locus-tag	class	description
CPG32_RS00010	COG0745	RESPONSE REGULATOR receiver
CPG32_RS00020	COG2814	Major facilitator Superfamily
CPG32_RS00025	COG2272	Belongs to the type-B carboxylesterase lipase family
CPG32_RS00030	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CPG32_RS00035	COG1063	alcohol dehydrogenase
CPG32_RS00055	COG1174	glycine betaine transport
CPG32_RS00085	COG1346	cytolysis
CPG32_RS00090	COG1380	Effector of murein hydrolase LrgA
CPG32_RS00100	COG3279	Response regulator of the LytR AlgR family
CPG32_RS00105	COG3275	phosphorelay sensor kinase activity
CPG32_RS00115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CPG32_RS00120	COG0456	acetyltransferase
CPG32_RS00130	COG0706	membrane insertase activity
CPG32_RS00140	COG0531	amino acid
CPG32_RS00160	COG1113	amino acid transport
CPG32_RS00180	COG2814	Major facilitator Superfamily
CPG32_RS00190	COG1929	Belongs to the glycerate kinase type-1 family
CPG32_RS00200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CPG32_RS00205	COG0741	lytic transglycosylase activity
CPG32_RS00210	COG0588	phosphoglycerate mutase activity
CPG32_RS00220	COG2814	Major facilitator Superfamily
CPG32_RS00225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPG32_RS00230	COG0765	amino acid transport
CPG32_RS00235	COG1126	abc transporter atp-binding protein
CPG32_RS00275	COG1131	(ABC) transporter
CPG32_RS00285	COG2116	formate transmembrane transporter activity
CPG32_RS00295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CPG32_RS00300	COG2146	nitrite reductase [NAD(P)H] activity
CPG32_RS00310	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CPG32_RS00315	COG1140	nitrate reductase beta subunit
CPG32_RS00325	COG2181	nitrate reductase activity
CPG32_RS00335	COG4585	Histidine kinase
CPG32_RS00345	COG2223	nitrite transmembrane transporter activity
CPG32_RS00350	COG1846	Transcriptional regulator
CPG32_RS00390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPG32_RS00390	COG1263	PTS System
CPG32_RS00415	COG0534	Mate efflux family protein
CPG32_RS00425	COG1124	(ABC) transporter
CPG32_RS00430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPG32_RS00440	COG0601	transmembrane transport
CPG32_RS00450	COG0829	nickel cation binding
CPG32_RS00465	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CPG32_RS00470	COG0804	urea catabolic process
CPG32_RS00480	COG0831	urea catabolic process
CPG32_RS00485	COG4413	Urea transporter
CPG32_RS00495	COG4716	Myosin-crossreactive antigen
CPG32_RS00500	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CPG32_RS00505	COG2962	Rard protein
CPG32_RS00550	COG2814	Major facilitator Superfamily
CPG32_RS00555	COG0583	DNA-binding transcription factor activity
CPG32_RS00595	COG2314	TM2 domain
CPG32_RS00600	COG0492	ferredoxin-NADP+ reductase activity
CPG32_RS00615	COG0604	alcohol dehydrogenase
CPG32_RS00620	COG2822	iron ion transport
CPG32_RS00625	COG2837	iron assimilation
CPG32_RS00630	COG0672	)-iron permease
CPG32_RS00635	COG0805	protein transport
CPG32_RS00640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CPG32_RS00645	COG0456	acetyltransferase
CPG32_RS00655	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CPG32_RS00660	COG1620	l-lactate permease
CPG32_RS00665	COG0297	glycogen (starch) synthase activity
CPG32_RS00670	COG0579	oxidoreductase
CPG32_RS00720	COG2814	Major facilitator Superfamily
CPG32_RS00730	COG1566	PFAM secretion protein HlyD family protein
CPG32_RS00735	COG2814	Major facilitator Superfamily
CPG32_RS00760	COG0598	Magnesium transport protein CorA
CPG32_RS00765	COG1304	FMN binding
CPG32_RS00770	COG2094	Belongs to the DNA glycosylase MPG family
CPG32_RS00780	COG2017	converts alpha-aldose to the beta-anomer
CPG32_RS00785	COG2258	MOSC domain
CPG32_RS00790	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CPG32_RS00795	COG1266	CAAX protease self-immunity
CPG32_RS00810	COG1028	Short-chain dehydrogenase reductase Sdr
CPG32_RS00830	COG1737	Transcriptional regulator
CPG32_RS00835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPG32_RS00835	COG1263	PTS System
CPG32_RS00845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CPG32_RS00865	COG1113	amino acid transport
CPG32_RS00870	COG1737	Transcriptional regulator
CPG32_RS00875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPG32_RS00875	COG1263	PTS System
CPG32_RS00880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CPG32_RS00890	COG1349	DNA-binding transcription factor activity
CPG32_RS00900	COG1316	TRANSCRIPTIONal
CPG32_RS00925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPG32_RS00930	COG2076	Multidrug Resistance protein
CPG32_RS00935	COG2076	Multidrug Resistance protein
CPG32_RS00940	COG3942	CHAP domain
CPG32_RS00955	COG1757	Na H antiporter
CPG32_RS00960	COG3942	CHAP domain
CPG32_RS00990	COG1960	acyl-CoA dehydrogenase activity
CPG32_RS00995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPG32_RS01005	COG1268	BioY protein
CPG32_RS01015	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CPG32_RS01020	COG0725	ABC transporter, periplasmic molybdate-binding protein
CPG32_RS01025	COG4149	molybdate abc transporter
CPG32_RS01030	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CPG32_RS01035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CPG32_RS01070	COG0746	molybdenum cofactor guanylyltransferase activity
CPG32_RS01075	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CPG32_RS01100	COG2348	transferase activity, transferring amino-acyl groups
CPG32_RS01105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CPG32_RS01135	COG2252	PERMEase
CPG32_RS01150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CPG32_RS01155	COG0088	Forms part of the polypeptide exit tunnel
CPG32_RS01160	COG0089	rRNA binding
CPG32_RS01165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CPG32_RS01170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CPG32_RS01180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CPG32_RS01185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CPG32_RS01195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CPG32_RS01205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CPG32_RS01220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CPG32_RS01225	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CPG32_RS01230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CPG32_RS01235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CPG32_RS01240	COG1841	ribosomal large subunit assembly
CPG32_RS01250	COG0201	protein transport
CPG32_RS01255	COG0563	adenylate kinase activity
CPG32_RS01260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CPG32_RS01265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CPG32_RS01270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CPG32_RS01280	COG0202	RNA polymerase activity
CPG32_RS01285	COG0203	ribosomal protein L17
CPG32_RS01295	COG1122	ATPase activity
CPG32_RS01305	COG0101	tRNA pseudouridine synthase activity
CPG32_RS01310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CPG32_RS01330	COG1131	(ABC) transporter
CPG32_RS01340	COG1131	(ABC) transporter
CPG32_RS01350	COG1309	transcriptional regulator
CPG32_RS01390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CPG32_RS01395	COG1349	DNA-binding transcription factor activity
CPG32_RS01400	COG0698	ribose 5-phosphate isomerase
CPG32_RS01405	COG0698	ribose 5-phosphate isomerase
CPG32_RS01410	COG1105	Belongs to the carbohydrate kinase PfkB family
CPG32_RS01415	COG3684	Belongs to the aldolase LacD family
CPG32_RS01420	COG1447	Phosphotransferase system cellobiose-specific component IIA
CPG32_RS01425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CPG32_RS01425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CPG32_RS01430	COG2723	6-phospho-beta-galactosidase activity
CPG32_RS01440	COG2130	NADP-dependent
CPG32_RS01445	COG0604	alcohol dehydrogenase
CPG32_RS01475	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CPG32_RS01480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPG32_RS01485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPG32_RS01490	COG3314	Sporulation integral membrane protein YlbJ
CPG32_RS01500	COG1988	membrane-bound metal-dependent
CPG32_RS01505	COG4284	Utp--glucose-1-phosphate uridylyltransferase
CPG32_RS01510	COG1272	protein, Hemolysin III
CPG32_RS01525	COG2814	Major facilitator Superfamily
CPG32_RS01530	COG0489	protein tyrosine kinase activity
CPG32_RS01600	COG0561	phosphatase activity
CPG32_RS01620	COG0640	Transcriptional regulator
CPG32_RS01625	COG0702	epimerase
CPG32_RS01630	COG1482	cell wall glycoprotein biosynthetic process
CPG32_RS01650	COG0783	Belongs to the Dps family
CPG32_RS01655	COG0813	purine-nucleoside phosphorylase activity
CPG32_RS01660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CPG32_RS01665	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CPG32_RS01670	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CPG32_RS01700	COG1854	S-ribosylhomocysteine lyase activity
CPG32_RS01720	COG5146	pantothenate kinase activity
CPG32_RS01730	COG3343	RNA polymerase activity
CPG32_RS01735	COG0504	CTP synthase activity
CPG32_RS01745	COG0191	fructose-bisphosphate aldolase activity
CPG32_RS01750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CPG32_RS01760	COG1012	belongs to the aldehyde dehydrogenase family
CPG32_RS01765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CPG32_RS01770	COG0254	rRNA binding
CPG32_RS01780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CPG32_RS01785	COG2890	protein-(glutamine-N5) methyltransferase activity
CPG32_RS01790	COG0009	L-threonylcarbamoyladenylate synthase
CPG32_RS01800	COG4475	Protein of unknown function (DUF436)
CPG32_RS01805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CPG32_RS01820	COG0356	it plays a direct role in the translocation of protons across the membrane
CPG32_RS01825	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CPG32_RS01830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CPG32_RS01835	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CPG32_RS01845	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CPG32_RS01850	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CPG32_RS01860	COG4836	Membrane
CPG32_RS01865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CPG32_RS01870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CPG32_RS01900	COG0629	single-stranded DNA binding
CPG32_RS01910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CPG32_RS01920	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CPG32_RS01925	COG0352	thiamine-phosphate diphosphorylase activity
CPG32_RS01930	COG0706	membrane insertase activity
CPG32_RS01935	COG1418	mRNA catabolic process
CPG32_RS01940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CPG32_RS01945	COG1937	Protein conserved in bacteria
CPG32_RS01960	COG0772	Belongs to the SEDS family
CPG32_RS01965	COG1181	Belongs to the D-alanine--D-alanine ligase family
CPG32_RS01970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CPG32_RS01975	COG0513	Belongs to the DEAD box helicase family
CPG32_RS01985	COG3428	Bacterial PH domain
CPG32_RS01995	COG0736	holo-[acyl-carrier-protein] synthase activity
CPG32_RS02010	COG2337	Toxic component of a toxin-antitoxin (TA) module
CPG32_RS02015	COG2208	phosphoserine phosphatase activity
CPG32_RS02030	COG1191	sigma factor activity
CPG32_RS02035	COG2183	response to ionizing radiation
CPG32_RS02075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CPG32_RS02085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CPG32_RS02095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CPG32_RS02100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CPG32_RS02110	COG0028	Belongs to the TPP enzyme family
CPG32_RS02120	COG0802	atpase or kinase
CPG32_RS02125	COG1214	PFAM Peptidase M22, glycoprotease
CPG32_RS02130	COG0456	acetyltransferase
CPG32_RS02135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CPG32_RS02140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CPG32_RS02145	COG0488	(ABC) transporter
CPG32_RS02150	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CPG32_RS02160	COG2391	methyltransferase activity
CPG32_RS02165	COG0425	Belongs to the sulfur carrier protein TusA family
CPG32_RS02170	COG0004	ammonium transporteR
CPG32_RS02175	COG1609	Transcriptional regulator
CPG32_RS02180	COG1621	beta-fructofuranosidase activity
CPG32_RS02185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPG32_RS02195	COG3290	protein histidine kinase activity
CPG32_RS02205	COG4512	PFAM Accessory gene regulator B
CPG32_RS02210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CPG32_RS02235	COG0459	protein refolding
CPG32_RS02240	COG0582	viral genome integration into host DNA
CPG32_RS02310	COG5484	DNA packaging
CPG32_RS02310	COG3728	DNA packaging
CPG32_RS02330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPG32_RS02335	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CPG32_RS02340	COG0436	Aminotransferase
CPG32_RS02355	COG1725	Transcriptional regulator
CPG32_RS02360	COG1129	ABC transporter
CPG32_RS02360	COG0842	Transport permease protein
CPG32_RS02370	COG1131	(ABC) transporter
CPG32_RS02410	COG2706	6-phosphogluconolactonase activity
CPG32_RS02415	COG1012	belongs to the aldehyde dehydrogenase family
CPG32_RS02420	COG1227	inorganic diphosphatase activity
CPG32_RS02425	COG1335	isochorismatase
CPG32_RS02440	COG0077	Prephenate dehydratase
CPG32_RS02450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CPG32_RS02455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CPG32_RS02460	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CPG32_RS02470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CPG32_RS02475	COG4496	protein, YerC YecD
CPG32_RS02480	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CPG32_RS02490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CPG32_RS02495	COG4851	CamS sex pheromone cAM373 precursor
CPG32_RS02505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPG32_RS02515	COG0154	amidase activity
CPG32_RS02520	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CPG32_RS02525	COG1597	lipid kinase activity
CPG32_RS02530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CPG32_RS02555	COG1528	Iron-storage protein
CPG32_RS02575	COG0446	pyridine nucleotide-disulphide oxidoreductase
CPG32_RS02580	COG4129	membrane
CPG32_RS02585	COG0024	Methionine aminopeptidase
CPG32_RS02610	COG1295	ribonuclease BN
CPG32_RS02620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CPG32_RS02625	COG4840	Belongs to the UPF0435 family
CPG32_RS02630	COG2309	aminopeptidase activity
CPG32_RS02635	COG1607	acyl-coa hydrolase
CPG32_RS02640	COG0535	radical SAM domain protein
CPG32_RS02650	COG0693	protein deglycase activity
CPG32_RS02655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CPG32_RS02660	COG2137	regulation of response to DNA damage stimulus
CPG32_RS02670	COG1388	LysM domain
CPG32_RS02670	COG1134	teichoic acid transport
CPG32_RS02680	COG1988	membrane-bound metal-dependent
CPG32_RS02685	COG1194	a g-specific adenine glycosylase
CPG32_RS02690	COG3557	Belongs to the UPF0374 family
CPG32_RS02700	COG4129	membrane
CPG32_RS02705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CPG32_RS02710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CPG32_RS02720	COG0735	belongs to the Fur family
CPG32_RS02885	COG0765	amino acid transport
CPG32_RS02890	COG1126	abc transporter atp-binding protein
CPG32_RS02895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CPG32_RS02905	COG0363	glucosamine-6-phosphate deaminase activity
CPG32_RS02920	COG0114	fumarate hydratase activity
CPG32_RS02925	COG0564	pseudouridine synthase activity
CPG32_RS02930	COG4585	Histidine kinase
CPG32_RS02930	COG2203	Gaf domain
CPG32_RS02935	COG2197	response regulator
CPG32_RS02950	COG3679	Belongs to the UPF0342 family
CPG32_RS02955	COG0420	3'-5' exonuclease activity
CPG32_RS02980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CPG32_RS02995	COG0537	adenosine 5'-monophosphoramidase activity
CPG32_RS03000	COG1131	(ABC) transporter
CPG32_RS03005	COG4473	ABC transporter
CPG32_RS03010	COG2329	Antibiotic biosynthesis monooxygenase
CPG32_RS03015	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CPG32_RS03025	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CPG32_RS03030	COG3545	Serine hydrolase
CPG32_RS03080	COG0318	PFAM AMP-dependent synthetase and ligase
CPG32_RS03090	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CPG32_RS03100	COG1506	peptidase
CPG32_RS03105	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CPG32_RS03110	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CPG32_RS03120	COG0656	L-ascorbic acid biosynthetic process
CPG32_RS03125	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CPG32_RS03140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CPG32_RS03165	COG4193	domain, Protein
CPG32_RS03165	COG5632	N-Acetylmuramoyl-L-alanine amidase
CPG32_RS03165	COG3266	domain, Protein
CPG32_RS03175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CPG32_RS03175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CPG32_RS03185	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPG32_RS03185	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPG32_RS03190	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CPG32_RS03195	COG0506	proline dehydrogenase activity
CPG32_RS03200	COG2267	carboxylic ester hydrolase activity
CPG32_RS03210	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CPG32_RS03215	COG1242	4 iron, 4 sulfur cluster binding
CPG32_RS03220	COG2814	Major facilitator Superfamily
CPG32_RS03225	COG0495	leucyl-tRNA aminoacylation
CPG32_RS03235	COG2081	HI0933 family
CPG32_RS03240	COG2244	polysaccharide biosynthetic process
CPG32_RS03245	COG1187	pseudouridine synthase activity
CPG32_RS03255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPG32_RS03265	COG0510	thiamine kinase activity
CPG32_RS03270	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CPG32_RS03275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPG32_RS03280	COG5584	Small secreted protein
CPG32_RS03285	COG1363	Peptidase, m42
CPG32_RS03290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CPG32_RS03295	COG4848	Belongs to the UPF0354 family
CPG32_RS03300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPG32_RS03305	COG1674	ftsk spoiiie
CPG32_RS03310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CPG32_RS03315	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CPG32_RS03325	COG1605	Chorismate mutase
CPG32_RS03325	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CPG32_RS03330	COG1609	Transcriptional regulator
CPG32_RS03350	COG0123	including yeast histone deacetylase and acetoin utilization protein
CPG32_RS03355	COG0454	-acetyltransferase
CPG32_RS03360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CPG32_RS03365	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CPG32_RS03375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CPG32_RS03380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPG32_RS03385	COG0204	Acyl-transferase
CPG32_RS03390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPG32_RS03390	COG1263	PTS System
CPG32_RS03400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CPG32_RS03405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CPG32_RS03410	COG1764	response to oxidative stress
CPG32_RS03415	COG0584	glycerophosphoryl diester phosphodiesterase
CPG32_RS03420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CPG32_RS03430	COG1956	GAF domain-containing protein
CPG32_RS03435	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CPG32_RS03440	COG1104	cysteine desulfurase activity
CPG32_RS03445	COG0301	tRNA thio-modification
CPG32_RS03450	COG0730	response to heat
CPG32_RS03455	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CPG32_RS03460	COG0827	DNA restriction-modification system
CPG32_RS03465	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CPG32_RS03470	COG0589	response to stress
CPG32_RS03475	COG0686	Belongs to the AlaDH PNT family
CPG32_RS03480	COG0006	proline dipeptidase activity
CPG32_RS03485	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CPG32_RS03495	COG4109	DRTGG domain
CPG32_RS03500	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CPG32_RS03505	COG0587	DNA-directed DNA polymerase activity
CPG32_RS03510	COG0281	malic enzyme
CPG32_RS03515	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CPG32_RS03520	COG0825	malonyl-CoA metabolic process
CPG32_RS03525	COG0205	6-phosphofructokinase activity
CPG32_RS03530	COG0469	pyruvate kinase activity
CPG32_RS03540	COG1113	amino acid transport
CPG32_RS03545	COG0372	Belongs to the citrate synthase family
CPG32_RS03550	COG0538	isocitrate dehydrogenase activity
CPG32_RS03555	COG0745	RESPONSE REGULATOR receiver
CPG32_RS03560	COG5002	protein histidine kinase activity
CPG32_RS03565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPG32_RS03565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPG32_RS03570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CPG32_RS03575	COG0237	dephospho-CoA kinase activity
CPG32_RS03580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CPG32_RS03585	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CPG32_RS03590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CPG32_RS03595	COG3611	Membrane attachment protein
CPG32_RS03600	COG1484	DNA-dependent DNA replication
CPG32_RS03610	COG0833	amino acid
CPG32_RS03615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CPG32_RS03620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CPG32_RS03625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CPG32_RS03630	COG4112	unkown
CPG32_RS03640	COG0544	peptidyl-prolyl cis-trans isomerase activity
CPG32_RS03645	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CPG32_RS03660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CPG32_RS03665	COG0181	hydroxymethylbilane synthase activity
CPG32_RS03680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CPG32_RS03690	COG2818	Glycosylase
CPG32_RS03695	COG0525	valine-tRNA ligase activity
CPG32_RS03700	COG0285	dihydrofolate synthase activity
CPG32_RS03710	COG2003	Belongs to the UPF0758 family
CPG32_RS03730	COG1792	Involved in formation and maintenance of cell shape
CPG32_RS03740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CPG32_RS03745	COG2868	ribosomal protein
CPG32_RS03755	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CPG32_RS03760	COG4492	Belongs to the UPF0735 family
CPG32_RS03765	COG0632	four-way junction helicase activity
CPG32_RS03770	COG2255	four-way junction helicase activity
CPG32_RS03775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CPG32_RS03780	COG0343	queuine tRNA-ribosyltransferase activity
CPG32_RS03785	COG1862	Preprotein translocase
CPG32_RS03790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPG32_RS03790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPG32_RS03795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CPG32_RS03795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CPG32_RS03805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPG32_RS03810	COG1490	D-aminoacyl-tRNA deacylase activity
CPG32_RS03815	COG0860	N-Acetylmuramoyl-L-alanine amidase
CPG32_RS03820	COG0124	histidyl-tRNA synthetase
CPG32_RS03825	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CPG32_RS03835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CPG32_RS03840	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CPG32_RS03845	COG1959	2 iron, 2 sulfur cluster binding
CPG32_RS03855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CPG32_RS03860	COG1104	cysteine desulfurase activity
CPG32_RS03865	COG0482	sulfurtransferase activity
CPG32_RS03875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CPG32_RS03880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CPG32_RS03885	COG4472	Bacterial protein of unknown function (DUF965)
CPG32_RS03890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CPG32_RS03900	COG4122	O-methyltransferase activity
CPG32_RS03905	COG0826	peptidase U32
CPG32_RS03910	COG0826	peptidase U32
CPG32_RS03915	COG0572	uridine kinase
CPG32_RS03920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CPG32_RS03925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CPG32_RS03930	COG1984	allophanate hydrolase subunit 2
CPG32_RS03935	COG0511	ligase activity, forming carbon-carbon bonds
CPG32_RS03940	COG0439	Biotin carboxylase
CPG32_RS03950	COG1914	H( )-stimulated, divalent metal cation uptake system
CPG32_RS03955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CPG32_RS03960	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CPG32_RS03965	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CPG32_RS03975	COG1534	Rna-binding protein
CPG32_RS03980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CPG32_RS03985	COG1713	HD superfamily hydrolase involved in NAD metabolism
CPG32_RS03990	COG0799	negative regulation of ribosome biogenesis
CPG32_RS03995	COG2226	methyltransferase
CPG32_RS04000	COG1596	polysaccharide export
CPG32_RS04000	COG1555	photosystem II stabilization
CPG32_RS04005	COG2131	deaminase
CPG32_RS04010	COG0658	competence protein
CPG32_RS04010	COG2333	competence protein COMEC
CPG32_RS04015	COG1466	dna polymerase III delta subunit
CPG32_RS04020	COG0268	Binds directly to 16S ribosomal RNA
CPG32_RS04025	COG0481	GTPase activity
CPG32_RS04030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPG32_RS04040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CPG32_RS04045	COG0443	Heat shock 70 kDa protein
CPG32_RS04050	COG0484	heat shock protein binding
CPG32_RS04055	COG2264	protein methyltransferase activity
CPG32_RS04060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CPG32_RS04065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPG32_RS04075	COG1030	water channel activity
CPG32_RS04080	COG4864	UPF0365 protein
CPG32_RS04090	COG1702	phosphate starvation-inducible protein PhoH
CPG32_RS04095	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CPG32_RS04100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CPG32_RS04105	COG0295	cytidine deaminase activity
CPG32_RS04110	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CPG32_RS04115	COG1381	Involved in DNA repair and RecF pathway recombination
CPG32_RS04120	COG0423	glycine-tRNA ligase activity
CPG32_RS04125	COG0517	IMP dehydrogenase activity
CPG32_RS04130	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CPG32_RS04145	COG2384	SAM-dependent methyltransferase
CPG32_RS04155	COG0513	Belongs to the DEAD box helicase family
CPG32_RS04160	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CPG32_RS04165	COG1121	(ABC) transporter
CPG32_RS04170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPG32_RS04180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CPG32_RS04185	COG0768	penicillin binding
CPG32_RS04190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CPG32_RS04195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CPG32_RS04200	COG0705	Rhomboid family
CPG32_RS04200	COG0457	Tetratricopeptide repeat
CPG32_RS04205	COG4483	Protein conserved in bacteria
CPG32_RS04210	COG1940	carbohydrate kinase activity
CPG32_RS04215	COG0011	TIGRFAM Protein of
CPG32_RS04220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPG32_RS04225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CPG32_RS04230	COG1459	type II secretion system
CPG32_RS04235	COG4537	Required for transformation and DNA binding
CPG32_RS04260	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CPG32_RS04265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CPG32_RS04270	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CPG32_RS04275	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CPG32_RS04280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CPG32_RS04285	COG0095	Lipoate-protein ligase
CPG32_RS04305	COG0006	proline dipeptidase activity
CPG32_RS04310	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CPG32_RS04315	COG0511	ligase activity, forming carbon-carbon bonds
CPG32_RS04320	COG0439	Biotin carboxylase
CPG32_RS04325	COG1302	Protein conserved in bacteria
CPG32_RS04330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CPG32_RS04350	COG1438	arginine binding
CPG32_RS04355	COG0497	DNA recombination
CPG32_RS04360	COG0280	phosphate acetyltransferase
CPG32_RS04365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPG32_RS04370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CPG32_RS04375	COG0022	dehydrogenase e1 component
CPG32_RS04380	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPG32_RS04390	COG4129	membrane
CPG32_RS04400	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPG32_RS04410	COG1609	Transcriptional regulator
CPG32_RS04415	COG0366	Alpha amylase catalytic
CPG32_RS04425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CPG32_RS04435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CPG32_RS04440	COG0300	oxidoreductase activity
CPG32_RS04445	COG0667	Aldo Keto reductase
CPG32_RS04450	COG0494	nUDIX hydrolase
CPG32_RS04455	COG0735	belongs to the Fur family
CPG32_RS04460	COG4974	Belongs to the 'phage' integrase family
CPG32_RS04470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CPG32_RS04475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CPG32_RS04480	COG1187	pseudouridine synthase activity
CPG32_RS04485	COG0745	RESPONSE REGULATOR receiver
CPG32_RS04500	COG1141	Ferredoxin
CPG32_RS04510	COG0514	ATP-dependent DNA helicase (RecQ)
CPG32_RS04515	COG1388	LysM domain
CPG32_RS04520	COG0492	ferredoxin-NADP+ reductase activity
CPG32_RS04540	COG0539	negative regulation of cytoplasmic translation
CPG32_RS04550	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CPG32_RS04565	COG2226	methyltransferase
CPG32_RS04570	COG0142	geranyltranstransferase activity
CPG32_RS04580	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CPG32_RS04585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CPG32_RS04610	COG2738	Putative neutral zinc metallopeptidase
CPG32_RS04615	COG1694	Mazg nucleotide pyrophosphohydrolase
CPG32_RS04620	COG0438	transferase activity, transferring glycosyl groups
CPG32_RS04625	COG0617	tRNA 3'-terminal CCA addition
CPG32_RS04630	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CPG32_RS04630	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CPG32_RS04635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CPG32_RS04635	COG1199	ATP-dependent helicase activity
CPG32_RS04640	COG0017	Asparaginyl-tRNA synthetase
CPG32_RS04645	COG3935	DnaD domain protein
CPG32_RS04650	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CPG32_RS04660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CPG32_RS04660	COG4499	WXG100 protein secretion system (Wss), protein YukC
CPG32_RS04675	COG4474	Belongs to the UPF0398 family
CPG32_RS04680	COG3599	regulation of cell shape
CPG32_RS04690	COG0116	Belongs to the methyltransferase superfamily
CPG32_RS04700	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CPG32_RS04705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPG32_RS04710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CPG32_RS04715	COG0512	Glutamine amidotransferase of anthranilate synthase
CPG32_RS04720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CPG32_RS04725	COG0134	indole-3-glycerol-phosphate synthase activity
CPG32_RS04730	COG0135	phosphoribosylanthranilate isomerase activity
CPG32_RS04745	COG2348	transferase activity, transferring amino-acyl groups
CPG32_RS04755	COG0561	phosphatase activity
CPG32_RS04760	COG4607	ABC-type enterochelin transport system periplasmic component
CPG32_RS04770	COG1164	Oligoendopeptidase f
CPG32_RS04780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CPG32_RS04785	COG0581	inorganic phosphate transmembrane transporter activity
CPG32_RS04790	COG0573	inorganic phosphate transmembrane transporter activity
CPG32_RS04795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CPG32_RS04800	COG2996	Protein conserved in bacteria
CPG32_RS04805	COG0488	(ABC) transporter
CPG32_RS04810	COG0527	aspartate kinase activity
CPG32_RS04815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CPG32_RS04820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CPG32_RS04825	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CPG32_RS04830	COG2171	N-acyltransferase activity
CPG32_RS04835	COG1473	amidohydrolase
CPG32_RS04855	COG1278	Cold shock
CPG32_RS04865	COG1254	Belongs to the acylphosphatase family
CPG32_RS04875	COG3853	Toxic anion resistance protein (TelA)
CPG32_RS04880	COG1114	Component of the transport system for branched-chain amino acids
CPG32_RS04885	COG4548	von Willebrand factor, type A
CPG32_RS04890	COG0714	Associated with various cellular activities
CPG32_RS04910	COG0567	Dehydrogenase, E1 component
CPG32_RS04915	COG5002	protein histidine kinase activity
CPG32_RS04920	COG0745	RESPONSE REGULATOR receiver
CPG32_RS04925	COG0671	phosphoesterase, PA-phosphatase related
CPG32_RS04930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CPG32_RS04940	COG0793	Belongs to the peptidase S41A family
CPG32_RS04945	COG4479	Belongs to the UPF0346 family
CPG32_RS04955	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPG32_RS04985	COG1413	lyase activity
CPG32_RS04995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CPG32_RS05000	COG0328	RNA-DNA hybrid ribonuclease activity
CPG32_RS05005	COG1363	Peptidase, m42
CPG32_RS05020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPG32_RS05030	COG3623	hexulose-6-phosphate isomerase
CPG32_RS05050	COG0287	Prephenate dehydrogenase
CPG32_RS05055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CPG32_RS05060	COG1942	4-Oxalocrotonate Tautomerase
CPG32_RS05090	COG0392	lysyltransferase activity
CPG32_RS05090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CPG32_RS05095	COG0628	permease
CPG32_RS05100	COG1115	amino acid carrier protein
CPG32_RS05105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CPG32_RS05110	COG0187	DNA topoisomerase II activity
CPG32_RS05115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CPG32_RS05120	COG4841	protein insertion into membrane
CPG32_RS05130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CPG32_RS05135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPG32_RS05140	COG1970	mechanosensitive ion channel activity
CPG32_RS05145	COG0419	ATPase involved in DNA repair
CPG32_RS05155	COG4846	Membrane protein involved in cytochrome C biogenesis
CPG32_RS05160	COG3763	UPF0154 protein
CPG32_RS05165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CPG32_RS05170	COG4224	UPF0291 protein
CPG32_RS05180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CPG32_RS05185	COG2340	Cysteine-rich secretory protein family
CPG32_RS05195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CPG32_RS05210	COG0833	amino acid
CPG32_RS05220	COG0561	phosphatase activity
CPG32_RS05225	COG0083	homoserine kinase activity
CPG32_RS05230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CPG32_RS05235	COG0460	homoserine dehydrogenase
CPG32_RS05255	COG1525	nuclease
CPG32_RS05270	COG2197	response regulator
CPG32_RS05275	COG4585	Histidine kinase
CPG32_RS05275	COG2203	Gaf domain
CPG32_RS05285	COG1131	(ABC) transporter
CPG32_RS05290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CPG32_RS05305	COG0789	Transcriptional regulator
CPG32_RS05310	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CPG32_RS05315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CPG32_RS05325	COG1923	regulation of RNA biosynthetic process
CPG32_RS05330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CPG32_RS05340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CPG32_RS05345	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CPG32_RS05350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CPG32_RS05360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CPG32_RS05365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CPG32_RS05380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPG32_RS05395	COG4195	phage-related replication protein
CPG32_RS05400	COG1013	pyruvate-flavodoxin oxidoreductase activity
CPG32_RS05405	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CPG32_RS05405	COG0674	pyruvate-flavodoxin oxidoreductase activity
CPG32_RS05410	COG1692	metallophosphoesterase
CPG32_RS05420	COG1418	mRNA catabolic process
CPG32_RS05425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CPG32_RS05430	COG1546	Belongs to the CinA family
CPG32_RS05430	COG1058	Belongs to the CinA family
CPG32_RS05450	COG0300	oxidoreductase activity
CPG32_RS05455	COG0612	Peptidase, M16
CPG32_RS05460	COG0612	Peptidase, M16
CPG32_RS05465	COG2188	Transcriptional regulator
CPG32_RS05470	COG1674	ftsk spoiiie
CPG32_RS05475	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CPG32_RS05480	COG1185	polyribonucleotide nucleotidyltransferase activity
CPG32_RS05490	COG0196	riboflavin kinase activity
CPG32_RS05500	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CPG32_RS05505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CPG32_RS05510	COG1358	cellular component organization or biogenesis
CPG32_RS05515	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CPG32_RS05520	COG0195	Participates in both transcription termination and antitermination
CPG32_RS05525	COG0779	Required for maturation of 30S ribosomal subunits
CPG32_RS05530	COG2176	DNA-directed DNA polymerase activity
CPG32_RS05535	COG0442	prolyl-tRNA aminoacylation
CPG32_RS05550	COG4589	Belongs to the CDS family
CPG32_RS05555	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CPG32_RS05560	COG0233	cytoplasmic translational termination
CPG32_RS05565	COG0528	UMP kinase activity
CPG32_RS05570	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CPG32_RS05575	COG0052	Belongs to the universal ribosomal protein uS2 family
CPG32_RS05580	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CPG32_RS05585	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CPG32_RS05590	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CPG32_RS05595	COG4974	Belongs to the 'phage' integrase family
CPG32_RS05600	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CPG32_RS05605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPG32_RS05610	COG0758	DNA mediated transformation
CPG32_RS05620	COG2348	transferase activity, transferring amino-acyl groups
CPG32_RS05625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CPG32_RS05630	COG0045	succinate-CoA ligase (ADP-forming) activity
CPG32_RS05635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CPG32_RS05645	COG4485	Bacterial membrane protein, YfhO
CPG32_RS05655	COG0335	large ribosomal subunit rRNA binding
CPG32_RS05660	COG0336	Belongs to the RNA methyltransferase TrmD family
CPG32_RS05665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CPG32_RS05670	COG0228	four-way junction DNA binding
CPG32_RS05685	COG0183	Belongs to the thiolase family
CPG32_RS05690	COG0318	PFAM AMP-dependent synthetase and ligase
CPG32_RS05700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CPG32_RS05705	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CPG32_RS05710	COG0552	protein localization to endoplasmic reticulum
CPG32_RS05715	COG1196	nuclear chromosome segregation
CPG32_RS05720	COG0571	ribonuclease III activity
CPG32_RS05725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CPG32_RS05740	COG0416	fatty acid biosynthetic process
CPG32_RS05745	COG1349	DNA-binding transcription factor activity
CPG32_RS05750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CPG32_RS05755	COG1461	Dihydroxyacetone kinase
CPG32_RS05760	COG1302	Protein conserved in bacteria
CPG32_RS05765	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CPG32_RS05775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CPG32_RS05790	COG0631	protein serine/threonine phosphatase activity
CPG32_RS05800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CPG32_RS05800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CPG32_RS05805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CPG32_RS05815	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CPG32_RS05820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CPG32_RS05825	COG1758	RNA polymerase activity
CPG32_RS05830	COG0194	GDP metabolic process
CPG32_RS05850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CPG32_RS05855	COG0284	orotidine-5'-phosphate decarboxylase activity
CPG32_RS05865	COG0505	Belongs to the CarA family
CPG32_RS05875	COG0540	Belongs to the ATCase OTCase family
CPG32_RS05880	COG2233	PERMEase
CPG32_RS05885	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CPG32_RS05890	COG0564	pseudouridine synthase activity
CPG32_RS05895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CPG32_RS05905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CPG32_RS05910	COG3599	regulation of cell shape
CPG32_RS05915	COG2302	S4 RNA-binding domain
CPG32_RS05920	COG0762	integral membrane protein
CPG32_RS05925	COG1799	cell septum assembly
CPG32_RS05930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CPG32_RS05935	COG1496	oxidoreductase activity
CPG32_RS05940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CPG32_RS05945	COG0849	cell division
CPG32_RS05950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CPG32_RS05955	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CPG32_RS05960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CPG32_RS05965	COG0768	penicillin binding
CPG32_RS05970	COG4839	cell division protein FtsL
CPG32_RS05975	COG0275	rRNA processing
CPG32_RS05985	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CPG32_RS05990	COG0454	-acetyltransferase
CPG32_RS06000	COG1011	Hydrolase
CPG32_RS06010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CPG32_RS06015	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CPG32_RS06020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CPG32_RS06025	COG1053	succinate dehydrogenase
CPG32_RS06030	COG2009	succinate dehydrogenase
CPG32_RS06035	COG0322	excinuclease ABC activity
CPG32_RS06040	COG3118	belongs to the thioredoxin family
CPG32_RS06045	COG1193	negative regulation of DNA recombination
CPG32_RS06050	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CPG32_RS06050	COG1796	DNA polymerase
CPG32_RS06060	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CPG32_RS06065	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CPG32_RS06075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPG32_RS06075	COG0072	phenylalanine-tRNA ligase activity
CPG32_RS06080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CPG32_RS06085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPG32_RS06090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CPG32_RS06105	COG1323	Belongs to the UPF0348 family
CPG32_RS06110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CPG32_RS06115	COG0742	ribosomal rna small subunit methyltransferase
CPG32_RS06135	COG3679	Belongs to the UPF0342 family
CPG32_RS06150	COG0109	protoheme IX farnesyltransferase activity
CPG32_RS06155	COG1612	heme a metabolic process
CPG32_RS06170	COG0772	Belongs to the SEDS family
CPG32_RS06175	COG4838	Belongs to the UPF0358 family
CPG32_RS06180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CPG32_RS06190	COG1217	gtp-binding protein TYPA
CPG32_RS06200	COG0483	inositol monophosphate 1-phosphatase activity
CPG32_RS06205	COG4493	Belongs to the UPF0637 family
CPG32_RS06225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CPG32_RS06230	COG1177	transmembrane transport
CPG32_RS06250	COG4476	Belongs to the UPF0223 family
CPG32_RS06265	COG0022	dehydrogenase e1 component
CPG32_RS06280	COG0242	peptide deformylase activity
CPG32_RS06285	COG5503	Protein of unknown function (DUF1447)
CPG32_RS06290	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CPG32_RS06300	COG0569	domain protein
CPG32_RS06315	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CPG32_RS06330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CPG32_RS06345	COG4172	Belongs to the ABC transporter superfamily
CPG32_RS06350	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CPG32_RS06355	COG0151	Belongs to the GarS family
CPG32_RS06360	COG0138	bifunctional purine biosynthesis protein purh
CPG32_RS06370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CPG32_RS06380	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPG32_RS06385	COG0047	phosphoribosylformylglycinamidine synthase activity
CPG32_RS06390	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPG32_RS06395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CPG32_RS06400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CPG32_RS06405	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CPG32_RS06410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CPG32_RS06415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CPG32_RS06415	COG1017	nitric oxide dioxygenase activity
CPG32_RS06425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CPG32_RS06435	COG1845	cytochrome c oxidase, subunit III
CPG32_RS06440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CPG32_RS06450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CPG32_RS06455	COG1316	TRANSCRIPTIONal
CPG32_RS06485	COG0436	Aminotransferase
CPG32_RS06490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CPG32_RS06495	COG0596	Alpha beta hydrolase
CPG32_RS06500	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CPG32_RS06505	COG1169	isochorismate synthase
CPG32_RS06510	COG1575	Belongs to the MenA family. Type 1 subfamily
CPG32_RS06585	COG4873	Protein conserved in bacteria
CPG32_RS06595	COG0737	Belongs to the 5'-nucleotidase family
CPG32_RS06600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CPG32_RS06605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPG32_RS06610	COG0861	Integral membrane protein TerC family
CPG32_RS06625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CPG32_RS06630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CPG32_RS06635	COG2814	Major facilitator Superfamily
CPG32_RS06640	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CPG32_RS06645	COG0789	Transcriptional regulator
CPG32_RS06650	COG4221	oxidoreductase activity
CPG32_RS06660	COG0628	permease
CPG32_RS06670	COG0475	glutathione-regulated potassium exporter activity
CPG32_RS06670	COG0569	domain protein
CPG32_RS06675	COG2239	Acts as a magnesium transporter
CPG32_RS06680	COG0564	pseudouridine synthase activity
CPG32_RS06690	COG2357	RelA SpoT domain protein
CPG32_RS06705	COG2346	COG2346, Truncated hemoglobins
CPG32_RS06710	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CPG32_RS06715	COG1164	Oligoendopeptidase f
CPG32_RS06730	COG1393	Belongs to the ArsC family
CPG32_RS06735	COG0180	Tryptophanyl-tRNA synthetase
CPG32_RS06740	COG2226	methyltransferase
CPG32_RS06745	COG4166	transmembrane transport
CPG32_RS06750	COG4608	Belongs to the ABC transporter superfamily
CPG32_RS06755	COG0444	Belongs to the ABC transporter superfamily
CPG32_RS06760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CPG32_RS06765	COG0601	transmembrane transport
CPG32_RS06780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CPG32_RS06790	COG0542	response to heat
CPG32_RS06800	COG0561	phosphatase activity
CPG32_RS06805	COG0446	pyridine nucleotide-disulphide oxidoreductase
CPG32_RS06820	COG1074	ATP-dependent DNA helicase activity
CPG32_RS06840	COG0398	Pfam SNARE associated Golgi protein
CPG32_RS06845	COG0166	Belongs to the GPI family
CPG32_RS06850	COG0137	argininosuccinate synthase activity
CPG32_RS06880	COG1902	pentaerythritol trinitrate reductase activity
CPG32_RS06885	COG1098	S1 RNA binding domain
CPG32_RS06890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CPG32_RS06900	COG2111	Na H antiporter
CPG32_RS06900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CPG32_RS06905	COG2111	Na H antiporter
CPG32_RS06910	COG1006	Multisubunit Na H antiporter MnhC subunit
CPG32_RS06915	COG0651	ATP synthesis coupled electron transport
CPG32_RS06920	COG1863	multisubunit Na H antiporter MnhE subunit
CPG32_RS06925	COG2212	antiporter activity
CPG32_RS06930	COG1320	monovalent cation:proton antiporter activity
CPG32_RS06940	COG2050	protein possibly involved in aromatic compounds catabolism
CPG32_RS06945	COG2056	Na+-H+ antiporter family
CPG32_RS06950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CPG32_RS06955	COG1252	NADH dehydrogenase
CPG32_RS06965	COG1132	(ABC) transporter
CPG32_RS06975	COG1129	ABC transporter
CPG32_RS07005	COG2226	methyltransferase
CPG32_RS07005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CPG32_RS07005	COG3433	isochorismatase activity
CPG32_RS07010	COG1021	2,3-dihydroxybenzoate-AMP ligase
CPG32_RS07025	COG0316	Belongs to the HesB IscA family
CPG32_RS07030	COG4844	belongs to the
CPG32_RS07035	COG1252	NADH dehydrogenase
CPG32_RS07040	COG4837	Protein of unknown function (DUF1462)
CPG32_RS07045	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CPG32_RS07050	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CPG32_RS07055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CPG32_RS07060	COG1696	Membrane protein involved in D-alanine export
CPG32_RS07065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CPG32_RS07075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPG32_RS07080	COG0647	UMP catabolic process
CPG32_RS07085	COG2445	Protein of unknown function DUF86
CPG32_RS07095	COG4470	Protein conserved in bacteria
CPG32_RS07100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CPG32_RS07105	COG0737	Belongs to the 5'-nucleotidase family
CPG32_RS07110	COG0730	response to heat
CPG32_RS07115	COG1801	Protein of unknown function DUF72
CPG32_RS07120	COG2070	2-Nitropropane dioxygenase
CPG32_RS07125	COG1253	flavin adenine dinucleotide binding
CPG32_RS07285	COG3942	CHAP domain
CPG32_RS07285	COG1388	LysM domain
CPG32_RS07305	COG0719	Fe-S assembly protein
CPG32_RS07310	COG0822	iron-sulfur transferase activity
CPG32_RS07320	COG0719	Fe-S assembly protein
CPG32_RS07325	COG0396	ATPase activity
CPG32_RS07345	COG1464	Belongs to the NlpA lipoprotein family
CPG32_RS07350	COG2011	ABC-type metal ion transport system permease component
CPG32_RS07355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPG32_RS07365	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CPG32_RS07370	COG0509	glycine decarboxylation via glycine cleavage system
CPG32_RS07375	COG1393	Belongs to the ArsC family
CPG32_RS07380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CPG32_RS07390	COG0710	3-dehydroquinate dehydratase activity
CPG32_RS07395	COG1764	response to oxidative stress
CPG32_RS07405	COG0588	phosphoglycerate mutase activity
CPG32_RS07440	COG4195	phage-related replication protein
CPG32_RS07455	COG2259	Doxx family
CPG32_RS07460	COG0346	lactoylglutathione lyase activity
CPG32_RS07470	COG1611	Belongs to the LOG family
CPG32_RS07565	COG0557	exoribonuclease II activity
CPG32_RS07570	COG1647	Serine aminopeptidase, S33
CPG32_RS07575	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPG32_RS07585	COG0148	phosphopyruvate hydratase activity
CPG32_RS07590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CPG32_RS07595	COG0149	triose-phosphate isomerase activity
CPG32_RS07600	COG0126	phosphoglycerate kinase activity
CPG32_RS07620	COG1090	epimerase
CPG32_RS07625	COG0740	serine-type endopeptidase activity
CPG32_RS07635	COG1481	regulation of sporulation
CPG32_RS07640	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CPG32_RS07645	COG1660	Displays ATPase and GTPase activities
CPG32_RS07650	COG0492	ferredoxin-NADP+ reductase activity
CPG32_RS07665	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CPG32_RS07670	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CPG32_RS07675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CPG32_RS07695	COG1388	LysM domain
CPG32_RS07695	COG3942	CHAP domain
CPG32_RS07705	COG0653	protein targeting
CPG32_RS07715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CPG32_RS07720	COG1040	competence protein
CPG32_RS07725	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CPG32_RS07735	COG1739	Uncharacterized protein family UPF0029
CPG32_RS07740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CPG32_RS07745	COG2199	diguanylate cyclase activity
CPG32_RS07760	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPG32_RS07765	COG1929	Belongs to the glycerate kinase type-1 family
CPG32_RS07785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CPG32_RS07795	COG4607	ABC-type enterochelin transport system periplasmic component
CPG32_RS07800	COG4604	ABC transporter, ATP-binding protein
CPG32_RS07805	COG4605	iron ion homeostasis
CPG32_RS07810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPG32_RS07815	COG4607	ABC-type enterochelin transport system periplasmic component
CPG32_RS07820	COG4604	ABC transporter, ATP-binding protein
CPG32_RS07825	COG4605	iron ion homeostasis
CPG32_RS07830	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPG32_RS07835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPG32_RS07840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CPG32_RS07845	COG1780	Probably involved in ribonucleotide reductase function
CPG32_RS07855	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CPG32_RS07860	COG3104	oligopeptide transport
CPG32_RS07865	COG1597	lipid kinase activity
CPG32_RS07875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CPG32_RS07880	COG3104	oligopeptide transport
CPG32_RS07885	COG1174	glycine betaine transport
CPG32_RS07895	COG0514	ATP-dependent DNA helicase (RecQ)
CPG32_RS07900	COG0488	(ABC) transporter
CPG32_RS07915	COG1368	sulfuric ester hydrolase activity
CPG32_RS07925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CPG32_RS07935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CPG32_RS07935	COG0512	Glutamine amidotransferase of anthranilate synthase
CPG32_RS07940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CPG32_RS07940	COG0512	Glutamine amidotransferase of anthranilate synthase
CPG32_RS07950	COG0720	synthase
CPG32_RS07965	COG0463	Glycosyl transferase, family 2
CPG32_RS07970	COG0656	L-ascorbic acid biosynthetic process
CPG32_RS07975	COG1253	flavin adenine dinucleotide binding
CPG32_RS07980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPG32_RS07980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPG32_RS07980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPG32_RS07985	COG1105	Belongs to the carbohydrate kinase PfkB family
CPG32_RS07990	COG1349	DNA-binding transcription factor activity
CPG32_RS07995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CPG32_RS08020	COG0415	Belongs to the DNA photolyase family
CPG32_RS08025	COG0471	metal ion transport
CPG32_RS08030	COG0039	L-malate dehydrogenase activity
CPG32_RS08040	COG0523	cobalamin synthesis protein
CPG32_RS08050	COG1968	undecaprenyl-diphosphatase activity
CPG32_RS08060	COG1671	Belongs to the UPF0178 family
CPG32_RS08065	COG1611	Belongs to the LOG family
CPG32_RS08090	COG2839	Protein conserved in bacteria
CPG32_RS08095	COG2814	Major facilitator Superfamily
CPG32_RS08100	COG0583	DNA-binding transcription factor activity
CPG32_RS08115	COG0217	transcriptional regulatory protein
CPG32_RS08135	COG3942	CHAP domain
CPG32_RS08135	COG1388	LysM domain
CPG32_RS08140	COG0306	phosphate transporter
CPG32_RS08145	COG1392	Phosphate transport regulator
CPG32_RS08150	COG0577	efflux transmembrane transporter activity
CPG32_RS08155	COG1136	(ABC) transporter
CPG32_RS08160	COG2205	protein histidine kinase activity
CPG32_RS08165	COG0745	RESPONSE REGULATOR receiver
CPG32_RS08170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CPG32_RS08180	COG0657	acetylesterase activity
CPG32_RS08185	COG3949	Membrane
CPG32_RS08195	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CPG32_RS08200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPG32_RS08205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPG32_RS08210	COG1120	ATPase activity
CPG32_RS08215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CPG32_RS08225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CPG32_RS08235	COG0463	Glycosyl transferase, family 2
CPG32_RS08235	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CPG32_RS08240	COG0438	transferase activity, transferring glycosyl groups
CPG32_RS08245	COG1132	(ABC) transporter
CPG32_RS08250	COG1686	Belongs to the peptidase S11 family
CPG32_RS08255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CPG32_RS08260	COG1215	transferase activity, transferring glycosyl groups
CPG32_RS08265	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CPG32_RS08275	COG1682	transport, permease protein
CPG32_RS08280	COG1134	teichoic acid transport
CPG32_RS08295	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CPG32_RS08305	COG1321	iron dependent repressor
CPG32_RS08310	COG1121	(ABC) transporter
CPG32_RS08315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CPG32_RS08320	COG0803	Belongs to the bacterial solute-binding protein 9 family
CPG32_RS08330	COG1320	monovalent cation:proton antiporter activity
CPG32_RS08335	COG2212	antiporter activity
CPG32_RS08340	COG1863	multisubunit Na H antiporter MnhE subunit
CPG32_RS08345	COG0651	ATP synthesis coupled electron transport
CPG32_RS08350	COG1006	Multisubunit Na H antiporter MnhC subunit
CPG32_RS08355	COG2111	Na H antiporter
CPG32_RS08360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CPG32_RS08360	COG2111	Na H antiporter
CPG32_RS08365	COG4974	Belongs to the 'phage' integrase family
CPG32_RS08395	COG0596	Alpha beta hydrolase
CPG32_RS08420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPG32_RS08425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPG32_RS08445	COG0018	arginyl-trna synthetase
CPG32_RS08465	COG1064	alcohol dehydrogenase
CPG32_RS08475	COG1078	dGTPase activity
CPG32_RS08485	COG0655	NAD(P)H dehydrogenase (quinone) activity
CPG32_RS08490	COG0667	Aldo Keto reductase
CPG32_RS08500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPG32_RS08505	COG4844	belongs to the
CPG32_RS08525	COG0095	Lipoate-protein ligase
CPG32_RS08535	COG3253	May function as heme-dependent peroxidase
CPG32_RS08565	COG0531	amino acid
CPG32_RS08570	COG2363	Small membrane protein
CPG32_RS08580	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CPG32_RS08615	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CPG32_RS08620	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CPG32_RS08630	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CPG32_RS08640	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CPG32_RS08665	COG0561	phosphatase activity
CPG32_RS08675	COG1428	Deoxynucleoside kinase
CPG32_RS08680	COG1428	Deoxynucleoside kinase
CPG32_RS08700	COG0531	amino acid
CPG32_RS08705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CPG32_RS08715	COG1279	arginine transmembrane transporter activity
CPG32_RS08740	COG1473	amidohydrolase
CPG32_RS08745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CPG32_RS08760	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CPG32_RS08770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CPG32_RS08775	COG0085	RNA polymerase activity
CPG32_RS08780	COG2813	Specifically methylates the guanine in position
CPG32_RS08785	COG0222	ribosome binding
CPG32_RS08790	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CPG32_RS08800	COG0081	regulation of translation
CPG32_RS08810	COG0250	Participates in transcription elongation, termination and antitermination
CPG32_RS08815	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CPG32_RS08820	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CPG32_RS08830	COG3688	RNA-binding protein containing a PIN domain
CPG32_RS08835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPG32_RS08840	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CPG32_RS08845	COG0215	cysteine-tRNA ligase activity
CPG32_RS08850	COG1045	serine acetyltransferase
CPG32_RS08855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CPG32_RS08860	COG4956	integral membrane protein (PIN domain superfamily)
CPG32_RS08865	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CPG32_RS08870	COG0542	response to heat
CPG32_RS08875	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CPG32_RS08880	COG3880	PFAM UvrB UvrC protein
CPG32_RS08885	COG4463	regulation of RNA biosynthetic process
CPG32_RS08890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CPG32_RS08895	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CPG32_RS08900	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CPG32_RS08905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CPG32_RS08990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CPG32_RS09000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CPG32_RS09005	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CPG32_RS09015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CPG32_RS09025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPG32_RS09040	COG1098	S1 RNA binding domain
CPG32_RS09050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CPG32_RS09055	COG3956	TIGRFAM MazG family protein
CPG32_RS09060	COG2244	polysaccharide biosynthetic process
CPG32_RS09065	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CPG32_RS09070	COG0193	aminoacyl-tRNA hydrolase activity
CPG32_RS09080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CPG32_RS09085	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CPG32_RS09095	COG0251	oxidation-reduction process
CPG32_RS09100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CPG32_RS09105	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CPG32_RS09110	COG4466	Protein conserved in bacteria
CPG32_RS09115	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CPG32_RS09120	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CPG32_RS09125	COG0084	hydrolase, TatD family'
CPG32_RS09130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPG32_RS09130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPG32_RS09135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CPG32_RS09145	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CPG32_RS09155	COG1774	PSP1 C-terminal conserved region
CPG32_RS09160	COG0470	DNA polymerase III
CPG32_RS09165	COG3870	Protein conserved in bacteria
CPG32_RS09170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CPG32_RS09175	COG1982	Orn Lys Arg decarboxylase major
CPG32_RS09210	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CPG32_RS09220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CPG32_RS09235	COG2188	Transcriptional regulator
CPG32_RS09240	COG0366	Alpha amylase catalytic
CPG32_RS09245	COG1263	PTS System
CPG32_RS09245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPG32_RS09255	COG0493	'glutamate synthase
CPG32_RS09260	COG0070	glutamate synthase
CPG32_RS09260	COG0069	glutamate synthase activity
CPG32_RS09260	COG0067	glutamate synthase
CPG32_RS09265	COG0583	DNA-binding transcription factor activity
CPG32_RS09295	COG1464	Belongs to the NlpA lipoprotein family
CPG32_RS09300	COG2011	ABC-type metal ion transport system permease component
CPG32_RS09305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPG32_RS09310	COG1132	(ABC) transporter
CPG32_RS09315	COG1132	(ABC) transporter
CPG32_RS09315	COG2375	cellular response to nickel ion
CPG32_RS09320	COG0626	cystathionine gamma-synthase activity
CPG32_RS09325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CPG32_RS09335	COG0733	neurotransmitter:sodium symporter activity
CPG32_RS09355	COG5609	conserved protein (DUF2294)
CPG32_RS09360	COG3002	Belongs to the UPF0753 family
CPG32_RS09365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CPG32_RS09375	COG0523	cobalamin synthesis protein
CPG32_RS09395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CPG32_RS09395	COG0519	Catalyzes the synthesis of GMP from XMP
CPG32_RS09400	COG0516	GMP reductase activity
CPG32_RS09400	COG0517	IMP dehydrogenase activity
CPG32_RS09405	COG2233	PERMEase
CPG32_RS09410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CPG32_RS09430	COG1823	symporter activity
CPG32_RS09440	COG0778	Nitroreductase
CPG32_RS09450	COG0450	alkyl hydroperoxide reductase
CPG32_RS09455	COG3634	alkyl hydroperoxide reductase activity
CPG32_RS09470	COG0588	phosphoglycerate mutase activity
CPG32_RS09515	COG5484	DNA packaging
CPG32_RS09515	COG3728	DNA packaging
CPG32_RS09585	COG0582	viral genome integration into host DNA
CPG32_RS09590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CPG32_RS09600	COG0360	Binds together with S18 to 16S ribosomal RNA
CPG32_RS09615	COG0012	GTP binding
CPG32_RS09620	COG4481	Protein conserved in bacteria
CPG32_RS09625	COG0668	transmembrane transport
CPG32_RS09630	COG1475	DNA binding
CPG32_RS09635	COG0626	cystathionine gamma-synthase activity
CPG32_RS09640	COG0626	cystathionine gamma-synthase activity
CPG32_RS09645	COG0646	methionine synthase
CPG32_RS09645	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CPG32_RS09650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CPG32_RS09675	COG0577	efflux transmembrane transporter activity
CPG32_RS09680	COG1136	(ABC) transporter
CPG32_RS09700	COG2205	protein histidine kinase activity
CPG32_RS09715	COG0745	RESPONSE REGULATOR receiver
CPG32_RS09740	COG3878	Protein conserved in bacteria
CPG32_RS09745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CPG32_RS09750	COG2271	Major facilitator Superfamily
CPG32_RS09765	COG1136	(ABC) transporter
CPG32_RS09770	COG0577	efflux transmembrane transporter activity
CPG32_RS09780	COG1396	sequence-specific DNA binding
CPG32_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
CPG32_RS09805	COG1063	alcohol dehydrogenase
CPG32_RS09825	COG1475	DNA binding
CPG32_RS09835	COG0445	tRNA wobble uridine modification
CPG32_RS09840	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CPG32_RS09845	COG0594	ribonuclease P activity
CPG32_RS09855	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CPG32_RS09860	COG0592	DNA-directed DNA polymerase activity
CPG32_RS09865	COG2501	S4 domain
CPG32_RS09870	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CPG32_RS09875	COG0187	DNA topoisomerase II activity
CPG32_RS09880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CPG32_RS09885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CPG32_RS09895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CPG32_RS09905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CPG32_RS09915	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CPG32_RS09920	COG0359	binds to the 23S rRNA
CPG32_RS09925	COG0305	Participates in initiation and elongation during chromosome replication
CPG32_RS09930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CPG32_RS09945	COG0745	RESPONSE REGULATOR receiver
CPG32_RS09950	COG5002	protein histidine kinase activity
CPG32_RS09955	COG4863	YycH protein
CPG32_RS09990	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CPG32_RS09995	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CPG32_RS10005	COG1522	sequence-specific DNA binding
CPG32_RS10030	COG1073	alpha beta
CPG32_RS10060	COG1129	ABC transporter
CPG32_RS10095	COG5002	protein histidine kinase activity
CPG32_RS10100	COG0745	RESPONSE REGULATOR receiver
CPG32_RS10115	COG1131	(ABC) transporter
CPG32_RS10175	COG2188	Transcriptional regulator
CPG32_RS10180	COG2222	sugar isomerase
CPG32_RS10185	COG3684	Belongs to the aldolase LacD family
CPG32_RS10190	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPG32_RS10195	COG3715	PTS system
CPG32_RS10200	COG3716	PTS system mannose fructose sorbose family IID component
CPG32_RS10215	COG0745	RESPONSE REGULATOR receiver
CPG32_RS10220	COG2205	protein histidine kinase activity
CPG32_RS10230	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CPG32_RS10235	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CPG32_RS10260	COG1129	ABC transporter
CPG32_RS10295	COG4509	Sortase family
CPG32_RS10305	COG1705	Flagellar rod assembly protein muramidase FlgJ
CPG32_RS10305	COG3942	CHAP domain
CPG32_RS10310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPG32_RS10315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CPG32_RS10320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CPG32_RS10325	COG2808	Putative FMN-binding domain
CPG32_RS10335	COG1846	Transcriptional regulator
CPG32_RS10350	COG3842	ATPase activity
CPG32_RS10355	COG4209	transmembrane transport
CPG32_RS10365	COG0395	ABC-type sugar transport system, permease component
CPG32_RS10375	COG0534	Mate efflux family protein
CPG32_RS10380	COG1349	DNA-binding transcription factor activity
CPG32_RS10390	COG5002	protein histidine kinase activity
CPG32_RS10425	COG0583	DNA-binding transcription factor activity
CPG32_RS10430	COG3842	ATPase activity
CPG32_RS10435	COG1840	ABC-type Fe3 transport system, periplasmic component
CPG32_RS10440	COG1177	transmembrane transport
CPG32_RS10445	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CPG32_RS10450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CPG32_RS10460	COG1114	Component of the transport system for branched-chain amino acids
CPG32_RS10470	COG0464	growth
CPG32_RS10475	COG0561	phosphatase activity
CPG32_RS10480	COG2814	Major facilitator Superfamily
CPG32_RS10495	COG0601	transmembrane transport
CPG32_RS10505	COG0444	Belongs to the ABC transporter superfamily
CPG32_RS10510	COG1124	(ABC) transporter
CPG32_RS10525	COG0693	protein deglycase activity
CPG32_RS10530	COG0531	amino acid
CPG32_RS10535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPG32_RS10535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPG32_RS10540	COG0505	Belongs to the CarA family
CPG32_RS10545	COG0657	acetylesterase activity
CPG32_RS10585	COG1033	growth of symbiont in host cell
CPG32_RS10585	COG2409	Drug exporters of the RND superfamily
CPG32_RS10605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CPG32_RS10620	COG1131	(ABC) transporter
CPG32_RS10635	COG1028	Short-chain dehydrogenase reductase Sdr
CPG32_RS10640	COG1278	Cold shock
CPG32_RS10655	COG2311	Membrane
CPG32_RS10660	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CPG32_RS10670	COG1233	COG1233 Phytoene dehydrogenase and related
CPG32_RS10690	COG2814	Major facilitator Superfamily
CPG32_RS10705	COG1131	(ABC) transporter
CPG32_RS10730	COG2264	protein methyltransferase activity
CPG32_RS10735	COG0747	negative chemotaxis
CPG32_RS10740	COG0601	transmembrane transport
CPG32_RS10750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPG32_RS10755	COG1124	(ABC) transporter
CPG32_RS10760	COG3961	Belongs to the TPP enzyme family
CPG32_RS10775	COG1131	(ABC) transporter
CPG32_RS10785	COG2353	YceI-like domain
CPG32_RS10790	COG1288	antiporter activity
CPG32_RS10800	COG2814	Major facilitator Superfamily
CPG32_RS10820	COG1028	Short-chain dehydrogenase reductase Sdr
CPG32_RS10830	COG1263	PTS System
CPG32_RS10830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPG32_RS10830	COG2190	(PTS) system
CPG32_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
CPG32_RS10865	COG3976	FMN-binding domain protein
CPG32_RS10865	COG1053	succinate dehydrogenase
CPG32_RS10865	COG0431	NADPH-dependent FMN reductase
CPG32_RS10880	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CPG32_RS10890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPG32_RS10895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CPG32_RS10900	COG0022	dehydrogenase e1 component
CPG32_RS10910	COG1695	Transcriptional regulator
CPG32_RS10935	COG3711	transcriptional antiterminator
CPG32_RS10935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPG32_RS10940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPG32_RS10940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CPG32_RS10940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPG32_RS10945	COG1482	cell wall glycoprotein biosynthetic process
CPG32_RS10950	COG2124	cytochrome p450
CPG32_RS10960	COG1846	Transcriptional regulator
CPG32_RS10965	COG2814	Major facilitator Superfamily
CPG32_RS10990	COG0706	membrane insertase activity
CPG32_RS11000	COG0531	amino acid
CPG32_RS11055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CPG32_RS11075	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CPG32_RS11085	COG0363	glucosamine-6-phosphate deaminase activity
CPG32_RS11090	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CPG32_RS11105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CPG32_RS11110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPG32_RS11115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CPG32_RS11150	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CPG32_RS11170	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CPG32_RS11175	COG3711	transcriptional antiterminator
CPG32_RS11175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPG32_RS11180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPG32_RS11195	COG1054	Belongs to the UPF0176 family
CPG32_RS11200	COG3386	PFAM SMP-30 Gluconolaconase
CPG32_RS11215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPG32_RS11225	COG1122	ATPase activity
CPG32_RS11235	COG1476	TRANSCRIPTIONal
CPG32_RS11270	COG3942	CHAP domain
CPG32_RS11270	COG1705	Flagellar rod assembly protein muramidase FlgJ
CPG32_RS11295	COG4974	Belongs to the 'phage' integrase family
CPG32_RS11325	COG3682	Transcriptional regulator
CPG32_RS11335	COG2235	arginine
CPG32_RS11345	COG2843	Capsule synthesis protein
CPG32_RS11350	COG4195	phage-related replication protein
CPG32_RS11355	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CPG32_RS11395	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CPG32_RS11430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CPG32_RS11435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CPG32_RS11440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CPG32_RS11445	COG1785	Belongs to the alkaline phosphatase family
CPG32_RS11460	COG2205	protein histidine kinase activity
CPG32_RS11465	COG1136	(ABC) transporter
CPG32_RS11495	COG1028	Short-chain dehydrogenase reductase Sdr
CPG32_RS11500	COG4932	domain protein
CPG32_RS11500	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CPG32_RS11500	COG3266	domain, Protein
CPG32_RS11500	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CPG32_RS11500	COG3266	domain, Protein
CPG32_RS11500	COG4932	domain protein
CPG32_RS11510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CPG32_RS11515	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CPG32_RS11530	COG0730	response to heat
CPG32_RS11535	COG2046	Belongs to the sulfate adenylyltransferase family
CPG32_RS11540	COG0529	Catalyzes the synthesis of activated sulfate
CPG32_RS11555	COG1328	CTP reductase activity
CPG32_RS11560	COG0602	queuosine metabolic process
CPG32_RS11565	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CPG32_RS11575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CPG32_RS11580	COG1510	regulation of RNA biosynthetic process
CPG32_RS11585	COG1012	belongs to the aldehyde dehydrogenase family
CPG32_RS11590	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CPG32_RS11595	COG1473	amidohydrolase
CPG32_RS11610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CPG32_RS11615	COG0574	Belongs to the PEP-utilizing enzyme family
CPG32_RS11615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CPG32_RS11620	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CPG32_RS11630	COG2188	Transcriptional regulator
CPG32_RS11635	COG1263	PTS System
CPG32_RS11635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CPG32_RS11635	COG2190	(PTS) system
CPG32_RS11640	COG2723	6-phospho-beta-galactosidase activity
CPG32_RS11650	COG0583	DNA-binding transcription factor activity
CPG32_RS11665	COG3588	fructose-bisphosphate aldolase
CPG32_RS11680	COG1464	Belongs to the NlpA lipoprotein family
CPG32_RS11690	COG0463	Glycosyl transferase, family 2
CPG32_RS11700	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CPG32_RS11700	COG1215	transferase activity, transferring glycosyl groups
CPG32_RS11710	COG0531	amino acid
CPG32_RS11715	COG0583	DNA-binding transcription factor activity
CPG32_RS11720	COG0028	Belongs to the TPP enzyme family
CPG32_RS11725	COG3527	Alpha-acetolactate decarboxylase
CPG32_RS11730	COG1620	l-lactate permease
CPG32_RS11750	COG0167	dihydroorotate dehydrogenase activity
CPG32_RS11755	COG3001	Fructosamine kinase
CPG32_RS11760	COG0596	Alpha beta hydrolase
CPG32_RS11810	COG2814	Major facilitator Superfamily
CPG32_RS11820	COG1113	amino acid transport
CPG32_RS11835	COG3189	MarR family transcriptional regulator
CPG32_RS11855	COG0436	Aminotransferase
CPG32_RS11870	COG2608	mercury ion transmembrane transporter activity
CPG32_RS11875	COG2217	Heavy metal translocating P-type atpase
CPG32_RS11885	COG0110	maltose O-acetyltransferase activity
CPG32_RS11890	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CPG32_RS11895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CPG32_RS11900	COG1012	belongs to the aldehyde dehydrogenase family
CPG32_RS11910	COG2409	Drug exporters of the RND superfamily
CPG32_RS11920	COG0598	Magnesium transport protein CorA
CPG32_RS11925	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CPG32_RS11950	COG1131	(ABC) transporter
CPG32_RS11960	COG3425	synthase
CPG32_RS11975	COG3942	CHAP domain
CPG32_RS11975	COG1388	LysM domain
CPG32_RS11985	COG0583	DNA-binding transcription factor activity
CPG32_RS11990	COG1380	Effector of murein hydrolase LrgA
CPG32_RS11995	COG1346	cytolysis
CPG32_RS12000	COG0028	Belongs to the TPP enzyme family
CPG32_RS12020	COG0039	L-malate dehydrogenase activity
CPG32_RS12025	COG0657	acetylesterase activity
CPG32_RS12035	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CPG32_RS12060	COG1070	Carbohydrate kinase
CPG32_RS12070	COG1760	l-serine dehydratase
CPG32_RS12075	COG1760	l-serine dehydratase
CPG32_RS12090	COG3764	Sortase (surface protein transpeptidase)
CPG32_RS12100	COG0561	phosphatase activity
CPG32_RS12105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPG32_RS12110	COG0778	Nitroreductase
CPG32_RS12120	COG1012	belongs to the aldehyde dehydrogenase family
CPG32_RS12125	COG2514	catechol 2,3-dioxygenase activity
CPG32_RS12130	COG2388	GCN5-related N-acetyl-transferase
CPG32_RS12150	COG1846	Transcriptional regulator
CPG32_RS12155	COG0346	lactoylglutathione lyase activity
CPG32_RS12160	COG0346	lactoylglutathione lyase activity
CPG32_RS12165	COG0400	carboxylic ester hydrolase activity
CPG32_RS12170	COG3949	Membrane
CPG32_RS12180	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CPG32_RS12185	COG0586	Pfam SNARE associated Golgi protein
CPG32_RS12195	COG2022	thiamine diphosphate biosynthetic process
CPG32_RS12215	COG2271	Major facilitator Superfamily
CPG32_RS12230	COG4876	unkown
CPG32_RS12235	COG2357	RelA SpoT domain protein
CPG32_RS12250	COG1802	Transcriptional regulator
CPG32_RS12255	COG1070	Carbohydrate kinase
CPG32_RS12260	COG2610	gluconate transmembrane transporter activity
CPG32_RS12265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CPG32_RS12280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPG32_RS12285	COG0438	transferase activity, transferring glycosyl groups
CPG32_RS12290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CPG32_RS12305	COG4221	oxidoreductase activity
CPG32_RS12310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPG32_RS12315	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CPG32_RS12325	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CPG32_RS12330	COG1363	Peptidase, m42
CPG32_RS12350	COG3639	organic phosphonate transmembrane transporter activity
CPG32_RS12355	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CPG32_RS12370	COG0737	Belongs to the 5'-nucleotidase family
CPG32_RS12375	COG0069	glutamate synthase activity
CPG32_RS12390	COG4619	ABC transporter
CPG32_RS12395	COG0390	transport system, permease component