locus-tag	class	description
H3V22_RS00015	ENOG4105ZPI	UPF0358 protein
H3V22_RS00020	ENOG4105CNI	cell division protein FtsW
H3V22_RS00035	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
H3V22_RS00040	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
H3V22_RS00075	ENOG4108REF	Sporulation integral membrane protein ytvi
H3V22_RS00085	ENOG4106UY4	Inherit from COG: Scp-like extracellular
H3V22_RS00100	ENOG4105WUC	UPF0298 protein
H3V22_RS00110	ENOG4106H78	methyltransferase
H3V22_RS00115	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
H3V22_RS00130	ENOG41067VY	50S ribosomal protein L32
H3V22_RS00135	ENOG4108RWN	rrna methyltransferase
H3V22_RS00140	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
H3V22_RS00145	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
H3V22_RS00150	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H3V22_RS00165	ENOG4105DCG	PHP domain protein
H3V22_RS00170	ENOG4105C98	muts2 protein
H3V22_RS00175	ENOG41060WC	Enoyl-CoA hydratase
H3V22_RS00180	ENOG4105K63	Thioredoxin
H3V22_RS00185	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
H3V22_RS00190	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
H3V22_RS00200	ENOG4105E33	succinate dehydrogenase
H3V22_RS00205	ENOG41067TZ	transcriptional regulator, MarR family
H3V22_RS00210	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
H3V22_RS00245	ENOG4105CM2	brancheD-chain amino acid aminotransferase
H3V22_RS00255	ENOG4108YG3	N-acetyltransferase
H3V22_RS00260	ENOG41074B2	UPF0747 protein
H3V22_RS00265	ENOG4108V6E	Cell division protein mraZ
H3V22_RS00270	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
H3V22_RS00275	ENOG41068DC	Essential cell division protein (By similarity)
H3V22_RS00280	ENOG4105CJN	penicillin-binding protein
H3V22_RS00285	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
H3V22_RS00295	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
H3V22_RS00300	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
H3V22_RS00305	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
H3V22_RS00310	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
H3V22_RS00315	ENOG4105DFA	alanine racemase domain protein
H3V22_RS00320	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
H3V22_RS00325	ENOG41067XK	integral membrane protein
H3V22_RS00330	ENOG4105DBK	s4 domain protein
H3V22_RS00340	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
H3V22_RS00350	ENOG4105C34	Pseudouridine synthase
H3V22_RS00355	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
H3V22_RS00365	ENOG4105CXT	aspartate transcarbamylase
H3V22_RS00375	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
H3V22_RS00380	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
H3V22_RS00385	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
H3V22_RS00390	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
H3V22_RS00395	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
H3V22_RS00400	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
H3V22_RS00410	ENOG4105C8P	)-transporter
H3V22_RS00425	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
H3V22_RS00430	ENOG41067UH	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
H3V22_RS00435	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
H3V22_RS00440	ENOG4105C25	Primosomal protein n'
H3V22_RS00450	ENOG4105NQN	cytochrome C
H3V22_RS00455	ENOG4105CNI	cell division protein FtsW
H3V22_RS00460	ENOG4108KGH	TRANSCRIPTIONal
H3V22_RS00465	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H3V22_RS00470	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
H3V22_RS00475	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H3V22_RS00480	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
H3V22_RS00505	ENOG4105EFI	regulatoR
H3V22_RS00510	ENOG4105BZU	Histidine kinase
H3V22_RS00515	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
H3V22_RS00520	ENOG4105DJV	ribulose-phosphate 3-epimerase
H3V22_RS00525	ENOG4105FJ0	thiamine
H3V22_RS00530	ENOG4105VB9	50S ribosomal protein l28
H3V22_RS00535	ENOG4108ZAA	Alkaline-shock protein
H3V22_RS00550	ENOG4105EJQ	L-serine dehydratase
H3V22_RS00555	ENOG4105CB5	ATP-dependent DNA helicase recG
H3V22_RS00560	ENOG4108Z6X	(sortase) family
H3V22_RS00565	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
H3V22_RS00570	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
H3V22_RS00580	ENOG4105CHR	reductase
H3V22_RS00585	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
H3V22_RS00590	ENOG41068KG	domain protein
H3V22_RS00600	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
H3V22_RS00605	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
H3V22_RS00620	ENOG4105K5M	30s ribosomal protein S16
H3V22_RS00625	ENOG4105VB6	UPF0109 protein
H3V22_RS00630	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
H3V22_RS00635	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
H3V22_RS00640	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
H3V22_RS00645	ENOG4105EJV	Membrane
H3V22_RS00650	ENOG4105EJV	Membrane
H3V22_RS00655	ENOG4105CKK	Glycosyl transferase, family 2
H3V22_RS00660	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
H3V22_RS00665	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H3V22_RS00670	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
H3V22_RS00675	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
H3V22_RS00685	ENOG4105C79	DNA protecting protein DprA
H3V22_RS00690	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
H3V22_RS00695	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
H3V22_RS00700	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H3V22_RS00705	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
H3V22_RS00710	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
H3V22_RS00715	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
H3V22_RS00720	ENOG4105CE9	30S ribosomal protein S2
H3V22_RS00725	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
H3V22_RS00730	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
H3V22_RS00735	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
H3V22_RS00745	ENOG4105KNE	Phosphatidate cytidylyltransferase
H3V22_RS00750	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
H3V22_RS00755	ENOG4105DZP	Membrane-associated zinc metalloprotease
H3V22_RS00760	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
H3V22_RS00770	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
H3V22_RS00775	ENOG4105CHV	Transcription elongation factor NusA
H3V22_RS00780	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
H3V22_RS00785	ENOG4105VHM	ribosomal protein
H3V22_RS00790	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
H3V22_RS00795	ENOG4107R5R	arsenical pump membrane protein
H3V22_RS00820	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
H3V22_RS00825	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
H3V22_RS00830	ENOG4105CI1	PTS System
H3V22_RS00835	ENOG4105C87	Aminotransferase class I and II
H3V22_RS00840	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
H3V22_RS00850	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
H3V22_RS00855	ENOG4105BZW	Glycerate kinase
H3V22_RS00865	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H3V22_RS00870	ENOG41062D9	Histidine kinase
H3V22_RS00880	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
H3V22_RS00885	ENOG4105DTN	riboflavin biosynthesis protein ribF
H3V22_RS00895	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
H3V22_RS00900	ENOG4105C1V	Peptidase, M16
H3V22_RS00905	ENOG4105CN5	Metallo-Beta-Lactamase
H3V22_RS00910	ENOG4105CNU	cell division protein FtsK
H3V22_RS00915	ENOG4105FDP	GntR family transcriptional regulator
H3V22_RS00930	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
H3V22_RS00945	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
H3V22_RS00950	ENOG4105CEV	competence damage-inducible protein
H3V22_RS00955	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
H3V22_RS00960	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
H3V22_RS01070	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
H3V22_RS01105	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
H3V22_RS01140	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
H3V22_RS01150	ENOG4105D48	metallophosphoesterase
H3V22_RS01155	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
H3V22_RS01160	ENOG4105DQU	oxidoreductase, subunit beta
H3V22_RS01170	ENOG4105BZ1	(ABC) transporter
H3V22_RS01175	ENOG4105BZ1	(ABC) transporter
H3V22_RS01185	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
H3V22_RS01195	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
H3V22_RS01200	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
H3V22_RS01205	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
H3V22_RS01215	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
H3V22_RS01220	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
H3V22_RS01230	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
H3V22_RS01235	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
H3V22_RS01240	ENOG4108V06	Glutathione peroxidase
H3V22_RS01245	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H3V22_RS01250	ENOG4105CXI	aluminum resistance protein
H3V22_RS01255	ENOG4105KV4	Transcriptional regulator
H3V22_RS01260	ENOG4105C5F	glutamine synthetase
H3V22_RS01280	ENOG4105D5G	Transposase
H3V22_RS01290	ENOG4108Z7F	N-acetyltransferase
H3V22_RS01330	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
H3V22_RS01345	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
H3V22_RS01360	ENOG4105CFH	Aspartokinase
H3V22_RS01365	ENOG4105D6E	homoserine dehydrogenase
H3V22_RS01370	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
H3V22_RS01375	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
H3V22_RS01380	ENOG410667J	hydrolase
H3V22_RS01395	ENOG4108IQI	permease
H3V22_RS01400	ENOG4105WDJ	50S ribosomal protein L33
H3V22_RS01410	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
H3V22_RS01430	ENOG4105VPS	UPF0291 protein
H3V22_RS01435	ENOG4105CV1	Transketolase (EC 2.2.1.1)
H3V22_RS01440	ENOG4105VXM	UPF0154 protein
H3V22_RS01445	ENOG4107QIV	Cytochrome c biogenesis protein
H3V22_RS01470	ENOG4108KF3	Electron transport protein SCO1 SenC
H3V22_RS01475	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
H3V22_RS01480	ENOG4105C94	Transporter
H3V22_RS01485	ENOG4108I0Z	Aconitate hydratase
H3V22_RS01500	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
H3V22_RS01510	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3V22_RS01525	ENOG4105CID	antiterminator
H3V22_RS01530	ENOG4105CI1	PTS System
H3V22_RS01545	ENOG4107T5V	SNARE associated Golgi
H3V22_RS01550	ENOG4108FKN	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
H3V22_RS01555	ENOG4108RCF	TRANSCRIPTIONal
H3V22_RS01570	ENOG4105DWT	malate dehydrogenase (quinone)
H3V22_RS01580	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
H3V22_RS01605	ENOG4105BZW	Glycerate kinase
H3V22_RS01610	ENOG4105VZ8	Transcriptional regulator
H3V22_RS01625	ENOG4105EVN	Prephenate dehydrogenase
H3V22_RS01630	ENOG4105DER	m42 family
H3V22_RS01635	ENOG4105CRQ	synthase (Component I)
H3V22_RS01640	ENOG4105DDQ	anthranilate synthase
H3V22_RS01645	ENOG4108I0Q	anthranilate phosphoribosyltransferase
H3V22_RS01650	ENOG4105DK0	Indole-3-glycerol phosphate synthase
H3V22_RS01655	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
H3V22_RS01660	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
H3V22_RS01665	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
H3V22_RS01675	ENOG4108RMH	femAB family
H3V22_RS01690	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
H3V22_RS01720	ENOG4108BUD	transposase
H3V22_RS01730	ENOG4105FFM	Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity)
H3V22_RS01755	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
H3V22_RS01840	ENOG4105CAY	ferredoxin--nadp reductase
H3V22_RS01845	ENOG41085FC	arsR family transcriptional regulator
H3V22_RS01865	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
H3V22_RS01875	ENOG4107R5R	arsenical pump membrane protein
H3V22_RS01900	ENOG4107RBB	ABC transporter, permease
H3V22_RS01905	ENOG4105C19	ABC transporter
H3V22_RS01920	ENOG4107TXC	Transcriptional regulator
H3V22_RS01940	ENOG4105QNR	S1 RNA binding domain protein
H3V22_RS01945	ENOG4105C5H	ABC transporter
H3V22_RS01950	ENOG4105CFH	Aspartokinase
H3V22_RS01955	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
H3V22_RS01960	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H3V22_RS01965	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
H3V22_RS01975	ENOG4105CH2	amidohydrolase
H3V22_RS01980	ENOG4108XFP	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
H3V22_RS01985	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
H3V22_RS02000	ENOG410855V	Acylphosphatase
H3V22_RS02010	ENOG4105CDW	Resistance protein
H3V22_RS02015	ENOG4105JHY	Membrane
H3V22_RS02020	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
H3V22_RS02025	ENOG4107T89	von Willebrand factor, type A
H3V22_RS02030	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
H3V22_RS02045	ENOG4105C7S	Dehydrogenase
H3V22_RS02050	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
H3V22_RS02055	ENOG4105GR3	Histidine kinase
H3V22_RS02060	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H3V22_RS02065	ENOG410841Q	phosphoesterase PA-phosphatase related protein
H3V22_RS02090	ENOG4105C5Y	PTS System
H3V22_RS02095	ENOG4105E0X	reductase
H3V22_RS02120	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
H3V22_RS02135	ENOG4108Y6J	UPF0403 protein
H3V22_RS02140	ENOG4106QQ5	PBS lyase HEAT domain protein repeat-containing protein
H3V22_RS02170	ENOG410890F	Dynamin family
H3V22_RS02185	ENOG4107RQ2	Cytochrome c oxidase, subunit I
H3V22_RS02195	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
H3V22_RS02205	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
H3V22_RS02210	ENOG4108UKS	UPF0398 protein
H3V22_RS02225	ENOG4105BZ4	penicillin-binding protein
H3V22_RS02235	ENOG4105CSM	endonuclease III
H3V22_RS02260	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
H3V22_RS02265	ENOG4105CPK	Glycosyl transferase (Group 1
H3V22_RS02270	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
H3V22_RS02285	ENOG4105PE6	Menaquinol-cytochrome c reductase, cytochrome b c subunit
H3V22_RS02290	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H3V22_RS02310	ENOG41068YB	TPR repeat-containing protein
H3V22_RS02315	ENOG4105D49	3-dehydroquinate synthase
H3V22_RS02325	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
H3V22_RS02330	ENOG4105EAH	synthase
H3V22_RS02335	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H3V22_RS02345	ENOG4105K70	DNA-binding protein
H3V22_RS02360	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
H3V22_RS02365	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
H3V22_RS02370	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
H3V22_RS02375	ENOG4105CAT	Cytidine monophosphate kinase
H3V22_RS02380	ENOG4107RB3	L-asparaginase
H3V22_RS02385	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
H3V22_RS02400	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H3V22_RS02405	ENOG4105T7X	
H3V22_RS02420	ENOG4105BZU	Histidine kinase
H3V22_RS02425	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H3V22_RS02430	ENOG4105CRE	cytochrome C
H3V22_RS02435	ENOG4107TWT	Cytochrome c biogenesis protein
H3V22_RS02440	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3V22_RS02445	ENOG4105FE9	pseudouridine synthase
H3V22_RS02450	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
H3V22_RS02455	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
H3V22_RS02465	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H3V22_RS02470	ENOG4105I3K	Ferric uptake regulator, Fur family
H3V22_RS02475	ENOG4108YZ4	nudix hydrolase
H3V22_RS02480	ENOG4105CPC	Aldo Keto reductase
H3V22_RS02490	ENOG4105II7	pyrroline-5-carboxylate reductase
H3V22_RS02500	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
H3V22_RS02515	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
H3V22_RS02525	ENOG4108QEG	Membrane
H3V22_RS02530	ENOG4108Y6J	UPF0403 protein
H3V22_RS02535	ENOG4105C7S	Dehydrogenase
H3V22_RS02540	ENOG4105CPP	Dehydrogenase, E1 component
H3V22_RS02555	ENOG4105CKM	Branched-chain carboxylic acid kinase
H3V22_RS02570	ENOG4106CCJ	Protein of unknown function (DUF2627)
H3V22_RS02580	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
H3V22_RS02585	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
H3V22_RS02590	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
H3V22_RS02605	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H3V22_RS02610	ENOG4105M7K	Involved in the transcription termination process (By similarity)
H3V22_RS02615	ENOG4108ZSR	alkaline shock protein
H3V22_RS02620	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H3V22_RS02630	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
H3V22_RS02635	ENOG4105DC7	peptidase M24
H3V22_RS02650	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
H3V22_RS02655	ENOG4105WZW	rhodanese family
H3V22_RS02660	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H3V22_RS02665	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H3V22_RS02670	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
H3V22_RS02680	ENOG4105D5G	Transposase
H3V22_RS02725	ENOG4105C5X	domain protein
H3V22_RS02750	ENOG4107ZXI	Rhomboid family
H3V22_RS02755	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
H3V22_RS02760	ENOG4105WDJ	50S ribosomal protein L33
H3V22_RS02770	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H3V22_RS02775	ENOG4105E2Z	phosphate ABC transporter (Permease
H3V22_RS02780	ENOG4105C8U	phosphate abc transporter
H3V22_RS02785	ENOG4105CVA	phosphate
H3V22_RS02795	ENOG4107RF6	penicillin-binding protein
H3V22_RS02800	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
H3V22_RS02810	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
H3V22_RS02815	ENOG4108U5J	'-nucleotidase
H3V22_RS02820	ENOG4105N80	Ferric uptake regulator, Fur family
H3V22_RS02825	ENOG4105FAV	ABC, transporter
H3V22_RS02830	ENOG4105FDK	ABC transporter
H3V22_RS02835	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
H3V22_RS02840	ENOG4105C1J	atp-dependent rna helicase
H3V22_RS02845	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
H3V22_RS02865	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3V22_RS02870	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H3V22_RS02875	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
H3V22_RS02885	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
H3V22_RS02890	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
H3V22_RS02900	ENOG4105KG3	cytidine deaminase
H3V22_RS02910	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
H3V22_RS02915	ENOG4105C9A	Phoh family
H3V22_RS02930	ENOG4105DI5	UPF0365 protein
H3V22_RS02935	ENOG4105F7J	membrane-bound serine protease
H3V22_RS02940	ENOG4105VCC	30S ribosomal protein S21
H3V22_RS02945	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
H3V22_RS02950	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
H3V22_RS02955	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
H3V22_RS02965	ENOG4105CFG	Acts as a chaperone (By similarity)
H3V22_RS02970	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H3V22_RS02980	ENOG4105CSA	Coproporphyrinogen iii oxidase
H3V22_RS02985	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
H3V22_RS02990	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
H3V22_RS02995	ENOG4105TQK	DNA polymerase iii, delta' subunit
H3V22_RS03010	ENOG4108UK2	deaminase
H3V22_RS03015	ENOG4105KQC	Competence protein
H3V22_RS03020	ENOG4105DXX	methyltransferase
H3V22_RS03030	ENOG4108WF2	Metal Dependent Phosphohydrolase
H3V22_RS03035	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H3V22_RS03040	ENOG410812S	Rna-binding protein
H3V22_RS03045	ENOG4105E2X	shikimate dehydrogenase
H3V22_RS03050	ENOG4105CQW	ribosome biogenesis GTPase YqeH
H3V22_RS03055	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
H3V22_RS03060	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
H3V22_RS03065	ENOG4105C5A	transporter
H3V22_RS03075	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H3V22_RS03080	ENOG4105C7S	Dehydrogenase
H3V22_RS03090	ENOG4105P4J	Allophanate hydrolase, subunit 1
H3V22_RS03100	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
H3V22_RS03105	ENOG4105DBI	uridine monophosphokinase
H3V22_RS03110	ENOG4105CFP	Peptidase U32
H3V22_RS03115	ENOG4105XYU	peptidase (U32 family)
H3V22_RS03125	ENOG4105HHA	aminodeoxychorismate lyase
H3V22_RS03135	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
H3V22_RS03140	ENOG4105VBH	UPF0297 protein
H3V22_RS03145	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
H3V22_RS03150	ENOG4105C7H	Helicase, RecD TraA family
H3V22_RS03160	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
H3V22_RS03165	ENOG4105C3J	Cysteine desulfurase
H3V22_RS03170	ENOG4105C5H	ABC transporter
H3V22_RS03175	ENOG4105DEN	Luciferase family
H3V22_RS03180	ENOG4108CHM	Preferentially cleaves peptide bonds on the carboxyl- terminal side of aspartate and glutamate. Along with other extracellular proteases it is involved in colonization and infection of human tissues. Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB. It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells. May also protect bacteria against host defense mechanism by cleaving the immunoglobulin classes IgG, IgA and IgM. May be involved in the stability of secreted lipases
H3V22_RS03190	ENOG4105D1H	recombination factor protein RarA
H3V22_RS03195	ENOG4105D5G	Transposase
H3V22_RS03200	ENOG4105CUZ	uba thif-type nad fad binding protein
H3V22_RS03210	ENOG4105C9M	aspartyl-trna synthetase
H3V22_RS03215	ENOG4105CUT	histidyl-tRNA synthetase
H3V22_RS03220	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
H3V22_RS03230	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H3V22_RS03235	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
H3V22_RS03240	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
H3V22_RS03245	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H3V22_RS03250	ENOG4105VIE	preprotein translocase, subunit YajC
H3V22_RS03255	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
H3V22_RS03260	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
H3V22_RS03265	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
H3V22_RS03270	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
H3V22_RS03275	ENOG41090I5	UPF0735 ACT domain-containing protein
H3V22_RS03280	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H3V22_RS03290	ENOG4105K46	50S ribosomal protein l27
H3V22_RS03295	ENOG4105X36	(ribosomal) protein
H3V22_RS03300	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
H3V22_RS03310	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
H3V22_RS03335	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H3V22_RS03340	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
H3V22_RS03345	ENOG4105ZX1	Transposase C
H3V22_RS03350	ENOG4108KU9	integrase family
H3V22_RS03355	ENOG4108FPN	Integrase
H3V22_RS03375	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H3V22_RS03390	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
H3V22_RS03395	ENOG4105D52	delta-aminolevulinic acid dehydratase
H3V22_RS03405	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
H3V22_RS03415	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
H3V22_RS03420	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
H3V22_RS03425	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
H3V22_RS03430	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
H3V22_RS03440	ENOG4105U6W	MutT NUDIX family protein
H3V22_RS03445	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
H3V22_RS03450	ENOG4105VJV	50s ribosomal protein L35
H3V22_RS03455	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
H3V22_RS03460	ENOG4108IQI	permease
H3V22_RS03485	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
H3V22_RS03490	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
H3V22_RS03500	ENOG4105C2M	dna polymerase I
H3V22_RS03505	ENOG4105BZU	Histidine kinase
H3V22_RS03510	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
H3V22_RS03520	ENOG4108HMX	isocitrate dehydrogenase (NADP)
H3V22_RS03525	ENOG4105BZN	citrate synthase
H3V22_RS03530	ENOG4105C85	amino acid
H3V22_RS03535	ENOG4105CA9	Pyruvate kinase
H3V22_RS03540	ENOG4105CTQ	phosphohexokinase
H3V22_RS03545	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
H3V22_RS03550	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
H3V22_RS03555	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
H3V22_RS03560	ENOG4105C6K	Malic enzyme
H3V22_RS03565	ENOG4105C0B	DNA polymerase III (alpha subunit)
H3V22_RS03570	ENOG4105SFS	phosphoesterase RecJ domain protein
H3V22_RS03590	ENOG4105DC7	peptidase M24
H3V22_RS03595	ENOG4106N3A	copper homeostasis protein cutc
H3V22_RS03600	ENOG4105DCF	alanine dehydrogenase
H3V22_RS03605	ENOG4107YZX	Universal stress protein
H3V22_RS03610	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
H3V22_RS03620	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
H3V22_RS03625	ENOG4105VK3	rdd domain containing protein
H3V22_RS03630	ENOG4105D07	Signal peptide peptidase, SppA
H3V22_RS03645	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
H3V22_RS03655	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
H3V22_RS03665	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
H3V22_RS03670	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
H3V22_RS03675	ENOG4108X3M	OsmC Ohr family protein
H3V22_RS03685	ENOG4108JQ1	Dehydrogenase
H3V22_RS03695	ENOG4105F6E	Acyl-transferase
H3V22_RS03700	ENOG4105C0H	protease
H3V22_RS03710	ENOG4108V0P	LemA family
H3V22_RS03715	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
H3V22_RS03720	ENOG4105BZ4	penicillin-binding protein
H3V22_RS03725	ENOG4105CKU	formyltetrahydrofolate synthetase
H3V22_RS03735	ENOG4105F1V	Acetoin utilization protein
H3V22_RS03740	ENOG4105W87	Cbs domain
H3V22_RS03755	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
H3V22_RS03765	ENOG4105MQN	general stress protein
H3V22_RS03770	ENOG4105DFU	Cell wall formation (By similarity)
H3V22_RS03780	ENOG4108VDD	TRNA binding domain protein
H3V22_RS03785	ENOG4108NKM	UPF0354 protein
H3V22_RS03810	ENOG4105C87	Aminotransferase class I and II
H3V22_RS03815	ENOG4105C8F	Beta-lactamase domain protein
H3V22_RS03825	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
H3V22_RS03830	ENOG4108V15	phosphotransferase enzyme family
H3V22_RS03835	ENOG4105F0I	Aminotransferase
H3V22_RS03860	ENOG4105CBX	hi0933 family
H3V22_RS03865	ENOG41085GJ	domain protein
H3V22_RS03870	ENOG4105C8T	Leucyl-tRNA synthetase
H3V22_RS03875	ENOG410605W	Major Facilitator
H3V22_RS03880	ENOG4105N5T	Radical SAM Protein
H3V22_RS03895	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
H3V22_RS03900	ENOG4108Z0R	Transferase
H3V22_RS03920	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
H3V22_RS03925	ENOG4108R6K	riboflavin synthase, subunit alpha
H3V22_RS03930	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
H3V22_RS03955	ENOG4105R40	Glycine betaine carnitine choline
H3V22_RS03995	ENOG4107YBY	Hydrolase
H3V22_RS04015	ENOG4108UW5	maltose o-acetyltransferase
H3V22_RS04025	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
H3V22_RS04040	ENOG4105WMR	Protein CrcB homolog
H3V22_RS04045	ENOG4106A8V	Protein CrcB homolog
H3V22_RS04055	ENOG4105C26	Dehydrogenase
H3V22_RS04065	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
H3V22_RS04070	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
H3V22_RS04080	ENOG4105M6F	mutator MutT protein
H3V22_RS04090	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
H3V22_RS04100	ENOG4105CEY	Amp-dependent synthetase and ligase
H3V22_RS04110	ENOG4105F27	Major Facilitator
H3V22_RS04120	ENOG4105DQ6	Transposase
H3V22_RS04130	ENOG4105D5G	Transposase
H3V22_RS04135	ENOG4105D5G	Transposase
H3V22_RS04140	ENOG4108V5C	ABC transporter
H3V22_RS04205	ENOG4105D5G	Transposase
H3V22_RS04220	ENOG4105C1Q	protoporphyrinogen oxidase
H3V22_RS04225	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
H3V22_RS04230	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
H3V22_RS04235	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
H3V22_RS04250	ENOG4105K59	histidine triad (HIT) protein
H3V22_RS04260	ENOG41088ZC	Negative regulator of protease production and sporulation (By similarity)
H3V22_RS04270	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
H3V22_RS04275	ENOG4105EQI	Metal Dependent Phosphohydrolase
H3V22_RS04285	ENOG4107VRP	DNA repair exonuclease
H3V22_RS04290	ENOG4105WZB	UPF0342 protein
H3V22_RS04295	ENOG4108UH6	UPF0754 membrane protein
H3V22_RS04310	ENOG4105WH1	Two component transcriptional regulator luxr family
H3V22_RS04315	ENOG4105BZU	Histidine kinase
H3V22_RS04320	ENOG4108YBP	pseudouridine synthase
H3V22_RS04325	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
H3V22_RS04335	ENOG4105C9Q	fumarate hydratase class II
H3V22_RS04340	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
H3V22_RS04345	ENOG4105CE4	GlcNAc 6-P deacetylase
H3V22_RS04355	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
H3V22_RS04360	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
H3V22_RS04365	ENOG4105CAS	nag kinase
H3V22_RS04370	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
H3V22_RS04375	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
H3V22_RS04380	ENOG4105CDA	abc transporter atp-binding protein
H3V22_RS04385	ENOG4105E5Q	amino acid AbC transporter
H3V22_RS04390	ENOG4105C5I	Dehydrogenase
H3V22_RS04540	ENOG4105TUA	UPF0295 protein
H3V22_RS04550	ENOG4105G5W	regulator Fur family
H3V22_RS04555	ENOG4105C5I	Dehydrogenase
H3V22_RS04560	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3V22_RS04565	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
H3V22_RS04570	ENOG4107NBY	Membrane
H3V22_RS04580	ENOG4105CBC	glutamate synthase
H3V22_RS04590	ENOG4105EVI	UPF0374 protein
H3V22_RS04595	ENOG4105CEN	a g-specific adenine glycosylase
H3V22_RS04600	ENOG41067AE	Membrane-bound metal-dependent hydrolase
H3V22_RS04610	ENOG4105EY8	ABC transporter
H3V22_RS04620	ENOG410902V	Modulates RecA activity (By similarity)
H3V22_RS04625	ENOG4105BZ4	penicillin-binding protein
H3V22_RS04635	ENOG4108Z0Z	intracellular protease Pfpi family
H3V22_RS04650	ENOG4108S4H	thioesterase Superfamily protein
H3V22_RS04670	ENOG4105KWG	Pfam:DUF1696
H3V22_RS04680	ENOG4107U9T	Pfam:Ribonuclease_BN
H3V22_RS04685	ENOG4108V2W	Carbonate dehydratase
H3V22_RS04690	ENOG4105WH1	Two component transcriptional regulator luxr family
H3V22_RS04695	ENOG4105ENE	Histidine kinase
H3V22_RS04710	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
H3V22_RS04715	ENOG4108V3A	UPF0421 protein
H3V22_RS04730	ENOG41090A1	ferritin
H3V22_RS04745	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
H3V22_RS04755	ENOG4105D8V	Glucose sorbosone dehydrogenase
H3V22_RS04795	ENOG4105CBD	Diacylglycerol kinase
H3V22_RS04800	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H3V22_RS04805	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H3V22_RS04815	ENOG4105CK7	Sodium proline symporter
H3V22_RS04820	ENOG4105CK7	Sodium proline symporter
H3V22_RS04830	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
H3V22_RS04835	ENOG4105C4R	Atp-dependent dna helicase
H3V22_RS04840	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
H3V22_RS04845	ENOG4108VXD	carboxy-peptidase
H3V22_RS04850	ENOG4105KGF	protein, YerC YecD
H3V22_RS04855	ENOG4105C83	adenylosuccinate lyase
H3V22_RS04865	ENOG4108U5N	UPF0316 protein
H3V22_RS04870	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
H3V22_RS04875	ENOG4105DAP	Nicotinate phosphoribosyltransferase
H3V22_RS04880	ENOG4108ISG	Major Facilitator
H3V22_RS04890	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
H3V22_RS04895	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
H3V22_RS04900	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H3V22_RS04905	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
H3V22_RS04910	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
H3V22_RS04915	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
H3V22_RS04920	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
H3V22_RS04925	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
H3V22_RS04935	ENOG4105CQC	Prephenate dehydratase
H3V22_RS04950	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
H3V22_RS04965	ENOG4105EE0	oxidoreductase
H3V22_RS04970	ENOG4105C26	Dehydrogenase
H3V22_RS04975	ENOG4105C4B	ABC transporter, permease
H3V22_RS04980	ENOG4108IXI	(ABC) transporter
H3V22_RS04985	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
H3V22_RS04990	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
H3V22_RS04995	ENOG410695V	Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP (By similarity)
H3V22_RS05030	ENOG4105C09	Bile acid
H3V22_RS05050	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
H3V22_RS05060	ENOG4105C6Z	Gluconate
H3V22_RS05065	ENOG4105CMG	Carbohydrate kinase
H3V22_RS05070	ENOG4105G3Z	GntR family transcriptional regulator
H3V22_RS05090	ENOG4105CJ1	ABC, transporter
H3V22_RS05105	ENOG4105CIG	ABC transporter
H3V22_RS05125	ENOG4105D01	(LipO)protein
H3V22_RS05130	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
H3V22_RS05140	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
H3V22_RS05180	ENOG4105CUC	YeeE YedE family protein
H3V22_RS05185	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
H3V22_RS05190	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
H3V22_RS05195	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
H3V22_RS05200	ENOG4105C5H	ABC transporter
H3V22_RS05210	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H3V22_RS05215	ENOG410801F	ribosomal-protein-alanine acetyltransferase
H3V22_RS05220	ENOG41072GX	Peptidase M22 Glycoprotease
H3V22_RS05225	ENOG4105K8N	protein family UPF0079, ATPase
H3V22_RS05230	ENOG4105C01	Dihydroxy-acid dehydratase
H3V22_RS05235	ENOG4105C7K	acetolactate synthase
H3V22_RS05245	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
H3V22_RS05250	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
H3V22_RS05255	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H3V22_RS05260	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H3V22_RS05270	ENOG4105C7B	Threonine dehydratase
H3V22_RS05300	ENOG410906U	SprT-like
H3V22_RS05315	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
H3V22_RS05320	ENOG4105WN5	stage II sporulation protein
H3V22_RS05325	ENOG4107SGM	protein serine threonine phosphatase
H3V22_RS05340	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
H3V22_RS05350	ENOG410905X	membrane-flanked domain protein
H3V22_RS05360	ENOG410905X	membrane-flanked domain protein
H3V22_RS05365	ENOG4105C1J	atp-dependent rna helicase
H3V22_RS05375	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
H3V22_RS05390	ENOG410681U	heavy metal transport detoxification protein
H3V22_RS05395	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H3V22_RS05405	ENOG4107XQC	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity)
H3V22_RS05410	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
H3V22_RS05415	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
H3V22_RS05425	ENOG4105JH5	thiaminase II
H3V22_RS05455	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
H3V22_RS05480	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
H3V22_RS05485	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
H3V22_RS05490	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
H3V22_RS05495	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H3V22_RS05500	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
H3V22_RS05505	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H3V22_RS05510	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
H3V22_RS05520	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
H3V22_RS05525	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
H3V22_RS05530	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
H3V22_RS05535	ENOG4108UIC	UPF0340 protein
H3V22_RS05540	ENOG4108YZG	isomerase
H3V22_RS05545	ENOG4107WAU	Protein tyrosine phosphatase
H3V22_RS05550	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H3V22_RS05555	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
H3V22_RS05560	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
H3V22_RS05565	ENOG4107104	thymidine kinase
H3V22_RS05570	ENOG41082DI	50s ribosomal protein l31
H3V22_RS05575	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
H3V22_RS05580	ENOG4105C26	Dehydrogenase
H3V22_RS05590	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
H3V22_RS05595	ENOG4105D2N	Aldolase
H3V22_RS05600	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H3V22_RS05610	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
H3V22_RS05615	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
H3V22_RS05645	ENOG4108RDQ	ABC transporter
H3V22_RS05680	ENOG4105RHY	Pfam:UPF0157
H3V22_RS05685	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
H3V22_RS05695	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
H3V22_RS05700	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
H3V22_RS05705	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
H3V22_RS05710	ENOG4107RHR	regulatoR
H3V22_RS05715	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
H3V22_RS05720	ENOG4108RMU	ferritin dps family protein
H3V22_RS05725	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
H3V22_RS05730	ENOG4105CNN	ABC, transporter
H3V22_RS05735	ENOG4105C2J	ABC transporter
H3V22_RS05740	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
H3V22_RS05745	ENOG4108RVA	ribokinase
H3V22_RS05750	ENOG4105ETE	Transcriptional regulator (LacI family
H3V22_RS05760	ENOG4105DFD	Na H antiporter
H3V22_RS05780	ENOG41068JE	domain protein
H3V22_RS05790	ENOG4105DG6	mannose-6-phosphate isomerase
H3V22_RS05795	ENOG4105CFC	Transporter
H3V22_RS05800	ENOG4105JXH	GntR family transcriptional regulator
H3V22_RS05805	ENOG4105VDH	Dihydroxyacetone kinase
H3V22_RS05810	ENOG4108UTZ	Dihydroxyacetone kinase
H3V22_RS05815	ENOG4105CMT	Dihydroxyacetone kinase
H3V22_RS05830	ENOG4105EG2	ABC transporter, permease
H3V22_RS05840	ENOG4107FKK	extracellular solute-binding protein family 1
H3V22_RS05855	ENOG4105ECB	domain protein
H3V22_RS05855	ENOG4105ECB	domain protein
H3V22_RS05860	ENOG4105CIS	alcohol dehydrogenase
H3V22_RS05880	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
H3V22_RS05885	ENOG4108UJD	30S ribosomal protein S9
H3V22_RS05890	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
H3V22_RS05895	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
H3V22_RS05905	ENOG4108JJB	ABC transporter
H3V22_RS05910	ENOG4108JJB	ABC transporter
H3V22_RS05915	ENOG4108ZT0	50S ribosomal protein l17
H3V22_RS05920	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H3V22_RS05925	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
H3V22_RS05935	ENOG41067V7	50S ribosomal protein L36
H3V22_RS05945	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
H3V22_RS05950	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
H3V22_RS05960	ENOG4105VPB	50S ribosomal protein L30
H3V22_RS05965	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
H3V22_RS05970	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
H3V22_RS05975	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
H3V22_RS05980	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
H3V22_RS05985	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
H3V22_RS05990	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H3V22_RS05995	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
H3V22_RS06000	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
H3V22_RS06010	ENOG41082SA	50s ribosomal protein l29
H3V22_RS06015	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
H3V22_RS06020	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
H3V22_RS06025	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
H3V22_RS06030	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
H3V22_RS06035	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H3V22_RS06040	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
H3V22_RS06045	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
H3V22_RS06050	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
H3V22_RS06055	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
H3V22_RS06065	ENOG4105C7N	Xanthine uracil vitamin C permease
H3V22_RS06085	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
H3V22_RS06095	ENOG4108Z66	YbaK ebsC protein
H3V22_RS06120	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
H3V22_RS06130	ENOG4105C2C	drug resistance transporter, Bcr CflA
H3V22_RS06140	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
H3V22_RS06145	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
H3V22_RS06155	ENOG4108ZAF	Molybdopterin
H3V22_RS06165	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
H3V22_RS06170	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
H3V22_RS06175	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
H3V22_RS06180	ENOG4105D06	uba thif-type nad fad binding protein
H3V22_RS06190	ENOG4105WH1	Two component transcriptional regulator luxr family
H3V22_RS06195	ENOG4105BZU	Histidine kinase
H3V22_RS06210	ENOG4105R3A	Nitrate reductase
H3V22_RS06215	ENOG4108IUE	nitrate reductase beta subunit
H3V22_RS06225	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
H3V22_RS06230	ENOG4105E0C	molybdate abc transporter
H3V22_RS06240	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
H3V22_RS06250	ENOG4107ZYJ	bioY protein
H3V22_RS06260	ENOG4107YCY	Transcriptional regulator
H3V22_RS06265	ENOG4107YCY	Transcriptional regulator
H3V22_RS06275	ENOG4107RJ1	sodium solute
H3V22_RS06280	ENOG4105J76	Periplasmic binding protein
H3V22_RS06285	ENOG4105WD1	Membrane
H3V22_RS06290	ENOG4108UZ3	Transporter
H3V22_RS06295	ENOG4105FDT	acyl-CoA dehydrogenase
H3V22_RS06300	ENOG4107R6U	sodium dicarboxylate symporter
H3V22_RS06305	ENOG4105CJ1	ABC, transporter
H3V22_RS06370	ENOG4105DFD	Na H antiporter
H3V22_RS06390	ENOG4105D01	(LipO)protein
H3V22_RS06395	ENOG4108UMI	ABC transporter, permease
H3V22_RS06400	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
H3V22_RS06420	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
H3V22_RS06430	ENOG4108HIZ	formate dehydrogenase alpha subunit
H3V22_RS06440	ENOG4105BZC	d-serine deaminase
H3V22_RS06460	ENOG4105CZM	Major Facilitator
H3V22_RS06465	ENOG41065XD	Transcriptional regulator
H3V22_RS06475	ENOG4105DFD	Na H antiporter
H3V22_RS06490	ENOG4105DYB	Isoaspartyl dipeptidase
H3V22_RS06500	ENOG4108TVJ	Nitroreductase
H3V22_RS06515	ENOG4105EVU	fructokinase
H3V22_RS06520	ENOG4105D7N	magnesium and cobalt transport protein CorA
H3V22_RS06525	ENOG4105CIY	formyltetrahydrofolate deformylase
H3V22_RS06530	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
H3V22_RS06535	ENOG4105VCP	PTS System
H3V22_RS06540	ENOG4105VZJ	PTS System
H3V22_RS06550	ENOG4105CK1	PTS System
H3V22_RS06555	ENOG4105SXS	Protein of unknown function (DUF456)
H3V22_RS06565	ENOG4108RPX	mosc domain containing protein
H3V22_RS06575	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
H3V22_RS06585	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H3V22_RS06590	ENOG4105CW7	secretion protein, HlyD family
H3V22_RS06615	ENOG4105CDY	transcriptional regulatory protein
H3V22_RS06620	ENOG4106I4J	membrane
H3V22_RS06625	ENOG4105VRS	hydrolase family 18
H3V22_RS06630	ENOG4105CJ3	phosphate transporter
H3V22_RS06635	ENOG4107GRR	phosphate transport regulator
H3V22_RS06645	ENOG4105C19	ABC transporter
H3V22_RS06650	ENOG4105EWM	Histidine kinase
H3V22_RS06655	ENOG4105CJZ	response regulator
H3V22_RS06680	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H3V22_RS06695	ENOG4105KTU	Transcriptional regulator, arsr family
H3V22_RS06700	ENOG4105PGM	cation diffusion facilitator family transporter
H3V22_RS06710	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
H3V22_RS06740	ENOG4105DKW	ABC transporter
H3V22_RS06745	ENOG4108W0I	acetyltransferase
H3V22_RS06750	ENOG4107T5V	SNARE associated Golgi
H3V22_RS06755	ENOG4105CK7	Sodium proline symporter
H3V22_RS06765	ENOG4105CHR	reductase
H3V22_RS06770	ENOG410681U	heavy metal transport detoxification protein
H3V22_RS06775	ENOG4105C59	p-type ATPase
H3V22_RS06780	ENOG4105VPX	protein, conserved in bacteria
H3V22_RS06785	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
H3V22_RS06790	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
H3V22_RS06795	ENOG4107U5W	ybbr family
H3V22_RS06860	ENOG4105D1F	ATP-binding protein
H3V22_RS06880	ENOG4105EFZ	amidohydrolase
H3V22_RS06895	ENOG4108UT2	hemolysin iii
H3V22_RS06910	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
H3V22_RS06920	ENOG41088SP	formiminoglutamate hydrolase
H3V22_RS06925	ENOG4105FR1	rard protein
H3V22_RS06930	ENOG4105DBV	ornithine carbamoyltransferase
H3V22_RS06935	ENOG4107DUR	UPF0457 protein
H3V22_RS06945	ENOG4106EQQ	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
H3V22_RS06950	ENOG4105DWD	nucleoside recognition domain protein
H3V22_RS06955	ENOG4105F27	Major Facilitator
H3V22_RS06960	ENOG4105VBF	alkaline shock protein
H3V22_RS06980	ENOG4105EHG	Permease protein
H3V22_RS06985	ENOG4105DQ5	transport system permease protein
H3V22_RS06990	ENOG4105E0A	ABC, transporter
H3V22_RS06995	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
H3V22_RS07000	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
H3V22_RS07010	ENOG4105BZ1	(ABC) transporter
H3V22_RS07030	ENOG4105KST	dependent repressor
H3V22_RS07035	ENOG4105DIK	(ABC) transporter
H3V22_RS07040	ENOG4105CC5	ABC transporter
H3V22_RS07045	ENOG4105DSE	periplasmic solute binding protein
H3V22_RS07055	ENOG410684G	monovalent cation H antiporter subunit F
H3V22_RS07060	ENOG4105IMY	monovalent cation H antiporter subunit E
H3V22_RS07075	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
H3V22_RS07080	ENOG4105C8S	subunit m
H3V22_RS07105	ENOG4108CIP	transcriptional regulator
H3V22_RS07110	ENOG4108KGH	TRANSCRIPTIONal
H3V22_RS07125	ENOG4106G6Q	Transcriptional regulator
H3V22_RS07130	ENOG4105C5Y	PTS System
H3V22_RS07135	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H3V22_RS07145	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
H3V22_RS07150	ENOG4105C94	Transporter
H3V22_RS07165	ENOG4105CFC	Transporter
H3V22_RS07175	ENOG4105D2N	Aldolase
H3V22_RS07190	ENOG4108XBJ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
H3V22_RS07195	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
H3V22_RS07200	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
H3V22_RS07210	ENOG4105DEN	Luciferase family
H3V22_RS07220	ENOG4105DJ2	Major Facilitator Superfamily
H3V22_RS07245	ENOG4105G9B	Transcriptional regulator
H3V22_RS07260	ENOG4105VEQ	Cold shock protein
H3V22_RS07270	ENOG4105VAW	lrga family
H3V22_RS07275	ENOG41067MG	lrgb family
H3V22_RS07280	ENOG4105NYY	transcriptional regulator, RpiR
H3V22_RS07285	ENOG4108VA3	3-hexulose-6-phosphate synthase
H3V22_RS07290	ENOG4105KVH	Transcriptional regulator
H3V22_RS07320	ENOG4105M6F	mutator MutT protein
H3V22_RS07350	ENOG4105CFC	Transporter
H3V22_RS07355	ENOG4108VEU	Thiamine monophosphate synthase
H3V22_RS07360	ENOG41080HI	glycine oxidase
H3V22_RS07370	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
H3V22_RS07375	ENOG4105D06	uba thif-type nad fad binding protein
H3V22_RS07380	ENOG4105K78	MarR family Transcriptional regulator
H3V22_RS07385	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
H3V22_RS07390	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
H3V22_RS07395	ENOG4105BZ1	(ABC) transporter
H3V22_RS07400	ENOG4105BZ1	(ABC) transporter
H3V22_RS07405	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
H3V22_RS07415	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
H3V22_RS07420	ENOG4105D5G	Transposase
H3V22_RS07425	ENOG4105CS2	ec 3.2.1.21
H3V22_RS07435	ENOG4108S3Y	transcriptional regulator
H3V22_RS07445	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
H3V22_RS07450	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
H3V22_RS07460	ENOG41067MG	lrgb family
H3V22_RS07465	ENOG4105Z9F	murein hydrolase regulator LrgA
H3V22_RS07470	ENOG4105DY9	regulatoR
H3V22_RS07475	ENOG4108HRK	Histidine kinase
H3V22_RS07495	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H3V22_RS07500	ENOG41081I9	integral membrane protein
H3V22_RS07505	ENOG4105F8D	glycoside hydrolase family 4
H3V22_RS07510	ENOG4105C2X	Arabinose 5-phosphate isomerase
H3V22_RS07515	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
H3V22_RS07550	ENOG4105DJ2	Major Facilitator Superfamily
H3V22_RS07575	ENOG4105ETU	transcriptional activator (TenA
H3V22_RS07615	ENOG4108K88	Membrane
H3V22_RS07625	ENOG4105DJB	Major Facilitator Superfamily
H3V22_RS07635	ENOG4108YBP	pseudouridine synthase
H3V22_RS07645	ENOG4107RA9	decarboxylase
H3V22_RS07670	ENOG4108V5C	ABC transporter
H3V22_RS07680	ENOG4105DQ5	transport system permease protein
H3V22_RS07685	ENOG4108HUF	Transporter
H3V22_RS07705	ENOG4105D4T	Citrate transporter
H3V22_RS07715	ENOG4105VRR	gCN5-related N-acetyltransferase
H3V22_RS07725	ENOG4105F8D	glycoside hydrolase family 4
H3V22_RS07735	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
H3V22_RS07750	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
H3V22_RS07755	ENOG4108HKT	sucrose-6-phosphate hydrolase
H3V22_RS07760	ENOG4105ETE	Transcriptional regulator (LacI family
H3V22_RS07765	ENOG41082BM	Transcriptional regulator, arsr family
H3V22_RS07785	ENOG4105CHH	sulfate transporter
H3V22_RS07805	ENOG4105TRT	Transcriptional regulator
H3V22_RS07810	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
H3V22_RS07815	ENOG4107RIQ	Sulfate adenylate transferase
H3V22_RS07820	ENOG410635A	Membrane
H3V22_RS07825	ENOG4108Z73	Siroheme synthase
H3V22_RS07830	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
H3V22_RS07835	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
H3V22_RS07840	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
H3V22_RS07845	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
H3V22_RS07850	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
H3V22_RS07855	ENOG4105C94	Transporter
H3V22_RS07860	ENOG4107FQX	Alpha-acetolactate decarboxylase
H3V22_RS07865	ENOG41067MG	lrgb family
H3V22_RS07870	ENOG4105VAW	lrga family
H3V22_RS07875	ENOG4105CMU	LysR family (Transcriptional regulator
H3V22_RS07880	ENOG4105C8J	)-transporter
H3V22_RS07895	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
H3V22_RS07950	ENOG4105CK5	oxidoreductase
H3V22_RS07960	ENOG4105CK5	oxidoreductase
H3V22_RS07970	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
H3V22_RS07980	ENOG4105EVH	UPF0753 protein
H3V22_RS07985	ENOG4108TWJ	NADH dehydrogenase subunit 5
H3V22_RS07990	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
H3V22_RS07995	ENOG4105CHU	acetyl-coa acetyltransferase
H3V22_RS08005	ENOG4105C1G	acyl-Coa dehydrogenase
H3V22_RS08010	ENOG4105CEY	Amp-dependent synthetase and ligase
H3V22_RS08015	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
H3V22_RS08020	ENOG4105DWT	malate dehydrogenase (quinone)
H3V22_RS08040	ENOG4105DEN	Luciferase family
H3V22_RS08050	ENOG4105DM4	PTS System
H3V22_RS08070	ENOG4105D82	Glutamate dehydrogenase
H3V22_RS08080	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
H3V22_RS08085	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
H3V22_RS08105	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
H3V22_RS08110	ENOG41090MY	MarR family Transcriptional regulator
H3V22_RS08125	ENOG4105C72	UPF0176 protein
H3V22_RS08135	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
H3V22_RS08145	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
H3V22_RS08155	ENOG4108YYS	metal-dependent hydrolase (By similarity)
H3V22_RS08160	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
H3V22_RS08180	ENOG4105C94	Transporter
H3V22_RS08185	ENOG4105D5U	fad dependent oxidoreductase
H3V22_RS08190	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
H3V22_RS08195	ENOG4105CQB	FAD linked oxidase domain protein
H3V22_RS08200	ENOG4105JXH	GntR family transcriptional regulator
H3V22_RS08235	ENOG4105DEN	Luciferase family
H3V22_RS08245	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
H3V22_RS08260	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
H3V22_RS08275	ENOG4105CS2	ec 3.2.1.21
H3V22_RS08280	ENOG4105CK1	PTS System
H3V22_RS08285	ENOG4105VCP	PTS System
H3V22_RS08295	ENOG4106VEM	tagatose-6-phosphate kinase
H3V22_RS08310	ENOG4105E98	transcriptional regulator DeoR family
H3V22_RS08315	ENOG4105EYF	MMPL domain protein
H3V22_RS08330	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
H3V22_RS08335	ENOG4108ZMQ	domain protein
H3V22_RS08340	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
H3V22_RS08360	ENOG4106F1P	AAA ATPase, central domain protein
H3V22_RS08380	ENOG4105F27	Major Facilitator
H3V22_RS08385	ENOG4105CMU	LysR family (Transcriptional regulator
H3V22_RS08405	ENOG4108IYU	L-aspartate oxidase
H3V22_RS08410	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
H3V22_RS08415	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
H3V22_RS08440	ENOG4105C54	Major Facilitator superfamily
H3V22_RS08445	ENOG4107QNK	)-transporter
H3V22_RS08475	ENOG41090UD	(LipO)protein
H3V22_RS08480	ENOG4105KT7	mgtC SapB transporter
H3V22_RS08485	ENOG4105KAV	tspo and mbr like protein
H3V22_RS08490	ENOG4105KVH	Transcriptional regulator
H3V22_RS08495	ENOG4107S9D	Alpha beta hydrolase
H3V22_RS08505	ENOG4105CIS	alcohol dehydrogenase
H3V22_RS08525	ENOG4105CT4	transporter
H3V22_RS08535	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H3V22_RS08555	ENOG4105CK5	oxidoreductase
H3V22_RS08575	ENOG4106PHM	regulatory protein
H3V22_RS08580	ENOG4105C6Z	Gluconate
H3V22_RS08585	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
H3V22_RS08605	ENOG41076QQ	Glycosyl transferase, family 2
H3V22_RS08620	ENOG4105C7K	acetolactate synthase
H3V22_RS08640	ENOG4108IA2	Sodium pantothenate symporter
H3V22_RS08670	ENOG4105K6V	RNA polymerase
H3V22_RS08695	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
H3V22_RS08710	ENOG4105C5X	domain protein
H3V22_RS08715	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
H3V22_RS08720	ENOG4105XTG	Pfam:DUF156
H3V22_RS08725	ENOG41087NI	Sulfite exporter TauE/SafE
H3V22_RS08730	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
H3V22_RS08765	ENOG4105C26	Dehydrogenase
H3V22_RS08780	ENOG4105ENY	Ethanolamine utilization protein eutH
H3V22_RS08800	ENOG4107QPD	alcohol dehydrogenase
H3V22_RS08845	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
H3V22_RS08920	ENOG4108UXE	Protein tyrosine phosphatase
H3V22_RS08930	ENOG4105C5X	domain protein
H3V22_RS08935	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
H3V22_RS08940	ENOG4105XTG	Pfam:DUF156
H3V22_RS08945	ENOG41087NI	Sulfite exporter TauE/SafE
H3V22_RS09000	ENOG410826E	Dna repair protein radc
H3V22_RS09005	ENOG4108KU9	integrase family
H3V22_RS09010	ENOG4105ZX1	Transposase C
H3V22_RS09035	ENOG41087NI	Sulfite exporter TauE/SafE
H3V22_RS09040	ENOG4105XTG	Pfam:DUF156
H3V22_RS09045	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
H3V22_RS09070	ENOG4105CCN	Peptidase M56
H3V22_RS09075	ENOG4107RVG	penicillin-binding protein
H3V22_RS09080	ENOG4108ZMQ	domain protein
H3V22_RS09085	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
H3V22_RS09095	ENOG4108BUD	transposase
H3V22_RS09110	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
H3V22_RS09115	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
H3V22_RS09120	ENOG4105D3Q	Sugar transferase
H3V22_RS09170	ENOG4105HTX	biosynthesis protein
H3V22_RS09235	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
H3V22_RS09240	ENOG4105Q2H	domain protein
H3V22_RS09255	ENOG4105BZU	Histidine kinase
H3V22_RS09275	ENOG4108JYZ	YitT family
H3V22_RS09280	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
H3V22_RS09285	ENOG4105CDU	Replicative dna helicase
H3V22_RS09290	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
H3V22_RS09295	ENOG4105BZR	domain protein
H3V22_RS09305	ENOG4105DWV	Homoserine O-trans-acetylase
H3V22_RS09315	ENOG4108UMN	azlc family
H3V22_RS09320	ENOG4108YYC	ycei family
H3V22_RS09325	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
H3V22_RS09330	ENOG4105CI2	imidazolone-5-propionate hydrolase
H3V22_RS09335	ENOG4105CGP	Urocanate hydratase
H3V22_RS09340	ENOG4105DWD	nucleoside recognition domain protein
H3V22_RS09345	ENOG4105C84	Histidine ammonia-lyase
H3V22_RS09350	ENOG4105U7G	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization (By similarity)
H3V22_RS09365	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H3V22_RS09370	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3V22_RS09375	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3V22_RS09380	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
H3V22_RS09385	ENOG410848D	S4 domain protein YaaA
H3V22_RS09395	ENOG4107ZQN	disulfide bond
H3V22_RS09400	ENOG4105RHA	ABC transporter, permease
H3V22_RS09405	ENOG4108IUX	(ABC) transporter
H3V22_RS09415	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
H3V22_RS09420	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
H3V22_RS09430	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
H3V22_RS09440	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
H3V22_RS09445	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
H3V22_RS09450	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
H3V22_RS09455	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
H3V22_RS09470	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
H3V22_RS09480	ENOG4105C28	cystathionine
H3V22_RS09485	ENOG4105C28	cystathionine
H3V22_RS09490	ENOG4105FA0	parb-like partition protein
H3V22_RS09495	ENOG4105D8X	mechanosensitive ion channel
H3V22_RS09500	ENOG4105VDK	protein, conserved in bacteria
H3V22_RS09505	ENOG4105C3G	gtp-binding protein
H3V22_RS09510	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
H3V22_RS09515	ENOG4108UUM	single-stranded DNA-binding protein
H3V22_RS09520	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
H3V22_RS09545	ENOG4105CS9	pantothenic acid kinase
H3V22_RS09565	ENOG4107QPK	)-transporter
H3V22_RS09570	ENOG4105C8J	)-transporter
H3V22_RS09575	ENOG4108TVJ	Nitroreductase
H3V22_RS09595	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
H3V22_RS09600	ENOG4105C2W	permease
H3V22_RS09605	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H3V22_RS09610	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H3V22_RS09620	ENOG4108V4B	ThiJ pfpI
H3V22_RS09640	ENOG4105C94	Transporter
H3V22_RS09655	ENOG4105FBA	Phospholipase Carboxylesterase
H3V22_RS09670	ENOG4105K7K	Transcriptional regulator
H3V22_RS09690	ENOG410839T	multidrug resistance protein
H3V22_RS09695	ENOG41080TC	multidrug resistance protein
H3V22_RS09700	ENOG4108R6G	acetyltransferase
H3V22_RS09710	ENOG4105C8Y	Acetylornithine aminotransferase
H3V22_RS09715	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
H3V22_RS09720	ENOG4105D94	Major Facilitator Superfamily
H3V22_RS09740	ENOG4108VX5	3-methyladenine DNA glycosylase
H3V22_RS09745	ENOG4105EMY	transcriptional regulator
H3V22_RS09750	ENOG4105CBC	glutamate synthase
H3V22_RS09755	ENOG4105BZ8	glutamate synthase
H3V22_RS09765	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
H3V22_RS09770	ENOG4105DTQ	mandelate racemase muconate lactonizing
H3V22_RS09775	ENOG4107SN7	NLP P60 protein
H3V22_RS09785	ENOG4105C5Y	PTS System
H3V22_RS09790	ENOG4105CG3	alpha amylase, catalytic region
H3V22_RS09795	ENOG4107414	GntR family transcriptional regulator
H3V22_RS09810	ENOG4105C6E	dna polymerase iii
H3V22_RS09815	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
H3V22_RS09825	ENOG4108NRW	Phospholipase, patatin family
H3V22_RS09850	ENOG4105CXN	decarboxylase
H3V22_RS09855	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
H3V22_RS09860	ENOG4105X0R	protein from nitrogen regulatory protein P-II
H3V22_RS09865	ENOG4105FA2	dna polymerase iii
H3V22_RS09870	ENOG4105MA4	psp1 domain protein
H3V22_RS09880	ENOG41060K3	Methyltransferase
H3V22_RS09885	ENOG4105VC4	domain protein
H3V22_RS09890	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
H3V22_RS09895	ENOG4105KRN	Transcriptional regulator, abrb family
H3V22_RS09900	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
H3V22_RS09905	ENOG4105F8V	Hydrolase, tatD family
H3V22_RS09910	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
H3V22_RS09920	ENOG4105W42	Veg protein
H3V22_RS09925	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
H3V22_RS09930	ENOG4105DFT	pur operon repressor
H3V22_RS09935	ENOG4105KME	endoribonuclease L-psp
H3V22_RS09940	ENOG4105K4W	Could be involved in septation (By similarity)
H3V22_RS09945	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
H3V22_RS09950	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
H3V22_RS09955	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
H3V22_RS09960	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
H3V22_RS09965	ENOG4108JA2	transcriptioN-repair coupling factor
H3V22_RS09975	ENOG4108IY2	MazG family
H3V22_RS09980	ENOG41082I2	s4 domain protein
H3V22_RS09990	ENOG41060GV	RNA binding s1 domain protein
H3V22_RS10000	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
H3V22_RS10005	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H3V22_RS10010	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
H3V22_RS10015	ENOG4105C6T	cysteine synthase
H3V22_RS10025	ENOG4105KRF	dihydroneopterin aldolase
H3V22_RS10030	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H3V22_RS10125	ENOG4105ME7	Membrane
H3V22_RS10130	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H3V22_RS10135	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
H3V22_RS10140	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
H3V22_RS10145	ENOG4105D9N	nucleoside
H3V22_RS10150	ENOG4105KEX	transcriptional regulator, ctsr
H3V22_RS10155	ENOG4108Z0C	Uvrb UvrC protein
H3V22_RS10160	ENOG41066A3	ATP guanido phosphotransferase
H3V22_RS10165	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H3V22_RS10170	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
H3V22_RS10175	ENOG4105CTP	PilT protein domain protein
H3V22_RS10180	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
H3V22_RS10195	ENOG4105D7W	serine acetyltransferase
H3V22_RS10200	ENOG4105C8N	cysteinyl-tRNA synthetase
H3V22_RS10205	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H3V22_RS10210	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H3V22_RS10235	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
H3V22_RS10240	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
H3V22_RS10245	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
H3V22_RS10250	ENOG4108VZM	50s ribosomal protein L10
H3V22_RS10255	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
H3V22_RS10260	ENOG4107Y49	methyltransferase
H3V22_RS10265	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H3V22_RS10270	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H3V22_RS10280	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
H3V22_RS10285	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
H3V22_RS10290	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
H3V22_RS10295	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
H3V22_RS10320	ENOG4105EXW	epimerase dehydratase
H3V22_RS10325	ENOG4105CM2	brancheD-chain amino acid aminotransferase
H3V22_RS10335	ENOG4105ZMH	deoxynucleoside kinase
H3V22_RS10345	ENOG4108Z6B	deaminase
H3V22_RS10350	ENOG410667J	hydrolase
H3V22_RS10355	ENOG4107YFT	Nadph-dependent fmn reductase
H3V22_RS10360	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
H3V22_RS10365	ENOG4107YEI	lmbE family
H3V22_RS10375	ENOG4105QEK	Transcriptional regulator
H3V22_RS10380	ENOG4105CI1	PTS System
H3V22_RS10385	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
H3V22_RS10390	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
H3V22_RS10400	ENOG4105DWF	phosphomethylpyrimidine kinase
H3V22_RS10405	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
H3V22_RS10415	ENOG4105M08	Membrane
H3V22_RS10420	ENOG4107QHQ	amino acid
H3V22_RS10425	ENOG4107R7I	amino acid
H3V22_RS10430	ENOG4105D6U	Sodium Glutamate Symporter
H3V22_RS10445	ENOG4108UMI	ABC transporter, permease
H3V22_RS10450	ENOG4105D01	(LipO)protein
H3V22_RS10455	ENOG4108IJ2	phosphate acetyltransferase
H3V22_RS10460	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
H3V22_RS10465	ENOG4105QAT	UPF0741 protein
H3V22_RS10480	ENOG4105DCI	Phosphohydrolase
H3V22_RS10485	ENOG4108XFG	YwhD family
H3V22_RS10500	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
H3V22_RS10505	ENOG4108U1V	ABC transporter, permease
H3V22_RS10515	ENOG4108VQT	Alpha beta hydrolase fold protein
H3V22_RS10530	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
H3V22_RS10540	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
H3V22_RS10545	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
H3V22_RS10550	ENOG4105ETD	TRANSCRIPTIONal
H3V22_RS10595	ENOG4105EBR	Carboxylesterase
H3V22_RS10600	ENOG4105NRR	Uncharacterized protein conserved in bacteria (DUF2188)
H3V22_RS10620	ENOG4108M15	ABC transporter
H3V22_RS10625	ENOG4105CJW	magnesium transporter
H3V22_RS10645	ENOG4105HMI	Membrane
H3V22_RS10660	ENOG4105CMD	Transcriptional regulator, GntR family
H3V22_RS10665	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
H3V22_RS10670	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
H3V22_RS10675	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
H3V22_RS10680	ENOG4107QNK	)-transporter
H3V22_RS10690	ENOG4105C26	Dehydrogenase
H3V22_RS10695	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
H3V22_RS10700	ENOG4105CI2	imidazolone-5-propionate hydrolase
H3V22_RS10710	ENOG4105C85	amino acid
H3V22_RS10715	ENOG4105CH6	catalase
H3V22_RS10725	ENOG4105CK1	PTS System
H3V22_RS10730	ENOG4105VCP	PTS System
H3V22_RS10735	ENOG4105CS2	ec 3.2.1.21
H3V22_RS10740	ENOG4105EMD	TRANSCRIPTIONal
H3V22_RS10750	ENOG4105CIG	ABC transporter
H3V22_RS10765	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
H3V22_RS10780	ENOG4105C5I	Dehydrogenase
H3V22_RS10790	ENOG4105CI1	PTS System
H3V22_RS10795	ENOG4105F8D	glycoside hydrolase family 4
H3V22_RS10800	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
H3V22_RS10820	ENOG4105CI1	PTS System
H3V22_RS10825	ENOG4105ETE	Transcriptional regulator (LacI family
H3V22_RS10850	ENOG4105DXX	methyltransferase
H3V22_RS10860	ENOG4108J59	Extracellular solute-binding protein, family 5
H3V22_RS10870	ENOG4105E70	isomerase
H3V22_RS10875	ENOG4105DE4	1-phosphofructokinase
H3V22_RS10880	ENOG4105D2M	Aldolase
H3V22_RS10890	ENOG4105DAS	pts system
H3V22_RS10895	ENOG4105ETZ	PTS System
H3V22_RS10900	ENOG4105F3R	pts system mannose fructose sorbose family iid
H3V22_RS10915	ENOG4105C19	ABC transporter
H3V22_RS10935	ENOG4105CN9	Peptidase m42 family protein
H3V22_RS10940	ENOG4105ECK	Fatty Acid Desaturase
H3V22_RS10945	ENOG4105CID	antiterminator
H3V22_RS10950	ENOG4105C5Y	PTS System
H3V22_RS10955	ENOG4105CS2	ec 3.2.1.21
H3V22_RS10960	ENOG4105CS2	ec 3.2.1.21
H3V22_RS10980	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
H3V22_RS10985	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H3V22_RS10990	ENOG4105E66	phosphoriboisomerase A
H3V22_RS11030	ENOG4108RYK	Nad-dependent epimerase dehydratase
H3V22_RS11055	ENOG4105C54	Major Facilitator superfamily
H3V22_RS11060	ENOG4105CSH	Transporter
H3V22_RS11065	ENOG4105DC7	peptidase M24
H3V22_RS11090	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H3V22_RS11095	ENOG4105CTU	Proline racemase
H3V22_RS11105	ENOG4105DFD	Na H antiporter
H3V22_RS11110	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H3V22_RS11115	ENOG4105C26	Dehydrogenase
H3V22_RS11120	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3V22_RS11135	ENOG4107S6Z	Na H antiporter
H3V22_RS11150	ENOG4107R5R	arsenical pump membrane protein
H3V22_RS11160	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
H3V22_RS11210	ENOG41085FC	arsR family transcriptional regulator
H3V22_RS11255	ENOG4108IJ7	Glycine betaine
H3V22_RS11260	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H3V22_RS11270	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
H3V22_RS11285	ENOG4105D3Q	Sugar transferase
H3V22_RS11290	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
H3V22_RS11295	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
H3V22_RS11300	ENOG4105CMR	udp-glucose 4-epimerase
H3V22_RS11335	ENOG4107VDP	teichoic acid biosynthesis
H3V22_RS11340	ENOG4107SJB	teichoic acid biosynthesis
H3V22_RS11350	ENOG4108IAJ	Nad-dependent epimerase dehydratase
H3V22_RS11365	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
H3V22_RS11375	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
H3V22_RS11385	ENOG4108SA1	esterase
H3V22_RS11390	ENOG4105FDP	GntR family transcriptional regulator
H3V22_RS11395	ENOG4105DVE	abc transporter atp-binding protein
H3V22_RS11405	ENOG41090E6	transcriptional regulator MERR family
H3V22_RS11410	ENOG4105DP8	Major facilitator superfamily MFS_1
H3V22_RS11415	ENOG41090MY	MarR family Transcriptional regulator
H3V22_RS11425	ENOG4107XC4	flavin reductase domain protein, FMN-binding
H3V22_RS11430	ENOG4105FBA	Phospholipase Carboxylesterase
H3V22_RS11440	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H3V22_RS11445	ENOG4107QN2	dihydrolipoyl dehydrogenase
H3V22_RS11450	ENOG4105CHR	reductase
H3V22_RS11455	ENOG4105EMD	TRANSCRIPTIONal
H3V22_RS11465	ENOG410787A	Pts system, glucitol sorbitol-specific
H3V22_RS11470	ENOG4105DZY	Pts system, glucitol sorbitol-specific
H3V22_RS11480	ENOG4105CSH	Transporter
H3V22_RS11485	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
H3V22_RS11520	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
H3V22_RS11530	ENOG4105CHR	reductase
H3V22_RS11545	ENOG4105UNS	Pfam:DUF419
H3V22_RS11565	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H3V22_RS11575	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
H3V22_RS11585	ENOG4105E98	transcriptional regulator DeoR family
H3V22_RS11590	ENOG4105DET	Rhamnulokinase
H3V22_RS11595	ENOG4105DKG	l-rhamnose isomerase
H3V22_RS11600	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
H3V22_RS11615	ENOG4105C26	Dehydrogenase
H3V22_RS11630	ENOG4108DBC	nitroreductase
H3V22_RS11665	ENOG4105CV8	reductase
H3V22_RS11685	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H3V22_RS11690	ENOG4107XVH	Transcriptional regulator
H3V22_RS11705	ENOG4105DU0	nucleoside hydrolase
H3V22_RS11710	ENOG4108MEK	Metal-binding protein YodA
H3V22_RS11720	ENOG4105DMQ	Methyltransferase
H3V22_RS11730	ENOG4105CS2	ec 3.2.1.21
H3V22_RS11740	ENOG4105EMD	TRANSCRIPTIONal
H3V22_RS11745	ENOG4105VCP	PTS System
H3V22_RS11755	ENOG4105CK1	PTS System
H3V22_RS11760	ENOG4105D5G	Transposase
H3V22_RS11770	ENOG4105BZ1	(ABC) transporter
H3V22_RS11775	ENOG4105KPV	Transcriptional regulator
H3V22_RS11780	ENOG4108JU3	Alkyl hydroperoxide reductase
H3V22_RS11795	ENOG410650H	(LipO)protein
H3V22_RS11800	ENOG4105DBE	peroxidase
H3V22_RS11805	ENOG4107SJW	iron permease, FTR1
H3V22_RS11810	ENOG4108M15	ABC transporter
H3V22_RS11815	ENOG4105KCT	ABC transporter
H3V22_RS11820	ENOG4105BZU	Histidine kinase
H3V22_RS11825	ENOG4108S01	response regulator
H3V22_RS11835	ENOG4105IIP	Membrane
H3V22_RS11840	ENOG4105CXY	transporter
H3V22_RS11845	ENOG41075H3	AraC family transcriptional regulator
H3V22_RS11855	ENOG4105CAY	ferredoxin--nadp reductase
H3V22_RS11860	ENOG4105CPC	Aldo Keto reductase
H3V22_RS11885	ENOG4108R3E	Dna-3-methyladenine glycosylase i
H3V22_RS11890	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
H3V22_RS11910	ENOG4105K56	Transcriptional regulator
H3V22_RS11925	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
H3V22_RS11930	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
H3V22_RS11935	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
H3V22_RS11940	ENOG4105CYW	agmatinase
H3V22_RS11965	ENOG4105D03	DNA-3-methyladenine glycosylase II
H3V22_RS11975	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
H3V22_RS11980	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H3V22_RS11995	ENOG4105D9U	N-acetyltransferase
H3V22_RS12025	ENOG4107SUZ	Sodium/hydrogen exchanger family
H3V22_RS12045	ENOG4105C26	Dehydrogenase
H3V22_RS12060	ENOG4105EWC	Purine nucleoside phosphorylase
H3V22_RS12065	ENOG4108URH	decarboxylase
H3V22_RS12075	ENOG4107XJU	UPF0178 protein
H3V22_RS12090	ENOG4108JJ9	ABC, transporter
H3V22_RS12095	ENOG4108JJ8	(ABC) transporter
H3V22_RS12100	ENOG4105K56	Transcriptional regulator
H3V22_RS12105	ENOG4105CKI	cobalamin synthesis protein
H3V22_RS12110	ENOG4107QM2	Aldo Keto reductase
H3V22_RS12120	ENOG4105E98	transcriptional regulator DeoR family
H3V22_RS12125	ENOG4105DE4	1-phosphofructokinase
H3V22_RS12130	ENOG4105DM4	PTS System
H3V22_RS12135	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
H3V22_RS12140	ENOG4105C37	(CBS) domain
H3V22_RS12145	ENOG4105VCH	membrane
H3V22_RS12150	ENOG4105FE9	pseudouridine synthase
H3V22_RS12160	ENOG4108VTV	Inherit from NOG: Membrane
H3V22_RS12175	ENOG4105K7K	Transcriptional regulator
H3V22_RS12185	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
H3V22_RS12190	ENOG4107ZAE	6-carboxy-5,6,7,8-tetrahydropterin synthase
H3V22_RS12200	ENOG4105DDQ	anthranilate synthase
H3V22_RS12205	ENOG4105CRQ	synthase (Component I)
H3V22_RS12220	ENOG4105E0M	Sulfatase
H3V22_RS12230	ENOG4105C5H	ABC transporter
H3V22_RS12235	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H3V22_RS12240	ENOG4108IJ8	ABC transporter
H3V22_RS12245	ENOG4105E90	ABC transporter
H3V22_RS12250	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H3V22_RS12255	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
H3V22_RS12260	ENOG4105DUX	Transporter
H3V22_RS12265	ENOG4105DUX	Transporter
H3V22_RS12270	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
H3V22_RS12285	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H3V22_RS12290	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H3V22_RS12300	ENOG4105DHS	permease protein
H3V22_RS12305	ENOG4105CM4	permease protein
H3V22_RS12310	ENOG4108IPW	abc transporter atp-binding protein
H3V22_RS12320	ENOG4105D4A	Cell wall formation (By similarity)
H3V22_RS12350	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
H3V22_RS12360	ENOG4105DWK	Membrane
H3V22_RS12365	ENOG4105BZU	Histidine kinase
H3V22_RS12370	ENOG4105ESV	Glycosyl transferase, family 4
H3V22_RS12375	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
H3V22_RS12385	ENOG4105EPR	degv family
H3V22_RS12400	ENOG4105MS2	ribosomal subunit Interface protein
H3V22_RS12405	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
H3V22_RS12425	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3V22_RS12440	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
H3V22_RS12445	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H3V22_RS12460	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
H3V22_RS12465	ENOG4108S4C	acetyltransferase
H3V22_RS12475	ENOG4105C3M	thioredoxin reductase
H3V22_RS12480	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
H3V22_RS12485	ENOG4105CHW	UPF0052 protein
H3V22_RS12495	ENOG4105CIE	May be required for sporulation (By similarity)
H3V22_RS12500	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H3V22_RS12515	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
H3V22_RS12520	ENOG4105BZA	Phosphoglycerate kinase
H3V22_RS12525	ENOG4105CP7	Triose-phosphate isomerase
H3V22_RS12535	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
H3V22_RS12540	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
H3V22_RS12545	ENOG4105XZU	Preprotein translocase, subunit SecG
H3V22_RS12555	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
H3V22_RS12560	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
H3V22_RS12580	ENOG4105WQG	acetyltransferase
H3V22_RS12585	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
H3V22_RS12625	ENOG4105N14	lysine exporter protein LysE YggA
H3V22_RS12635	ENOG4107Y9E	nuclease
H3V22_RS12650	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
H3V22_RS12655	ENOG4108HK0	-acetyltransferase
H3V22_RS12670	ENOG4105CKI	cobalamin synthesis protein
H3V22_RS12685	ENOG4107T5J	pyridine nucleotide-disulfide oxidoreductase
H3V22_RS12690	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
H3V22_RS12695	ENOG4105CKI	cobalamin synthesis protein
H3V22_RS12725	ENOG4105CZN	Potassium uptake protein
H3V22_RS12740	ENOG4105CSH	Transporter
H3V22_RS12745	ENOG4108ZHJ	Organic hydroperoxide resistance protein
H3V22_RS12770	ENOG4105FF2	Type I DHQase
H3V22_RS12780	ENOG4105SZ6	Thioredoxin
H3V22_RS12785	ENOG41080E8	Transcriptional regulator, Spx MgsR family
H3V22_RS12790	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
H3V22_RS12805	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
H3V22_RS12810	ENOG4108UMI	ABC transporter, permease
H3V22_RS12815	ENOG4105D01	(LipO)protein
H3V22_RS12825	ENOG4105C3K	feS assembly ATPase SufC
H3V22_RS12830	ENOG4105JRK	feS assembly protein SufD
H3V22_RS12835	ENOG4105C9B	Cysteine desulfurase
H3V22_RS12840	ENOG4108UNV	SUF system FeS assembly protein, NifU family
H3V22_RS12845	ENOG4105DIW	FeS assembly protein SUFB
H3V22_RS12850	ENOG4107QNK	)-transporter
H3V22_RS12855	ENOG4105E2R	ROK family
H3V22_RS12860	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
H3V22_RS12865	ENOG4105D7K	pfkb domain protein
H3V22_RS12870	ENOG4108UHU	Aldolase
H3V22_RS12875	ENOG4105CXK	mandelate racemase muconate lactonizing
H3V22_RS12885	ENOG41067QW	Transcriptional regulator
H3V22_RS12895	ENOG4105ZMJ	n-acetylmuramoyl-l-alanine amidase
H3V22_RS12905	ENOG4105I3N	Conserved Protein
H3V22_RS12915	ENOG4107R8B	5'-nucleotidase
H3V22_RS12920	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
H3V22_RS12925	ENOG4105MMD	transcriptional regulator
H3V22_RS12935	ENOG4105DQ6	Transposase
H3V22_RS12950	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
H3V22_RS12955	ENOG4105C5I	Dehydrogenase
H3V22_RS12965	ENOG4108FN8	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
H3V22_RS12970	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
H3V22_RS12975	ENOG4106C1H	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
H3V22_RS12980	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
H3V22_RS12985	ENOG41083MR	nifu domain-containing protein
H3V22_RS13000	ENOG4105ZKE	UPF0349 protein
H3V22_RS13005	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
H3V22_RS13020	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
H3V22_RS13030	ENOG4105KA0	thioesterase Superfamily protein
H3V22_RS13035	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
H3V22_RS13040	ENOG4105D5G	Transposase
H3V22_RS13050	ENOG4105W4C	monovalent cation H antiporter subunit F
H3V22_RS13055	ENOG4105SC1	monovalent cation H antiporter subunit E
H3V22_RS13060	ENOG4108JPZ	Monovalent cation H antiporter subunit D
H3V22_RS13075	ENOG4105D65	subunit l
H3V22_RS13085	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
H3V22_RS13095	ENOG41060GV	RNA binding s1 domain protein
H3V22_RS13100	ENOG4105C26	Dehydrogenase
H3V22_RS13105	ENOG4105C8Y	Acetylornithine aminotransferase
H3V22_RS13110	ENOG4105D82	Glutamate dehydrogenase
H3V22_RS13115	ENOG4105CH7	arginosuccinase
H3V22_RS13120	ENOG4105CDH	Citrulline--aspartate ligase
H3V22_RS13150	ENOG4105C3F	Signal peptidase i
H3V22_RS13160	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H3V22_RS13165	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
H3V22_RS13185	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
H3V22_RS13190	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
H3V22_RS13195	ENOG4105EPR	degv family
H3V22_RS13200	ENOG4108KP7	hydrolase
H3V22_RS13205	ENOG4105VG1	fes assembly suf system protein
H3V22_RS13210	ENOG4107V6Q	Cyclic nucleotide-binding domain
H3V22_RS13215	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H3V22_RS13225	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
H3V22_RS13240	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H3V22_RS13245	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H3V22_RS13255	ENOG4108JQ7	(ABC) transporter
H3V22_RS13260	ENOG4108J59	Extracellular solute-binding protein, family 5
H3V22_RS13265	ENOG4108J59	Extracellular solute-binding protein, family 5
H3V22_RS13270	ENOG4108J59	Extracellular solute-binding protein, family 5
H3V22_RS13275	ENOG4108J59	Extracellular solute-binding protein, family 5
H3V22_RS13280	ENOG4105C31	Tryptophanyl-tRNA synthetase
H3V22_RS13285	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
H3V22_RS13290	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
H3V22_RS13300	ENOG4105DPN	Oligoendopeptidase f
H3V22_RS13305	ENOG4105T58	Dithiol-disulfide isomerase
H3V22_RS13310	ENOG4108Z18	K06886 hemoglobin
H3V22_RS13315	ENOG4105MIX	Adenylate cyclase
H3V22_RS13320	ENOG4106EFP	UPF0738 protein
H3V22_RS13335	ENOG4105EMS	pseudouridine synthase
H3V22_RS13340	ENOG4105CJW	magnesium transporter
H3V22_RS13360	ENOG4105BZG	amino acid carrier protein
H3V22_RS13375	ENOG4108PK2	permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl- diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis, thereby generating glycolipid-anchored LTA. Appears to play an important role in virulence
H3V22_RS13410	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
H3V22_RS13415	ENOG4107TS3	membrane protein, TerC
H3V22_RS13430	ENOG4105BZU	Histidine kinase
H3V22_RS13435	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
H3V22_RS13500	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
H3V22_RS13505	ENOG4105E4F	Isochorismate synthase
H3V22_RS13510	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
H3V22_RS13515	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
H3V22_RS13520	ENOG4108IPT	Naphthoate synthase
H3V22_RS13530	ENOG4105CHM	Aminotransferase
H3V22_RS13540	ENOG4108TGC	Acyltransferase
H3V22_RS13545	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
H3V22_RS13545	ENOG4108FQ0	the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis
H3V22_RS13550	ENOG4108HPG	-acetyltransferase
H3V22_RS13560	ENOG4108KGH	TRANSCRIPTIONal
H3V22_RS13565	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
H3V22_RS13570	ENOG4107F3J	Amp-dependent synthetase and ligase
H3V22_RS13575	ENOG4105CHU	acetyl-coa acetyltransferase
H3V22_RS13590	ENOG4105EY8	ABC transporter
H3V22_RS13605	ENOG4105K64	Glycosyl transferase, family 2
H3V22_RS13610	ENOG4105FQP	Beta-lactamase
H3V22_RS13615	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
H3V22_RS13620	ENOG4107SJB	teichoic acid biosynthesis
H3V22_RS13630	ENOG4108I69	Glycosyl transferases group 1
H3V22_RS13655	ENOG4105K64	Glycosyl transferase, family 2
H3V22_RS13670	ENOG4105EY8	ABC transporter
H3V22_RS13685	ENOG41060D1	Quinol oxidase
H3V22_RS13690	ENOG4105CCU	oxidase (Subunit III)
H3V22_RS13695	ENOG4105BZ9	Cytochrome C oxidase, subunit I
H3V22_RS13700	ENOG4105E2S	oxidase) subunit II
H3V22_RS13715	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
H3V22_RS13725	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
H3V22_RS13730	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
H3V22_RS13740	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
H3V22_RS13745	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
H3V22_RS13755	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
H3V22_RS13760	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
H3V22_RS13765	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
H3V22_RS13770	ENOG4105DC1	bifunctional purine biosynthesis protein purh
H3V22_RS13775	ENOG4105C12	Phosphoribosylglycinamide synthetase
H3V22_RS13785	ENOG4108JJB	ABC transporter
H3V22_RS13800	ENOG4105DR4	Methyltransferase
H3V22_RS13810	ENOG4107Y7Q	pfkb domain protein
H3V22_RS13815	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
H3V22_RS13825	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H3V22_RS13830	ENOG4105DIN	metallophosphoesterase
H3V22_RS13850	ENOG4107ZYR	domain protein
H3V22_RS13855	ENOG4105D5G	Transposase
H3V22_RS13865	ENOG4106148	UPF0356 protein
H3V22_RS13870	ENOG4108X4Q	Hydrolase
H3V22_RS13880	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H3V22_RS13890	ENOG4107RUY	(E1 component), alpha subunit
H3V22_RS13895	ENOG4105CPP	Dehydrogenase, E1 component
H3V22_RS13900	ENOG4105C7S	Dehydrogenase
H3V22_RS13905	ENOG4107QN2	dihydrolipoyl dehydrogenase
H3V22_RS13910	ENOG4105WBI	UPF0223 protein
H3V22_RS13920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3V22_RS13925	ENOG4105F38	ABC transporter, permease
H3V22_RS13930	ENOG4105D38	putrescine abc transporter
H3V22_RS13935	ENOG4107RUE	extracellular solute-binding protein family 1
H3V22_RS13955	ENOG4105ECY	inositol monophosphatase
H3V22_RS13965	ENOG4105CI3	gtp-binding protein typa
H3V22_RS13970	ENOG4105QA2	
H3V22_RS14050	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H3V22_RS14070	ENOG4108UUM	single-stranded DNA-binding protein
H3V22_RS14095	ENOG4108KU9	integrase family
H3V22_RS14100	ENOG4105ZX1	Transposase C
H3V22_RS14105	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
H3V22_RS14110	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H3V22_RS14125	ENOG4105D5G	Transposase
H3V22_RS14140	ENOG4105D5G	Transposase
H3V22_RS14145	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
H3V22_RS14150	ENOG4105FFM	Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity)
H3V22_RS14155	ENOG4105D5G	Transposase
H3V22_RS14240	ENOG4105DZR	Type I site-specific deoxyribonuclease
H3V22_RS14255	ENOG4105WKT	Replication Protein
H3V22_RS14285	ENOG41085FC	arsR family transcriptional regulator
H3V22_RS14350	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase