 IPR032874 DDE domain CWR44_RS02470 62d6596f76edc448abd4ca3ca2c11893 192 Pfam PF03551 Transcriptional regulator PadR-like family 54 123 1.3E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CWR44_RS02470 62d6596f76edc448abd4ca3ca2c11893 192 Gene3D G3DSA:1.10.10.10 40 134 5.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS02470 62d6596f76edc448abd4ca3ca2c11893 192 SUPERFAMILY SSF46785 37 127 2.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS00645 5743c7d5886732b2a411c0ed2c5a3b9d 268 Pfam PF02361 Cobalt transport protein 14 236 5.9E-48 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CWR44_RS00645 5743c7d5886732b2a411c0ed2c5a3b9d 268 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 34.109 T 28-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 CWR44_RS04335 b69acb64805c32ad8c7ae48249cb7b76 266 SUPERFAMILY SSF56281 11 238 6.81E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS04335 b69acb64805c32ad8c7ae48249cb7b76 266 Pfam PF00753 Metallo-beta-lactamase superfamily 14 220 1.3E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS04335 b69acb64805c32ad8c7ae48249cb7b76 266 SMART SM00849 15 193 3.5E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS04335 b69acb64805c32ad8c7ae48249cb7b76 266 Gene3D G3DSA:3.60.15.10 9 259 3.2E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS10490 1d0689850fffb5d58914e942b712be88 325 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 151 314 2.9E-40 T 28-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal CWR44_RS10490 1d0689850fffb5d58914e942b712be88 325 Pfam PF06081 Aromatic acid exporter family member 1 8 147 2.4E-43 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CWR44_RS03595 c1249d467100176f21465f3877bb5b9f 535 Pfam PF00488 MutS domain V 351 534 4.0E-29 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR44_RS03595 c1249d467100176f21465f3877bb5b9f 535 Gene3D G3DSA:3.40.50.300 314 535 8.2E-21 T 28-03-2018 CWR44_RS03595 c1249d467100176f21465f3877bb5b9f 535 SUPERFAMILY SSF52540 314 534 1.93E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS03595 c1249d467100176f21465f3877bb5b9f 535 SMART SM00534 347 532 2.4E-11 T 28-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CWR44_RS02025 35a681f705beb9df3240d72a5042fbae 268 SUPERFAMILY SSF54593 8 166 1.01E-35 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS02025 35a681f705beb9df3240d72a5042fbae 268 Gene3D G3DSA:3.10.180.10 2 64 2.2E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS02025 35a681f705beb9df3240d72a5042fbae 268 Gene3D G3DSA:3.10.180.10 65 226 4.4E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS02025 35a681f705beb9df3240d72a5042fbae 268 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 124 2.1E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CWR44_RS02025 35a681f705beb9df3240d72a5042fbae 268 SUPERFAMILY SSF54593 169 245 2.48E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS09230 4b1948de569eed5dd8e3c52f53a4a0d8 70 Gene3D G3DSA:1.10.260.40 2 68 3.0E-5 T 28-03-2018 CWR44_RS09230 4b1948de569eed5dd8e3c52f53a4a0d8 70 SUPERFAMILY SSF47413 6 60 7.74E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS07305 be212cc9ba253afd9388ec023b6b4523 159 Pfam PF01899 Na+/H+ ion antiporter subunit 9 156 3.5E-43 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CWR44_RS07305 be212cc9ba253afd9388ec023b6b4523 159 PIRSF PIRSF019239 1 159 1.7E-45 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CWR44_RS07285 84d0c3ee6613a177fc6a97a235afc789 125 Gene3D G3DSA:3.10.129.10 2 122 2.2E-22 T 28-03-2018 CWR44_RS07285 84d0c3ee6613a177fc6a97a235afc789 125 SUPERFAMILY SSF54637 4 118 3.42E-26 T 28-03-2018 IPR029069 HotDog domain CWR44_RS07285 84d0c3ee6613a177fc6a97a235afc789 125 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 4 118 5.2E-31 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CWR44_RS07285 84d0c3ee6613a177fc6a97a235afc789 125 Pfam PF03061 Thioesterase superfamily 34 111 3.4E-14 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CWR44_RS08920 3fc5c404631b837054776f22916663ed 307 Pfam PF12146 Serine aminopeptidase, S33 29 286 1.8E-49 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CWR44_RS08920 3fc5c404631b837054776f22916663ed 307 Gene3D G3DSA:3.40.50.1820 1 307 2.0E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS08920 3fc5c404631b837054776f22916663ed 307 SUPERFAMILY SSF53474 28 301 1.35E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS07315 2ef3b677e98fce31a621381a6902e226 113 TIGRFAM TIGR00941 2a6301s03: multicomponent Na+:H+ antiporter, MnhC subunit 2 104 2.1E-48 T 28-03-2018 IPR006673 Mnh complex subunit C1 GO:0006812|GO:0008324 CWR44_RS07315 2ef3b677e98fce31a621381a6902e226 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 2.4E-30 T 28-03-2018 CWR44_RS08750 07420a5bd0b4eaf18d62a6049df7b19f 105 Gene3D G3DSA:3.30.1330.30 1 100 2.2E-19 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWR44_RS08750 07420a5bd0b4eaf18d62a6049df7b19f 105 SUPERFAMILY SSF55315 4 100 3.14E-26 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CWR44_RS08750 07420a5bd0b4eaf18d62a6049df7b19f 105 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 6 93 1.7E-14 T 28-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CWR44_RS06340 f0d20c133ab3911b670681fdab1b9b80 629 Pfam PF02687 FtsX-like permease family 85 178 4.1E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR44_RS06340 f0d20c133ab3911b670681fdab1b9b80 629 PIRSF PIRSF018968 1 629 2.5E-96 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWR44_RS02925 d69de35967894ace7010dd34b069e5e6 189 Pfam PF14278 Transcriptional regulator C-terminal region 82 162 1.2E-6 T 28-03-2018 CWR44_RS02925 d69de35967894ace7010dd34b069e5e6 189 Gene3D G3DSA:1.10.10.60 3 46 2.1E-9 T 28-03-2018 CWR44_RS02925 d69de35967894ace7010dd34b069e5e6 189 SUPERFAMILY SSF46689 6 68 9.93E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS02925 d69de35967894ace7010dd34b069e5e6 189 Gene3D G3DSA:1.10.10.60 47 177 5.7E-6 T 28-03-2018 CWR44_RS02925 d69de35967894ace7010dd34b069e5e6 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 56 1.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS12575 7e2ec1f549b9c3511f851790ad892db9 112 Gene3D G3DSA:3.40.190.10 1 109 4.1E-4 T 28-03-2018 CWR44_RS12020 cd2dfe3a735972e9882507289c4d7dcd 352 Pfam PF13303 Phosphotransferase system, EIIC 14 344 1.3E-80 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS10880 7d9f129308f5df99faa5e8de3b03aee9 117 SUPERFAMILY SSF81301 1 112 7.85E-38 T 28-03-2018 CWR44_RS10880 7d9f129308f5df99faa5e8de3b03aee9 117 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 1.7E-34 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CWR44_RS10880 7d9f129308f5df99faa5e8de3b03aee9 117 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 23.325 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CWR44_RS10880 7d9f129308f5df99faa5e8de3b03aee9 117 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 8.3E-25 T 28-03-2018 CWR44_RS10880 7d9f129308f5df99faa5e8de3b03aee9 117 Gene3D G3DSA:3.30.460.10 1 115 8.1E-32 T 28-03-2018 CWR44_RS05560 7527cbbf8136db808f04f763b243d8ab 213 PIRSF PIRSF000441 1 211 1.9E-82 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CWR44_RS05560 7527cbbf8136db808f04f763b243d8ab 213 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 165 4.3E-75 T 28-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CWR44_RS05560 7527cbbf8136db808f04f763b243d8ab 213 Gene3D G3DSA:1.10.3130.10 1 56 2.3E-22 T 28-03-2018 CWR44_RS05560 7527cbbf8136db808f04f763b243d8ab 213 Gene3D G3DSA:2.160.10.10 57 213 2.2E-39 T 28-03-2018 CWR44_RS05560 7527cbbf8136db808f04f763b243d8ab 213 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CWR44_RS05560 7527cbbf8136db808f04f763b243d8ab 213 SUPERFAMILY SSF51161 4 170 2.5E-53 T 28-03-2018 IPR011004 Trimeric LpxA-like CWR44_RS05560 7527cbbf8136db808f04f763b243d8ab 213 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 1.2E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS05560 7527cbbf8136db808f04f763b243d8ab 213 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 120 150 6.2E-8 T 28-03-2018 IPR001451 Hexapeptide repeat CWR44_RS02895 1f9e3c86ced5a8508f21cfffcb9a5d6a 524 Pfam PF03606 C4-dicarboxylate anaerobic carrier 23 520 4.1E-165 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CWR44_RS02170 b8bbdce8f1738575e029731219220ac5 228 Pfam PF04172 LrgB-like family 13 224 1.5E-68 T 28-03-2018 IPR007300 CidB/LrgB family CWR44_RS10375 f91b6fd9aed444393d60cca087070819 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 68 1.4E-22 T 28-03-2018 CWR44_RS10375 f91b6fd9aed444393d60cca087070819 82 Gene3D G3DSA:3.30.70.20 2 82 1.4E-10 T 28-03-2018 CWR44_RS10375 f91b6fd9aed444393d60cca087070819 82 SUPERFAMILY SSF54862 4 73 2.34E-14 T 28-03-2018 CWR44_RS10375 f91b6fd9aed444393d60cca087070819 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 4.4E-8 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CWR44_RS10375 f91b6fd9aed444393d60cca087070819 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 4.4E-8 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CWR44_RS10375 f91b6fd9aed444393d60cca087070819 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 4.4E-8 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CWR44_RS03475 8e1756ae7e1e59af057aa166e44a0620 315 Gene3D G3DSA:3.40.50.970 1 315 5.1E-82 T 28-03-2018 CWR44_RS03475 8e1756ae7e1e59af057aa166e44a0620 315 Pfam PF00676 Dehydrogenase E1 component 12 304 5.6E-89 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CWR44_RS03475 8e1756ae7e1e59af057aa166e44a0620 315 SUPERFAMILY SSF52518 3 314 5.16E-96 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS06185 c2417becf2af983c96b39e16690e5794 79 Pfam PF13061 Protein of unknown function (DUF3923) 5 68 2.9E-18 T 28-03-2018 IPR025037 Protein of unknown function DUF3923 CWR44_RS11080 32699629a684fff2196dc09fe13cba3e 757 Gene3D G3DSA:3.90.1640.10 62 262 2.9E-26 T 28-03-2018 CWR44_RS11080 32699629a684fff2196dc09fe13cba3e 757 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 563 752 6.7E-55 T 28-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal CWR44_RS11080 32699629a684fff2196dc09fe13cba3e 757 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 557 6.9E-181 T 28-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CWR44_RS11080 32699629a684fff2196dc09fe13cba3e 757 Pfam PF01368 DHH family 82 214 5.3E-12 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CWR44_RS11080 32699629a684fff2196dc09fe13cba3e 757 SUPERFAMILY SSF64182 57 441 3.4E-117 T 28-03-2018 CWR44_RS11080 32699629a684fff2196dc09fe13cba3e 757 Pfam PF02272 DHHA1 domain 312 436 6.1E-21 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CWR44_RS05060 e4000d2993c3628aed83634fe5b10b54 856 Hamap MF_01871 UPF0753 protein . 7 856 22.873 T 28-03-2018 IPR018752 Uncharacterised protein family UPF0753 CWR44_RS05060 e4000d2993c3628aed83634fe5b10b54 856 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 12 842 5.7E-251 T 28-03-2018 IPR018752 Uncharacterised protein family UPF0753 CWR44_RS02235 5296d8293fae45436a724c57c3763da7 148 Gene3D G3DSA:3.10.180.10 1 147 7.4E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS02235 5296d8293fae45436a724c57c3763da7 148 SUPERFAMILY SSF54593 3 145 2.08E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS02235 5296d8293fae45436a724c57c3763da7 148 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 138 7.4E-10 T 28-03-2018 IPR028973 PhnB-like CWR44_RS11395 a22e07cfa57c14b0f4479b38e85968c1 229 Gene3D G3DSA:3.60.15.10 1 229 1.8E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS11395 a22e07cfa57c14b0f4479b38e85968c1 229 SUPERFAMILY SSF56281 1 229 2.75E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS11395 a22e07cfa57c14b0f4479b38e85968c1 229 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 229 37.889 T 28-03-2018 IPR022877 Protein of unknown funcion UPF0173 CWR44_RS11395 a22e07cfa57c14b0f4479b38e85968c1 229 SMART SM00849 7 195 3.3E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS11395 a22e07cfa57c14b0f4479b38e85968c1 229 Pfam PF13483 Beta-lactamase superfamily domain 2 195 1.6E-24 T 28-03-2018 CWR44_RS08745 88bb3ff1647e3083bc44229c08b95974 94 SUPERFAMILY SSF64376 4 91 5.36E-25 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CWR44_RS08745 88bb3ff1647e3083bc44229c08b95974 94 Pfam PF04296 Protein of unknown function (DUF448) 9 83 2.2E-22 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CWR44_RS08745 88bb3ff1647e3083bc44229c08b95974 94 Gene3D G3DSA:3.30.1230.10 1 92 1.4E-24 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CWR44_RS04120 1641e456d779d614533eebab77a64dc7 174 Gene3D G3DSA:2.40.30.20 102 159 0.028 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CWR44_RS04120 1641e456d779d614533eebab77a64dc7 174 Gene3D G3DSA:2.30.30.30 45 85 0.035 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CWR44_RS04120 1641e456d779d614533eebab77a64dc7 174 Pfam PF07563 Protein of unknown function (DUF1541) 53 103 3.2E-26 T 28-03-2018 IPR011438 Domain of unknown function DUF1541 CWR44_RS04120 1641e456d779d614533eebab77a64dc7 174 Pfam PF07563 Protein of unknown function (DUF1541) 117 167 1.3E-22 T 28-03-2018 IPR011438 Domain of unknown function DUF1541 CWR44_RS07490 b8abd74fa78d99005542bc19547da28c 552 Gene3D G3DSA:3.10.105.10 295 509 2.6E-43 T 28-03-2018 CWR44_RS07490 b8abd74fa78d99005542bc19547da28c 552 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 458 5.4E-66 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CWR44_RS07490 b8abd74fa78d99005542bc19547da28c 552 PIRSF PIRSF002741 1 540 6.4E-90 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CWR44_RS07490 b8abd74fa78d99005542bc19547da28c 552 Gene3D G3DSA:3.90.76.10 41 201 8.3E-35 T 28-03-2018 CWR44_RS07490 b8abd74fa78d99005542bc19547da28c 552 Gene3D G3DSA:3.40.190.10 202 294 3.1E-17 T 28-03-2018 CWR44_RS07490 b8abd74fa78d99005542bc19547da28c 552 SUPERFAMILY SSF53850 29 529 2.9E-109 T 28-03-2018 CWR44_RS07615 cf84ce8146115e2655dfa3883f7f3fd6 265 SUPERFAMILY SSF103473 8 251 4.32E-9 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS07615 cf84ce8146115e2655dfa3883f7f3fd6 265 Pfam PF03741 Integral membrane protein TerC family 15 215 1.7E-50 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CWR44_RS07615 cf84ce8146115e2655dfa3883f7f3fd6 265 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 257 1.4E-89 T 28-03-2018 IPR022493 Integral membrane YkoY CWR44_RS07615 cf84ce8146115e2655dfa3883f7f3fd6 265 Gene3D G3DSA:1.20.1250.20 4 108 0.0019 T 28-03-2018 CWR44_RS07005 9893fd25f67b690f4b5474b2ef46c8a0 202 SUPERFAMILY SSF55729 20 199 1.13E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS07005 9893fd25f67b690f4b5474b2ef46c8a0 202 Gene3D G3DSA:3.40.630.30 12 202 8.8E-29 T 28-03-2018 CWR44_RS07005 9893fd25f67b690f4b5474b2ef46c8a0 202 Pfam PF00583 Acetyltransferase (GNAT) family 56 181 1.3E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS11685 8e5f30e6d882d31718869abea3e417c4 319 Pfam PF04055 Radical SAM superfamily 50 212 5.0E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CWR44_RS11685 8e5f30e6d882d31718869abea3e417c4 319 SUPERFAMILY SSF102114 4 312 1.24E-54 T 28-03-2018 CWR44_RS11685 8e5f30e6d882d31718869abea3e417c4 319 Pfam PF16199 Radical_SAM C-terminal domain 218 301 7.2E-24 T 28-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CWR44_RS11685 8e5f30e6d882d31718869abea3e417c4 319 Gene3D G3DSA:3.20.20.70 9 269 6.9E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS11685 8e5f30e6d882d31718869abea3e417c4 319 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 13 312 1.7E-134 T 28-03-2018 IPR005911 Protein YhcC-like GO:0051536 CWR44_RS11685 8e5f30e6d882d31718869abea3e417c4 319 SMART SM00729 30 257 2.1E-40 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CWR44_RS12660 6b4cc5a6bbe740ed9a5c698796a28472 321 SUPERFAMILY SSF53613 1 316 7.17E-77 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS12660 6b4cc5a6bbe740ed9a5c698796a28472 321 Gene3D G3DSA:3.40.1190.20 3 321 3.1E-68 T 28-03-2018 IPR029056 Ribokinase-like CWR44_RS12660 6b4cc5a6bbe740ed9a5c698796a28472 321 Pfam PF00294 pfkB family carbohydrate kinase 2 311 2.1E-70 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CWR44_RS12660 6b4cc5a6bbe740ed9a5c698796a28472 321 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 253 266 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CWR44_RS07660 528d0e9d8a05e78c9670a3a410344fed 157 Pfam PF14470 Bacterial PH domain 16 113 6.2E-18 T 28-03-2018 CWR44_RS05610 494cd832e93a05cc76864e16fff08d08 231 Gene3D G3DSA:3.40.50.790 68 148 9.1E-39 T 28-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CWR44_RS05610 494cd832e93a05cc76864e16fff08d08 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 45.021 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CWR44_RS05610 494cd832e93a05cc76864e16fff08d08 231 Gene3D G3DSA:3.30.190.20 149 228 1.3E-21 T 28-03-2018 CWR44_RS05610 494cd832e93a05cc76864e16fff08d08 231 Pfam PF00687 Ribosomal protein L1p/L10e family 32 220 2.8E-55 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CWR44_RS05610 494cd832e93a05cc76864e16fff08d08 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 3.2E-108 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CWR44_RS05610 494cd832e93a05cc76864e16fff08d08 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS05610 494cd832e93a05cc76864e16fff08d08 231 SUPERFAMILY SSF56808 6 226 1.29E-87 T 28-03-2018 IPR023674 Ribosomal protein L1-like CWR44_RS05610 494cd832e93a05cc76864e16fff08d08 231 PIRSF PIRSF002155 1 227 1.3E-84 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CWR44_RS02215 e9832cafca939197951d67c5093abf28 105 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 31 98 3.0E-23 T 28-03-2018 CWR44_RS02215 e9832cafca939197951d67c5093abf28 105 SUPERFAMILY SSF81665 3 68 3.66E-5 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CWR44_RS02215 e9832cafca939197951d67c5093abf28 105 Pfam PF14145 YrhK-like protein 31 84 6.6E-17 T 28-03-2018 IPR025424 YrhK domain CWR44_RS07690 a945c4d3cbc35fc6fe840bbb9387c304 76 Pfam PF05154 TM2 domain 2 52 1.2E-14 T 28-03-2018 IPR007829 TM2 domain CWR44_RS07735 d97c729af1a9cb800c30267b43d40ea0 335 Pfam PF01757 Acyltransferase family 9 309 5.0E-19 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CWR44_RS06005 9eaa2d0bfa33a9a2b3a56de7e585b6f3 358 Pfam PF01019 Gamma-glutamyltranspeptidase 22 342 1.7E-51 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS06005 9eaa2d0bfa33a9a2b3a56de7e585b6f3 358 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 240 255 3.9E-13 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS06005 9eaa2d0bfa33a9a2b3a56de7e585b6f3 358 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 72 88 3.9E-13 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS06005 9eaa2d0bfa33a9a2b3a56de7e585b6f3 358 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 186 204 3.9E-13 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS06005 9eaa2d0bfa33a9a2b3a56de7e585b6f3 358 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 263 280 3.9E-13 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CWR44_RS06005 9eaa2d0bfa33a9a2b3a56de7e585b6f3 358 SUPERFAMILY SSF56235 17 354 2.93E-61 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CWR44_RS05995 2c48526e6ab417cacfa87dd0a60771a7 168 Pfam PF08741 YwhD family 5 166 1.9E-79 T 28-03-2018 IPR014852 Uncharacterised protein YwhD CWR44_RS09565 1de15efb9d818be60145a90ebc90a9c8 115 Gene3D G3DSA:1.10.287.1080 2 93 1.6E-12 T 28-03-2018 CWR44_RS09565 1de15efb9d818be60145a90ebc90a9c8 115 SUPERFAMILY SSF101386 15 99 6.17E-13 T 28-03-2018 CWR44_RS09565 1de15efb9d818be60145a90ebc90a9c8 115 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 43 99 2.9E-6 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CWR44_RS07260 99a2753272213f95b529a0725194c7ce 81 Hamap MF_01542 UPF0349 protein . 1 77 28.804 T 28-03-2018 IPR022916 Protein of unknown function UPF0349 CWR44_RS07260 99a2753272213f95b529a0725194c7ce 81 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 1 76 3.0E-37 T 28-03-2018 CWR44_RS07260 99a2753272213f95b529a0725194c7ce 81 Pfam PF07293 Protein of unknown function (DUF1450) 1 75 3.0E-34 T 28-03-2018 IPR009910 Protein of unknown function DUF1450 CWR44_RS06955 19278ccf678db00dee627d3ca89440da 77 Pfam PF03840 Preprotein translocase SecG subunit 4 74 1.0E-22 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWR44_RS06955 19278ccf678db00dee627d3ca89440da 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 7.0E-13 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWR44_RS06955 19278ccf678db00dee627d3ca89440da 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 7.0E-13 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWR44_RS06955 19278ccf678db00dee627d3ca89440da 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 7.0E-13 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWR44_RS06955 19278ccf678db00dee627d3ca89440da 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 75 9.0E-24 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CWR44_RS01005 5c27e108ae2b89d43132032d69d830df 356 Gene3D G3DSA:3.40.50.720 1 190 2.3E-13 T 28-03-2018 CWR44_RS01005 5c27e108ae2b89d43132032d69d830df 356 SUPERFAMILY SSF48179 188 355 2.21E-41 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CWR44_RS01005 5c27e108ae2b89d43132032d69d830df 356 Gene3D G3DSA:1.10.1040.10 196 352 7.1E-42 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CWR44_RS01005 5c27e108ae2b89d43132032d69d830df 356 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 187 333 4.5E-37 T 28-03-2018 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 CWR44_RS01005 5c27e108ae2b89d43132032d69d830df 356 SUPERFAMILY SSF51735 1 163 3.66E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS05590 ff01dd624122df9d40ddfee300027fd0 47 SUPERFAMILY SSF57829 3 47 5.31E-13 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CWR44_RS05590 ff01dd624122df9d40ddfee300027fd0 47 ProSitePatterns PS00582 Ribosomal protein L33 signature. 16 34 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CWR44_RS05590 ff01dd624122df9d40ddfee300027fd0 47 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 47 1.1E-12 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS05590 ff01dd624122df9d40ddfee300027fd0 47 Pfam PF00471 Ribosomal protein L33 2 47 3.3E-15 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS05590 ff01dd624122df9d40ddfee300027fd0 47 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 47 14.875 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CWR44_RS04485 a48567569e6f1bde2edde16763eccd60 132 Pfam PF11345 Protein of unknown function (DUF3147) 4 111 2.9E-36 T 28-03-2018 IPR021493 Protein of unknown function DUF3147 CWR44_RS03555 7066df075434c18a8106b888cc1db4f2 272 Pfam PF01073 3-beta hydroxysteroid dehydrogenase/isomerase family 3 172 1.1E-11 T 28-03-2018 IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase GO:0003854|GO:0006694|GO:0016616|GO:0055114 CWR44_RS03555 7066df075434c18a8106b888cc1db4f2 272 SUPERFAMILY SSF51735 2 266 3.2E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS03555 7066df075434c18a8106b888cc1db4f2 272 Gene3D G3DSA:3.40.50.720 2 272 1.1E-28 T 28-03-2018 CWR44_RS06235 1450c09213afb639717ad81e19a12623 132 Gene3D G3DSA:3.40.50.620 1 128 1.5E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS06235 1450c09213afb639717ad81e19a12623 132 SUPERFAMILY SSF52374 1 125 2.82E-33 T 28-03-2018 CWR44_RS06235 1450c09213afb639717ad81e19a12623 132 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 67 1.2E-22 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR44_RS06235 1450c09213afb639717ad81e19a12623 132 Pfam PF01467 Cytidylyltransferase-like 5 124 8.5E-23 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CWR44_RS06235 1450c09213afb639717ad81e19a12623 132 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 9.6E-60 T 28-03-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 CWR44_RS04240 9eb5533f32fd606c0f9aa7ae68d3f4af 538 Gene3D G3DSA:3.40.50.300 188 399 2.1E-12 T 28-03-2018 CWR44_RS04240 9eb5533f32fd606c0f9aa7ae68d3f4af 538 SUPERFAMILY SSF52540 192 369 1.13E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS09455 27fbdb45d27eeb48c6872c2b7f84f12f 270 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 2 247 2.2E-70 T 28-03-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 CWR44_RS09455 27fbdb45d27eeb48c6872c2b7f84f12f 270 Pfam PF03837 RecT family 57 255 3.1E-51 T 28-03-2018 IPR018330 RecT family GO:0003677|GO:0006259 CWR44_RS06725 a932d6f58fd91dbeebe1ebcd50a0608c 104 SUPERFAMILY SSF161219 5 90 4.45E-20 T 28-03-2018 CWR44_RS06725 a932d6f58fd91dbeebe1ebcd50a0608c 104 Pfam PF05495 CHY zinc finger 15 88 1.6E-13 T 28-03-2018 IPR008913 Zinc finger, CHY-type GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 CWR44_RS06725 a932d6f58fd91dbeebe1ebcd50a0608c 104 PIRSF PIRSF017292 1 104 3.9E-47 T 28-03-2018 IPR016694 Protein of unknown function UCP017292, zinc finger, CHY-type CWR44_RS05320 0aec02c04a55e11980c863360d1ddb4e 100 Pfam PF04026 SpoVG 1 81 4.6E-36 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CWR44_RS05320 0aec02c04a55e11980c863360d1ddb4e 100 Gene3D G3DSA:3.30.1120.40 1 83 2.0E-36 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CWR44_RS05320 0aec02c04a55e11980c863360d1ddb4e 100 SUPERFAMILY SSF160537 1 83 7.85E-33 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CWR44_RS05320 0aec02c04a55e11980c863360d1ddb4e 100 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 28.997 T 28-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CWR44_RS10975 2308e915e78b4ef6c1a69a4fbaee9e9d 104 Hamap MF_01448 UPF0473 protein . 17 104 19.321 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CWR44_RS10975 2308e915e78b4ef6c1a69a4fbaee9e9d 104 Pfam PF06949 Protein of unknown function (DUF1292) 26 103 2.5E-12 T 28-03-2018 IPR009711 Uncharacterised protein family UPF0473 CWR44_RS04945 8f3a4405b0ff458d38fb9f2a94fe86fc 71 SUPERFAMILY SSF47413 5 68 1.26E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS04945 8f3a4405b0ff458d38fb9f2a94fe86fc 71 Gene3D G3DSA:1.10.260.40 2 71 5.8E-12 T 28-03-2018 CWR44_RS04945 8f3a4405b0ff458d38fb9f2a94fe86fc 71 SMART SM00530 7 62 1.8E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS04945 8f3a4405b0ff458d38fb9f2a94fe86fc 71 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 15 67 4.4E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CWR44_RS01460 2b8f48bf7c397bbe13e5c09a50121ff7 119 Pfam PF11337 Protein of unknown function (DUF3139) 10 83 3.0E-20 T 28-03-2018 IPR021486 Protein of unknown function DUF3139 CWR44_RS00115 f3b92aa8a783300ec4bae4edf90bea0c 132 SUPERFAMILY SSF50249 1 108 1.37E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS00115 f3b92aa8a783300ec4bae4edf90bea0c 132 Pfam PF00436 Single-strand binding protein family 2 101 2.3E-22 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CWR44_RS00115 f3b92aa8a783300ec4bae4edf90bea0c 132 Gene3D G3DSA:2.40.50.140 1 109 9.7E-26 T 28-03-2018 CWR44_RS00115 f3b92aa8a783300ec4bae4edf90bea0c 132 Hamap MF_00984 Single-stranded DNA-binding protein. 2 105 25.594 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWR44_RS00115 f3b92aa8a783300ec4bae4edf90bea0c 132 PIRSF PIRSF002070 1 125 9.5E-27 T 28-03-2018 CWR44_RS00115 f3b92aa8a783300ec4bae4edf90bea0c 132 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 109 2.3E-18 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CWR44_RS01295 09ed2b1c70000ce177300193cf92c896 221 SMART SM00382 31 218 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS01295 09ed2b1c70000ce177300193cf92c896 221 SUPERFAMILY SSF52540 3 219 2.34E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS01295 09ed2b1c70000ce177300193cf92c896 221 Pfam PF00005 ABC transporter 22 170 1.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS01295 09ed2b1c70000ce177300193cf92c896 221 Gene3D G3DSA:3.40.50.300 1 220 4.4E-65 T 28-03-2018 CWR44_RS00955 af04a8604a0ec1c0f949259ae8e8bd48 315 SUPERFAMILY SSF53590 3 309 7.85E-85 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CWR44_RS00955 af04a8604a0ec1c0f949259ae8e8bd48 315 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 302 1.2E-51 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CWR44_RS00955 af04a8604a0ec1c0f949259ae8e8bd48 315 Gene3D G3DSA:3.90.245.10 1 313 2.1E-65 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CWR44_RS02345 1d1452c49f985f1f6f50ea983aa57dd4 222 SUPERFAMILY SSF51735 2 177 1.97E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS02345 1d1452c49f985f1f6f50ea983aa57dd4 222 Gene3D G3DSA:3.40.50.720 1 183 9.2E-10 T 28-03-2018 CWR44_RS02345 1d1452c49f985f1f6f50ea983aa57dd4 222 Pfam PF05368 NmrA-like family 3 174 5.4E-26 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CWR44_RS02185 910db77d49caf9d9feabb7c378c758a2 71 SUPERFAMILY SSF140652 2 70 1.7E-18 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS02185 910db77d49caf9d9feabb7c378c758a2 71 Gene3D G3DSA:1.10.150.260 1 67 1.4E-17 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS02185 910db77d49caf9d9feabb7c378c758a2 71 Pfam PF06855 YozE SAM-like fold 2 66 1.0E-17 T 28-03-2018 IPR023089 YozE SAM-like domain CWR44_RS07100 41da01fa3d7cdcc4787b4cc76b7b7db6 128 Gene3D G3DSA:3.40.1360.20 1 118 8.6E-15 T 28-03-2018 CWR44_RS07100 41da01fa3d7cdcc4787b4cc76b7b7db6 128 SMART SM00493 5 79 4.3E-9 T 28-03-2018 IPR006171 TOPRIM domain CWR44_RS07100 41da01fa3d7cdcc4787b4cc76b7b7db6 128 SUPERFAMILY SSF110455 2 111 1.96E-33 T 28-03-2018 CWR44_RS09835 1aedceb7804875fd2a48cd200508041b 62 Pfam PF01361 Tautomerase enzyme 2 60 9.0E-24 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CWR44_RS09835 1aedceb7804875fd2a48cd200508041b 62 SUPERFAMILY SSF55331 2 60 4.84E-18 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CWR44_RS09835 1aedceb7804875fd2a48cd200508041b 62 Gene3D G3DSA:3.30.429.10 2 55 8.1E-17 T 28-03-2018 CWR44_RS09835 1aedceb7804875fd2a48cd200508041b 62 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 60 1.6E-24 T 28-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CWR44_RS04005 eaa098bacccd7c11b21512ed5760f8b2 334 SMART SM00829 17 329 3.1E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CWR44_RS04005 eaa098bacccd7c11b21512ed5760f8b2 334 Pfam PF16884 N-terminal domain of oxidoreductase 5 110 4.2E-34 T 28-03-2018 CWR44_RS04005 eaa098bacccd7c11b21512ed5760f8b2 334 Pfam PF00107 Zinc-binding dehydrogenase 156 290 6.1E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CWR44_RS04005 eaa098bacccd7c11b21512ed5760f8b2 334 SUPERFAMILY SSF51735 122 296 9.41E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS04005 eaa098bacccd7c11b21512ed5760f8b2 334 SUPERFAMILY SSF50129 2 141 7.07E-36 T 28-03-2018 IPR011032 GroES-like CWR44_RS04005 eaa098bacccd7c11b21512ed5760f8b2 334 Gene3D G3DSA:3.90.180.10 1 146 4.8E-35 T 28-03-2018 CWR44_RS04005 eaa098bacccd7c11b21512ed5760f8b2 334 Gene3D G3DSA:3.40.50.720 147 273 1.8E-25 T 28-03-2018 CWR44_RS01300 71e2eaaa482176278f401a511e77dd24 351 Pfam PF02687 FtsX-like permease family 259 343 9.3E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR44_RS01300 71e2eaaa482176278f401a511e77dd24 351 Pfam PF12704 MacB-like periplasmic core domain 17 174 1.3E-6 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CWR44_RS09120 518d203d76e35d55cf64f3de9c6c0816 563 Gene3D G3DSA:3.40.50.300 116 240 0.0015 T 28-03-2018 CWR44_RS09120 518d203d76e35d55cf64f3de9c6c0816 563 Pfam PF03354 Phage Terminase 82 539 2.8E-78 T 28-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CWR44_RS11710 24993ce55666996b2cbca4cc3e6d0b6c 275 Pfam PF12146 Serine aminopeptidase, S33 9 244 8.2E-43 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CWR44_RS11710 24993ce55666996b2cbca4cc3e6d0b6c 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 38 53 4.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS11710 24993ce55666996b2cbca4cc3e6d0b6c 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 4.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS11710 24993ce55666996b2cbca4cc3e6d0b6c 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 4.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CWR44_RS11710 24993ce55666996b2cbca4cc3e6d0b6c 275 SUPERFAMILY SSF53474 8 258 8.54E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS11710 24993ce55666996b2cbca4cc3e6d0b6c 275 Gene3D G3DSA:3.40.50.1820 2 259 1.7E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS04900 7c7090a425e49e3cad348f0367d8fa4c 135 ProDom PD458455 UPF0355 MW0363 SE2351 MRSA252 SSP2326 SH2586 SA0372 SAV0387 SACOL0457 SERP0066 1 135 1.0E-72 T 28-03-2018 CWR44_RS04900 7c7090a425e49e3cad348f0367d8fa4c 135 Pfam PF11181 Heat induced stress protein YflT 6 100 8.7E-16 T 28-03-2018 IPR025889 General stress protein 17M-like domain CWR44_RS13185 8b1d2cf249a26f332c688b2ae8ea2516 175 SUPERFAMILY SSF55729 4 170 8.14E-34 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS13185 8b1d2cf249a26f332c688b2ae8ea2516 175 Gene3D G3DSA:3.40.630.30 2 175 2.8E-27 T 28-03-2018 CWR44_RS13185 8b1d2cf249a26f332c688b2ae8ea2516 175 Pfam PF13420 Acetyltransferase (GNAT) domain 8 163 3.4E-15 T 28-03-2018 CWR44_RS10920 387ca5bc3635d12a6535b7874446909e 418 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 180 186 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CWR44_RS10920 387ca5bc3635d12a6535b7874446909e 418 Pfam PF01566 Natural resistance-associated macrophage protein 60 385 2.1E-25 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CWR44_RS01370 d36c5846ef451c4885e3882e120b1a60 287 Pfam PF09375 Imelysin 48 282 5.7E-36 T 28-03-2018 IPR018976 Peptidase M75, Imelysin CWR44_RS01370 d36c5846ef451c4885e3882e120b1a60 287 Gene3D G3DSA:3.40.190.10 1 164 8.7E-5 T 28-03-2018 CWR44_RS13110 4e0f79b18a5a7023348ac5e31994a80b 514 Gene3D G3DSA:1.20.1250.20 268 514 1.5E-26 T 28-03-2018 CWR44_RS13110 4e0f79b18a5a7023348ac5e31994a80b 514 Pfam PF07690 Major Facilitator Superfamily 25 417 3.0E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS13110 4e0f79b18a5a7023348ac5e31994a80b 514 Gene3D G3DSA:1.20.1250.20 9 209 2.9E-38 T 28-03-2018 CWR44_RS13110 4e0f79b18a5a7023348ac5e31994a80b 514 ProSitePatterns PS00216 Sugar transport proteins signature 1. 74 90 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CWR44_RS13110 4e0f79b18a5a7023348ac5e31994a80b 514 SUPERFAMILY SSF103473 478 509 1.06E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS13110 4e0f79b18a5a7023348ac5e31994a80b 514 SUPERFAMILY SSF103473 257 427 1.06E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS13110 4e0f79b18a5a7023348ac5e31994a80b 514 SUPERFAMILY SSF103473 11 204 1.06E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS03040 d3cc6af076b1a769e9cd43c1c4535705 266 Gene3D G3DSA:1.10.3720.10 17 266 7.3E-26 T 28-03-2018 CWR44_RS03040 d3cc6af076b1a769e9cd43c1c4535705 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 255 2.6E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03040 d3cc6af076b1a769e9cd43c1c4535705 266 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 19 265 5.1E-92 T 28-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CWR44_RS03040 d3cc6af076b1a769e9cd43c1c4535705 266 SUPERFAMILY SSF161098 71 258 1.83E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS03585 6a7b3db91cb0de7db2a8a8dcf8e1254b 429 PRINTS PR00758 Arsenical pump membrane protein signature 145 169 3.8E-112 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03585 6a7b3db91cb0de7db2a8a8dcf8e1254b 429 PRINTS PR00758 Arsenical pump membrane protein signature 218 243 3.8E-112 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03585 6a7b3db91cb0de7db2a8a8dcf8e1254b 429 PRINTS PR00758 Arsenical pump membrane protein signature 279 303 3.8E-112 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03585 6a7b3db91cb0de7db2a8a8dcf8e1254b 429 PRINTS PR00758 Arsenical pump membrane protein signature 178 201 3.8E-112 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03585 6a7b3db91cb0de7db2a8a8dcf8e1254b 429 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 3.8E-112 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03585 6a7b3db91cb0de7db2a8a8dcf8e1254b 429 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 3.8E-112 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03585 6a7b3db91cb0de7db2a8a8dcf8e1254b 429 PRINTS PR00758 Arsenical pump membrane protein signature 398 422 3.8E-112 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03585 6a7b3db91cb0de7db2a8a8dcf8e1254b 429 PRINTS PR00758 Arsenical pump membrane protein signature 365 390 3.8E-112 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03585 6a7b3db91cb0de7db2a8a8dcf8e1254b 429 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 428 1.6E-216 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS03585 6a7b3db91cb0de7db2a8a8dcf8e1254b 429 Pfam PF02040 Arsenical pump membrane protein 4 425 1.7E-186 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CWR44_RS04130 8dab7ded1d7b9d53f9413527b5f6e761 252 Pfam PF01925 Sulfite exporter TauE/SafE 11 247 2.4E-38 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CWR44_RS01990 10504e614d6698faf6dad89830802030 197 SUPERFAMILY SSF53474 3 195 8.65E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS01990 10504e614d6698faf6dad89830802030 197 Pfam PF02230 Phospholipase/Carboxylesterase 3 195 9.3E-11 T 28-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CWR44_RS01990 10504e614d6698faf6dad89830802030 197 Gene3D G3DSA:3.40.50.1820 1 195 1.4E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS05850 4d433c4f543bb09d8a8666a9d57a37e7 210 SMART SM00934 2 203 5.9E-37 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS05850 4d433c4f543bb09d8a8666a9d57a37e7 210 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 2 207 5.4E-88 T 28-03-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 CWR44_RS05850 4d433c4f543bb09d8a8666a9d57a37e7 210 SUPERFAMILY SSF51366 3 208 4.71E-40 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR44_RS05850 4d433c4f543bb09d8a8666a9d57a37e7 210 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 202 1.3E-29 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS05850 4d433c4f543bb09d8a8666a9d57a37e7 210 Gene3D G3DSA:3.20.20.70 1 208 1.6E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS11925 c975a7611b19260d5ae8c7cb90456f08 185 Pfam PF11667 Putative zincin peptidase 59 163 2.6E-18 T 28-03-2018 IPR021683 Putative zincin peptidase CWR44_RS07730 3c636a59dfe891ef20fa07ad233148be 387 SUPERFAMILY SSF53383 23 382 2.26E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS07730 3c636a59dfe891ef20fa07ad233148be 387 Pfam PF00155 Aminotransferase class I and II 29 377 4.5E-57 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR44_RS07730 3c636a59dfe891ef20fa07ad233148be 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 229 242 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CWR44_RS07730 3c636a59dfe891ef20fa07ad233148be 387 Gene3D G3DSA:3.90.1150.10 271 385 1.8E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS07730 3c636a59dfe891ef20fa07ad233148be 387 Gene3D G3DSA:3.40.640.10 44 270 1.4E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS03200 707f8d835b2286a9bc564496cc398b34 220 Pfam PF02517 CAAX protease self-immunity 125 211 6.9E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR44_RS09920 5f9b3bf51717b2399901ec66bf163cc0 603 SUPERFAMILY SSF55486 58 599 8.38E-108 T 28-03-2018 CWR44_RS09920 5f9b3bf51717b2399901ec66bf163cc0 603 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 8 594 8.7E-200 T 28-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CWR44_RS09920 5f9b3bf51717b2399901ec66bf163cc0 603 Gene3D G3DSA:1.10.1370.10 78 581 2.5E-32 T 28-03-2018 CWR44_RS09920 5f9b3bf51717b2399901ec66bf163cc0 603 Pfam PF08439 Oligopeptidase F 115 180 5.1E-14 T 28-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CWR44_RS09920 5f9b3bf51717b2399901ec66bf163cc0 603 Pfam PF01432 Peptidase family M3 203 581 1.5E-36 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CWR44_RS03955 5f9e79a0ce0d1d6895f7fd5152cfd6be 174 Pfam PF11667 Putative zincin peptidase 59 162 9.8E-24 T 28-03-2018 IPR021683 Putative zincin peptidase CWR44_RS08465 44cd11c5ccdb29b4c02e5ecce53d2314 399 SUPERFAMILY SSF102645 186 398 2.35E-73 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CWR44_RS08465 44cd11c5ccdb29b4c02e5ecce53d2314 399 Pfam PF02441 Flavoprotein 2 174 4.0E-45 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWR44_RS08465 44cd11c5ccdb29b4c02e5ecce53d2314 399 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 394 4.8E-142 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CWR44_RS08465 44cd11c5ccdb29b4c02e5ecce53d2314 399 Gene3D G3DSA:3.40.50.10300 183 399 3.4E-67 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CWR44_RS08465 44cd11c5ccdb29b4c02e5ecce53d2314 399 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 188 368 2.3E-71 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CWR44_RS08465 44cd11c5ccdb29b4c02e5ecce53d2314 399 SUPERFAMILY SSF52507 2 176 1.83E-57 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWR44_RS08465 44cd11c5ccdb29b4c02e5ecce53d2314 399 Gene3D G3DSA:3.40.50.1950 1 182 1.2E-52 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CWR44_RS06205 efecd37fae73d0ab156bcb57354531cd 247 Pfam PF13398 Peptidase M50B-like 19 241 3.5E-40 T 28-03-2018 CWR44_RS10030 8554eb500b00cb3c5a9c3b6541d447c2 447 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 9 421 1.2E-141 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWR44_RS10030 8554eb500b00cb3c5a9c3b6541d447c2 447 Pfam PF05525 Branched-chain amino acid transport protein 2 436 3.9E-139 T 28-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CWR44_RS01670 a5206fdc80811c7cc115cfc367493525 735 Pfam PF00999 Sodium/hydrogen exchanger family 8 421 5.7E-52 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CWR44_RS10665 927a9559a2a9fe0e9140dba211399f55 67 SUPERFAMILY SSF158379 5 65 9.29E-21 T 28-03-2018 IPR023164 YqgQ-like domain CWR44_RS10665 927a9559a2a9fe0e9140dba211399f55 67 Gene3D G3DSA:1.10.287.760 5 67 3.0E-23 T 28-03-2018 IPR023164 YqgQ-like domain CWR44_RS10665 927a9559a2a9fe0e9140dba211399f55 67 Pfam PF06014 Bacterial protein of unknown function (DUF910) 5 64 1.6E-22 T 28-03-2018 IPR009256 Protein of unknown function DUF910 CWR44_RS09070 b8b2ad00408ca7669812d9e89931e605 226 Gene3D G3DSA:1.10.10.10 157 221 2.1E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS09070 b8b2ad00408ca7669812d9e89931e605 226 SMART SM00497 167 220 2.3E-5 T 28-03-2018 IPR003647 Intron encoded nuclease repeat CWR44_RS08265 ae827234fadae1bb7570984d25b8551b 44 Pfam PF05480 Staphylococcus haemolytic protein 1 43 5.4E-23 T 28-03-2018 IPR008846 Staphylococcal hemolytic protein family GO:0009405 CWR44_RS08255 ae827234fadae1bb7570984d25b8551b 44 Pfam PF05480 Staphylococcus haemolytic protein 1 43 5.4E-23 T 28-03-2018 IPR008846 Staphylococcal hemolytic protein family GO:0009405 CWR44_RS06900 046001d6c06a1c374b80de79b11ea456 299 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 219 8.9E-18 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CWR44_RS06900 046001d6c06a1c374b80de79b11ea456 299 Gene3D G3DSA:3.40.50.720 2 299 1.0E-27 T 28-03-2018 CWR44_RS06900 046001d6c06a1c374b80de79b11ea456 299 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 5 292 5.7E-103 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 CWR44_RS06900 046001d6c06a1c374b80de79b11ea456 299 Pfam PF08338 Domain of unknown function (DUF1731) 250 296 3.0E-17 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 CWR44_RS06900 046001d6c06a1c374b80de79b11ea456 299 SUPERFAMILY SSF51735 4 296 6.18E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS01060 9818b304b7b71f6d1a06f0938a335630 315 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 89 234 1.2E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR44_RS01060 9818b304b7b71f6d1a06f0938a335630 315 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 89 234 4.6E-47 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CWR44_RS00530 099e42f649e8814dcaa9c3bc9a67996f 355 SUPERFAMILY SSF51419 7 230 5.23E-24 T 28-03-2018 IPR029066 PLP-binding barrel CWR44_RS00530 099e42f649e8814dcaa9c3bc9a67996f 355 Pfam PF01168 Alanine racemase, N-terminal domain 6 220 1.7E-20 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CWR44_RS00530 099e42f649e8814dcaa9c3bc9a67996f 355 Gene3D G3DSA:3.20.20.10 1 233 1.1E-23 T 28-03-2018 IPR029066 PLP-binding barrel CWR44_RS03155 8ed8c04bf78ecc9b92e88db89d25757f 458 SUPERFAMILY SSF103473 6 194 4.45E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS03155 8ed8c04bf78ecc9b92e88db89d25757f 458 SUPERFAMILY SSF103473 247 456 4.45E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS03155 8ed8c04bf78ecc9b92e88db89d25757f 458 Pfam PF07690 Major Facilitator Superfamily 20 409 6.4E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS03155 8ed8c04bf78ecc9b92e88db89d25757f 458 Gene3D G3DSA:1.20.1250.20 257 457 2.1E-22 T 28-03-2018 CWR44_RS03155 8ed8c04bf78ecc9b92e88db89d25757f 458 Gene3D G3DSA:1.20.1250.20 2 197 2.3E-24 T 28-03-2018 CWR44_RS02805 97b92b952af3db0d613d8790f95bb7e6 199 SUPERFAMILY SSF88723 9 131 2.75E-5 T 28-03-2018 IPR029060 PIN domain-like CWR44_RS02805 97b92b952af3db0d613d8790f95bb7e6 199 Gene3D G3DSA:3.40.50.1010 10 143 0.0019 T 28-03-2018 IPR029060 PIN domain-like CWR44_RS03535 1b59a22c711b842e30108db0240928fa 567 Gene3D G3DSA:3.40.50.300 223 482 2.4E-8 T 28-03-2018 CWR44_RS03535 1b59a22c711b842e30108db0240928fa 567 Pfam PF09818 Predicted ATPase of the ABC class 6 450 3.4E-190 T 28-03-2018 IPR019195 ABC transporter, ATPase, putative CWR44_RS04850 a6d15feb4322f8022cfa0ec68a2bf4cc 209 PIRSF PIRSF006324 1 208 5.5E-48 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CWR44_RS04850 a6d15feb4322f8022cfa0ec68a2bf4cc 209 Pfam PF01810 LysE type translocator 14 206 4.3E-36 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CWR44_RS04775 d840569d9868826ac15f163ace64524f 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS04775 d840569d9868826ac15f163ace64524f 497 Gene3D G3DSA:3.40.309.10 273 471 3.9E-69 T 28-03-2018 CWR44_RS04775 d840569d9868826ac15f163ace64524f 497 Gene3D G3DSA:3.40.605.10 3 272 1.4E-91 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS04775 d840569d9868826ac15f163ace64524f 497 SUPERFAMILY SSF53720 9 490 2.88E-158 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CWR44_RS04775 d840569d9868826ac15f163ace64524f 497 Pfam PF00171 Aldehyde dehydrogenase family 24 485 2.1E-168 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CWR44_RS04775 d840569d9868826ac15f163ace64524f 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CWR44_RS03660 132ec0b12d695ef5a92089c5f7d36ead 127 PIRSF PIRSF006246 1 126 5.8E-55 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CWR44_RS03660 132ec0b12d695ef5a92089c5f7d36ead 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 120 4.2E-53 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CWR44_RS03660 132ec0b12d695ef5a92089c5f7d36ead 127 Pfam PF02261 Aspartate decarboxylase 1 114 1.1E-50 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CWR44_RS03660 132ec0b12d695ef5a92089c5f7d36ead 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 2.0E-37 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CWR44_RS03660 132ec0b12d695ef5a92089c5f7d36ead 127 Gene3D G3DSA:2.40.40.20 1 117 2.9E-52 T 28-03-2018 CWR44_RS03660 132ec0b12d695ef5a92089c5f7d36ead 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 69.298 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CWR44_RS03660 132ec0b12d695ef5a92089c5f7d36ead 127 SUPERFAMILY SSF50692 1 120 1.49E-48 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CWR44_RS09030 e65e31fe0ed66ff5a6f6b8156e377435 119 Gene3D G3DSA:1.10.8.200 5 66 9.9E-13 T 28-03-2018 CWR44_RS11540 5a6e8539cdbaf29fc8e5e94c99be27e6 210 PIRSF PIRSF021278 2 210 1.5E-95 T 28-03-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 CWR44_RS11540 5a6e8539cdbaf29fc8e5e94c99be27e6 210 Gene3D G3DSA:3.40.630.30 1 210 1.0E-43 T 28-03-2018 CWR44_RS11540 5a6e8539cdbaf29fc8e5e94c99be27e6 210 SUPERFAMILY SSF55729 42 122 5.13E-7 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS05675 dbdfbbaa6770f97afe1413ff35b5dec7 396 Pfam PF00155 Aminotransferase class I and II 42 383 3.0E-69 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CWR44_RS05675 dbdfbbaa6770f97afe1413ff35b5dec7 396 Gene3D G3DSA:3.40.640.10 47 292 3.8E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CWR44_RS05675 dbdfbbaa6770f97afe1413ff35b5dec7 396 SUPERFAMILY SSF53383 6 394 2.02E-111 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CWR44_RS05675 dbdfbbaa6770f97afe1413ff35b5dec7 396 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 240 249 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CWR44_RS05675 dbdfbbaa6770f97afe1413ff35b5dec7 396 Gene3D G3DSA:3.90.1150.10 293 393 7.9E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CWR44_RS05675 dbdfbbaa6770f97afe1413ff35b5dec7 396 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 9 394 1.1E-203 T 28-03-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type CWR44_RS04880 f9377450c0a42334b8ae80540e799301 251 Gene3D G3DSA:3.40.109.10 2 251 2.4E-51 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR44_RS04880 f9377450c0a42334b8ae80540e799301 251 Pfam PF00881 Nitroreductase family 10 164 2.0E-17 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CWR44_RS04880 f9377450c0a42334b8ae80540e799301 251 PIRSF PIRSF005426 1 251 2.3E-83 T 28-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 CWR44_RS04880 f9377450c0a42334b8ae80540e799301 251 SUPERFAMILY SSF55469 5 250 1.13E-62 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CWR44_RS12365 fe90b4fa98b81821061ddb90bf12e927 182 Pfam PF11667 Putative zincin peptidase 57 150 1.2E-17 T 28-03-2018 IPR021683 Putative zincin peptidase CWR44_RS10495 4b4143acc52be7ba1cfef7a4376bd6b3 145 Pfam PF06491 Disulphide isomerase 8 142 4.6E-60 T 28-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CWR44_RS10495 4b4143acc52be7ba1cfef7a4376bd6b3 145 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 142 2.3E-60 T 28-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CWR44_RS05755 968c1998833a86392ad67ba80e93afaf 205 Pfam PF01712 Deoxynucleoside kinase 6 198 3.2E-46 T 28-03-2018 IPR031314 Deoxynucleoside kinase domain CWR44_RS05755 968c1998833a86392ad67ba80e93afaf 205 Gene3D G3DSA:3.40.50.300 1 198 6.4E-36 T 28-03-2018 CWR44_RS05755 968c1998833a86392ad67ba80e93afaf 205 SUPERFAMILY SSF52540 1 199 1.94E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS05755 968c1998833a86392ad67ba80e93afaf 205 PIRSF PIRSF000705 1 205 3.0E-60 T 28-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CWR44_RS12485 d15c94bce898c7ee7360d51041cc66a6 344 Gene3D G3DSA:2.130.10.10 10 343 5.3E-30 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CWR44_RS12485 d15c94bce898c7ee7360d51041cc66a6 344 SUPERFAMILY SSF51004 13 343 7.59E-33 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CWR44_RS12485 d15c94bce898c7ee7360d51041cc66a6 344 Pfam PF10282 Lactonase, 7-bladed beta-propeller 5 343 3.2E-102 