locus-tag	class	description
Sta0113_RS00005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Sta0113_RS00035	COG3091	SprT-like family
Sta0113_RS00040	COG2183	response to ionizing radiation
Sta0113_RS00045	COG1191	sigma factor activity
Sta0113_RS00060	COG2208	phosphoserine phosphatase activity
Sta0113_RS00065	COG2337	Toxic component of a toxin-antitoxin (TA) module
Sta0113_RS00075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Sta0113_RS00080	COG0736	holo-[acyl-carrier-protein] synthase activity
Sta0113_RS00090	COG3428	Bacterial PH domain
Sta0113_RS00100	COG0513	Belongs to the DEAD box helicase family
Sta0113_RS00105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Sta0113_RS00110	COG1181	Belongs to the D-alanine--D-alanine ligase family
Sta0113_RS00115	COG0772	Belongs to the SEDS family
Sta0113_RS00130	COG1937	Protein conserved in bacteria
Sta0113_RS00135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Sta0113_RS00140	COG1418	mRNA catabolic process
Sta0113_RS00145	COG0706	membrane insertase activity
Sta0113_RS00150	COG0352	thiamine-phosphate diphosphorylase activity
Sta0113_RS00155	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Sta0113_RS00165	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Sta0113_RS00170	COG1388	LysM domain
Sta0113_RS00175	COG0629	single-stranded DNA binding
Sta0113_RS00185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Sta0113_RS00190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Sta0113_RS00200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Sta0113_RS00205	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Sta0113_RS00210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Sta0113_RS00215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Sta0113_RS00220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Sta0113_RS00225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Sta0113_RS00230	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Sta0113_RS00235	COG0356	it plays a direct role in the translocation of protons across the membrane
Sta0113_RS00245	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Sta0113_RS00250	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Sta0113_RS00255	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Sta0113_RS00260	COG4475	Protein of unknown function (DUF436)
Sta0113_RS00265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sta0113_RS00270	COG0009	L-threonylcarbamoyladenylate synthase
Sta0113_RS00275	COG2890	protein-(glutamine-N5) methyltransferase activity
Sta0113_RS00280	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Sta0113_RS00285	COG1435	thymidine kinase activity
Sta0113_RS00290	COG0254	rRNA binding
Sta0113_RS00295	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Sta0113_RS00300	COG1012	belongs to the aldehyde dehydrogenase family
Sta0113_RS00310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Sta0113_RS00315	COG0191	fructose-bisphosphate aldolase activity
Sta0113_RS00325	COG0504	CTP synthase activity
Sta0113_RS00340	COG5146	pantothenate kinase activity
Sta0113_RS00360	COG1854	S-ribosylhomocysteine lyase activity
Sta0113_RS00370	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Sta0113_RS00375	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Sta0113_RS00380	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Sta0113_RS00385	COG0813	purine-nucleoside phosphorylase activity
Sta0113_RS00390	COG0783	Belongs to the Dps family
Sta0113_RS00405	COG1482	cell wall glycoprotein biosynthetic process
Sta0113_RS00410	COG0702	epimerase
Sta0113_RS00415	COG0640	Transcriptional regulator
Sta0113_RS00435	COG0561	phosphatase activity
Sta0113_RS00440	COG1119	ATPase activity
Sta0113_RS00450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Sta0113_RS00460	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Sta0113_RS00510	COG0489	protein tyrosine kinase activity
Sta0113_RS00525	COG1272	protein, Hemolysin III
Sta0113_RS00530	COG4284	Utp--glucose-1-phosphate uridylyltransferase
Sta0113_RS00535	COG1988	membrane-bound metal-dependent
Sta0113_RS00540	COG2329	Antibiotic biosynthesis monooxygenase
Sta0113_RS00545	COG3314	Sporulation integral membrane protein YlbJ
Sta0113_RS00555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Sta0113_RS00560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Sta0113_RS00565	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Sta0113_RS00570	COG3457	Alanine racemase
Sta0113_RS00575	COG4264	IucA IucC family
Sta0113_RS00580	COG4264	IucA IucC family
Sta0113_RS00585	COG1302	Protein conserved in bacteria
Sta0113_RS00600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Sta0113_RS00605	COG0604	alcohol dehydrogenase
Sta0113_RS00610	COG2130	NADP-dependent
Sta0113_RS00615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Sta0113_RS00625	COG2723	6-phospho-beta-galactosidase activity
Sta0113_RS00630	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Sta0113_RS00630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Sta0113_RS00635	COG1447	Phosphotransferase system cellobiose-specific component IIA
Sta0113_RS00640	COG3684	Belongs to the aldolase LacD family
Sta0113_RS00645	COG1105	Belongs to the carbohydrate kinase PfkB family
Sta0113_RS00650	COG0698	ribose 5-phosphate isomerase
Sta0113_RS00655	COG0698	ribose 5-phosphate isomerase
Sta0113_RS00660	COG1349	DNA-binding transcription factor activity
Sta0113_RS00665	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Sta0113_RS00670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Sta0113_RS00675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Sta0113_RS00680	COG0101	tRNA pseudouridine synthase activity
Sta0113_RS00695	COG1122	ATPase activity
Sta0113_RS00700	COG0203	ribosomal protein L17
Sta0113_RS00705	COG0202	RNA polymerase activity
Sta0113_RS00715	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Sta0113_RS00720	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Sta0113_RS00725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Sta0113_RS00730	COG0563	adenylate kinase activity
Sta0113_RS00735	COG0201	protein transport
Sta0113_RS00740	COG0200	Binds to the 23S rRNA
Sta0113_RS00745	COG1841	ribosomal large subunit assembly
Sta0113_RS00750	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Sta0113_RS00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Sta0113_RS00760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Sta0113_RS00765	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Sta0113_RS00775	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Sta0113_RS00780	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Sta0113_RS00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Sta0113_RS00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Sta0113_RS00800	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Sta0113_RS00805	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Sta0113_RS00810	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Sta0113_RS00815	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Sta0113_RS00820	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Sta0113_RS00825	COG0089	rRNA binding
Sta0113_RS00830	COG0088	Forms part of the polypeptide exit tunnel
Sta0113_RS00835	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Sta0113_RS00850	COG2252	PERMEase
Sta0113_RS00855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Sta0113_RS00855	COG0551	DNA topoisomerase type I activity
Sta0113_RS00860	COG4975	Glucose uptake
Sta0113_RS00885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Sta0113_RS00890	COG2348	transferase activity, transferring amino-acyl groups
Sta0113_RS00915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Sta0113_RS00920	COG0746	molybdenum cofactor guanylyltransferase activity
Sta0113_RS00945	COG0315	cyclic pyranopterin monophosphate synthase activity
Sta0113_RS00950	COG0521	Mo-molybdopterin cofactor biosynthetic process
Sta0113_RS00955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Sta0113_RS00960	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Sta0113_RS00965	COG4149	molybdate abc transporter
Sta0113_RS00970	COG0725	ABC transporter, periplasmic molybdate-binding protein
Sta0113_RS00975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Sta0113_RS00985	COG1268	BioY protein
Sta0113_RS00995	COG1960	acyl-CoA dehydrogenase activity
Sta0113_RS01010	COG2207	Transcriptional regulator
Sta0113_RS01015	COG3942	CHAP domain
Sta0113_RS01020	COG1757	Na H antiporter
Sta0113_RS01030	COG3942	CHAP domain
Sta0113_RS01035	COG2076	Multidrug Resistance protein
Sta0113_RS01040	COG2076	Multidrug Resistance protein
Sta0113_RS01045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Sta0113_RS01070	COG3383	formate dehydrogenase (NAD+) activity
Sta0113_RS01075	COG1316	TRANSCRIPTIONal
Sta0113_RS01085	COG2378	regulation of single-species biofilm formation
Sta0113_RS01100	COG1113	amino acid transport
Sta0113_RS01120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Sta0113_RS01125	COG0385	Bile acid
Sta0113_RS01135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Sta0113_RS01135	COG1263	PTS System
Sta0113_RS01140	COG1737	Transcriptional regulator
Sta0113_RS01155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Sta0113_RS01160	COG1028	Short-chain dehydrogenase reductase Sdr
Sta0113_RS01165	COG1473	amidohydrolase
Sta0113_RS01170	COG0010	Belongs to the arginase family
Sta0113_RS01175	COG1266	CAAX protease self-immunity
Sta0113_RS01180	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Sta0113_RS01185	COG2258	MOSC domain
Sta0113_RS01190	COG2017	converts alpha-aldose to the beta-anomer
Sta0113_RS01195	COG1742	UPF0060 membrane protein
Sta0113_RS01200	COG2094	Belongs to the DNA glycosylase MPG family
Sta0113_RS01205	COG1304	FMN binding
Sta0113_RS01210	COG0598	Magnesium transport protein CorA
Sta0113_RS01235	COG2814	Major facilitator Superfamily
Sta0113_RS01240	COG1566	PFAM secretion protein HlyD family protein
Sta0113_RS01250	COG2814	Major facilitator Superfamily
Sta0113_RS01255	COG4640	response to antibiotic
Sta0113_RS01270	COG1136	(ABC) transporter
Sta0113_RS01275	COG0577	efflux transmembrane transporter activity
Sta0113_RS01280	COG0745	RESPONSE REGULATOR receiver
Sta0113_RS01285	COG5002	protein histidine kinase activity
Sta0113_RS01285	COG3850	Histidine kinase
Sta0113_RS01290	COG0579	oxidoreductase
Sta0113_RS01295	COG0297	glycogen (starch) synthase activity
Sta0113_RS01300	COG1620	l-lactate permease
Sta0113_RS01315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Sta0113_RS01320	COG0805	protein transport
Sta0113_RS01325	COG0672	)-iron permease
Sta0113_RS01335	COG2822	iron ion transport
Sta0113_RS01340	COG0604	alcohol dehydrogenase
Sta0113_RS01345	COG4372	Transposase
Sta0113_RS01345	COG1196	nuclear chromosome segregation
Sta0113_RS01345	COG1511	domain protein
Sta0113_RS01380	COG1309	transcriptional regulator
Sta0113_RS01390	COG1263	PTS System
Sta0113_RS01390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Sta0113_RS01425	COG1846	Transcriptional regulator
Sta0113_RS01435	COG2223	nitrite transmembrane transporter activity
Sta0113_RS01440	COG2197	response regulator
Sta0113_RS01445	COG4585	Histidine kinase
Sta0113_RS01455	COG2181	nitrate reductase activity
Sta0113_RS01465	COG1140	nitrate reductase beta subunit
Sta0113_RS01470	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Sta0113_RS01480	COG2146	nitrite reductase [NAD(P)H] activity
Sta0113_RS01485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Sta0113_RS01510	COG2353	YceI-like domain
Sta0113_RS01530	COG2030	dehydratase
Sta0113_RS01535	COG1126	abc transporter atp-binding protein
Sta0113_RS01540	COG0765	amino acid transport
Sta0113_RS01545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Sta0113_RS01550	COG2814	Major facilitator Superfamily
Sta0113_RS01560	COG0588	phosphoglycerate mutase activity
Sta0113_RS01565	COG1388	LysM domain
Sta0113_RS01570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Sta0113_RS01585	COG1929	Belongs to the glycerate kinase type-1 family
Sta0113_RS01595	COG2814	Major facilitator Superfamily
Sta0113_RS01600	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
Sta0113_RS01615	COG1113	amino acid transport
Sta0113_RS01620	COG0025	NhaP-type Na H and K H
Sta0113_RS01625	COG0531	amino acid
Sta0113_RS01635	COG0706	membrane insertase activity
Sta0113_RS01645	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Sta0113_RS01655	COG3275	phosphorelay sensor kinase activity
Sta0113_RS01660	COG3279	Response regulator of the LytR AlgR family
Sta0113_RS01665	COG1380	Effector of murein hydrolase LrgA
Sta0113_RS01670	COG1346	cytolysis
Sta0113_RS01675	COG1174	glycine betaine transport
Sta0113_RS01695	COG1063	alcohol dehydrogenase
Sta0113_RS01700	COG0531	amino acid
Sta0113_RS01705	COG2272	Belongs to the type-B carboxylesterase lipase family
Sta0113_RS01710	COG2814	Major facilitator Superfamily
Sta0113_RS01715	COG0390	transport system, permease component
Sta0113_RS01720	COG4619	ABC transporter
Sta0113_RS01735	COG0069	glutamate synthase activity
Sta0113_RS01745	COG1363	Peptidase, m42
Sta0113_RS01750	COG1028	Short-chain dehydrogenase reductase Sdr
Sta0113_RS01760	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Sta0113_RS01765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Sta0113_RS01770	COG4221	oxidoreductase activity
Sta0113_RS01825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Sta0113_RS01830	COG2610	gluconate transmembrane transporter activity
Sta0113_RS01835	COG1070	Carbohydrate kinase
Sta0113_RS01840	COG1802	Transcriptional regulator
Sta0113_RS01855	COG2357	RelA SpoT domain protein
Sta0113_RS01860	COG4876	unkown
Sta0113_RS01880	COG2271	Major facilitator Superfamily
Sta0113_RS01885	COG0352	thiamine-phosphate diphosphorylase activity
Sta0113_RS01890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Sta0113_RS01900	COG2022	thiamine diphosphate biosynthetic process
Sta0113_RS01905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Sta0113_RS01910	COG0586	Pfam SNARE associated Golgi protein
Sta0113_RS01915	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
Sta0113_RS01925	COG3949	Membrane
Sta0113_RS01930	COG1012	belongs to the aldehyde dehydrogenase family
Sta0113_RS01945	COG2514	catechol 2,3-dioxygenase activity
Sta0113_RS01955	COG1012	belongs to the aldehyde dehydrogenase family
Sta0113_RS01960	COG0778	Nitroreductase
Sta0113_RS01970	COG0561	phosphatase activity
Sta0113_RS01975	COG3764	Sortase (surface protein transpeptidase)
Sta0113_RS01990	COG1760	l-serine dehydratase
Sta0113_RS01995	COG1760	l-serine dehydratase
Sta0113_RS02005	COG1070	Carbohydrate kinase
Sta0113_RS02030	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Sta0113_RS02045	COG0039	L-malate dehydrogenase activity
Sta0113_RS02050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Sta0113_RS02060	COG1263	PTS System
Sta0113_RS02060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Sta0113_RS02060	COG2190	(PTS) system
Sta0113_RS02065	COG0028	Belongs to the TPP enzyme family
Sta0113_RS02070	COG1346	cytolysis
Sta0113_RS02075	COG1380	Effector of murein hydrolase LrgA
Sta0113_RS02080	COG0583	DNA-binding transcription factor activity
Sta0113_RS02090	COG3942	CHAP domain
Sta0113_RS02090	COG1388	LysM domain
Sta0113_RS02100	COG0183	Belongs to the thiolase family
Sta0113_RS02105	COG3425	synthase
Sta0113_RS02110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Sta0113_RS02140	COG1012	belongs to the aldehyde dehydrogenase family
Sta0113_RS02145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Sta0113_RS02150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Sta0113_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
Sta0113_RS02170	COG2217	Heavy metal translocating P-type atpase
Sta0113_RS02175	COG2608	mercury ion transmembrane transporter activity
Sta0113_RS02185	COG0436	Aminotransferase
Sta0113_RS02195	COG0741	lytic transglycosylase activity
Sta0113_RS02200	COG2326	polyphosphate kinase activity
Sta0113_RS02210	COG1309	transcriptional regulator
Sta0113_RS02215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Sta0113_RS02245	COG3001	Fructosamine kinase
Sta0113_RS02250	COG0167	dihydroorotate dehydrogenase activity
Sta0113_RS02260	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Sta0113_RS02270	COG3527	Alpha-acetolactate decarboxylase
Sta0113_RS02275	COG0028	Belongs to the TPP enzyme family
Sta0113_RS02280	COG0531	amino acid
Sta0113_RS02290	COG1464	Belongs to the NlpA lipoprotein family
Sta0113_RS02310	COG3271	cysteine-type peptidase activity
Sta0113_RS02310	COG2274	protein secretion by the type I secretion system
Sta0113_RS02315	COG3588	fructose-bisphosphate aldolase
Sta0113_RS02320	COG0579	oxidoreductase
Sta0113_RS02325	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Sta0113_RS02330	COG0574	Belongs to the PEP-utilizing enzyme family
Sta0113_RS02330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Sta0113_RS02335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Sta0113_RS02350	COG1473	amidohydrolase
Sta0113_RS02355	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Sta0113_RS02360	COG1012	belongs to the aldehyde dehydrogenase family
Sta0113_RS02365	COG1510	regulation of RNA biosynthetic process
Sta0113_RS02370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Sta0113_RS02380	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Sta0113_RS02390	COG3942	CHAP domain
Sta0113_RS02395	COG0529	Catalyzes the synthesis of activated sulfate
Sta0113_RS02400	COG2046	Belongs to the sulfate adenylyltransferase family
Sta0113_RS02405	COG0730	response to heat
Sta0113_RS02420	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Sta0113_RS02425	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Sta0113_RS02430	COG0175	sulfate reduction
Sta0113_RS02455	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Sta0113_RS02460	COG1028	Short-chain dehydrogenase reductase Sdr
Sta0113_RS02465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Sta0113_RS02480	COG1136	(ABC) transporter
Sta0113_RS02485	COG2205	protein histidine kinase activity
Sta0113_RS02490	COG0745	RESPONSE REGULATOR receiver
Sta0113_RS02505	COG1785	Belongs to the alkaline phosphatase family
Sta0113_RS02515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Sta0113_RS02525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Sta0113_RS02610	COG3961	Belongs to the TPP enzyme family
Sta0113_RS02630	COG2235	arginine
Sta0113_RS02645	COG3682	Transcriptional regulator
Sta0113_RS02680	COG4974	Belongs to the 'phage' integrase family
Sta0113_RS02710	COG1705	Flagellar rod assembly protein muramidase FlgJ
Sta0113_RS02710	COG3942	CHAP domain
Sta0113_RS02715	COG1288	antiporter activity
Sta0113_RS02725	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Sta0113_RS02730	COG0583	DNA-binding transcription factor activity
Sta0113_RS02740	COG2409	Drug exporters of the RND superfamily
Sta0113_RS02745	COG2113	Glycine betaine
Sta0113_RS02755	COG2814	Major facilitator Superfamily
Sta0113_RS02770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Sta0113_RS02785	COG0653	protein targeting
Sta0113_RS02795	COG1073	alpha beta
Sta0113_RS02805	COG0201	protein transport
Sta0113_RS02810	COG3391	amine dehydrogenase activity
Sta0113_RS02835	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Sta0113_RS02850	COG0737	Belongs to the 5'-nucleotidase family
Sta0113_RS02855	COG2814	Major facilitator Superfamily
Sta0113_RS02870	COG1959	2 iron, 2 sulfur cluster binding
Sta0113_RS02875	COG1476	TRANSCRIPTIONal
Sta0113_RS02885	COG1131	(ABC) transporter
Sta0113_RS02905	COG4716	Myosin-crossreactive antigen
Sta0113_RS02915	COG1686	Belongs to the peptidase S11 family
Sta0113_RS02925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Sta0113_RS02930	COG4413	Urea transporter
Sta0113_RS02945	COG0804	urea catabolic process
Sta0113_RS02950	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Sta0113_RS02965	COG0829	nickel cation binding
Sta0113_RS02970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Sta0113_RS02975	COG3386	PFAM SMP-30 Gluconolaconase
Sta0113_RS02980	COG1054	Belongs to the UPF0176 family
Sta0113_RS02990	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
Sta0113_RS02995	COG1028	Short-chain dehydrogenase reductase Sdr
Sta0113_RS03000	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Sta0113_RS03020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Sta0113_RS03025	COG1124	(ABC) transporter
Sta0113_RS03045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Sta0113_RS03050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Sta0113_RS03060	COG1737	Transcriptional regulator
Sta0113_RS03065	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
Sta0113_RS03070	COG0363	glucosamine-6-phosphate deaminase activity
Sta0113_RS03080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Sta0113_RS03105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Sta0113_RS03110	COG0549	Belongs to the carbamate kinase family
Sta0113_RS03115	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Sta0113_RS03145	COG0446	pyridine nucleotide-disulphide oxidoreductase
Sta0113_RS03170	COG1131	(ABC) transporter
Sta0113_RS03175	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Sta0113_RS03185	COG2314	TM2 domain
Sta0113_RS03210	COG1073	alpha beta
Sta0113_RS03215	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Sta0113_RS03220	COG0753	catalase activity
Sta0113_RS03285	COG2962	Rard protein
Sta0113_RS03290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Sta0113_RS03310	COG0508	dehydrogenase complex catalyzes the overall conversion of
Sta0113_RS03315	COG0022	dehydrogenase e1 component
Sta0113_RS03320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Sta0113_RS03325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Sta0113_RS03340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Sta0113_RS03360	COG0583	DNA-binding transcription factor activity
Sta0113_RS03365	COG2855	membrane
Sta0113_RS03385	COG1028	Short-chain dehydrogenase reductase Sdr
Sta0113_RS03390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Sta0113_RS03395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Sta0113_RS03400	COG1846	Transcriptional regulator
Sta0113_RS03410	COG2814	Major facilitator Superfamily
Sta0113_RS03425	COG0583	DNA-binding transcription factor activity
Sta0113_RS03430	COG2814	Major facilitator Superfamily
Sta0113_RS03435	COG1288	antiporter activity
Sta0113_RS03450	COG1876	peptidase activity
Sta0113_RS03460	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Sta0113_RS03465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Sta0113_RS03470	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Sta0113_RS03520	COG0753	catalase activity
Sta0113_RS03520	COG0693	protein deglycase activity
Sta0113_RS03525	COG0778	Nitroreductase
Sta0113_RS03530	COG1113	amino acid transport
Sta0113_RS03535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Sta0113_RS03545	COG1401	restriction endodeoxyribonuclease activity
Sta0113_RS03550	COG1114	Component of the transport system for branched-chain amino acids
Sta0113_RS03565	COG0471	metal ion transport
Sta0113_RS03570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sta0113_RS03580	COG0668	transmembrane transport
Sta0113_RS03585	COG0589	response to stress
Sta0113_RS03600	COG0523	cobalamin synthesis protein
Sta0113_RS03615	COG1278	Cold shock
Sta0113_RS03620	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Sta0113_RS03630	COG1064	alcohol dehydrogenase
Sta0113_RS03645	COG1063	alcohol dehydrogenase
Sta0113_RS03660	COG1131	(ABC) transporter
Sta0113_RS03675	COG1388	LysM domain
Sta0113_RS03680	COG2132	Multicopper oxidase
Sta0113_RS03685	COG2217	Heavy metal translocating P-type atpase
Sta0113_RS03695	COG0640	Transcriptional regulator
Sta0113_RS03715	COG0446	pyridine nucleotide-disulphide oxidoreductase
Sta0113_RS03725	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Sta0113_RS03750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Sta0113_RS03770	COG0431	NADPH-dependent FMN reductase
Sta0113_RS03770	COG1053	succinate dehydrogenase
Sta0113_RS03770	COG3976	FMN-binding domain protein
Sta0113_RS03790	COG0076	glutamate decarboxylase activity
Sta0113_RS03810	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Sta0113_RS03815	COG0732	type I restriction modification DNA specificity domain
Sta0113_RS03820	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Sta0113_RS03835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Sta0113_RS03840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Sta0113_RS03850	COG4863	YycH protein
Sta0113_RS03855	COG5002	protein histidine kinase activity
Sta0113_RS03860	COG0745	RESPONSE REGULATOR receiver
Sta0113_RS03875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Sta0113_RS03880	COG0305	Participates in initiation and elongation during chromosome replication
Sta0113_RS03885	COG0359	binds to the 23S rRNA
Sta0113_RS03890	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Sta0113_RS03900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Sta0113_RS03910	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Sta0113_RS03915	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Sta0113_RS03920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Sta0113_RS03930	COG0187	DNA topoisomerase II activity
Sta0113_RS03935	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Sta0113_RS03940	COG2501	S4 domain
Sta0113_RS03945	COG0592	DNA-directed DNA polymerase activity
Sta0113_RS03950	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Sta0113_RS03960	COG0594	ribonuclease P activity
Sta0113_RS03965	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Sta0113_RS03970	COG0445	tRNA wobble uridine modification
Sta0113_RS03975	COG0357	Ribosomal RNA small subunit methyltransferase G
Sta0113_RS04010	COG0577	efflux transmembrane transporter activity
Sta0113_RS04015	COG1136	(ABC) transporter
Sta0113_RS04035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Sta0113_RS04045	COG2376	Dihydroxyacetone kinase
Sta0113_RS04050	COG1461	Dihydroxyacetone kinase
Sta0113_RS04055	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
Sta0113_RS04090	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Sta0113_RS04095	COG0646	methionine synthase
Sta0113_RS04095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Sta0113_RS04100	COG0626	cystathionine gamma-synthase activity
Sta0113_RS04105	COG0626	cystathionine gamma-synthase activity
Sta0113_RS04110	COG1475	DNA binding
Sta0113_RS04115	COG0668	transmembrane transport
Sta0113_RS04120	COG4481	Protein conserved in bacteria
Sta0113_RS04125	COG0012	GTP binding
Sta0113_RS04135	COG0360	Binds together with S18 to 16S ribosomal RNA
Sta0113_RS04145	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Sta0113_RS04180	COG3634	alkyl hydroperoxide reductase activity
Sta0113_RS04185	COG0450	alkyl hydroperoxide reductase
Sta0113_RS04195	COG0778	Nitroreductase
Sta0113_RS04200	COG1823	symporter activity
Sta0113_RS04220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Sta0113_RS04225	COG2233	PERMEase
Sta0113_RS04230	COG0517	IMP dehydrogenase activity
Sta0113_RS04230	COG0516	GMP reductase activity
Sta0113_RS04235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Sta0113_RS04235	COG0519	Catalyzes the synthesis of GMP from XMP
Sta0113_RS04250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Sta0113_RS04255	COG3002	Belongs to the UPF0753 family
Sta0113_RS04260	COG5609	conserved protein (DUF2294)
Sta0113_RS04265	COG0671	phosphoesterase, PA-phosphatase related
Sta0113_RS04270	COG1647	Serine aminopeptidase, S33
Sta0113_RS04280	COG0733	neurotransmitter:sodium symporter activity
Sta0113_RS04290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Sta0113_RS04295	COG0626	cystathionine gamma-synthase activity
Sta0113_RS04300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Sta0113_RS04305	COG2011	ABC-type metal ion transport system permease component
Sta0113_RS04315	COG3942	CHAP domain
Sta0113_RS04315	COG1388	LysM domain
Sta0113_RS04325	COG0494	nUDIX hydrolase
Sta0113_RS04345	COG0070	glutamate synthase
Sta0113_RS04345	COG0069	glutamate synthase activity
Sta0113_RS04345	COG0067	glutamate synthase
Sta0113_RS04350	COG0493	'glutamate synthase
Sta0113_RS04360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Sta0113_RS04360	COG1263	PTS System
Sta0113_RS04365	COG0366	Alpha amylase catalytic
Sta0113_RS04370	COG2188	Transcriptional regulator
Sta0113_RS04385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Sta0113_RS04395	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Sta0113_RS04415	COG1982	Orn Lys Arg decarboxylase major
Sta0113_RS04420	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Sta0113_RS04425	COG3870	Protein conserved in bacteria
Sta0113_RS04430	COG0470	DNA polymerase III
Sta0113_RS04435	COG1774	PSP1 C-terminal conserved region
Sta0113_RS04440	COG4467	Involved in initiation control of chromosome replication
Sta0113_RS04445	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Sta0113_RS04450	COG2827	Endonuclease containing a URI domain
Sta0113_RS04455	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Sta0113_RS04460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sta0113_RS04460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sta0113_RS04465	COG0084	hydrolase, TatD family'
Sta0113_RS04470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Sta0113_RS04475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Sta0113_RS04480	COG4466	Protein conserved in bacteria
Sta0113_RS04485	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Sta0113_RS04490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Sta0113_RS04495	COG0251	oxidation-reduction process
Sta0113_RS04500	COG2088	sporulation resulting in formation of a cellular spore
Sta0113_RS04505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Sta0113_RS04510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Sta0113_RS04515	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Sta0113_RS04520	COG0193	aminoacyl-tRNA hydrolase activity
Sta0113_RS04525	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Sta0113_RS04530	COG2244	polysaccharide biosynthetic process
Sta0113_RS04535	COG3956	TIGRFAM MazG family protein
Sta0113_RS04540	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Sta0113_RS04550	COG1098	S1 RNA binding domain
Sta0113_RS04565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Sta0113_RS04570	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Sta0113_RS04575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Sta0113_RS04590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Sta0113_RS04595	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Sta0113_RS04680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Sta0113_RS04685	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Sta0113_RS04690	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Sta0113_RS04695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Sta0113_RS04700	COG4463	regulation of RNA biosynthetic process
Sta0113_RS04705	COG3880	PFAM UvrB UvrC protein
Sta0113_RS04710	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Sta0113_RS04715	COG0542	response to heat
Sta0113_RS04720	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Sta0113_RS04725	COG4956	integral membrane protein (PIN domain superfamily)
Sta0113_RS04730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Sta0113_RS04735	COG1045	serine acetyltransferase
Sta0113_RS04740	COG0215	cysteine-tRNA ligase activity
Sta0113_RS04745	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Sta0113_RS04750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Sta0113_RS04755	COG3688	RNA-binding protein containing a PIN domain
Sta0113_RS04765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Sta0113_RS04770	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Sta0113_RS04775	COG0250	Participates in transcription elongation, termination and antitermination
Sta0113_RS04780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Sta0113_RS04785	COG0081	regulation of translation
Sta0113_RS04790	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Sta0113_RS04800	COG2813	Specifically methylates the guanine in position
Sta0113_RS04805	COG0085	RNA polymerase activity
Sta0113_RS04810	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Sta0113_RS04820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Sta0113_RS04830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Sta0113_RS04835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Sta0113_RS04840	COG1473	amidohydrolase
Sta0113_RS04865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Sta0113_RS04870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Sta0113_RS04875	COG0582	viral genome integration into host DNA
Sta0113_RS04995	COG1428	Deoxynucleoside kinase
Sta0113_RS05000	COG1428	Deoxynucleoside kinase
Sta0113_RS05010	COG0561	phosphatase activity
Sta0113_RS05015	COG0431	NADPH-dependent FMN reductase
Sta0113_RS05020	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Sta0113_RS05020	COG4932	domain protein
Sta0113_RS05020	COG3266	domain, Protein
Sta0113_RS05035	COG1469	GTP cyclohydrolase I activity
Sta0113_RS05040	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Sta0113_RS05050	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Sta0113_RS05055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Sta0113_RS05060	COG0318	PFAM AMP-dependent synthetase and ligase
Sta0113_RS05065	COG0183	Belongs to the thiolase family
Sta0113_RS05085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Sta0113_RS05095	COG2363	Small membrane protein
Sta0113_RS05100	COG0531	amino acid
Sta0113_RS05115	COG3253	May function as heme-dependent peroxidase
Sta0113_RS05125	COG0095	Lipoate-protein ligase
Sta0113_RS05145	COG4844	belongs to the
Sta0113_RS05150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Sta0113_RS05160	COG0667	Aldo Keto reductase
Sta0113_RS05165	COG0655	NAD(P)H dehydrogenase (quinone) activity
Sta0113_RS05175	COG1078	dGTPase activity
Sta0113_RS05200	COG0018	arginyl-trna synthetase
Sta0113_RS05210	COG0789	Transcriptional regulator
Sta0113_RS05210	COG4978	Transcriptional regulator
Sta0113_RS05220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Sta0113_RS05225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Sta0113_RS05250	COG0596	Alpha beta hydrolase
Sta0113_RS05285	COG2111	Na H antiporter
Sta0113_RS05285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Sta0113_RS05290	COG2111	Na H antiporter
Sta0113_RS05295	COG1006	Multisubunit Na H antiporter MnhC subunit
Sta0113_RS05300	COG0651	ATP synthesis coupled electron transport
Sta0113_RS05305	COG1863	multisubunit Na H antiporter MnhE subunit
Sta0113_RS05310	COG2212	antiporter activity
Sta0113_RS05315	COG1320	monovalent cation:proton antiporter activity
Sta0113_RS05320	COG0025	NhaP-type Na H and K H
Sta0113_RS05335	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Sta0113_RS05340	COG1134	teichoic acid transport
Sta0113_RS05345	COG1682	transport, permease protein
Sta0113_RS05350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Sta0113_RS05360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Sta0113_RS05365	COG1132	(ABC) transporter
Sta0113_RS05370	COG0463	Glycosyl transferase, family 2
Sta0113_RS05370	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
Sta0113_RS05375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Sta0113_RS05380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Sta0113_RS05385	COG1120	ATPase activity
Sta0113_RS05390	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
Sta0113_RS05400	COG3949	Membrane
Sta0113_RS05410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Sta0113_RS05415	COG0745	RESPONSE REGULATOR receiver
Sta0113_RS05420	COG2205	protein histidine kinase activity
Sta0113_RS05425	COG1136	(ABC) transporter
Sta0113_RS05430	COG0577	efflux transmembrane transporter activity
Sta0113_RS05435	COG1392	Phosphate transport regulator
Sta0113_RS05440	COG0306	phosphate transporter
Sta0113_RS05445	COG1388	LysM domain
Sta0113_RS05445	COG3942	CHAP domain
Sta0113_RS05455	COG2207	Transcriptional regulator
Sta0113_RS05455	COG0662	Cupin 2, conserved barrel domain protein
Sta0113_RS05465	COG0217	transcriptional regulatory protein
Sta0113_RS05475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Sta0113_RS05485	COG0583	DNA-binding transcription factor activity
Sta0113_RS05520	COG1611	Belongs to the LOG family
Sta0113_RS05525	COG1671	Belongs to the UPF0178 family
Sta0113_RS05535	COG1968	undecaprenyl-diphosphatase activity
Sta0113_RS05540	COG4988	ABC transporter
Sta0113_RS05545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Sta0113_RS05555	COG0523	cobalamin synthesis protein
Sta0113_RS05565	COG0415	Belongs to the DNA photolyase family
Sta0113_RS05585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Sta0113_RS05590	COG1349	DNA-binding transcription factor activity
Sta0113_RS05595	COG1105	Belongs to the carbohydrate kinase PfkB family
Sta0113_RS05600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Sta0113_RS05600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Sta0113_RS05600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Sta0113_RS05605	COG1253	flavin adenine dinucleotide binding
Sta0113_RS05610	COG0656	L-ascorbic acid biosynthetic process
Sta0113_RS05615	COG0463	Glycosyl transferase, family 2
Sta0113_RS05625	COG0602	queuosine metabolic process
Sta0113_RS05630	COG0720	synthase
Sta0113_RS05635	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Sta0113_RS05640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Sta0113_RS05640	COG0512	Glutamine amidotransferase of anthranilate synthase
Sta0113_RS05645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Sta0113_RS05670	COG1368	sulfuric ester hydrolase activity
Sta0113_RS05680	COG0488	(ABC) transporter
Sta0113_RS05685	COG0514	ATP-dependent DNA helicase (RecQ)
Sta0113_RS05690	COG0517	IMP dehydrogenase activity
Sta0113_RS05690	COG1125	glycine betaine transport
Sta0113_RS05695	COG1174	glycine betaine transport
Sta0113_RS05705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Sta0113_RS05715	COG1597	lipid kinase activity
Sta0113_RS05720	COG3104	oligopeptide transport
Sta0113_RS05725	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Sta0113_RS05735	COG1780	Probably involved in ribonucleotide reductase function
Sta0113_RS05740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Sta0113_RS05745	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Sta0113_RS05750	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Sta0113_RS05755	COG4605	iron ion homeostasis
Sta0113_RS05760	COG4604	ABC transporter, ATP-binding protein
Sta0113_RS05765	COG4607	ABC-type enterochelin transport system periplasmic component
Sta0113_RS05775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Sta0113_RS05790	COG3118	belongs to the thioredoxin family
Sta0113_RS05795	COG1929	Belongs to the glycerate kinase type-1 family
Sta0113_RS05800	COG2195	Cleaves the N-terminal amino acid of tripeptides
Sta0113_RS05815	COG2199	diguanylate cyclase activity
Sta0113_RS05820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Sta0113_RS05825	COG1739	Uncharacterized protein family UPF0029
Sta0113_RS05835	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
Sta0113_RS05840	COG1040	competence protein
Sta0113_RS05845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Sta0113_RS05850	COG0653	protein targeting
Sta0113_RS05860	COG3942	CHAP domain
Sta0113_RS05860	COG1388	LysM domain
Sta0113_RS05875	COG0556	nucleotide-excision repair
Sta0113_RS05880	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Sta0113_RS05885	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Sta0113_RS05890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Sta0113_RS05895	COG0110	maltose O-acetyltransferase activity
Sta0113_RS05905	COG0492	ferredoxin-NADP+ reductase activity
Sta0113_RS05910	COG1660	Displays ATPase and GTPase activities
Sta0113_RS05915	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Sta0113_RS05920	COG1481	regulation of sporulation
Sta0113_RS05930	COG0740	serine-type endopeptidase activity
Sta0113_RS05940	COG1090	epimerase
Sta0113_RS05960	COG2390	Transcriptional regulator
Sta0113_RS05965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Sta0113_RS05970	COG0126	phosphoglycerate kinase activity
Sta0113_RS05975	COG0149	triose-phosphate isomerase activity
Sta0113_RS05980	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Sta0113_RS05985	COG0148	phosphopyruvate hydratase activity
Sta0113_RS05995	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Sta0113_RS06000	COG1647	Serine aminopeptidase, S33
Sta0113_RS06005	COG0557	exoribonuclease II activity
Sta0113_RS06010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Sta0113_RS06060	COG4195	phage-related replication protein
Sta0113_RS06090	COG0406	alpha-ribazole phosphatase activity
Sta0113_RS06100	COG1764	response to oxidative stress
Sta0113_RS06105	COG0710	3-dehydroquinate dehydratase activity
Sta0113_RS06115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Sta0113_RS06120	COG1393	Belongs to the ArsC family
Sta0113_RS06125	COG0509	glycine decarboxylation via glycine cleavage system
Sta0113_RS06130	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Sta0113_RS06140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Sta0113_RS06145	COG2011	ABC-type metal ion transport system permease component
Sta0113_RS06150	COG1464	Belongs to the NlpA lipoprotein family
Sta0113_RS06160	COG3237	CsbD-like
Sta0113_RS06170	COG0396	ATPase activity
Sta0113_RS06175	COG0719	Fe-S assembly protein
Sta0113_RS06180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Sta0113_RS06185	COG0822	iron-sulfur transferase activity
Sta0113_RS06190	COG0719	Fe-S assembly protein
Sta0113_RS06200	COG1801	Protein of unknown function DUF72
Sta0113_RS06205	COG0730	response to heat
Sta0113_RS06210	COG0737	Belongs to the 5'-nucleotidase family
Sta0113_RS06215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Sta0113_RS06220	COG4470	Protein conserved in bacteria
Sta0113_RS06230	COG2445	Protein of unknown function DUF86
Sta0113_RS06235	COG0647	UMP catabolic process
Sta0113_RS06245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Sta0113_RS06250	COG1696	Membrane protein involved in D-alanine export
Sta0113_RS06255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Sta0113_RS06260	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
Sta0113_RS06265	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Sta0113_RS06270	COG4837	Protein of unknown function (DUF1462)
Sta0113_RS06275	COG1252	NADH dehydrogenase
Sta0113_RS06280	COG4844	belongs to the
Sta0113_RS06285	COG0316	Belongs to the HesB IscA family
Sta0113_RS06290	COG1252	NADH dehydrogenase
Sta0113_RS06295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Sta0113_RS06300	COG2056	Na+-H+ antiporter family
Sta0113_RS06305	COG2050	protein possibly involved in aromatic compounds catabolism
Sta0113_RS06315	COG1320	monovalent cation:proton antiporter activity
Sta0113_RS06320	COG2212	antiporter activity
Sta0113_RS06325	COG1863	multisubunit Na H antiporter MnhE subunit
Sta0113_RS06330	COG0651	ATP synthesis coupled electron transport
Sta0113_RS06335	COG1006	Multisubunit Na H antiporter MnhC subunit
Sta0113_RS06340	COG2111	Na H antiporter
Sta0113_RS06345	COG2111	Na H antiporter
Sta0113_RS06345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Sta0113_RS06355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Sta0113_RS06360	COG1098	S1 RNA binding domain
Sta0113_RS06365	COG1902	pentaerythritol trinitrate reductase activity
Sta0113_RS06370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Sta0113_RS06390	COG0165	Argininosuccinate lyase
Sta0113_RS06395	COG0137	argininosuccinate synthase activity
Sta0113_RS06400	COG0166	Belongs to the GPI family
Sta0113_RS06405	COG0398	Pfam SNARE associated Golgi protein
Sta0113_RS06420	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Sta0113_RS06425	COG1074	ATP-dependent DNA helicase activity
Sta0113_RS06430	COG0179	Fumarylacetoacetate (FAA) hydrolase
Sta0113_RS06440	COG0446	pyridine nucleotide-disulphide oxidoreductase
Sta0113_RS06445	COG0561	phosphatase activity
Sta0113_RS06460	COG0542	response to heat
Sta0113_RS06470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Sta0113_RS06485	COG0601	transmembrane transport
Sta0113_RS06490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Sta0113_RS06495	COG0444	Belongs to the ABC transporter superfamily
Sta0113_RS06500	COG4608	Belongs to the ABC transporter superfamily
Sta0113_RS06505	COG4166	transmembrane transport
Sta0113_RS06515	COG0444	Belongs to the ABC transporter superfamily
Sta0113_RS06520	COG4608	Belongs to the ABC transporter superfamily
Sta0113_RS06525	COG0601	transmembrane transport
Sta0113_RS06530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Sta0113_RS06535	COG0180	Tryptophanyl-tRNA synthetase
Sta0113_RS06540	COG1393	Belongs to the ArsC family
Sta0113_RS06545	COG4862	establishment of competence for transformation
Sta0113_RS06555	COG1164	Oligoendopeptidase f
Sta0113_RS06560	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Sta0113_RS06565	COG2346	COG2346, Truncated hemoglobins
Sta0113_RS06580	COG2357	RelA SpoT domain protein
Sta0113_RS06585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Sta0113_RS06590	COG0564	pseudouridine synthase activity
Sta0113_RS06595	COG2239	Acts as a magnesium transporter
Sta0113_RS06600	COG0475	glutathione-regulated potassium exporter activity
Sta0113_RS06600	COG0569	domain protein
Sta0113_RS06615	COG0628	permease
Sta0113_RS06620	COG2382	esterase
Sta0113_RS06625	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Sta0113_RS06630	COG2814	Major facilitator Superfamily
Sta0113_RS06635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Sta0113_RS06640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Sta0113_RS06650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Sta0113_RS06655	COG0861	Integral membrane protein TerC family
Sta0113_RS06660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Sta0113_RS06660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Sta0113_RS06665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Sta0113_RS06675	COG4873	Protein conserved in bacteria
Sta0113_RS06840	COG1575	Belongs to the MenA family. Type 1 subfamily
Sta0113_RS06845	COG1169	isochorismate synthase
Sta0113_RS06850	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Sta0113_RS06860	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Sta0113_RS06865	COG0436	Aminotransferase
Sta0113_RS06875	COG4193	domain, Protein
Sta0113_RS06875	COG5632	N-Acetylmuramoyl-L-alanine amidase
Sta0113_RS06875	COG3266	domain, Protein
Sta0113_RS06890	COG1316	TRANSCRIPTIONal
Sta0113_RS06905	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Sta0113_RS06910	COG1845	cytochrome c oxidase, subunit III
Sta0113_RS06915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Sta0113_RS06920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Sta0113_RS06930	COG1017	nitric oxide dioxygenase activity
Sta0113_RS06930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Sta0113_RS06940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Sta0113_RS06945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Sta0113_RS06950	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Sta0113_RS06955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Sta0113_RS06960	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Sta0113_RS06965	COG0047	phosphoribosylformylglycinamidine synthase activity
Sta0113_RS06970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Sta0113_RS06980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Sta0113_RS06990	COG0138	bifunctional purine biosynthesis protein purh
Sta0113_RS06995	COG0151	Belongs to the GarS family
Sta0113_RS07005	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Sta0113_RS07010	COG4172	Belongs to the ABC transporter superfamily
Sta0113_RS07030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Sta0113_RS07045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Sta0113_RS07055	COG1271	oxidase subunit
Sta0113_RS07060	COG1294	oxidase, subunit
Sta0113_RS07065	COG0569	domain protein
Sta0113_RS07070	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Sta0113_RS07075	COG5503	Protein of unknown function (DUF1447)
Sta0113_RS07080	COG0242	peptide deformylase activity
Sta0113_RS07100	COG0508	dehydrogenase complex catalyzes the overall conversion of
Sta0113_RS07110	COG4476	Belongs to the UPF0223 family
Sta0113_RS07115	COG3800	Transcriptional regulator
Sta0113_RS07115	COG1396	sequence-specific DNA binding
Sta0113_RS07120	COG3842	ATPase activity
Sta0113_RS07125	COG1176	ABC-type spermidine putrescine transport system, permease component I
Sta0113_RS07130	COG1177	transmembrane transport
Sta0113_RS07135	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Sta0113_RS07145	COG1914	H( )-stimulated, divalent metal cation uptake system
Sta0113_RS07150	COG4493	Belongs to the UPF0637 family
Sta0113_RS07155	COG0456	acetyltransferase
Sta0113_RS07160	COG0483	inositol monophosphate 1-phosphatase activity
Sta0113_RS07170	COG1217	gtp-binding protein TYPA
Sta0113_RS07180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Sta0113_RS07185	COG4838	Belongs to the UPF0358 family
Sta0113_RS07190	COG0772	Belongs to the SEDS family
Sta0113_RS07200	COG1612	heme a metabolic process
Sta0113_RS07205	COG0109	protoheme IX farnesyltransferase activity
Sta0113_RS07220	COG3679	Belongs to the UPF0342 family
Sta0113_RS07225	COG0584	glycerophosphoryl diester phosphodiesterase
Sta0113_RS07240	COG0742	ribosomal rna small subunit methyltransferase
Sta0113_RS07245	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Sta0113_RS07250	COG1323	Belongs to the UPF0348 family
Sta0113_RS07260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Sta0113_RS07265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Sta0113_RS07270	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Sta0113_RS07275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sta0113_RS07275	COG0072	phenylalanine-tRNA ligase activity
Sta0113_RS07280	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Sta0113_RS07295	COG1796	DNA polymerase
Sta0113_RS07295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Sta0113_RS07300	COG1193	negative regulation of DNA recombination
Sta0113_RS07305	COG3118	belongs to the thioredoxin family
Sta0113_RS07310	COG0322	excinuclease ABC activity
Sta0113_RS07315	COG2009	succinate dehydrogenase
Sta0113_RS07320	COG1053	succinate dehydrogenase
Sta0113_RS07325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Sta0113_RS07330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Sta0113_RS07335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Sta0113_RS07380	COG1011	Hydrolase
Sta0113_RS07385	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
Sta0113_RS07390	COG2001	Belongs to the MraZ family
Sta0113_RS07395	COG0275	rRNA processing
Sta0113_RS07400	COG4839	cell division protein FtsL
Sta0113_RS07405	COG0768	penicillin binding
Sta0113_RS07410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Sta0113_RS07415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Sta0113_RS07420	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Sta0113_RS07425	COG0849	cell division
Sta0113_RS07430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Sta0113_RS07435	COG1496	oxidoreductase activity
Sta0113_RS07440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Sta0113_RS07445	COG1799	cell septum assembly
Sta0113_RS07450	COG0762	integral membrane protein
Sta0113_RS07460	COG3599	regulation of cell shape
Sta0113_RS07465	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Sta0113_RS07470	COG0702	epimerase
Sta0113_RS07480	COG3942	CHAP domain
Sta0113_RS07485	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Sta0113_RS07490	COG0564	pseudouridine synthase activity
Sta0113_RS07495	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Sta0113_RS07500	COG2233	PERMEase
Sta0113_RS07505	COG0540	Belongs to the ATCase OTCase family
Sta0113_RS07515	COG0505	Belongs to the CarA family
Sta0113_RS07520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Sta0113_RS07525	COG0284	orotidine-5'-phosphate decarboxylase activity
Sta0113_RS07530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Sta0113_RS07545	COG1293	RNA-binding protein homologous to eukaryotic snRNP
Sta0113_RS07550	COG0194	GDP metabolic process
Sta0113_RS07555	COG1758	RNA polymerase activity
Sta0113_RS07560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Sta0113_RS07565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Sta0113_RS07570	COG2314	TM2 domain
Sta0113_RS07580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Sta0113_RS07585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Sta0113_RS07585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Sta0113_RS07590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Sta0113_RS07595	COG0631	protein serine/threonine phosphatase activity
Sta0113_RS07605	COG1162	GTPase activity
Sta0113_RS07610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Sta0113_RS07615	COG1564	THIamine pyrophosphokinase
Sta0113_RS07620	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Sta0113_RS07625	COG1302	Protein conserved in bacteria
Sta0113_RS07630	COG1461	Dihydroxyacetone kinase
Sta0113_RS07635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Sta0113_RS07640	COG1349	DNA-binding transcription factor activity
Sta0113_RS07645	COG0416	fatty acid biosynthetic process
Sta0113_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
Sta0113_RS07660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Sta0113_RS07665	COG0571	ribonuclease III activity
Sta0113_RS07670	COG1196	nuclear chromosome segregation
Sta0113_RS07675	COG0552	protein localization to endoplasmic reticulum
Sta0113_RS07680	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
Sta0113_RS07685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Sta0113_RS07695	COG0228	four-way junction DNA binding
Sta0113_RS07700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Sta0113_RS07705	COG0336	Belongs to the RNA methyltransferase TrmD family
Sta0113_RS07710	COG0335	large ribosomal subunit rRNA binding
Sta0113_RS07725	COG4485	Bacterial membrane protein, YfhO
Sta0113_RS07735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Sta0113_RS07740	COG0045	succinate-CoA ligase (ADP-forming) activity
Sta0113_RS07745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Sta0113_RS07750	COG0758	DNA mediated transformation
Sta0113_RS07755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Sta0113_RS07760	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Sta0113_RS07765	COG4974	Belongs to the 'phage' integrase family
Sta0113_RS07770	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Sta0113_RS07775	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Sta0113_RS07780	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Sta0113_RS07785	COG0052	Belongs to the universal ribosomal protein uS2 family
Sta0113_RS07790	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Sta0113_RS07795	COG0528	UMP kinase activity
Sta0113_RS07800	COG0233	cytoplasmic translational termination
Sta0113_RS07805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Sta0113_RS07810	COG4589	Belongs to the CDS family
Sta0113_RS07820	COG0442	prolyl-tRNA aminoacylation
Sta0113_RS07825	COG2176	DNA-directed DNA polymerase activity
Sta0113_RS07830	COG0779	Required for maturation of 30S ribosomal subunits
Sta0113_RS07835	COG0195	Participates in both transcription termination and antitermination
Sta0113_RS07840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Sta0113_RS07850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Sta0113_RS07855	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Sta0113_RS07860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Sta0113_RS07865	COG0196	riboflavin kinase activity
Sta0113_RS07870	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Sta0113_RS07875	COG1185	polyribonucleotide nucleotidyltransferase activity
Sta0113_RS07880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Sta0113_RS07885	COG1674	ftsk spoiiie
Sta0113_RS07890	COG2188	Transcriptional regulator
Sta0113_RS07895	COG0612	Peptidase, M16
Sta0113_RS07900	COG0612	Peptidase, M16
Sta0113_RS07905	COG0300	oxidoreductase activity
Sta0113_RS07925	COG1546	Belongs to the CinA family
Sta0113_RS07925	COG1058	Belongs to the CinA family
Sta0113_RS07930	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Sta0113_RS07935	COG1418	mRNA catabolic process
Sta0113_RS07945	COG1692	metallophosphoesterase
Sta0113_RS07950	COG0674	pyruvate-flavodoxin oxidoreductase activity
Sta0113_RS07950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Sta0113_RS07955	COG1013	pyruvate-flavodoxin oxidoreductase activity
Sta0113_RS07960	COG4195	phage-related replication protein
Sta0113_RS07970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Sta0113_RS07985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Sta0113_RS07990	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Sta0113_RS07995	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Sta0113_RS08000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Sta0113_RS08005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Sta0113_RS08010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Sta0113_RS08015	COG2267	carboxylic ester hydrolase activity
Sta0113_RS08020	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Sta0113_RS08025	COG1923	regulation of RNA biosynthetic process
Sta0113_RS08030	COG0386	Belongs to the glutathione peroxidase family
Sta0113_RS08035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Sta0113_RS08040	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Sta0113_RS08050	COG0789	Transcriptional regulator
Sta0113_RS08070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Sta0113_RS08075	COG1131	(ABC) transporter
Sta0113_RS08085	COG4585	Histidine kinase
Sta0113_RS08090	COG2197	response regulator
Sta0113_RS08115	COG0527	aspartate kinase activity
Sta0113_RS08120	COG0460	homoserine dehydrogenase
Sta0113_RS08125	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Sta0113_RS08130	COG0083	homoserine kinase activity
Sta0113_RS08145	COG0833	amino acid
Sta0113_RS08155	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Sta0113_RS08170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Sta0113_RS08175	COG4224	UPF0291 protein
Sta0113_RS08185	COG3763	UPF0154 protein
Sta0113_RS08190	COG4846	Membrane protein involved in cytochrome C biogenesis
Sta0113_RS08195	COG0420	3'-5' exonuclease activity
Sta0113_RS08200	COG0419	ATPase involved in DNA repair
Sta0113_RS08205	COG1970	mechanosensitive ion channel activity
Sta0113_RS08210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Sta0113_RS08220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Sta0113_RS08225	COG0824	Thioesterase
Sta0113_RS08230	COG4841	protein insertion into membrane
Sta0113_RS08235	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Sta0113_RS08240	COG0187	DNA topoisomerase II activity
Sta0113_RS08245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Sta0113_RS08250	COG1115	amino acid carrier protein
Sta0113_RS08255	COG3711	transcriptional antiterminator
Sta0113_RS08260	COG0628	permease
Sta0113_RS08265	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Sta0113_RS08265	COG0392	lysyltransferase activity
Sta0113_RS08280	COG1942	4-Oxalocrotonate Tautomerase
Sta0113_RS08285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Sta0113_RS08290	COG0287	Prephenate dehydrogenase
Sta0113_RS08295	COG1363	Peptidase, m42
Sta0113_RS08300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Sta0113_RS08305	COG0512	Glutamine amidotransferase of anthranilate synthase
Sta0113_RS08310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Sta0113_RS08315	COG0134	indole-3-glycerol-phosphate synthase activity
Sta0113_RS08320	COG0135	phosphoribosylanthranilate isomerase activity
Sta0113_RS08330	COG0159	tryptophan synthase activity
Sta0113_RS08335	COG2348	transferase activity, transferring amino-acyl groups
Sta0113_RS08345	COG4607	ABC-type enterochelin transport system periplasmic component
Sta0113_RS08360	COG0704	Plays a role in the regulation of phosphate uptake
Sta0113_RS08365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Sta0113_RS08370	COG0581	inorganic phosphate transmembrane transporter activity
Sta0113_RS08375	COG0573	inorganic phosphate transmembrane transporter activity
Sta0113_RS08380	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Sta0113_RS08385	COG2996	Protein conserved in bacteria
Sta0113_RS08390	COG0488	(ABC) transporter
Sta0113_RS08395	COG0527	aspartate kinase activity
Sta0113_RS08400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Sta0113_RS08405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Sta0113_RS08410	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Sta0113_RS08415	COG2171	N-acyltransferase activity
Sta0113_RS08420	COG1473	amidohydrolase
Sta0113_RS08440	COG1278	Cold shock
Sta0113_RS08450	COG1254	Belongs to the acylphosphatase family
Sta0113_RS08460	COG3853	Toxic anion resistance protein (TelA)
Sta0113_RS08465	COG1114	Component of the transport system for branched-chain amino acids
Sta0113_RS08470	COG4548	von Willebrand factor, type A
Sta0113_RS08475	COG0714	Associated with various cellular activities
Sta0113_RS08500	COG0567	Dehydrogenase, E1 component
Sta0113_RS08510	COG5002	protein histidine kinase activity
Sta0113_RS08515	COG0745	RESPONSE REGULATOR receiver
Sta0113_RS08520	COG0671	phosphoesterase, PA-phosphatase related
Sta0113_RS08525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Sta0113_RS08535	COG0793	Belongs to the peptidase S41A family
Sta0113_RS08540	COG4479	Belongs to the UPF0346 family
Sta0113_RS08545	COG2190	(PTS) system
Sta0113_RS08550	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Sta0113_RS08580	COG1413	lyase activity
Sta0113_RS08585	COG1413	lyase activity
Sta0113_RS08595	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Sta0113_RS08600	COG0328	RNA-DNA hybrid ribonuclease activity
Sta0113_RS08605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Sta0113_RS08610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Sta0113_RS08620	COG0116	Belongs to the methyltransferase superfamily
Sta0113_RS08630	COG3599	regulation of cell shape
Sta0113_RS08635	COG4474	Belongs to the UPF0398 family
Sta0113_RS08645	COG3331	DNA recombination
Sta0113_RS08650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Sta0113_RS08650	COG4499	WXG100 protein secretion system (Wss), protein YukC
Sta0113_RS08660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Sta0113_RS08665	COG3935	DnaD domain protein
Sta0113_RS08670	COG0017	Asparaginyl-tRNA synthetase
Sta0113_RS08675	COG1199	ATP-dependent helicase activity
Sta0113_RS08675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Sta0113_RS08685	COG0617	tRNA 3'-terminal CCA addition
Sta0113_RS08690	COG0438	transferase activity, transferring glycosyl groups
Sta0113_RS08695	COG1694	Mazg nucleotide pyrophosphohydrolase
Sta0113_RS08700	COG2738	Putative neutral zinc metallopeptidase
Sta0113_RS08705	COG4347	Protein of unknown function (DUF1405)
Sta0113_RS08710	COG5582	Belongs to the UPF0302 family
Sta0113_RS08715	COG0457	Tetratricopeptide repeat
Sta0113_RS08720	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Sta0113_RS08725	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Sta0113_RS08730	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Sta0113_RS08735	COG0105	UTP biosynthetic process
Sta0113_RS08740	COG0142	geranyltranstransferase activity
Sta0113_RS08745	COG2226	methyltransferase
Sta0113_RS08760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Sta0113_RS08765	COG1160	GTP binding
Sta0113_RS08770	COG0539	negative regulation of cytoplasmic translation
Sta0113_RS08775	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Sta0113_RS08785	COG0492	ferredoxin-NADP+ reductase activity
Sta0113_RS08790	COG1388	LysM domain
Sta0113_RS08790	COG1388	LysM domain
Sta0113_RS08795	COG0514	ATP-dependent DNA helicase (RecQ)
Sta0113_RS08805	COG1141	Ferredoxin
Sta0113_RS08815	COG5002	protein histidine kinase activity
Sta0113_RS08820	COG0745	RESPONSE REGULATOR receiver
Sta0113_RS08825	COG1187	pseudouridine synthase activity
Sta0113_RS08830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Sta0113_RS08835	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Sta0113_RS08845	COG4974	Belongs to the 'phage' integrase family
Sta0113_RS08850	COG0735	belongs to the Fur family
Sta0113_RS08855	COG0494	nUDIX hydrolase
Sta0113_RS08860	COG0667	Aldo Keto reductase
Sta0113_RS08865	COG1028	Short-chain dehydrogenase reductase Sdr
Sta0113_RS08870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Sta0113_RS08875	COG1234	tRNA 3'-trailer cleavage
Sta0113_RS08880	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Sta0113_RS08890	COG0366	Alpha amylase catalytic
Sta0113_RS08900	COG2195	Cleaves the N-terminal amino acid of tripeptides
Sta0113_RS08910	COG4129	membrane
Sta0113_RS08920	COG0508	dehydrogenase complex catalyzes the overall conversion of
Sta0113_RS08925	COG0022	dehydrogenase e1 component
Sta0113_RS08930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Sta0113_RS08935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Sta0113_RS08940	COG0497	DNA recombination
Sta0113_RS08945	COG1438	arginine binding
Sta0113_RS08950	COG0142	geranyltranstransferase activity
Sta0113_RS08960	COG1570	exodeoxyribonuclease VII activity
Sta0113_RS08965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Sta0113_RS08970	COG1302	Protein conserved in bacteria
Sta0113_RS08975	COG0439	Biotin carboxylase
Sta0113_RS08980	COG0511	ligase activity, forming carbon-carbon bonds
Sta0113_RS08985	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Sta0113_RS08990	COG0006	proline dipeptidase activity
Sta0113_RS09005	COG0095	Lipoate-protein ligase
Sta0113_RS09010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Sta0113_RS09015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Sta0113_RS09020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Sta0113_RS09025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Sta0113_RS09030	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Sta0113_RS09045	COG4537	Required for transformation and DNA binding
Sta0113_RS09050	COG1459	type II secretion system
Sta0113_RS09055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Sta0113_RS09060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Sta0113_RS09065	COG0011	TIGRFAM Protein of
Sta0113_RS09070	COG1940	carbohydrate kinase activity
Sta0113_RS09075	COG4483	Protein conserved in bacteria
Sta0113_RS09085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Sta0113_RS09095	COG0768	penicillin binding
Sta0113_RS09100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Sta0113_RS09110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Sta0113_RS09115	COG1121	(ABC) transporter
Sta0113_RS09120	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Sta0113_RS09125	COG0513	Belongs to the DEAD box helicase family
Sta0113_RS09130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Sta0113_RS09135	COG2384	SAM-dependent methyltransferase
Sta0113_RS09140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Sta0113_RS09145	COG0358	DNA primase activity
Sta0113_RS09150	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Sta0113_RS09155	COG0517	IMP dehydrogenase activity
Sta0113_RS09160	COG0423	glycine-tRNA ligase activity
Sta0113_RS09165	COG1381	Involved in DNA repair and RecF pathway recombination
Sta0113_RS09170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Sta0113_RS09175	COG0295	cytidine deaminase activity
Sta0113_RS09180	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Sta0113_RS09190	COG1702	phosphate starvation-inducible protein PhoH
Sta0113_RS09200	COG4864	UPF0365 protein
Sta0113_RS09205	COG1030	water channel activity
Sta0113_RS09215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Sta0113_RS09220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Sta0113_RS09225	COG2264	protein methyltransferase activity
Sta0113_RS09230	COG0484	heat shock protein binding
Sta0113_RS09235	COG0443	Heat shock 70 kDa protein
Sta0113_RS09240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Sta0113_RS09245	COG1420	regulation of RNA biosynthetic process
Sta0113_RS09250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Sta0113_RS09255	COG0481	GTPase activity
Sta0113_RS09260	COG0268	Binds directly to 16S ribosomal RNA
Sta0113_RS09265	COG1466	dna polymerase III delta subunit
Sta0113_RS09270	COG0658	competence protein
Sta0113_RS09270	COG2333	competence protein COMEC
Sta0113_RS09275	COG2131	deaminase
Sta0113_RS09280	COG0322	excinuclease ABC activity
Sta0113_RS09285	COG2226	methyltransferase
Sta0113_RS09290	COG0799	negative regulation of ribosome biogenesis
Sta0113_RS09295	COG1713	HD superfamily hydrolase involved in NAD metabolism
Sta0113_RS09300	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Sta0113_RS09305	COG1534	Rna-binding protein
Sta0113_RS09310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Sta0113_RS09315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Sta0113_RS09320	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Sta0113_RS09325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Sta0113_RS09330	COG1914	H( )-stimulated, divalent metal cation uptake system
Sta0113_RS09335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Sta0113_RS09340	COG0439	Biotin carboxylase
Sta0113_RS09350	COG1984	allophanate hydrolase subunit 2
Sta0113_RS09355	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Sta0113_RS09360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Sta0113_RS09365	COG0572	uridine kinase
Sta0113_RS09370	COG0826	peptidase U32
Sta0113_RS09375	COG0826	peptidase U32
Sta0113_RS09385	COG3906	Belongs to the UPF0473 family
Sta0113_RS09390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Sta0113_RS09395	COG4472	Bacterial protein of unknown function (DUF965)
Sta0113_RS09400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Sta0113_RS09405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Sta0113_RS09415	COG0482	sulfurtransferase activity
Sta0113_RS09420	COG1104	cysteine desulfurase activity
Sta0113_RS09425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Sta0113_RS09435	COG1959	2 iron, 2 sulfur cluster binding
Sta0113_RS09440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Sta0113_RS09445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Sta0113_RS09455	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Sta0113_RS09460	COG0124	histidyl-tRNA synthetase
Sta0113_RS09465	COG0860	N-Acetylmuramoyl-L-alanine amidase
Sta0113_RS09470	COG1490	D-aminoacyl-tRNA deacylase activity
Sta0113_RS09475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Sta0113_RS09480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Sta0113_RS09485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Sta0113_RS09485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Sta0113_RS09490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Sta0113_RS09490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Sta0113_RS09495	COG1862	Preprotein translocase
Sta0113_RS09505	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Sta0113_RS09510	COG2255	four-way junction helicase activity
Sta0113_RS09515	COG0632	four-way junction helicase activity
Sta0113_RS09520	COG4492	Belongs to the UPF0735 family
Sta0113_RS09525	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Sta0113_RS09530	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Sta0113_RS09535	COG2868	ribosomal protein
Sta0113_RS09540	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Sta0113_RS09550	COG1792	Involved in formation and maintenance of cell shape
Sta0113_RS09570	COG2003	Belongs to the UPF0758 family
Sta0113_RS09580	COG0285	dihydrofolate synthase activity
Sta0113_RS09585	COG0525	valine-tRNA ligase activity
Sta0113_RS09590	COG2818	Glycosylase
Sta0113_RS09600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Sta0113_RS09615	COG0181	hydroxymethylbilane synthase activity
Sta0113_RS09620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Sta0113_RS09625	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Sta0113_RS09630	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Sta0113_RS09635	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Sta0113_RS09640	COG0544	peptidyl-prolyl cis-trans isomerase activity
Sta0113_RS09650	COG4112	unkown
Sta0113_RS09655	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Sta0113_RS09660	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Sta0113_RS09665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Sta0113_RS09670	COG0833	amino acid
Sta0113_RS09675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Sta0113_RS09680	COG1484	DNA-dependent DNA replication
Sta0113_RS09685	COG3611	Membrane attachment protein
Sta0113_RS09690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Sta0113_RS09700	COG0237	dephospho-CoA kinase activity
Sta0113_RS09705	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Sta0113_RS09710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Sta0113_RS09710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Sta0113_RS09715	COG5002	protein histidine kinase activity
Sta0113_RS09720	COG0745	RESPONSE REGULATOR receiver
Sta0113_RS09725	COG0538	isocitrate dehydrogenase activity
Sta0113_RS09730	COG0372	Belongs to the citrate synthase family
Sta0113_RS09735	COG1113	amino acid transport
Sta0113_RS09740	COG0469	pyruvate kinase activity
Sta0113_RS09745	COG0205	6-phosphofructokinase activity
Sta0113_RS09750	COG0825	malonyl-CoA metabolic process
Sta0113_RS09755	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Sta0113_RS09760	COG0281	malic enzyme
Sta0113_RS09765	COG0587	DNA-directed DNA polymerase activity
Sta0113_RS09770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Sta0113_RS09775	COG4109	DRTGG domain
Sta0113_RS09785	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Sta0113_RS09790	COG0006	proline dipeptidase activity
Sta0113_RS09795	COG0686	Belongs to the AlaDH PNT family
Sta0113_RS09800	COG0589	response to stress
Sta0113_RS09805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Sta0113_RS09810	COG0827	DNA restriction-modification system
Sta0113_RS09815	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Sta0113_RS09825	COG0301	tRNA thio-modification
Sta0113_RS09835	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
Sta0113_RS09840	COG1956	GAF domain-containing protein
Sta0113_RS09845	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Sta0113_RS09850	COG0584	glycerophosphoryl diester phosphodiesterase
Sta0113_RS09855	COG1764	response to oxidative stress
Sta0113_RS09865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Sta0113_RS09875	COG1263	PTS System
Sta0113_RS09875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Sta0113_RS09880	COG0204	Acyl-transferase
Sta0113_RS09885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Sta0113_RS09890	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Sta0113_RS09900	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Sta0113_RS09905	COG1609	Transcriptional regulator
Sta0113_RS09910	COG1605	Chorismate mutase
Sta0113_RS09910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Sta0113_RS09920	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
Sta0113_RS09925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Sta0113_RS09930	COG1674	ftsk spoiiie
Sta0113_RS09935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Sta0113_RS09940	COG4848	Belongs to the UPF0354 family
Sta0113_RS09945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Sta0113_RS09950	COG1363	Peptidase, m42
Sta0113_RS09960	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Sta0113_RS09965	COG0510	thiamine kinase activity
Sta0113_RS09975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Sta0113_RS09985	COG1187	pseudouridine synthase activity
Sta0113_RS09990	COG2244	polysaccharide biosynthetic process
Sta0113_RS09995	COG2081	HI0933 family
Sta0113_RS10005	COG1054	Belongs to the UPF0176 family
Sta0113_RS10010	COG0495	leucyl-tRNA aminoacylation
Sta0113_RS10015	COG2814	Major facilitator Superfamily
Sta0113_RS10020	COG1242	4 iron, 4 sulfur cluster binding
Sta0113_RS10025	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Sta0113_RS10035	COG2267	carboxylic ester hydrolase activity
Sta0113_RS10040	COG0506	proline dehydrogenase activity
Sta0113_RS10045	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Sta0113_RS10050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Sta0113_RS10050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Sta0113_RS10060	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Sta0113_RS10060	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Sta0113_RS10070	COG5632	N-Acetylmuramoyl-L-alanine amidase
Sta0113_RS10070	COG3266	domain, Protein
Sta0113_RS10070	COG4193	domain, Protein
Sta0113_RS10095	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Sta0113_RS10105	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Sta0113_RS10110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Sta0113_RS10115	COG0656	L-ascorbic acid biosynthetic process
Sta0113_RS10125	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Sta0113_RS10130	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Sta0113_RS10135	COG1506	peptidase
Sta0113_RS10140	COG0494	nUDIX hydrolase
Sta0113_RS10145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Sta0113_RS10155	COG0318	PFAM AMP-dependent synthetase and ligase
Sta0113_RS10205	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Sta0113_RS10215	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Sta0113_RS10220	COG2329	Antibiotic biosynthesis monooxygenase
Sta0113_RS10225	COG4473	ABC transporter
Sta0113_RS10230	COG1131	(ABC) transporter
Sta0113_RS10235	COG0537	adenosine 5'-monophosphoramidase activity
Sta0113_RS10250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Sta0113_RS10260	COG4717	serine-type aminopeptidase activity
Sta0113_RS10270	COG3679	Belongs to the UPF0342 family
Sta0113_RS10275	COG4399	Belongs to the UPF0754 family
Sta0113_RS10285	COG2197	response regulator
Sta0113_RS10290	COG4585	Histidine kinase
Sta0113_RS10290	COG2203	Gaf domain
Sta0113_RS10295	COG0564	pseudouridine synthase activity
Sta0113_RS10300	COG0114	fumarate hydratase activity
Sta0113_RS10315	COG0363	glucosamine-6-phosphate deaminase activity
Sta0113_RS10325	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Sta0113_RS10335	COG1126	abc transporter atp-binding protein
Sta0113_RS10340	COG0765	amino acid transport
Sta0113_RS10510	COG0735	belongs to the Fur family
Sta0113_RS10515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Sta0113_RS10525	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Sta0113_RS10530	COG4129	membrane
Sta0113_RS10540	COG3557	Belongs to the UPF0374 family
Sta0113_RS10545	COG1194	a g-specific adenine glycosylase
Sta0113_RS10550	COG1988	membrane-bound metal-dependent
Sta0113_RS10560	COG4172	Belongs to the ABC transporter superfamily
Sta0113_RS10570	COG2137	regulation of response to DNA damage stimulus
Sta0113_RS10575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Sta0113_RS10585	COG0693	protein deglycase activity
Sta0113_RS10595	COG0535	radical SAM domain protein
Sta0113_RS10600	COG1607	acyl-coa hydrolase
Sta0113_RS10605	COG2309	aminopeptidase activity
Sta0113_RS10610	COG4840	Belongs to the UPF0435 family
Sta0113_RS10615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Sta0113_RS10625	COG1295	ribonuclease BN
Sta0113_RS10630	COG2197	response regulator
Sta0113_RS10655	COG0024	Methionine aminopeptidase
Sta0113_RS10660	COG4129	membrane
Sta0113_RS10680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Sta0113_RS10690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Sta0113_RS10695	COG1597	lipid kinase activity
Sta0113_RS10700	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Sta0113_RS10705	COG0154	amidase activity
Sta0113_RS10710	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Sta0113_RS10715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Sta0113_RS10720	COG4851	CamS sex pheromone cAM373 precursor
Sta0113_RS10725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Sta0113_RS10730	COG0210	DNA helicase
Sta0113_RS10735	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
Sta0113_RS10740	COG4496	protein, YerC YecD
Sta0113_RS10745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Sta0113_RS10755	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
Sta0113_RS10760	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Sta0113_RS10765	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Sta0113_RS10775	COG0077	Prephenate dehydratase
Sta0113_RS10790	COG1335	isochorismatase
Sta0113_RS10795	COG1227	inorganic diphosphatase activity
Sta0113_RS10800	COG1012	belongs to the aldehyde dehydrogenase family
Sta0113_RS10805	COG2706	6-phosphogluconolactonase activity
Sta0113_RS10840	COG1131	(ABC) transporter
Sta0113_RS10855	COG1725	Transcriptional regulator
Sta0113_RS10890	COG0459	protein refolding
Sta0113_RS10895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Sta0113_RS10920	COG4512	PFAM Accessory gene regulator B
Sta0113_RS10935	COG3279	Response regulator of the LytR AlgR family
Sta0113_RS10940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Sta0113_RS10945	COG1621	beta-fructofuranosidase activity
Sta0113_RS10950	COG0004	ammonium transporteR
Sta0113_RS10955	COG0425	Belongs to the sulfur carrier protein TusA family
Sta0113_RS10960	COG2391	methyltransferase activity
Sta0113_RS10965	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Sta0113_RS10970	COG0488	(ABC) transporter
Sta0113_RS10975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Sta0113_RS10980	COG0456	acetyltransferase
Sta0113_RS10985	COG1214	PFAM Peptidase M22, glycoprotease
Sta0113_RS10990	COG0802	atpase or kinase
Sta0113_RS10995	COG0129	dihydroxy-acid dehydratase activity
Sta0113_RS11000	COG0028	Belongs to the TPP enzyme family
Sta0113_RS11010	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Sta0113_RS11015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Sta0113_RS11020	COG0473	3-isopropylmalate dehydrogenase activity
Sta0113_RS11025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Sta0113_RS11030	COG0066	3-isopropylmalate dehydratase activity