locus-tag	class	description
NZD48_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NZD48_RS00010	COG0592	DNA-directed DNA polymerase activity
NZD48_RS00040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NZD48_RS00045	COG2986	histidine ammonia-lyase
NZD48_RS00050	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NZD48_RS00125	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NZD48_RS00135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NZD48_RS00140	COG4241	membrane
NZD48_RS00145	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NZD48_RS00150	COG0359	binds to the 23S rRNA
NZD48_RS00155	COG0305	Participates in initiation and elongation during chromosome replication
NZD48_RS00160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NZD48_RS00185	COG5002	protein histidine kinase activity
NZD48_RS00190	COG4863	YycH protein
NZD48_RS00200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NZD48_RS00215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NZD48_RS00225	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NZD48_RS00305	COG2030	dehydratase
NZD48_RS00310	COG0584	glycerophosphoryl diester phosphodiesterase
NZD48_RS00315	COG3425	synthase
NZD48_RS00375	COG0741	lytic transglycosylase activity
NZD48_RS00375	COG0791	NLP P60 protein
NZD48_RS00405	COG2946	Replication initiation factor
NZD48_RS00415	COG1674	ftsk spoiiie
NZD48_RS00440	COG0640	Transcriptional regulator
NZD48_RS00445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NZD48_RS00450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NZD48_RS00460	COG2217	Heavy metal translocating P-type atpase
NZD48_RS00465	COG1388	LysM domain
NZD48_RS00490	COG1129	ABC transporter
NZD48_RS00495	COG1132	(ABC) transporter
NZD48_RS00495	COG2375	cellular response to nickel ion
NZD48_RS00500	COG1132	(ABC) transporter
NZD48_RS00510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NZD48_RS00515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NZD48_RS00520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NZD48_RS00525	COG2205	protein histidine kinase activity
NZD48_RS00530	COG0745	RESPONSE REGULATOR receiver
NZD48_RS00540	COG2423	ornithine cyclodeaminase activity
NZD48_RS00545	COG4264	IucA IucC family
NZD48_RS00550	COG2814	Major facilitator Superfamily
NZD48_RS00555	COG4264	IucA IucC family
NZD48_RS00560	COG4264	IucA IucC family
NZD48_RS00570	COG0019	diaminopimelate decarboxylase activity
NZD48_RS00575	COG1475	DNA binding
NZD48_RS00590	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NZD48_RS00595	COG2814	Major facilitator Superfamily
NZD48_RS00610	COG0039	L-malate dehydrogenase activity
NZD48_RS00615	COG1328	CTP reductase activity
NZD48_RS00620	COG0602	queuosine metabolic process
NZD48_RS00705	COG3620	sequence-specific DNA binding
NZD48_RS00780	COG3942	CHAP domain
NZD48_RS00780	COG1705	Flagellar rod assembly protein muramidase FlgJ
NZD48_RS00795	COG4716	Myosin-crossreactive antigen
NZD48_RS00805	COG3443	Belongs to the bacterial solute-binding protein 9 family
NZD48_RS00805	COG0803	Belongs to the bacterial solute-binding protein 9 family
NZD48_RS00810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NZD48_RS00815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NZD48_RS00820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NZD48_RS00840	COG3655	Transcriptional regulator
NZD48_RS00845	COG2723	6-phospho-beta-galactosidase activity
NZD48_RS00850	COG2188	Transcriptional regulator
NZD48_RS00855	COG0456	acetyltransferase
NZD48_RS00860	COG2311	Membrane
NZD48_RS00880	COG2188	Transcriptional regulator
NZD48_RS00885	COG0813	purine-nucleoside phosphorylase activity
NZD48_RS00890	COG2814	Major facilitator Superfamily
NZD48_RS00945	COG0702	epimerase
NZD48_RS00955	COG0415	Belongs to the DNA photolyase family
NZD48_RS00980	COG0477	Major facilitator Superfamily
NZD48_RS00995	COG1174	glycine betaine transport
NZD48_RS01005	COG1174	glycine betaine transport
NZD48_RS01025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NZD48_RS01060	COG0579	oxidoreductase
NZD48_RS01065	COG1755	Isoprenylcysteine carboxyl methyltransferase
NZD48_RS01070	COG1113	amino acid transport
NZD48_RS01085	COG0745	RESPONSE REGULATOR receiver
NZD48_RS01105	COG2205	protein histidine kinase activity
NZD48_RS01115	COG0745	RESPONSE REGULATOR receiver
NZD48_RS01120	COG2205	protein histidine kinase activity
NZD48_RS01125	COG1136	(ABC) transporter
NZD48_RS01145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NZD48_RS01180	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NZD48_RS01185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NZD48_RS01190	COG0156	8-amino-7-oxononanoate synthase activity
NZD48_RS01205	COG1620	l-lactate permease
NZD48_RS01225	COG1073	alpha beta
NZD48_RS01250	COG0384	phenazine biosynthesis protein PhzF
NZD48_RS01255	COG0183	Belongs to the thiolase family
NZD48_RS01265	COG1960	acyl-CoA dehydrogenase activity
NZD48_RS01270	COG0318	PFAM AMP-dependent synthetase and ligase
NZD48_RS01300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NZD48_RS01305	COG0730	response to heat
NZD48_RS01310	COG1937	Protein conserved in bacteria
NZD48_RS01315	COG2210	Belongs to the sulfur carrier protein TusA family
NZD48_RS01320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD48_RS01325	COG1609	Transcriptional regulator
NZD48_RS01330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NZD48_RS01335	COG1869	D-ribose catabolic process
NZD48_RS01340	COG1129	ABC transporter
NZD48_RS01345	COG1172	Belongs to the binding-protein-dependent transport system permease family
NZD48_RS01350	COG1879	ABC-type sugar transport system periplasmic component
NZD48_RS01370	COG3314	Sporulation integral membrane protein YlbJ
NZD48_RS01390	COG1012	belongs to the aldehyde dehydrogenase family
NZD48_RS01400	COG1028	Short-chain dehydrogenase reductase Sdr
NZD48_RS01405	COG3192	ethanolamine utilization protein
NZD48_RS01420	COG3711	transcriptional antiterminator
NZD48_RS01425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZD48_RS01435	COG3037	sugar-specific permease SgaT UlaA
NZD48_RS01440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NZD48_RS01485	COG3588	fructose-bisphosphate aldolase
NZD48_RS01580	COG2814	Major facilitator Superfamily
NZD48_RS01585	COG1335	isochorismatase
NZD48_RS01615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NZD48_RS01620	COG2814	Major facilitator Superfamily
NZD48_RS01625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NZD48_RS01635	COG1115	amino acid carrier protein
NZD48_RS01645	COG0741	lytic transglycosylase activity
NZD48_RS01650	COG0477	Major facilitator Superfamily
NZD48_RS01655	COG0668	transmembrane transport
NZD48_RS01665	COG4195	phage-related replication protein
NZD48_RS01670	COG4485	Bacterial membrane protein, YfhO
NZD48_RS01690	COG2843	Capsule synthesis protein
NZD48_RS01710	COG3568	Endonuclease Exonuclease Phosphatase
NZD48_RS01725	COG2205	protein histidine kinase activity
NZD48_RS01730	COG0745	RESPONSE REGULATOR receiver
NZD48_RS01735	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
NZD48_RS01755	COG0586	Pfam SNARE associated Golgi protein
NZD48_RS01765	COG1785	Belongs to the alkaline phosphatase family
NZD48_RS01770	COG1785	Belongs to the alkaline phosphatase family
NZD48_RS01800	COG1510	regulation of RNA biosynthetic process
NZD48_RS01805	COG1012	belongs to the aldehyde dehydrogenase family
NZD48_RS01810	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NZD48_RS01815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NZD48_RS01825	COG0107	imidazoleglycerol-phosphate synthase activity
NZD48_RS01830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NZD48_RS01845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NZD48_RS01850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NZD48_RS01860	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NZD48_RS01875	COG2271	Major facilitator Superfamily
NZD48_RS01880	COG2376	Dihydroxyacetone kinase
NZD48_RS01885	COG1461	Dihydroxyacetone kinase
NZD48_RS01900	COG2824	Alkylphosphonate utilization operon protein PhnA
NZD48_RS01905	COG1012	belongs to the aldehyde dehydrogenase family
NZD48_RS01920	COG0596	Alpha beta hydrolase
NZD48_RS01930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZD48_RS01930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NZD48_RS01930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NZD48_RS01935	COG2814	Major facilitator Superfamily
NZD48_RS01945	COG3942	CHAP domain
NZD48_RS01945	COG1705	Flagellar rod assembly protein muramidase FlgJ
NZD48_RS01965	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NZD48_RS01970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NZD48_RS01970	COG0463	Glycosyl transferase, family 2
NZD48_RS01990	COG1263	PTS System
NZD48_RS01990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NZD48_RS02000	COG0778	Nitroreductase
NZD48_RS02005	COG3001	Fructosamine kinase
NZD48_RS02025	COG1136	(ABC) transporter
NZD48_RS02030	COG0577	efflux transmembrane transporter activity
NZD48_RS02035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NZD48_RS02045	COG0745	RESPONSE REGULATOR receiver
NZD48_RS02050	COG5002	protein histidine kinase activity
NZD48_RS02065	COG4413	Urea transporter
NZD48_RS02075	COG0832	Belongs to the urease beta subunit family
NZD48_RS02080	COG0804	urea catabolic process
NZD48_RS02095	COG0717	Belongs to the dCTP deaminase family
NZD48_RS02100	COG0523	cobalamin synthesis protein
NZD48_RS02110	COG1114	Component of the transport system for branched-chain amino acids
NZD48_RS02115	COG3189	MarR family transcriptional regulator
NZD48_RS02135	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NZD48_RS02140	COG4605	iron ion homeostasis
NZD48_RS02145	COG4604	ABC transporter, ATP-binding protein
NZD48_RS02150	COG4607	ABC-type enterochelin transport system periplasmic component
NZD48_RS02155	COG1846	Transcriptional regulator
NZD48_RS02160	COG0778	Nitroreductase
NZD48_RS02165	COG2357	RelA SpoT domain protein
NZD48_RS02200	COG2814	Major facilitator Superfamily
NZD48_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
NZD48_RS02215	COG0753	catalase activity
NZD48_RS02240	COG1028	Short-chain dehydrogenase reductase Sdr
NZD48_RS02265	COG3835	regulator
NZD48_RS02270	COG3961	Belongs to the TPP enzyme family
NZD48_RS02275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NZD48_RS02280	COG0512	Glutamine amidotransferase of anthranilate synthase
NZD48_RS02285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NZD48_RS02290	COG0134	indole-3-glycerol-phosphate synthase activity
NZD48_RS02300	COG0133	tryptophan synthase activity
NZD48_RS02305	COG0159	tryptophan synthase activity
NZD48_RS02325	COG0277	FAD linked oxidase domain protein
NZD48_RS02330	COG0247	lactate metabolic process
NZD48_RS02335	COG1132	(ABC) transporter
NZD48_RS02340	COG1132	(ABC) transporter
NZD48_RS02345	COG0346	lactoylglutathione lyase activity
NZD48_RS02350	COG3871	stress protein (general stress protein 26)
NZD48_RS02355	COG1115	amino acid carrier protein
NZD48_RS02365	COG2814	Major facilitator Superfamily
NZD48_RS02370	COG2271	Major facilitator Superfamily
NZD48_RS02375	COG3764	Sortase (surface protein transpeptidase)
NZD48_RS02380	COG1929	Belongs to the glycerate kinase type-1 family
NZD48_RS02385	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
NZD48_RS02400	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NZD48_RS02410	COG0702	epimerase
NZD48_RS02420	COG0444	Belongs to the ABC transporter superfamily
NZD48_RS02425	COG4608	Belongs to the ABC transporter superfamily
NZD48_RS02430	COG0601	transmembrane transport
NZD48_RS02435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NZD48_RS02450	COG1760	l-serine dehydratase
NZD48_RS02455	COG1760	l-serine dehydratase
NZD48_RS02475	COG0471	metal ion transport
NZD48_RS02490	COG0454	-acetyltransferase
NZD48_RS02505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NZD48_RS02510	COG2146	nitrite reductase [NAD(P)H] activity
NZD48_RS02515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NZD48_RS02515	COG1648	precorrin-2 dehydrogenase activity
NZD48_RS02520	COG0737	Belongs to the 5'-nucleotidase family
NZD48_RS02525	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NZD48_RS02530	COG1140	nitrate reductase beta subunit
NZD48_RS02535	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NZD48_RS02540	COG2181	nitrate reductase activity
NZD48_RS02550	COG4585	Histidine kinase
NZD48_RS02555	COG2197	response regulator
NZD48_RS02560	COG2223	nitrite transmembrane transporter activity
NZD48_RS02565	COG4187	Peptidase family M20/M25/M40
NZD48_RS02575	COG1363	Peptidase, m42
NZD48_RS02580	COG0697	spore germination
NZD48_RS02595	COG2807	transmembrane transport
NZD48_RS02600	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NZD48_RS02625	COG1846	Transcriptional regulator
NZD48_RS02630	COG1283	sodium-dependent phosphate transmembrane transporter activity
NZD48_RS02655	COG0492	ferredoxin-NADP+ reductase activity
NZD48_RS02660	COG2814	Major facilitator Superfamily
NZD48_RS02665	COG0604	alcohol dehydrogenase
NZD48_RS02680	COG1620	l-lactate permease
NZD48_RS02695	COG3850	Histidine kinase
NZD48_RS02695	COG5002	protein histidine kinase activity
NZD48_RS02710	COG1136	(ABC) transporter
NZD48_RS02740	COG0657	acetylesterase activity
NZD48_RS02760	COG1304	FMN binding
NZD48_RS02765	COG0523	cobalamin synthesis protein
NZD48_RS02770	COG0786	glutamate:sodium symporter activity
NZD48_RS02775	COG2207	Transcriptional regulator
NZD48_RS02785	COG1757	Na H antiporter
NZD48_RS02795	COG3152	Membrane
NZD48_RS02800	COG4152	abc transporter atp-binding protein
NZD48_RS02805	COG1668	transmembrane transport
NZD48_RS02810	COG1742	UPF0060 membrane protein
NZD48_RS02815	COG2017	converts alpha-aldose to the beta-anomer
NZD48_RS02825	COG2258	MOSC domain
NZD48_RS02830	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NZD48_RS02840	COG1266	CAAX protease self-immunity
NZD48_RS02850	COG0583	DNA-binding transcription factor activity
NZD48_RS02855	COG3314	Sporulation integral membrane protein YlbJ
NZD48_RS02860	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NZD48_RS02865	COG1228	amidohydrolase
NZD48_RS02870	COG1473	amidohydrolase
NZD48_RS02890	COG0385	Bile acid
NZD48_RS02895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NZD48_RS02920	COG1113	amino acid transport
NZD48_RS02950	COG1316	TRANSCRIPTIONal
NZD48_RS02955	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NZD48_RS02960	COG3383	formate dehydrogenase (NAD+) activity
NZD48_RS03005	COG1757	Na H antiporter
NZD48_RS03015	COG3942	CHAP domain
NZD48_RS03040	COG1960	acyl-CoA dehydrogenase activity
NZD48_RS03045	COG2832	Protein of unknown function (DUF454)
NZD48_RS03050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NZD48_RS03055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NZD48_RS03065	COG2186	Transcriptional regulator
NZD48_RS03075	COG1268	BioY protein
NZD48_RS03090	COG0725	ABC transporter, periplasmic molybdate-binding protein
NZD48_RS03095	COG4149	molybdate abc transporter
NZD48_RS03100	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NZD48_RS03105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NZD48_RS03110	COG0521	Mo-molybdopterin cofactor biosynthetic process
NZD48_RS03115	COG0315	cyclic pyranopterin monophosphate synthase activity
NZD48_RS03125	COG1763	Mo-molybdopterin cofactor biosynthetic process
NZD48_RS03130	COG0314	molybdopterin synthase activity
NZD48_RS03140	COG0746	molybdenum cofactor guanylyltransferase activity
NZD48_RS03170	COG2348	transferase activity, transferring amino-acyl groups
NZD48_RS03175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NZD48_RS03180	COG0436	Aminotransferase
NZD48_RS03210	COG2252	PERMEase
NZD48_RS03220	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NZD48_RS03225	COG0088	Forms part of the polypeptide exit tunnel
NZD48_RS03230	COG0089	rRNA binding
NZD48_RS03235	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NZD48_RS03240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NZD48_RS03245	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NZD48_RS03250	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NZD48_RS03260	COG0255	Belongs to the universal ribosomal protein uL29 family
NZD48_RS03270	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NZD48_RS03275	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NZD48_RS03285	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NZD48_RS03290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NZD48_RS03310	COG1841	ribosomal large subunit assembly
NZD48_RS03320	COG0201	protein transport
NZD48_RS03335	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NZD48_RS03345	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NZD48_RS03350	COG0202	RNA polymerase activity
NZD48_RS03355	COG0203	ribosomal protein L17
NZD48_RS03365	COG1122	ATPase activity
NZD48_RS03375	COG0101	tRNA pseudouridine synthase activity
NZD48_RS03445	COG0456	acetyltransferase
NZD48_RS03470	COG0789	Transcriptional regulator
NZD48_RS03475	COG2226	methyltransferase
NZD48_RS03510	COG3684	Belongs to the aldolase LacD family
NZD48_RS03525	COG2723	6-phospho-beta-galactosidase activity
NZD48_RS03530	COG0604	alcohol dehydrogenase
NZD48_RS03535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NZD48_RS03540	COG2814	Major facilitator Superfamily
NZD48_RS03545	COG4264	IucA IucC family
NZD48_RS03550	COG2814	Major facilitator Superfamily
NZD48_RS03555	COG4264	IucA IucC family
NZD48_RS03560	COG3457	Alanine racemase
NZD48_RS03565	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NZD48_RS03570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NZD48_RS03575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NZD48_RS03585	COG1988	membrane-bound metal-dependent
NZD48_RS03590	COG4284	Utp--glucose-1-phosphate uridylyltransferase
NZD48_RS03595	COG1272	protein, Hemolysin III
NZD48_RS03610	COG2814	Major facilitator Superfamily
NZD48_RS03615	COG0489	protein tyrosine kinase activity
NZD48_RS03680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NZD48_RS03690	COG1119	ATPase activity
NZD48_RS03705	COG2186	Transcriptional regulator
NZD48_RS03710	COG1482	cell wall glycoprotein biosynthetic process
NZD48_RS03725	COG1757	Na H antiporter
NZD48_RS03735	COG0813	purine-nucleoside phosphorylase activity
NZD48_RS03770	COG5146	pantothenate kinase activity
NZD48_RS03785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NZD48_RS03795	COG0504	CTP synthase activity
NZD48_RS03805	COG0191	fructose-bisphosphate aldolase activity
NZD48_RS03810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NZD48_RS03815	COG1733	regulation of RNA biosynthetic process
NZD48_RS03820	COG1012	belongs to the aldehyde dehydrogenase family
NZD48_RS03825	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NZD48_RS03830	COG0254	rRNA binding
NZD48_RS03840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NZD48_RS03845	COG2890	protein-(glutamine-N5) methyltransferase activity
NZD48_RS03850	COG0009	L-threonylcarbamoyladenylate synthase
NZD48_RS03855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NZD48_RS03860	COG4475	Protein of unknown function (DUF436)
NZD48_RS03870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NZD48_RS03875	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NZD48_RS03885	COG0356	it plays a direct role in the translocation of protons across the membrane
NZD48_RS03890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NZD48_RS03900	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NZD48_RS03905	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NZD48_RS03910	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NZD48_RS03930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NZD48_RS03940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NZD48_RS03965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NZD48_RS03975	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NZD48_RS03980	COG0352	thiamine-phosphate diphosphorylase activity
NZD48_RS03985	COG0706	membrane insertase activity
NZD48_RS03990	COG1418	mRNA catabolic process
NZD48_RS04000	COG1937	Protein conserved in bacteria
NZD48_RS04010	COG2608	mercury ion transmembrane transporter activity
NZD48_RS04015	COG2217	Heavy metal translocating P-type atpase
NZD48_RS04025	COG0772	Belongs to the SEDS family
NZD48_RS04035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NZD48_RS04040	COG0513	Belongs to the DEAD box helicase family
NZD48_RS04060	COG0736	holo-[acyl-carrier-protein] synthase activity
NZD48_RS04075	COG2337	Toxic component of a toxin-antitoxin (TA) module
NZD48_RS04080	COG2208	phosphoserine phosphatase activity
NZD48_RS04095	COG1191	sigma factor activity
NZD48_RS04100	COG2183	response to ionizing radiation
NZD48_RS04105	COG3091	SprT-like family
NZD48_RS04135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NZD48_RS04140	COG0066	3-isopropylmalate dehydratase activity
NZD48_RS04145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NZD48_RS04155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NZD48_RS04165	COG0440	acetolactate synthase activity
NZD48_RS04170	COG0028	Belongs to the TPP enzyme family
NZD48_RS04175	COG0129	dihydroxy-acid dehydratase activity
NZD48_RS04180	COG0802	atpase or kinase
NZD48_RS04185	COG1214	PFAM Peptidase M22, glycoprotease
NZD48_RS04190	COG0456	acetyltransferase
NZD48_RS04195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NZD48_RS04200	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NZD48_RS04205	COG0488	(ABC) transporter
NZD48_RS04215	COG2391	methyltransferase activity
NZD48_RS04220	COG0425	Belongs to the sulfur carrier protein TusA family
NZD48_RS04225	COG1621	beta-fructofuranosidase activity
NZD48_RS04245	COG4512	PFAM Accessory gene regulator B
NZD48_RS04285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NZD48_RS04305	COG1131	(ABC) transporter
NZD48_RS04315	COG1802	Transcriptional regulator
NZD48_RS04320	COG1070	Carbohydrate kinase
NZD48_RS04325	COG2610	gluconate transmembrane transporter activity
NZD48_RS04330	COG4876	unkown
NZD48_RS04370	COG2706	6-phosphogluconolactonase activity
NZD48_RS04380	COG1012	belongs to the aldehyde dehydrogenase family
NZD48_RS04390	COG1227	inorganic diphosphatase activity
NZD48_RS04395	COG1335	isochorismatase
NZD48_RS04405	COG0077	Prephenate dehydratase
NZD48_RS04415	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NZD48_RS04420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NZD48_RS04425	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NZD48_RS04440	COG4496	protein, YerC YecD
NZD48_RS04450	COG0210	DNA helicase
NZD48_RS04455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NZD48_RS04460	COG4851	CamS sex pheromone cAM373 precursor
NZD48_RS04475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NZD48_RS04480	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NZD48_RS04490	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NZD48_RS04495	COG1597	lipid kinase activity
NZD48_RS04515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NZD48_RS04525	COG1528	Iron-storage protein
NZD48_RS04540	COG4129	membrane
NZD48_RS04570	COG0288	reversible hydration of carbon dioxide
NZD48_RS04575	COG1295	ribonuclease BN
NZD48_RS04585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NZD48_RS04590	COG4840	Belongs to the UPF0435 family
NZD48_RS04595	COG2309	aminopeptidase activity
NZD48_RS04600	COG1607	acyl-coa hydrolase
NZD48_RS04605	COG0535	radical SAM domain protein
NZD48_RS04615	COG0693	protein deglycase activity
NZD48_RS04620	COG0028	Belongs to the TPP enzyme family
NZD48_RS04625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NZD48_RS04630	COG2137	regulation of response to DNA damage stimulus
NZD48_RS04640	COG1388	LysM domain
NZD48_RS04640	COG1134	teichoic acid transport
NZD48_RS04650	COG1988	membrane-bound metal-dependent
NZD48_RS04655	COG1194	a g-specific adenine glycosylase
NZD48_RS04660	COG3557	Belongs to the UPF0374 family
NZD48_RS04670	COG0069	glutamate synthase activity
NZD48_RS04675	COG4129	membrane
NZD48_RS04680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NZD48_RS04685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NZD48_RS04695	COG0735	belongs to the Fur family
NZD48_RS04850	COG0765	amino acid transport
NZD48_RS04855	COG1126	abc transporter atp-binding protein
NZD48_RS04860	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NZD48_RS04870	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NZD48_RS04875	COG0363	glucosamine-6-phosphate deaminase activity
NZD48_RS04890	COG0114	fumarate hydratase activity
NZD48_RS04900	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NZD48_RS04905	COG0564	pseudouridine synthase activity
NZD48_RS04910	COG4585	Histidine kinase
NZD48_RS04910	COG2203	Gaf domain
NZD48_RS04915	COG2197	response regulator
NZD48_RS04925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NZD48_RS04950	COG0488	(ABC) transporter
NZD48_RS04985	COG4399	Belongs to the UPF0754 family
NZD48_RS04990	COG3679	Belongs to the UPF0342 family
NZD48_RS04995	COG0420	3'-5' exonuclease activity
NZD48_RS05000	COG4717	serine-type aminopeptidase activity
NZD48_RS05005	COG3481	metal-dependent phosphohydrolase, HD sub domain
NZD48_RS05010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NZD48_RS05020	COG1846	Transcriptional regulator
NZD48_RS05030	COG0537	adenosine 5'-monophosphoramidase activity
NZD48_RS05035	COG1131	(ABC) transporter
NZD48_RS05045	COG2329	Antibiotic biosynthesis monooxygenase
NZD48_RS05050	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NZD48_RS05060	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NZD48_RS05155	COG1302	Protein conserved in bacteria
NZD48_RS05165	COG0318	PFAM AMP-dependent synthetase and ligase
NZD48_RS05185	COG1506	peptidase
NZD48_RS05190	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NZD48_RS05195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NZD48_RS05205	COG0656	L-ascorbic acid biosynthetic process
NZD48_RS05215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NZD48_RS05230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NZD48_RS05245	COG1595	DNA-templated transcription, initiation
NZD48_RS05255	COG3266	domain, Protein
NZD48_RS05255	COG4193	domain, Protein
NZD48_RS05255	COG5632	N-Acetylmuramoyl-L-alanine amidase
NZD48_RS05265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NZD48_RS05265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NZD48_RS05280	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NZD48_RS05285	COG0506	proline dehydrogenase activity
NZD48_RS05295	COG2267	carboxylic ester hydrolase activity
NZD48_RS05300	COG0039	L-malate dehydrogenase activity
NZD48_RS05310	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NZD48_RS05315	COG1242	4 iron, 4 sulfur cluster binding
NZD48_RS05320	COG2814	Major facilitator Superfamily
NZD48_RS05325	COG0495	leucyl-tRNA aminoacylation
NZD48_RS05330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NZD48_RS05335	COG2081	HI0933 family
NZD48_RS05340	COG2244	polysaccharide biosynthetic process
NZD48_RS05345	COG1187	pseudouridine synthase activity
NZD48_RS05355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NZD48_RS05360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NZD48_RS05365	COG0510	thiamine kinase activity
NZD48_RS05375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD48_RS05385	COG1363	Peptidase, m42
NZD48_RS05390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NZD48_RS05395	COG4848	Belongs to the UPF0354 family
NZD48_RS05400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NZD48_RS05405	COG1674	ftsk spoiiie
NZD48_RS05410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NZD48_RS05415	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NZD48_RS05425	COG1605	Chorismate mutase
NZD48_RS05425	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NZD48_RS05430	COG1609	Transcriptional regulator
NZD48_RS05435	COG0123	including yeast histone deacetylase and acetoin utilization protein
NZD48_RS05440	COG0454	-acetyltransferase
NZD48_RS05445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NZD48_RS05450	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NZD48_RS05455	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NZD48_RS05470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NZD48_RS05475	COG0204	Acyl-transferase
NZD48_RS05485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NZD48_RS05490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NZD48_RS05495	COG1764	response to oxidative stress
NZD48_RS05500	COG0584	glycerophosphoryl diester phosphodiesterase
NZD48_RS05510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NZD48_RS05515	COG1956	GAF domain-containing protein
NZD48_RS05520	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NZD48_RS05525	COG1104	cysteine desulfurase activity
NZD48_RS05530	COG0301	tRNA thio-modification
NZD48_RS05535	COG0730	response to heat
NZD48_RS05540	COG0616	signal peptide processing
NZD48_RS05545	COG1714	RDD family
NZD48_RS05550	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NZD48_RS05555	COG0827	DNA restriction-modification system
NZD48_RS05560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NZD48_RS05565	COG0589	response to stress
NZD48_RS05575	COG0006	proline dipeptidase activity
NZD48_RS05580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NZD48_RS05590	COG4109	DRTGG domain
NZD48_RS05595	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NZD48_RS05600	COG0587	DNA-directed DNA polymerase activity
NZD48_RS05605	COG0281	malic enzyme
NZD48_RS05610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NZD48_RS05615	COG0825	malonyl-CoA metabolic process
NZD48_RS05620	COG0205	6-phosphofructokinase activity
NZD48_RS05625	COG0469	pyruvate kinase activity
NZD48_RS05630	COG0372	Belongs to the citrate synthase family
NZD48_RS05640	COG0745	RESPONSE REGULATOR receiver
NZD48_RS05645	COG5002	protein histidine kinase activity
NZD48_RS05650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NZD48_RS05650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NZD48_RS05655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NZD48_RS05665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NZD48_RS05670	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NZD48_RS05675	COG3611	Membrane attachment protein
NZD48_RS05680	COG1484	DNA-dependent DNA replication
NZD48_RS05685	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NZD48_RS05690	COG0833	amino acid
NZD48_RS05695	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NZD48_RS05700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NZD48_RS05705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NZD48_RS05720	COG0544	peptidyl-prolyl cis-trans isomerase activity
NZD48_RS05730	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NZD48_RS05735	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NZD48_RS05740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NZD48_RS05770	COG2818	Glycosylase
NZD48_RS05775	COG0525	valine-tRNA ligase activity
NZD48_RS05780	COG0285	dihydrofolate synthase activity
NZD48_RS05810	COG2249	NAD(P)H dehydrogenase (quinone) activity
NZD48_RS05815	COG0477	Major facilitator Superfamily
NZD48_RS05825	COG2003	Belongs to the UPF0758 family
NZD48_RS05840	COG1792	Involved in formation and maintenance of cell shape
NZD48_RS05850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NZD48_RS05855	COG2868	ribosomal protein
NZD48_RS05870	COG4492	Belongs to the UPF0735 family
NZD48_RS05875	COG0632	four-way junction helicase activity
NZD48_RS05895	COG1862	Preprotein translocase
NZD48_RS05900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NZD48_RS05900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NZD48_RS05905	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NZD48_RS05905	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NZD48_RS05910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NZD48_RS05920	COG1490	D-aminoacyl-tRNA deacylase activity
NZD48_RS05925	COG0860	N-Acetylmuramoyl-L-alanine amidase
NZD48_RS05935	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NZD48_RS05945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NZD48_RS05950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NZD48_RS05955	COG1959	2 iron, 2 sulfur cluster binding
NZD48_RS05980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NZD48_RS05985	COG1104	cysteine desulfurase activity
NZD48_RS05990	COG0482	sulfurtransferase activity
NZD48_RS06000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NZD48_RS06005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NZD48_RS06010	COG4472	Bacterial protein of unknown function (DUF965)
NZD48_RS06015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NZD48_RS06020	COG3906	Belongs to the UPF0473 family
NZD48_RS06025	COG4122	O-methyltransferase activity
NZD48_RS06030	COG0826	peptidase U32
NZD48_RS06035	COG0826	peptidase U32
NZD48_RS06040	COG0572	uridine kinase
NZD48_RS06045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NZD48_RS06050	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NZD48_RS06055	COG1984	allophanate hydrolase subunit 2
NZD48_RS06060	COG0511	ligase activity, forming carbon-carbon bonds
NZD48_RS06065	COG0439	Biotin carboxylase
NZD48_RS06070	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NZD48_RS06075	COG1914	H( )-stimulated, divalent metal cation uptake system
NZD48_RS06080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NZD48_RS06085	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NZD48_RS06090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NZD48_RS06100	COG1534	Rna-binding protein
NZD48_RS06110	COG1713	HD superfamily hydrolase involved in NAD metabolism
NZD48_RS06115	COG0799	negative regulation of ribosome biogenesis
NZD48_RS06120	COG2226	methyltransferase
NZD48_RS06125	COG1555	photosystem II stabilization
NZD48_RS06125	COG1596	polysaccharide export
NZD48_RS06130	COG2131	deaminase
NZD48_RS06135	COG0658	competence protein
NZD48_RS06135	COG2333	competence protein COMEC
NZD48_RS06140	COG1466	dna polymerase III delta subunit
NZD48_RS06145	COG0268	Binds directly to 16S ribosomal RNA
NZD48_RS06155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NZD48_RS06160	COG1420	regulation of RNA biosynthetic process
NZD48_RS06175	COG0484	heat shock protein binding
NZD48_RS06185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NZD48_RS06190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NZD48_RS06205	COG4864	UPF0365 protein
NZD48_RS06215	COG1702	phosphate starvation-inducible protein PhoH
NZD48_RS06220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NZD48_RS06230	COG0295	cytidine deaminase activity
NZD48_RS06235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NZD48_RS06240	COG1381	Involved in DNA repair and RecF pathway recombination
NZD48_RS06245	COG0423	glycine-tRNA ligase activity
NZD48_RS06250	COG0517	IMP dehydrogenase activity
NZD48_RS06255	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NZD48_RS06260	COG0358	DNA primase activity
NZD48_RS06265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NZD48_RS06270	COG2384	SAM-dependent methyltransferase
NZD48_RS06275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NZD48_RS06280	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NZD48_RS06285	COG0513	Belongs to the DEAD box helicase family
NZD48_RS06290	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NZD48_RS06295	COG1121	(ABC) transporter
NZD48_RS06300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NZD48_RS06310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NZD48_RS06320	COG0768	penicillin binding
NZD48_RS06325	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NZD48_RS06330	COG0573	inorganic phosphate transmembrane transporter activity
NZD48_RS06335	COG0581	inorganic phosphate transmembrane transporter activity
NZD48_RS06340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NZD48_RS06345	COG0704	Plays a role in the regulation of phosphate uptake
NZD48_RS06350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NZD48_RS06355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NZD48_RS06360	COG0705	Rhomboid family
NZD48_RS06365	COG4483	Protein conserved in bacteria
NZD48_RS06370	COG1940	carbohydrate kinase activity
NZD48_RS06375	COG0011	TIGRFAM Protein of
NZD48_RS06380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NZD48_RS06385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NZD48_RS06390	COG1459	type II secretion system
NZD48_RS06415	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NZD48_RS06420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NZD48_RS06425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NZD48_RS06430	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NZD48_RS06435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NZD48_RS06440	COG0095	Lipoate-protein ligase
NZD48_RS06455	COG0006	proline dipeptidase activity
NZD48_RS06460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NZD48_RS06465	COG0511	ligase activity, forming carbon-carbon bonds
NZD48_RS06470	COG0439	Biotin carboxylase
NZD48_RS06475	COG1302	Protein conserved in bacteria
NZD48_RS06485	COG1570	exodeoxyribonuclease VII activity
NZD48_RS06500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NZD48_RS06505	COG1438	arginine binding
NZD48_RS06510	COG0497	DNA recombination
NZD48_RS06515	COG0280	phosphate acetyltransferase
NZD48_RS06520	COG3426	butyrate kinase activity
NZD48_RS06525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NZD48_RS06530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NZD48_RS06535	COG0022	dehydrogenase e1 component
NZD48_RS06540	COG0508	dehydrogenase complex catalyzes the overall conversion of
NZD48_RS06550	COG4129	membrane
NZD48_RS06560	COG2195	Cleaves the N-terminal amino acid of tripeptides
NZD48_RS06575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NZD48_RS06580	COG1234	tRNA 3'-trailer cleavage
NZD48_RS06585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NZD48_RS06595	COG0667	Aldo Keto reductase
NZD48_RS06600	COG0494	nUDIX hydrolase
NZD48_RS06605	COG0735	belongs to the Fur family
NZD48_RS06610	COG4974	Belongs to the 'phage' integrase family
NZD48_RS06620	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NZD48_RS06625	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NZD48_RS06630	COG1187	pseudouridine synthase activity
NZD48_RS06635	COG0745	RESPONSE REGULATOR receiver
NZD48_RS06640	COG5002	protein histidine kinase activity
NZD48_RS06650	COG1141	Ferredoxin
NZD48_RS06660	COG0514	ATP-dependent DNA helicase (RecQ)
NZD48_RS06670	COG0492	ferredoxin-NADP+ reductase activity
NZD48_RS06675	COG0252	asparaginase activity
NZD48_RS06680	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NZD48_RS06685	COG0539	negative regulation of cytoplasmic translation
NZD48_RS06695	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NZD48_RS06710	COG2226	methyltransferase
NZD48_RS06715	COG0142	geranyltranstransferase activity
NZD48_RS06720	COG0105	UTP biosynthetic process
NZD48_RS06725	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NZD48_RS06730	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NZD48_RS06740	COG0457	Tetratricopeptide repeat
NZD48_RS06750	COG4347	Protein of unknown function (DUF1405)
NZD48_RS06755	COG2738	Putative neutral zinc metallopeptidase
NZD48_RS06760	COG1694	Mazg nucleotide pyrophosphohydrolase
NZD48_RS06765	COG0438	transferase activity, transferring glycosyl groups
NZD48_RS06785	COG0017	Asparaginyl-tRNA synthetase
NZD48_RS06790	COG3935	DnaD domain protein
NZD48_RS06795	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NZD48_RS06805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NZD48_RS06805	COG4499	WXG100 protein secretion system (Wss), protein YukC
NZD48_RS06810	COG3331	DNA recombination
NZD48_RS06820	COG4474	Belongs to the UPF0398 family
NZD48_RS06835	COG0116	Belongs to the methyltransferase superfamily
NZD48_RS06840	COG2962	Rard protein
NZD48_RS06850	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NZD48_RS06855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NZD48_RS06860	COG0328	RNA-DNA hybrid ribonuclease activity
NZD48_RS06865	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NZD48_RS06875	COG1413	lyase activity
NZD48_RS06885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NZD48_RS06905	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NZD48_RS06915	COG4479	Belongs to the UPF0346 family
NZD48_RS06935	COG0671	phosphoesterase, PA-phosphatase related
NZD48_RS06940	COG0745	RESPONSE REGULATOR receiver
NZD48_RS06945	COG5002	protein histidine kinase activity
NZD48_RS06970	COG0714	Associated with various cellular activities
NZD48_RS06975	COG4548	von Willebrand factor, type A
NZD48_RS06980	COG1114	Component of the transport system for branched-chain amino acids
NZD48_RS06985	COG3853	Toxic anion resistance protein (TelA)
NZD48_RS07005	COG1278	Cold shock
NZD48_RS07020	COG1473	amidohydrolase
NZD48_RS07030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NZD48_RS07035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NZD48_RS07040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NZD48_RS07045	COG0488	(ABC) transporter
NZD48_RS07050	COG2996	Protein conserved in bacteria
NZD48_RS07055	COG1105	Belongs to the carbohydrate kinase PfkB family
NZD48_RS07070	COG2348	transferase activity, transferring amino-acyl groups
NZD48_RS07075	COG2348	transferase activity, transferring amino-acyl groups
NZD48_RS07080	COG1363	Peptidase, m42
NZD48_RS07085	COG0287	Prephenate dehydrogenase
NZD48_RS07090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NZD48_RS07120	COG0628	permease
NZD48_RS07130	COG3711	transcriptional antiterminator
NZD48_RS07135	COG1115	amino acid carrier protein
NZD48_RS07140	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NZD48_RS07145	COG0187	DNA topoisomerase II activity
NZD48_RS07150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NZD48_RS07160	COG0824	Thioesterase
NZD48_RS07170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NZD48_RS07185	COG0420	3'-5' exonuclease activity
NZD48_RS07190	COG4846	Membrane protein involved in cytochrome C biogenesis
NZD48_RS07195	COG3763	UPF0154 protein
NZD48_RS07205	COG4224	UPF0291 protein
NZD48_RS07215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NZD48_RS07225	COG2340	Cysteine-rich secretory protein family
NZD48_RS07230	COG0516	GMP reductase activity
NZD48_RS07235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NZD48_RS07245	COG0753	catalase activity
NZD48_RS07250	COG0833	amino acid
NZD48_RS07260	COG0561	phosphatase activity
NZD48_RS07265	COG0083	homoserine kinase activity
NZD48_RS07270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NZD48_RS07275	COG0460	homoserine dehydrogenase
NZD48_RS07280	COG0527	aspartate kinase activity
NZD48_RS07310	COG2197	response regulator
NZD48_RS07315	COG4585	Histidine kinase
NZD48_RS07320	COG0842	Transport permease protein
NZD48_RS07325	COG4172	Belongs to the ABC transporter superfamily
NZD48_RS07360	COG0789	Transcriptional regulator
NZD48_RS07365	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NZD48_RS07370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NZD48_RS07380	COG1923	regulation of RNA biosynthetic process
NZD48_RS07395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NZD48_RS07405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NZD48_RS07410	COG1619	proteins homologs of microcin C7 resistance protein MccF
NZD48_RS07420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NZD48_RS07440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NZD48_RS07450	COG1013	pyruvate-flavodoxin oxidoreductase activity
NZD48_RS07455	COG0674	pyruvate-flavodoxin oxidoreductase activity
NZD48_RS07455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NZD48_RS07460	COG1692	metallophosphoesterase
NZD48_RS07480	COG1418	mRNA catabolic process
NZD48_RS07485	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NZD48_RS07490	COG1546	Belongs to the CinA family
NZD48_RS07490	COG1058	Belongs to the CinA family
NZD48_RS07510	COG1028	Short-chain dehydrogenase reductase Sdr
NZD48_RS07515	COG0612	Peptidase, M16
NZD48_RS07520	COG0612	Peptidase, M16
NZD48_RS07525	COG2188	Transcriptional regulator
NZD48_RS07535	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NZD48_RS07545	COG1185	polyribonucleotide nucleotidyltransferase activity
NZD48_RS07555	COG0196	riboflavin kinase activity
NZD48_RS07560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NZD48_RS07565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NZD48_RS07575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NZD48_RS07580	COG1358	cellular component organization or biogenesis
NZD48_RS07585	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NZD48_RS07590	COG0195	Participates in both transcription termination and antitermination
NZD48_RS07595	COG0779	Required for maturation of 30S ribosomal subunits
NZD48_RS07605	COG0442	prolyl-tRNA aminoacylation
NZD48_RS07615	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NZD48_RS07620	COG4589	Belongs to the CDS family
NZD48_RS07625	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NZD48_RS07630	COG0233	cytoplasmic translational termination
NZD48_RS07635	COG0528	UMP kinase activity
NZD48_RS07640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NZD48_RS07645	COG0052	Belongs to the universal ribosomal protein uS2 family
NZD48_RS07650	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NZD48_RS07655	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NZD48_RS07665	COG4974	Belongs to the 'phage' integrase family
NZD48_RS07670	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NZD48_RS07675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NZD48_RS07680	COG0758	DNA mediated transformation
NZD48_RS07690	COG0045	succinate-CoA ligase (ADP-forming) activity
NZD48_RS07715	COG4485	Bacterial membrane protein, YfhO
NZD48_RS07730	COG0335	large ribosomal subunit rRNA binding
NZD48_RS07735	COG0336	Belongs to the RNA methyltransferase TrmD family
NZD48_RS07745	COG0228	four-way junction DNA binding
NZD48_RS07750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NZD48_RS07755	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NZD48_RS07760	COG0552	protein localization to endoplasmic reticulum
NZD48_RS07765	COG1196	nuclear chromosome segregation
NZD48_RS07770	COG0571	ribonuclease III activity
NZD48_RS07775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NZD48_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
NZD48_RS07790	COG0416	fatty acid biosynthetic process
NZD48_RS07795	COG1349	DNA-binding transcription factor activity
NZD48_RS07800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NZD48_RS07805	COG1760	l-serine dehydratase
NZD48_RS07810	COG1760	l-serine dehydratase
NZD48_RS07820	COG1302	Protein conserved in bacteria
NZD48_RS07830	COG1564	THIamine pyrophosphokinase
NZD48_RS07835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NZD48_RS07840	COG1162	GTPase activity
NZD48_RS07845	COG2124	cytochrome p450
NZD48_RS07855	COG0631	protein serine/threonine phosphatase activity
NZD48_RS07860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NZD48_RS07865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NZD48_RS07865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NZD48_RS07870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NZD48_RS07885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NZD48_RS07890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NZD48_RS07895	COG1758	RNA polymerase activity
NZD48_RS07915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NZD48_RS07920	COG0284	orotidine-5'-phosphate decarboxylase activity
NZD48_RS07925	COG0167	dihydroorotate dehydrogenase activity
NZD48_RS07935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NZD48_RS07940	COG0505	Belongs to the CarA family
NZD48_RS07950	COG0540	Belongs to the ATCase OTCase family
NZD48_RS07960	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NZD48_RS07965	COG0564	pseudouridine synthase activity
NZD48_RS07970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NZD48_RS07980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NZD48_RS07985	COG3599	regulation of cell shape
NZD48_RS07995	COG0762	integral membrane protein
NZD48_RS08000	COG1799	cell septum assembly
NZD48_RS08005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NZD48_RS08010	COG1496	oxidoreductase activity
NZD48_RS08015	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NZD48_RS08020	COG0849	cell division
NZD48_RS08040	COG0768	penicillin binding
NZD48_RS08045	COG4839	cell division protein FtsL
NZD48_RS08050	COG0275	rRNA processing
NZD48_RS08060	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NZD48_RS08065	COG0454	-acetyltransferase
NZD48_RS08075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NZD48_RS08095	COG1388	LysM domain
NZD48_RS08095	COG5632	N-Acetylmuramoyl-L-alanine amidase
NZD48_RS08205	COG1783	phage Terminase large subunit
NZD48_RS08210	COG3728	DNA packaging
NZD48_RS08210	COG5484	DNA packaging
NZD48_RS08385	COG0582	viral genome integration into host DNA
NZD48_RS08395	COG2348	transferase activity, transferring amino-acyl groups
NZD48_RS08400	COG0739	heme binding
NZD48_RS08425	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NZD48_RS08430	COG1053	succinate dehydrogenase
NZD48_RS08435	COG2009	succinate dehydrogenase
NZD48_RS08440	COG0322	excinuclease ABC activity
NZD48_RS08445	COG3118	belongs to the thioredoxin family
NZD48_RS08450	COG1193	negative regulation of DNA recombination
NZD48_RS08455	COG1796	DNA polymerase
NZD48_RS08455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NZD48_RS08465	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NZD48_RS08470	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NZD48_RS08475	COG0072	phenylalanine-tRNA ligase activity
NZD48_RS08475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NZD48_RS08480	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NZD48_RS08485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NZD48_RS08490	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NZD48_RS08500	COG1323	Belongs to the UPF0348 family
NZD48_RS08505	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NZD48_RS08510	COG0742	ribosomal rna small subunit methyltransferase
NZD48_RS08530	COG3679	Belongs to the UPF0342 family
NZD48_RS08545	COG0109	protoheme IX farnesyltransferase activity
NZD48_RS08560	COG0772	Belongs to the SEDS family
NZD48_RS08565	COG4838	Belongs to the UPF0358 family
NZD48_RS08570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NZD48_RS08575	COG4896	Protein conserved in bacteria
NZD48_RS08590	COG1902	pentaerythritol trinitrate reductase activity
NZD48_RS08595	COG1217	gtp-binding protein TYPA
NZD48_RS08605	COG0483	inositol monophosphate 1-phosphatase activity
NZD48_RS08610	COG4493	Belongs to the UPF0637 family
NZD48_RS08625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NZD48_RS08630	COG1177	transmembrane transport
NZD48_RS08650	COG4476	Belongs to the UPF0223 family
NZD48_RS08680	COG0242	peptide deformylase activity
NZD48_RS08690	COG5503	Protein of unknown function (DUF1447)
NZD48_RS08695	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NZD48_RS08705	COG0569	domain protein
NZD48_RS08710	COG1294	oxidase, subunit
NZD48_RS08715	COG1271	oxidase subunit
NZD48_RS08725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NZD48_RS08740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NZD48_RS08755	COG4721	ABC-type cobalt transport system, permease component
NZD48_RS08760	COG1122	ATPase activity
NZD48_RS08770	COG0151	Belongs to the GarS family
NZD48_RS08775	COG0138	bifunctional purine biosynthesis protein purh
NZD48_RS08785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NZD48_RS08790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NZD48_RS08795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NZD48_RS08805	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NZD48_RS08810	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NZD48_RS08820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NZD48_RS08825	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NZD48_RS08830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NZD48_RS08830	COG1017	nitric oxide dioxygenase activity
NZD48_RS08840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NZD48_RS08850	COG1845	cytochrome c oxidase, subunit III
NZD48_RS08865	COG1134	teichoic acid transport
NZD48_RS08885	COG0438	transferase activity, transferring glycosyl groups
NZD48_RS08890	COG1215	transferase activity, transferring glycosyl groups
NZD48_RS08910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NZD48_RS08915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NZD48_RS08920	COG1316	TRANSCRIPTIONal
NZD48_RS08940	COG3594	Acyltransferase
NZD48_RS08945	COG0436	Aminotransferase
NZD48_RS08950	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NZD48_RS08955	COG2267	carboxylic ester hydrolase activity
NZD48_RS08960	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NZD48_RS08965	COG1169	isochorismate synthase
NZD48_RS08970	COG1575	Belongs to the MenA family. Type 1 subfamily
NZD48_RS08975	COG0390	transport system, permease component
NZD48_RS08980	COG4619	ABC transporter
NZD48_RS09045	COG0582	viral genome integration into host DNA
NZD48_RS09085	COG4873	Protein conserved in bacteria
NZD48_RS09100	COG0737	Belongs to the 5'-nucleotidase family
NZD48_RS09105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NZD48_RS09110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NZD48_RS09115	COG0861	Integral membrane protein TerC family
NZD48_RS09135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NZD48_RS09140	COG2814	Major facilitator Superfamily
NZD48_RS09150	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NZD48_RS09155	COG2382	esterase
NZD48_RS09160	COG1115	amino acid carrier protein
NZD48_RS09165	COG0628	permease
NZD48_RS09175	COG0569	domain protein
NZD48_RS09175	COG0475	glutathione-regulated potassium exporter activity
NZD48_RS09180	COG2239	Acts as a magnesium transporter
NZD48_RS09185	COG0564	pseudouridine synthase activity
NZD48_RS09190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NZD48_RS09195	COG2357	RelA SpoT domain protein
NZD48_RS09205	COG4116	CYTH
NZD48_RS09210	COG2346	COG2346, Truncated hemoglobins
NZD48_RS09215	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NZD48_RS09220	COG1164	Oligoendopeptidase f
NZD48_RS09230	COG4862	establishment of competence for transformation
NZD48_RS09235	COG1393	Belongs to the ArsC family
NZD48_RS09240	COG0180	Tryptophanyl-tRNA synthetase
NZD48_RS09245	COG4166	transmembrane transport
NZD48_RS09250	COG4608	Belongs to the ABC transporter superfamily
NZD48_RS09255	COG0444	Belongs to the ABC transporter superfamily
NZD48_RS09260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NZD48_RS09265	COG0601	transmembrane transport
NZD48_RS09290	COG0542	response to heat
NZD48_RS09295	COG2151	metal-sulfur cluster biosynthetic enzyme
NZD48_RS09300	COG0561	phosphatase activity
NZD48_RS09305	COG0446	pyridine nucleotide-disulphide oxidoreductase
NZD48_RS09315	COG0179	Fumarylacetoacetate (FAA) hydrolase
NZD48_RS09320	COG1074	ATP-dependent DNA helicase activity
NZD48_RS09335	COG0681	Belongs to the peptidase S26 family
NZD48_RS09340	COG0166	Belongs to the GPI family
NZD48_RS09345	COG0137	argininosuccinate synthase activity
NZD48_RS09350	COG0165	Argininosuccinate lyase
NZD48_RS09355	COG0584	glycerophosphoryl diester phosphodiesterase
NZD48_RS09370	COG1012	belongs to the aldehyde dehydrogenase family
NZD48_RS09375	COG1098	S1 RNA binding domain
NZD48_RS09385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NZD48_RS09395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NZD48_RS09395	COG2111	Na H antiporter
NZD48_RS09400	COG2111	Na H antiporter
NZD48_RS09405	COG1006	Multisubunit Na H antiporter MnhC subunit
NZD48_RS09410	COG0651	ATP synthesis coupled electron transport
NZD48_RS09415	COG1863	multisubunit Na H antiporter MnhE subunit
NZD48_RS09420	COG2212	antiporter activity
NZD48_RS09425	COG1320	monovalent cation:proton antiporter activity
NZD48_RS09435	COG2050	protein possibly involved in aromatic compounds catabolism
NZD48_RS09440	COG2056	Na+-H+ antiporter family
NZD48_RS09445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NZD48_RS09450	COG1252	NADH dehydrogenase
NZD48_RS09455	COG0316	Belongs to the HesB IscA family
NZD48_RS09465	COG1252	NADH dehydrogenase
NZD48_RS09470	COG4837	Protein of unknown function (DUF1462)
NZD48_RS09475	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NZD48_RS09480	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NZD48_RS09490	COG1696	Membrane protein involved in D-alanine export
NZD48_RS09505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NZD48_RS09515	COG2445	Protein of unknown function DUF86
NZD48_RS09525	COG4470	Protein conserved in bacteria
NZD48_RS09535	COG0737	Belongs to the 5'-nucleotidase family
NZD48_RS09540	COG0730	response to heat
NZD48_RS09545	COG1801	Protein of unknown function DUF72
NZD48_RS09550	COG4536	flavin adenine dinucleotide binding
NZD48_RS09555	COG0719	Fe-S assembly protein
NZD48_RS09560	COG0822	iron-sulfur transferase activity
NZD48_RS09570	COG0719	Fe-S assembly protein
NZD48_RS09575	COG0396	ATPase activity
NZD48_RS09585	COG1464	Belongs to the NlpA lipoprotein family
NZD48_RS09590	COG2011	ABC-type metal ion transport system permease component
NZD48_RS09595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NZD48_RS09600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NZD48_RS09605	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NZD48_RS09615	COG1393	Belongs to the ArsC family
NZD48_RS09620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NZD48_RS09630	COG0710	3-dehydroquinate dehydratase activity
NZD48_RS09635	COG0456	acetyltransferase
NZD48_RS09645	COG0477	Major facilitator Superfamily
NZD48_RS09665	COG0557	exoribonuclease II activity
NZD48_RS09670	COG1647	Serine aminopeptidase, S33
NZD48_RS09675	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NZD48_RS09685	COG0148	phosphopyruvate hydratase activity
NZD48_RS09690	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NZD48_RS09695	COG0149	triose-phosphate isomerase activity
NZD48_RS09700	COG0126	phosphoglycerate kinase activity
NZD48_RS09725	COG1090	epimerase
NZD48_RS09750	COG1278	Cold shock
NZD48_RS09760	COG0740	serine-type endopeptidase activity
NZD48_RS09765	COG1481	regulation of sporulation
NZD48_RS09770	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NZD48_RS09775	COG1660	Displays ATPase and GTPase activities
NZD48_RS09780	COG0492	ferredoxin-NADP+ reductase activity
NZD48_RS09795	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NZD48_RS09800	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NZD48_RS09830	COG3942	CHAP domain
NZD48_RS09840	COG0653	protein targeting
NZD48_RS09845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NZD48_RS09855	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NZD48_RS09865	COG1739	Uncharacterized protein family UPF0029
NZD48_RS09870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NZD48_RS09885	COG2199	diguanylate cyclase activity
NZD48_RS09900	COG2195	Cleaves the N-terminal amino acid of tripeptides
NZD48_RS09905	COG1929	Belongs to the glycerate kinase type-1 family
NZD48_RS09940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NZD48_RS09945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NZD48_RS09950	COG1780	Probably involved in ribonucleotide reductase function
NZD48_RS09960	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NZD48_RS09965	COG3104	oligopeptide transport
NZD48_RS09995	COG1174	glycine betaine transport
NZD48_RS10000	COG0517	IMP dehydrogenase activity
NZD48_RS10000	COG1125	glycine betaine transport
NZD48_RS10005	COG0514	ATP-dependent DNA helicase (RecQ)
NZD48_RS10010	COG0488	(ABC) transporter
NZD48_RS10020	COG1368	sulfuric ester hydrolase activity
NZD48_RS10050	COG0512	Glutamine amidotransferase of anthranilate synthase
NZD48_RS10050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NZD48_RS10060	COG0720	synthase
NZD48_RS10080	COG0463	Glycosyl transferase, family 2
NZD48_RS10085	COG1253	flavin adenine dinucleotide binding
NZD48_RS10090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NZD48_RS10090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NZD48_RS10090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NZD48_RS10095	COG1105	Belongs to the carbohydrate kinase PfkB family
NZD48_RS10100	COG1349	DNA-binding transcription factor activity
NZD48_RS10105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NZD48_RS10110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NZD48_RS10130	COG0039	L-malate dehydrogenase activity
NZD48_RS10140	COG4989	oxidoreductase activity
NZD48_RS10145	COG0523	cobalamin synthesis protein
NZD48_RS10155	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NZD48_RS10160	COG4988	ABC transporter
NZD48_RS10165	COG1968	undecaprenyl-diphosphatase activity
NZD48_RS10185	COG1671	Belongs to the UPF0178 family
NZD48_RS10190	COG1611	Belongs to the LOG family
NZD48_RS10220	COG2839	Protein conserved in bacteria
NZD48_RS10225	COG2814	Major facilitator Superfamily
NZD48_RS10230	COG0583	DNA-binding transcription factor activity
NZD48_RS10240	COG0217	transcriptional regulatory protein
NZD48_RS10250	COG2022	thiamine diphosphate biosynthetic process
NZD48_RS10255	COG2104	thiamine diphosphate biosynthetic process
NZD48_RS10255	COG2022	thiamine diphosphate biosynthetic process
NZD48_RS10270	COG3942	CHAP domain
NZD48_RS10270	COG1388	LysM domain
NZD48_RS10280	COG0306	phosphate transporter
NZD48_RS10285	COG1392	Phosphate transport regulator
NZD48_RS10290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NZD48_RS10300	COG0657	acetylesterase activity
NZD48_RS10305	COG3949	Membrane
NZD48_RS10310	COG0477	Major facilitator Superfamily
NZD48_RS10320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NZD48_RS10325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NZD48_RS10330	COG1120	ATPase activity
NZD48_RS10335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NZD48_RS10340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NZD48_RS10360	COG1132	(ABC) transporter
NZD48_RS10370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NZD48_RS10375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NZD48_RS10380	COG1682	transport, permease protein
NZD48_RS10385	COG1134	teichoic acid transport
NZD48_RS10390	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NZD48_RS10405	COG1121	(ABC) transporter
NZD48_RS10410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NZD48_RS10415	COG0803	Belongs to the bacterial solute-binding protein 9 family
NZD48_RS10430	COG1320	monovalent cation:proton antiporter activity
NZD48_RS10435	COG2212	antiporter activity
NZD48_RS10440	COG1863	multisubunit Na H antiporter MnhE subunit
NZD48_RS10450	COG1006	Multisubunit Na H antiporter MnhC subunit
NZD48_RS10455	COG2111	Na H antiporter
NZD48_RS10460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NZD48_RS10460	COG2111	Na H antiporter
NZD48_RS10465	COG0582	viral genome integration into host DNA
NZD48_RS10515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NZD48_RS10520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NZD48_RS10540	COG1078	dGTPase activity
NZD48_RS10550	COG0655	NAD(P)H dehydrogenase (quinone) activity
NZD48_RS10555	COG4844	belongs to the
NZD48_RS10560	COG0471	metal ion transport
NZD48_RS10575	COG0531	amino acid
NZD48_RS10585	COG0280	phosphate acetyltransferase
NZD48_RS10590	COG0095	Lipoate-protein ligase
NZD48_RS10595	COG2814	Major facilitator Superfamily
NZD48_RS10600	COG1566	PFAM secretion protein HlyD family protein
NZD48_RS10615	COG0531	amino acid
NZD48_RS10620	COG2363	Small membrane protein
NZD48_RS10630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NZD48_RS10705	COG0702	epimerase
NZD48_RS10730	COG0640	Transcriptional regulator
NZD48_RS10750	COG3682	Transcriptional regulator
NZD48_RS10780	COG1192	Involved in chromosome partitioning
NZD48_RS10805	COG0551	DNA topoisomerase type I activity
NZD48_RS10805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NZD48_RS10815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NZD48_RS10825	COG2226	methyltransferase
NZD48_RS10895	COG0318	PFAM AMP-dependent synthetase and ligase
NZD48_RS10905	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NZD48_RS10925	COG1737	Transcriptional regulator
NZD48_RS10935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NZD48_RS10945	COG0431	NADPH-dependent FMN reductase
NZD48_RS10950	COG0561	phosphatase activity
NZD48_RS10960	COG1428	Deoxynucleoside kinase
NZD48_RS10965	COG1428	Deoxynucleoside kinase
NZD48_RS10990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NZD48_RS11000	COG1473	amidohydrolase
NZD48_RS11015	COG0049	tRNA binding
NZD48_RS11020	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NZD48_RS11030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NZD48_RS11040	COG2813	Specifically methylates the guanine in position
NZD48_RS11050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NZD48_RS11055	COG0081	regulation of translation
NZD48_RS11060	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NZD48_RS11065	COG0250	Participates in transcription elongation, termination and antitermination
NZD48_RS11070	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NZD48_RS11075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NZD48_RS11090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NZD48_RS11095	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NZD48_RS11100	COG0215	cysteine-tRNA ligase activity
NZD48_RS11125	COG4956	integral membrane protein (PIN domain superfamily)
NZD48_RS11130	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NZD48_RS11140	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NZD48_RS11155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NZD48_RS11160	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NZD48_RS11165	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NZD48_RS11170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NZD48_RS11265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NZD48_RS11270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NZD48_RS11290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NZD48_RS11295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NZD48_RS11310	COG1098	S1 RNA binding domain
NZD48_RS11320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NZD48_RS11325	COG3956	TIGRFAM MazG family protein
NZD48_RS11330	COG2244	polysaccharide biosynthetic process
NZD48_RS11335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NZD48_RS11340	COG0193	aminoacyl-tRNA hydrolase activity
NZD48_RS11350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NZD48_RS11355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NZD48_RS11360	COG2088	sporulation resulting in formation of a cellular spore
NZD48_RS11365	COG0251	oxidation-reduction process
NZD48_RS11370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NZD48_RS11375	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NZD48_RS11380	COG4466	Protein conserved in bacteria
NZD48_RS11385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NZD48_RS11390	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NZD48_RS11395	COG0084	hydrolase, TatD family'
NZD48_RS11405	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NZD48_RS11410	COG2827	Endonuclease containing a URI domain
NZD48_RS11415	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NZD48_RS11425	COG1774	PSP1 C-terminal conserved region
NZD48_RS11430	COG0470	DNA polymerase III
NZD48_RS11435	COG3870	Protein conserved in bacteria
NZD48_RS11440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NZD48_RS11445	COG1982	Orn Lys Arg decarboxylase major
NZD48_RS11470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NZD48_RS11475	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NZD48_RS11480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NZD48_RS11495	COG2188	Transcriptional regulator
NZD48_RS11500	COG0366	Alpha amylase catalytic
NZD48_RS11505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NZD48_RS11505	COG1263	PTS System
NZD48_RS11515	COG0493	'glutamate synthase
NZD48_RS11520	COG0067	glutamate synthase
NZD48_RS11520	COG0069	glutamate synthase activity
NZD48_RS11520	COG0070	glutamate synthase
NZD48_RS11525	COG0583	DNA-binding transcription factor activity
NZD48_RS11540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NZD48_RS11560	COG0626	cystathionine gamma-synthase activity
NZD48_RS11565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NZD48_RS11575	COG2272	Belongs to the type-B carboxylesterase lipase family
NZD48_RS11600	COG0733	neurotransmitter:sodium symporter activity
NZD48_RS11605	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NZD48_RS11610	COG0574	Belongs to the PEP-utilizing enzyme family
NZD48_RS11610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NZD48_RS11700	COG1388	LysM domain
NZD48_RS11700	COG3942	CHAP domain
NZD48_RS11735	COG2076	Multidrug Resistance protein
NZD48_RS11740	COG2076	Multidrug Resistance protein
NZD48_RS11755	COG1124	(ABC) transporter
NZD48_RS11760	COG0444	Belongs to the ABC transporter superfamily
NZD48_RS11765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NZD48_RS11770	COG0601	transmembrane transport
NZD48_RS11775	COG0747	negative chemotaxis
NZD48_RS11805	COG1011	Hydrolase
NZD48_RS11830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NZD48_RS11845	COG2832	Protein of unknown function (DUF454)
NZD48_RS11850	COG5492	domain, Protein
NZD48_RS11865	COG1609	Transcriptional regulator
NZD48_RS11890	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NZD48_RS11910	COG3728	DNA packaging
NZD48_RS11910	COG5484	DNA packaging
NZD48_RS11945	COG0640	Transcriptional regulator
NZD48_RS11965	COG3093	addiction module antidote protein HigA
NZD48_RS11980	COG1388	LysM domain
NZD48_RS12085	COG0582	viral genome integration into host DNA
NZD48_RS12090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NZD48_RS12090	COG0519	Catalyzes the synthesis of GMP from XMP
NZD48_RS12095	COG0516	GMP reductase activity
NZD48_RS12095	COG0517	IMP dehydrogenase activity
NZD48_RS12100	COG2233	PERMEase
NZD48_RS12105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NZD48_RS12125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NZD48_RS12130	COG1823	symporter activity
NZD48_RS12135	COG0778	Nitroreductase
NZD48_RS12145	COG0450	alkyl hydroperoxide reductase
NZD48_RS12150	COG3634	alkyl hydroperoxide reductase activity
NZD48_RS12195	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NZD48_RS12205	COG0360	Binds together with S18 to 16S ribosomal RNA
NZD48_RS12210	COG2910	NAD(P)H-binding
NZD48_RS12215	COG0012	GTP binding
NZD48_RS12220	COG4481	Protein conserved in bacteria
NZD48_RS12225	COG0668	transmembrane transport
NZD48_RS12230	COG1475	DNA binding
NZD48_RS12235	COG0626	cystathionine gamma-synthase activity
NZD48_RS12240	COG0626	cystathionine gamma-synthase activity
NZD48_RS12245	COG0646	methionine synthase
NZD48_RS12245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NZD48_RS12270	COG1279	arginine transmembrane transporter activity
NZD48_RS12285	COG0829	nickel cation binding
NZD48_RS12290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NZD48_RS12295	COG0830	nickel cation binding
NZD48_RS12300	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NZD48_RS12305	COG2353	YceI-like domain
NZD48_RS12310	COG1846	Transcriptional regulator
NZD48_RS12340	COG1388	LysM domain
NZD48_RS12350	COG0357	Ribosomal RNA small subunit methyltransferase G
NZD48_RS12360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NZD48_RS12365	COG0594	ribonuclease P activity