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CWR44_RS09645 9c56c70a9f8d9369281531425a625dbe 560 Pfam PF03496 ADP-ribosyltransferase exoenzyme 387 540 7.4E-25 T 28-03-2018 IPR003540 ADP ribosyltransferase GO:0005576|GO:0009405 CWR44_RS09645 9c56c70a9f8d9369281531425a625dbe 560 Pfam PF06152 Phage minor capsid protein 2 23 310 9.4E-16 T 28-03-2018 IPR009319 Bacteriophage A118, Gp4, minor capsid GO:0005198|GO:0019028 CWR44_RS09645 9c56c70a9f8d9369281531425a625dbe 560 SUPERFAMILY SSF56399 371 555 1.12E-27 T 28-03-2018 CWR44_RS09645 9c56c70a9f8d9369281531425a625dbe 560 Gene3D G3DSA:3.90.176.10 371 559 2.6E-31 T 28-03-2018 CWR44_RS04030 0dba27d4971fc0b1aa0409a003a762cd 99 Pfam PF04650 YSIRK type signal peptide 14 39 2.3E-12 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS04030 0dba27d4971fc0b1aa0409a003a762cd 99 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 9 51 1.1E-15 T 28-03-2018 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 CWR44_RS09205 83c7d118c02f5a23101166814a483439 425 Gene3D G3DSA:1.20.120.20 137 281 2.1E-4 T 28-03-2018 CWR44_RS09205 83c7d118c02f5a23101166814a483439 425 Pfam PF10651 Domain of unknown function (DUF2479) 3 139 2.7E-25 T 28-03-2018 IPR018913 Domain of unknown function DUF2479 CWR44_RS10025 42a2e56e89a4f99183ebbb9648428d0f 389 PIRSF PIRSF026508 4 389 4.1E-118 T 28-03-2018 IPR008863 Toxic anion resistance CWR44_RS10025 42a2e56e89a4f99183ebbb9648428d0f 389 Pfam PF05816 Toxic anion resistance protein (TelA) 55 384 4.0E-121 T 28-03-2018 IPR008863 Toxic anion resistance CWR44_RS01470 c165ea48fa44dcbf20430acc4b5f5227 138 Gene3D G3DSA:2.60.40.790 2 138 8.7E-26 T 28-03-2018 IPR008978 HSP20-like chaperone CWR44_RS01470 c165ea48fa44dcbf20430acc4b5f5227 138 Pfam PF00011 Hsp20/alpha crystallin family 40 137 1.0E-16 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CWR44_RS01470 c165ea48fa44dcbf20430acc4b5f5227 138 SUPERFAMILY SSF49764 27 136 3.1E-23 T 28-03-2018 IPR008978 HSP20-like chaperone CWR44_RS02585 0a9d4b97b060a6bc184fb772106ac63a 263 SUPERFAMILY SSF54001 149 262 7.75E-19 T 28-03-2018 CWR44_RS02585 0a9d4b97b060a6bc184fb772106ac63a 263 Pfam PF05257 CHAP domain 162 238 3.9E-14 T 28-03-2018 IPR007921 CHAP domain CWR44_RS01760 b2767dffb8927713a16de05960163730 199 PIRSF PIRSF021308 1 199 1.2E-85 T 28-03-2018 IPR016786 Uncharacterised protein YdeI, bacterial CWR44_RS01760 b2767dffb8927713a16de05960163730 199 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 135 193 1.2E-19 T 28-03-2018 CWR44_RS01760 b2767dffb8927713a16de05960163730 199 Pfam PF08818 Domain of unknown function (DU1801) 20 117 2.3E-14 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CWR44_RS01760 b2767dffb8927713a16de05960163730 199 SUPERFAMILY SSF159888 11 128 5.1E-20 T 28-03-2018 CWR44_RS09000 41e637e8c43408ddb02bebcfb9cb5f9f 161 Pfam PF05565 Siphovirus Gp157 4 161 3.1E-50 T 28-03-2018 IPR008840 Siphovirus Gp157 CWR44_RS09000 41e637e8c43408ddb02bebcfb9cb5f9f 161 Gene3D G3DSA:1.20.1170.10 4 130 4.0E-5 T 28-03-2018 CWR44_RS02380 91905787da039055a7d656e2bd55cc85 238 Gene3D G3DSA:3.40.50.620 48 166 3.7E-4 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CWR44_RS02380 91905787da039055a7d656e2bd55cc85 238 Pfam PF02677 Uncharacterized BCR, COG1636 38 217 1.0E-61 T 28-03-2018 IPR003828 Probable epoxyqueuosine reductase QueH CWR44_RS00290 93fd1db828bc792cd329338f17cf9bac 397 SUPERFAMILY SSF56059 126 333 3.89E-25 T 28-03-2018 CWR44_RS00290 93fd1db828bc792cd329338f17cf9bac 397 Gene3D G3DSA:3.30.470.20 123 324 5.8E-20 T 28-03-2018 CWR44_RS00290 93fd1db828bc792cd329338f17cf9bac 397 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 153 227 4.0E-4 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CWR44_RS01500 b4b5330704ad3c8e37345654b48ee33c 196 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 58 178 1.6E-18 T 28-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 CWR44_RS01500 b4b5330704ad3c8e37345654b48ee33c 196 Gene3D G3DSA:1.10.3480.10 15 192 1.7E-16 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CWR44_RS01500 b4b5330704ad3c8e37345654b48ee33c 196 SUPERFAMILY SSF89155 45 183 9.55E-19 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CWR44_RS06275 3c2f8c7f5a19c01bb3ba8c3196313dbd 334 Gene3D G3DSA:1.10.3470.10 9 334 4.4E-61 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS06275 3c2f8c7f5a19c01bb3ba8c3196313dbd 334 SUPERFAMILY SSF81345 12 329 2.62E-78 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWR44_RS06275 3c2f8c7f5a19c01bb3ba8c3196313dbd 334 Pfam PF01032 FecCD transport family 22 329 1.0E-88 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR44_RS02920 01b03a516191fae9140d58786c30036b 314 Gene3D G3DSA:3.40.190.100 141 257 1.6E-25 T 28-03-2018 CWR44_RS02920 01b03a516191fae9140d58786c30036b 314 SUPERFAMILY SSF53850 43 310 7.24E-54 T 28-03-2018 CWR44_RS02920 01b03a516191fae9140d58786c30036b 314 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 45 298 8.5E-48 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CWR44_RS02920 01b03a516191fae9140d58786c30036b 314 Gene3D G3DSA:3.40.190.10 44 140 1.1E-6 T 28-03-2018 CWR44_RS02655 336560495daddfd361b2d80e4bd47e47 663 PIRSF PIRSF018968 1 662 3.2E-52 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWR44_RS07785 d4c2fa241996aeb4fcf0815b51bcf0c7 201 Pfam PF00510 Cytochrome c oxidase subunit III 19 196 1.1E-12 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07785 d4c2fa241996aeb4fcf0815b51bcf0c7 201 SUPERFAMILY SSF81452 13 196 4.06E-50 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07785 d4c2fa241996aeb4fcf0815b51bcf0c7 201 Gene3D G3DSA:1.20.120.80 12 198 4.3E-47 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS07785 d4c2fa241996aeb4fcf0815b51bcf0c7 201 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 9 198 3.5E-103 T 28-03-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 CWR44_RS03240 4aec4bcb3ba0efcb7d2e8e34a0292ae7 223 Gene3D G3DSA:3.20.20.70 2 223 4.8E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS03240 4aec4bcb3ba0efcb7d2e8e34a0292ae7 223 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 24 222 8.0E-68 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CWR44_RS03240 4aec4bcb3ba0efcb7d2e8e34a0292ae7 223 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 1 221 40.323 T 28-03-2018 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9 CWR44_RS03240 4aec4bcb3ba0efcb7d2e8e34a0292ae7 223 SUPERFAMILY SSF51366 2 220 6.88E-62 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CWR44_RS11885 6ef9ccfbdee8a91221d2945df0ba8f31 464 Gene3D G3DSA:3.50.50.60 1 72 1.4E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11885 6ef9ccfbdee8a91221d2945df0ba8f31 464 SUPERFAMILY SSF51905 3 319 1.38E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11885 6ef9ccfbdee8a91221d2945df0ba8f31 464 SUPERFAMILY SSF51905 429 461 1.38E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS11885 6ef9ccfbdee8a91221d2945df0ba8f31 464 Pfam PF01593 Flavin containing amine oxidoreductase 12 461 1.9E-56 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CWR44_RS11885 6ef9ccfbdee8a91221d2945df0ba8f31 464 Gene3D G3DSA:1.10.3110.10 107 204 1.2E-28 T 28-03-2018 CWR44_RS11885 6ef9ccfbdee8a91221d2945df0ba8f31 464 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 3 461 6.2E-115 T 28-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CWR44_RS11885 6ef9ccfbdee8a91221d2945df0ba8f31 464 Gene3D G3DSA:3.90.660.20 216 411 9.5E-38 T 28-03-2018 CWR44_RS11885 6ef9ccfbdee8a91221d2945df0ba8f31 464 SUPERFAMILY SSF54373 304 411 5.69E-28 T 28-03-2018 CWR44_RS07450 3eab748a783dc843ec38b3903b4ba28b 64 Pfam PF11151 Protein of unknown function (DUF2929) 1 56 8.2E-21 T 28-03-2018 IPR021324 Protein of unknown function DUF2929 CWR44_RS12635 ebed182860139415a2fde488ede243ff 261 Pfam PF00795 Carbon-nitrogen hydrolase 14 243 2.6E-46 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR44_RS12635 ebed182860139415a2fde488ede243ff 261 Gene3D G3DSA:3.60.110.10 1 261 1.8E-71 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR44_RS12635 ebed182860139415a2fde488ede243ff 261 SUPERFAMILY SSF56317 1 253 2.62E-66 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CWR44_RS02590 e5e61de5574aaa6d644dae0318591a3f 456 TIGRFAM TIGR00784 citMHS: citrate transporter 8 456 1.6E-89 T 28-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 CWR44_RS02590 e5e61de5574aaa6d644dae0318591a3f 456 Pfam PF03600 Citrate transporter 32 401 2.9E-45 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CWR44_RS11495 205213a554220150c068286cebdfd96d 487 Pfam PF00367 phosphotransferase system, EIIB 416 448 3.8E-15 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS11495 205213a554220150c068286cebdfd96d 487 Gene3D G3DSA:3.30.1360.60 411 487 9.7E-28 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS11495 205213a554220150c068286cebdfd96d 487 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 426 443 - T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CWR44_RS11495 205213a554220150c068286cebdfd96d 487 SUPERFAMILY SSF55604 413 486 7.19E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS11495 205213a554220150c068286cebdfd96d 487 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 484 1.1E-200 T 28-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 CWR44_RS11495 205213a554220150c068286cebdfd96d 487 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 377 473 1.4E-14 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CWR44_RS11495 205213a554220150c068286cebdfd96d 487 Pfam PF02378 Phosphotransferase system, EIIC 10 316 1.6E-74 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS10700 7c9dfb3eb92747e3fc37066865fa2c4e 281 Pfam PF00950 ABC 3 transport family 8 270 2.1E-56 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CWR44_RS10700 7c9dfb3eb92747e3fc37066865fa2c4e 281 SUPERFAMILY SSF81345 5 264 6.93E-33 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWR44_RS10700 7c9dfb3eb92747e3fc37066865fa2c4e 281 Gene3D G3DSA:1.10.3470.10 2 276 1.4E-22 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS08435 016216f9751678884198486472685ba7 202 SUPERFAMILY SSF53271 1 199 4.72E-53 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CWR44_RS08435 016216f9751678884198486472685ba7 202 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 9 176 5.4E-44 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08435 016216f9751678884198486472685ba7 202 Pfam PF00156 Phosphoribosyl transferase domain 44 174 1.6E-21 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CWR44_RS08435 016216f9751678884198486472685ba7 202 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 202 28.304 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CWR44_RS08435 016216f9751678884198486472685ba7 202 Gene3D G3DSA:3.40.50.2020 1 202 7.0E-40 T 28-03-2018 CWR44_RS12340 4eaaacbccee5ee1042db44564ad16bf3 239 Gene3D G3DSA:3.40.50.880 13 213 1.1E-16 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS12340 4eaaacbccee5ee1042db44564ad16bf3 239 SUPERFAMILY SSF52317 16 189 3.16E-22 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CWR44_RS12340 4eaaacbccee5ee1042db44564ad16bf3 239 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 6 196 7.6E-42 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CWR44_RS00580 0e32f3f3f4ad36d4606bf239edb6527d 268 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 16 268 2.7E-88 T 28-03-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like CWR44_RS00580 0e32f3f3f4ad36d4606bf239edb6527d 268 Gene3D G3DSA:3.40.50.1820 20 268 7.4E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS00580 0e32f3f3f4ad36d4606bf239edb6527d 268 SUPERFAMILY SSF53474 27 232 1.81E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CWR44_RS07435 d1ce25d98531203b325b0190b658d43f 102 SUPERFAMILY SSF117916 3 100 3.04E-32 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CWR44_RS07435 d1ce25d98531203b325b0190b658d43f 102 Pfam PF01883 Iron-sulfur cluster assembly protein 6 80 3.4E-19 T 28-03-2018 IPR002744 MIP18 family-like CWR44_RS07435 d1ce25d98531203b325b0190b658d43f 102 Gene3D G3DSA:3.30.300.130 2 101 5.9E-27 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CWR44_RS11975 56418c361da6084354f509734186f3e3 274 Pfam PF00849 RNA pseudouridylate synthase 83 229 1.3E-25 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS11975 56418c361da6084354f509734186f3e3 274 Gene3D G3DSA:3.30.2350.10 74 271 1.8E-49 T 28-03-2018 CWR44_RS11975 56418c361da6084354f509734186f3e3 274 SUPERFAMILY SSF55120 67 271 4.96E-51 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CWR44_RS11615 5f7ea96969a3ad260b75388e0a00976c 263 Pfam PF01636 Phosphotransferase enzyme family 22 215 3.8E-18 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CWR44_RS11615 5f7ea96969a3ad260b75388e0a00976c 263 Gene3D G3DSA:3.90.1200.10 29 257 4.1E-20 T 28-03-2018 CWR44_RS11615 5f7ea96969a3ad260b75388e0a00976c 263 SUPERFAMILY SSF56112 2 227 2.04E-25 T 28-03-2018 IPR011009 Protein kinase-like domain CWR44_RS03095 e02cf06d0c108bfad8f0acd517606f35 211 Pfam PF13346 ABC-2 family transporter protein 3 206 1.9E-26 T 28-03-2018 IPR025699 ABC-2 membrane transporter-like CWR44_RS00975 577e6a2f838060ef9b744d466aabb15f 107 Pfam PF14470 Bacterial PH domain 19 103 1.2E-11 T 28-03-2018 CWR44_RS08385 cd53b69f2a9384bd13c74776b58e397b 159 SUPERFAMILY SSF54001 45 135 1.47E-18 T 28-03-2018 CWR44_RS08385 cd53b69f2a9384bd13c74776b58e397b 159 Pfam PF05257 CHAP domain 47 126 1.5E-14 T 28-03-2018 IPR007921 CHAP domain CWR44_RS10270 dc5f43fd2fb3eccf6ebaf1f955328adc 229 Pfam PF04298 Putative neutral zinc metallopeptidase 3 224 3.0E-90 T 28-03-2018 IPR007395 Putative neutral zinc metallopeptidase CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 PIRSF PIRSF000349 1 199 7.5E-82 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 SUPERFAMILY SSF54719 91 197 2.49E-45 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 SUPERFAMILY SSF46609 1 90 2.23E-39 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 1.4E-26 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.4E-26 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.4E-26 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 PRINTS PR01703 Manganese superoxide dismutase signature 123 131 1.4E-26 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 PRINTS PR01703 Manganese superoxide dismutase signature 159 171 1.4E-26 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 161 168 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 88 2.0E-35 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 95 193 1.1E-42 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CWR44_RS10690 e40fa6b244d18e1d8ddd7787c6b79404 199 Gene3D G3DSA:1.10.287.990 20 89 7.8E-32 T 28-03-2018 CWR44_RS03900 050d9d9b6941b42b812d985b82c12334 152 Pfam PF08877 MepB protein 27 147 1.8E-44 T 28-03-2018 IPR011235 MepB-like CWR44_RS03900 050d9d9b6941b42b812d985b82c12334 152 PIRSF PIRSF032285 1 152 7.3E-54 T 28-03-2018 IPR011235 MepB-like CWR44_RS03650 eaaf2ed2b331c5c2ca5073627afd4f71 225 Gene3D G3DSA:3.30.1380.10 64 197 5.8E-38 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWR44_RS03650 eaaf2ed2b331c5c2ca5073627afd4f71 225 SUPERFAMILY SSF55166 75 205 1.73E-34 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CWR44_RS03650 eaaf2ed2b331c5c2ca5073627afd4f71 225 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 75 200 1.1E-43 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CWR44_RS08960 c3b1b7e81e968e61673a854b9b9da2c9 374 Pfam PF14657 Arm DNA-binding domain 10 53 7.2E-9 T 28-03-2018 IPR028259 AP2-like integrase, N-terminal domain CWR44_RS08960 c3b1b7e81e968e61673a854b9b9da2c9 374 Gene3D G3DSA:1.10.443.10 168 364 2.2E-36 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS08960 c3b1b7e81e968e61673a854b9b9da2c9 374 Pfam PF00589 Phage integrase family 168 356 1.1E-28 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS08960 c3b1b7e81e968e61673a854b9b9da2c9 374 SUPERFAMILY SSF56349 60 358 1.94E-60 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR44_RS08960 c3b1b7e81e968e61673a854b9b9da2c9 374 Pfam PF13102 Phage integrase SAM-like domain 61 152 5.1E-9 T 28-03-2018 IPR025269 Phage integrase SAM-like domain CWR44_RS08960 c3b1b7e81e968e61673a854b9b9da2c9 374 Gene3D G3DSA:1.10.150.130 52 163 4.5E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CWR44_RS01155 f6a071efe2f9121bd4dff507335af575 293 SUPERFAMILY SSF51735 51 290 3.28E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS01155 f6a071efe2f9121bd4dff507335af575 293 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 185 213 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CWR44_RS01155 f6a071efe2f9121bd4dff507335af575 293 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 58 290 2.4E-51 T 28-03-2018 CWR44_RS01155 f6a071efe2f9121bd4dff507335af575 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 236 5.7E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01155 f6a071efe2f9121bd4dff507335af575 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 50 67 5.7E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01155 f6a071efe2f9121bd4dff507335af575 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 254 274 5.7E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01155 f6a071efe2f9121bd4dff507335af575 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 217 5.7E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS01155 f6a071efe2f9121bd4dff507335af575 293 Gene3D G3DSA:3.40.50.720 1 293 4.1E-64 T 28-03-2018 CWR44_RS02050 22a78dd52542ee6e04b247013b54882c 265 SUPERFAMILY SSF56784 1 263 2.89E-56 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS02050 22a78dd52542ee6e04b247013b54882c 265 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 259 1.3E-52 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS02050 22a78dd52542ee6e04b247013b54882c 265 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 259 7.0E-47 T 28-03-2018 IPR000150 Cof family GO:0016787 CWR44_RS02050 22a78dd52542ee6e04b247013b54882c 265 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 231 1.4E-22 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CWR44_RS02050 22a78dd52542ee6e04b247013b54882c 265 Gene3D G3DSA:3.40.50.1000 1 265 4.3E-28 T 28-03-2018 IPR023214 HAD-like domain CWR44_RS02050 22a78dd52542ee6e04b247013b54882c 265 ProSitePatterns PS01229 Hypothetical cof family signature 2. 212 234 - T 28-03-2018 CWR44_RS02790 0b246c8d1e1ded7d15d4564435a4fc6c 110 Pfam PF13630 SdpI/YhfL protein family 24 96 2.5E-11 T 28-03-2018 IPR025962 SdpI/YhfL protein family CWR44_RS04490 0d1000e71dcf68fcb6fc054934853cee 179 Gene3D G3DSA:1.10.260.40 45 174 3.4E-5 T 28-03-2018 CWR44_RS04490 0d1000e71dcf68fcb6fc054934853cee 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 57 1.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CWR44_RS04490 0d1000e71dcf68fcb6fc054934853cee 179 SUPERFAMILY SSF46689 9 72 1.99E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS04490 0d1000e71dcf68fcb6fc054934853cee 179 SUPERFAMILY SSF48498 75 175 6.23E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CWR44_RS04490 0d1000e71dcf68fcb6fc054934853cee 179 Gene3D G3DSA:1.10.10.60 3 44 1.7E-8 T 28-03-2018 CWR44_RS09200 54b4c3345bfa71bc83b680cedb6becd6 342 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 141 327 6.9E-16 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWR44_RS09200 54b4c3345bfa71bc83b680cedb6becd6 342 SUPERFAMILY SSF52266 137 335 3.83E-38 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CWR44_RS09200 54b4c3345bfa71bc83b680cedb6becd6 342 Gene3D G3DSA:3.40.50.1110 118 342 5.7E-29 T 28-03-2018 CWR44_RS06500 55503b70ee92eed4e8dff9c896b45edd 205 Pfam PF07099 Protein of unknown function (DUF1361) 30 193 2.7E-35 T 28-03-2018 IPR009793 Protein of unknown function DUF1361 CWR44_RS05150 c6b81686f4dbb3714cf9f1df2e82bf34 373 Gene3D G3DSA:1.10.287.70 1 366 0.0012 T 28-03-2018 CWR44_RS05150 c6b81686f4dbb3714cf9f1df2e82bf34 373 Pfam PF07907 YibE/F-like protein 131 362 4.4E-66 T 28-03-2018 IPR012507 YibE/F-like CWR44_RS04665 cb00f4653c043e66dd89046e2da3e0e6 152 Pfam PF06998 Protein of unknown function (DUF1307) 24 148 5.9E-28 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 CWR44_RS04665 cb00f4653c043e66dd89046e2da3e0e6 152 SUPERFAMILY SSF160704 20 151 3.79E-37 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 CWR44_RS04665 cb00f4653c043e66dd89046e2da3e0e6 152 Gene3D G3DSA:3.30.1830.10 24 150 1.5E-30 T 28-03-2018 CWR44_RS04665 cb00f4653c043e66dd89046e2da3e0e6 152 PIRSF PIRSF006187 1 152 6.7E-32 T 28-03-2018 IPR009736 Protein of unknown function DUF1307 CWR44_RS09465 58ceee94330e74fac10778b2601b241d 77 Gene3D G3DSA:1.10.260.40 4 75 7.9E-8 T 28-03-2018 CWR44_RS09465 58ceee94330e74fac10778b2601b241d 77 SUPERFAMILY SSF47413 14 73 5.07E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CWR44_RS09015 ef973ce02d2663e9fe3d073c89655019 182 Pfam PF07463 NUMOD4 motif 3 61 2.4E-14 T 28-03-2018 IPR010902 NUMOD4 GO:0016788 CWR44_RS09015 ef973ce02d2663e9fe3d073c89655019 182 Pfam PF13392 HNH endonuclease 69 114 5.3E-10 T 28-03-2018 IPR003615 HNH nuclease CWR44_RS09015 ef973ce02d2663e9fe3d073c89655019 182 SUPERFAMILY SSF54060 3 119 9.06E-28 T 28-03-2018 CWR44_RS06520 c1fd27a70e4d4e15184d5c4cdd526973 159 SUPERFAMILY SSF55826 6 156 4.58E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR44_RS06520 c1fd27a70e4d4e15184d5c4cdd526973 159 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 157 3.3E-58 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CWR44_RS06520 c1fd27a70e4d4e15184d5c4cdd526973 159 Gene3D G3DSA:3.90.960.10 1 158 2.6E-36 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR44_RS06520 c1fd27a70e4d4e15184d5c4cdd526973 159 PIRSF PIRSF006181 1 159 4.1E-61 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CWR44_RS06520 c1fd27a70e4d4e15184d5c4cdd526973 159 Pfam PF04073 Aminoacyl-tRNA editing domain 34 146 1.4E-20 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CWR44_RS09790 ce93f20dbce65a75221674eae65e956d 202 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 200 20.814 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWR44_RS09790 ce93f20dbce65a75221674eae65e956d 202 SMART SM01207 8 192 4.9E-80 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWR44_RS09790 ce93f20dbce65a75221674eae65e956d 202 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 1 201 6.0E-59 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWR44_RS09790 ce93f20dbce65a75221674eae65e956d 202 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 191 5.1E-53 T 28-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CWR44_RS00475 035c021ee2c4b1d78947a7367283c6c0 155 Pfam PF17080 Multidrug Resistance efflux pump 13 154 1.2E-54 T 28-03-2018 IPR031396 Multidrug resistance efflux pump SepA CWR44_RS03235 b1b44c0980198a8a6fc0aad8b357e56b 268 Pfam PF01380 SIS domain 115 239 2.1E-18 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR44_RS03235 b1b44c0980198a8a6fc0aad8b357e56b 268 SUPERFAMILY SSF53697 85 245 1.83E-35 T 28-03-2018 CWR44_RS03235 b1b44c0980198a8a6fc0aad8b357e56b 268 Gene3D G3DSA:1.10.10.10 1 66 2.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS03235 b1b44c0980198a8a6fc0aad8b357e56b 268 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 1.3E-13 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CWR44_RS03235 b1b44c0980198a8a6fc0aad8b357e56b 268 SUPERFAMILY SSF46689 1 77 7.53E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CWR44_RS03235 b1b44c0980198a8a6fc0aad8b357e56b 268 Gene3D G3DSA:3.40.50.10490 67 267 1.5E-34 T 28-03-2018 CWR44_RS09605 bee1167a0446cd5702bf08bab6f9930c 269 Gene3D G3DSA:3.20.20.105 11 231 0.02 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CWR44_RS08085 21907dad3ed9683a059640cd6832d745 408 Pfam PF01098 Cell cycle protein 23 388 5.7E-95 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CWR44_RS07575 b824c6fb3a12437f31e6b99ed2dc4d08 361 Pfam PF01594 AI-2E family transporter 31 341 4.9E-62 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CWR44_RS00180 cc72a3996c1f48c7d005162a4b037924 116 Pfam PF03899 ATP synthase I chain 14 101 7.2E-8 T 28-03-2018 IPR005598 ATP synthase protein I CWR44_RS08095 4a294c6d34cd472f744b750382c678fb 304 Hamap MF_01664 Heme A synthase [ctaA]. 3 302 27.983 T 28-03-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 CWR44_RS08095 4a294c6d34cd472f744b750382c678fb 304 Pfam PF02628 Cytochrome oxidase assembly protein 57 286 5.4E-32 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CWR44_RS12620 f1760b0c62edb62dd2df009a1c06cb9e 246 Pfam PF02517 CAAX protease self-immunity 126 218 5.0E-16 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR44_RS12815 300514ef7bfc5e624f2060038a205fdb 108 Gene3D G3DSA:3.30.750.24 1 105 1.0E-14 T 28-03-2018 IPR002645 STAS domain CWR44_RS12815 300514ef7bfc5e624f2060038a205fdb 108 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 106 1.2E-31 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CWR44_RS12815 300514ef7bfc5e624f2060038a205fdb 108 Pfam PF01740 STAS domain 6 99 7.0E-12 T 28-03-2018 IPR002645 STAS domain CWR44_RS12815 300514ef7bfc5e624f2060038a205fdb 108 SUPERFAMILY SSF52091 3 103 8.63E-24 T 28-03-2018 IPR002645 STAS domain CWR44_RS07545 35b0f72991fc6e4c525841975f36c0a7 209 Gene3D G3DSA:3.30.460.10 1 145 2.3E-36 T 28-03-2018 CWR44_RS07545 35b0f72991fc6e4c525841975f36c0a7 209 Gene3D G3DSA:1.10.287.860 147 195 1.6E-20 T 28-03-2018 CWR44_RS07545 35b0f72991fc6e4c525841975f36c0a7 209 Pfam PF04607 Region found in RelA / SpoT proteins 43 162 3.9E-37 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR44_RS07545 35b0f72991fc6e4c525841975f36c0a7 209 SMART SM00954 43 164 1.1E-41 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CWR44_RS07545 35b0f72991fc6e4c525841975f36c0a7 209 SUPERFAMILY SSF81301 3 199 3.43E-60 T 28-03-2018 CWR44_RS00495 974dbc0c4eb9b32602489da426f974e5 172 PIRSF PIRSF030780 9 171 2.7E-20 T 28-03-2018 IPR016956 Inner membrane protein YdjM CWR44_RS00495 974dbc0c4eb9b32602489da426f974e5 172 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 155 2.0E-30 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CWR44_RS00835 113ea83d590a95bce952d69605a504d9 302 Pfam PF03547 Membrane transport protein 1 140 6.8E-8 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CWR44_RS10135 4918371426f58a55e9c987ba9de2f97f 144 Pfam PF06491 Disulphide isomerase 7 144 4.2E-55 T 28-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CWR44_RS10135 4918371426f58a55e9c987ba9de2f97f 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 7 144 2.4E-57 T 28-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CWR44_RS01450 b33a570f849c6f46056dda5364e0a603 117 Pfam PF16230 Domain of unknown function (DUF4889) 41 111 3.6E-30 T 28-03-2018 IPR032613 Protein of unknown function DUF4889 CWR44_RS04510 477a0740417020d44c6c0ff200997dd4 627 Pfam PF02687 FtsX-like permease family 85 174 4.3E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR44_RS04510 477a0740417020d44c6c0ff200997dd4 627 PIRSF PIRSF018968 1 627 4.2E-101 T 28-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CWR44_RS10620 f6a52fa189736c155e2a03797b8d458d 142 Pfam PF15980 Putative Competence protein ComGF 46 122 1.0E-6 T 28-03-2018 IPR016977 Competence operon G, ComGF CWR44_RS08625 0ca13bb07b8d4cf66455b4f04a63b516 864 Pfam PF09586 Bacterial membrane protein YfhO 13 841 1.6E-144 T 28-03-2018 IPR018580 Uncharacterised protein family YfhO CWR44_RS01930 eff7b30dc1147ba509261c6539e90f1e 645 Pfam PF13515 Fusaric acid resistance protein-like 347 472 3.5E-19 T 28-03-2018 CWR44_RS00810 d10203a31955336ce10ec6e70a71061f 444 Pfam PF00860 Permease family 16 404 1.1E-44 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CWR44_RS00810 d10203a31955336ce10ec6e70a71061f 444 PIRSF PIRSF005353 1 444 2.5E-171 T 28-03-2018 IPR026033 Purine permease PbuG-like CWR44_RS08245 7bbe5616db66741b2a9fd5995a280112 169 SUPERFAMILY SSF56300 1 164 1.78E-38 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS08245 7bbe5616db66741b2a9fd5995a280112 169 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 144 3.3E-23 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CWR44_RS08245 7bbe5616db66741b2a9fd5995a280112 169 Gene3D G3DSA:3.60.21.10 1 164 8.7E-17 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS08245 7bbe5616db66741b2a9fd5995a280112 169 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 145 2.6E-22 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CWR44_RS10510 6cb0a45e5fa35548738eb2d1462fb112 333 SUPERFAMILY SSF52518 3 325 1.02E-91 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CWR44_RS10510 6cb0a45e5fa35548738eb2d1462fb112 333 Gene3D G3DSA:3.40.50.970 1 329 2.5E-76 T 28-03-2018 CWR44_RS10510 6cb0a45e5fa35548738eb2d1462fb112 333 Pfam PF00676 Dehydrogenase E1 component 19 316 4.4E-84 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CWR44_RS05370 12436dd7285c76b7f5af4c188d05473d 133 SMART SM00316 4 74 2.6E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 CWR44_RS05370 12436dd7285c76b7f5af4c188d05473d 133 Pfam PF00575 S1 RNA binding domain 4 74 4.7E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 CWR44_RS05370 12436dd7285c76b7f5af4c188d05473d 133 Gene3D G3DSA:2.40.50.140 7 106 1.3E-28 T 28-03-2018 CWR44_RS05370 12436dd7285c76b7f5af4c188d05473d 133 SUPERFAMILY SSF50249 4 85 5.02E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CWR44_RS01365 c70f9bdb740f047155bbaedd21ee28b1 408 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 63 397 6.5E-91 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CWR44_RS01365 c70f9bdb740f047155bbaedd21ee28b1 408 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 6 408 2.1E-163 T 28-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 CWR44_RS01365 c70f9bdb740f047155bbaedd21ee28b1 408 Pfam PF04261 Dyp-type peroxidase family 63 397 7.5E-108 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CWR44_RS01365 c70f9bdb740f047155bbaedd21ee28b1 408 SUPERFAMILY SSF54909 58 401 5.9E-80 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CWR44_RS01365 c70f9bdb740f047155bbaedd21ee28b1 408 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 12 32 1.2E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CWR44_RS00285 3fe2596116735957afed2469399062e1 221 Pfam PF11042 Protein of unknown function (DUF2750) 116 219 3.8E-23 T 28-03-2018 IPR021284 Protein of unknown function DUF2750 CWR44_RS00285 3fe2596116735957afed2469399062e1 221 Pfam PF11042 Protein of unknown function (DUF2750) 15 106 9.4E-7 T 28-03-2018 IPR021284 Protein of unknown function DUF2750 CWR44_RS03405 41570da250686ab4ddfe7b98d54a0849 302 Gene3D G3DSA:3.40.50.150 74 292 8.9E-6 T 28-03-2018 CWR44_RS06345 445c6eed8e374ffc5a070411365b8eda 205 Gene3D G3DSA:1.20.58.220 78 204 1.8E-5 T 28-03-2018 CWR44_RS06345 445c6eed8e374ffc5a070411365b8eda 205 Pfam PF01865 Protein of unknown function DUF47 5 202 3.3E-20 T 28-03-2018 IPR018445 Putative phosphate transport regulator CWR44_RS13140 c15af7cbcc3b9e909248bb3488ec5365 240 SUPERFAMILY SSF46785 85 181 2.99E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS13140 c15af7cbcc3b9e909248bb3488ec5365 240 Gene3D G3DSA:1.10.10.10 96 187 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS13140 c15af7cbcc3b9e909248bb3488ec5365 240 Gene3D G3DSA:1.10.10.10 3 95 1.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS13140 c15af7cbcc3b9e909248bb3488ec5365 240 Pfam PF01051 Initiator Replication protein 10 178 1.3E-32 T 28-03-2018 IPR000525 Initiator Rep protein GO:0003887|GO:0005727|GO:0006270 CWR44_RS07115 053ee06613dc4b87e382ae1910ec5e7f 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 53 231 2.0E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS07115 053ee06613dc4b87e382ae1910ec5e7f 231 SUPERFAMILY SSF161098 20 221 1.7E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CWR44_RS07115 053ee06613dc4b87e382ae1910ec5e7f 231 Gene3D G3DSA:1.10.3720.10 16 231 1.3E-44 T 28-03-2018 CWR44_RS06320 ecaa6aca70c9ac58c2e04064ecf01803 307 Gene3D G3DSA:3.40.50.720 2 154 5.1E-11 T 28-03-2018 CWR44_RS06320 ecaa6aca70c9ac58c2e04064ecf01803 307 Pfam PF13460 NAD(P)H-binding 9 126 1.7E-7 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS06320 ecaa6aca70c9ac58c2e04064ecf01803 307 SUPERFAMILY SSF51735 2 119 3.96E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS11935 be4c87e769b948d7e68e0ba7a794aa6d 313 Pfam PF01336 OB-fold nucleic acid binding domain 27 87 1.2E-6 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CWR44_RS11935 be4c87e769b948d7e68e0ba7a794aa6d 313 Gene3D G3DSA:2.40.50.140 5 99 1.2E-8 T 28-03-2018 CWR44_RS11935 be4c87e769b948d7e68e0ba7a794aa6d 313 SUPERFAMILY SSF109604 141 279 3.45E-15 T 28-03-2018 CWR44_RS11935 be4c87e769b948d7e68e0ba7a794aa6d 313 Gene3D G3DSA:1.10.3210.10 121 309 2.8E-15 T 28-03-2018 CWR44_RS11935 be4c87e769b948d7e68e0ba7a794aa6d 313 Pfam PF01966 HD domain 161 277 2.5E-10 T 28-03-2018 IPR006674 HD domain CWR44_RS11935 be4c87e769b948d7e68e0ba7a794aa6d 313 SMART SM00471 155 287 0.0039 T 28-03-2018 IPR003607 HD/PDEase domain CWR44_RS04230 6ed25cb9f19932715d04154b5710d2e8 112 Pfam PF06106 S. aureus uracil DNA glycosylase inhibitor 2 111 7.4E-42 T 28-03-2018 IPR009295 Uracil DNA glycosylase inhibitor CWR44_RS03580 5e6bcb352fa783b48bdc0a7d369dde73 464 Pfam PF03606 C4-dicarboxylate anaerobic carrier 14 459 1.1E-103 T 28-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CWR44_RS01280 a8f8cbf6a74b05932961cd4cf46676c1 454 PIRSF PIRSF032522 1 454 1.1E-157 T 28-03-2018 IPR023599 Membrane-associated protein TcaA GO:0016021|GO:0046677 CWR44_RS01280 a8f8cbf6a74b05932961cd4cf46676c1 454 Gene3D G3DSA:2.20.28.20 1 35 9.6E-5 T 28-03-2018 CWR44_RS12280 45ca67fce08ff02c48f1bb730287c98c 69 Hamap MF_00829 UPF0435 protein . 1 68 20.74 T 28-03-2018 IPR009507 Protein of unknown function UPF0435 CWR44_RS12280 45ca67fce08ff02c48f1bb730287c98c 69 Pfam PF06569 Protein of unknown function (DUF1128) 2 68 2.2E-28 T 28-03-2018 IPR009507 Protein of unknown function UPF0435 CWR44_RS08040 94108c35cde123f7c5d87f01252df1f7 161 Pfam PF13273 Protein of unknown function (DUF4064) 2 104 5.0E-19 T 28-03-2018 IPR025273 Domain of unknown function DUF4064 CWR44_RS02295 d5b332cc20afd38302c88d6261cf788f 502 Gene3D G3DSA:3.50.50.60 2 347 5.4E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS02295 d5b332cc20afd38302c88d6261cf788f 502 SUPERFAMILY SSF51905 452 491 1.62E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS02295 d5b332cc20afd38302c88d6261cf788f 502 SUPERFAMILY SSF51905 1 320 1.62E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CWR44_RS02295 d5b332cc20afd38302c88d6261cf788f 502 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 7 491 2.4E-100 T 28-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 CWR44_RS02295 d5b332cc20afd38302c88d6261cf788f 502 Pfam PF01593 Flavin containing amine oxidoreductase 13 489 1.6E-24 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CWR44_RS10420 70e7144e782f406016b89e7ed7287241 148 Pfam PF01475 Ferric uptake regulator family 15 136 8.7E-40 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CWR44_RS10420 70e7144e782f406016b89e7ed7287241 148 SUPERFAMILY SSF46785 7 141 6.61E-39 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS10420 70e7144e782f406016b89e7ed7287241 148 Gene3D G3DSA:1.10.10.10 1 87 1.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01545 bad0bb7b11a288f8cbe6318021e99626 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 18 155 1.3E-18 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CWR44_RS01545 bad0bb7b11a288f8cbe6318021e99626 159 Gene3D G3DSA:3.30.530.20 1 159 8.7E-17 T 28-03-2018 IPR023393 START-like domain CWR44_RS01545 bad0bb7b11a288f8cbe6318021e99626 159 SUPERFAMILY SSF55961 7 157 3.57E-31 T 28-03-2018 CWR44_RS07770 f3c8d19668be7f4425b077dbde07a4d6 391 Pfam PF00144 Beta-lactamase 86 365 3.4E-45 T 28-03-2018 IPR001466 Beta-lactamase-related CWR44_RS07770 f3c8d19668be7f4425b077dbde07a4d6 391 SUPERFAMILY SSF56601 71 379 8.72E-62 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CWR44_RS07770 f3c8d19668be7f4425b077dbde07a4d6 391 Gene3D G3DSA:3.40.710.10 71 382 1.1E-51 T 28-03-2018 CWR44_RS07125 84c6a9bce33dbc04e85acb3b0f569845 64 Pfam PF05532 CsbD-like 2 52 4.2E-15 T 28-03-2018 IPR008462 CsbD-like domain CWR44_RS07125 84c6a9bce33dbc04e85acb3b0f569845 64 Gene3D G3DSA:1.10.1470.10 1 64 1.4E-16 T 28-03-2018 IPR008462 CsbD-like domain CWR44_RS07125 84c6a9bce33dbc04e85acb3b0f569845 64 SUPERFAMILY SSF69047 3 61 2.22E-10 T 28-03-2018 IPR008462 CsbD-like domain CWR44_RS10000 53611062da36616be20f2cba19740d78 438 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 48 92 1.9E-9 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS10000 53611062da36616be20f2cba19740d78 438 Pfam PF01610 Transposase 164 417 4.0E-52 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS06620 d1429ececcee079320d3c4117eb8a617 272 Pfam PF02535 ZIP Zinc transporter 124 267 1.6E-12 T 28-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CWR44_RS12565 e8f066e28b1cafd6a4f922070dcc238d 133 Pfam PF07070 SpoOM protein 2 130 8.2E-20 T 28-03-2018 IPR009776 Sporulation stage 0, protein M CWR44_RS05520 fd04233635ccfeba6b34c18b65d14d4c 404 Pfam PF07670 Nucleoside recognition 93 190 2.1E-6 T 28-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CWR44_RS05520 fd04233635ccfeba6b34c18b65d14d4c 404 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 6.5E-22 T 28-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CWR44_RS05520 fd04233635ccfeba6b34c18b65d14d4c 404 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 194 403 9.5E-61 T 28-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CWR44_RS01695 8856b457826ae445c7701503172586c2 157 Pfam PF07274 Protein of unknown function (DUF1440) 17 150 1.9E-46 T 28-03-2018 IPR009898 Protein of unknown function DUF1440 CWR44_RS06100 592a32739ee8974afb4ddcec47be3272 238 SUPERFAMILY SSF103473 74 230 1.83E-6 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS04200 409c58306fd0c380e258d1ad55575248 413 Pfam PF01076 Plasmid recombination enzyme 1 198 3.6E-76 T 28-03-2018 IPR001668 Plasmid recombination enzyme GO:0003677|GO:0005727|GO:0006310 CWR44_RS12195 a294620d791bea7e6281374aa3502662 364 Pfam PF06081 Aromatic acid exporter family member 1 2 144 2.0E-27 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CWR44_RS00540 154776b5dc4beb7cd1155e1ff17e836d 389 Pfam PF05977 Transmembrane secretion effector 10 381 2.0E-35 T 28-03-2018 IPR010290 Transmembrane secretion effector CWR44_RS00540 154776b5dc4beb7cd1155e1ff17e836d 389 Gene3D G3DSA:1.20.1250.20 3 194 1.2E-14 T 28-03-2018 CWR44_RS00540 154776b5dc4beb7cd1155e1ff17e836d 389 Gene3D G3DSA:1.20.1250.20 198 388 3.5E-12 T 28-03-2018 CWR44_RS00540 154776b5dc4beb7cd1155e1ff17e836d 389 SUPERFAMILY SSF103473 4 386 2.62E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS07300 67936dc60f580b8a8ecc339b74b89c33 96 PIRSF PIRSF028784 1 92 4.7E-31 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CWR44_RS07300 67936dc60f580b8a8ecc339b74b89c33 96 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 5.5E-14 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CWR44_RS03165 75c89e09f7cba95803de42169eacb051 308 Pfam PF06166 Protein of unknown function (DUF979) 11 308 7.7E-113 T 28-03-2018 IPR009323 Protein of unknown function DUF979 CWR44_RS12855 b17e904f83cf0ee94cd712173acb2bfa 159 Pfam PF03703 Bacterial PH domain 75 145 4.3E-7 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CWR44_RS10530 588f173d3fbd1d00bd81eba86c5b39ff 293 Gene3D G3DSA:1.10.600.10 2 293 1.4E-76 T 28-03-2018 IPR008949 Isoprenoid synthase domain CWR44_RS10530 588f173d3fbd1d00bd81eba86c5b39ff 293 SUPERFAMILY SSF48576 4 285 5.35E-83 T 28-03-2018 IPR008949 Isoprenoid synthase domain CWR44_RS10530 588f173d3fbd1d00bd81eba86c5b39ff 293 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CWR44_RS10530 588f173d3fbd1d00bd81eba86c5b39ff 293 Pfam PF00348 Polyprenyl synthetase 29 252 2.8E-57 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CWR44_RS10530 588f173d3fbd1d00bd81eba86c5b39ff 293 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 79 95 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CWR44_RS12895 af6c1876d1dad44a10d61ca542ec7911 97 Pfam PF02583 Metal-sensitive transcriptional repressor 15 92 6.2E-28 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CWR44_RS00065 af6c1876d1dad44a10d61ca542ec7911 97 Pfam PF02583 Metal-sensitive transcriptional repressor 15 92 6.2E-28 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CWR44_RS10440 56da4fe8961776fa35ac9aecde5ab6d3 251 Gene3D G3DSA:3.40.50.720 1 251 4.2E-43 T 28-03-2018 CWR44_RS10440 56da4fe8961776fa35ac9aecde5ab6d3 251 Pfam PF00106 short chain dehydrogenase 4 185 2.0E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS10440 56da4fe8961776fa35ac9aecde5ab6d3 251 SUPERFAMILY SSF51735 3 245 5.99E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CWR44_RS10440 56da4fe8961776fa35ac9aecde5ab6d3 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 179 7.2E-4 T 28-03-2018 CWR44_RS10440 56da4fe8961776fa35ac9aecde5ab6d3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 3.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS10440 56da4fe8961776fa35ac9aecde5ab6d3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 3.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS10440 56da4fe8961776fa35ac9aecde5ab6d3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 3.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS10440 56da4fe8961776fa35ac9aecde5ab6d3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS10440 56da4fe8961776fa35ac9aecde5ab6d3 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 3.5E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CWR44_RS02420 45c98f004929b1f18fc9d19d41a1e7b7 483 PIRSF PIRSF006060 5 480 4.5E-87 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS02420 45c98f004929b1f18fc9d19d41a1e7b7 483 Pfam PF13520 Amino acid permease 32 456 5.5E-55 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS10155 6fd5cd87b990e88e34642c377b63b166 234 Pfam PF02592 Putative vitamin uptake transporter 57 217 8.7E-44 T 28-03-2018 IPR003744 Queuosine precursor transporter CWR44_RS10155 6fd5cd87b990e88e34642c377b63b166 234 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 26 224 8.2E-58 T 28-03-2018 IPR003744 Queuosine precursor transporter CWR44_RS12850 76a275d815a1140c076b21567f85513b 507 PIRSF PIRSF026631 1 504 4.2E-99 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 CWR44_RS12850 76a275d815a1140c076b21567f85513b 507 Pfam PF03703 Bacterial PH domain 69 143 4.4E-14 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CWR44_RS12850 76a275d815a1140c076b21567f85513b 507 Pfam PF03703 Bacterial PH domain 266 352 3.0E-7 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CWR44_RS04090 c8560e4966aa5cf419e076686b12fca3 26 Pfam PF13333 Integrase core domain 1 23 1.2E-4 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CWR44_RS01015 cf2fb56aa12e181f7ea3de5cd65c0c5a 215 Pfam PF05257 CHAP domain 110 188 3.3E-16 T 28-03-2018 IPR007921 CHAP domain CWR44_RS01015 cf2fb56aa12e181f7ea3de5cd65c0c5a 215 SUPERFAMILY SSF54001 94 212 1.37E-23 T 28-03-2018 CWR44_RS00515 c15a5060f5c1dab5b6fbc66228a3031f 321 Pfam PF01032 FecCD transport family 17 320 1.9E-88 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CWR44_RS00515 c15a5060f5c1dab5b6fbc66228a3031f 321 SUPERFAMILY SSF81345 4 320 9.15E-78 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CWR44_RS00515 c15a5060f5c1dab5b6fbc66228a3031f 321 Gene3D G3DSA:1.10.3470.10 1 321 1.5E-64 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS01425 aeb2883a6f62e945793fbf950c1bf0d6 313 Gene3D G3DSA:3.30.460.20 3 122 1.1E-17 T 28-03-2018 CWR44_RS01425 aeb2883a6f62e945793fbf950c1bf0d6 313 Pfam PF01544 CorA-like Mg2+ transporter protein 21 309 7.2E-57 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CWR44_RS01425 aeb2883a6f62e945793fbf950c1bf0d6 313 Gene3D G3DSA:1.20.58.340 128 245 5.8E-10 T 28-03-2018 CWR44_RS01425 aeb2883a6f62e945793fbf950c1bf0d6 313 Gene3D G3DSA:1.20.58.340 246 313 6.5E-13 T 28-03-2018 CWR44_RS01425 aeb2883a6f62e945793fbf950c1bf0d6 313 SUPERFAMILY SSF144083 248 310 4.32E-13 T 28-03-2018 CWR44_RS01425 aeb2883a6f62e945793fbf950c1bf0d6 313 SUPERFAMILY SSF143865 4 247 5.62E-41 T 28-03-2018 CWR44_RS09750 aae88bb46596a6c94d353ce533f6a7ca 156 Pfam PF07301 Protein of unknown function (DUF1453) 6 150 1.1E-56 T 28-03-2018 IPR009916 Protein of unknown function DUF1453 CWR44_RS09750 aae88bb46596a6c94d353ce533f6a7ca 156 PIRSF PIRSF021441 1 156 1.2E-66 T 28-03-2018 IPR031306 CcdC protein CWR44_RS09005 42cc38a4f092cdc60bcb0174e3ca0d32 224 Pfam PF04404 ERF superfamily 12 168 2.6E-20 T 28-03-2018 IPR007499 Essential recombination function protein CWR44_RS01765 0aced7ffaa31ba61fabd9d77ebd58e6e 554 PIRSF PIRSF006060 1 542 1.9E-61 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS01765 0aced7ffaa31ba61fabd9d77ebd58e6e 554 Pfam PF13520 Amino acid permease 10 430 8.2E-41 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS08060 dd3b5b0d8b568d7aaeb95e2bd156c336 63 Pfam PF17259 Family of unknown function (DUF5325) 5 63 2.0E-17 T 28-03-2018 IPR035211 Protein of unknown function DUF5325 CWR44_RS09815 45d478e27554954dfb1379373a4fdaaf 409 PRINTS PR01988 Putative bacilysin exporter bacE signature 162 179 1.3E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CWR44_RS09815 45d478e27554954dfb1379373a4fdaaf 409 PRINTS PR01988 Putative bacilysin exporter bacE signature 250 267 1.3E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CWR44_RS09815 45d478e27554954dfb1379373a4fdaaf 409 PRINTS PR01988 Putative bacilysin exporter bacE signature 46 64 1.3E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CWR44_RS09815 45d478e27554954dfb1379373a4fdaaf 409 PRINTS PR01988 Putative bacilysin exporter bacE signature 355 378 1.3E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CWR44_RS09815 45d478e27554954dfb1379373a4fdaaf 409 Pfam PF01594 AI-2E family transporter 53 375 3.5E-75 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CWR44_RS01490 65838feeb275d6c2d5b0bea1e4b4b0e5 149 SUPERFAMILY SSF55781 17 132 1.94E-10 T 28-03-2018 IPR029016 GAF domain-like CWR44_RS01490 65838feeb275d6c2d5b0bea1e4b4b0e5 149 Gene3D G3DSA:3.30.450.40 10 143 4.7E-11 T 28-03-2018 IPR029016 GAF domain-like CWR44_RS01490 65838feeb275d6c2d5b0bea1e4b4b0e5 149 Pfam PF13185 GAF domain 24 126 3.0E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 CWR44_RS07240 82bfa5d264d424cabce544b7648c825e 396 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 6 378 3.7E-103 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CWR44_RS07240 82bfa5d264d424cabce544b7648c825e 396 PIRSF PIRSF021438 1 381 2.5E-88 T 28-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CWR44_RS07240 82bfa5d264d424cabce544b7648c825e 396 Gene3D G3DSA:3.40.50.1110 32 394 2.0E-4 T 28-03-2018 CWR44_RS07240 82bfa5d264d424cabce544b7648c825e 396 Pfam PF04914 DltD protein 42 379 5.3E-94 T 28-03-2018 IPR006998 DltD CWR44_RS07800 9474fb0fb684bf234278275466656d8c 105 Gene3D G3DSA:2.60.40.10 28 105 2.5E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWR44_RS07800 9474fb0fb684bf234278275466656d8c 105 Pfam PF16403 Domain of unknown function (DUF5011) 33 104 5.1E-23 T 28-03-2018 IPR032179 Domain of unknown function DUF5011 CWR44_RS09185 dc6428e95cc3082a9fd86fb70de2de21 386 Pfam PF06605 Prophage endopeptidase tail 37 344 3.6E-52 T 28-03-2018 IPR010572 Prophage tail endopeptidase CWR44_RS00595 69d1e8ab284840374622140d2235b1f1 104 Gene3D G3DSA:1.20.58.80 4 102 2.4E-36 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR44_RS00595 69d1e8ab284840374622140d2235b1f1 104 SUPERFAMILY SSF46973 1 102 2.22E-33 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR44_RS00595 69d1e8ab284840374622140d2235b1f1 104 PIRSF PIRSF000699 1 104 3.1E-38 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR44_RS00595 69d1e8ab284840374622140d2235b1f1 104 TIGRFAM TIGR00823 EIIA-LAC: PTS system, lactose-specific IIa component 4 102 1.2E-45 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR44_RS00595 69d1e8ab284840374622140d2235b1f1 104 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 10 101 9.6E-34 T 28-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CWR44_RS09115 3c735f579b2d67059fb281f2c0ab4779 102 Pfam PF05119 Phage terminase, small subunit 15 96 1.3E-10 T 28-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CWR44_RS02225 0e3f15eadd527b5e5dcc3aa7d73475ad 156 Gene3D G3DSA:3.40.1440.10 30 156 1.8E-7 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CWR44_RS04520 f8a97bed9cde9ff7b38f1bd287190052 135 SUPERFAMILY SSF159121 43 135 3.92E-22 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CWR44_RS04520 f8a97bed9cde9ff7b38f1bd287190052 135 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 53 135 1.1E-11 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CWR44_RS04520 f8a97bed9cde9ff7b38f1bd287190052 135 Pfam PF06486 Protein of unknown function (DUF1093) 52 124 4.7E-15 T 28-03-2018 IPR006542 Protein of unknown function DUF1093 CWR44_RS03450 c5e12b0d7fd2a501f911fe668ce6d438 257 SUPERFAMILY SSF103473 76 246 1.11E-6 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS03450 c5e12b0d7fd2a501f911fe668ce6d438 257 SUPERFAMILY SSF158560 2 75 9.16E-8 T 28-03-2018 CWR44_RS03450 c5e12b0d7fd2a501f911fe668ce6d438 257 Gene3D G3DSA:1.10.1900.10 1 72 7.4E-8 T 28-03-2018 CWR44_RS01315 89b77d332bccc4d2bfef54a91e9467c6 146 SMART SM00850 49 145 2.5E-23 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR44_RS01315 89b77d332bccc4d2bfef54a91e9467c6 146 Gene3D G3DSA:2.40.50.40 39 108 3.2E-10 T 28-03-2018 CWR44_RS01315 89b77d332bccc4d2bfef54a91e9467c6 146 Pfam PF04397 LytTr DNA-binding domain 51 144 1.5E-20 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CWR44_RS02020 6dc12cdf575642d27e084ed8eb7f576a 93 Gene3D G3DSA:3.40.630.30 2 92 1.2E-19 T 28-03-2018 CWR44_RS02020 6dc12cdf575642d27e084ed8eb7f576a 93 Pfam PF14542 GCN5-related N-acetyl-transferase 12 90 8.4E-26 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CWR44_RS02020 6dc12cdf575642d27e084ed8eb7f576a 93 SUPERFAMILY SSF55729 4 91 1.05E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS01925 4f31a27ecc931136e6a837c7e0f0c3e3 139 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 87 136 1.6E-10 T 28-03-2018 IPR018691 Protein of unknown function DUF2188 CWR44_RS06380 26aae665a53dd640e92cef81a95a6ac8 162 SUPERFAMILY SSF51182 2 156 6.48E-60 T 28-03-2018 IPR011051 RmlC-like cupin domain CWR44_RS06380 26aae665a53dd640e92cef81a95a6ac8 162 Gene3D G3DSA:2.60.120.10 1 157 2.5E-58 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CWR44_RS06380 26aae665a53dd640e92cef81a95a6ac8 162 Pfam PF06172 Cupin superfamily (DUF985) 7 135 5.0E-44 T 28-03-2018 IPR009327 Cupin domain of unknown function DUF985 CWR44_RS09915 04c225ccdcc484c5abd2d2a960e3d7f7 113 Gene3D G3DSA:1.20.1250.20 31 107 8.3E-4 T 28-03-2018 CWR44_RS01100 2585bce6148b5ef3b62797371445bb3b 462 Pfam PF00324 Amino acid permease 16 430 6.4E-100 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CWR44_RS01100 2585bce6148b5ef3b62797371445bb3b 462 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CWR44_RS01100 2585bce6148b5ef3b62797371445bb3b 462 PIRSF PIRSF006060 1 460 2.0E-71 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS04765 5340be8bac2923c4719fa989ece28adb 376 SUPERFAMILY SSF51395 3 343 5.92E-85 T 28-03-2018 CWR44_RS04765 5340be8bac2923c4719fa989ece28adb 376 Gene3D G3DSA:3.20.20.70 1 354 1.0E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CWR44_RS04765 5340be8bac2923c4719fa989ece28adb 376 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 339 6.6E-71 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CWR44_RS04760 d72c76117f1552bfc0dbe4eaa291289a 140 SUPERFAMILY SSF46785 6 127 6.67E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS04760 d72c76117f1552bfc0dbe4eaa291289a 140 Gene3D G3DSA:1.10.10.10 21 123 4.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS12530 bd6dc70b0840d894cfb8ce74a950710e 290 Gene3D G3DSA:3.40.50.300 1 279 1.8E-48 T 28-03-2018 CWR44_RS12530 bd6dc70b0840d894cfb8ce74a950710e 290 SUPERFAMILY SSF52540 2 206 1.81E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CWR44_RS12530 bd6dc70b0840d894cfb8ce74a950710e 290 SMART SM00382 25 196 2.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CWR44_RS12530 bd6dc70b0840d894cfb8ce74a950710e 290 Pfam PF00005 ABC transporter 16 148 2.9E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CWR44_RS07695 e474ea74e32f8984092824a11f42a5d6 184 Gene3D G3DSA:3.40.630.30 1 183 1.2E-31 T 28-03-2018 CWR44_RS07695 e474ea74e32f8984092824a11f42a5d6 184 SUPERFAMILY SSF55729 2 182 2.13E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS07695 e474ea74e32f8984092824a11f42a5d6 184 Pfam PF00583 Acetyltransferase (GNAT) family 50 164 9.6E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS02055 d287e3c755737957ec661e9a7e2a6225 200 TIGRFAM TIGR01076 sortase_fam: sortase 68 199 1.4E-44 T 28-03-2018 IPR005754 Sortase family CWR44_RS02055 d287e3c755737957ec661e9a7e2a6225 200 SUPERFAMILY SSF63817 14 200 3.4E-38 T 28-03-2018 IPR023365 Sortase domain CWR44_RS02055 d287e3c755737957ec661e9a7e2a6225 200 Gene3D G3DSA:2.40.260.10 57 200 3.1E-29 T 28-03-2018 IPR023365 Sortase domain CWR44_RS02055 d287e3c755737957ec661e9a7e2a6225 200 Pfam PF04203 Sortase family 70 198 1.8E-20 T 28-03-2018 IPR005754 Sortase family CWR44_RS06140 af157d3754af39bd6300fdbf7ef6e5e1 185 Gene3D G3DSA:1.10.443.10 7 177 1.9E-26 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS06140 af157d3754af39bd6300fdbf7ef6e5e1 185 SUPERFAMILY SSF56349 4 175 1.32E-32 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CWR44_RS06140 af157d3754af39bd6300fdbf7ef6e5e1 185 Pfam PF00589 Phage integrase family 10 167 7.5E-21 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CWR44_RS00260 4d176b79f5cf367f752db339ff0b90ea 173 Pfam PF10740 Domain of unknown function (DUF2529) 1 168 4.4E-58 T 28-03-2018 IPR019676 Domain of unknown function (DUF2529) CWR44_RS10410 84b0590a02bd85f51853c1bd858a7c28 173 Pfam PF03745 Domain of unknown function (DUF309) 6 62 4.0E-17 T 28-03-2018 IPR005500 Protein of unknown function DUF309 CWR44_RS10410 84b0590a02bd85f51853c1bd858a7c28 173 Gene3D G3DSA:1.10.3450.10 2 129 3.5E-20 T 28-03-2018 IPR023203 TTHA0068-like domain CWR44_RS10410 84b0590a02bd85f51853c1bd858a7c28 173 SUPERFAMILY SSF140663 2 122 7.19E-20 T 28-03-2018 IPR023203 TTHA0068-like domain CWR44_RS02825 04e6dbbbb8c6d3a53528b2ca1952f504 121 Pfam PF09685 Domain of unknown function (DUF4870) 20 120 6.7E-29 T 28-03-2018 IPR019109 Protein of unknown function DUF4870 CWR44_RS12510 55dde31931f92f06fefe6755d2d1d9a2 161 Gene3D G3DSA:1.20.1070.10 5 28 9.1E-4 T 28-03-2018 CWR44_RS03020 aadc096138db372ca07465bd6e4dd975 160 Gene3D G3DSA:3.40.630.30 1 160 3.5E-27 T 28-03-2018 CWR44_RS03020 aadc096138db372ca07465bd6e4dd975 160 Pfam PF13673 Acetyltransferase (GNAT) domain 23 159 2.6E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS03020 aadc096138db372ca07465bd6e4dd975 160 SUPERFAMILY SSF55729 2 159 2.57E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS10640 89629577fdc7e69c54dab2d694a4f03d 354 PRINTS PR00812 Bacterial general secretion pathway protein F signature 116 144 6.3E-7 T 28-03-2018 IPR003004 GspF/PilC family CWR44_RS10640 89629577fdc7e69c54dab2d694a4f03d 354 PRINTS PR00812 Bacterial general secretion pathway protein F signature 318 332 6.3E-7 T 28-03-2018 IPR003004 GspF/PilC family CWR44_RS10640 89629577fdc7e69c54dab2d694a4f03d 354 PRINTS PR00812 Bacterial general secretion pathway protein F signature 334 353 6.3E-7 T 28-03-2018 IPR003004 GspF/PilC family CWR44_RS10640 89629577fdc7e69c54dab2d694a4f03d 354 Pfam PF00482 Type II secretion system (T2SS), protein F 25 144 8.7E-9 T 28-03-2018 IPR018076 Type II secretion system F domain CWR44_RS10640 89629577fdc7e69c54dab2d694a4f03d 354 Pfam PF00482 Type II secretion system (T2SS), protein F 226 345 3.4E-14 T 28-03-2018 IPR018076 Type II secretion system F domain CWR44_RS05855 cd741634cb08da207b9999dd54f473f5 182 Pfam PF01380 SIS domain 36 135 8.7E-17 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CWR44_RS05855 cd741634cb08da207b9999dd54f473f5 182 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 8 182 3.3E-71 T 28-03-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 CWR44_RS05855 cd741634cb08da207b9999dd54f473f5 182 Gene3D G3DSA:3.40.50.10490 6 182 4.9E-38 T 28-03-2018 CWR44_RS05855 cd741634cb08da207b9999dd54f473f5 182 SUPERFAMILY SSF53697 8 181 6.88E-37 T 28-03-2018 CWR44_RS11955 4dc619a606e0c0689d1fd5a7d6a82b56 378 PIRSF PIRSF032178 1 378 1.9E-119 T 28-03-2018 IPR016991 Protein of unknown function UCP032178 CWR44_RS11955 4dc619a606e0c0689d1fd5a7d6a82b56 378 Pfam PF04286 Protein of unknown function (DUF445) 12 377 6.0E-71 T 28-03-2018 IPR007383 Protein of unknown function DUF445 CWR44_RS11590 a8c9ded26578b47e47fecd11bbfb1173 103 Gene3D G3DSA:3.40.30.10 2 103 2.0E-21 T 28-03-2018 CWR44_RS11590 a8c9ded26578b47e47fecd11bbfb1173 103 Pfam PF00085 Thioredoxin 13 93 1.4E-16 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CWR44_RS11590 a8c9ded26578b47e47fecd11bbfb1173 103 SUPERFAMILY SSF52833 9 101 1.3E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold CWR44_RS06360 9cdc497764b4f232337e7188fd45e034 219 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 29 213 1.9E-18 T 28-03-2018 IPR006214 Bax inhibitor 1-related CWR44_RS05065 85fe391297d5a770cdc6424a7af27970 120 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 5 113 3.5E-37 T 28-03-2018 IPR018745 Domain of unknown function DUF2294 CWR44_RS13195 368eb7814873da0930b7721fd8b9b644 31 Pfam PF13955 Toxin Fst, type I toxin-antitoxin system 6 26 5.7E-13 T 28-03-2018 IPR025882 Toxin Fst CWR44_RS13060 368eb7814873da0930b7721fd8b9b644 31 Pfam PF13955 Toxin Fst, type I toxin-antitoxin system 6 26 5.7E-13 T 28-03-2018 IPR025882 Toxin Fst CWR44_RS03765 25066c3f25e9894533e3217c0f4ef171 349 Pfam PF02687 FtsX-like permease family 261 344 5.0E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CWR44_RS00535 af92e5d47aae39bff570135e805ab76e 586 Pfam PF04183 IucA / IucC family 158 383 6.8E-50 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CWR44_RS00535 af92e5d47aae39bff570135e805ab76e 586 Pfam PF06276 Ferric iron reductase FhuF-like transporter 414 569 1.8E-25 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CWR44_RS07635 40653969be7dc2ed8e5679fabfbe8823 200 Pfam PF02517 CAAX protease self-immunity 105 185 7.5E-5 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR44_RS09360 1bf66b40353c21c02d02272c79c8e2a1 484 Pfam PF00324 Amino acid permease 14 470 1.6E-119 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CWR44_RS09360 1bf66b40353c21c02d02272c79c8e2a1 484 PIRSF PIRSF006060 1 483 2.6E-80 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CWR44_RS09360 1bf66b40353c21c02d02272c79c8e2a1 484 ProSitePatterns PS00218 Amino acid permeases signature. 39 70 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CWR44_RS09755 2ef91ff786200a65bfcdf465c55bef26 374 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 240 6.2E-53 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CWR44_RS09755 2ef91ff786200a65bfcdf465c55bef26 374 Pfam PF00149 Calcineurin-like phosphoesterase 1 214 5.3E-17 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CWR44_RS09755 2ef91ff786200a65bfcdf465c55bef26 374 SUPERFAMILY SSF56300 1 315 1.21E-51 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS09755 2ef91ff786200a65bfcdf465c55bef26 374 Gene3D G3DSA:3.60.21.10 74 264 9.9E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS09755 2ef91ff786200a65bfcdf465c55bef26 374 Gene3D G3DSA:3.60.21.10 1 73 2.8E-15 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CWR44_RS06390 438ab079f9c45ec42e9ca8cb97510747 203 Gene3D G3DSA:2.40.380.10 3 169 8.3E-20 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CWR44_RS06390 438ab079f9c45ec42e9ca8cb97510747 203 SUPERFAMILY SSF159234 1 162 5.49E-26 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CWR44_RS06390 438ab079f9c45ec42e9ca8cb97510747 203 Pfam PF04167 Protein of unknown function (DUF402) 61 129 5.9E-16 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CWR44_RS11680 96f92b3f0b6e75e6e6bc4674d010994c 395 Gene3D G3DSA:1.20.1250.20 4 179 3.1E-22 T 28-03-2018 CWR44_RS11680 96f92b3f0b6e75e6e6bc4674d010994c 395 SUPERFAMILY SSF103473 5 383 1.7E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CWR44_RS11680 96f92b3f0b6e75e6e6bc4674d010994c 395 Gene3D G3DSA:1.20.1250.20 194 395 4.2E-29 T 28-03-2018 CWR44_RS11680 96f92b3f0b6e75e6e6bc4674d010994c 395 Pfam PF07690 Major Facilitator Superfamily 10 224 2.2E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CWR44_RS06825 231adef5121f4db09e9c5eee24e79268 213 SUPERFAMILY SSF109604 3 188 2.73E-32 T 28-03-2018 CWR44_RS06825 231adef5121f4db09e9c5eee24e79268 213 Gene3D G3DSA:1.10.3210.10 1 213 3.8E-45 T 28-03-2018 CWR44_RS06825 231adef5121f4db09e9c5eee24e79268 213 Pfam PF12917 HD containing hydrolase-like enzyme 1 208 2.6E-84 T 28-03-2018 IPR027366 HD containing hydrolase-like enzyme CWR44_RS05870 d02fe81a3e7d96090b7e75b32ddc5d3f 126 PIRSF PIRSF032370 1 122 5.1E-59 T 28-03-2018 IPR016994 Uncharacterised conserved protein UCP032370, VraC CWR44_RS05615 38d35b195f22283b8f034855da28dc3d 455 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 42 92 3.7E-12 T 28-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CWR44_RS05615 38d35b195f22283b8f034855da28dc3d 455 Pfam PF01610 Transposase 164 417 3.0E-54 T 28-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CWR44_RS04990 bba1408d5ae38fd3a53db6639740bcf3 213 Pfam PF16560 Putative mobile pathogenicity island 1 213 4.2E-121 T 28-03-2018 IPR032351 Putative mobile pathogenicity island CWR44_RS00950 d5bdbb3c8b6ff699b9279e4855284865 182 PIRSF PIRSF016661 1 179 9.7E-36 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CWR44_RS00950 d5bdbb3c8b6ff699b9279e4855284865 182 Pfam PF02632 BioY family 29 170 5.1E-30 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CWR44_RS03815 b5aaae210d0f2893c45b0570b116050b 74 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 3 57 0.006 T 28-03-2018 IPR009907 Protein of unknown function DUF1447 CWR44_RS02900 467ee9859a7278f08682dcf03e472a94 697 Gene3D G3DSA:1.20.5.420 55 111 3.5E-7 T 28-03-2018 CWR44_RS11800 f6bdac5bff0e5e5b7d809565756aff2b 302 Gene3D G3DSA:1.20.120.350 4 257 7.2E-4 T 28-03-2018 CWR44_RS05230 2ff56a2155351e1cc5a1394d3e000dad 177 SUPERFAMILY SSF55729 2 160 2.52E-39 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS05230 2ff56a2155351e1cc5a1394d3e000dad 177 Pfam PF13302 Acetyltransferase (GNAT) domain 3 134 2.3E-19 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS05230 2ff56a2155351e1cc5a1394d3e000dad 177 Gene3D G3DSA:3.40.630.30 1 168 6.9E-33 T 28-03-2018 CWR44_RS09240 280c97072ba98a385445da85923ecc13 250 Pfam PF04233 Phage Mu protein F like protein 139 240 1.3E-9 T 28-03-2018 IPR006528 Phage head morphogenesis domain CWR44_RS09240 280c97072ba98a385445da85923ecc13 250 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 144 240 5.0E-23 T 28-03-2018 IPR006528 Phage head morphogenesis domain CWR44_RS07540 a1ec6583469270597e58e54d78742fd6 115 Hamap MF_01861 UPF0738 protein . 1 113 24.268 T 28-03-2018 IPR020908 Uncharacterised protein family UPF0738 CWR44_RS12500 154a4d9658fa10ac5a6ad279dc90c492 280 Pfam PF13349 Putative adhesin 46 280 1.1E-17 T 28-03-2018 IPR025164 Putative adhesin CWR44_RS10925 de072893ba9c86de2ff0fee84b835dac 250 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 45.563 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CWR44_RS10925 de072893ba9c86de2ff0fee84b835dac 250 Gene3D G3DSA:3.20.20.370 2 249 2.7E-105 T 28-03-2018 CWR44_RS10925 de072893ba9c86de2ff0fee84b835dac 250 Pfam PF03746 LamB/YcsF family 3 240 3.3E-102 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CWR44_RS10925 de072893ba9c86de2ff0fee84b835dac 250 SUPERFAMILY SSF88713 1 249 9.64E-101 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CWR44_RS02820 00df171d6be3f28f90df37da37ca84ba 319 Pfam PF13280 WYL domain 144 315 8.2E-28 T 28-03-2018 IPR026881 WYL domain CWR44_RS11435 e31315f3a602cfb0fd0191396b51c7d0 258 Pfam PF01925 Sulfite exporter TauE/SafE 12 246 1.6E-39 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CWR44_RS12845 fcc6324b8e004ce3c2386a57f827efcb 175 Pfam PF03703 Bacterial PH domain 73 147 6.7E-17 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CWR44_RS03920 1ff45b0dda7702ed5c46c4ddd0d397eb 350 Pfam PF13303 Phosphotransferase system, EIIC 15 347 1.6E-88 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS03160 f9628b0deea19235e264768f05fb4c39 234 Pfam PF06149 Protein of unknown function (DUF969) 3 220 5.4E-87 T 28-03-2018 IPR010374 Protein of unknown function DUF969 CWR44_RS05910 b9063a91efdd8257ce57c5e26a23dd31 150 Pfam PF12821 Threonine/Serine exporter, ThrE 7 133 1.7E-38 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CWR44_RS05055 fc674415d77625e3d50d7dfbc9f63a09 499 Pfam PF00361 Proton-conducting membrane transporter 119 397 1.6E-55 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CWR44_RS05055 fc674415d77625e3d50d7dfbc9f63a09 499 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 68 93 2.3E-11 T 28-03-2018 CWR44_RS05055 fc674415d77625e3d50d7dfbc9f63a09 499 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 296 308 2.3E-11 T 28-03-2018 CWR44_RS05055 fc674415d77625e3d50d7dfbc9f63a09 499 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 230 256 2.3E-11 T 28-03-2018 CWR44_RS05055 fc674415d77625e3d50d7dfbc9f63a09 499 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 208 229 2.3E-11 T 28-03-2018 CWR44_RS11905 c8a3d61424ffe574464f6dc2def97935 407 PIRSF PIRSF037259 3 407 6.5E-102 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CWR44_RS11905 c8a3d61424ffe574464f6dc2def97935 407 Pfam PF05975 Bacterial ABC transporter protein EcsB 7 386 3.8E-106 T 28-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CWR44_RS09165 b00dc113e90d0836738f0c49c5e8b99f 76 Gene3D G3DSA:2.60.40.10 3 74 1.7E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWR44_RS04400 be2fc7dd6f2b3b462999183516eb5ede 109 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 8 106 3.4E-19 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CWR44_RS10090 01812f6b0bef5ba870542b2e0b9fa5d6 167 SUPERFAMILY SSF55729 2 164 7.39E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS10090 01812f6b0bef5ba870542b2e0b9fa5d6 167 Pfam PF00583 Acetyltransferase (GNAT) family 32 141 1.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS10090 01812f6b0bef5ba870542b2e0b9fa5d6 167 Gene3D G3DSA:3.40.630.30 1 167 4.0E-24 T 28-03-2018 CWR44_RS08275 7448282bf31e90237d59338a07073a36 44 Pfam PF05480 Staphylococcus haemolytic protein 1 43 4.1E-20 T 28-03-2018 IPR008846 Staphylococcal hemolytic protein family GO:0009405 CWR44_RS00485 bbf1b25a3b7a18b058675bd24c2cce5b 227 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 26 225 3.2E-52 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CWR44_RS00485 bbf1b25a3b7a18b058675bd24c2cce5b 227 Pfam PF03006 Haemolysin-III related 25 220 2.6E-30 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CWR44_RS01685 cc383fb9df580890effc66d2f1ff20e1 277 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 53 246 4.6E-40 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CWR44_RS01685 cc383fb9df580890effc66d2f1ff20e1 277 Pfam PF02096 60Kd inner membrane protein 54 245 1.8E-34 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CWR44_RS08070 f30b5c8c05cf4faf386dcc2ab2cbea8f 63 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 3 50 7.6E-21 T 28-03-2018 IPR019241 Protein of unknown function DUF2197 CWR44_RS04135 98dfc96c3da9e7c37b29ff46eb20d96f 86 Pfam PF02583 Metal-sensitive transcriptional repressor 4 82 7.3E-22 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CWR44_RS06830 b329a1ab9d08891fd833f1ed6d51d555 75 Pfam PF09964 Uncharacterized protein conserved in bacteria (DUF2198) 3 74 3.2E-31 T 28-03-2018 IPR019242 Protein of unknown function DUF2198 CWR44_RS04480 1e72d57318118249e5acfeda728d60fc 120 Pfam PF11345 Protein of unknown function (DUF3147) 9 118 9.3E-42 T 28-03-2018 IPR021493 Protein of unknown function DUF3147 CWR44_RS02980 7dcdb19e04c2994f88358c65a4c11601 445 Hamap MF_01473 Glycosyltransferase stabilizing protein Gtf2 [gtf2]. 1 440 35.472 T 28-03-2018 IPR014268 Glycosyltransferase-stabilising protein Gtf2 GO:0031647 CWR44_RS02980 7dcdb19e04c2994f88358c65a4c11601 445 TIGRFAM TIGR02919 TIGR02919: accessory Sec system glycosyltransferase GtfB 1 439 2.6E-197 T 28-03-2018 IPR014268 Glycosyltransferase-stabilising protein Gtf2 GO:0031647 CWR44_RS12505 4db39593b6c9302c8a02c7b95d52ef6c 185 Pfam PF08006 Protein of unknown function (DUF1700) 1 181 1.1E-54 T 28-03-2018 IPR012963 Protein of unknown function DUF1700 CWR44_RS07030 44a0d9e594edc7e362dd5d0f1703c1f0 62 Gene3D G3DSA:1.20.1070.10 1 62 3.3E-4 T 28-03-2018 CWR44_RS07055 8de2084ba3bf724dfd425955e691eedb 205 Pfam PF01810 LysE type translocator 15 197 2.2E-26 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CWR44_RS08865 e3d93c330113b45ac99b8292d933ef46 203 Pfam PF05908 Poly-gamma-glutamate hydrolase 4 194 1.5E-61 T 28-03-2018 IPR008585 Poly-gamma-glutamate hydrolase CWR44_RS04405 58cead1ddde4e5458d168ed1712b7b47 231 Pfam PF03591 AzlC protein 16 156 3.1E-38 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease CWR44_RS04740 ff148957d925f95c4a0076cb1c306993 130 SUPERFAMILY SSF55729 10 114 9.31E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CWR44_RS04740 ff148957d925f95c4a0076cb1c306993 130 Pfam PF00583 Acetyltransferase (GNAT) family 20 110 6.1E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CWR44_RS04740 ff148957d925f95c4a0076cb1c306993 130 Gene3D G3DSA:3.40.630.30 4 130 9.8E-22 T 28-03-2018 CWR44_RS07320 8443910388585644eafb9809a585d010 142 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 11 133 8.0E-30 T 28-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CWR44_RS07320 8443910388585644eafb9809a585d010 142 TIGRFAM TIGR00943 2a6301s02: monovalent cation:proton antiporter 28 134 3.9E-42 T 28-03-2018 IPR005281 Monovalent cation:proton antiporter, subunit B GO:0006812|GO:0008324|GO:0016021 CWR44_RS02445 bbb2985fae9a10aeb199dd259ca58906 560 Gene3D G3DSA:3.90.350.10 262 498 2.1E-7 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CWR44_RS02445 bbb2985fae9a10aeb199dd259ca58906 560 Pfam PF05598 Transposase domain (DUF772) 49 117 1.6E-14 T 28-03-2018 IPR008490 Transposase InsH, N-terminal CWR44_RS02445 bbb2985fae9a10aeb199dd259ca58906 560 Pfam PF01609 Transposase DDE domain 264 515 8.6E-38 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CWR44_RS00405 5c4df8a462f31a3fdeb9cd30d7c2d075 310 Pfam PF07949 YbbR-like protein 229 307 5.5E-15 T 28-03-2018 IPR012505 YbbR-like CWR44_RS00405 5c4df8a462f31a3fdeb9cd30d7c2d075 310 Pfam PF07949 YbbR-like protein 142 220 2.3E-8 T 28-03-2018 IPR012505 YbbR-like CWR44_RS00405 5c4df8a462f31a3fdeb9cd30d7c2d075 310 Pfam PF07949 YbbR-like protein 47 127 2.3E-10 T 28-03-2018 IPR012505 YbbR-like CWR44_RS00405 5c4df8a462f31a3fdeb9cd30d7c2d075 310 Gene3D G3DSA:2.60.40.10 111 223 6.7E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CWR44_RS05580 7bccf97c6165cf0d0ff3f3d95657f74f 175 Pfam PF05991 YacP-like NYN domain 6 169 1.1E-48 T 28-03-2018 IPR010298 Protein of unknown function DUF901 CWR44_RS10550 6e40845a5bc93fa6e037babd1d9c27cf 119 Pfam PF03780 Asp23 family, cell envelope-related function 12 116 1.9E-25 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CWR44_RS02080 7742960d6f9a8f78ff04f7d19f7c56f9 348 Pfam PF13303 Phosphotransferase system, EIIC 31 332 1.3E-41 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS02715 ead4f334f529e754dc5b23827cd96667 388 Pfam PF04932 O-Antigen ligase 188 326 6.7E-10 T 28-03-2018 IPR007016 O-antigen ligase-related CWR44_RS01000 e8834d77a0e887df062373fdab0724d3 468 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 3 459 2.4E-128 T 28-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CWR44_RS01000 e8834d77a0e887df062373fdab0724d3 468 Pfam PF03553 Na+/H+ antiporter family 157 454 8.9E-58 T 28-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CWR44_RS06220 216d81c46695f01a31a1821e1715b80e 270 Pfam PF01061 ABC-2 type transporter 17 227 3.6E-12 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CWR44_RS07200 cf5944f60329e4ab3092dfb659915a81 88 Pfam PF11256 Protein of unknown function (DUF3055) 6 84 4.5E-34 T 28-03-2018 IPR021415 Protein of unknown function DUF3055 CWR44_RS06125 aa60b96f43bf455abc3d2182d26c2cc5 308 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 144 2.7E-36 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CWR44_RS06125 aa60b96f43bf455abc3d2182d26c2cc5 308 Pfam PF04657 Putative inner membrane exporter, YdcZ 163 304 2.2E-36 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CWR44_RS07940 ec9e19932ee0fee2564da06f3ae24070 450 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 435 3.0E-130 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CWR44_RS07940 ec9e19932ee0fee2564da06f3ae24070 450 PIRSF PIRSF006446 1 449 6.1E-131 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CWR44_RS01320 ab3c4d67344a6110f7f8a29fc183b982 150 Pfam PF11457 Protein of unknown function (DUF3021) 4 147 9.5E-27 T 28-03-2018 IPR021560 Protein of unknown function DUF3021 CWR44_RS06450 c87c4510a17d575c77f15e63fae4daf8 291 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 280 17.389 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWR44_RS06450 c87c4510a17d575c77f15e63fae4daf8 291 Pfam PF02673 Bacitracin resistance protein BacA 10 274 1.4E-78 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWR44_RS06450 c87c4510a17d575c77f15e63fae4daf8 291 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 10 272 1.7E-81 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CWR44_RS03890 85faecf9494b422124de72264e9eb891 355 Pfam PF01757 Acyltransferase family 10 321 1.0E-22 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CWR44_RS09460 3eaa247619e4bea18942c96f34d16b7e 93 Pfam PF06531 Protein of unknown function (DUF1108) 10 88 5.9E-9 T 28-03-2018 IPR009494 Protein of unknown function DUF1108 CWR44_RS03205 c07a21b259c61431cd85b5cb55359f46 272 Pfam PF02517 CAAX protease self-immunity 169 256 4.0E-15 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR44_RS02570 a9637550547e7bc6b51dabdaf1af62b5 541 ProSitePatterns PS01303 BCCT family of transporters signature. 320 329 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CWR44_RS02570 a9637550547e7bc6b51dabdaf1af62b5 541 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 51 507 4.7E-143 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CWR44_RS02570 a9637550547e7bc6b51dabdaf1af62b5 541 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 12 506 4.6E-153 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CWR44_RS08530 829109dc4df172835e3b7718f910ef1f 122 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 3.4E-31 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CWR44_RS01615 f0100666a3b7f88aa17e4cdc16b50173 126 Pfam PF04138 GtrA-like protein 12 123 1.3E-23 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CWR44_RS08350 52765c7b67483766c0ed8d4185a939eb 197 Pfam PF04472 Cell division protein SepF 110 180 5.2E-28 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CWR44_RS08350 52765c7b67483766c0ed8d4185a939eb 197 Hamap MF_01197 Cell division protein SepF [sepF]. 1 188 19.828 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 CWR44_RS08105 60c5245e85c5019ee5a52cbd10d49630 153 Gene3D G3DSA:1.20.120.80 1 137 4.5E-13 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CWR44_RS08105 60c5245e85c5019ee5a52cbd10d49630 153 Pfam PF04238 Protein of unknown function (DUF420) 6 134 1.4E-37 T 28-03-2018 IPR007352 Protein of unknown function DUF420 CWR44_RS00120 10927ffa653b0c97baa99eb00c8d98f9 147 Pfam PF14183 YwpF-like protein 2 131 5.0E-46 T 28-03-2018 IPR025573 YwpF-like protein CWR44_RS09310 5f4cd3a4663b8e9735793dcef392ff91 63 Gene3D G3DSA:1.10.3470.10 6 63 6.3E-4 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CWR44_RS07740 8b166cd26bd3466dc1736eb580ca90bf 175 PIRSF PIRSF005859 13 169 3.7E-34 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CWR44_RS07740 8b166cd26bd3466dc1736eb580ca90bf 175 Pfam PF03073 TspO/MBR family 29 163 3.5E-36 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CWR44_RS06130 44a5cebab4b32530ea3e7022187f1049 73 Pfam PF11148 Protein of unknown function (DUF2922) 3 69 2.5E-16 T 28-03-2018 IPR021321 Protein of unknown function DUF2922 CWR44_RS05255 16feac9aca0505c3034e22056bbb73b7 267 Pfam PF04468 PSP1 C-terminal conserved region 61 146 2.0E-27 T 28-03-2018 IPR007557 PSP1, C-terminal CWR44_RS09420 8e0848b18aaf11aac32c643641128fcb 150 Pfam PF06114 IrrE N-terminal-like domain 48 135 2.0E-7 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CWR44_RS04060 742a126a5f7c1faff5d1d7e9f25e286c 26 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 4 26 4.6E-7 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CWR44_RS04060 742a126a5f7c1faff5d1d7e9f25e286c 26 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 4 26 4.0E-7 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CWR44_RS10630 3cd97b09b306dc9faee2aa95227e618e 147 PIRSF PIRSF021292 3 145 8.7E-32 T 28-03-2018 IPR016785 ComG operon protein 4 GO:0030420 CWR44_RS02860 c08cf555a009f741c52f0902e3821e46 191 Gene3D G3DSA:3.30.1450.10 110 184 1.6E-4 T 28-03-2018 CWR44_RS03380 757be6b872d294dd26c14d3b36bd96ef 278 Pfam PF02517 CAAX protease self-immunity 121 215 4.5E-18 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR44_RS00550 1de426b8957a4a971377c2c7c2931a0b 176 Gene3D G3DSA:2.130.10.10 3 175 1.1E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CWR44_RS00550 1de426b8957a4a971377c2c7c2931a0b 176 Pfam PF03780 Asp23 family, cell envelope-related function 44 149 4.0E-34 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CWR44_RS01010 1f7dbbe534182ff4b50821226aaae239 142 Gene3D G3DSA:1.20.1250.20 6 131 0.001 T 28-03-2018 CWR44_RS01010 1f7dbbe534182ff4b50821226aaae239 142 Pfam PF09685 Domain of unknown function (DUF4870) 22 141 9.5E-19 T 28-03-2018 IPR019109 Protein of unknown function DUF4870 CWR44_RS04340 992291b2a2779f6a3427e08804c61bfc 263 Pfam PF09648 YycH protein 33 254 2.1E-46 T 28-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 CWR44_RS09260 559d02a4b3f8a592d743c1000514960d 99 Pfam PF14265 Domain of unknown function (DUF4355) 26 86 1.5E-16 T 28-03-2018 IPR025580 Protein of unknown function DUF4355 CWR44_RS09180 f5ab846ba9fff2ec620189f361d4ae0a 275 Pfam PF05709 Phage tail protein 30 275 6.7E-28 T 28-03-2018 IPR008841 Siphovirus-type tail component CWR44_RS01565 d16e9c2d886e23f02178b4051010e030 119 Pfam PF14729 Domain of unknown function with cystatin-like fold (DUF4467) 23 117 7.1E-31 T 28-03-2018 IPR028075 Domain of unknown function with cystatin-like fold DUF4467 CWR44_RS09690 80780a5a1ff6b81c5188620c2c36a235 134 Pfam PF12691 Minor capsid protein from bacteriophage 7 129 3.8E-6 T 28-03-2018 IPR024411 Minor capsid protein, bacteriophage CWR44_RS05030 871bd23b8108bbe503e5a6e3631ccc1f 435 Pfam PF02386 Cation transport protein 32 418 4.1E-48 T 28-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CWR44_RS07515 58249ed4963de9b7847f4843dfc2b3b9 319 PIRSF PIRSF007487 1 318 8.4E-64 T 28-03-2018 IPR021176 Competence-induced protein CoiA CWR44_RS07515 58249ed4963de9b7847f4843dfc2b3b9 319 Pfam PF06054 Competence protein CoiA-like family 1 288 2.5E-34 T 28-03-2018 IPR010330 Competence-induced protein CoiA-like CWR44_RS10050 ec3c6b5924105cf7eb5e618e8a62eba2 268 SUPERFAMILY SSF54593 2 119 3.64E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS10050 ec3c6b5924105cf7eb5e618e8a62eba2 268 Gene3D G3DSA:3.10.180.10 126 261 0.045 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS10050 ec3c6b5924105cf7eb5e618e8a62eba2 268 Gene3D G3DSA:3.10.180.10 1 125 1.7E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CWR44_RS05630 2e9ec2fd07f43316d2711d732be41d43 202 SUPERFAMILY SSF53335 6 200 1.06E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CWR44_RS05630 2e9ec2fd07f43316d2711d732be41d43 202 Gene3D G3DSA:3.40.50.150 19 202 6.8E-31 T 28-03-2018 CWR44_RS05630 2e9ec2fd07f43316d2711d732be41d43 202 Pfam PF05175 Methyltransferase small domain 27 198 6.6E-53 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CWR44_RS09735 1a14f93b51ca18f2170ea128a2237b1a 157 Gene3D G3DSA:1.20.120.570 2 132 6.7E-4 T 28-03-2018 CWR44_RS07000 e4386e8c975356db398e934d7e53a1a0 248 Pfam PF05908 Poly-gamma-glutamate hydrolase 45 238 1.6E-68 T 28-03-2018 IPR008585 Poly-gamma-glutamate hydrolase CWR44_RS04650 301c95c06fc56ae1b477d1e014b5b678 82 Pfam PF04226 Transglycosylase associated protein 33 77 5.1E-10 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CWR44_RS12335 43f8e508dad90a7d98d071608f9d6582 329 Pfam PF06081 Aromatic acid exporter family member 1 9 147 1.2E-29 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CWR44_RS06070 0bdbcb7def1feb43e7ee61226d40580f 165 Pfam PF05656 Protein of unknown function (DUF805) 12 162 5.7E-18 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 CWR44_RS01725 ab346710cfebe26d91ecbf604a00aee1 151 Pfam PF03788 LrgA family 35 126 8.1E-24 T 28-03-2018 IPR005538 LrgA/CidA family GO:0016021 CWR44_RS11765 4e2cfeecb4c91568e7468a29cb02002a 148 Pfam PF06338 ComK protein 22 145 1.2E-6 T 28-03-2018 IPR010461 Competence protein ComK GO:0030420 CWR44_RS04310 25332eea3df11f4d394a3da85cb3a020 366 SUPERFAMILY SSF56672 32 364 8.23E-41 T 28-03-2018 CWR44_RS04310 25332eea3df11f4d394a3da85cb3a020 366 Gene3D G3DSA:3.30.70.370 121 358 9.9E-16 T 28-03-2018 CWR44_RS06150 ad52463b25c7851190b98e9fc07fffee 141 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 7 131 1.9E-33 T 28-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CWR44_RS07910 08608dd16d478e64ea2b268689885119 180 Pfam PF05128 Domain of unknown function (DUF697) 37 155 1.9E-5 T 28-03-2018 IPR021147 Protein of unknown function DUF697 CWR44_RS06765 8a11ba3a085ef6430650b163133cb917 253 Pfam PF06738 Putative threonine/serine exporter 15 252 1.4E-69 T 28-03-2018 IPR010619 Putative threonine/serine exporter CWR44_RS03350 6932f757b75ad1e42611362cc95b8512 343 Pfam PF13303 Phosphotransferase system, EIIC 28 335 2.7E-62 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CWR44_RS03745 89a2111b96b5c169ba594fd6397bfc51 119 Gene3D G3DSA:3.60.15.10 11 115 2.0E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS03745 89a2111b96b5c169ba594fd6397bfc51 119 SUPERFAMILY SSF56281 2 109 1.37E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CWR44_RS03710 00fea3460dd991c93bf8c30073f14494 287 Gene3D G3DSA:1.10.10.10 1 82 4.4E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS06910 478a5146d6c98650ce7551818baa4969 243 Pfam PF16228 Domain of unknown function (DUF4887) 42 180 7.1E-14 T 28-03-2018 IPR032615 Protein of unknown function DUF4887 CWR44_RS07980 9a857ebbc590018317dae7c374c59f66 207 Pfam PF10368 Putative cell-wall binding lipoprotein 12 206 9.6E-46 T 28-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like CWR44_RS07980 9a857ebbc590018317dae7c374c59f66 207 SUPERFAMILY SSF140423 21 204 6.15E-49 T 28-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like CWR44_RS07980 9a857ebbc590018317dae7c374c59f66 207 Gene3D G3DSA:1.20.120.570 10 207 2.8E-37 T 28-03-2018 CWR44_RS01605 f4791c58fe025a9735d8a24d58643ccb 192 Gene3D G3DSA:1.10.530.10 103 192 2.6E-4 T 28-03-2018 CWR44_RS05525 b5bfc9417db652f5d423a4fa70d7c836 153 PIRSF PIRSF010607 1 153 1.5E-63 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CWR44_RS05525 b5bfc9417db652f5d423a4fa70d7c836 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 148 1.0E-55 T 28-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CWR44_RS06420 a72206eb3ddeff24f1954ed08e82bfe3 162 Gene3D G3DSA:1.20.5.400 20 143 5.0E-6 T 28-03-2018 CWR44_RS03605 043d92d9acd9d88cef80cd635a676ca9 183 Pfam PF05656 Protein of unknown function (DUF805) 18 176 7.4E-19 T 28-03-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 CWR44_RS05500 c8932fdfca13d4a86d61677fe25dda03 118 Pfam PF07681 DoxX 4 84 1.4E-18 T 28-03-2018 IPR032808 DoxX family CWR44_RS00335 0c08f46e525eb3f90cab26928888cd7e 131 Pfam PF04134 Protein of unknown function, DUF393 4 110 6.4E-16 T 28-03-2018 IPR007263 Protein of unknown function DUF393 CWR44_RS04890 f63b0d04d725b3bb2b65b6f57ab21542 216 Gene3D G3DSA:1.10.10.10 1 148 1.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CWR44_RS01810 f4e8cda756279bf45c52cdba4fa5c306 260 Pfam PF02517 CAAX protease self-immunity 157 248 5.7E-5 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CWR44_RS07880 9348ab81c71c75af87584687d1b01a97 269 Pfam PF02361 Cobalt transport protein 21 218 2.4E-21 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CWR44_RS05350 14b400da9d564e8f816cf80f5bba18e0 537 Pfam PF01943 Polysaccharide biosynthesis protein 37 320 2.4E-27 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CWR44_RS05350 14b400da9d564e8f816cf80f5bba18e0 537 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 373 512 2.5E-20 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain